Jane A. McKeating
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British virologist
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Jane A. McKeatingbiology Degrees
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Biology
Jane A. McKeating's Degrees
- Bachelors Microbiology University of Manchester
- PhD Virology University of Oxford
Why Is Jane A. McKeating Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jane A. McKeating is a professor of molecular biology at Oxford University, and honorary professor at the University of Birmingham, England, where she worked as a professor of molecular virology until 2017. She is listed as a notable scientist in Thomson Reuters' Highly Cited Researchers 2014, ranking her among the top 1% most cited scientists.
Jane A. McKeating's Published Works
Published Works
- Complete Replication of Hepatitis C Virus in Cell Culture (2005) (2366)
- Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry (2007) (1282)
- Highly Permissive Cell Lines for Subgenomic and Genomic Hepatitis C Virus RNA Replication (2002) (1215)
- Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. (1999) (1093)
- Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles (2003) (877)
- EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy (2011) (661)
- Dissociation of gp120 from HIV-1 virions induced by soluble CD4. (1990) (612)
- Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge (2008) (594)
- Characterization of Hepatitis C Virus E2 Glycoprotein Interaction with a Putative Cellular Receptor, CD81 (1999) (524)
- Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro. (2006) (484)
- Neutralizing antibody response during acute and chronic hepatitis C virus infection. (2004) (462)
- Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo. (2007) (430)
- Hepatitis C Virus Glycoproteins Interact with DC-SIGN and DC-SIGNR (2003) (426)
- Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry (2006) (417)
- CD81 Is Required for Hepatitis C Virus Glycoprotein-Mediated Viral Infection (2004) (407)
- Hepatitis C virus cell‐cell transmission in hepatoma cells in the presence of neutralizing antibodies (2007) (392)
- Efficient Replication of Hepatitis C Virus Genotype 1a RNAs in Cell Culture (2003) (378)
- MAIT cells are activated during human viral infections (2016) (366)
- Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates (1992) (297)
- Initiation of Hepatitis C Virus Infection Is Dependent on Cholesterol and Cooperativity between CD81 and Scavenger Receptor B Type I (2006) (291)
- Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission (2010) (262)
- Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus andHost (2006) (261)
- Viral hepatitis and liver cancer (2017) (254)
- Identification of Amino Acid Residues in CD81 Critical for Interaction with Hepatitis C Virus Envelope Glycoprotein E2 (2000) (245)
- Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody (1991) (238)
- Claudin Association with CD81 Defines Hepatitis C Virus Entry (2010) (236)
- Differential loss of envelope glycoprotein gp120 from virions of human immunodeficiency virus type 1 isolates: effects on infectivity and neutralization (1991) (234)
- The V3 loops of the HIV-1 and HIV-2 surface glycoproteins contain proteolytic cleavage sites: a possible function in viral fusion? (1991) (231)
- The Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope Protein (2007) (223)
- An engineered poliovirus chimaera elicits broadly reactive HIV-1 neutralizing antibodies (1989) (223)
- Characterization of HIV‐1 neutralization escape mutants (1989) (218)
- Multiple effects of silymarin on the hepatitis C virus lifecycle (2010) (218)
- Hepatitis C virus infects the endothelial cells of the blood-brain barrier. (2012) (213)
- CD81 and Claudin 1 Coreceptor Association: Role in Hepatitis C Virus Entry (2008) (213)
- Subcellular Localization of Hepatitis C Virus Structural Proteins in a Cell Culture System That Efficiently Replicates the Virus (2006) (209)
- Humoral immune response in acute hepatitis C virus infection. (2005) (208)
- Binding of the Hepatitis C Virus E2 Glycoprotein to CD81 Is Strain Specific and Is Modulated by a Complex Interplay between Hypervariable Regions 1 and 2 (2003) (207)
- Functional analysis of hepatitis C virus E2 glycoproteins and virus-like particles reveals structural dissimilarities between different forms of E2. (2001) (207)
- Diverse Hepatitis C Virus Glycoproteins Mediate Viral Infection in a CD81-Dependent Manner (2004) (203)
- Functional Analysis of Cell Surface-Expressed Hepatitis C Virus E2 Glycoprotein (1999) (203)
- Inhibition of hepatitis C virus infection by anti‐claudin‐1 antibodies is mediated by neutralization of E2–CD81–Claudin‐1 associations (2010) (195)
- Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4 (1991) (188)
- Diverse CD81 Proteins Support Hepatitis C Virus Infection (2006) (182)
- Scavenger Receptor BI and BII Expression Levels Modulate Hepatitis C Virus Infectivity (2007) (177)
- Discordant role of CD4 T-cell response relative to neutralizing antibody and CD8 T-cell responses in acute hepatitis C. (2007) (177)
- Identification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing Antibodies (2008) (175)
- Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes. (2010) (173)
- HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex. (2013) (161)
- Oxidized low‐density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells (2006) (153)
- Characterization of neutralizing monoclonal antibodies to linear and conformation-dependent epitopes within the first and second variable domains of human immunodeficiency virus type 1 gp120 (1993) (149)
- Serum-Derived Hepatitis C Virus Infection of Primary Human Hepatocytes Is Tetraspanin CD81 Dependent (2007) (148)
- IFITM1 is a tight junction protein that inhibits hepatitis C virus entry†, ‡ (2012) (148)
- Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants. (1999) (145)
- Superinfection Exclusion in Cells Infected with Hepatitis C Virus (2007) (144)
- Hypoxia inducible factors in liver disease and hepatocellular carcinoma: current understanding and future directions. (2014) (143)
- Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors. (2011) (142)
- Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis (2012) (141)
- Beta 2 microglobulin enhances the infectivity of cytomegalovirus and when bound to the virus enables class I HLA molecules to be used as a virus receptor. (1987) (137)
- Tumour necrosis factors (alpha, beta) induced by HIV-1 in peripheral blood mononuclear cells potentiate virus replication. (1990) (136)
- Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells (2009) (136)
- HIV susceptibility conferred to human fibroblasts by cytomegalovirus-induced Fc receptor (1990) (134)
- Effect of Cell Polarization on Hepatitis C Virus Entry (2007) (125)
- Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels. (2018) (124)
- Functional Characterization of Intracellular and Secreted Forms of a Truncated Hepatitis C Virus E2 Glycoprotein (2000) (123)
- Polymersome-mediated delivery of combination anticancer therapy to head and neck cancer cells: 2D and 3D in vitro evaluation. (2014) (120)
- Hepatitis C virus receptor expression in normal and diseased liver tissue (2007) (117)
- The past, present and future of neutralizing antibodies for hepatitis C virus (2014) (115)
- Binding of Hepatitis C Virus E2 Glycoprotein to CD81 Does Not Correlate with Species Permissiveness to Infection (2000) (112)
- Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles. (2006) (112)
- Characterization of Infectious Retroviral Pseudotype Particles Bearing Hepatitis C Virus Glycoproteins (2004) (109)
- Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity (2009) (104)
- Hepatitis C virus and the brain (2012) (102)
- Genome-to-genome analysis highlights the impact of the human innate and adaptive immune systems on the hepatitis C virus (2017) (102)
- The role of the hepatitis C virus glycoproteins in infection (2000) (99)
- Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity (2008) (97)
- Characterization of recombinant gp120 and gp160 from HIV-1: binding to monoclonal antibodies and soluble CD4. (1990) (94)
- Hepatitis C virus association with peripheral blood B lymphocytes potentiates viral infection of liver-derived hepatoma cells. (2009) (93)
- Construction and characterization of chimeric hepatitis C virus E2 glycoproteins: analysis of regions critical for glycoprotein aggregation and CD81 binding. (2000) (91)
- Hepatitis C virus infection reduces hepatocellular polarity in a vascular endothelial growth factor-dependent manner. (2010) (90)
- Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment (2021) (90)
- Development of novel therapies for hepatitis C. (2010) (90)
- Synergistic interaction between ligands binding to the CD4 binding site and V3 domain of human immunodeficiency virus type I gpl20 (1992) (90)
- Hepatitis C virus envelope glycoprotein immunization of rodents elicits cross-reactive neutralizing antibodies. (2007) (88)
- Hepatitis C virus entry: beyond receptors (2012) (88)
- In vitro selection of a neutralization-resistant hepatitis C virus escape mutant (2008) (86)
- Cytomegalovirus in urine specimens has host beta 2 microglobulin bound to the viral envelope: a mechanism of evading the host immune response? (1987) (85)
- Cytomegalovirus strain AD169 binds beta 2 microglobulin in vitro after release from cells. (1987) (83)
- Characterization of neutralization epitopes in the V2 region of human immunodeficiency virus type 1 gp120: role of glycosylation in the correct folding of the V1/V2 domain (1995) (81)
- Clearance of persistent hepatitis C virus infection using a claudin-1-targeting monoclonal antibody (2015) (79)
- A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration (2012) (79)
- Insights From Deep Sequencing of the HBV Genome—Unique, Tiny, and Misunderstood (2018) (78)
- Structural Flexibility of a Conserved Antigenic Region in Hepatitis C Virus Glycoprotein E2 Recognized by Broadly Neutralizing Antibodies (2014) (77)
- Hepatitis C is associated with perturbation of intrahepatic myeloid and plasmacytoid dendritic cell function. (2007) (71)
- An enzyme-linked immunosorbent assay for antibodies to the envelope glycoproteins of divergent strains of HIV-1. (1989) (71)
- Interferon lambda 4 impacts the genetic diversity of hepatitis C virus (2019) (71)
- Hepatitis C virus (HCV)-specific immune responses of long-term injection drug users frequently exposed to HCV. (2008) (69)
- An alpaca nanobody inhibits hepatitis C virus entry and cell‐to‐cell transmission (2013) (69)
- Pharmacological characterization of the chemokine receptor, CCR5 (2002) (66)
- Enhancement of class I HLA antigen expression by cytomegalovirus: Role in amplification of virus infection (1988) (66)
- Immunization of human volunteers with hepatitis C virus envelope glycoproteins elicits antibodies that cross-neutralize heterologous virus strains. (2011) (65)
- Identification and characterization of monoclonal antibodies specific for polymorphic antigenic determinants within the V2 region of the human immunodeficiency virus type 1 envelope glycoprotein (1995) (65)
- Multidrug treatment with nelfinavir and cepharanthine against COVID-19 (2020) (64)
- Hepatitis C virus infection of neuroepithelioma cell lines. (2010) (64)
- Combined Adenovirus Vector and Hepatitis C Virus Envelope Protein Prime-Boost Regimen Elicits T Cell and Neutralizing Antibody Immune Responses (2014) (62)
- Structure and function of the HIV envelope (1989) (62)
- Hepatitis C virus and alanine aminotransferase kinetics following B-lymphocyte depletion with rituximab: evidence for a significant role of humoral immunity in the control of viremia in chronic HCV liver disease. (2007) (61)
- Naturally Occurring Antibodies That Recognize Linear Epitopes in the Amino Terminus of the Hepatitis C Virus E2 Protein Confer Noninterfering, Additive Neutralization (2011) (61)
- Identification of Amino Acid Residues in CD 81 Critical for Interaction with Hepatitis C Virus Envelope Glycoprotein E 2 (1999) (60)
- An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease (2021) (58)
- Mechanisms of viral entry: sneaking in the front door (2010) (58)
- Rat monoclonal antibodies to nonoverlapping epitopes of human immunodeficiency virus type 1 gp120 block CD4 binding in vitro. (1991) (56)
- Infection of brain cells by diverse human immunodeficiency virus isolates: role of CD4 as receptor. (1989) (53)
- Amino acid residues of the human immunodeficiency virus type I gp120 critical for the binding of rat and human neutralizing antibodies that block the gp120-sCD4 interaction. (1992) (52)
- Resistance of a human serum-selected human immunodeficiency virus type 1 escape mutant to neutralization by CD4 binding site monoclonal antibodies is conferred by a single amino acid change in gp120 (1993) (52)
- The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication (2019) (52)
- Hepatitis C virus entry and neutralization. (2008) (51)
- An immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 (HXB2-Env:Ala 582(-->Thr)) decreases viral neutralization by monoclonal antibodies to the CD4-binding site. (1993) (51)
- Activated Macrophages Promote Hepatitis C Virus Entry in a Tumor Necrosis Factor-Dependent Manner (2014) (50)
- The C-terminal region of the hepatitis C virus E1 glycoprotein confers localization within the endoplasmic reticulum. (1999) (50)
- Hepatoma Cell Density Promotes Claudin-1 and Scavenger Receptor BI Expression and Hepatitis C Virus Internalization (2009) (50)
- Hepatitis C virus entry and the tetraspanin CD81. (2011) (49)
- Evaluation of human and simian immunodeficiency virus plaque and neutralization assays. (1989) (49)
- Functional characterization of the V1V2 region of human immunodeficiency virus type 1. (1996) (48)
- Entry of hepatitis B and C viruses - recent progress and future impact. (2014) (47)
- Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells (2020) (47)
- Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication. (2017) (46)
- Hepatoma polarization limits CD81 and hepatitis C virus dynamics (2012) (46)
- Monoclonal antibodies to the C4 region of human immunodeficiency virus type 1 gp120: use in topological analysis of a CD4 binding site. (1992) (44)
- The role of the humoral immune response in HIV infection (1996) (43)
- Interplay between circadian clock and viral infection (2017) (43)
- Passage of HIV-1 molecular clones into different cell lines confers differential sensitivity to neutralization. (1997) (43)
- The Circadian Clock and Viral Infections (2020) (42)
- Expression of HIV-1 envelope glycoproteins by Semliki Forest virus vectors. (1993) (41)
- Glucocorticoids promote Von Hippel Lindau degradation and Hif-1α stabilization (2017) (41)
- Length polymorphism within the second variable region of the human immunodeficiency virus type 1 envelope glycoprotein affects accessibility of the receptor binding site (1997) (40)
- Further characterization of an antigenic site of HIV-1 gp120 recognized by virus neutralizing human monoclonal antibodies. (1993) (40)
- Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS (2020) (39)
- Identification of a monoclonal antibody to abscission tissue that recognises xylose/fucose-containing N-linked oligosaccharides from higher plants (1988) (38)
- Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint (2021) (37)
- Structural characterization of recombinant human CD81 produced in Pichia pastoris (2008) (37)
- Development of a Neutralizing Antibody Response during Acute Primary Human Immunodeficiency Virus Type 1 Infection and the Emergence of Antigenic Variants (1998) (37)
- IGHV1-69 B Cell Chronic Lymphocytic Leukemia Antibodies Cross-React with HIV-1 and Hepatitis C Virus Antigens as Well as Intestinal Commensal Bacteria (2014) (36)
- Bioportide: an emergent concept of bioactive cell-penetrating peptides (2012) (36)
- Recombinant CD4-selected human immunodeficiency virus type 1 variants with reduced gp120 affinity for CD4 and increased cell fusion capacity (1991) (36)
- Detection of cytomegalovirus by ELISA in urine samples is inhibited by β2 microglobulin (1986) (36)
- Detection of cytomegalovirus in urine samples by enzyme‐linked immunosorbent assay (1985) (36)
- Hepatitis C Virus Envelope Glycoprotein Fitness Defines Virus Population Composition following Transmission to a New Host (2012) (35)
- Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes (2016) (34)
- Prevalence of a V2 epitope in clade B primary isolates and its recognition by sera from HIV-1-infected individuals. (1997) (34)
- Hepatitis C virus entry: possible targets for therapy (2008) (34)
- In silico directed mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface (2012) (34)
- Detection of cytomegalovirus by DNA-DNA hybridization employing probes labelled with 32-phosphorus or biotin. (1985) (33)
- Primary hepatocytes as targets for Hepatitis C virus replication (2008) (32)
- Human immunodeficiency viruses: neutralization and receptors. (1988) (32)
- N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection (2017) (32)
- Monoclonal anti‐envelope antibody AP33 protects humanized mice against a patient‐derived hepatitis C virus challenge (2016) (32)
- The Measles Virus Receptor SLAMF1 Can Mediate Particle Endocytosis (2017) (32)
- Hepatitis C virus glycoprotein E2 binding to CD81: the role of E1E2 cleavage and protein glycosylation in bioactivity. (2000) (30)
- Functional Analysis of Claudin-6 and Claudin-9 as Entry Factors for Hepatitis C Virus Infection of Human Hepatocytes by Using Monoclonal Antibodies (2013) (30)
- Truncated gp120 envelope glycoprotein of human immunodeficiency virus 1 elicits a broadly reactive neutralizing immune response. (2002) (29)
- High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease (2017) (28)
- Cholesterol-modifying drugs in COVID-19 (2020) (28)
- Vaginal immunization of rats with a synthetic peptide from human immunodeficiency virus envelope glycoprotein. (1992) (28)
- Paracrine Signals From Liver Sinusoidal Endothelium Regulate Hepatitis C Virus Replication (2013) (28)
- Regulated expression vectors demonstrate cell-type-specific sensitivity to human immunodeficiency virus type 1 Nef-induced cytostasis. (1997) (28)
- Comparison of nucleic acid and protein immunization for induction of antibodies specific for HIV‐1 gp120 (1997) (27)
- Early infection events highlight the limited transmissibility of hepatitis C virus in vitro. (2013) (26)
- HIV-1 neutralization directed to epitopes other than linear V3 determinants. (1991) (26)
- The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells (2021) (26)
- Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant (2015) (26)
- Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication (2020) (25)
- Time of Day of Vaccination Affects SARS-CoV-2 Antibody Responses in an Observational Study of Health Care Workers (2021) (25)
- Chimeric viruses expressing primary envelope glycoproteins of human immunodeficiency virus type I show increased sensitivity to neutralization by human sera. (1996) (25)
- Deep sequencing of hepatitis C virus reveals genetic compartmentalization in cerebrospinal fluid from cognitively impaired patients (2016) (25)
- Effect of scavenger receptor class B type I antagonist ITX5061 in patients with hepatitis C virus infection undergoing liver transplantation (2016) (25)
- Soluble CD4 and CD4 immunoglobulin-selected HIV-1 variants: a phenotypic characterization. (1993) (23)
- Antigenicity of truncated forms of the human immunodeficiency virus type 1 envelope glycoprotein. (1996) (23)
- Clocks, Viruses, and Immunity: Lessons for the COVID-19 Pandemic (2021) (22)
- Synergistic interaction between ligands binding to the CD4 binding site and V3 domain of human immunodeficiency virus type I gp120. (1992) (21)
- Immunogenicity of full length and truncated forms of the human immunodeficiency virus type I envelope glycoprotein. (1996) (21)
- A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis (2019) (19)
- Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences (2022) (19)
- Circadian control of hepatitis B virus replication (2021) (19)
- Antigenic variation in HIV. (1990) (18)
- Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter (2021) (17)
- Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion (2011) (17)
- TNF superfamily members promote hepatitis C virus entry via an NF-κB and myosin light chain kinase dependent pathway (2017) (16)
- Lentiviral hepatitis B pseudotype entry requires sodium taurocholate co-transporting polypeptide and additional hepatocyte-specific factors. (2016) (16)
- Hepatitis C virus infection is associated with hepatic and adipose tissue insulin resistance that improves after viral cure (2019) (16)
- Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway (2019) (16)
- Hypoxic microenvironment shapes HIV-1 replication and latency (2020) (15)
- Metallo supramolecular cylinders inhibit HIV-1 TAR-TAT complex formation and viral replication in cellulo (2018) (15)
- The CCCTC-binding factor CTCF represses hepatitis B virus enhancer I and regulates viral transcription (2020) (14)
- Association between a defective CCR-5 gene and progression to disease in HIV infection. (1998) (14)
- A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81 (2017) (14)
- CPF-DD is an inhibitor of infection by human immunodeficiency virus and other enveloped viruses in vitro. (1992) (12)
- Differential effects of dehydroepiandrosterone and deoxyribonucleosides on DNA synthesis and de novo cholesterogenesis in hepatocarcinogenesis in rats. (1991) (12)
- Synchronised infection identifies early rate-limiting steps in the hepatitis B virus life cycle (2020) (12)
- Production, Purification and Characterization of Recombinant, Full-Length Human Claudin-1 (2013) (12)
- The History of HIV-1 Biological Phenotypes Past , Present and Future (1998) (12)
- In vitro veritas? The challenges of studying hepatitis C virus infectivity in a test tube. (2007) (12)
- Diverse CD 81 Proteins Support Hepatitis C Virus Infection (2006) (12)
- Hypoxia‐Inducible Factor 1 Alpha–Mediated RelB/APOBEC3B Down‐regulation Allows Hepatitis B Virus Persistence (2021) (12)
- CYTOMEGALOVIRUS AND β2 MICROGLOBULIN IN URINE SPECIMENS: RECIPROCAL INTERFERENCE IN THEIR DETECTION IS RESPONSIBLE FOR ARTIFACTUALLY HIGH LEVELS OF URINARY β2 MICROGLOBULIN IN INFECTED TRANSPLANT RECIPIENTS (1988) (11)
- Neutralization of human immunodeficiency virus (1992) (11)
- Differential effect of p7 inhibitors on hepatitis C virus cell-to-cell transmission☆ (2013) (11)
- A Cost-Effectiveness Analysis of Shortened Direct-Acting Antiviral Treatment in Genotype 1 Noncirrhotic Treatment-Naive Patients With Chronic Hepatitis C Virus (2019) (11)
- Construction and characterization of chimeric hepatitis C virus E 2 glycoproteins : analysis of regions critical for glycoprotein aggregation and CD 81 binding (11)
- An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease (2021) (11)
- Estimating hepatitis B virus cccDNA persistence in chronic infection† (2020) (11)
- A bile acid transporter as a candidate receptor for hepatitis B and D virus entry. (2013) (10)
- Identification of Amino Acid Residues Critical for Aggregation of Human CC Chemokines Macrophage Inflammatory Protein (MIP)-1α, MIP-1β, and RANTES (1999) (10)
- A Role for CD81 and Hepatitis C Virus in Hepatoma Mobility (2014) (10)
- Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models (2020) (10)
- The construction and characterization of poliovirus antigen chimeras presenting defined regions of the human T lymphocyte marker CD4. (1994) (9)
- Rituximab Treatment in Hepatitis C Infection: An In Vitro Model to Study the Impact of B Cell Depletion on Virus Infectivity (2011) (9)
- Oxygen Sensing and Viral Replication: Implications for Tropism and Pathogenesis (2020) (9)
- Biological consequences of human immunodeficiency virus type 1 envelope polymorphism: does variation matter? 1995 Fleming Lecture. (1996) (9)
- The complexities of hepatitis C virus entry. (2009) (8)
- Neutralization of virus. (1992) (8)
- Hepatitis C virus infection of cholangiocarcinoma cell lines (2015) (8)
- Herpesvirus Saimiri-Transformed Human CD4+ T-Cell Lines: an Efficient Target Cell System for the Analysis of Human Immunodeficiency Virus-Specific Cytotoxic CD8+T-Lymphocyte Activity (1998) (8)
- Antigenic Variation within the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120: Effects on Chemokine Receptor Utilization (2001) (8)
- Review article: HCV ? STAT-C era of therapy (2010) (8)
- Structural characterization of CD81-Claudin-1 hepatitis C virus receptor complexes. (2011) (8)
- A PCR assay to quantify patterns of HBV transcription (2019) (8)
- Inoculation of New World Primates With the Human Immunodeficiency Virus (1989) (8)
- P0676 : Clearance of persistent hepatitis c virus infection using a monoclonal antibody specific for tight junction protein claudin-1 (2015) (7)
- Daytime variation in hepatitis C virus replication kinetics following liver transplant. (2018) (7)
- The role of circadian clock pathways in viral replication (2022) (7)
- The role of the viral glycoprotein in HIV-1 persistence. (1999) (6)
- Type I interferon rapidly restricts infectious hepatitis C virus particle genesis (2014) (6)
- BASIC-LIVER, PANCREAS, AND BILIARY TRACT Discordant Role of CD4 T-Cell Response Relative to Neutralizing Antibody and CD8 T-Cell Responses in Acute Hepatitis C (2007) (6)
- Supramolecular Cylinders Target Bulge Structures in the 5′ UTR of the RNA Genome of SARS‐CoV‐2 and Inhibit Viral Replication (2021) (6)
- Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen (2018) (6)
- Over the fence or through the gate: how viruses infect polarized cells. (2012) (5)
- Mutant CD4 molecules with improved binding to HIV envelope protein gp120 selected by phage display. (1997) (5)
- Correction to ‘Viral hepatitis and liver cancer’ (2017) (5)
- Synchronized infection identifies early rate-limiting steps in the hepatitis B virus life cycle (2020) (4)
- Absolute quantitation of individual SARS-CoV-2 RNA molecules: a new paradigm for infection dynamics and variant differences (2021) (4)
- The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication (2019) (4)
- The effect of low-profile serine substitutions in the V3 loop of HIV-1 gp120 IIIB/LAI on the immunogenicity of the envelope protein. (1998) (4)
- Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure (2020) (4)
- O.174 Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus (2006) (4)
- Estimation of hepatitis B virus cccDNA persistence in chronic infection using within-host evolutionary rates (2020) (4)
- A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort (2016) (3)
- Daytime variation in hepatitis C virus replication kinetics following liver transplant (2018) (3)
- Hand Stitch, Perspectives (2012) (3)
- , between Hypervariable Regions 1 and 2 Is Modulated by a Complex Interplay Glycoprotein to CD 81 Is Strain Specific and Binding of the Hepatitis C Virus E 2 (2002) (3)
- Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents (2022) (3)
- Heterogeneous Claudin-1 Expression in Human Liver (2013) (3)
- HIV infectivity. (1991) (2)
- Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model (2022) (2)
- Memory cytotoxic SARS-CoV-2 spike protein-specific CD4+ T cells associate with viral control (2022) (2)
- Identification of claudin-1 as an essential cellular cell entry factor for hepatitis C virus (2006) (2)
- Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection (2015) (2)
- O.015 A phase 1 trial of a novel E1E2/MF59C.1 hepatitis C vaccine candidate in healthy HCV-negative adults (DMID 01-002) (2006) (2)
- Circadian regulation of SARS-CoV-2 infection in lung epithelial cells (2021) (2)
- Time of day of vaccination affects SARS-CoV-2 antibody responses in an observational study of healthcare workers (2021) (2)
- The Involvement of Tight Junction Protein Claudin-1 in Hepatitis C Virus Entry (2010) (2)
- CONFORMATIONAL GP120 NEUTRALIZATION EPITOPES ON HIV-1 (1991) (2)
- Effect of scavenger receptor B-I antagonist, ITX5061, on early hepatitis C virus kinetics in liver transplantation: results of a phase 1b clinical trial (2014) (2)
- HEPATITIS Oxidized Low-Density Lipoprotein Inhibits Hepatitis C Virus Cell Entry in Human Hepatoma Cells (2006) (2)
- Inflammatory Gene Expression Associates with Hepatitis B Virus cccDNA- but Not Integrant-Derived Transcripts in HBeAg Negative Disease (2022) (1)
- Scavenger receptor B-I antagonist ITX5061 modulates early HCV kinetics in patients undergoing liver transplantation: results of a phase Ib clinical trial (2013) (1)
- Machine Stitch: Perspectives (2011) (1)
- Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus and Host (cid:1) † (2006) (1)
- Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS (2020) (1)
- Hypoxic gene expression in chronic hepatitis B infected patients is not observed in state-of-art in vitro and mouse infection models (2020) (1)
- 58 HRas SIGNAL TRANSDUCTION MEDIATES HEPATITIS C VIRUS CELL ENTRY BY TRIGGERING THE ASSEMBLY OF THE HOST TETRASPANIN RECEPTOR COMPLEX (2013) (1)
- An ACAT inhibitor regulates SARS-CoV-2 replication and antiviral T cell activity (2022) (1)
- The Role of β2-Microglobulin and Class I HLA Heavy Chain in Cytomegalovirus Infection (1988) (1)
- Cost-Effectiveness Analysis of Baseline Testing for Resistance-Associated Polymorphisms to Optimize Treatment Outcome in Genotype 1 Noncirrhotic Treatment-Naïve Patients With Chronic Hepatitis C Virus (2018) (1)
- Are the Patterns of Cytomegalovirus Viral Load Seen After Solid Organ Transplantation Affected by Circadian Rhythm? (2022) (1)
- CD4 antagonists : Novel approaches in HIV chemotherapy (1992) (1)
- A Role for B Cells to Transmit Hepatitis C Virus Infection (2020) (1)
- HIV infactivity (1991) (1)
- 402 Human hepatic sinusoidal endothelial cells (HSEC) interact with hepatitis C virus (HCV) E2 glycoprotein via DCSign and Lsign (2004) (1)
- OP23 Vascular endothelial growth factor activation of liver sinusoidal endothelial cells via vascular endothelial growth factor receptor-2 regulates hepatocellular hepatitis C virus replication (2010) (1)
- Identification of Anti-COVID-19 Agents, Cepharanthine and Nelfinavir, and Their Potential Usage for Combination Treatment (2020) (1)
- Circadian regulation of human immunodeficiency virus type 1 replication (2022) (0)
- Detection of gp120 hiv 1 and antibodies to defined regions of gp120 in human serum correlation with hiv 1 neutralization (1989) (0)
- REVIEW Hepatitis C virus entry: beyond receptors (2011) (0)
- Lentiviral hepatitis B pseudotype entry requires NTCP and additional hepatocyte-specific factors (2016) (0)
- University of Birmingham Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection (2015) (0)
- 827 EXPERIMENTAL HCV VACCINE COMBINING ADENOVIRUS AND PROTEIN ELICITS POTENT T-CELL RESPONSES AND NEUTRALIZING ANTIBODIES IN RODENTS (2012) (0)
- Author response: Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences (2021) (0)
- therapy Hepatitis C virus entry: possible targets for (2010) (0)
- University of Birmingham Superinfection Exclusion in Cells Infected with Hepatitis C Virus (2007) (0)
- Desombere, I. et al. (2016) Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus (2015) (0)
- Hepatitis C virus kinetics after liver transplantation to study the role of a small molecule inhibitor of viral entry (2013) (0)
- Oxygen-Dependent Histone Lysine Demethylase 4 Restricts Hepatitis B Virus Replication (2022) (0)
- Impact of virus subtype and host IFNL4 genotype on large-scale RNA structure formation in the genome of hepatitis C virus (2020) (0)
- IDENTIFICATION OF EGFR SIGNALLING PATHWAYS MEDIATING HEPATITIS C VIRUS ENTRY (2011) (0)
- P206 Hepatitis C Virus Compartmentalisation: Unravelling Genetic Complexity Within The Liver (2014) (0)
- Hepatitis C virus infection of cholangiocarcinoma cell lines Short Title: HCV infects cholagiocarcinoma cells Article Type: Standard (2015) (0)
- The HCV Envelope Glycoprotein Down-Modulates NF-κB Signalling and Associates With Stimulation of the Host Endoplasmic Reticulum Stress Pathway (2022) (0)
- Elimination of the immunodominant B cell epitopes on the V3 loop of HIV gp120 (1998) (0)
- Identification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing Antibodies (cid:1) (2008) (0)
- 7 T CELLS FACILITATE HEPATITIS C VIRUS TRANSMISSION TO POLARISED LIVER AND BRAIN CELL LINES, REVEALING A NEW ROLE FOR VIRAL QUASISPECIES (2013) (0)
- SOLUBLE CD4 BINDING TO HIV-1 VIRIONS CAUSES GP120 TO DISSOCIATE FROM GP41 (1991) (0)
- gpl20 Important in CD4 Binding and Human Immunodeficiency Virus Type (0)
- Estimating hepatitis B virus cccDNA persistence in chronic infection (2020) (0)
- 5[beta]-reductase (AKR1D1) is a regulator of glucose homeostasis in human hepatocytes and development of model systems to define its role in metabolic liver disease (2016) (0)
- SUBSTITUTION OF PBMC-DERIVED GP120 CODING SEQUENCES INTO AN INFECTIOUS MOLECULAR CLONE OF HIV-1 (1993) (0)
- CD4 antagonists. (1992) (0)
- Author Correction: Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models (2020) (0)
- Oxygenation and miR138-5 p act as rheostats in APOBEC3B-mediated Hepatitis B Virus control (2020) (0)
- P97 Lymphocyte-hepatocyte interactions: hepatitis C virus changes the rules (2011) (0)
- A non-Hodgkin's lymphoma immunoglobulin binds to the envelope 2 (E2) glycoprotein of hepatitis C virus (2001) (0)
- Full Title: Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection Short Title: Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection (2015) (0)
- Glucocorticoids promote Von Hippel Lindau (pVHL) degradation and Hif-1α stabilization (2017) (0)
- VIRAL HEPATITIS Paracrine Signals From Liver Sinusoidal Endothelium Regulate Hepatitis C Virus Replication (2014) (0)
- Hypoxia dampens innate immune signalling at early time points and increases Zika virus replication in iPSC-derived macrophages (2023) (0)
- 1566. Is Primary CMV Infection Post-transplant Influenced by Circadian Rhythms? (2018) (0)
- Using Monoclonal Antibodies Virus Infection of Human Hepatocytes by Claudin-9 as Entry Factors for Hepatitis C Functional Analysis of Claudin-6 and (2014) (0)
- The Role of CD4 Antigen in HIV Infection (1989) (0)
- University of Birmingham Primary hepatocytes as targets for hepatitis C virus replication. (2009) (0)
- Sleep and circadian rhythm disruption alters the lung transcriptome to predispose to viral infection (2022) (0)
- Hypoxic microenvironment shapes HIV-1 replication and latency (2020) (0)
- The construction and characterization of poliovirus antigen chimeras presenting defined regions of the human T lymphocyte marker CD 4 (2007) (0)
- P188 A HIGH-THROUGHPUT HDV INFECTION MODEL SYSTEM FOR SCREENING OF ANTIVIRALS AND HOST-TARGETING COMPOUNDS (2014) (0)
- P147 CD4+ T CELL EGRESS THROUGH HEPATIC EPITHELIA HAS PROFOUND IMPLICATIONS FOR PHENOTYPE AND FUNCTION (2014) (0)
- Editorial overview - virus entry: towards reality - refining models of virus entry. (2014) (0)
- Model systems to define the role of AKR1D1 in metabolic liver disease (2015) (0)
- Metallo supramolecular cylinders inhibit HIV-1 TAR-TAT complex formation and viral replication in cellulo (2018) (0)
- P622 MODELLING HCV REPLICATION IN AN INFLAMED LIVER ENVIRONMENT: A NEW ROLE FOR STROMAL EXPRESSED VAP-1 TO REGULATE VIRAL REPLICATION (2014) (0)
- An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity. (2023) (0)
- 1374 LYMPHOCYTE-HEPATOCYTE INTERACTIONS: HEPATITIS C VIRUS CHANGES THE RULES (2011) (0)
- P140 MODELLING THE LIVER IMMUNE MICROENVIRONMENT: FACTORS THAT DEFINE ANTIVIRAL ACTIVITY OF T CELLS (2014) (0)
- New Host Composition following Transmission to a Fitness Defines Virus Population Hepatitis C Virus Envelope Glycoprotein (2012) (0)
- CHARACTERIZATION OF A HUMAN SERUM SELECTED HIV-1 ESCAPE MUTANT RESISTANT TO NEUTRALIZATION BY MONOCLONAL-ANTIBODIES MAPPING TO THE CD4 BINDING-SITE OF GP120 (1993) (0)
- Hypoxia is more than HIFs. (2022) (0)
- Time-of-Day Variation in SARS-CoV-2 RNA Levels during the Second Wave of COVID-19 (2022) (0)
- Surface Sensibilities: Utilising machine stitch to render surface and mark-making (2010) (0)
- Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway (2019) (0)
- Monoclonal antibodies that target the hepatitis C virus envelope proteins prevent in vivo infection of an escape variant isolated from a liver transplant patient (2012) (0)
- P191 HEPATITIS B AND C VIRUS PROMOTE CROSSTALK BETWEEN HYPOXIA AND GLUCOCORTICOID SIGNALLING PATHWAYS TO RE-PROGRAMME HEPATOCYTE METABOLISM AND TO EVADE HOST INTERFERONS (2014) (0)
- HIV-1 epitope expression on a chimaeric poliovirus vaccine vector (1989) (0)
- TARGETING HEPATOCYTE RECEPTOR TYROSINE KINASES BY ERLOTINIB AND INHIBITION OF HEPATITIS C VIRUS INFECTION IN VIVO (2010) (0)
- Response : Receptor-Mediated Activation of Immunodeficiency Viruses in Viral Fusion (1991) (0)
- An Emerging Image (2010) (0)
- Lymphocyte interactions with hepatocytes: distinct mechanisms for T and B cells (2011) (0)
- Author response: Interferon lambda 4 impacts the genetic diversity of hepatitis C virus (2019) (0)
- University of Birmingham High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end stage liver disease (2016) (0)
- of Birmingham Persistent hepatitis C virus infection in vitro: Coevolution of virus and host (2006) (0)
- Unravelling the circadian transcriptome and epigenome of the human liver (2022) (0)
- University of Birmingham Neutralizing antibody response during acute and chronic hepatits C virus infection (2004) (0)
- Enhancement of BRET 2 Assay Robustness and Handling Utilizing the PerkinElmer EnVision Plate (2015) (0)
- The Complexities of Hepatitis C Virus Entry (2009) (0)
- 1152 HEPATITIS C VIRUS ENTRY INTO HUMAN HEPATOCYTES IS DEPENDENT ON CLAUDIN-1 BUT NOT ON CLAUDIN-6 AND CLAUDIN-9 (2013) (0)
- Investigations into the receptor requirements of Hepatitis C Virus (HCV) pseudoparticles and cell culture grown virions (2006) (0)
- University of Birmingham Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies (2015) (0)
- THE FIRST AND 2ND VARIABLE REGIONS OF HIV-1 GP120 AFFECT THE ABILITY OF THE ENVELOPE GLYCOPROTEIN TO BIND CD4 (1995) (0)
- Comment on : 1 Sodium taurocholate cotransporting polypeptide is a functional receptor for 2 human hepatitis B and D virus (2013) (0)
- HIV TARGET-CELL INTERACTIONS (1990) (0)
- Pharmacological analysis of CCR5 receptors using S-35 -GTP gamma S binding (2001) (0)
- 1178 A NANOBODY RECOGNIZING A NOVEL EPITOPE IN HEPATITIS C VIRUS GLYCOPROTEIN E2 BROADLY NEUTRALIZES VIRUS ENTRY AND INHIBITS CELL–CELL TRANSMISSION (2013) (0)
- University of Birmingham Diverse CD81 Proteins Support Hepatitis C Virus Infection (2006) (0)
- Interplay between circadian clock and viral infection (2017) (0)
- P1265 UNDERSTANDING THE IMPACT OF AGE ON HEPATIC INNATE IMMUNE RESPONSES IN HEPATITIS C VIRUS PATHOGENESIS AND RESPONSE TO INTERFERON THERAPY (2014) (0)
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