Jan Karlseder
#53,405
Most Influential Person Now
Austrian molecular biologist
Jan Karlseder's AcademicInfluence.com Rankings
Jan Karlsederbiology Degrees
Biology
#2520
World Rank
#3987
Historical Rank
Molecular Biology
#1473
World Rank
#1500
Historical Rank
Genetics
#1440
World Rank
#1542
Historical Rank
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Biology
Jan Karlseder's Degrees
- PhD Molecular Biology University of Vienna
- Masters Biochemistry University of Vienna
Why Is Jan Karlseder Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jan Karlseder is an Austrian molecular biologist, a professor in the Molecular and Cellular Biology Laboratory, the Director of the Paul F. Glenn Center for Biology of Aging Research and the holder of the Donald and Darlene Shiley Chair at the Salk Institute for Biological Studies.
Jan Karlseder's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. (1999) (1131)
- Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication (2009) (903)
- Telomeres: protecting chromosomes against genome instability (2010) (832)
- Senescence Induced by Altered Telomere State, Not Telomere Loss (2002) (808)
- Defective Telomere Lagging Strand Synthesis in Cells Lacking WRN Helicase Activity (2004) (576)
- Replication and protection of telomeres (2007) (483)
- The Telomeric Protein TRF2 Binds the ATM Kinase and Can Inhibit the ATM-Dependent DNA Damage Response (2004) (401)
- DNA Ligase IV-Dependent NHEJ of Deprotected Mammalian Telomeres in G1 and G2 (2002) (392)
- The DNA Damage Machinery and Homologous Recombination Pathway Act Consecutively to Protect Human Telomeres (2006) (364)
- Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F (1996) (361)
- Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres (2010) (343)
- TERRA and hnRNPA1 Orchestrate an RPA-to-POT1 Switch on Telomeric Single-Stranded DNA (2010) (308)
- Functional human telomeres are recognized as DNA damage in G2 of the cell cycle. (2005) (301)
- Autophagic cell death restricts chromosomal instability during replicative crisis (2019) (242)
- Telomere dysfunction as a cause of genomic instability in Werner syndrome (2007) (230)
- Rapid induction of Alternative Lengthening of Telomeres by depletion of the histone chaperone ASF1 (2013) (202)
- Targeted Deletion Reveals an Essential Function for the Telomere Length Regulator Trf1 (2003) (190)
- Complex interactions between the DNA-damage response and mammalian telomeres (2015) (157)
- A Telomere Dependent DNA Damage Checkpoint Induced by Prolonged Mitotic Arrest (2012) (153)
- Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer (2011) (142)
- The telomere deprotection response is functionally distinct from the genomic DNA damage response. (2013) (138)
- The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures (2012) (134)
- DNA damage associated with mitosis and cytokinesis failure (2013) (133)
- C. elegans Telomeres Contain G-Strand and C-Strand Overhangs that Are Bound by Distinct Proteins (2008) (127)
- Regulation of DNA Repair pathway choice in S/G2 by the NHEJ inhibitor CYREN (2017) (122)
- TZAP: A telomere-associated protein involved in telomere length control (2017) (118)
- Patterns of dna amplification at band q13 of chromosome 11 in human breast cancer (1994) (111)
- Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly. (2012) (110)
- Drug resistance against gemcitabine and topotecan mediated by constitutive hsp70 overexpression in vitro: implication of quercetin as sensitiser in chemotherapy. (1996) (105)
- Telomere repeat binding factors: keeping the ends in check. (2003) (100)
- The great unravelling: chromatin as a modulator of the aging process. (2012) (96)
- Cell Death During Crisis Is Mediated by Mitotic Telomere Deprotection (2015) (94)
- The Adenovirus E1b55K/E4orf6 Complex Induces Degradation of the Bloom Helicase during Infection (2010) (80)
- A three-state model of telomere control over human proliferative boundaries. (2012) (79)
- HSP70 overexpression mediates the escape of a doxorubicin-induced G2 cell cycle arrest. (1996) (78)
- A balance between elongation and trimming regulates telomere stability in stem cells (2016) (76)
- Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance. (2011) (71)
- Correction: Uncoupling of Longevity and Telomere Length in C. elegans (2005) (68)
- Uncoupling of Longevity and Telomere Length in C. elegans (2005) (66)
- Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN (2017) (62)
- Telomeric armor: the layers of end protection (2009) (49)
- Impact papers on aging in 2009 (2010) (40)
- A genomics approach identifies senescence-specific gene expression regulation (2014) (39)
- alpha-Melanocyte stimulating hormone downregulates differentiation-driven heat shock protein 70 expression in keratinocytes. (1997) (34)
- Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection (2018) (28)
- Carboxy-terminal residues of mouse thymidine kinase are essential for rapid degradation in quiescent cells. (1996) (27)
- In situ detection of protein-DNA interactions in filamentous fungi by in vivo footprinting. (1998) (25)
- 5' C-rich telomeric overhangs are an outcome of rapid telomere truncation events. (2013) (21)
- Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans (2012) (21)
- Mammalian Rap1 widens its impact (2010) (18)
- A siRNA-Based Screen for Genes Involved in Chromosome End Protection (2011) (18)
- In the end, it's all structure. (2005) (17)
- ALT Telomeres Borrow from Meiosis to Get Moving (2014) (13)
- Impact papers on aging in 2009 - eScholarship (2010) (11)
- Moderate expression of TRF2 in the hematopoietic system increases development of large cell blastic T-cell lymphomas (2009) (10)
- Telomeric proteins: clearing the way for the replication fork (2006) (10)
- Telomeres and Cancer: Resolving the Paradox (2021) (8)
- Chromosome end protection becomes even more complex (2009) (8)
- The Adenovirus E 1 b 55 K / E 4 orf 6 Complex Induces Degradation of the Bloom Helicase during Infection (2011) (7)
- A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia (2020) (5)
- Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis (2023) (4)
- C. elegans survivors without telomerase (2013) (4)
- Identification of Syndecan-1 As a Key Dependency of Myeloid Leukemia Growth and Dissemination (2018) (3)
- Faculty Opinions recommendation of Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism. (2017) (2)
- Of wombats and whales: telomere tales in Madrid (2007) (2)
- Cellular versus Organismal Aging (2008) (1)
- Title Replication stress induces mitotic death through parallelpathways regulated by WAPL and telomere deprotection (2019) (1)
- Suppression of genomic instability by replicative senescence and crisis (2020) (1)
- Faculty Opinions recommendation of Loss of ATRX suppresses resolution of telomere cohesion to control recombination in ALT cancer cells. (2015) (1)
- Modern genome editing meets telomeres: the many functions of TPP1 (2014) (1)
- Faculty Opinions recommendation of Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle. (2017) (1)
- Faculty Opinions recommendation of BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage. (2021) (0)
- Faculty Opinions recommendation of L1 drives IFN in senescent cells and promotes age-associated inflammation. (2019) (0)
- Faculty of 1000 evaluation for Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway. (2018) (0)
- cycle-regulated transcription factor E2F. Interaction of Sp1 with the growth- and cell (2013) (0)
- Faculty Opinions recommendation of Mitotic progression following DNA damage enables pattern recognition within micronuclei. (2019) (0)
- Telomere Lagging Strand Synthesis Dysfunction in Cells Lacking WRN Helicase Activity (2004) (0)
- Faculty Opinions recommendation of CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle. (2019) (0)
- Faculty Opinions recommendation of Mitochondrial DNA stress signalling protects the nuclear genome. (2020) (0)
- Autophagic cell death restricts chromosomal instability during replicative crisis (2019) (0)
- Faculty Opinions recommendation of RAD51AP1 is an essential mediator of alternative lengthening of telomeres. (2019) (0)
- Faculty of 1000 evaluation for Cytoplasmic chromatin triggers inflammation in senescence and cancer. (2018) (0)
- Decision letter: Telomeric double-strand DNA-binding proteins DTN-1 and DTN-2 ensure germline immortality in Caenorhabditis elegans (2020) (0)
- Faculty Opinions recommendation of Break-induced telomere synthesis underlies alternative telomere maintenance. (2017) (0)
- Faculty Opinions recommendation of The evolution of metazoan shelterin. (2022) (0)
- Hyperextended telomeres promote formation of C-circle DNA in telomerase positive human cells. (2023) (0)
- Faculty Opinions recommendation of Mitohormesis in mice via sustained basal activation of mitochondrial and antioxidant signaling. (2019) (0)
- Faculty Opinions recommendation of Chromothripsis and kataegis induced by telomere crisis. (2018) (0)
- TRF2 regulates differential DNA damage response signaling from intermediate‐state and uncapped‐state telomeres (2012) (0)
- Faculty Opinions recommendation of RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops. (2020) (0)
- Hyperextended telomeres promote C-circle formation in telomerase positive human cells (2023) (0)
- TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX-deficient cells. (2023) (0)
- Faculty Opinions recommendation of Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin. (2020) (0)
- Decision letter: Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment (2019) (0)
- Faculty Opinions recommendation of TINF2 is a haploinsufficient tumor suppressor that limits telomere length. (0)
- Impact papers on aging in 2009 Citation (2022) (0)
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What Schools Are Affiliated With Jan Karlseder?
Jan Karlseder is affiliated with the following schools:
