Jan Drenth
Dutch chemist
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Chemistry
Jan Drenth's Degrees
- PhD Chemistry University of Amsterdam
- Masters Chemistry University of Amsterdam
- Bachelors Chemistry University of Amsterdam
Why Is Jan Drenth Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jan Drenth is a Dutch chemist. He was a professor of structural chemistry at the University of Groningen from 1969 to 1990. Career Drenth was born in Groningen. He obtained his PhD in mathematics and physics under Eelco Wiebenga at the University of Groningen in 1957, with a dissertation titled: Een röntgenografisch onderzoek van excelsine, edestine en tabakszaadglobuline. Drenth subsequently moved to New York, United States, where he became a post-doc and studied protein crystallography under Barbara Low. Drenth then returned to the Netherlands and in 1967 was appointed as lector. In 1969 he was appointed as professor of structural chemistry, which he remained until his retirement in 1990.
Jan Drenth's Published Works
Published Works
- Principles of protein x-ray crystallography (1994) (755)
- Structure of papain refined at 1.65 A resolution. (1984) (440)
- Structure of Papain (1968) (421)
- Structure of bovine pancreatic phospholipase A2 at 1.7A resolution. (1981) (350)
- A comparison of the crystal structures of phospholipase A2 from bovine pancreas and Crotalus atrox venom. (1985) (338)
- Binding of chloromethyl ketone substrate analogues to crystalline papain. (1977) (293)
- Methylation of histidine-48 in pancreatic phospholipase A2. Role of histidine and calcium ion in the catalytic mechanism. (1980) (261)
- Thiol proteases. Comparative studies based on the high-resolution structures of papain and actinidin, and on amino acid sequence information for cathepsins B and H, and stem bromelain. (1985) (260)
- Overexpression of TaNAC69 leads to enhanced transcript levels of stress up-regulated genes and dehydration tolerance in bread wheat. (2011) (224)
- X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor (1990) (208)
- Structure of porcine pancreatic phospholipase A2 at 2.6 A resolution and comparison with bovine phospholipase A2. (1983) (200)
- Active site and catalytic mechanism of phospholipase A2 (1981) (197)
- The structure of papain. (1971) (197)
- Molecular detection of genomic regions associated with grain yield and yield-related components in an elite bread wheat cross evaluated under irrigated and rainfed conditions (2009) (185)
- The heat shock factor family from Triticum aestivum in response to heat and other major abiotic stresses and their role in regulation of heat shock protein genes (2013) (174)
- Comparison of the three-dimensional protein and nucleotide structure of the FAD-binding domain of p-hydroxybenzoate hydroxylase with the FAD- as well as NADPH-binding domains of glutathione reductase. (1983) (173)
- Crystal structure of the p-hydroxybenzoate hydroxylase-substrate complex refined at 1.9 A resolution. Analysis of the enzyme-substrate and enzyme-product complexes. (1989) (172)
- Crystal structure of p-hydroxybenzoate hydroxylase. (1979) (163)
- The fungal hydrophobin Sc3p self-assembles at the surface of aerial hyphae as a protein membrane constituting the hydrophobic rodlet layer. (1994) (156)
- The toxin-agglutinin fold. A new group of small protein structures organized around a four-disulfide core. (1980) (140)
- Relation between the solubility of proteins in aqueous solutions and the second virial coefficient of the solution (1999) (137)
- Three-dimensional structure and disulfide bond connections in bovine pancreatic phospholipase A2. (1978) (131)
- TaHsfA6f is a transcriptional activator that regulates a suite of heat stress protection genes in wheat (Triticum aestivum L.) including previously unknown Hsf targets (2014) (120)
- Structure of quinoprotein methylamine dehydrogenase at 2.25 A resolution. (1989) (118)
- Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate. (1988) (101)
- X-ray structure of lipoamide dehydrogenase from Azotobacter vinelandii determined by a combination of molecular and isomorphous replacement techniques. (1989) (94)
- Enhanced activity and altered specificity of phospholipase A2 by deletion of a surface loop. (1989) (89)
- Understanding protein crystallization on the basis of the phase diagram (1999) (86)
- Subunit composition, x-ray diffraction, amino acid analysis and oxygen binding behaviour of Panulirus interruptus hemocyanin. (1975) (83)
- Subtilisin Novo. The three-dimensional structure and its comparison with subtilisin BPN'. (1972) (82)
- Identifications of two different mechanisms for sorghum midge resistance through QTL mapping (2003) (81)
- Crystal structure of bovine pancreatic phospholipase A2 covalently inhibited by p-bromo-phenacyl-bromide. (1988) (76)
- Heat shock factor C2a serves as a proactive mechanism for heat protection in developing grains in wheat via an ABA-mediated regulatory pathway. (2018) (76)
- Resistance gene analogues in sugarcane and sorghum and their association with quantitative trait loci for rust resistance. (2005) (74)
- Structure of porcine pancreatic prephospholipase A2 (1976) (73)
- Role of the N-terminus in the interaction of pancreatic phospholipase A2 with aggregated substrates. Properties and crystal structure of transaminated phospholipase A2. (1983) (70)
- TaMYB13 is a transcriptional activator of fructosyltransferase genes involved in β-2,6-linked fructan synthesis in wheat. (2011) (69)
- p‐Hydroxybenzoate Hydroxylase from Pseudomonas fluorescens (1983) (58)
- The protein-water phase diagram and the growth of protein crystals from aqueous solution (1998) (55)
- Crystallography in Molecular Biology (1987) (51)
- The Interface between a Protein Crystal and an Aqueous Solution and Its Effects on Nucleation and Crystal Growth (2000) (50)
- Primary and tertiary structure studies of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens. Isolation and alignment of the CNBr peptides; interactions of the protein with flavin adenine dinucleotide. (2005) (49)
- Analysis of the active site of the flavoprotein p-hydroxybenzoate hydroxylase and some ideas with respect to its reaction mechanism. (1990) (49)
- A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo. (1972) (47)
- TaMYB13-1, a R2R3 MYB transcription factor, regulates the fructan synthetic pathway and contributes to enhanced fructan accumulation in bread wheat (2013) (45)
- Molecular characterization of the waxy locus in sorghum. (2008) (45)
- Structure of the papain molecule (1970) (39)
- Crystallogenesis of biological macromolecules. Biological, microgravity and other physico-chemical aspects (1995) (39)
- IV. Cysteine proteinases (1970) (37)
- Purification, crystallization and preliminary X-ray investigation of quinoprotein methylamine dehydrogenase from Thiobacillus versutus. (1986) (37)
- THE STRUCTURE OF BOVINE PANCREATIC PROPHOSPHOLIPASE A2 AT 3.0 A RESOLUTION (1981) (35)
- The influence of purification and protein heterogeneity on the crystallization of p-hydroxybenzoate hydroxylase. (1989) (34)
- Heat-labile enterotoxin of Escherichia coli. Characterization of different crystal forms. (1985) (34)
- Genetic and expression profiling in sugarcane (2001) (34)
- Abiotic stress upregulated TaZFP34 represses the expression of type-B response regulator and SHY2 genes and enhances root to shoot ratio in wheat. (2016) (32)
- 13 Papain, X-Ray Structure (1971) (30)
- Engineering a Diverse Ligase Toolbox for Peptide Segment Condensation (2016) (30)
- Enzymes : structure and function (1972) (29)
- The crystal structure of papain: II. A three-dimensional fourier synthesis at 4.5 Å resolution (1967) (29)
- Structure of an engineered porcine phospholipase A2 with enhanced activity at 2.1 A resolution. Comparison with the wild-type porcine and Crotalus atrox phospholipase A2. (1990) (29)
- Dissecting the molecular basis of the contribution of source strength to high fructan accumulation in wheat (2012) (28)
- Crystal structure of the reduced form of p‐ hydroxybenzoate hydroxylase refined at 2.3 Å resolution (1992) (28)
- Homologues of the maize rust resistance gene Rp1-D are genetically associated with a major rust resistance QTL in sorghum (2004) (27)
- PROTEIN CRYSTALS AND THEIR STABILITY (1992) (26)
- The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation. (1989) (24)
- The interaction energy between two protein molecules related to physical properties of their solution and their crystals and implications for crystal growth (1995) (24)
- The crystal structure of papain C (1962) (23)
- William and Lawrence Bragg, father and son: The most extraordinary collaboration in science (2008) (22)
- Pancreatic colipase: crystallographic and biochemical aspects. (1982) (22)
- Nucleation in protein crystallization. (1998) (21)
- A 200 bp region of the pea ENOD12 promoter is sufficient for nodule-specific and Nod factor induced expression (1995) (21)
- A comparison of crystallographic data of the subtilopeptidases B and C. (1967) (21)
- The structure of neurophysin. (1981) (21)
- Molecular modeling reveals the possible importance of a carbonyl oxygen binding pocket for the catalytic mechanism of p-hydroxybenzoate hydroxylase. (1988) (18)
- Chemoenzymatic Synthesis of an Unnatural Deazaflavin Cofactor That Can Fuel F420-Dependent Enzymes (2019) (17)
- Crystallization and preliminary x-ray investigation of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens. (1975) (17)
- Identification of DNA markers linked to agronomic traits in sugarcane in Australia. (2001) (16)
- Structure determination of quinoprotein methylamine dehydrogenase from Thiobacillus versutus. (1990) (16)
- Crystallographic data for rhodanese from bovine liver. (1971) (16)
- A strong root-specific expression system for stable transgene expression in bread wheat (2016) (16)
- Crystal structure of a porcine pancreatic phospholipase A2 mutant. A large conformational change caused by the F63V point mutation. (1993) (15)
- Effect of molecular anisotropy on the nucleation of lysozyme (2003) (14)
- Characterization of the soybean gene GmENOD40-2 (1995) (14)
- STRUCTURE OF BOVINE PANCREATIC PHOSPHOLIPASE A2 AT 1.7 ANGSTROMS RESOLUTION (1981) (13)
- Crystallization and preliminary X-ray investigation of lipoamide dehydrogenase from Azotobacter vinelandii. (1983) (13)
- Site-directed mutagenesis and X-ray crystallography of two phospholipase A2 mutants: Y52F and Y73F. (1992) (12)
- On the crystal structure of guanidinium bromate (1953) (11)
- STRUCTURE OF RHODANESE AT 4A RESOLUTION CONFORMATION OF POLYPEPTIDE-CHAIN (1974) (11)
- The Three-Dimensional Structure of Papain (1970) (11)
- PROTEOLYTIC-ENZYMES - GENERAL FEATURES OF THEIR MODE OF ACTION (1980) (10)
- The Unit Cell of Mercuripapain Crystals (1959) (10)
- Papain in water-rich and in methanol-rich media; crystallization and conformation. (1968) (10)
- Direct sequencing of RAPD fragments using 3'-extended oligonucleotide primers and dye terminator cycle-sequencing. (1999) (9)
- Experiments in membrane protein crystallization (1988) (9)
- STRUCTURE OF PAPAIN REFINED AT 1.65 ANGSTROMS RESOLUTION (1986) (8)
- p-Hydroxybenzoate hydroxylase from Pseudomonas fluorescens. 2. Fitting of the amino-acid sequence to the tertiary structure. (1983) (8)
- X‐Ray Crystallography (2002) (6)
- Mesoscopic theories for protein crystal growth. (1994) (6)
- The nucleation of lysozyme from a fluctuation point of view (2005) (5)
- A Tailor-Made Deazaflavin-Mediated Recycling System for Artificial Nicotinamide Cofactor Biomimetics (2021) (5)
- An automatic integrating microdensitometer (1965) (4)
- The Theory of X-ray Diffraction by a Crystal (2007) (4)
- MECHANISM OF PAPAIN ACTION (1975) (4)
- Crystallizing a Protein (2007) (4)
- Microhydrodynamics simulation of protein crystallization. I. Static calculations. (1994) (4)
- Thermostable D-amino acid decarboxylases derived from Thermotoga maritima diaminopimelate decarboxylase (2021) (3)
- The molecular replacement method. A collection of papers on the use of non‐crystallographic symmetry edited by M. G. Rossmann (1974) (3)
- Crystal Growth of Biological Materials (1987) (2)
- An optimal strategy for X-ray data collection on macromolecular crystals with position-sensitive detectors (1994) (2)
- Introducing an Artificial Deazaflavin Cofactor in Escherichia coli and Saccharomyces cerevisiae (2022) (2)
- p-Hydroxybenzoate hydroxylase from Pseudomonas fluorescens (1984) (1)
- Structure and function of phospholipases: an X-ray study of prophospholipase A2. (1978) (1)
- The Solution of the Phase Problem by the Isomorphous Replacement Method (2007) (1)
- A strong root-specific expression system for stable transgene expression in bread wheat (2015) (1)
- Introduction to basic crystallography (2006) (1)
- Bovine Phospholipase A2 Crystals Soaked in 30% Methanol (1986) (1)
- IV. Cysteine proteinases. The structure of the papain molecule. (1970) (1)
- Natural Flavins: Occurrence, Role, and Noncanonical Chemistry (2021) (1)
- X-ray crystallographic studies on lipoamidehydrogenase from Azotobacter vinelandii (1984) (0)
- THE 3-DIMENSIONAL STRUCTURE OF PROTEOLYTIC-ENZYMES (1981) (0)
- A LARGE CONFORMATIONAL CHANGE IS FOUND IN THE CRYSTAL STRUCTURE OF THE PORCINE PANCREATIC PHOSPHOLIPASE A2 POINT MUTANT F63V (1993) (0)
- A multi-disciplinary study on p-hydroxybenzoate hydroxylase from P.fluorescens: molecular properties, three dimensional structure and amino acid sequence (1980) (0)
- Average Reflection Intensity and Distribution of Structure Factor Data (2007) (0)
- The Structure of p-Hydroxybenzoate Hydroxylase (2018) (0)
- University of Groningen Crystal Structure of Bovine Pancreatic Phospholipase A2 Covalently Inhibited by p-Bromo- phenacyl-bromide Renetseder, (2003) (0)
- The structure of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens (1982) (0)
- X-ray Sources and Detectors (2007) (0)
- STRUCTURAL DIFFERENCES IN CLOSELY RELATED PANCREATIC PHOSPHOLIPASES-A2 (1984) (0)
- Checking for Gross Errors and Estimating the Accuracy of the Structural Model (2007) (0)
- The structure and function of p-hydroxybenzoate hydroxylase (1982) (0)
- Inhibition, preleminary sequence and X-ray studies on p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens (1976) (0)
- The Combination of Phase Information (2007) (0)
- 3 DIMENSIONAL STRUCTURE OF BOVINE PANCREATIC PHOSPHOLIPASE A2 (1978) (0)
- Recipes for the protein crystallographer (1994) (0)
- Ralph W. G. Wyckoff, 1897-1994 (1995) (0)
- A milestone for macromolecular crystallography (1998) (0)
- Excelsin, edestin, and tobacco seed globulin crystals. Preparation, density, and X-ray measurements (2010) (0)
- The active site of phospholipase A2 (1984) (0)
- Towards a better understanding of disease resistance in sugarcane and sorghum (2003) (0)
- Promoter analysis of PsENOD12 in transgenic Vicia hirsuta nodules. (1994) (0)
- Special Forms of the Structure Factor (2007) (0)
- THE COVALENT AND THREE DIMENSIONAL STRUCTURE OF p-HYDROXYBENZOATE HYDROXYLASE FROM P. FLUORESCENS (1981) (0)
- Flavin-tag: A Facile Method for Site-Specific Labeling of Proteins with a Flavin Fluorophore. (2021) (0)
- PARA-HYDROXYBENZOATE HYDROXYLASE FROM PSEUDOMONAS FLUORESCENCE (1984) (0)
- Checklist for Adaptable Renovation (1996) (0)
- REFINEMENT OF THE CRYSTAL-STRUCTURE OF PAPAIN (1978) (0)
- FOP (2017) (0)
- X-ray Diffraction: Principles (2003) (0)
- THREE-DIMIENSIONAL SHAPE OF A MACROMOLECULE (2017) (0)
- X-ray crystallographic studies on lipoamide dehydrogenase from Azotobacter vinelandii (1984) (0)
- Modificatie van Tyr-38 in p-hydroxybenzoaat hydroxylase uit P. fluorescens. (1987) (0)
- Refinement of the Model Structure (2007) (0)
- R‐Factor (Crystallographic) (2002) (0)
- Dissecting the molecular basis of the contribution of source strength to high fructan accumulation in wheat (2012) (0)
- Table of contents (1989) (0)
- Crystallographic studies on the mechanism of hydroxybenzoate hydroxylase from Psudomonas fluorescens (1987) (0)
- Chemical modification of Tyr-38 in p-hydroxybenzoate hydroxylase: A probe for the elucidation of the NADPH binding site? (1987) (0)
- Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Configuration (2007) (0)
- University of Groningen Structure of Porcine Pancreatic Phospholipase A 2 at 2 . 6 Å Resolution and Comparison with Bovine Phospholipase (2018) (0)
- Multiple-Wavelength Anomalous Dispersion MAD (2002) (0)
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