Janardan K. Reddy

Janardan K. Reddy's AcademicInfluence.com Rankings

Janardan K. Reddy

Medical

#1041

World Rank

#1336

Historical Rank

Pharmacology

#75

World Rank

#98

Historical Rank

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Medical

Janardan K. Reddy's Degrees

PhD Pharmacology University of California, San Francisco
Doctorate Medicine University of California, San Francisco

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Janardan K. Reddy's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors (2006) (946)
Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. (1996) (906)
Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens (1980) (835)
PEROXISOMAL β-OXIDATION AND PEROXISOME PROLIFERATOR–ACTIVATED RECEPTOR α: An Adaptive Metabolic System (2001) (804)
Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation. (2006) (781)
Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoforms. (1995) (673)
Adipocyte-specific Gene Expression and Adipogenic Steatosis in the Mouse Liver Due to Peroxisome Proliferator-activated Receptor γ1 (PPARγ1) Overexpression* (2003) (531)
Application of comparative functional genomics to identify best-fit mouse models to study human cancer (2004) (458)
Defect in Peroxisome Proliferator-activated Receptor α-inducible Fatty Acid Oxidation Determines the Severity of Hepatic Steatosis in Response to Fasting* (2000) (435)
Peroxisomal lipid metabolism. (1994) (425)
Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. (1993) (376)
Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system. (2001) (372)
Steatohepatitis, Spontaneous Peroxisome Proliferation and Liver Tumors in Mice Lacking Peroxisomal Fatty Acyl-CoA Oxidase (1998) (346)
Isolation and Characterization of PBP, a Protein That Interacts with Peroxisome Proliferator-activated Receptor* (1997) (345)
Hepatic peroxisome proliferation: induction by two novel compounds structurally unrelated to clofibrate (1975) (336)
Carcinogenesis by hepatic peroxisome proliferators: evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. (1983) (324)
Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression. (2006) (320)
Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators. (1986) (312)
Peroxisome proliferation and hepatocarcinogenesis. (1987) (304)
Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. (2003) (293)
Activation of flavin-containing oxidases underlies light-induced production of H2O2 in mammalian cells. (1999) (285)
PPARα: energy combustion, hypolipidemia, inflammation and cancer (2010) (248)
Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator. (1989) (247)
Hepatocellular and Hepatic Peroxisomal Alterations in Mice with a Disrupted Peroxisomal Fatty Acyl-coenzyme A Oxidase Gene* (1996) (243)
Identification of toxicologically predictive gene sets using cDNA microarrays. (2001) (238)
Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. (1992) (238)
Transcription coactivators for peroxisome proliferator-activated receptors. (2007) (237)
HEPATIC AND RENAL EFFECTS OF PEROXISOME PROLIFERATORS: BIOLOGICAL IMPLICATIONS * (1982) (227)
Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis. (2000) (224)
Hepatic peroxisome (microbody) proliferation in rats fed plasticizers and related compounds. (1978) (218)
Peroxisomal and Mitochondrial Fatty Acid β-Oxidation in Mice Nullizygous for Both Peroxisome Proliferator-activated Receptor α and Peroxisomal Fatty Acyl-CoA Oxidase (1999) (204)
Identification of a Peroxisome Proliferator-responsive Element Upstream of the Human Peroxisomal Fatty Acyl Coenzyme A Oxidase Gene (*) (1996) (204)
Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator, [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14, 643), in rat and mouse liver. (1979) (200)
Oxidative DNA damage caused by persistent peroxisome proliferation: its role in hepatocarcinogenesis. (1989) (197)
III. Peroxisomal β-oxidation, PPARα, and steatohepatitis (2001) (196)
Isolation and Characterization of Peroxisome Proliferator-activated Receptor (PPAR) Interacting Protein (PRIP) as a Coactivator for PPAR* (2000) (195)
Excessive accumulation of autofluorescent lipofuscin in the liver during hepatocarcinogenesis by methyl clofenapate and other hypolipidemic peroxisome proliferators. (1982) (192)
Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma. (1996) (192)
Coactivators in PPAR-Regulated Gene Expression (2010) (185)
Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer. (1999) (184)
Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor alpha to Wy-14,643-induced liver tumorigenesis. (2006) (179)
Peroxisome proliferator-activated receptors, coactivators, and downstream targets (2007) (177)
Peroxisome proliferator-activated receptors, fatty acid oxidation, steatohepatitis and hepatocarcinogenesis. (2003) (172)
Peroxisomal β-Oxidation and Steatohepatitis (2001) (167)
Hepatocellular carcinomas in acatalasemic mice treated with nafenopin, a hypolipidemic peroxisome proliferator. (1976) (165)
Properties of hypolipidemic peroxisome proliferators in the lymphocyte [3H]thymidine and Salmonella mutagenesis assays. (1980) (164)
Comparison of constitutive and inducible levels of expression of peroxisomal beta-oxidation and catalase genes in liver and extrahepatic tissues of rat. (1988) (157)
Tumorigenicity of the hypolipidaemic peroxisome proliferator ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) in rats. (1979) (148)
Malignant tumors in rats fed nafenopin, a hepatic peroxisome proliferator. (1977) (148)
Induction of hepatic peroxisome proliferation in nonrodent species, including primates. (1984) (145)
HYPOLIPIDEMIC HEPATIC PEROXISOME PROLIFERATORS FORM A NOVEL CLASS OF CHEMICAL CARCINOGENS (1980) (144)
Peroxisome proliferation and lipid peroxidation in rat liver. (1986) (143)
Deletion of PBP/PPARBP, the Gene for Nuclear Receptor Coactivator Peroxisome Proliferator-activated Receptor-binding Protein, Results in Embryonic Lethality* (2000) (139)
Identification of a transcriptionally active peroxisome proliferator-activated receptor α-interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator (2002) (134)
Evaluation of Selected Hypolipidemic Agents for the Induction of Peroxisomal Enzymes and Peroxisome Proliferation in the Rat Liver (1983) (133)
Defects of the Heart, Eye, and Megakaryocytes in Peroxisome Proliferator Activator Receptor-binding Protein (PBP) Null Embryos Implicate GATA Family of Transcription Factors* (2002) (126)
Di-(2-ethylhexyl)phthalate: An industrial plasticizer induces hypolipidemia and enhances hepatic catalase and carnitine acetyltransferase activities in rats and mice (1976) (125)
Induction and origin of hepatocytes in rat pancreas (1984) (123)
Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal beta-oxidation, PPAR alpha, and steatohepatitis. (2001) (122)
Morphometric analysis of the ultrastructural changes in rat liver induced by the peroxisome proliferator SaH 42-348 (1976) (122)
The hepatic effects of hypolipidemic drugs (clofibrate, nafenopin, tibric acid, and Wy-14,643) on hepatic peroxisomes and peroxisome-associated enzymes. (1978) (121)
Expression of p53 protein in precursor lesions and adenocarcinoma of human pancreas. (1994) (121)
Inhibitory effect of antioxidants ethoxyquin and 2(3)-tert-butyl-4-hydroxyanisole on hepatic tumorigenesis in rats fed ciprofibrate, a peroxisome proliferator. (1984) (120)
Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids (2012) (118)
Peroxisome proliferation and nongenotoxic carcinogenesis: Commentary on a symposium (1991) (117)
Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis. (2001) (116)
Detection of a nafenopin-binding protein in rat liver cytosol associated with the induction of peroxisome proliferation by hypolipidemic compounds. (1983) (115)
Transcription Coactivator PBP, the Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein, Is Required for PPARα-regulated Gene Expression in Liver* (2004) (115)
DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes. (1984) (114)
Ductal metaplasia of human exocrine pancreas and its association with carcinoma. (1985) (113)
Induction of hepatocytes in the pancreas of copper-depleted rats following copper repletion. (1986) (111)
Almost total conversion of pancreas to liver in the adult rat: a reliable model to study transdifferentiation. (1988) (110)
Molecular evolution of the urate oxidase-encoding gene in hominoid primates: nonsense mutations. (1991) (110)
Development of hepatocellular carcinomas and increased peroxisomal fatty acid beta-oxidation in rats fed [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (Wy-14,643) in the semipurified diet. (1981) (109)
Peroxisome Proliferator–induced Pleiotropic Responses: Pursuit of a Phenomenon a (1996) (109)
An overview of peroxisome proliferator-induced hepatocarcinogenesis. (1991) (107)
Analysis of peroxisome proliferator-induced preneoplastic and neoplastic lesions of rat liver for placental form of glutathione S-transferase and gamma-glutamyltranspeptidase. (1986) (106)
Phthalate esters as peroxisome proliferator carcinogens. (1982) (106)
Peroxisome proliterators and cancer: mechanisms and implications (1986) (104)
Differential expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) and its coactivators steroid receptor coactivator-1 and PPAR-binding protein PBP in the brown fat, urinary bladder, colon, and breast of the mouse. (1998) (102)
Absence of Spontaneous Peroxisome Proliferation in Enoyl-CoA Hydratase/l-3-Hydroxyacyl-CoA Dehydrogenase-deficient Mouse Liver (1999) (102)
Tissue specificity and species differences in the distribution of urate oxidase in peroxisomes. (1988) (101)
Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance. (2006) (100)
Hepatocarcinogenicity of dehydroepiandrosterone in the rat. (1992) (98)
Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP function (2001) (95)
MICROBODIES IN EXPERIMENTALLY ALTERED CELLS II. The Relationship of Microbody Proliferation to Endocrine Glands (1969) (94)
Malignant tumors in rats given lasiocarpine. (1972) (94)
Properties of purified carnitine acyltransferases of mouse liver peroxisomes. (1984) (93)
Differential induction and regulation of peroxisomal enzymes: predictive value of peroxisome proliferation in identifying certain nonmutagenic carcinogens. (1989) (93)
Thyroid hormone (T3) inhibits ciprofibrate-induced transcription of genes encoding beta-oxidation enzymes: cross talk between peroxisome proliferator and T3 signaling pathways. (1995) (93)
Comparison of hepatic peroxisome proliferative effect and its implication for hepatocarcinogenicity of phthalate esters, di(2-ethylhexyl) phthalate, and di(2-ethylhexyl) adipate with a hypolipidemic drug. (1986) (93)
Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice (2012) (92)
32P-postlabeling analysis of peroxisome proliferator-DNA adduct formation in rat liver in vivo and hepatocytes in vitro. (1985) (89)
The absence of gamma-glutamyl transpeptidase activity in putative preneoplastic lesions and in hepatocellular carcinomas induced in rats by the hypolipidemic peroxisome proliferator Wy-14,643. (1982) (87)
Expression of Base Excision DNA Repair Genes Is a Sensitive Biomarker for in Vivo Detection of Chemical-induced Chronic Oxidative Stress (2004) (87)
Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome. (2014) (86)
Peroxisome proliferator-binding protein: identification and partial characterization of nafenopin-, clofibric acid-, and ciprofibrate-binding proteins from rat liver. (1987) (86)
Peroxisome proliferation and nongenotoxic carcinogenesis: commentary on a symposium. (1991) (85)
Peroxisome proliferators and peroxisome proliferator-activated receptor alpha: biotic and xenobiotic sensing. (2004) (85)
Peroxisomes (microbodies) in cell pathology. (1984) (83)
Isolation of the human peroxisomal acyl-CoA oxidase gene: organization, promoter analysis, and chromosomal localization. (1994) (82)
Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells. (2001) (81)
Peroxisomal beta-oxidation and steatohepatitis. (2001) (79)
Less Extrahepatic Induction of Fatty Acid β-Oxidation Enzymes by PPARα (2000) (78)
Pancreatic adenocarcinoma in inbred guinea pigs induced by n-methyl-N-nitrosourea. (1975) (78)
Microbodies (peroxisomes) in the interstitial cells of rodent testes. (1972) (78)
Mouse steroid receptor coactivator-1 is not essential for peroxisome proliferator-activated receptor alpha-regulated gene expression. (1999) (77)
Phosphorylation of Transcriptional Coactivator Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein (PBP) (2002) (77)
Coactivator PRIP, the Peroxisome Proliferator-activated Receptor-interacting Protein, Is a Modulator of Placental, Cardiac, Hepatic, and Embryonic Development* (2003) (76)
Transcriptional Regulation of Cidea, Mitochondrial Cell Death-inducing DNA Fragmentation Factor α-Like Effector A, in Mouse Liver by Peroxisome Proliferator-activated Receptor α and γ* (2007) (76)
PPARalpha in the pathogenesis of fatty liver disease. (2004) (76)
EDGE: A Centralized Resource for the Comparison, Analysis, and Distribution of Toxicogenomic Information (2005) (74)
POSSIBLE PROPERTIES OF MICROBODIES (PEROXISOMES) MICROBODY PROLIFERATION AND HYPOLIPIDEMIC DRUGS (1973) (74)
Interaction of PIMT with Transcriptional Coactivators CBP, p300, and PBP Differential Role in Transcriptional Regulation* (2002) (73)
Induction, immunochemical identity and immunofluorescence localization of an 80 000-molecular-weight peroxisome-proliferation-associated polypeptide (polypeptide PPA-80) and peroxisomal enoyl-CoA hydratase of mouse liver and renal cortex. (1981) (73)
Immunocytochemical localization of catalase and heat-labile enoyl-CoA hydratase in the livers of normal and peroxisome proliferator-treated rats. (1982) (72)
Enhancement by Wy-14,643, a hepatic peroxisome proliferator, of diethylnitrosamine-initiated hepatic tumorigenesis in the rat. (1978) (72)
Effect of hypolipidemic peroxisome proliferators on unscheduled DNA synthesis in cultured hepatocytes and on mutagenesis in Salmonella. (1984) (72)
PPARα in the pathogenesis of fatty liver disease (2004) (71)
Transformation of mammalian cells by overexpressing H2O2-generating peroxisomal fatty acyl-CoA oxidase. (1995) (71)
Evaluation of liver cell proliferation during ciprofibrate-induced hepatocarcinogenesis. (1989) (68)
Transplantable pancreatic carcinoma of the rat (1977) (67)
Identification of cytosolic peroxisome proliferator binding protein as a member of the heat shock protein HSP70 family. (1990) (65)
Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen. (2003) (64)
PAT5A: A Partial Agonist of Peroxisome Proliferator-Activated Receptor γ Is a Potent Antidiabetic Thiazolidinedione Yet Weakly Adipogenic (2003) (64)
Cadmium-induced Leydig cell tumors of rat testis: morphologic and cytochemical study. (1973) (64)
Characterization of pancreatic-type tissue in the liver of rat induced by polychlorinated biphenyls. (1986) (63)
Sequential histologic study of rat liver during peroxisome proliferator [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]-acetic acid (Wy-14,643)-induced carcinogenesis. (1984) (63)
Progressive endoplasmic reticulum stress contributes to hepatocarcinogenesis in fatty acyl-CoA oxidase 1-deficient mice. (2011) (62)
Transcriptional Coactivator PRIP, the Peroxisome Proliferator-activated Receptor γ (PPARγ)-interacting Protein, Is Required for PPARγ-mediated Adipogenesis* (2003) (61)
The peroxisome proliferation-associated polypeptide in rat liver. (1977) (61)
Lack of Expression of Glutathione-S-transferase P, γ-Glutamyl Transpeptidase, and α-Fetoprotein Messenger RNAs in Liver Tumors Induced by Peroxisome Proliferators (1988) (61)
Hepatocarcinogenesis of Peroxisome Proliferators a (1996) (61)
Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity. (2005) (61)
Hepatic transdifferentiation in the pancreas. (1995) (60)
Human Peroxisome Proliferator-activated Receptor α (PPARα) Supports the Induction of Peroxisome Proliferation in PPARα-deficient Mouse Liver* (2001) (60)
Initiation of the division cycle of rat hepatocytes following a single injection of thioacetamide. (1969) (60)
Osteoclastoma‐like giant cell tumor of the liver (1980) (58)
MICROBODIES (PEROXISOMES) IDENTIFICATION IN INTERSTITIAL CELLS OF THE TESTIS (1972) (57)
Further evidence to suggest that microbodies do not exist as individual entities. (1973) (57)
Biochemical characterization of two functional human liver acyl-CoA oxidase isoforms 1a and 1b encoded by a single gene. (2007) (56)
Microbody proliferation in liver induced by nafenopin, a new hypolipidemic drug: comparison with CPIB. (1973) (56)
Peroxisome proliferator-activated receptor-α activation and excess energy burning in hepatocarcinogenesis. (2014) (56)
Microbodies in experimentally altered cells. 8. Continuities between microbodies and their possible biologic significance. (1971) (53)
Transcriptional regulation of Cidea, mitochondrial cell death-inducing DNA fragmentation factor alpha-like effector A, in mouse liver by peroxisome proliferator-activated receptor alpha and gamma. (2007) (53)
Response of chemically induced hepatocytelike cells in hamster pancreas to methyl clofenapate, a peroxisome proliferator (1982) (52)
Transdifferentiation of ductular cells into hepatocytes in regenerating hamster pancreas. (1990) (52)
PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid Oxidation. (2015) (52)
Cooperative Formation of Higher Order Peroxisome Proliferator-activated Receptor and Retinoid X Receptor Complexes on the Peroxisome Proliferator Responsive Element of the Rat Hydratase-Dehydrogenase Gene (*) (1995) (51)
Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice[S] (2010) (51)
Protein Profiling of Mouse Livers with Peroxisome Proliferator-Activated Receptor α Activation (2004) (51)
Human urate oxidase gene: cloning and partial sequence analysis reveal a stop codon within the fifth exon. (1990) (51)
Association of peroxisome proliferator-activated receptor and Hsp72. (1994) (51)
Transcription coactivator mediator subunit MED1 Is required for the development of fatty liver in the mouse (2011) (51)
Stimulation of liver catalase synthesis in rats by ethyl-α-p-chlorophenoxyisobutyrate (1971) (51)
Mitogenic effect in mouse liver induced by a hypolipidemic drug, nafenopin (1977) (49)
Induction of rat liver DNA alterations by chronic administration of peroxisome proliferators as detected by 32P-postlabeling. (1991) (49)
Hepatic oxidative stress activates the Gadd45b gene by way of degradation of the transcriptional repressor STAT3 (2014) (49)
Less extrahepatic induction of fatty acid beta-oxidation enzymes by PPAR alpha. (2000) (49)
Overexpression of Peroxisome Proliferator-activated Receptor-α (PPARα)-regulated Genes in Liver in the Absence of Peroxisome Proliferation in Mice Deficient in both l- and d-Forms of Enoyl-CoA Hydratase/Dehydrogenase Enzymes of Peroxisomal β-Oxidation System* (2003) (49)
Upregulation of calpastatin in regenerating and developing rat liver: Role in resistance against hepatotoxicity (2006) (48)
Critical Role for Transcription Coactivator Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein/TRAP220 in Liver Regeneration and PPARα Ligand-induced Liver Tumor Development* (2007) (48)
Conditional ablation of mediator subunit MED1 (MED1/PPARBP) gene in mouse liver attenuates glucocorticoid receptor agonist dexamethasone-induced hepatic steatosis. (2009) (47)
Irreversible inhibition of hepatic glutathione S-transferase by ciprofibrate, a peroxisome proliferator. (1984) (47)
MICROBODIES IN LEYDIG CELL TUMORS OF RAT TESTIS (1972) (47)
Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα (2010) (46)
Increase in hepatic carnitine acetyltransferase activity associated with peroxisomal (microbody) proliferation induced by the hypolipidemic drugs clofibrate, nafenopin, and methyl clofenapate. (1974) (45)
Malignant neoplasms in rats fed lasiocarpine. (1978) (45)
Stem cell potential of ductular and periductular cells in the adult rat pancreas. (1990) (45)
Neoplastic conversion of human urothelial cells in vitro by overexpression of H2O2-generating peroxisomal fatty acyl CoA oxidase. (1999) (44)
The relationship of nucleolar segregation to ribonucleic acid synthesis following the administration of selected hepatocarcinogens. (1968) (44)
Stimulation of catalase synthesis and increase of carnitine acetyltransferase activity in the liver of intact female rats fed clofibrate. (1979) (43)
The Neuronal Migration Defect in Mice with Zellweger Syndrome (Pex5 Knockout) is not Caused by the Inactivity of Peroxisomal β‐Oxidation (2002) (43)
Beta-oxidation in hepatocyte cultures from mice with peroxisomal gene knockouts. (2007) (42)
Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected]. (2010) (42)
Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1 (2010) (42)
Absence of gamma-glutamyl transpeptidase activity in neoplastic lesions induced in the liver of male F-344 rats by di-(2-ethylhexyl)phthalate, a peroxisome proliferator. (1987) (42)
PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex. (2006) (42)
Studies of pancreatic carcinogenesis in different animal models. (1984) (42)
Baculovirus expression of the Ah receptor and Ah receptor nuclear translocater. Evidence for additional dioxin responsive element-binding species and factors required for signaling. (1994) (41)
The Med1 Subunit of Transcriptional Mediator Plays a Central Role in Regulating CCAAT/Enhancer-binding Protein-β-driven Transcription in Response to Interferon-γ* (2008) (41)
Transformation of epithelial cells stably transfected with H2O2-generating peroxisomal urate oxidase. (1996) (41)
Invasive tumors induced in rats with actinomycin D. (1970) (41)
Hepatic microbody proliferation and catalase synthesis induced by methyl clofenapate, a hypolipidemic analog of CPIB. (1974) (41)
MICROBODIES IN EXPERIMENTALLY ALTERED CELLS (1969) (40)
The peroxisomal enzyme L-PBE is required to prevent the dietary toxicity of medium-chain fatty acids. (2013) (40)
Hepatic regeneration in peroxisome proliferator-activated receptor alpha-null mice after partial hepatectomy. (2002) (40)
Induction of fatty acid beta-oxidation and peroxisome proliferation in the liver of rhesus monkeys by DL-040, a new hypolipidemic agent. (1985) (39)
Dehydroepiandrosterone-induced peroxisome proliferation in the rat liver. (1992) (39)
Nuclear Receptor Coactivator 6 Mediates the Synergistic Activation of Human Cytochrome P-450 2C9 by the Constitutive Androstane Receptor and Hepatic Nuclear Factor-4α (2008) (39)
MICROBODIES IN EXPERIMENTALLY ALTERED CELLS : VII. CPIB-induced Hepatic Microbody Proliferation in the Absence of Significant Catalase Synthesis (1970) (39)
Peroxisomes: Biology and Role in Toxicology and Disease. Proceedings from an international symposium. Aspen, Colorado, June 28-July 2, 1995. (1996) (39)
Coactivator MED1 Ablation in Keratinocytes Results in Hair Cycling Defects and Epidermal Alternations (2011) (38)
Specific changes in the protein composition of rat liver in response to the peroxisome proliferators ciprofibrate, Wy-14,643 and di-(2-ethylhexyl)phthalate. (1985) (38)
Induction of Nuclear Translocation of Constitutive Androstane Receptor by Peroxisome Proliferator-activated Receptor α Synthetic Ligands in Mouse Liver* (2007) (38)
Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination (2016) (37)
MICROBODIES IN EXPERIMENTALLY ALTERED CELLS (1970) (37)
Serum triglyceride and cholesterol contents in male rats receiving diets containing plasticizers and analogues of the ester 2-ethylhexanol. (1982) (37)
Role of apoptosis in copper deficiency-induced pancreatic involution in the rat. (1993) (36)
Pancreatic hepatocytes. An in vivo model for cell lineage in pancreas of adult rat. (1991) (36)
Transdifferentiated hepatocytes in rat pancreas. (1986) (35)
Histogenesis of pseudo-ductular changes induced in the pancreas of guinea pigs treated with N-methyl-N-nitrosourea. (1980) (35)
Lack of covalent binding of peroxisome proliferators nafenopin and Wy-14 643 to DNA in vivo and in vitro. (1985) (34)
Peroxisome proliferator–activated receptor‐α−/− mice show enhanced hepatocyte proliferation in response to the hepatomitogen 1,4‐bis[2‐(3,5‐dichloropyridyloxy)] benzene, a ligand of constitutive androstane receptor (2001) (34)
Partial purification and immunoreactivity of an 80 000-molecular-weight polypeptide associated with peroxisome proliferation in rat liver. (1980) (34)
Hepatocyte growth factor/scatter factor-Met signaling induces proliferation, migration, and morphogenesis of pancreatic oval cells. (1996) (34)
Immunocytochemical localization of fatty acid metabolizing heat-stable and heat-labile enoyl-coenzyme A (CoA) hydratases in liver and renal cortex. (1983) (34)
Identification of promethin and PGLP as two novel up-regulated genes in PPARgamma1-induced adipogenic mouse liver. (2004) (34)
Carcinogenicity of peroxisome proliferators: evaluation and mechanisms. (1990) (33)
Loss of peroxisomal enzyme expression in preneoplastic and neoplastic lesions induced by peroxisome proliferators in rat livers. (1992) (33)
Reversible alteration of hepatic messenger RNA species for peroxisomal and non-peroxisomal proteins induced by the hypolipidaemic drug Wy-14,643. (1983) (33)
Rat urate oxidase produced by recombinant baculovirus expression: formation of peroxisome crystalloid core-like structures. (1992) (32)
Uric acid degrading enzymes, urate oxidase and allantoinase, are associated with different subcellular organelles in frog liver and kidney. (1994) (32)
Inhibition by Lasiocarpine of RNA Synthesis, RNA Polymerase and Induction of Tryptophan Pyrrolase Activity (1968) (32)
Induction of Hamster Hepatic Peroxisomal β-oxidation and Peroxisome Proliferation-associated 80000 mol. wt. Polypeptide by Hypolipidemic Drugs (1982) (32)
Induction of peroxisome proliferation and hepatic tumours in C57BL/6N mice by ciprofibrate, a hypolipidaemic compound. (1988) (32)
Hepatic peroxisome proliferation: induction by BR-931, a hypolipidemic analog of WY-14,643. (1978) (32)
Cloning and Identification of Rat Deoxyuridine Triphosphatase as an Inhibitor of Peroxisome Proliferator-activated Receptor α* (1996) (32)
Microbodies in experimentally altered cells. V. Histochemical and cytochemical studies on the livers of rats and acatalasemic (Csb) mice treated with CPIB. (1969) (31)
The Inflammatory Response in Acyl-CoA Oxidase 1 Deficiency (Pseudoneonatal Adrenoleukodystrophy) (2012) (30)
Hepatic Lipid Metabolism (2011) (30)
Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver. (2001) (29)
Mediator 1 Is Atherosclerosis Protective by Regulating Macrophage Polarization (2017) (29)
Immunocytochemical localization of urate oxidase, fatty acyl-CoA oxidase, and catalase in bovine kidney peroxisomes. (1988) (29)
Expression of transcription factors and stem cell factor precedes hepatocyte differentiation in rat pancreas. (1996) (29)
Transcriptional coactivator PRIP, the peroxisome proliferator-activated receptor gamma (PPARgamma)-interacting protein, is required for PPARgamma-mediated adipogenesis. (2003) (29)
Inhibition of spontaneous testicular Leydig cell tumor development in F-344 rats by dehydroepiandrosterone. (1992) (28)
Response of hepatocytes transplanted into syngeneic hosts and heterotransplanted into athymic nude mice to peroxisome proliferators. (1984) (28)
Localization of the human urate oxidase gene (UOX) to 1p22. (1992) (28)
Susceptibility of an ibred strain of guinea pigs to the induction of pancreatic adenocarcinoma by N-methyl-N-nitrosourea. (1974) (28)
Pancreatic necrosis and regeneration induced by 4-hydroxyaminoquinoline-1-oxide in the guinea pig. (1975) (28)
Overexpression and Characterization of the Human Peroxisomal Acyl-CoA Oxidase in Insect Cells (*) (1995) (28)
Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse (2009) (27)
Peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP) but not PPAR-interacting protein (PRIP) is required for nuclear translocation of constitutive androstane receptor in mouse liver. (2006) (27)
Induction of Hepatic Peroxisome Proliferation by Xenobiotics (1987) (27)
Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene (2009) (27)
Pathology of the liver in Reye's syndrome. (1975) (27)
Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. (2012) (27)
Peroxisome proliferator-activated receptor alpha-responsive genes induced in the newborn but not prenatal liver of peroxisomal fatty acyl-CoA oxidase null mice. (2001) (27)
Peroxisome proliferator-induced hepatocarcinogenesis: histochemical analysis of ciprofibrate-induced preneoplastic and neoplastic lesions for gamma-glutamyl transpeptidase activity. (1986) (26)
Med1 subunit of the mediator complex in nuclear receptor-regulated energy metabolism, liver regeneration, and hepatocarcinogenesis. (2014) (26)
Beckwith-Wiedemann syndrome. Wilms' tumor, cardiac hamartoma, persistent visceromegaly, and glomeruloneogenesis in a 2-year-old boy. (1972) (26)
Protein profiling of mouse livers with peroxisome proliferator-activated receptor alpha activation. (2004) (26)
Nuclear receptors and transcription factors in the development of fatty liver disease. (2012) (26)
Immunocytochemical localization of liver-specific proteins in pancreatic hepatocytes of rat. (1988) (26)
Noninhibitory effect of antioxidants ethoxyquin, 2(3)-tert-butyl-4-hydroxyanisole and 3,5-di-tert-butyl-4-hydroxytoluene on hepatic peroxisome proliferation and peroxisomal fatty acid beta-oxidation induced by a hypolipidemic agent in rats. (1983) (25)
Differentiation of pancreatic acinar carcinoma cells cultured on rat testicular seminiferous tubular basement membranes. (1984) (25)
Comparison of the Peroxisome Proliferator-Induced Pleiotropic Response in the Liver of Nine Strains of Mice (1989) (25)
Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice (2016) (25)
Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system. (2003) (25)
Pigment epithelium-derived factor is an angiogenesis and lipid regulator that activates peroxisome proliferator-activated receptor alpha. (2008) (24)
Elevated hepatocyte levels of the Forkhead box A2 (HNF‐3β) transcription factor cause postnatal steatosis and mitochondrial damage (2003) (24)
Differentiation and DNA synthesis in pancreatic acinar carcinoma of rat. (1980) (24)
Peroxisome proliferator-induced hepatocarcinogenesis: levels of activating and detoxifying enzymes in hepatocellular carcinomas induced by ciprofibrate. (1987) (24)
Polyribosome disaggregation in rat liver following administration of tannic acid. (1970) (24)
Tumorigenic conversion of a non‐tumorigenic rat urothelial cell line by overexpression of H2O2‐generating peroxisomal fatty acyl‐CoA oxidase (1997) (23)
Dehydroepiandrosterone-Induced Peroxisome Proliferation in the Rat: Evaluation of Sex Differences (1994) (23)
Hepatic effects of some [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (WY-14,643) analogs in the mouse. (1977) (23)
Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4 (2015) (23)
Targeted Disruption of the Peroxisomal Fatty Acyl‐CoA Oxidase Gene: Generation of a Mouse Model of Pseudoneonatal Adrenoleukodystrophy a (1996) (22)
Peroxisome proliferator-activated receptor-α signaling in hepatocarcinogenesis. (2013) (22)
Microbody (Peroxisome) proliferation in mouse kidney induced by methyl clofenapate (1975) (22)
Comparison of secretory protein and membrane composition of secretory granules isolated from normal and neoplastic pancreatic acinar cells of rats. (1983) (22)
Microbodies in experimentally altered cells. IX. The fate of microbodies. (1972) (22)
Coexpression of glutamine synthetase and carbamoylphosphate synthase I genes in pancreatic hepatocytes of rat. (1990) (22)
Induction of malignant vascular tumors of the liver in guinea pigs treated with 2,2'-dihydroxy-di-n-propylnitrosamine. (1977) (21)
Transplantable acinar cell carcinoma of the rat pancreas. (1979) (21)
The Med1 Subunit of the Mediator Complex Induces Liver Cell Proliferation and Is Phosphorylated by AMP Kinase* (2013) (21)
Estradiol receptor assays in normal and neoplastic tissues. A possible diagnostic acid for tumor differentiation. (1979) (21)
Purification, properties, and immunocytochemical localization of human liver peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. (1987) (21)
Induction of peroxisomal enzymes in livers of neonatal rats exposed to lactating mothers treated with hypolipidaemic drugs. Role of drug metabolite transfer in milk. (1983) (20)
Xenobiotic-induced peroxisome proliferation: role of tissue specificity and species differences in response in the evaluation of the implications for human health. (1987) (20)
Rapid development of hyperplastic nodules and cirrhosis in the liver of rats treated concurrently with thioacetamide and the pyrrolizidine alkaloid lasiocarpine (1976) (20)
Alteration of Skin Wound Healing in Keratinocyte-Specific Mediator Complex Subunit 1 Null Mice (2014) (20)
Pancreatic hepatocytes (1991) (20)
Peroxisome proliferator-induced alterations in the expression and modification of rat hepatocyte plasma membrane proteins. (1990) (20)
The relevance of peroxisome proliferation and cell proliferation in peroxisome proliferator-induced hepatocarcinogenesis. (1989) (20)
An in vitro demonstration of peroxisome proliferation and increase in peroxisomal β‐oxidation system mRNAs in cultured rat hepatocytes treated with ciprofibrate (1989) (20)
Increased expression of sulfated glycoprotein-2 and DNA fragmentation in the pancreas of copper-deficient rats. (1994) (19)
An upstream region of the enoyl-coenzyme A hydratase/3-hydroxyacyl-coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice. (1994) (19)
Phenotypic Properties of Liver Tumors Induced by Dehydroepiandrosterone in F‐344 Rats (1992) (19)
Induction of peroxisome proliferation in hepatocytes transplanted into the anterior chamber of the eye. A model system for the evaluation of xenobiotic-induced effects. (1986) (19)
Hepatic megalocytosis in chronic lasiocarpine poisoning. Some functional studies. (1971) (18)
Roles of MED1 in quiescence of hair follicle stem cells and maintenance of normal hair cycling. (2013) (18)
Role of AMACR (α-methylacyl-CoA racemase) and MFE-1 (peroxisomal multifunctional enzyme-1) in bile acid synthesis in mice. (2014) (18)
Transcriptional and Translational Modulation of myo-Inositol Oxygenase (Miox) by Fatty Acids (2015) (18)
Immunohistochemical localization of pancreatic exocrine enzymes in normal and neoplastic pancreatic acinar epithelium of rat. (1981) (17)
Effect of peroxisome proliferators on intrachromosomal and interchromosomal recombination in yeast. (1990) (17)
Theme Lipid Metabolism and Liver Inflammation . II . Fatty liver disease and fatty acid oxidation (2006) (17)
The nucleotide sequence of a full length cDNA clone encoding rat liver urate oxidase. (1989) (17)
1-methyl-4piperidyl-bis (P-chlorophenoxy) acetate: a new hypolipidemic peroxisome proliferator. (1975) (17)
Microbody (Peroxisome) matrix: Transformation into tubular structures (1973) (16)
Alterations of pancreatic hepatocytes in rats exposed to carcinogens. (1991) (16)
Some Effects of Chemical Carcinogens on Cell Organelles (1975) (16)
Ciprofibrate represses α2u-globulin expression in liver and inhibits d-limonene nephrotoxicity (1996) (16)
Formation of ductular structures in vitro by rat pancreatic epithelial oval cells. (1993) (16)
Profiling of acyl-CoA oxidase-deficient and peroxisome proliferator Wy14,643-treated mouse liver protein by surface-enhanced laser desorption/ionization ProteinChip Biology System. (2002) (16)
Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase. (1998) (16)
ERK2-Mediated Phosphorylation of Transcriptional Coactivator Binding Protein PIMT/NCoA6IP at Ser298 Augments Hepatic Gluconeogenesis (2013) (16)
Polyribosome disaggregation in rat liver by lasiocarpine. (1969) (15)
Differentiation and cell proliferation patterns in rat exocrine pancreas: role of type I and type II injury. (1990) (15)
Concanavalin A agglutinability and surface microvilli of dissociated normal and neoplastic pancreatic acinar cells of the rat. (1979) (15)
Peroxisome development in the regenerating pars recta (P3 segment) of proximal tubules of the rat kidney. (1976) (15)
Increased peroxisomal activity in the liver of vitamin E deficient rats (1981) (15)
Deletion of a Malaria Invasion Gene Reduces Death and Anemia, in Model Hosts (2011) (15)
Functional expression and peroxisomal targeting of rat urate oxidase in monkey kidney cells. (1995) (15)
Pancreatic acinar cell regeneration following copper deficiency-induced pancreatic necrosis (1986) (15)
PANCREATIC BIOTINIDASE ACTIVITY: THE POTENTIAL FOR INTESTINAL PROCESSING OF DIETARY PROTEIN-BOUND BIOTIN (1984) (15)
Nuclear receptor transcriptional coactivators in development and metabolism (2006) (14)
Carbamylcholine stimulation of protein secretion in pancreatic acinar carcinoma of rat. (1982) (14)
Transcription coactivator PRIP, the peroxisome proliferator-activated receptor (PPAR)-interacting protein, is redundant for the function of nuclear receptors PParalpha and CAR, the constitutive androstane receptor, in mouse liver. (2006) (14)
Neoplasia and chronic disease associated with the prolonged administration of dehydroheliotridine to rats. (1983) (14)
Expression and compartmentalization of integral plasma membrane proteins by hepatocytes and their progenitors in the rat pancreas. (1991) (14)
Interstitial Cell Tumor, Testis, Rat (1987) (14)
PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex (2010) (14)
Immunocytochemical Study of the Ultrastructure of Peroxisomes and the Effects of Peroxisome Proliferators a (1996) (14)
Comparative effects of dehydroepiandrosterone and related steroids on peroxisome proliferation in rat liver. (1993) (14)
Increased peroxisomal enzyme mRNA levels in adult rat hepatocytes cultured in a chemically defined medium and treated with nafenopin. (1988) (13)
Duct-like morphogenesis of Longnecker pancreatic acinar carcinoma cells maintained in vitro on seminiferous tubular basement membranes. (1986) (13)
In vivo distribution of a carcinogenic hepatic peroxisome proliferator: whole-body autoradiography of [14C]ciprofibrate in the mouse. (1989) (13)
Di-(2-ethylhexyl)phthalate: an industrial plasticizer induces hypolipidemia and enhances hepatic catalase and carnitine acetyltransferase activities in rat and mice. (1976) (13)
Brief Communication: Laslocarplne-Induced, Transplantable Squamous Cell Carcinoma of Rat Skin (1974) (12)
Hepatic Catalase Is Not Essential for the Hypolipidemic Action of Peroxisome Proliferators 1 (1977) (12)
The ultrastructural effects of aflatoxin B1 in the rat pancreas (1975) (12)
Mutagenicity of the pyrrolizidine (Senecio) alkaloid, lasiocarpine in the Salmonella/microsome test (1978) (12)
Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPARγ and Identification of TUSC5 Coding Variants in Lean and Obese Humans (2010) (12)
Hepatic Peroxisome Proliferation: An Overview (1988) (12)
Functional expression of rat peroxisomal acyl-CoA oxidase in Spodoptera frugiperda cells. (1994) (12)
Expression of peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase enzyme and its mRNA in peroxisome proliferator-induced liver tumors. (1994) (12)
Secretion granules of transplantable pancreatic acinar carcinoma of rat. (1980) (12)
Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα (2010) (12)
Carcinogenicity of 2,2'-dihydroxy-di-n-propylnitrosamine in the tree shrew (Tupaia glis): light and electron microscopic features of pulmonary adenomas. (1980) (12)
TRANSCRIPTIONAL AND TRANSLATIONAL MODULATION OF MYO-INOSITOL OXYGENASE (MIOX) BY FATTY ACIDS: IMPLICATIONS IN RENAL TUBULAR INJURY INDUCED IN OBESITY AND DIABETES (2015) (12)
Natural segregation of nucleolar components of liver cells in newts. (1972) (12)
662 – STRUCTURE-ACTIVITY RELATIONSHIPS OF CLOFIBRATE-LIKE COMPOUNDS ON LIPID METABOLISM (1977) (12)
Peroxisome-associated enzymes and serum lipids in tumour-bearing rats treated with peroxisome-proliferating agents. (1984) (12)
Induction by ciprofibrate of hepatic peroxisome proliferation in rats, pigeons, chickens, cats and rhesus monkeys (1982) (11)
Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members. (2007) (11)
Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin. (1995) (11)
Testicular feminization of the mouse: paucity of peroxisomes in Leydig cell of the testis. (1981) (11)
Phenotypic Properties of Preneoplastic and Neoplastic Hepatic Lesions Induced by Peroxisome Proliferators in Rats (1987) (10)
Antidiabetic Activity of Ethanolic Extract of Hydnocarpus Wightiana Blume Using Stz Induced Diabetes in Sd Rats (2013) (10)
Are acinar cells involved in the pathogenesis of ductal adenocarcinoma of the pancreas? (1991) (10)
Separation and characterization of neoplastic cell subpopulations of a transplantable rat pancreatic acinar carcinoma. (1982) (10)
Pancreatic regeneration caused by ethionine in the guinea pig. (1974) (10)
gamma-Glutamyltranspeptidase-negative phenotypic property of preneoplastic and neoplastic liver lesions induced by ciprofibrate does not change following 2-acetylaminofluorene administration. (1989) (10)
Excessive lipofuscin accumulation in the thyroid gland in mucoviscidosis. (1973) (10)
Lack of expression of glutathione-S-transferase P, gamma-glutamyl transpeptidase, and alpha-fetoprotein messenger RNAs in liver tumors induced by peroxisome proliferators. (1988) (10)
Mutational Analysis of the Putative Copper‐binding Site of Rat Urate Oxidase a (1996) (10)
Proliferation of microbodies and synthesis of catalase in rat liver. Induction in tumor-bearing host by CPIB. (1971) (10)
Androgen regulated expression of the alpha 2u-globulin gene in pancreatic hepatocytes of rat (1990) (9)
Isolation and ultrastructure of nucleoli altered in vivo. (1968) (9)
Transplantable pancreatic acinar carcinoma (1981) (9)
PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism (2018) (9)
Induction and differentiation of exocrine pancreatic tumors in the rat. (1985) (9)
Intracellular transport and storage of secretory proteins in relation to cytodifferentiation in neoplastic pancreatic acinar cells (1983) (9)
IMMUNOCYTOCHEMICAL LOCALIZATION OF CATALASE, HEAT‐LABILE ENOYL‐CoA HYDRATASE, AND POLYPEPTIDE PPA‐80 IN RAT LIVER * (1982) (8)
Laslocarpine-induced, transplantable squamous cell carcinoma of rat skin. (1974) (8)
Induction of hepatic ornithine decarboxylase by hypolipidemic drugs with hepatic peroxisome proliferative activity. (1981) (8)
1 Adipocyte-specific Gene Expression and Adipogenic Steatosis in the Mouse Liver due to PPAR γ 1 Overexpression * (2002) (8)
Tannic acid-induced nucleolar changes in hepatocytes transplanted into syngeneic or xenogeneic host and in hepatocytes maintained in primary culture. (1987) (8)
Effect of lasiocarpine on aflatoxin B 1 carcinogenicity in rat liver. (1972) (8)
Progress in pancreatic cancer: implications of phenotypic and molecular plasticity. (1995) (7)
Degradation kinetics of liver catalase in rats treated with ethyl-alpha-p-chlorophenoxyisobutyrate. (1971) (7)
The effect of cycloheximide on ribonucleic acid and protein synthesis in rat liver. (1969) (7)
Pathology of tumors developed in guinea pigs given intraperitoneal injections of N-methyl-N-nitrosourea. (1977) (7)
Demonstration of kallikrein in a rat pancreatic acinar cell carcinoma. (1985) (7)
Concanavalin A binding and cytodifferentiation in pancreatic acinar carcinoma of rat. (1982) (7)
Med1 regulates meiotic progression during spermatogenesis in mice. (2015) (7)
Rat urate oxidase: cloning and structural analysis of the gene and 5'-flanking region. (1991) (7)
The effect of microvesicular fatty change on liver regeneration after partial hepatectomy. (2000) (6)
Ciprofibrate represses alpha 2u-globulin expression in liver and inhibits d-limonene nephrotoxicity. (1996) (6)
Immunocytochemical localization of exocrine enzymes in rat pancreatic acinar carcinoma. (1984) (6)
Multinucleate giant cells in livers of marmosets given aflatoxin B1. (1971) (6)
Experimental Carcinogenesis of Exocrine Pancreas: Animal Models, Neoplasms, and Current Understanding of Pathogenesis (1985) (6)
Effect of Calorie Restriction on the Fate of Hyperplastic Liver Nodules Induced by Concurrent Administration of Lasiocarpine and Thioacetamide (1983) (6)
Correction: Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice (2016) (5)
Increased resistance of peroxisome proliferator-induced hepatic lesions to iron overload in rats. (1986) (5)
Plasma membrane retrieval in neoplastic pancreatic acinar cells. (1983) (5)
www.cognizantcommunication.com Identification of Novel Peroxisome Proliferator-Activated Receptor α (PPAR α ) Target Genes in Mouse Liver Using cDNA Microarray (2001) (5)
Computerized tomography and ultrasound in the diagnosis of cerebro-hepato-renal syndrome of Zellweger (1987) (5)
Abstract 492: Hepatic oxidative stress activates the Gadd45b gene via degradation of the transcriptional repressor STAT3 (2014) (5)
Alteration of a membrane associated marker in transplantable rat pancreatic acinar cell carcinoma. (1984) (5)
Peroxisome Proliferation-Related Oxidative Stress and Hepato-Carcinogenesis (1987) (5)
Purification and characterization of α-amylase from rat pancreatic acinar carcinoma: comparison with pancreatic α-amylase (1987) (5)
Replicative culture in vitro of pancreatic epithelial oval cells derived from rats after copper deficiency-induced acinar cell depletion (1991) (5)
Myosin from pancreatic acinar carcinoma cells. Isolation, characterization and demonstration of heavy- and light-chain phosphorylation. (1987) (5)
Pancreatic stem cells (2007) (5)
Mice lacking transcription cofactor PRIC285 reveal attenuation of liver regeneration but are viable and develop normally (2009) (5)
Incorporation of [35S]sulfate in normal and neoplastic rat pancreatic acinar cells in relationship to cytodifferentiation. (1984) (4)
Trimethylguanosine synthase 1 is a novel regulator of pancreatic beta-cell mass and function (2022) (4)
Stimulation of liver catalase synthesis in rats by ethyl-alpha-p-chlorophenoxyisobutyrate. (1971) (4)
Absence of increased carnitine acetyltransferase activity in the liver with proliferation of smooth endoplasmic reticulum. (1977) (4)
Peroxisome proliferator-activated receptor alpha-dependent induction of cell surface antigen Ly-6D gene in the mouse liver. (2001) (4)
Mouse Cardiac Pde1C Is a Direct Transcriptional Target of Pparα (2018) (4)
Cloning and identification of rat deoxyuridine triphosphatase as an inhibitor of peroxisome proliferator-activated receptor alpha. (1996) (4)
Hepatic ultrastructure and adaptation. (1987) (4)
Erratum: Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene (Journal of Biological Chemistry (1996) 271 (2147-2155)) (1998) (4)
Isolation of PBP165 as a cofactor of peroxisome proliferator activated receptor(PPAR)gamma (1997) (4)
Identification of cytosolic peroxisome proliferator binding protein as a member of the heat shock protein HSP 70 family ( peroxisomes / drug-binding protein ) (4)
MICROBODIES IN EXPERIMENTALLY ALTERED CELLS (1969) (4)
CHAPTER 19 – Some Effects of Carcinogens on the Structure and Activity of Liver Cells (1970) (4)
Metaplastic Transformation of Pancreatic Cells to Hepatocytes (1989) (3)
Modulation of the phenotypic expression of rat hepatocyte nodules hn by a hypolipidemic agent ciprofibrate cf (1987) (3)
Absence of gamma-glutamyltranspeptidase activity in lung metastasis in rats with hepatocellular carcinomas induced by ciprofibrate, a peroxisome proliferator. (1987) (3)
Estradiol receptors in the transplantable pancreatic carcinoma of the rat (1978) (3)
A comparative study of the effects of clofibrate, ciprofibrate, WY-14,643, and di-(2-ethylhexyl)-phthalate on liver protein expression in mice. (1991) (3)
themes Nonalcoholic Steatosis and Steatohepatitis III. Peroxisomal b -oxidation, PPAR a , and steatohepatitis (2001) (3)
Amphibian Catalase: Cloning, Tissue Distribution, and Peroxisomal Localization (1996) (3)
Purification and characterization of alpha-amylase from rat pancreatic acinar carcinoma. Comparison with pancreatic alpha-amylase. (1987) (3)
Foreword (1996) (3)
Cloning and expression of the mouse deoxyuridine triphosphate nucleotidohydrolase gene: differs from the rat enzyme in that it lacks nuclear receptor interacting LXXLL motif. (1999) (2)
Induction of hepatic peroxisomes, peroxisome associated enzymes and hypolipidemia in rats treated with 2 ethyl hexanoic acid and 2 ethyl hexanol (1976) (2)
Localization of carbamylphosphate synthetase (ammonia) (CPS) in pancreatic hepatocytes of rat (1985) (2)
Transcription coactivator PBP/MED1 regulates hepatocyte size and hepatocellular regeneration in the mouse (2006) (2)
Morphometric analysis of ultrastructural changes in rat liver induced by peroxisome proliferators (1975) (2)
Tissue specificity in the induction of peroxisome proliferation-associated polypeptide (PPA-80) and peroxisomal β-oxidation in rats by ciprofibrate (1985) (2)
4 Hydroxyaminoquinoline 1 oxide induced pancreatic necrosis and regeneration in the guinea pig: ultrastructural and autoradiographic studies (1975) (2)
Rous-Whipple Award Lecture Peroxisome Proliferators and Peroxisome Proliferator-Activated Receptor (cid:1) Biotic and Xenobiotic Sensing (2004) (2)
Hepatocarcinogenicity of wy-14,643, a hypolipidemic peroxisome proliferator. Abstr. (1978) (2)
Comparative effects of hypolipidemic drugs on hepatic peroxisomal enzymes (1976) (2)
Erratum: Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα (Laboratory Investigation (2010) 90 (696-708) DOI: 10.1038/labinvest.2010.46) (2010) (2)
Production in vivo of falloff monosomes in mouse liver by sparsomycin. (1977) (2)
Testicular Feminization, Testes, and Testicular Tumors, Rat, Mouse (1987) (2)
Bipotential stem cells in the rat pancreas (1994) (2)
32P-postlabeling (32P) analysis of DNA adduct formation with carcinogenic peroxisome proliferators (1985) (1)
Binding of labeled N-methyl N-nitrosourea to macromolecules of squamous and glandular stomach of rats. (1976) (1)
Acyl‐CoA Oxidase, Peroxisomal (2002) (1)
Ethyl-α-p-chlorophenoxyisobutyrate induced hepatic microbody proliferation in rat liver and ubiquinone concentration (1971) (1)
Peroxisome proliferation and hepatocarcinogenesis. (1987) (1)
Some Effects of Carcinogens on Cell Organelles (1982) (1)
Investigational strategies for detection and intervention in early-stage pancreatic cancer (1994) (1)
Increased lipid peroxidation in the rat liver following induction of peroxisome proliferation (1985) (1)
Chronic Pancreatic Toxicity ‚Äî Role of Stem Cells in the Conversion of Pancreas to Liver (2005) (1)
Sub cellular changes in exocrine pancreas of the guinea pig induced by azaserine (1976) (1)
Secretion Granules ofTransplantable Pancreatic Acinar Carcinoma ofRat (1980) (1)
Isolation of Granule-Rich and Granule-Deficient Cell Populations from Acinar Carcinoma of Rat Pancreas (1987) (1)
Regeneration of the Guinea Pig Parotid Gland after 4-hydroxyaminoquinoline-1-oxide-lnduced Necrosis (1976) (1)
Peroxisome Proliferation: A Biological Marker for Toxicological Evaluation (1992) (1)
Testicular feminization of the mouse: reduction of peroxisome population in Leydig cells of the testis (1975) (1)
HISTOCHEMISTRY OF PEROXISOMES : OVERVIEW (1995) (1)
Transcriptional regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators (catalase/fatty acid .-oxidation/dofibrate/ciprofibrate/bis(2-ethylhexyl) phthalate) (2016) (0)
In MemoriamIn Memoriam (1999) (0)
Aflatoxin B1 induced liver tumors in Tupaia glis (tree shrews), a nonhuman primate (1975) (0)
Damage by Peroxisome Proliferators of the Molecular Source of Radicals Responsible for DNA Chemical-induced Chronic Oxidative Stress : Identification Detection of in Vivo Sensitive Biomarker for Expression of Base Excision DNA Repair Genes Is a (2004) (0)
Response of Chemically Induced Hepatocytelike Cells Hamster Pancreas to Methyl Clofenapate, A Peroxisome Proliferator in M. SAMBASIVA RAO, M. KUMUDAVALLI REDDY, JANARDAN K. REDDY.. and DANTE G. SCARPELLI (2003) (0)
Transcription coactivator PBP/MED1 deficiency prevents dexamethasone‐induced fatty liver (2006) (0)
Peroxisomal enzyme changes in mouse kidney induced by methyl-2-[4-(p-chlorophenyl)-phenoxy]-2-methylpropionate (1980) (0)
The effect of cyclopropenoid fatty acids on binding of aflatoxin B1 to nuclear DNA, RNA and protein of rat hepatocytes (1975) (0)
Expression of protein, P24 in two transplantable pancreatic cancer carcinomas (PACA) of rat (1985) (0)
Isolation and sequence determination of a cDNA clone for rat peroxisomal urate oxidase : Liver-specific expression in the rat ( tissue specificity / peroxisome proliferators / primer extension ) (0)
Incorporation of [ 35 S ] Sulfate in Normal and Neoplastia Rat Pancreatic Acinar Cells in Relationship to Cytodifferentiation 1 (2006) (0)
Transcription coactivator PRIP is not essential for the function of nuclear receptors CAR and PPARα in liver (2006) (0)
Nafenopin: A hypolipidemic hepatic peroxisome proliferator that induces hepatocellular carcinomas in mice (1976) (0)
Pancreatic lesions caused by ethionine or N methyl N nitrosourea in the guinea pig (1973) (0)
Inductionof Liver Tumorsby Aflatoxin B1in the Tree Shrew (Tupalagus), a NonhumanPrimate1 (1976) (0)
Hepatocarcinogenicity of Dehydroepiandrosterone in the Rat 1 (2006) (0)
Title The peroxisomal enzyme L-PBE is required to preventthe dietary toxicity of medium-chain Fatty acids (2017) (0)
Induction of peroxisome proliferation and peroxisomal beta oxidation system messenger rna levels by ciprofibrate in primary cultures of dog hepatocytes (1989) (0)
Hemophilia a presenting with quadriparesis, a rare clinical presentation (2016) (0)
Malignant Tumors in Rats Given Lasiocarpine 1 (2006) (0)
Cloning and Identification o f M ouse Steroid Receptor C oactivator-1 (mSRC-1), as a Coactivator o f Peroxisom e Proliferator-Activated Receptor y (2016) (0)
Gene expression for peroxisome-associated enzymes in hepatocellular carcinomas induced by ciprofibrate, a hypolipidemic compound (1986) (0)
Abstract 1248: Critical Role of Peroxisome Proliferator-Activated Receptor Binding Protein in the Heart (2007) (0)
Comparative study of the induction of hepatic peroxisomes and associated enzymes by a hypolipidemic drug and phthalate-ester plasticizers in Fisher 344 rats (1984) (0)
Overexpression of PPAR (cid:68) regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D- forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal (cid:69) -oxidation system* (2003) (0)
Transcription coactivator PBP/MED1 is required for diethylnitrosamine‐induced hepatocarcinogenesis in the mouse (2009) (0)
ANTI DIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF Aconitum Ferox IN ALLOXAN INDUCED DIASEASED RATS (2016) (0)
TGS1: a novel regulator of β-cell mass and function (2021) (0)
Preparation of recombinant adenoviruses of PPARγ and its transcriptional coactivator MED1 and their biological function analysis (2015) (0)
Transcriptional Regulation of Cidea in mouse liver by PPAR {alpha} and PPAR{gamma} (2006) (0)
Development of hepatocellular carcinoma in mice with disrupted peroxisomal fatty acyl-CoA oxidase gene (1997) (0)
THE RELEVANCE OF PEROXISOME PROLIFERATION AND CELL PROLIFERATION HEPATOCARCINOGENESIS* IN PEROXISOME PROLIFERATOR4NDUCED (1989) (0)
Pancreatic Involution in the Rat (2007) (0)
Med1 subunit of the mediator complex is phosphorylated by AMPK (2013) (0)
Two-dimensional polyacrylamide gel electrophoretic analysis of [35S]methionine (35S-Met) labeled hepatocyte proteins reveals rapid induction of specific proteins by ciprofibrate, a peroxisome proliferator (1985) (0)
Induction of liver tumours by 3'-methyl-dimethylaminoazobenzene (3'-Me-DAB) in rats chronically infected with Toxoplasma or Besnoitia. (1977) (0)
Purification , properties , and immunocytochemical localization of human liver peroxisomal enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase ( fatty acid 13-oxidation / electron microscopy / rotary shadowing ) (0)
Transformation of mammalian cells by overexpressing H 202-generating peroxisomal fatty acyl-CoA oxidase ( peroxisome proliferation / peroxisome proliferators / fatty acid a-oxidation ) (0)
Reye's syndrome: report of cases and a review of literature. (1975) (0)
Inductionand Originof Hepatocytes inRat Pancreas (2013) (0)
Differential expression of nuclear receptor coregulators in mouse tissues (2006) (0)
[Hyperlipidemia in hepatic MED1 deficient mice in response to fasting]. (2011) (0)
Toxicological Implications of Peroxisome Proliferation (2020) (0)
Angiosarcoma of the liver in guinea pigs induced by 2,2'-dihydroxy-di-N-propylnitrosamine: light and electron microscopic features (1977) (0)
Perspective on hepatic peroxisomes and pancreatic hepatocytes (1994) (0)
Peroxisome proliferator ciprofibrate inhibits the induction in rat liver of glutathione S-transferase activity by the antioxidant ethoxyqui (1984) (0)
Quantitation of bovine liver catalase by single radial immunodiffusion. (1974) (0)
Informal Discussion following the Paper by Reddy and Rao (1975) (0)
Tissue distribution of peroxisome proliferator-activated receptor in the mouse (1994) (0)
Increased resistance of peroxisome proliferator induced hepatic lesions to iron accumulation in rats (1985) (0)
Quantitative changes in sets of proteins as markers of biological response. (1991) (0)
PPAEα in the pathogenesis of fatty liver disease (2004) (0)
Erratum: Transcription coactivator PBP, the peroxisome proliferator- activated receptor (PPAR)-binding protein, is required for PPARα-regulated gene expression in liver (Journal of Biological Chemistry (2004) 279 (24427-24434)) (2004) (0)
Thioacetamide enhances development of neoplastic nodules and cirrhosis in the liver of rats fed lasiocarpine, a pyrrolizidine alkaloid (1976) (0)
Transcriptional Regulation of Cidea in mouse liver by PPAR α and PPARγ (2006) (0)
Separation and Characterization of Neoplastic Cell Subpopulations of a Transplantable Rat Pancreatic Acinar Carcinoma 1 (2006) (0)
Stable Expression of Peroxisomal Fatty Acyl‐CoA Oxidase in Vitro a (1996) (0)
Induction ofperoxisome proliferation andhepatic tumoursin C57BL/6Nmicebyciprofibrate, a hypolipidaemic compound (1988) (0)
Mechanistic relevance of peroxisome proliferation to human cancer risk assessment (1998) (0)
PAT5A: A partial agonist of PPARγ is a potent antidiabetic thiazolidinedione yet weakly adipogenic (2003) (0)
Stimulation of catalase and carnitine acetyltransferase activities and peroxisome proliferation by 1 methyl 4 piperidyl bis (p chlorophenoxy) acetate (1975) (0)
The Role of PRIP in Breast Cancer (2002) (0)
Tra nspla n table Pan c rea tic A cin a r Ca rcin om a (1981) (0)
Dose dependent increase of hepatic catalase and carnitine acetyltransferase activities in intact female rats fed clofibrate (1978) (0)
Localization and Expression of the Eicosanoid Metabolizing P4501VA Gene Family in Rat Tissues and Hepatic Tumors (1991) (0)

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What Schools Are Affiliated With Janardan K. Reddy?

Janardan K. Reddy is affiliated with the following schools:

Northwestern University