Janardan K. Reddy
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Janardan K. Reddymedical Degrees
Medical
#1041
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#1336
Historical Rank
Pharmacology
#75
World Rank
#98
Historical Rank

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Janardan K. Reddy's Degrees
- PhD Pharmacology University of California, San Francisco
- Doctorate Medicine University of California, San Francisco
Why Is Janardan K. Reddy Influential?
(Suggest an Edit or Addition)Janardan K. Reddy's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors (2006) (946)
- Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. (1996) (906)
- Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens (1980) (835)
- PEROXISOMAL β-OXIDATION AND PEROXISOME PROLIFERATOR–ACTIVATED RECEPTOR α: An Adaptive Metabolic System (2001) (804)
- Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation. (2006) (781)
- Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoforms. (1995) (673)
- Adipocyte-specific Gene Expression and Adipogenic Steatosis in the Mouse Liver Due to Peroxisome Proliferator-activated Receptor γ1 (PPARγ1) Overexpression* (2003) (531)
- Application of comparative functional genomics to identify best-fit mouse models to study human cancer (2004) (458)
- Defect in Peroxisome Proliferator-activated Receptor α-inducible Fatty Acid Oxidation Determines the Severity of Hepatic Steatosis in Response to Fasting* (2000) (435)
- Peroxisomal lipid metabolism. (1994) (425)
- Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. (1993) (376)
- Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system. (2001) (372)
- Steatohepatitis, Spontaneous Peroxisome Proliferation and Liver Tumors in Mice Lacking Peroxisomal Fatty Acyl-CoA Oxidase (1998) (346)
- Isolation and Characterization of PBP, a Protein That Interacts with Peroxisome Proliferator-activated Receptor* (1997) (345)
- Hepatic peroxisome proliferation: induction by two novel compounds structurally unrelated to clofibrate (1975) (336)
- Carcinogenesis by hepatic peroxisome proliferators: evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. (1983) (324)
- Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression. (2006) (320)
- Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators. (1986) (312)
- Peroxisome proliferation and hepatocarcinogenesis. (1987) (304)
- Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. (2003) (293)
- Activation of flavin-containing oxidases underlies light-induced production of H2O2 in mammalian cells. (1999) (285)
- PPARα: energy combustion, hypolipidemia, inflammation and cancer (2010) (248)
- Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator. (1989) (247)
- Hepatocellular and Hepatic Peroxisomal Alterations in Mice with a Disrupted Peroxisomal Fatty Acyl-coenzyme A Oxidase Gene* (1996) (243)
- Identification of toxicologically predictive gene sets using cDNA microarrays. (2001) (238)
- Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. (1992) (238)
- Transcription coactivators for peroxisome proliferator-activated receptors. (2007) (237)
- HEPATIC AND RENAL EFFECTS OF PEROXISOME PROLIFERATORS: BIOLOGICAL IMPLICATIONS * (1982) (227)
- Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis. (2000) (224)
- Hepatic peroxisome (microbody) proliferation in rats fed plasticizers and related compounds. (1978) (218)
- Peroxisomal and Mitochondrial Fatty Acid β-Oxidation in Mice Nullizygous for Both Peroxisome Proliferator-activated Receptor α and Peroxisomal Fatty Acyl-CoA Oxidase (1999) (204)
- Identification of a Peroxisome Proliferator-responsive Element Upstream of the Human Peroxisomal Fatty Acyl Coenzyme A Oxidase Gene (*) (1996) (204)
- Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator, [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14, 643), in rat and mouse liver. (1979) (200)
- Oxidative DNA damage caused by persistent peroxisome proliferation: its role in hepatocarcinogenesis. (1989) (197)
- III. Peroxisomal β-oxidation, PPARα, and steatohepatitis (2001) (196)
- Isolation and Characterization of Peroxisome Proliferator-activated Receptor (PPAR) Interacting Protein (PRIP) as a Coactivator for PPAR* (2000) (195)
- Excessive accumulation of autofluorescent lipofuscin in the liver during hepatocarcinogenesis by methyl clofenapate and other hypolipidemic peroxisome proliferators. (1982) (192)
- Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma. (1996) (192)
- Coactivators in PPAR-Regulated Gene Expression (2010) (185)
- Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer. (1999) (184)
- Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor alpha to Wy-14,643-induced liver tumorigenesis. (2006) (179)
- Peroxisome proliferator-activated receptors, coactivators, and downstream targets (2007) (177)
- Peroxisome proliferator-activated receptors, fatty acid oxidation, steatohepatitis and hepatocarcinogenesis. (2003) (172)
- Peroxisomal β-Oxidation and Steatohepatitis (2001) (167)
- Hepatocellular carcinomas in acatalasemic mice treated with nafenopin, a hypolipidemic peroxisome proliferator. (1976) (165)
- Properties of hypolipidemic peroxisome proliferators in the lymphocyte [3H]thymidine and Salmonella mutagenesis assays. (1980) (164)
- Comparison of constitutive and inducible levels of expression of peroxisomal beta-oxidation and catalase genes in liver and extrahepatic tissues of rat. (1988) (157)
- Tumorigenicity of the hypolipidaemic peroxisome proliferator ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) in rats. (1979) (148)
- Malignant tumors in rats fed nafenopin, a hepatic peroxisome proliferator. (1977) (148)
- Induction of hepatic peroxisome proliferation in nonrodent species, including primates. (1984) (145)
- HYPOLIPIDEMIC HEPATIC PEROXISOME PROLIFERATORS FORM A NOVEL CLASS OF CHEMICAL CARCINOGENS (1980) (144)
- Peroxisome proliferation and lipid peroxidation in rat liver. (1986) (143)
- Deletion of PBP/PPARBP, the Gene for Nuclear Receptor Coactivator Peroxisome Proliferator-activated Receptor-binding Protein, Results in Embryonic Lethality* (2000) (139)
- Identification of a transcriptionally active peroxisome proliferator-activated receptor α-interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator (2002) (134)
- Evaluation of Selected Hypolipidemic Agents for the Induction of Peroxisomal Enzymes and Peroxisome Proliferation in the Rat Liver (1983) (133)
- Defects of the Heart, Eye, and Megakaryocytes in Peroxisome Proliferator Activator Receptor-binding Protein (PBP) Null Embryos Implicate GATA Family of Transcription Factors* (2002) (126)
- Di-(2-ethylhexyl)phthalate: An industrial plasticizer induces hypolipidemia and enhances hepatic catalase and carnitine acetyltransferase activities in rats and mice (1976) (125)
- Induction and origin of hepatocytes in rat pancreas (1984) (123)
- Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal beta-oxidation, PPAR alpha, and steatohepatitis. (2001) (122)
- Morphometric analysis of the ultrastructural changes in rat liver induced by the peroxisome proliferator SaH 42-348 (1976) (122)
- The hepatic effects of hypolipidemic drugs (clofibrate, nafenopin, tibric acid, and Wy-14,643) on hepatic peroxisomes and peroxisome-associated enzymes. (1978) (121)
- Expression of p53 protein in precursor lesions and adenocarcinoma of human pancreas. (1994) (121)
- Inhibitory effect of antioxidants ethoxyquin and 2(3)-tert-butyl-4-hydroxyanisole on hepatic tumorigenesis in rats fed ciprofibrate, a peroxisome proliferator. (1984) (120)
- Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids (2012) (118)
- Peroxisome proliferation and nongenotoxic carcinogenesis: Commentary on a symposium (1991) (117)
- Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis. (2001) (116)
- Detection of a nafenopin-binding protein in rat liver cytosol associated with the induction of peroxisome proliferation by hypolipidemic compounds. (1983) (115)
- Transcription Coactivator PBP, the Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein, Is Required for PPARα-regulated Gene Expression in Liver* (2004) (115)
- DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes. (1984) (114)
- Ductal metaplasia of human exocrine pancreas and its association with carcinoma. (1985) (113)
- Induction of hepatocytes in the pancreas of copper-depleted rats following copper repletion. (1986) (111)
- Almost total conversion of pancreas to liver in the adult rat: a reliable model to study transdifferentiation. (1988) (110)
- Molecular evolution of the urate oxidase-encoding gene in hominoid primates: nonsense mutations. (1991) (110)
- Development of hepatocellular carcinomas and increased peroxisomal fatty acid beta-oxidation in rats fed [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (Wy-14,643) in the semipurified diet. (1981) (109)
- Peroxisome Proliferator–induced Pleiotropic Responses: Pursuit of a Phenomenon a (1996) (109)
- An overview of peroxisome proliferator-induced hepatocarcinogenesis. (1991) (107)
- Analysis of peroxisome proliferator-induced preneoplastic and neoplastic lesions of rat liver for placental form of glutathione S-transferase and gamma-glutamyltranspeptidase. (1986) (106)
- Phthalate esters as peroxisome proliferator carcinogens. (1982) (106)
- Peroxisome proliterators and cancer: mechanisms and implications (1986) (104)
- Differential expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) and its coactivators steroid receptor coactivator-1 and PPAR-binding protein PBP in the brown fat, urinary bladder, colon, and breast of the mouse. (1998) (102)
- Absence of Spontaneous Peroxisome Proliferation in Enoyl-CoA Hydratase/l-3-Hydroxyacyl-CoA Dehydrogenase-deficient Mouse Liver (1999) (102)
- Tissue specificity and species differences in the distribution of urate oxidase in peroxisomes. (1988) (101)
- Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance. (2006) (100)
- Hepatocarcinogenicity of dehydroepiandrosterone in the rat. (1992) (98)
- Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP function (2001) (95)
- MICROBODIES IN EXPERIMENTALLY ALTERED CELLS II. The Relationship of Microbody Proliferation to Endocrine Glands (1969) (94)
- Malignant tumors in rats given lasiocarpine. (1972) (94)
- Properties of purified carnitine acyltransferases of mouse liver peroxisomes. (1984) (93)
- Differential induction and regulation of peroxisomal enzymes: predictive value of peroxisome proliferation in identifying certain nonmutagenic carcinogens. (1989) (93)
- Thyroid hormone (T3) inhibits ciprofibrate-induced transcription of genes encoding beta-oxidation enzymes: cross talk between peroxisome proliferator and T3 signaling pathways. (1995) (93)
- Comparison of hepatic peroxisome proliferative effect and its implication for hepatocarcinogenicity of phthalate esters, di(2-ethylhexyl) phthalate, and di(2-ethylhexyl) adipate with a hypolipidemic drug. (1986) (93)
- Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice (2012) (92)
- 32P-postlabeling analysis of peroxisome proliferator-DNA adduct formation in rat liver in vivo and hepatocytes in vitro. (1985) (89)
- The absence of gamma-glutamyl transpeptidase activity in putative preneoplastic lesions and in hepatocellular carcinomas induced in rats by the hypolipidemic peroxisome proliferator Wy-14,643. (1982) (87)
- Expression of Base Excision DNA Repair Genes Is a Sensitive Biomarker for in Vivo Detection of Chemical-induced Chronic Oxidative Stress (2004) (87)
- Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome. (2014) (86)
- Peroxisome proliferator-binding protein: identification and partial characterization of nafenopin-, clofibric acid-, and ciprofibrate-binding proteins from rat liver. (1987) (86)
- Peroxisome proliferation and nongenotoxic carcinogenesis: commentary on a symposium. (1991) (85)
- Peroxisome proliferators and peroxisome proliferator-activated receptor alpha: biotic and xenobiotic sensing. (2004) (85)
- Peroxisomes (microbodies) in cell pathology. (1984) (83)
- Isolation of the human peroxisomal acyl-CoA oxidase gene: organization, promoter analysis, and chromosomal localization. (1994) (82)
- Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells. (2001) (81)
- Peroxisomal beta-oxidation and steatohepatitis. (2001) (79)
- Less Extrahepatic Induction of Fatty Acid β-Oxidation Enzymes by PPARα (2000) (78)
- Pancreatic adenocarcinoma in inbred guinea pigs induced by n-methyl-N-nitrosourea. (1975) (78)
- Microbodies (peroxisomes) in the interstitial cells of rodent testes. (1972) (78)
- Mouse steroid receptor coactivator-1 is not essential for peroxisome proliferator-activated receptor alpha-regulated gene expression. (1999) (77)
- Phosphorylation of Transcriptional Coactivator Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein (PBP) (2002) (77)
- Coactivator PRIP, the Peroxisome Proliferator-activated Receptor-interacting Protein, Is a Modulator of Placental, Cardiac, Hepatic, and Embryonic Development* (2003) (76)
- Transcriptional Regulation of Cidea, Mitochondrial Cell Death-inducing DNA Fragmentation Factor α-Like Effector A, in Mouse Liver by Peroxisome Proliferator-activated Receptor α and γ* (2007) (76)
- PPARalpha in the pathogenesis of fatty liver disease. (2004) (76)
- EDGE: A Centralized Resource for the Comparison, Analysis, and Distribution of Toxicogenomic Information (2005) (74)
- POSSIBLE PROPERTIES OF MICROBODIES (PEROXISOMES) MICROBODY PROLIFERATION AND HYPOLIPIDEMIC DRUGS (1973) (74)
- Interaction of PIMT with Transcriptional Coactivators CBP, p300, and PBP Differential Role in Transcriptional Regulation* (2002) (73)
- Induction, immunochemical identity and immunofluorescence localization of an 80 000-molecular-weight peroxisome-proliferation-associated polypeptide (polypeptide PPA-80) and peroxisomal enoyl-CoA hydratase of mouse liver and renal cortex. (1981) (73)
- Immunocytochemical localization of catalase and heat-labile enoyl-CoA hydratase in the livers of normal and peroxisome proliferator-treated rats. (1982) (72)
- Enhancement by Wy-14,643, a hepatic peroxisome proliferator, of diethylnitrosamine-initiated hepatic tumorigenesis in the rat. (1978) (72)
- Effect of hypolipidemic peroxisome proliferators on unscheduled DNA synthesis in cultured hepatocytes and on mutagenesis in Salmonella. (1984) (72)
- PPARα in the pathogenesis of fatty liver disease (2004) (71)
- Transformation of mammalian cells by overexpressing H2O2-generating peroxisomal fatty acyl-CoA oxidase. (1995) (71)
- Evaluation of liver cell proliferation during ciprofibrate-induced hepatocarcinogenesis. (1989) (68)
- Transplantable pancreatic carcinoma of the rat (1977) (67)
- Identification of cytosolic peroxisome proliferator binding protein as a member of the heat shock protein HSP70 family. (1990) (65)
- Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen. (2003) (64)
- PAT5A: A Partial Agonist of Peroxisome Proliferator-Activated Receptor γ Is a Potent Antidiabetic Thiazolidinedione Yet Weakly Adipogenic (2003) (64)
- Cadmium-induced Leydig cell tumors of rat testis: morphologic and cytochemical study. (1973) (64)
- Characterization of pancreatic-type tissue in the liver of rat induced by polychlorinated biphenyls. (1986) (63)
- Sequential histologic study of rat liver during peroxisome proliferator [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]-acetic acid (Wy-14,643)-induced carcinogenesis. (1984) (63)
- Progressive endoplasmic reticulum stress contributes to hepatocarcinogenesis in fatty acyl-CoA oxidase 1-deficient mice. (2011) (62)
- Transcriptional Coactivator PRIP, the Peroxisome Proliferator-activated Receptor γ (PPARγ)-interacting Protein, Is Required for PPARγ-mediated Adipogenesis* (2003) (61)
- The peroxisome proliferation-associated polypeptide in rat liver. (1977) (61)
- Lack of Expression of Glutathione-S-transferase P, γ-Glutamyl Transpeptidase, and α-Fetoprotein Messenger RNAs in Liver Tumors Induced by Peroxisome Proliferators (1988) (61)
- Hepatocarcinogenesis of Peroxisome Proliferators a (1996) (61)
- Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity. (2005) (61)
- Hepatic transdifferentiation in the pancreas. (1995) (60)
- Human Peroxisome Proliferator-activated Receptor α (PPARα) Supports the Induction of Peroxisome Proliferation in PPARα-deficient Mouse Liver* (2001) (60)
- Initiation of the division cycle of rat hepatocytes following a single injection of thioacetamide. (1969) (60)
- Osteoclastoma‐like giant cell tumor of the liver (1980) (58)
- MICROBODIES (PEROXISOMES) IDENTIFICATION IN INTERSTITIAL CELLS OF THE TESTIS (1972) (57)
- Further evidence to suggest that microbodies do not exist as individual entities. (1973) (57)
- Biochemical characterization of two functional human liver acyl-CoA oxidase isoforms 1a and 1b encoded by a single gene. (2007) (56)
- Microbody proliferation in liver induced by nafenopin, a new hypolipidemic drug: comparison with CPIB. (1973) (56)
- Peroxisome proliferator-activated receptor-α activation and excess energy burning in hepatocarcinogenesis. (2014) (56)
- Microbodies in experimentally altered cells. 8. Continuities between microbodies and their possible biologic significance. (1971) (53)
- Transcriptional regulation of Cidea, mitochondrial cell death-inducing DNA fragmentation factor alpha-like effector A, in mouse liver by peroxisome proliferator-activated receptor alpha and gamma. (2007) (53)
- Response of chemically induced hepatocytelike cells in hamster pancreas to methyl clofenapate, a peroxisome proliferator (1982) (52)
- Transdifferentiation of ductular cells into hepatocytes in regenerating hamster pancreas. (1990) (52)
- PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid Oxidation. (2015) (52)
- Cooperative Formation of Higher Order Peroxisome Proliferator-activated Receptor and Retinoid X Receptor Complexes on the Peroxisome Proliferator Responsive Element of the Rat Hydratase-Dehydrogenase Gene (*) (1995) (51)
- Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice[S] (2010) (51)
- Protein Profiling of Mouse Livers with Peroxisome Proliferator-Activated Receptor α Activation (2004) (51)
- Human urate oxidase gene: cloning and partial sequence analysis reveal a stop codon within the fifth exon. (1990) (51)
- Association of peroxisome proliferator-activated receptor and Hsp72. (1994) (51)
- Transcription coactivator mediator subunit MED1 Is required for the development of fatty liver in the mouse (2011) (51)
- Stimulation of liver catalase synthesis in rats by ethyl-α-p-chlorophenoxyisobutyrate (1971) (51)
- Mitogenic effect in mouse liver induced by a hypolipidemic drug, nafenopin (1977) (49)
- Induction of rat liver DNA alterations by chronic administration of peroxisome proliferators as detected by 32P-postlabeling. (1991) (49)
- Hepatic oxidative stress activates the Gadd45b gene by way of degradation of the transcriptional repressor STAT3 (2014) (49)
- Less extrahepatic induction of fatty acid beta-oxidation enzymes by PPAR alpha. (2000) (49)
- Overexpression of Peroxisome Proliferator-activated Receptor-α (PPARα)-regulated Genes in Liver in the Absence of Peroxisome Proliferation in Mice Deficient in both l- and d-Forms of Enoyl-CoA Hydratase/Dehydrogenase Enzymes of Peroxisomal β-Oxidation System* (2003) (49)
- Upregulation of calpastatin in regenerating and developing rat liver: Role in resistance against hepatotoxicity (2006) (48)
- Critical Role for Transcription Coactivator Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein/TRAP220 in Liver Regeneration and PPARα Ligand-induced Liver Tumor Development* (2007) (48)
- Conditional ablation of mediator subunit MED1 (MED1/PPARBP) gene in mouse liver attenuates glucocorticoid receptor agonist dexamethasone-induced hepatic steatosis. (2009) (47)
- Irreversible inhibition of hepatic glutathione S-transferase by ciprofibrate, a peroxisome proliferator. (1984) (47)
- MICROBODIES IN LEYDIG CELL TUMORS OF RAT TESTIS (1972) (47)
- Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα (2010) (46)
- Increase in hepatic carnitine acetyltransferase activity associated with peroxisomal (microbody) proliferation induced by the hypolipidemic drugs clofibrate, nafenopin, and methyl clofenapate. (1974) (45)
- Malignant neoplasms in rats fed lasiocarpine. (1978) (45)
- Stem cell potential of ductular and periductular cells in the adult rat pancreas. (1990) (45)
- Neoplastic conversion of human urothelial cells in vitro by overexpression of H2O2-generating peroxisomal fatty acyl CoA oxidase. (1999) (44)
- The relationship of nucleolar segregation to ribonucleic acid synthesis following the administration of selected hepatocarcinogens. (1968) (44)
- Stimulation of catalase synthesis and increase of carnitine acetyltransferase activity in the liver of intact female rats fed clofibrate. (1979) (43)
- The Neuronal Migration Defect in Mice with Zellweger Syndrome (Pex5 Knockout) is not Caused by the Inactivity of Peroxisomal β‐Oxidation (2002) (43)
- Beta-oxidation in hepatocyte cultures from mice with peroxisomal gene knockouts. (2007) (42)
- Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected]. (2010) (42)
- Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1 (2010) (42)
- Absence of gamma-glutamyl transpeptidase activity in neoplastic lesions induced in the liver of male F-344 rats by di-(2-ethylhexyl)phthalate, a peroxisome proliferator. (1987) (42)
- PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex. (2006) (42)
- Studies of pancreatic carcinogenesis in different animal models. (1984) (42)
- Baculovirus expression of the Ah receptor and Ah receptor nuclear translocater. Evidence for additional dioxin responsive element-binding species and factors required for signaling. (1994) (41)
- The Med1 Subunit of Transcriptional Mediator Plays a Central Role in Regulating CCAAT/Enhancer-binding Protein-β-driven Transcription in Response to Interferon-γ* (2008) (41)
- Transformation of epithelial cells stably transfected with H2O2-generating peroxisomal urate oxidase. (1996) (41)
- Invasive tumors induced in rats with actinomycin D. (1970) (41)
- Hepatic microbody proliferation and catalase synthesis induced by methyl clofenapate, a hypolipidemic analog of CPIB. (1974) (41)
- MICROBODIES IN EXPERIMENTALLY ALTERED CELLS (1969) (40)
- The peroxisomal enzyme L-PBE is required to prevent the dietary toxicity of medium-chain fatty acids. (2013) (40)
- Hepatic regeneration in peroxisome proliferator-activated receptor alpha-null mice after partial hepatectomy. (2002) (40)
- Induction of fatty acid beta-oxidation and peroxisome proliferation in the liver of rhesus monkeys by DL-040, a new hypolipidemic agent. (1985) (39)
- Dehydroepiandrosterone-induced peroxisome proliferation in the rat liver. (1992) (39)
- Nuclear Receptor Coactivator 6 Mediates the Synergistic Activation of Human Cytochrome P-450 2C9 by the Constitutive Androstane Receptor and Hepatic Nuclear Factor-4α (2008) (39)
- MICROBODIES IN EXPERIMENTALLY ALTERED CELLS : VII. CPIB-induced Hepatic Microbody Proliferation in the Absence of Significant Catalase Synthesis (1970) (39)
- Peroxisomes: Biology and Role in Toxicology and Disease. Proceedings from an international symposium. Aspen, Colorado, June 28-July 2, 1995. (1996) (39)
- Coactivator MED1 Ablation in Keratinocytes Results in Hair Cycling Defects and Epidermal Alternations (2011) (38)
- Specific changes in the protein composition of rat liver in response to the peroxisome proliferators ciprofibrate, Wy-14,643 and di-(2-ethylhexyl)phthalate. (1985) (38)
- Induction of Nuclear Translocation of Constitutive Androstane Receptor by Peroxisome Proliferator-activated Receptor α Synthetic Ligands in Mouse Liver* (2007) (38)
- Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination (2016) (37)
- MICROBODIES IN EXPERIMENTALLY ALTERED CELLS (1970) (37)
- Serum triglyceride and cholesterol contents in male rats receiving diets containing plasticizers and analogues of the ester 2-ethylhexanol. (1982) (37)
- Role of apoptosis in copper deficiency-induced pancreatic involution in the rat. (1993) (36)
- Pancreatic hepatocytes. An in vivo model for cell lineage in pancreas of adult rat. (1991) (36)
- Transdifferentiated hepatocytes in rat pancreas. (1986) (35)
- Histogenesis of pseudo-ductular changes induced in the pancreas of guinea pigs treated with N-methyl-N-nitrosourea. (1980) (35)
- Lack of covalent binding of peroxisome proliferators nafenopin and Wy-14 643 to DNA in vivo and in vitro. (1985) (34)
- Peroxisome proliferator–activated receptor‐α−/− mice show enhanced hepatocyte proliferation in response to the hepatomitogen 1,4‐bis[2‐(3,5‐dichloropyridyloxy)] benzene, a ligand of constitutive androstane receptor (2001) (34)
- Partial purification and immunoreactivity of an 80 000-molecular-weight polypeptide associated with peroxisome proliferation in rat liver. (1980) (34)
- Hepatocyte growth factor/scatter factor-Met signaling induces proliferation, migration, and morphogenesis of pancreatic oval cells. (1996) (34)
- Immunocytochemical localization of fatty acid metabolizing heat-stable and heat-labile enoyl-coenzyme A (CoA) hydratases in liver and renal cortex. (1983) (34)
- Identification of promethin and PGLP as two novel up-regulated genes in PPARgamma1-induced adipogenic mouse liver. (2004) (34)
- Carcinogenicity of peroxisome proliferators: evaluation and mechanisms. (1990) (33)
- Loss of peroxisomal enzyme expression in preneoplastic and neoplastic lesions induced by peroxisome proliferators in rat livers. (1992) (33)
- Reversible alteration of hepatic messenger RNA species for peroxisomal and non-peroxisomal proteins induced by the hypolipidaemic drug Wy-14,643. (1983) (33)
- Rat urate oxidase produced by recombinant baculovirus expression: formation of peroxisome crystalloid core-like structures. (1992) (32)
- Uric acid degrading enzymes, urate oxidase and allantoinase, are associated with different subcellular organelles in frog liver and kidney. (1994) (32)
- Inhibition by Lasiocarpine of RNA Synthesis, RNA Polymerase and Induction of Tryptophan Pyrrolase Activity (1968) (32)
- Induction of Hamster Hepatic Peroxisomal β-oxidation and Peroxisome Proliferation-associated 80000 mol. wt. Polypeptide by Hypolipidemic Drugs (1982) (32)
- Induction of peroxisome proliferation and hepatic tumours in C57BL/6N mice by ciprofibrate, a hypolipidaemic compound. (1988) (32)
- Hepatic peroxisome proliferation: induction by BR-931, a hypolipidemic analog of WY-14,643. (1978) (32)
- Cloning and Identification of Rat Deoxyuridine Triphosphatase as an Inhibitor of Peroxisome Proliferator-activated Receptor α* (1996) (32)
- Microbodies in experimentally altered cells. V. Histochemical and cytochemical studies on the livers of rats and acatalasemic (Csb) mice treated with CPIB. (1969) (31)
- The Inflammatory Response in Acyl-CoA Oxidase 1 Deficiency (Pseudoneonatal Adrenoleukodystrophy) (2012) (30)
- Hepatic Lipid Metabolism (2011) (30)
- Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver. (2001) (29)
- Mediator 1 Is Atherosclerosis Protective by Regulating Macrophage Polarization (2017) (29)
- Immunocytochemical localization of urate oxidase, fatty acyl-CoA oxidase, and catalase in bovine kidney peroxisomes. (1988) (29)
- Expression of transcription factors and stem cell factor precedes hepatocyte differentiation in rat pancreas. (1996) (29)
- Transcriptional coactivator PRIP, the peroxisome proliferator-activated receptor gamma (PPARgamma)-interacting protein, is required for PPARgamma-mediated adipogenesis. (2003) (29)
- Inhibition of spontaneous testicular Leydig cell tumor development in F-344 rats by dehydroepiandrosterone. (1992) (28)
- Response of hepatocytes transplanted into syngeneic hosts and heterotransplanted into athymic nude mice to peroxisome proliferators. (1984) (28)
- Localization of the human urate oxidase gene (UOX) to 1p22. (1992) (28)
- Susceptibility of an ibred strain of guinea pigs to the induction of pancreatic adenocarcinoma by N-methyl-N-nitrosourea. (1974) (28)
- Pancreatic necrosis and regeneration induced by 4-hydroxyaminoquinoline-1-oxide in the guinea pig. (1975) (28)
- Overexpression and Characterization of the Human Peroxisomal Acyl-CoA Oxidase in Insect Cells (*) (1995) (28)
- Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse (2009) (27)
- Peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP) but not PPAR-interacting protein (PRIP) is required for nuclear translocation of constitutive androstane receptor in mouse liver. (2006) (27)
- Induction of Hepatic Peroxisome Proliferation by Xenobiotics (1987) (27)
- Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene (2009) (27)
- Pathology of the liver in Reye's syndrome. (1975) (27)
- Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. (2012) (27)
- Peroxisome proliferator-activated receptor alpha-responsive genes induced in the newborn but not prenatal liver of peroxisomal fatty acyl-CoA oxidase null mice. (2001) (27)
- Peroxisome proliferator-induced hepatocarcinogenesis: histochemical analysis of ciprofibrate-induced preneoplastic and neoplastic lesions for gamma-glutamyl transpeptidase activity. (1986) (26)
- Med1 subunit of the mediator complex in nuclear receptor-regulated energy metabolism, liver regeneration, and hepatocarcinogenesis. (2014) (26)
- Beckwith-Wiedemann syndrome. Wilms' tumor, cardiac hamartoma, persistent visceromegaly, and glomeruloneogenesis in a 2-year-old boy. (1972) (26)
- Protein profiling of mouse livers with peroxisome proliferator-activated receptor alpha activation. (2004) (26)
- Nuclear receptors and transcription factors in the development of fatty liver disease. (2012) (26)
- Immunocytochemical localization of liver-specific proteins in pancreatic hepatocytes of rat. (1988) (26)
- Noninhibitory effect of antioxidants ethoxyquin, 2(3)-tert-butyl-4-hydroxyanisole and 3,5-di-tert-butyl-4-hydroxytoluene on hepatic peroxisome proliferation and peroxisomal fatty acid beta-oxidation induced by a hypolipidemic agent in rats. (1983) (25)
- Differentiation of pancreatic acinar carcinoma cells cultured on rat testicular seminiferous tubular basement membranes. (1984) (25)
- Comparison of the Peroxisome Proliferator-Induced Pleiotropic Response in the Liver of Nine Strains of Mice (1989) (25)
- Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice (2016) (25)
- Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system. (2003) (25)
- Pigment epithelium-derived factor is an angiogenesis and lipid regulator that activates peroxisome proliferator-activated receptor alpha. (2008) (24)
- Elevated hepatocyte levels of the Forkhead box A2 (HNF‐3β) transcription factor cause postnatal steatosis and mitochondrial damage (2003) (24)
- Differentiation and DNA synthesis in pancreatic acinar carcinoma of rat. (1980) (24)
- Peroxisome proliferator-induced hepatocarcinogenesis: levels of activating and detoxifying enzymes in hepatocellular carcinomas induced by ciprofibrate. (1987) (24)
- Polyribosome disaggregation in rat liver following administration of tannic acid. (1970) (24)
- Tumorigenic conversion of a non‐tumorigenic rat urothelial cell line by overexpression of H2O2‐generating peroxisomal fatty acyl‐CoA oxidase (1997) (23)
- Dehydroepiandrosterone-Induced Peroxisome Proliferation in the Rat: Evaluation of Sex Differences (1994) (23)
- Hepatic effects of some [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (WY-14,643) analogs in the mouse. (1977) (23)
- Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4 (2015) (23)
- Targeted Disruption of the Peroxisomal Fatty Acyl‐CoA Oxidase Gene: Generation of a Mouse Model of Pseudoneonatal Adrenoleukodystrophy a (1996) (22)
- Peroxisome proliferator-activated receptor-α signaling in hepatocarcinogenesis. (2013) (22)
- Microbody (Peroxisome) proliferation in mouse kidney induced by methyl clofenapate (1975) (22)
- Comparison of secretory protein and membrane composition of secretory granules isolated from normal and neoplastic pancreatic acinar cells of rats. (1983) (22)
- Microbodies in experimentally altered cells. IX. The fate of microbodies. (1972) (22)
- Coexpression of glutamine synthetase and carbamoylphosphate synthase I genes in pancreatic hepatocytes of rat. (1990) (22)
- Induction of malignant vascular tumors of the liver in guinea pigs treated with 2,2'-dihydroxy-di-n-propylnitrosamine. (1977) (21)
- Transplantable acinar cell carcinoma of the rat pancreas. (1979) (21)
- The Med1 Subunit of the Mediator Complex Induces Liver Cell Proliferation and Is Phosphorylated by AMP Kinase* (2013) (21)
- Estradiol receptor assays in normal and neoplastic tissues. A possible diagnostic acid for tumor differentiation. (1979) (21)
- Purification, properties, and immunocytochemical localization of human liver peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. (1987) (21)
- Induction of peroxisomal enzymes in livers of neonatal rats exposed to lactating mothers treated with hypolipidaemic drugs. Role of drug metabolite transfer in milk. (1983) (20)
- Xenobiotic-induced peroxisome proliferation: role of tissue specificity and species differences in response in the evaluation of the implications for human health. (1987) (20)
- Rapid development of hyperplastic nodules and cirrhosis in the liver of rats treated concurrently with thioacetamide and the pyrrolizidine alkaloid lasiocarpine (1976) (20)
- Alteration of Skin Wound Healing in Keratinocyte-Specific Mediator Complex Subunit 1 Null Mice (2014) (20)
- Pancreatic hepatocytes (1991) (20)
- Peroxisome proliferator-induced alterations in the expression and modification of rat hepatocyte plasma membrane proteins. (1990) (20)
- The relevance of peroxisome proliferation and cell proliferation in peroxisome proliferator-induced hepatocarcinogenesis. (1989) (20)
- An in vitro demonstration of peroxisome proliferation and increase in peroxisomal β‐oxidation system mRNAs in cultured rat hepatocytes treated with ciprofibrate (1989) (20)
- Increased expression of sulfated glycoprotein-2 and DNA fragmentation in the pancreas of copper-deficient rats. (1994) (19)
- An upstream region of the enoyl-coenzyme A hydratase/3-hydroxyacyl-coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice. (1994) (19)
- Phenotypic Properties of Liver Tumors Induced by Dehydroepiandrosterone in F‐344 Rats (1992) (19)
- Induction of peroxisome proliferation in hepatocytes transplanted into the anterior chamber of the eye. A model system for the evaluation of xenobiotic-induced effects. (1986) (19)
- Hepatic megalocytosis in chronic lasiocarpine poisoning. Some functional studies. (1971) (18)
- Roles of MED1 in quiescence of hair follicle stem cells and maintenance of normal hair cycling. (2013) (18)
- Role of AMACR (α-methylacyl-CoA racemase) and MFE-1 (peroxisomal multifunctional enzyme-1) in bile acid synthesis in mice. (2014) (18)
- Transcriptional and Translational Modulation of myo-Inositol Oxygenase (Miox) by Fatty Acids (2015) (18)
- Immunohistochemical localization of pancreatic exocrine enzymes in normal and neoplastic pancreatic acinar epithelium of rat. (1981) (17)
- Effect of peroxisome proliferators on intrachromosomal and interchromosomal recombination in yeast. (1990) (17)
- Theme Lipid Metabolism and Liver Inflammation . II . Fatty liver disease and fatty acid oxidation (2006) (17)
- The nucleotide sequence of a full length cDNA clone encoding rat liver urate oxidase. (1989) (17)
- 1-methyl-4piperidyl-bis (P-chlorophenoxy) acetate: a new hypolipidemic peroxisome proliferator. (1975) (17)
- Microbody (Peroxisome) matrix: Transformation into tubular structures (1973) (16)
- Alterations of pancreatic hepatocytes in rats exposed to carcinogens. (1991) (16)
- Some Effects of Chemical Carcinogens on Cell Organelles (1975) (16)
- Ciprofibrate represses α2u-globulin expression in liver and inhibits d-limonene nephrotoxicity (1996) (16)
- Formation of ductular structures in vitro by rat pancreatic epithelial oval cells. (1993) (16)
- Profiling of acyl-CoA oxidase-deficient and peroxisome proliferator Wy14,643-treated mouse liver protein by surface-enhanced laser desorption/ionization ProteinChip Biology System. (2002) (16)
- Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase. (1998) (16)
- ERK2-Mediated Phosphorylation of Transcriptional Coactivator Binding Protein PIMT/NCoA6IP at Ser298 Augments Hepatic Gluconeogenesis (2013) (16)
- Polyribosome disaggregation in rat liver by lasiocarpine. (1969) (15)
- Differentiation and cell proliferation patterns in rat exocrine pancreas: role of type I and type II injury. (1990) (15)
- Concanavalin A agglutinability and surface microvilli of dissociated normal and neoplastic pancreatic acinar cells of the rat. (1979) (15)
- Peroxisome development in the regenerating pars recta (P3 segment) of proximal tubules of the rat kidney. (1976) (15)
- Increased peroxisomal activity in the liver of vitamin E deficient rats (1981) (15)
- Deletion of a Malaria Invasion Gene Reduces Death and Anemia, in Model Hosts (2011) (15)
- Functional expression and peroxisomal targeting of rat urate oxidase in monkey kidney cells. (1995) (15)
- Pancreatic acinar cell regeneration following copper deficiency-induced pancreatic necrosis (1986) (15)
- PANCREATIC BIOTINIDASE ACTIVITY: THE POTENTIAL FOR INTESTINAL PROCESSING OF DIETARY PROTEIN-BOUND BIOTIN (1984) (15)
- Nuclear receptor transcriptional coactivators in development and metabolism (2006) (14)
- Carbamylcholine stimulation of protein secretion in pancreatic acinar carcinoma of rat. (1982) (14)
- Transcription coactivator PRIP, the peroxisome proliferator-activated receptor (PPAR)-interacting protein, is redundant for the function of nuclear receptors PParalpha and CAR, the constitutive androstane receptor, in mouse liver. (2006) (14)
- Neoplasia and chronic disease associated with the prolonged administration of dehydroheliotridine to rats. (1983) (14)
- Expression and compartmentalization of integral plasma membrane proteins by hepatocytes and their progenitors in the rat pancreas. (1991) (14)
- Interstitial Cell Tumor, Testis, Rat (1987) (14)
- PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex (2010) (14)
- Immunocytochemical Study of the Ultrastructure of Peroxisomes and the Effects of Peroxisome Proliferators a (1996) (14)
- Comparative effects of dehydroepiandrosterone and related steroids on peroxisome proliferation in rat liver. (1993) (14)
- Increased peroxisomal enzyme mRNA levels in adult rat hepatocytes cultured in a chemically defined medium and treated with nafenopin. (1988) (13)
- Duct-like morphogenesis of Longnecker pancreatic acinar carcinoma cells maintained in vitro on seminiferous tubular basement membranes. (1986) (13)
- In vivo distribution of a carcinogenic hepatic peroxisome proliferator: whole-body autoradiography of [14C]ciprofibrate in the mouse. (1989) (13)
- Di-(2-ethylhexyl)phthalate: an industrial plasticizer induces hypolipidemia and enhances hepatic catalase and carnitine acetyltransferase activities in rat and mice. (1976) (13)
- Brief Communication: Laslocarplne-Induced, Transplantable Squamous Cell Carcinoma of Rat Skin (1974) (12)
- Hepatic Catalase Is Not Essential for the Hypolipidemic Action of Peroxisome Proliferators 1 (1977) (12)
- The ultrastructural effects of aflatoxin B1 in the rat pancreas (1975) (12)
- Mutagenicity of the pyrrolizidine (Senecio) alkaloid, lasiocarpine in the Salmonella/microsome test (1978) (12)
- Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPARγ and Identification of TUSC5 Coding Variants in Lean and Obese Humans (2010) (12)
- Hepatic Peroxisome Proliferation: An Overview (1988) (12)
- Functional expression of rat peroxisomal acyl-CoA oxidase in Spodoptera frugiperda cells. (1994) (12)
- Expression of peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase enzyme and its mRNA in peroxisome proliferator-induced liver tumors. (1994) (12)
- Secretion granules of transplantable pancreatic acinar carcinoma of rat. (1980) (12)
- Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα (2010) (12)
- Carcinogenicity of 2,2'-dihydroxy-di-n-propylnitrosamine in the tree shrew (Tupaia glis): light and electron microscopic features of pulmonary adenomas. (1980) (12)
- TRANSCRIPTIONAL AND TRANSLATIONAL MODULATION OF MYO-INOSITOL OXYGENASE (MIOX) BY FATTY ACIDS: IMPLICATIONS IN RENAL TUBULAR INJURY INDUCED IN OBESITY AND DIABETES (2015) (12)
- Natural segregation of nucleolar components of liver cells in newts. (1972) (12)
- 662 – STRUCTURE-ACTIVITY RELATIONSHIPS OF CLOFIBRATE-LIKE COMPOUNDS ON LIPID METABOLISM (1977) (12)
- Peroxisome-associated enzymes and serum lipids in tumour-bearing rats treated with peroxisome-proliferating agents. (1984) (12)
- Induction by ciprofibrate of hepatic peroxisome proliferation in rats, pigeons, chickens, cats and rhesus monkeys (1982) (11)
- Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members. (2007) (11)
- Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin. (1995) (11)
- Testicular feminization of the mouse: paucity of peroxisomes in Leydig cell of the testis. (1981) (11)
- Phenotypic Properties of Preneoplastic and Neoplastic Hepatic Lesions Induced by Peroxisome Proliferators in Rats (1987) (10)
- Antidiabetic Activity of Ethanolic Extract of Hydnocarpus Wightiana Blume Using Stz Induced Diabetes in Sd Rats (2013) (10)
- Are acinar cells involved in the pathogenesis of ductal adenocarcinoma of the pancreas? (1991) (10)
- Separation and characterization of neoplastic cell subpopulations of a transplantable rat pancreatic acinar carcinoma. (1982) (10)
- Pancreatic regeneration caused by ethionine in the guinea pig. (1974) (10)
- gamma-Glutamyltranspeptidase-negative phenotypic property of preneoplastic and neoplastic liver lesions induced by ciprofibrate does not change following 2-acetylaminofluorene administration. (1989) (10)
- Excessive lipofuscin accumulation in the thyroid gland in mucoviscidosis. (1973) (10)
- Lack of expression of glutathione-S-transferase P, gamma-glutamyl transpeptidase, and alpha-fetoprotein messenger RNAs in liver tumors induced by peroxisome proliferators. (1988) (10)
- Mutational Analysis of the Putative Copper‐binding Site of Rat Urate Oxidase a (1996) (10)
- Proliferation of microbodies and synthesis of catalase in rat liver. Induction in tumor-bearing host by CPIB. (1971) (10)
- Androgen regulated expression of the alpha 2u-globulin gene in pancreatic hepatocytes of rat (1990) (9)
- Isolation and ultrastructure of nucleoli altered in vivo. (1968) (9)
- Transplantable pancreatic acinar carcinoma (1981) (9)
- PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism (2018) (9)
- Induction and differentiation of exocrine pancreatic tumors in the rat. (1985) (9)
- Intracellular transport and storage of secretory proteins in relation to cytodifferentiation in neoplastic pancreatic acinar cells (1983) (9)
- IMMUNOCYTOCHEMICAL LOCALIZATION OF CATALASE, HEAT‐LABILE ENOYL‐CoA HYDRATASE, AND POLYPEPTIDE PPA‐80 IN RAT LIVER * (1982) (8)
- Laslocarpine-induced, transplantable squamous cell carcinoma of rat skin. (1974) (8)
- Induction of hepatic ornithine decarboxylase by hypolipidemic drugs with hepatic peroxisome proliferative activity. (1981) (8)
- 1 Adipocyte-specific Gene Expression and Adipogenic Steatosis in the Mouse Liver due to PPAR γ 1 Overexpression * (2002) (8)
- Tannic acid-induced nucleolar changes in hepatocytes transplanted into syngeneic or xenogeneic host and in hepatocytes maintained in primary culture. (1987) (8)
- Effect of lasiocarpine on aflatoxin B 1 carcinogenicity in rat liver. (1972) (8)
- Progress in pancreatic cancer: implications of phenotypic and molecular plasticity. (1995) (7)
- Degradation kinetics of liver catalase in rats treated with ethyl-alpha-p-chlorophenoxyisobutyrate. (1971) (7)
- The effect of cycloheximide on ribonucleic acid and protein synthesis in rat liver. (1969) (7)
- Pathology of tumors developed in guinea pigs given intraperitoneal injections of N-methyl-N-nitrosourea. (1977) (7)
- Demonstration of kallikrein in a rat pancreatic acinar cell carcinoma. (1985) (7)
- Concanavalin A binding and cytodifferentiation in pancreatic acinar carcinoma of rat. (1982) (7)
- Med1 regulates meiotic progression during spermatogenesis in mice. (2015) (7)
- Rat urate oxidase: cloning and structural analysis of the gene and 5'-flanking region. (1991) (7)
- The effect of microvesicular fatty change on liver regeneration after partial hepatectomy. (2000) (6)
- Ciprofibrate represses alpha 2u-globulin expression in liver and inhibits d-limonene nephrotoxicity. (1996) (6)
- Immunocytochemical localization of exocrine enzymes in rat pancreatic acinar carcinoma. (1984) (6)
- Multinucleate giant cells in livers of marmosets given aflatoxin B1. (1971) (6)
- Experimental Carcinogenesis of Exocrine Pancreas: Animal Models, Neoplasms, and Current Understanding of Pathogenesis (1985) (6)
- Effect of Calorie Restriction on the Fate of Hyperplastic Liver Nodules Induced by Concurrent Administration of Lasiocarpine and Thioacetamide (1983) (6)
- Correction: Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice (2016) (5)
- Increased resistance of peroxisome proliferator-induced hepatic lesions to iron overload in rats. (1986) (5)
- Plasma membrane retrieval in neoplastic pancreatic acinar cells. (1983) (5)
- www.cognizantcommunication.com Identification of Novel Peroxisome Proliferator-Activated Receptor α (PPAR α ) Target Genes in Mouse Liver Using cDNA Microarray (2001) (5)
- Computerized tomography and ultrasound in the diagnosis of cerebro-hepato-renal syndrome of Zellweger (1987) (5)
- Abstract 492: Hepatic oxidative stress activates the Gadd45b gene via degradation of the transcriptional repressor STAT3 (2014) (5)
- Alteration of a membrane associated marker in transplantable rat pancreatic acinar cell carcinoma. (1984) (5)
- Peroxisome Proliferation-Related Oxidative Stress and Hepato-Carcinogenesis (1987) (5)
- Purification and characterization of α-amylase from rat pancreatic acinar carcinoma: comparison with pancreatic α-amylase (1987) (5)
- Replicative culture in vitro of pancreatic epithelial oval cells derived from rats after copper deficiency-induced acinar cell depletion (1991) (5)
- Myosin from pancreatic acinar carcinoma cells. Isolation, characterization and demonstration of heavy- and light-chain phosphorylation. (1987) (5)
- Pancreatic stem cells (2007) (5)
- Mice lacking transcription cofactor PRIC285 reveal attenuation of liver regeneration but are viable and develop normally (2009) (5)
- Incorporation of [35S]sulfate in normal and neoplastic rat pancreatic acinar cells in relationship to cytodifferentiation. (1984) (4)
- Trimethylguanosine synthase 1 is a novel regulator of pancreatic beta-cell mass and function (2022) (4)
- Stimulation of liver catalase synthesis in rats by ethyl-alpha-p-chlorophenoxyisobutyrate. (1971) (4)
- Absence of increased carnitine acetyltransferase activity in the liver with proliferation of smooth endoplasmic reticulum. (1977) (4)
- Peroxisome proliferator-activated receptor alpha-dependent induction of cell surface antigen Ly-6D gene in the mouse liver. (2001) (4)
- Mouse Cardiac Pde1C Is a Direct Transcriptional Target of Pparα (2018) (4)
- Cloning and identification of rat deoxyuridine triphosphatase as an inhibitor of peroxisome proliferator-activated receptor alpha. (1996) (4)
- Hepatic ultrastructure and adaptation. (1987) (4)
- Erratum: Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene (Journal of Biological Chemistry (1996) 271 (2147-2155)) (1998) (4)
- Isolation of PBP165 as a cofactor of peroxisome proliferator activated receptor(PPAR)gamma (1997) (4)
- Identification of cytosolic peroxisome proliferator binding protein as a member of the heat shock protein HSP 70 family ( peroxisomes / drug-binding protein ) (4)
- MICROBODIES IN EXPERIMENTALLY ALTERED CELLS (1969) (4)
- CHAPTER 19 – Some Effects of Carcinogens on the Structure and Activity of Liver Cells (1970) (4)
- Metaplastic Transformation of Pancreatic Cells to Hepatocytes (1989) (3)
- Modulation of the phenotypic expression of rat hepatocyte nodules hn by a hypolipidemic agent ciprofibrate cf (1987) (3)
- Absence of gamma-glutamyltranspeptidase activity in lung metastasis in rats with hepatocellular carcinomas induced by ciprofibrate, a peroxisome proliferator. (1987) (3)
- Estradiol receptors in the transplantable pancreatic carcinoma of the rat (1978) (3)
- A comparative study of the effects of clofibrate, ciprofibrate, WY-14,643, and di-(2-ethylhexyl)-phthalate on liver protein expression in mice. (1991) (3)
- themes Nonalcoholic Steatosis and Steatohepatitis III. Peroxisomal b -oxidation, PPAR a , and steatohepatitis (2001) (3)
- Amphibian Catalase: Cloning, Tissue Distribution, and Peroxisomal Localization (1996) (3)
- Purification and characterization of alpha-amylase from rat pancreatic acinar carcinoma. Comparison with pancreatic alpha-amylase. (1987) (3)
- Foreword (1996) (3)
- Cloning and expression of the mouse deoxyuridine triphosphate nucleotidohydrolase gene: differs from the rat enzyme in that it lacks nuclear receptor interacting LXXLL motif. (1999) (2)
- Induction of hepatic peroxisomes, peroxisome associated enzymes and hypolipidemia in rats treated with 2 ethyl hexanoic acid and 2 ethyl hexanol (1976) (2)
- Localization of carbamylphosphate synthetase (ammonia) (CPS) in pancreatic hepatocytes of rat (1985) (2)
- Transcription coactivator PBP/MED1 regulates hepatocyte size and hepatocellular regeneration in the mouse (2006) (2)
- Morphometric analysis of ultrastructural changes in rat liver induced by peroxisome proliferators (1975) (2)
- Tissue specificity in the induction of peroxisome proliferation-associated polypeptide (PPA-80) and peroxisomal β-oxidation in rats by ciprofibrate (1985) (2)
- 4 Hydroxyaminoquinoline 1 oxide induced pancreatic necrosis and regeneration in the guinea pig: ultrastructural and autoradiographic studies (1975) (2)
- Rous-Whipple Award Lecture Peroxisome Proliferators and Peroxisome Proliferator-Activated Receptor (cid:1) Biotic and Xenobiotic Sensing (2004) (2)
- Hepatocarcinogenicity of wy-14,643, a hypolipidemic peroxisome proliferator. Abstr. (1978) (2)
- Comparative effects of hypolipidemic drugs on hepatic peroxisomal enzymes (1976) (2)
- Erratum: Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα (Laboratory Investigation (2010) 90 (696-708) DOI: 10.1038/labinvest.2010.46) (2010) (2)
- Production in vivo of falloff monosomes in mouse liver by sparsomycin. (1977) (2)
- Testicular Feminization, Testes, and Testicular Tumors, Rat, Mouse (1987) (2)
- Bipotential stem cells in the rat pancreas (1994) (2)
- 32P-postlabeling (32P) analysis of DNA adduct formation with carcinogenic peroxisome proliferators (1985) (1)
- Binding of labeled N-methyl N-nitrosourea to macromolecules of squamous and glandular stomach of rats. (1976) (1)
- Acyl‐CoA Oxidase, Peroxisomal (2002) (1)
- Ethyl-α-p-chlorophenoxyisobutyrate induced hepatic microbody proliferation in rat liver and ubiquinone concentration (1971) (1)
- Peroxisome proliferation and hepatocarcinogenesis. (1987) (1)
- Some Effects of Carcinogens on Cell Organelles (1982) (1)
- Investigational strategies for detection and intervention in early-stage pancreatic cancer (1994) (1)
- Increased lipid peroxidation in the rat liver following induction of peroxisome proliferation (1985) (1)
- Chronic Pancreatic Toxicity — Role of Stem Cells in the Conversion of Pancreas to Liver (2005) (1)
- Sub cellular changes in exocrine pancreas of the guinea pig induced by azaserine (1976) (1)
- Secretion Granules ofTransplantable Pancreatic Acinar Carcinoma ofRat (1980) (1)
- Isolation of Granule-Rich and Granule-Deficient Cell Populations from Acinar Carcinoma of Rat Pancreas (1987) (1)
- Regeneration of the Guinea Pig Parotid Gland after 4-hydroxyaminoquinoline-1-oxide-lnduced Necrosis (1976) (1)
- Peroxisome Proliferation: A Biological Marker for Toxicological Evaluation (1992) (1)
- Testicular feminization of the mouse: reduction of peroxisome population in Leydig cells of the testis (1975) (1)
- HISTOCHEMISTRY OF PEROXISOMES : OVERVIEW (1995) (1)
- Transcriptional regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators (catalase/fatty acid .-oxidation/dofibrate/ciprofibrate/bis(2-ethylhexyl) phthalate) (2016) (0)
- In MemoriamIn Memoriam (1999) (0)
- Aflatoxin B1 induced liver tumors in Tupaia glis (tree shrews), a nonhuman primate (1975) (0)
- Damage by Peroxisome Proliferators of the Molecular Source of Radicals Responsible for DNA Chemical-induced Chronic Oxidative Stress : Identification Detection of in Vivo Sensitive Biomarker for Expression of Base Excision DNA Repair Genes Is a (2004) (0)
- Response of Chemically Induced Hepatocytelike Cells Hamster Pancreas to Methyl Clofenapate, A Peroxisome Proliferator in M. SAMBASIVA RAO, M. KUMUDAVALLI REDDY, JANARDAN K. REDDY.. and DANTE G. SCARPELLI (2003) (0)
- Transcription coactivator PBP/MED1 deficiency prevents dexamethasone‐induced fatty liver (2006) (0)
- Peroxisomal enzyme changes in mouse kidney induced by methyl-2-[4-(p-chlorophenyl)-phenoxy]-2-methylpropionate (1980) (0)
- The effect of cyclopropenoid fatty acids on binding of aflatoxin B1 to nuclear DNA, RNA and protein of rat hepatocytes (1975) (0)
- Expression of protein, P24 in two transplantable pancreatic cancer carcinomas (PACA) of rat (1985) (0)
- Isolation and sequence determination of a cDNA clone for rat peroxisomal urate oxidase : Liver-specific expression in the rat ( tissue specificity / peroxisome proliferators / primer extension ) (0)
- Incorporation of [ 35 S ] Sulfate in Normal and Neoplastia Rat Pancreatic Acinar Cells in Relationship to Cytodifferentiation 1 (2006) (0)
- Transcription coactivator PRIP is not essential for the function of nuclear receptors CAR and PPARα in liver (2006) (0)
- Nafenopin: A hypolipidemic hepatic peroxisome proliferator that induces hepatocellular carcinomas in mice (1976) (0)
- Pancreatic lesions caused by ethionine or N methyl N nitrosourea in the guinea pig (1973) (0)
- Inductionof Liver Tumorsby Aflatoxin B1in the Tree Shrew (Tupalagus), a NonhumanPrimate1 (1976) (0)
- Hepatocarcinogenicity of Dehydroepiandrosterone in the Rat 1 (2006) (0)
- Title The peroxisomal enzyme L-PBE is required to preventthe dietary toxicity of medium-chain Fatty acids (2017) (0)
- Induction of peroxisome proliferation and peroxisomal beta oxidation system messenger rna levels by ciprofibrate in primary cultures of dog hepatocytes (1989) (0)
- Hemophilia a presenting with quadriparesis, a rare clinical presentation (2016) (0)
- Malignant Tumors in Rats Given Lasiocarpine 1 (2006) (0)
- Cloning and Identification o f M ouse Steroid Receptor C oactivator-1 (mSRC-1), as a Coactivator o f Peroxisom e Proliferator-Activated Receptor y (2016) (0)
- Gene expression for peroxisome-associated enzymes in hepatocellular carcinomas induced by ciprofibrate, a hypolipidemic compound (1986) (0)
- Abstract 1248: Critical Role of Peroxisome Proliferator-Activated Receptor Binding Protein in the Heart (2007) (0)
- Comparative study of the induction of hepatic peroxisomes and associated enzymes by a hypolipidemic drug and phthalate-ester plasticizers in Fisher 344 rats (1984) (0)
- Overexpression of PPAR (cid:68) regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D- forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal (cid:69) -oxidation system* (2003) (0)
- Transcription coactivator PBP/MED1 is required for diethylnitrosamine‐induced hepatocarcinogenesis in the mouse (2009) (0)
- ANTI DIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF Aconitum Ferox IN ALLOXAN INDUCED DIASEASED RATS (2016) (0)
- TGS1: a novel regulator of β-cell mass and function (2021) (0)
- Preparation of recombinant adenoviruses of PPARγ and its transcriptional coactivator MED1 and their biological function analysis (2015) (0)
- Transcriptional Regulation of Cidea in mouse liver by PPAR {alpha} and PPAR{gamma} (2006) (0)
- Development of hepatocellular carcinoma in mice with disrupted peroxisomal fatty acyl-CoA oxidase gene (1997) (0)
- THE RELEVANCE OF PEROXISOME PROLIFERATION AND CELL PROLIFERATION HEPATOCARCINOGENESIS* IN PEROXISOME PROLIFERATOR4NDUCED (1989) (0)
- Pancreatic Involution in the Rat (2007) (0)
- Med1 subunit of the mediator complex is phosphorylated by AMPK (2013) (0)
- Two-dimensional polyacrylamide gel electrophoretic analysis of [35S]methionine (35S-Met) labeled hepatocyte proteins reveals rapid induction of specific proteins by ciprofibrate, a peroxisome proliferator (1985) (0)
- Induction of liver tumours by 3'-methyl-dimethylaminoazobenzene (3'-Me-DAB) in rats chronically infected with Toxoplasma or Besnoitia. (1977) (0)
- Purification , properties , and immunocytochemical localization of human liver peroxisomal enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase ( fatty acid 13-oxidation / electron microscopy / rotary shadowing ) (0)
- Transformation of mammalian cells by overexpressing H 202-generating peroxisomal fatty acyl-CoA oxidase ( peroxisome proliferation / peroxisome proliferators / fatty acid a-oxidation ) (0)
- Reye's syndrome: report of cases and a review of literature. (1975) (0)
- Inductionand Originof Hepatocytes inRat Pancreas (2013) (0)
- Differential expression of nuclear receptor coregulators in mouse tissues (2006) (0)
- [Hyperlipidemia in hepatic MED1 deficient mice in response to fasting]. (2011) (0)
- Toxicological Implications of Peroxisome Proliferation (2020) (0)
- Angiosarcoma of the liver in guinea pigs induced by 2,2'-dihydroxy-di-N-propylnitrosamine: light and electron microscopic features (1977) (0)
- Perspective on hepatic peroxisomes and pancreatic hepatocytes (1994) (0)
- Peroxisome proliferator ciprofibrate inhibits the induction in rat liver of glutathione S-transferase activity by the antioxidant ethoxyqui (1984) (0)
- Quantitation of bovine liver catalase by single radial immunodiffusion. (1974) (0)
- Informal Discussion following the Paper by Reddy and Rao (1975) (0)
- Tissue distribution of peroxisome proliferator-activated receptor in the mouse (1994) (0)
- Increased resistance of peroxisome proliferator induced hepatic lesions to iron accumulation in rats (1985) (0)
- Quantitative changes in sets of proteins as markers of biological response. (1991) (0)
- PPAEα in the pathogenesis of fatty liver disease (2004) (0)
- Erratum: Transcription coactivator PBP, the peroxisome proliferator- activated receptor (PPAR)-binding protein, is required for PPARα-regulated gene expression in liver (Journal of Biological Chemistry (2004) 279 (24427-24434)) (2004) (0)
- Thioacetamide enhances development of neoplastic nodules and cirrhosis in the liver of rats fed lasiocarpine, a pyrrolizidine alkaloid (1976) (0)
- Transcriptional Regulation of Cidea in mouse liver by PPAR α and PPARγ (2006) (0)
- Separation and Characterization of Neoplastic Cell Subpopulations of a Transplantable Rat Pancreatic Acinar Carcinoma 1 (2006) (0)
- Stable Expression of Peroxisomal Fatty Acyl‐CoA Oxidase in Vitro a (1996) (0)
- Induction ofperoxisome proliferation andhepatic tumoursin C57BL/6Nmicebyciprofibrate, a hypolipidaemic compound (1988) (0)
- Mechanistic relevance of peroxisome proliferation to human cancer risk assessment (1998) (0)
- PAT5A: A partial agonist of PPARγ is a potent antidiabetic thiazolidinedione yet weakly adipogenic (2003) (0)
- Stimulation of catalase and carnitine acetyltransferase activities and peroxisome proliferation by 1 methyl 4 piperidyl bis (p chlorophenoxy) acetate (1975) (0)
- The Role of PRIP in Breast Cancer (2002) (0)
- Tra nspla n table Pan c rea tic A cin a r Ca rcin om a (1981) (0)
- Dose dependent increase of hepatic catalase and carnitine acetyltransferase activities in intact female rats fed clofibrate (1978) (0)
- Localization and Expression of the Eicosanoid Metabolizing P4501VA Gene Family in Rat Tissues and Hepatic Tumors (1991) (0)
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What Schools Are Affiliated With Janardan K. Reddy?
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