Jan Tytgat

Jan Tytgat's AcademicInfluence.com Rankings

Jan Tytgat

Chemistry

#3843

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#4886

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Organic Chemistry

#605

World Rank

#696

Historical Rank

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Chemistry

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Jan Tytgat's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs (1992) (1091)
Scorpion toxins specific for Na+-channels. (1999) (629)
A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies. (1999) (381)
Recycling rechargeable lithium ion batteries: Critical analysis of natural resource savings (2010) (285)
An overview of toxins and genes from the venom of the Asian scorpion Buthus martensi Karsch. (2002) (260)
Functional Heteromerization of HCN1 and HCN2 Pacemaker Channels* (2001) (221)
Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels (2011) (197)
Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. (2002) (173)
Four Novel Tarantula Toxins as Selective Modulators of Voltage-Gated Sodium Channel Subtypes (2006) (147)
Voltage-gated sodium channel modulation by scorpion α-toxins (2007) (144)
Evolutionary origin of inhibitor cystine knot peptides (2003) (144)
Evidence for cooperative interactions in potassium channel gating (1992) (138)
Conotoxins Targeting Nicotinic Acetylcholine Receptors: An Overview (2014) (128)
kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity. (2002) (123)
Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity (2017) (122)
Phylogenetic distribution, functional epitopes and evolution of the CSαβ superfamily (2005) (113)
The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control. (2007) (112)
The ATP-Gated P2X1 Ion Channel Acts as a Positive Regulator of Platelet Responses to Collagen (2001) (102)
A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties. (2011) (101)
Expression of Human pICln and ClC-6 in Xenopus Oocytes Induces an Identical Endogenous Chloride Conductance* (1997) (100)
Multisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia chrysanthemi Ligand-gated Ion Channel (ELIC)* (2013) (94)
Sea anemone venom as a source of insecticidal peptides acting on voltage-gated Na+ channels. (2007) (93)
Adaptive Evolution of Scorpion Sodium Channel Toxins (2004) (80)
A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins (2012) (80)
Effect of fluoxetine on a neuronal, voltage‐dependent potassium channel (Kv1.1) (1997) (79)
Function and solution structure of hainantoxin‐I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana1 (2003) (78)
Potent Modulation of the Voltage-Gated Sodium Channel Nav1.7 by OD1, a Toxin from the Scorpion Odonthobuthus doriae (2006) (77)
Cytolytic and K+ channel blocking activities of β-KTx and scorpine-like peptides purified from scorpion venoms (2007) (77)
The chloride current induced by expression of the protein pICln in Xenopus oocytes differs from the endogenous volume‐sensitive chloride current. (1996) (75)
The scorpine family of defensins: gene structure, alternative polyadenylation and fold recognition (2004) (74)
An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis. (2005) (74)
Animal peptides targeting voltage-activated sodium channels. (2008) (74)
Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels. (2008) (73)
Jingzhaotoxin-I, a Novel Spider Neurotoxin Preferentially Inhibiting Cardiac Sodium Channel Inactivation* (2005) (72)
Jellyfish and other cnidarian envenomations cause pain by affecting TRPV1 channels (2006) (72)
Targeting Cannabinoid Receptors: Current Status and Prospects of Natural Products (2020) (71)
How to isolate cardiac myocytes. (1994) (71)
A Novel Conotoxin from Conus betulinus, κ-BtX, Unique in Cysteine Pattern and in Function as a Specific BK Channel Modulator* (2003) (70)
Flunarizine inhibits a high-threshold inactivating calcium channel (N-type) in isolated hippocampal neurons (1991) (59)
Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels. (2002) (57)
The evaluation of the applicability of a high pH mobile phase in ultrahigh performance liquid chromatography tandem mass spectrometry analysis of benzodiazepines and benzodiazepine-like hypnotics in urine and blood. (2012) (57)
Modulation of the T-type cardiac Ca channel by changes in proton concentration (1990) (57)
Crotamine Pharmacology Revisited: Novel Insights Based on the Inhibition of KV Channels (2012) (57)
The α-Dendrotoxin Footprint on a Mammalian Potassium Channel (*) (1995) (56)
A novel sea anemone peptide that inhibits acid-sensing ion channels (2014) (55)
Crystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding Protein* (2010) (54)
OD1, the first toxin isolated from the venom of the scorpion Odonthobuthus doriae active on voltage‐gated Na+ channels (2005) (54)
Molecular diversity of the telson and venom components from Pandinus cavimanus (Scorpionidae Latreille 1802): Transcriptome, venomics and function (2012) (53)
Importance of the conserved aromatic residues in the scorpion alpha-like toxin BmK M1: the hydrophobic surface region revisited. (2003) (53)
Experimental conversion of a defensin into a neurotoxin: implications for origin of toxic function. (2014) (53)
A novel conotoxin inhibiting vertebrate voltage-sensitive potassium channels. (2003) (53)
The sea anemone Bunodosoma granulifera contains surprisingly efficacious and potent insect‐selective toxins (2002) (49)
Evolutionary Diversification of Mesobuthus α-Scorpion Toxins Affecting Sodium Channels* (2011) (47)
Transgenerational epigenetic effects from male exposure to endocrine-disrupting compounds: a systematic review on research in mammals (2020) (47)
Molecular Diversity and Functional Evolution of Scorpion Potassium Channel Toxins* (2010) (47)
MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity. (2010) (46)
Voltage-gated sodium channel modulation by scorpion alpha-toxins. (2007) (45)
Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels. (2003) (44)
Differential effects of verapamil and flunarizine on cardiac L-type and T-type Ca channels (1988) (44)
Kunitz-Type Peptide HCRG21 from the Sea Anemone Heteractis crispa Is a Full Antagonist of the TRPV1 Receptor (2016) (44)
A novel µ‐conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors (2012) (43)
Development and validation of a fast ionic liquid-based dispersive liquid-liquid microextraction procedure combined with LC-MS/MS analysis for the quantification of benzodiazepines and benzodiazepine-like hypnotics in whole blood. (2017) (42)
A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol (2009) (42)
TRPV1 as a key determinant in ciguatera and neurotoxic shellfish poisoning. (2007) (41)
Preparation of longitudinal sections of hair samples for the analysis of cocaine by MALDI-MS/MS and TOF-SIMS imaging. (2015) (41)
Morphine-6beta-glucuronide and morphine-3-glucuronide, opioid receptor agonists with different potencies. (2001) (41)
BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currents. (2004) (40)
Determination of species-specific components in the venom of Parabuthus scorpions from southern Africa using matrix-assisted laser desorption time-of-flight mass spectrometry. (2002) (40)
Molecular basis of the mammalian potency of the scorpion α‐like toxin, BmK M1 (2005) (39)
Mechanism of cardiac T-type Ca channel blockade by amiloride. (1990) (39)
In the picture: disulfide-poor conopeptides, a class of pharmacologically interesting compounds (2016) (39)
Solution Structure and Alanine Scan of a Spider Toxin That Affects the Activation of Mammalian Voltage-gated Sodium Channels* (2007) (38)
Toxins in Drug Discovery and Pharmacology (2018) (38)
Venom components from Citharischius crawshayi spider (Family Theraphosidae): exploring transcriptome, venomics, and function (2010) (38)
The Search for a Volatile Human Specific Marker in the Decomposition Process (2015) (38)
Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom (2012) (37)
Biochemical and Electrophysiological Characterization of Two Sea Anemone Type 1 Potassium Toxins from a Geographically Distant Population of Bunodosoma caissarum (2013) (37)
Fast and easy extraction of antidepressants from whole blood using ionic liquids as extraction solvent. (2018) (37)
BmBKTx1, a Novel Ca2+-activated K+ Channel Blocker Purified from the Asian Scorpion Buthus martensi Karsch* (2004) (37)
A novel class of pore-forming peptides in the venom of parabuthus schlechteri Purcell (scorpions: buthidae) (2000) (37)
BjαIT: a novel scorpion α-toxin selective for insects—unique pharmacological tool (2005) (36)
Norpropoxyphene-induced cardiotoxicity is associated with changes in ion-selectivity and gating of HERG currents. (1999) (36)
Turret and pore block of K+ channels: what is the difference? (2003) (36)
Purification and partial characterization of a ‘short' insectotoxin‐like peptide from the venom of the scorpion Parabuthus schlechteri (1998) (36)
Development and validation of a sensitive UPLC-MS/MS method for the analysis of narcotic analgesics in urine and whole blood in forensic context. (2012) (36)
A potent potassium channel blocker from Mesobuthus eupeus scorpion venom. (2010) (35)
The dual modulation of GIRK1/GIRK2 channels by opioid receptor ligands. (1999) (35)
Structural basis for the voltage-gated Na+ channel selectivity of the scorpion alpha-like toxin BmK M1. (2005) (35)
The Kunitz-Type Protein ShPI-1 Inhibits Serine Proteases and Voltage-Gated Potassium Channels (2016) (35)
Importance of position 8 in μ‐conotoxin KIIIA for voltage‐gated sodium channel selectivity (2011) (35)
Evolutionary trace analysis of scorpion toxins specific for K‐channels (2003) (35)
Development and validation of a new TD-GC/MS method and its applicability in the search for human and animal decomposition products (2014) (34)
Electrophysiological Characterization of Ts6 and Ts7, K+ Channel Toxins Isolated through an Improved Tityus serrulatus Venom Purification Procedure (2014) (34)
The use of presumptive color tests for new psychoactive substances. (2016) (34)
Phylogenetic distribution, functional epitopes and evolution of the CSalphabeta superfamily. (2005) (34)
Characterization of two Bunodosoma granulifera toxins active on cardiac sodium channels (2001) (34)
Solution structure of two insect‐specific spider toxins and their pharmacological interaction with the insect voltage‐gated Na+ channel (2005) (33)
Identification, structural and pharmacological characterization of τ-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor. (2013) (33)
BcsTx3 is a founder of a novel sea anemone toxin family of potassium channel blocker (2013) (33)
Pursuing the voltage sensor of a voltage-gated mammalian potassium channel. (1993) (33)
A gamut of undiscovered electrophysiological effects produced by Tityus serrulatus toxin 1 on NaV-type isoforms (2015) (33)
The use of pesticides in Belgian illicit indoor cannabis plantations. (2017) (33)
The birth and death of toxins with distinct functions: a case study in the sea anemone Nematostella. (2019) (33)
Consequences of Decontamination Procedures in Forensic Hair Analysis Using Metal-Assisted Secondary Ion Mass Spectrometry Analysis. (2016) (33)
Phoneutria nigriventer venom: A pharmacological treasure (2018) (32)
A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new α‐KTX subfamily (2006) (32)
Assignment of voltage-gated potassium channel blocking activity to κ-ktx1.3, a non-toxic homologue of κ-hefutoxin-1, from Heterometrus spinifer venom (2005) (32)
Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1 (2015) (32)
PnPP-19, a Synthetic and Nontoxic Peptide Designed from a Phoneutria nigriventer Toxin, Potentiates Erectile Function via NO/cGMP. (2015) (32)
Development and validation of a sensitive ultra performance liquid chromatography tandem mass spectrometry method for the analysis of fentanyl and its major metabolite norfentanyl in urine and whole blood in forensic context. (2010) (32)
OdK2, a Kv1.3 channel-selective toxin from the venom of the Iranian scorpion Odonthobuthus doriae. (2008) (31)
Multiple actions of φ-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins (2013) (31)
APETx4, a Novel Sea Anemone Toxin and a Modulator of the Cancer-Relevant Potassium Channel KV10.1 (2017) (31)
Differential effects of five 'classical' scorpion beta-toxins on rNav1.2a and DmNav1 provide clues on species-selectivity. (2007) (31)
The depressant scorpion neurotoxin LqqIT2 selectively modulates the insect voltage-gated sodium channel. (2005) (30)
Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2. (2009) (30)
Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease (2017) (30)
The T-type Ca channel in guinea-pig ventricular myocytes is insensitive to isoproterenol (1988) (30)
Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): the first member of a new κ-KTX subfamily. (2012) (30)
The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels (2016) (30)
Evolutionary epitopes of Hsp90 and p23: implications for their interaction (2004) (30)
Synthesis, Solution Structure, and Phylum Selectivity of a Spider δ-Toxin That Slows Inactivation of Specific Voltage-gated Sodium Channel Subtypes* (2009) (29)
Purification and characterization of Ts15, the first member of a new α-KTX subfamily from the venom of the Brazilian scorpion Tityus serrulatus. (2011) (29)
Modular Organization of α-Toxins from Scorpion Venom Mirrors Domain Structure of Their Targets, Sodium Channels* (2013) (29)
Chronic administration of anticholinergics in rats induces a shift from muscarinic to purinergic transmission in the bladder wall. (2013) (29)
The new kappa-KTx 2.5 from the scorpion Opisthacanthus cayaporum (2011) (29)
Roles of disulfide bridges in scorpion toxin BmK M1 analyzed by mutagenesis. (2002) (29)
Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity. (2000) (29)
Voltage‐gated sodium channel isoform‐specific effects of pompilidotoxins (2010) (29)
Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus. (2004) (29)
Electrophysiological characterization of BmK M1, an α‐like toxin from Buthus martensi Karsch venom (2001) (29)
Detection of 2-amino-5-chloropyridine in urine as a parameter of zopiclone (Imovane) intake using HPLC with diode array detection. (1997) (28)
PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold (2018) (28)
A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes. (2008) (28)
Unique Bell-shaped Voltage-dependent Modulation of Na+ Channel Gating by Novel Insect-selective Toxins from the Spider Agelena orientalis* (2010) (27)
An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera (2008) (27)
Cardiac channelopathy causing sudden death as revealed by molecular autopsy (2012) (27)
Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels (2004) (27)
Comparison and characterization of the venoms of three Parabuthus scorpion species occurring in southern Africa. (1998) (27)
Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine (2016) (27)
OsK2, a new selective inhibitor of Kv1.2 potassium channels purified from the venom of the scorpion Orthochirus scrobiculosus. (2001) (27)
Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom. (2002) (26)
Novel conopeptides of the I-superfamily occur in several clades of cone snails. (2004) (26)
Characterization of scorpion alpha-like toxin group using two new toxins from the scorpion Leiurus quinquestriatus hebraeus. (2002) (26)
Functional Heteromerization of HCN 1 and HCN 2 Pacemaker Channels (2001) (25)
Investigating possible biological targets of Bj-CRP, the first cysteine-rich secretory protein (CRISP) isolated from Bothrops jararaca snake venom. (2017) (25)
An allosteric binding site of the α7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein (2017) (25)
The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae (2006) (25)
Fluorescent protein-scorpion toxin chimera is a convenient molecular tool for studies of potassium channels (2016) (25)
Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific. (1997) (25)
Design of Bioactive Peptides from Naturally Occurring μ-Conotoxin Structures* (2012) (25)
Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels (2015) (25)
A Subfamily of Acidic α-K+ Toxins* (2004) (24)
The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state (2013) (24)
Reversal of rectification and alteration of selectivity and pharmacology in a mammalian Kv1.1 potassium channel by deletion of domains S1 to S4. (1994) (24)
Mechanism of L- and T-type Ca2+ channel blockade by flunarizine in ventricular myocytes of the guinea-pig. (1996) (24)
Agonistic and antagonistic effect of R56865 on the Na+ channel in cardiac cells. (1991) (24)
Anise oil as para-methoxyamphetamine (PMA) precursor. (2003) (24)
Hydrogen peroxide reactions on cocaine in hair using imaging mass spectrometry. (2014) (24)
Revealing the Function and the Structural Model of Ts4: Insights into the “Non-Toxic” Toxin from Tityus serrulatus Venom (2015) (23)
Antimicrobial peptides from scorpion venom induce Ca(2+) signaling in HL-60 cells. (2003) (23)
The proteomic profile of Stichodactyla duerdeni secretion reveals the presence of a novel O-linked glycopeptide. (2013) (23)
Atypical Reactive Center Kunitz-Type Inhibitor from the Sea Anemone Heteractis crispa (2012) (23)
New "Birtoxin analogs" from Androctonus australis venom. (2005) (23)
Two recombinant α-like scorpion toxins from Mesobuthus eupeus with differential affinity toward insect and mammalian Na(+) channels. (2013) (23)
Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes (2018) (23)
The Mediterranean scorpion Mesobuthus gibbosus (Scorpiones, Buthidae): transcriptome analysis and organization of the genome encoding chlorotoxin-like peptides (2014) (23)
A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K+ channels. (2008) (22)
Electrophysiological characterization of the first Tityus serrulatus alpha-like toxin, Ts5: Evidence of a pro-inflammatory toxin on macrophages. (2015) (22)
Changes in GIRK1/GIRK2 deactivation kinetics and basal activity in the presence and absence of RGS4. (2000) (22)
Differential effects of the recombinant toxin PnTx4(5-5) from the spider Phoneutria nigriventer on mammalian and insect sodium channels. (2016) (22)
The recycling efficiency of Li-ion EV batteries according to the European Commission regulation, and the relation with the end-of-life vehicles directive recycling rate (2013) (22)
Gi- and Gs-coupled receptors up-regulate the cAMP cascade to modulate HCN2, but not HCN1 pacemaker channels (2001) (22)
Differential electrophysiology of repolarisation from clone to clinic. (1997) (22)
Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins (2016) (22)
Novel potassium channel blocker venom peptides from Mesobuthus gibbosus (Scorpiones: Buthidae). (2012) (22)
Structural Similarity between Defense Peptide from Wheat and Scorpion Neurotoxin Permits Rational Functional Design* (2014) (22)
Isolation and characterization of Ts19 Fragment II, a new long-chain potassium channel toxin from Tityus serrulatus venom (2016) (21)
Structure-Function Elucidation of a New α-Conotoxin, Lo1a, from Conus longurionis (2013) (21)
Subtype specificity interaction of bactridines with mammalian, insect and bacterial sodium channels under voltage clamp conditions (2012) (21)
The poison Dart frog's batrachotoxin modulates Nav1.8 (2004) (20)
Differential ion current activation by human 5-HT1A receptors in Xenopus oocytes: Evidence for agonist-directed trafficking of receptor signalling (2005) (20)
Serrumab: A novel human single chain-fragment antibody with multiple scorpion toxin-neutralizing capacities (2014) (20)
Target-Driven Positive Selection at Hot Spots of Scorpion Toxins Uncovers Their Potential in Design of Insecticides. (2016) (20)
Discovery of a new subclass of α-conotoxins in the venom of Conus australis. (2014) (20)
Isolation and characterization of two novel scorpion toxins: The alpha-toxin-like CeII8, specific for Na(v)1.7 channels and the classical anti-mammalian CeII9, specific for Na(v)1.4 channels. (2010) (20)
Where cone snails and spiders meet: design of small cyclic sodium‐channel inhibitors (2018) (20)
A combined study of sodium current and T-type calcium current in isolated cardiac cells (1990) (19)
Characterization of Na(+) currents in isolated dorsal unpaired median neurons of Locusta migratoria and effect of the alpha-like scorpion toxin BmK M1. (2003) (19)
Molecular divergence of two orthologous scorpion toxins affecting potassium channels. (2011) (19)
A ‘conovenomic’ analysis of the milked venom from the mollusk-hunting cone snail Conus textile—The pharmacological importance of post-translational modifications (2013) (18)
Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel KV10.1 (2017) (18)
Ts8 scorpion toxin inhibits the Kv4.2 channel and produces nociception in vivo. (2016) (18)
Inhibitory effect of the recombinant Phoneutria nigriventer Tx1 toxin on voltage-gated sodium channels. (2012) (18)
Time-dependent VOC-profile of decomposed human and animal remains in laboratory environment. (2016) (18)
Peptide ion channel toxins from the bootlace worm, the longest animal on Earth (2018) (18)
Evaluation of 11 ionic liquids as potential extraction solvents for benzodiazepines from whole blood using liquid-liquid microextraction combined with LC-MS/MS. (2018) (18)
Biochemical characterization of cysteine-rich peptides from Oxyopes sp. venom that block calcium ion channels. (2008) (17)
Drosotoxin, a selective inhibitor of tetrodotoxin-resistant sodium channels. (2010) (17)
Modulation of cardiac Na channels by angiotensin II. (1989) (17)
Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities (2020) (17)
Effect of lanthanum on voltage-dependent gating of a cloned mammalian neuronal potassium channel (1997) (17)
The role of the hydrophilic Asn230 residue of the μ‐opioid receptor in the potency of various opioid agonists (2001) (17)
Trancriptomic approach reveals the molecular diversity of Hottentotta conspersus (Buthidae) venom. (2015) (16)
Molecular basis of the mammalian potency of the scorpion alpha-like toxin, BmK M1. (2005) (16)
Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK (2018) (16)
Phyla- and Subtype-Selectivity of CgNa, a Na+ Channel Toxin from the Venom of the Giant Caribbean Sea Anemone Condylactis Gigantea (2010) (16)
Ligand- and Structure-Based Virtual Screening for Clathrodin-Derived Human Voltage-Gated Sodium Channel Modulators (2013) (16)
KV1.2 channel-specific blocker from Mesobuthus eupeus scorpion venom: Structural basis of selectivity (2018) (16)
Kunitz-Type Peptides from the Sea Anemone Heteractis crispa Demonstrate Potassium Channel Blocking and Anti-Inflammatory Activities (2020) (16)
Expanding the pharmacological profile of κ-hefutoxin 1 and analogues: A focus on the inhibitory effect on the oncogenic channel Kv10.1 (2017) (16)
BjalphaIT: a novel scorpion alpha-toxin selective for insects--unique pharmacological tool. (2005) (16)
Two novel sodium channel inhibitors from Heriaeus melloteei spider venom differentially interacting with mammalian channel's isoforms. (2008) (15)
Caterpillar Venom: A Health Hazard of the 21st Century (2020) (15)
Immunosuppressive evidence of Tityus serrulatus toxins Ts6 and Ts15: insights of a novel K+ channel pattern in T cells (2016) (15)
Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators. (2014) (15)
Discovery of KV1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges (2021) (15)
Structure-function study of a chlorotoxin-chimer and its activity on Kv1.3 channels. (2004) (15)
Chemical Synthesis, Proper Folding, Nav Channel Selectivity Profile and Analgesic Properties of the Spider Peptide Phlotoxin 1 (2019) (14)
The Peptide PnPP-19, a Spider Toxin Derivative, Activates μ-Opioid Receptors and Modulates Calcium Channels (2018) (14)
Venomous Secretions from Marine Snails of the Terebridae Family Target Acetylcholine Receptors (2013) (14)
Astemizole analogues with reduced hERG inhibition as potent antimalarial compounds. (2017) (14)
Identification, chemical synthesis, structure, and function of a new KV1 channel blocking peptide from Oulactis sp. (2018) (14)
A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins. (2019) (14)
Modulation of voltage-gated Na+ and K+ channels by pumiliotoxin 251D: a "joint venture" alkaloid from arthropods and amphibians. (2008) (14)
Pc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivity (2012) (14)
Synthesis, folding, structure and activity of a predicted peptide from the sea anemone Oulactis sp. with an ShKT fold (2018) (14)
Importance of the Conserved Aromatic Residues in the Scorpion α-Like Toxin BmK M1 (2003) (13)
Serine 329 of the μ-Opioid Receptor Interacts Differently with Agonists (2003) (13)
An improved fractionation and fast screening method for the identification of new and selective neurotoxins (1996) (13)
Overcoming challenges of HERG potassium channel liability through rational design: Eag1 inhibitors for cancer treatment (2021) (13)
Panusin represents a new family of &bgr;‐defensin‐like peptides in invertebrates (2017) (13)
δ-Conotoxins Synthesized Using an Acid-cleavable Solubility Tag Approach Reveal Key Structural Determinants for NaV Subtype Selectivity* (2014) (13)
New Insights into the Type II Toxins from the Sea Anemone Heteractis crispa (2020) (13)
Partial transcriptomic profiling of toxins from the venom gland of the scorpion Parabuthus stridulus. (2014) (13)
A new multigene HCIQ subfamily from the sea anemone Heteractis crispa encodes Kunitz-peptides exhibiting neuroprotective activity against 6-hydroxydopamine (2020) (13)
Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis (2013) (12)
Do voltage‐gated Kv1.1 and inward rectifier Kir2.1 potassium channels form heteromultimers? (1996) (12)
Determination of simmondsins and simmondsin ferulates in jojoba meal and feed by high-performance liquid chromatography (1996) (12)
Action of Clathrodin and Analogues on Voltage-Gated Sodium Channels (2014) (12)
Synthesis and characterization of amino acid deletion analogs of κ-hefutoxin 1, a scorpion toxin on potassium channels. (2013) (12)
Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors (2016) (12)
Structure of Membrane-active Toxin from Crab Spider Heriaeus melloteei Suggests Parallel Evolution of Sodium Channel Gating Modifiers in Araneomorphae and Mygalomorphae* (2014) (12)
Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. (2017) (11)
Neurotoxin Merging: A Strategy Deployed by the Venom of the Spider Cupiennius salei to Potentiate Toxicity on Insects (2020) (11)
Microextractions in forensic toxicology: The potential role of ionic liquids (2019) (11)
A Venomics approach coupled to high-throughput toxin production strategies identifies the first venom-derived melanocortin receptor agonists. (2020) (11)
Macrophage alteration induced by inflammatory toxins isolated from Tityus discrepans scorpion venom. The role of Na(+)/Ca(2+) exchangers. (2014) (11)
How a Scorpion Toxin Selectively Captures a Prey Sodium Channel: the Molecular and Evolutionary Basis Uncovered. (2020) (11)
Drug- and mutagenesis-induced changes in the selectivity filter of a cardiac two-pore background K+ channel. (2003) (11)
TRPV1 Channel as New Target for Marine Toxins: Example of Gigantoxin I, a Sea Anemone Toxin Acting Via Modulation of the PLA2 Pathway. (2011) (11)
High Affinity Scorpion Toxins for Studying Potassium and Sodium Channels (2001) (11)
Magnificamide, a β-Defensin-Like Peptide from the Mucus of the Sea Anemone Heteractis magnifica, Is a Strong Inhibitor of Mammalian α-Amylases (2019) (11)
Venom characterization of the bark scorpion Centruroides edwardsii (Gervais 1843): Composition, biochemical activities and in vivo toxicity for potential prey. (2019) (11)
Antiprotozoan lead discovery by aligning dry and wet screening: prediction, synthesis, and biological assay of novel quinoxalinones. (2014) (11)
Structure-Function Elucidation of a New α-Conotoxin, MilIA, from Conus milneedwardsi (2019) (11)
Novel Conopeptides of Largely Unexplored Indo Pacific Conus sp. (2016) (11)
Development of a stereospecific radioimmunoassay for the analysis of zopiclone and metabolites in urine. (1996) (11)
Evidence for a function‐specific mutation in the neurotoxin, parabutoxin 3 (2003) (10)
AbeTx1 Is a Novel Sea Anemone Toxin with a Dual Mechanism of Action on Shaker-Type K+ Channels Activation (2018) (10)
Expression, renaturation and functional analysis of an excitatory insect-specific toxin from scorpion Buthus martensii Karsch. (2005) (10)
Toxin bioportides: exploring toxin biological activity and multifunctionality (2017) (10)
Cannabinoid mimics in chocolate utilized as an argument in court (2000) (10)
Sea Anemone Kunitz-Type Peptides Demonstrate Neuroprotective Activity in the 6-Hydroxydopamine Induced Neurotoxicity Model (2021) (10)
Assignment of voltage-gated potassium channel blocking activity to kappa-KTx1.3, a non-toxic homologue of kappa-hefutoxin-1, from Heterometrus spinifer venom. (2005) (10)
New polypeptide components purified from mamba venom (2001) (10)
κ-Hefutoxin1, a Novel Toxin from the ScorpionHeterometrus fulvipes with Unique Structure and Function (2002) (10)
Pharmacological comparison of two different insect models using the scorpion alpha-like toxin BmK M1 from Buthus martensii Karsch. (2005) (9)
Detection and quantification of the hypnotic zopiclone, connected with an uncommon case of drowning. (1996) (9)
Protein surface topography as a tool to enhance the selective activity of a potassium channel blocker (2019) (9)
Screening of Urine and Blood Using Limited Sample Preparation and Information Dependent Acquisition with LC-MS/MS as Alternative for Immunoassays in Forensic Toxicology (2013) (9)
Electrophysiological characterization of Tityus obscurus β toxin 1 (To1) on Na+-channel isoforms. (2019) (9)
Redox state dependency of HERGS631C channel pharmacology: relation to C‐type inactivation (2000) (9)
Purification and biochemical characterization of VesT1s, a novel phospholipase A1 isoform isolated from the venom of the greater banded wasp Vespa tropica (2018) (9)
Small cyclic sodium channel inhibitors. (2020) (9)
Application of the characteristic function to evaluate and compare analytical variability in an external quality assessment scheme for serum ethanol. (2015) (9)
Voltage-sensor conformation shapes the intra-membrane drug binding site that determines gambierol affinity in Kv channels (2016) (9)
Unraveling the peptidome of the South African cone snails Conus pictus and Conus natalis (2013) (8)
Mutations in the P-region of a mammalian potassium channel (RCK1): a comparison with the Shaker potassium channel. (1994) (8)
Solvent-free sample preparation by headspace solid-phase microextraction applied to the tracing of n-butyl nitrite abuse (2005) (8)
Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro. (2019) (8)
Potassium Channel Blockers in Mesobuthus eupeus 1 Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1: an Integrated Transcriptomic and Proteomic Study* (2015) (8)
First report on BaltCRP, a cysteine-rich secretory protein (CRISP) from Bothrops alternatus venom: Effects on potassium channels and inflammatory processes. (2019) (8)
Is there a link between protein pICln and volume-regulated anion channels? (1998) (7)
PhcrTx2, a New Crab-Paralyzing Peptide Toxin from the Sea Anemone Phymanthus crucifer (2018) (7)
C-Terminal residues in small potassium channel blockers OdK1 and OSK3 from scorpion venom fine-tune the selectivity. (2017) (7)
Towards toxin PEGylation: The example of rCollinein-1, a snake venom thrombin-like enzyme, as a PEGylated biopharmaceutical prototype. (2021) (7)
3D Pharmacophore-Based Discovery of Novel KV10.1 Inhibitors with Antiproliferative Activity (2021) (7)
Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa. (2019) (7)
Medical Findings and Toxicological Analysis in Infant Death by Balloon Gas Asphyxia: A Case Report. (2017) (7)
A novel m -conopeptide, CnIIIC, exerts potent and preferential inhibition of Na V 1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors (2012) (6)
Voltage-gated sodium channels are targets for toxins from the venom of the spider Heriaeus melloteei (2009) (6)
AaHIV a sodium channel scorpion toxin inhibits the proliferation of DU145 prostate cancer cells. (2020) (6)
Ionic Liquid‐Based Liquid–Liquid Microextraction for Benzodiazepine Analysis in Postmortem Blood Samples (2018) (6)
Antinociceptive effects of new pyrazoles compounds mediated by the ASIC-1α channel, TRPV-1 and μMOR receptors. (2019) (6)
A neolignan-type impurity arising from the peracid oxidation reaction of anethole in the surreptitious synthesis of 4-methoxyamphetamine (PMA). (2004) (6)
Valorisation of battery recycling slags (2011) (6)
Tuning Scorpion Toxin Selectivity: Switching From KV1.1 to KV1.3 (2020) (6)
Kbot55, purified from Buthus occitanus tunetanus venom, represents the first member of a novel α-KTx subfamily (2016) (6)
Characterization of Kbot21 Reveals Novel Side Chain Interactions of Scorpion Toxins Inhibiting Voltage-Gated Potassium Channels (2015) (6)
Technical Note A Rapid and Simple GC/MS Screening Method for 4-Methoxyphenol in Illicitly Prepared 4-Methoxyamphetamine (PMA) (2003) (5)
Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning. (2016) (5)
Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain (2021) (5)
The P2Y1 Receptor Antagonist Adenosine-2’,5’-Diphosphate Non-selectively Antagonizes the Platelet P2X1 Ion Channel (2001) (5)
Transmembrane segments critical for potassium channel function. (1995) (5)
Phoneutria nigriventer Spider Toxin PnTx2-1 (δ-Ctenitoxin-Pn1a) Is a Modulator of Sodium Channel Gating (2018) (5)
Synthesis and Characterization of Spinoxin, a Novel Peptide Toxin from the Malaysian Black Scorpion (2004) (5)
Analgesic and neuropsychological effects of Echinacea N-alkylamides (2008) (5)
The Health Risks of Belgian Illicit Indoor Cannabis Plantations (2018) (5)
Two recombinant depressant scorpion neurotoxins differentially affecting mammalian sodium channels. (2010) (5)
Pioneering Study on Rhopalurus crassicauda Scorpion Venom: Isolation and Characterization of the Major Toxin and Hyaluronidase (2020) (4)
Refined structure of BeM9 reveals arginine hand, an overlooked structural motif in scorpion toxins affecting sodium channels (2018) (4)
Anise Oil as a Precursor for 2-Alkoxy-5-methoxybenzaldehydes (2004) (4)
Morphine-6β-glucuronide and morphine-3-glucuronide, opioid receptor agonists with different potencies11Abbreviations: M3G, morphine-3-glucuronide; M6G, morphine-6β-glucuronide; MOR, μ-opioid receptor; KOR, κ-opioid receptor; DOR, δ-opioid receptor; GIRK channel, G-protein coupled inwardly rectifying (2001) (4)
Jaburetox, a natural insecticide derived from Jack Bean Urease, activates voltage-gated sodium channels to modulate insect behavior. (2019) (4)
Adaptively evolved human oral actinomyces‐sourced defensins show therapeutic potential (2021) (4)
A Tale of Toxin Promiscuity: The Versatile Pharmacological Effects of Hcr 1b-2 Sea Anemone Peptide on Voltage-Gated Ion Channels (2022) (4)
Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the K(+) pore. (2016) (4)
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone (2021) (4)
Subtype Specificity of β-Toxin Tf1a from Tityus fasciolatus in Voltage Gated Sodium Channels (2018) (4)
Design and characterization of a novel structural class of Kv1.3 inhibitors. (2020) (4)
Ala-7, His-10 and Arg-12 are crucial amino acids for activity of a synthetically engineered μ-conotoxin (2014) (4)
The new COST Action European Venom Network (EUVEN)—synergy and future perspectives of modern venomics (2021) (4)
Cooperative and noncooperative subunit interactions determine voltage-dependent k+ channel gating (1993) (4)
Design of sodium channel ligands with defined selectivity – a case study in scorpion alpha‐toxins (2017) (4)
Differentiation between decomposed remains of human origin and bigger mammals. (2017) (4)
Identification and Characterization of a Peptide from the Stony Coral Heliofungia actiniformis. (2020) (3)
New insights in the mode of action of (+)-erythravine and (+)-11α-hydroxy-erythravine alkaloids. (2020) (3)
Kunitz-Type Peptides from Sea Anemones Protect Neuronal Cells against Parkinson’s Disease Inductors via Inhibition of ROS Production and ATP-Induced P2X7 Receptor Activation (2022) (3)
2.15 – Natural Peptide Toxins (2010) (3)
The venom of the Asian scorpion Buthus martensi Karsch: an overview of the toxins and their biological targets (2009) (3)
Neurotoxic and convulsant effects induced by Jack Bean Ureases on the Mammalian Nervous System. (2021) (3)
Multi-Site Binding Of A General Anesthetic To The Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC (2013) (3)
Potassium channel blocker crafted by ɑ-hairpinin scaffold engineering. (2021) (3)
Novel scorpion K+ channel toxins isolated from venoms of species belonging to the Parabuthus genus (1998) (3)
Jellyfish and other cnidarians cause pain by affecting TRPV1 channels (2006) (3)
Evaluation of the suitability of ionic liquid‐based liquid‐liquid microextractions for blood protein removal (2019) (3)
Development and optimization of a purification strategy for the venom of the scorpion Parabuthus transvaalicus. (1997) (3)
The Poison Dart frog's batrachotoxin modulates Na(nu)1.8 (2005) (3)
t‐boc synthesis of huwentoxin‐i through native chemical ligation incorporating a trifluoromethanesulfonic acid cleavage strategy (2016) (3)
A possible structural link between voltage-gated and inward rectifier k+ channels (1994) (3)
Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity (2022) (3)
New Diarylamine KV10.1 Inhibitors and Their Anticancer Potential (2022) (3)
Oleamide in Ipomoea and Dillenia species and inflammatory activity investigated through ion channel inhibition. (2020) (3)
Synthesis and biological evaluation of piperazine derivatives as novel isoform selective voltage-gated sodium (Nav) 1.3 channel modulators (2015) (3)
Toxins and potassium channels. (2004) (3)
Cyclic Peptides as T-Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site. (2021) (3)
Design of Bioactive Peptides from Naturally Occurring (2012) (3)
Profiling volatile organic compounds of decomposition (2017) (3)
Validation of a fast ionic liquid-based dispersive liquid-liquid microextraction procedure combined with LC-MS/MS analysis for the quantiﬁcation of benzodiazepines in whole blood (2017) (2)
New Insectotoxin from Tibellus Oblongus Spider Venom Presents Novel Adaptation of ICK Fold (2021) (2)
Consequences of decontamination procedures in forensic hair analysis using MetA-SIMS analysis (2016) (2)
A Pseudoscorpion's Promising Pinch: The Venom of Chelifer cancroides Contains a Rich Source of Novel Compounds. (2021) (2)
Effect of the bradycardic agent UL-FS 49 on cardiac L- and T-type Ca channels (1990) (2)
Synthesis and electrophysiological characterization of cyclic morphiceptin analogues. (2004) (2)
Role of individual disulfide bridges in the conformation and activity of spinoxin (α-KTx6.13), a potassium channel toxin from Heterometrus spinifer scorpion venom. (2016) (2)
Compound Heterozygous SCN5A Mutations in Severe Sodium Channelopathy With Brugada Syndrome: A Case Report (2020) (2)
Quantification of cocaine and benzoylecgonine in wastewater by gas chromatography-mass spectrometry: mapping cocaine abuse in the Belgian university city of Leuven (2006) (2)
LC-MS/MS in forensic toxicology: what about matrix effects? (2011) (2)
Membrane topology of rck1 k-channels (1992) (2)
Artificial Peptide Ligand of Potassium Channel KV1.1 with High Selectivity (2021) (2)
Functional Characterization of the Nemertide α Family of Peptide Toxins (2021) (2)
13. Crotamine Pharmacology Revisited: Novel Insights Based on the Inhibition of Kv Channels (2012) (2)
AsKC11, a Kunitz Peptide from Anemonia sulcata, Is a Novel Activator of G Protein-Coupled Inward-Rectifier Potassium Channels (2022) (2)
14. When cone snails and spiders meet: Design of selective and potent sodium channel inhibitors (2014) (2)
Anti-inflammatory and detoxification activities of some Ipomoea species determined by ion channel inhibition and their phytochemical constituents (2021) (2)
De Novo Transcriptome Analysis of the Venom of Latrodectus geometricus with the Discovery of an Insect-Selective Na Channel Modulator (2021) (2)
Effects of deletion and insertion of amino acids on the activity of HelaTx1, a scorpion toxin on potassium channels. (2016) (2)
Isolation and characterization of FMRFamide-like peptides in the venoms of solitary sphecid wasps (2021) (2)
Scorpion toxin MeuNaTxα‐1 sensitizes primary nociceptors by selective modulation of voltage‐gated sodium channels (2020) (2)
51. Evolution of a Neurotoxin from a Defensin (2012) (2)
The Kunitz-type HCRG peptides from the sea anemone Heteractis crispa possess Kv channel toxicity (2019) (1)
Norpropoxyphene-induced facilitation and block of HERG and KVLQT1+minK currents, associated with changes in ion-selectivity and gating (1999) (1)
In Silico and In Vitro Structure–Activity Relationship of Mastoparan and Its Analogs (2022) (1)
GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. (2020) (1)
Newly Discovered Peptides from the Coral Heliofungia actiniformis Show Structural and Functional Diversity. (2022) (1)
Analytical performance of eight enzymatic assays for ethanol in serum evaluated by data from the Belgian external quality assessment scheme (2022) (1)
HCN channels in the heart. (2022) (1)
Three-dimensional solution structure of spinoxin, a potassium channel blocker (2005) (1)
Fast protein liquid chromatography for the purification of animal venoms. (1996) (1)
Artificial pore blocker acts specifically on voltage-gated potassium channel isoform KV1.6 (2022) (1)
Recombinant Production and Structure–Function Study of the Ts1 Toxin from the Brazilian Scorpion Tityus serrulatus (2019) (1)
Synthetic polypeptide crotamine: characterization as a myotoxin and as a target of combinatorial peptides (2021) (1)
WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels (2021) (1)
441 Why anticholinergics fail: Oxybutynin and fesoterodine induce a shift from muscarinergic to purinergic transmission in the rat bladder (2013) (1)
Venom components with insecticidal activity found in major animal phyla (2019) (1)
Screening of 453 compounds in urine and blood using limited sample preparation and information dependent acquisition with LC-MS/MS: a trustworthy alternative for immunoassays in forensic toxicology? (2013) (1)
Shedding new lights on the recombinant β-KTx neurotoxin from Tityus serrulatus: heterologous expression, structural and functional characterization. (2021) (1)
A Centipede Toxin Family Defines a New Ancient Class of CSαβ Defensins (2018) (1)
13. Sea anemone toxins: from lab bench discovery to commercial drugs? (2014) (1)
P9: A closer look to the effect of external influences on cocaine in hair using imaging mass spectrometry (2014) (1)
Dimeric and tetrameric channels made from wildtype and mutant rck1-k channels (1992) (1)
Imaging mass spectrometry revealing the consequences of decontamination procedures in forensic hair analysis (2014) (1)
The use-dependent effect of verapamil on ca-channels in guinea-pig ventricular myocytes (evidence for active state block and potential-dependency) (1988) (1)
Toxin bioportides: exploring toxin biological activity and multifunctionality (2016) (1)
Pharmacological activity and NMR solution structure of the leech peptide HSTX-I. (2020) (1)
Beyond hemostasis: A potassium channel blocker snake venom serine protease with potential antitumor activity. (2020) (1)
Corrigendum to “Jellyfish and other cnidarian envenomations cause pain by affecting TRPV1 channels” [FEBS Lett. 580 (2006) 5728–5732] (2007) (1)
α-nemertides, a novel family of marine peptide neurotoxins from ribbon worms (2019) (1)
Transgenerational epigenetic effects from male exposure to endocrine-disrupting compounds: a systematic review on research in mammals (2020) (1)
110. Voltage Sensor Trapping in Voltage-Gated K-Channels by the Marine Neurotoxin Gambierol (2012) (1)
beta/delta-Agatoxins are unique modulators of voltage-gated sodium channels (2010) (1)
The voltage-gated potassium channel Kv10.1, a target for novel anticancer peptides (2016) (1)
A Natural Point Mutation Reveals Target Promiscuity of Toxins Isolated from the Sea Anemone Anthopleura Elegantissima (2012) (1)
Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica (2022) (1)
Expression of an α-KTx from Tityus serrulatus scorpion venom in Pichia pastoris yeast and its preliminary electrophysiological characterization. (2020) (1)
A Gating Modulator Peptide Toxin for Shaker-Type KV1 Channels Derived from the Sea Anemone Bunodosoma cangicum (2013) (0)
30. Structure function relationship study of Kbot21, a new potassium channel blocker from the Tunisian scorpion Buthus occitanus tunetanus (2014) (0)
Pharmacological Screening of Venoms from Five Brazilian Micrurus Species on Different Ion Channels (2022) (0)
48. Isolation and characterization of novel conopeptides from Conus amadis that target voltage-gated sodium channels (2014) (0)
TRPV1 channels as key determinant in marine intoxication (2007) (0)
Resource savings by 'Advanced Battery Recycling' (2011) (0)
Evolutionary Diversification of Mesobuthus (cid:1) -Scorpion Toxins Affecting Sodium Channels* □ S (2011) (0)
Mode of action of antifungal plant defensins and their synergy with conventional antimycotics (2016) (0)
Alternative post-mortem forensic toxicology specimens: detecting psychotropics in bone (2012) (0)
High sensitive UFLC-MS/MS analysis of fentanyl and norfentanyl in different post-mortem matrices: seven forensic cases (2010) (0)
Potent Kv1.3 block by gambierol (2008) (0)
KV1.2-Selective Peptide with High Affinity (2022) (0)
Two novel scorpion toxins specifically modulating Nav1.4 and Nav1.7 (2010) (0)
Transcriptome analysis of the scorpion Hadrurus spadix (Scorpiones, Iuridae): information of the cDNA library from the venom gland (2008) (0)
Structure-function relationships of spinoxin, a peptide neurotoxin from scorpion venom (2015) (0)
Peptide ion channel toxins from the bootlace worm, the longest animal on Earth (2018) (0)
Synthesis and Characterization of k-Hefutoxin-1 Analogs (2004) (0)
NMR SOLUTION STRUCTURE OF ALPHA CONOTOXIN LO1A FROM Conus longurionis (2014) (0)
Structural Optimization of an α-Hairpinin Blocking Potassium Channels KV1.3 (2023) (0)
Synthesis and biological evaluation of piperazine derivatives as novel isoform selective voltage-gated sodium (Nav) 1.3 channel modulators (2014) (0)
Are bloodspots usable in postmortem forensic toxicology (2013) (0)
Illegale drugs: Focus op phenylethylamines (2004) (0)
The mechanism of action of microalgal toxins interacting with NaV and KV channels (2014) (0)
Transmembrane segments critically involved in potassium channel function (1995) (0)
Pegylating toxins: A new trend in toxinology? A successful example of a PEGylated snake venom serine protease. (2020) (0)
kappa-Hefutoxins: a novel Class of Potassium Channel Toxins from Scorpion venom (2002) (0)
Ala-7, His-10 and Arg-12 are crucial amino acids for activity and potency of an engineered µ-Conotoxin (2013) (0)
Pharmacological Properties of Cinnamaldehyde on NaChBac (2014) (0)
Solution Structure and Alanine Scan of a Spider Toxin That Affects the Activation of Mammalian Voltage-gated (2007) (0)
MMTS-modified Y53C mutant of Aplysia AChBP in complex with acetylcholine (2010) (0)
Functional characterization of the nemertide alpha family of peptide toxins (2019) (0)
Crystal Structure Of Mutant K8DP9SR58KP60G Of Scorpion alpha-Like Neurotoxin Bmk M1 From Buthus Martensii Karsch (2006) (0)
Voltage-Gated Sodium Channels Are Targets for Toxins from the Venom of the Spider Heriaeus melloteei 1 (0)
In-depth characterization of HelaTx1, A scorpion toxin targeting Kv channels (2019) (0)
Artificial Peptide Ligand of Potassium Channel KV1.1 with High Selectivity (2021) (0)
Validation of a TD-GC/MS method on the search for human specific decomposition products (2014) (0)
Ionic liquids as promising solvents for the fast and easy extraction of benzodiazepines in whole blood samples (2016) (0)
Synthesis and Characterization of κ-Hefutoxin 1 Analogs with Amino Acid Deletion (2013) (0)
Flunarizine blocks inward and outward current through cardiac calcium channels (1988) (0)
Evidence for TRPV1 activity as a pain causing mechanism in jellyfish and other Cnidaria envenomations (2006) (0)
Crotamine Toxicity Revisited: Novel Insights Based on KV Channel Inhibition (2012) (0)
Apamin structure and pharmacology revisited (2022) (0)
Synthetic polypeptide crotamine: characterization as a myotoxin and as a target of combinatorial peptides (2021) (0)
The Mediterranean scorpion Mesobuthus gibbosus (Scorpiones, Buthidae): transcriptome analysis and organization of the genome encoding chlorotoxin-like peptides (2014) (0)
Different use-dependent modulation of GIRK1/GIRK2 channel gating in the absence and presence of RGS4 (2001) (0)
Both pI(Cln) and ClC-6 activate I-Cln an endogenous chloride current in Xenopus oocytes, which differs from I(Cl,swell) (1997) (0)
PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold (2018) (0)
The insecticidal wasp toxin Γ-Pompilidotoxin is a linear peptide modulating voltage-gated sodium channels. (2020) (0)
(ELIC) Ligand-gated Ion Channel chrysanthemi Erwinia to the Prokaryotic Pentameric Multisite Binding of a General Anesthetic (2014) (0)
Comparative analysis of post-mortem remains from human and animal origin: perspectives of a future study (2007) (0)
Solution structure of insectidal toxin delta-paluIT2-NH2 (2005) (0)
NMR SOLUTION STRUCTURE OF SCORPION VENOM TOXIN Ts11 (TsPep1) FROM Tityus serrulatus (2015) (0)
BcsTx 3 is a founder of a novel sea anemone toxin family of potassium channel blocker Running title : BcsTx 3 , a novel sea anemone type of KV-blocker (2013) (0)
Author Index (2006) (0)
Delta-8-Tetrahydrocannabinol, an emerging NPS and other structurally related cannabinoids (2022) (0)
Exploring the Effect of Gambierol on the Gating Machinery of Kv3.1 Channels (2014) (0)
Biochemistry and physiology of spider venom (2007) (0)
NMR solution structure of Midi peptide designed based on m-conotoxins (2012) (0)
Reversal ofrectification andalteration ofselectivity and pharmacology inamammalianKv1.1potassium channel by deletion ofdomains SItoS4 (2011) (0)
Characterization of the scorpion toxin κ-hefutoxin 1 as the first peptide inhibitor of the potassium channel Kv10.1 (2014) (0)
Isolation and characterization of components with proteolytic activity present in fraction II-III from Tityus serrulatus venom. (2020) (0)
Discovery of buried cadavvers using detection and analysis of volatile decomposition compounds (2012) (0)
Synthesis and Structure-Activity Relationships of Peptide Toxins Isolated from Asian Scorpion Heterometrus Fulvipes and Heterometrus Spinifer (2006) (0)
Peptide toxins from the longest animal on earth (2016) (0)
E5 - Recycling of EV batteries: Legal context and Umicore technology (2013) (0)
Concurrent appearance of vanoxerine, mCPP and 'wormazine' on the Belgian market: a case study (2007) (0)
Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities (2020) (0)
34. Miniaturization of μ-Conotoxins as Peptidomimetic Strategy to Develop Selective Sodium Channel Blockers (2012) (0)
Electrophysiological characterization of Ts15, a new toxin from Tityus serrulatus venom (2010) (0)
Four novel tarantula toxins acting as potent and selective ligands on TTX-r and TTX-s voltage-gated Na+ channels (2005) (0)
Solution structure by NMR means of delta-paluIT1-NH2 (2005) (0)
Scorpion transcriptome secrets: molecular biodiversity from Pandinus cavimanus and Hadrurus spadix (2011) (0)
Quinazolinone dimers as a potential new class of safer Kv1 inhibitors: Overcoming hERG, sodium and calcium channel affinities. (2021) (0)
A possible link between Prozac(R), the 5-HT3 syndrome and Kv1.1 channels (1997) (0)
Characterization and structure elucidation of an α-conotoxin Lo1a from Conus longurionis (2014) (0)
Selectivity of voltage-activated k+ and na+ channels probed by multimeric cdnas and 3-d modeling (1994) (0)
Steve Peigneur, Diego J. B. Orts, Alvaro R. Prieto da Silva, Nancy Oguiura, (2012) (0)
Purification and characterization of a new toxin from Tityus serrulatus venom (2012) (0)
The use of ionic liquids for the fast and simple extraction of benzodiazepines from complex biological samples (2015) (0)
Modulation of gating and kinetics of HCN1 and HCN2 by activation of the mu-opioid receptor (2000) (0)
Cover Image, Volume 86, Issue 10 (2018) (0)
Detection of 453 compounds in urine and whole blood using LC-MS/MS screening with limited sample preparation: a trusthworthy alternative for immunoassays? (2013) (0)
Newly Cloned Threshold Channels (2011) (0)
Isolation and characterization of Phlotoxin 1, a novel peptide from spider venom acting selectively on voltage-gated Na+ channels (2005) (0)
The advantage of a high pH mobile phase in UPLC-MS/MS analysis of benzodiazepine(-like) hypnotics in urine and blood (2012) (0)
The interaction between Gigantoxin I and TRPV1 is PLA2 pathway dependent (2008) (0)
Corrigendum to “Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK” [Peptides 99 (2018) 169–178] (2018) (0)
Serine 329 of the (cid:1) -Opioid Receptor Interacts Differently with Agonists (2003) (0)
OD1 and PhlYx, two novel, potent modulators of Nav1.7: potential use as analgesic through different mechanisms (2006) (0)
The P2X1 ion channel in platelets acts as a functional receptor for ATP and is weakly antagonized by ADP. (2001) (0)
Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the pore Reference: (2016) (0)
Hydrogen peroxide effect on cocaine in users hair using imaging mass spectrometry (2014) (0)
Solution structure and functional analysis of HelaTx1: the first toxin member of the κ-KTx5 subfamily (2020) (0)
Recombinant Production and Structure–Function Study of the Ts1 Toxin from the Brazilian Scorpion Tityus serrulatus (2019) (0)
Derivative of Scorpion Neurotoxin BeM9 Is Selective for Insect Voltage-Gated Sodium Channels (2021) (0)
Title: New insights in the mode of action of (+)-erythravine and (+)-11 α -hydroxy- 1 erythravine alkaloids (2020) (0)
Synthesis and Characterization of Spinoxin Analogs with Disulfide Bond Deletion (2013) (0)
Pumiliotoxin 251D: a modulator of voltage-gated ion channels (2005) (0)
Identification of potential anticancer toxins: A focus on KV10.1 inhibitors (2019) (0)
D and mutagenesis-induced changes in the selectivity filter of a (2003) (0)
Corrigendum to: The new COST Action European Venom Network (EUVEN)—synergy and future perspectives of modern venomics (2021) (0)
A search for efficacious, potent and selective ligands acting on cloned voltage-gated Na+ channels (2003) (0)
Heterologous expression of Ts8, a neurotoxin from Tityus serrulatus venom, evidences its antifungal activity. (2022) (0)
268. Biological activities of PnTx2-6, an exciting toxin from spider Phoneutria nigriventer (2012) (0)
Conus australis, an as yet unexplored Conus sp. with novel conotoxins (2015) (0)
Trends in Pharmaceutical Research and Development Vol. 6 (2020) (0)
Isolation and Characterization of the First Known Inhibitor Cystine Knot Peptide in Sea Anemone: Inhibitory Activity on Acid-Sensing Ion Channels (2017) (0)
MTSET-modified Y53C mutant of Aplysia AChBP (2010) (0)
New Sea Anemone Toxin RTX-VI Selectively Modulates Voltage-Gated Sodium Channels (2020) (0)
Redox state, inactivation gating and ion selectivity of the S631CHERG mutant: Effect of pharmacology (2000) (0)
Transient receptor potential vanilloid 1 and xenobiotics. (2008) (0)
New Kv, NAv, and ASIC channel toxins from the sea anemone Heteractis crispa (2019) (0)
Solution structure of the N(1-21)MeuTXK-beta in presence of TFE (2010) (0)
Solution structure and alanine scan of a spider toxin that affects the activation of mammalian sodium channels (2006) (0)
Identification of decomposition products from human and animal remains using TD-GC/MS (2013) (0)
Ionic liquids as promising extraction solvents in forensic toxicology (2018) (0)
Unveiling the activities of PNPP-19, a toxin-derived synthetic peptide (2020) (0)
Alternative splicing generates truncated CLC-6 isoforms that activate exogenous chloride channels when expressed in Xenopus oocytes (1997) (0)
Unraveling the venom chemistry with evidence for histamine as key regulator in the envenomation by caterpillar Automeris zaruma (2022) (0)
Drug discovery and bio-exploration of nature: toxins, friend or foe? (2022) (0)
Antinociceptive effect induced by a PnPP-19 derivative: new insights into venom peptides targeting opioid receptors (2019) (0)
Drug- and mutagenesis-induced changes in the selectivity filter of a 2-pore background K+ channel (2003) (0)
Information dependent acquisition with LC-MS/MS as a tool for screening of 453 compounds in forensic urine and whole blood samples (2013) (0)
Pain induction by Cnidaria venom: the crucial role of TRPV1 as a target for indirect activation by gigantoxin I from the sea anemone Stichodactyla gigantea (2008) (0)
Parabutoporin, a novel antibacterial peptide from scorpion venom, induces G-protein dependent Ca2+ release in eukaryotic cells (2002) (0)
The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors (2018) (0)
AgTx2-GFP, Fluorescent Blocker Targeting Pharmacologically Important Kv1.x (x = 1, 3, 6) Channels (2023) (0)
SOLUTION STRUCTURE OF THE SOMATOSTATIN SST3 RECEPTOR ANTAGONIST TAU- CONOTOXIN CnVA (2013) (0)
Structure of the SthK Carboxy-Terminal Region in complex with cAMP (2015) (0)
Do inward and outward rectifier K+ channels (1996) (0)
Purification and Characterization of Bot33: A Non-Toxic Peptide from the Venom of Buthus occitanus tunetanus Scorpion (2022) (0)
Converting a plant defense peptide into a potassium channel blocker (2013) (0)
Effect of a pore-forming peptide isolated from the venom of Parabuthus scorpions on granulocytes (2000) (0)
The use of ionic liquids for the fast extraction of benzodiazepines in complex biological samples (2015) (0)
Development and validation of a highly sensitive UFLC-MS/MS method for the analysis of fentanyl and its major metabolite norfentanyl in urine and whole blood in forensic context (2010) (0)
Purification and characterization of conotoxins from C. asiaticus, C. australis and C. longurionis (2014) (0)
Heterologous expression of a neurotoxin from Tityus serrulatus scorpion venom in Pichia pastoris yeast and the evaluation of its glycosylation patterns (2021) (0)
S117 CHARACTERIZATION OF THE EFFECT OF BDS 391, AN ANALGESIC COMPOUND, ON 5-HT3 RECEPTORS AND ION CHANNELS (2011) (0)
Screening of animal venoms in the search for new and selective neurotoxins with potassium channel inhibitory activity (1997) (0)
Modulation of HCN1 and HCN2 pacemaker channels by G protein-coupled receptors (2001) (0)
Research into the Bioengineering of a Novel α-Conotoxin from the Milked Venom of Conus obscurus (2022) (0)
UFLC-MS/MS as screening and/or quantification tool for analysis of 28 benzodiazepines and non-benzodiazepine related hypnotics in urine and whole blood (2009) (0)
Solution structure of the skeletal muscle and neuronal voltage gated sodium channel antagonist mu-conotoxin CnIIIC (2012) (0)
Molecular basis of the mammalian and insecticidal potency of the scorpion alpha-like toxin, BmK M1 (2005) (0)
Synthesis and Characterization of Disulfide Bond Isomers of κ-Hefutoxin-1 (2003) (0)
Biochemical, Functional and Structural Characterization of a Family of Prokaryote Voltage-Gated Calcium Channels (2013) (0)
Does pI(Cln) represent a plasma-membrane located anion channel? (1997) (0)
Hazards of illicit cannabis cultivation for the general public, users and intervention staff (2016) (0)
Structure-Function Studies of Sponge-Derived Compounds on the Cardiac CaV3.1 Channel (2023) (0)

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