Janet L. Smith
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American biologist
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Janet L. Smithbiology Degrees
Biology
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Genetics
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Molecular Biology
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Biology
Janet L. Smith's Degrees
- Bachelors Biology University of California, Berkeley
- Masters Genetics Stanford University
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Why Is Janet L. Smith Influential?
(Suggest an Edit or Addition)According to Wikipedia, Janet Louise Smith is the Margaret J. Hunter Collegiate Professor in the Life Sciences Institute, director of the Center for Structural Biology at the University of Michigan, professor of biological chemistry and biophysics at the University of Michigan, and research professor in the Life Sciences Institute. Additionally, she is the scientific director of The General Medical Sciences and Cancer Institutes’ structural biology facility at the Advanced Photon Source .
Janet L. Smith's Published Works
Published Works
- Structure of the Cytochrome b6f Complex of Oxygenic Photosynthesis: Tuning the Cavity (2003) (721)
- A protein catalytic framework with an N-terminal nucleophile is capable of self-activation (1995) (603)
- A New Generation of Crystallographic Validation Tools for the Protein Data Bank (2011) (390)
- Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System (2014) (255)
- Structure of a modular polyketide synthase (2014) (250)
- The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families (1996) (217)
- The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation. (2004) (217)
- The Dictyostelium Kinome—Analysis of the Protein Kinases from a Simple Model Organism (2006) (169)
- Structural rearrangements of a polyketide synthase module during its catalytic cycle (2014) (163)
- A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium (2002) (162)
- Transmembrane traffic in the cytochrome b6f complex. (2006) (161)
- Structure of the Flavivirus Helicase: Implications for Catalytic Activity, Protein Interactions, and Proteolytic Processing (2005) (153)
- Metamorphic enzyme assembly in polyketide diversification (2009) (150)
- Micro-crystallography comes of age. (2012) (144)
- Catalytic Core of Alphavirus Nonstructural Protein nsP4 Possesses Terminal Adenylyltransferase Activity (2006) (139)
- Structure of the Rift Valley fever virus nucleocapsid protein reveals another architecture for RNA encapsidation (2010) (128)
- Extended surface for membrane association in Zika virus NS1 structure (2016) (127)
- Characterization of purified Sindbis virus nsP4 RNA-dependent RNA polymerase activity in vitro. (2009) (115)
- Radiation damage in protein crystals is reduced with a micron-sized X-ray beam (2011) (114)
- GNAT-Like Strategy for Polyketide Chain Initiation (2007) (108)
- Structural basis for macrolactonization by the pikromycin thioesterase (2006) (101)
- Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains. (2009) (98)
- Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway. (2010) (95)
- Functional Characterization of cis and trans Activity of the Flavivirus NS2B-NS3 Protease* (2007) (94)
- Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine β-synthase (2010) (92)
- Crystal Structure of Imidazole Glycerol Phosphate Synthase: A Tunnel through a (β/α)8 Barrel Joins Two Active Sites (2001) (92)
- A defined protein–detergent–lipid complex for crystallization of integral membrane proteins: The cytochrome b6f complex of oxygenic photosynthesis (2003) (91)
- Cyanobacterial polyketide synthase docking domains: a tool for engineering natural product biosynthesis. (2013) (91)
- Phleboviruses encapsidate their genomes by sequestering RNA bases (2012) (85)
- Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences (2019) (85)
- Identification of four candidate cGMP targets in Dictyostelium (2002) (84)
- Mini-beam collimator enables microcrystallography experiments on standard beamlines. (2009) (81)
- Crystal structure of glutamine phosphoribosylpyrophosphate amidotransferase from Escherichia coli (1998) (81)
- Structure and Function of the Glutamine Phosphoribosylpyrophosphate Amidotransferase Glutamine Site and Communication with the Phosphoribosylpyrophosphate Site* (1996) (80)
- Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis. (2009) (78)
- Conformational switch triggered by α-ketoglutarate in a halogenase of curacin A biosynthesis (2010) (77)
- In trypanosomes the homolog of the largest subunit of RNA polymerase II is encoded by two genes and has a highly unusual C-terminal domain structure (1989) (76)
- Molecular Characterization of Calmodulin Trapping by Calcium/Calmodulin-dependent Protein Kinase II* (2001) (75)
- Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels (2006) (71)
- Structural Basis of Multifunctionality in a Vitamin B12-processing Enzyme* (2011) (70)
- Insights into the reactivation of cobalamin-dependent methionine synthase (2009) (69)
- Signaling pathways regulating Dictyostelium myosin II (2004) (69)
- Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis (2011) (67)
- Toward understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerolphosphate synthase: crystal structures of a ternary complex and the free enzyme. (2003) (64)
- Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic Pathway* (2009) (63)
- Automated sample-scanning methods for radiation damage mitigation and diffraction-based centering of macromolecular crystals. (2011) (63)
- A 7 µm mini-beam improves diffraction data from small or imperfect crystals of macromolecules (2008) (60)
- Mocr: a novel fusion tag for enhancing solubility that is compatible with structural biology applications. (2009) (59)
- Identification of Inhibitors of Yellow Fever Virus Replication Using a Replicon-Based High-Throughput Assay (2009) (58)
- Cytochrome bc complexes: a common core of structure and function surrounded by diversity in the outlying provinces. (2004) (55)
- Evolution of photosynthesis: time-independent structure of the cytochrome b6f complex. (2004) (55)
- Substrate-induced changes in the ammonia channel for imidazole glycerol phosphate synthase. (2003) (55)
- Function and Structure of MalA/MalA', Iterative Halogenases for Late-Stage C-H Functionalization of Indole Alkaloids. (2017) (54)
- Characterization and Crystallization of the Lumen Side Domain of the Chloroplast Rieske Iron-Sulfur Protein* (1996) (54)
- A New Arrangement of (β/α)8 Barrels in the Synthase Subunit of PLP Synthase*♦ (2005) (54)
- Structural and stereochemical analysis of a modular polyketide synthase ketoreductase domain required for the generation of a cis-alkene. (2013) (52)
- Dual Role for the Glutamine Phosphoribosylpyrophosphate Amidotransferase Ammonia Channel (2000) (51)
- Structure‐guided insights on the role of NS1 in flavivirus infection (2015) (51)
- Metal active site elasticity linked to activation of homocysteine in methionine synthases (2008) (51)
- Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor. (2012) (48)
- Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction (2021) (47)
- Crystal Structure of the ECH2 Catalytic Domain of CurF from Lyngbya majuscula (2007) (47)
- HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry (2018) (46)
- An Enzyme Assembly Line (2008) (44)
- Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor* (2011) (44)
- Role for Conserved Residues of Sindbis Virus Nonstructural Protein 2 Methyltransferase-Like Domain in Regulation of Minus-Strand Synthesis and Development of Cytopathic Infection (2008) (43)
- Kinannote, a computer program to identify and classify members of the eukaryotic protein kinase superfamily (2013) (43)
- APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA (2017) (42)
- Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase. (2010) (41)
- Structure of trimeric haemerythrin (1983) (40)
- Complete Genome Sequences of Bacillus subtilis subsp. subtilis Laboratory Strains JH642 (AG174) and AG1839 (2014) (40)
- JBluIce-EPICS control system for macromolecular crystallography. (2011) (39)
- Functional Dissection of the Bacillus subtilis pur Operator Site (2003) (39)
- Structure of the cytochrome b6f complex: new prosthetic groups, Q-space, and the ‘hors d’oeuvres hypothesis’ for assembly of the complex (2004) (38)
- Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels–Alderase (2019) (36)
- Insights into tRNA-dependent amidotransferase evolution and catalysis from the structure of the Aquifex aeolicus enzyme. (2009) (35)
- Thiosulfate sulfurtransferase-like domain–containing 1 protein interacts with thioredoxin (2018) (35)
- Heterologous production, purification and characterization of enzymatically active Sindbis virus nonstructural protein nsP1. (2011) (34)
- Targeting phosphoinositide 3-kinase δ for allergic asthma. (2012) (32)
- Differential functional properties of calmodulin-dependent protein kinase IIgamma variants isolated from smooth muscle. (2003) (32)
- Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase. (2016) (31)
- The Purine Repressor of Bacillus subtilis: a Novel Combination of Domains Adapted for Transcription Regulation (2003) (31)
- Structural and dynamical rationale for fatty acid unsaturation in Escherichia coli (2019) (31)
- Structure and activity of DmmA, a marine haloalkane dehalogenase (2012) (31)
- Use of massively multiple merged data for low-resolution S-SAD phasing and refinement of flavivirus NS1. (2014) (30)
- Structural basis of functional group activation by sulfotransferases in complex metabolic pathways. (2012) (30)
- Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis. (2016) (30)
- Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate (2016) (26)
- Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis (2018) (26)
- Architecture of the polyketide synthase module: surprises from electron cryo-microscopy. (2015) (26)
- Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing (2016) (26)
- Lipid-based vaccine nanoparticles for induction of humoral immune responses against HIV-1 and SARS-CoV-2 (2020) (25)
- Functional Characterization of a Dehydratase Domain from the Pikromycin Polyketide Synthase. (2015) (25)
- Host Competence and Helicase Activity Differences Exhibited by West Nile Viral Variants Expressing NS3-249 Amino Acid Polymorphisms (2014) (24)
- Structure of the Nucleotide Complex of PyrR, the pyr Attenuation Protein from Bacillus caldolyticus, Suggests Dual Regulation by Pyrimidine and Purine Nucleotides (2005) (24)
- Identification of Potent and Selective RNA Antagonists of the IFN-γ-Inducible CXCL10 Chemokine† (2005) (24)
- Molecular basis for spirocycle formation in the paraherquamide biosynthetic pathway. (2019) (24)
- Determination of three-dimensional structure by multiwavelength anomalous diffraction: Current Opinion in Structural Biology 1991, 1:1002–1011 (1991) (24)
- Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase. (2015) (24)
- Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal (2016) (23)
- Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase–rhodanese fusion protein functions in sulfur assimilation (2017) (22)
- Stereodivergent, Chemoenzymatic Synthesis of Azaphilone Natural Products. (2019) (22)
- In Vitro Whole Genome DNA Binding Analysis of the Bacterial Replication Initiator and Transcription Factor DnaA (2015) (22)
- The apo and ternary complex structures of a chemotherapeutic target: human glycinamide ribonucleotide transformylase. (2005) (22)
- Crystal Structure of Imidazole Glycerol-phosphate Dehydratase (2004) (22)
- Genetic and biochemical interactions between the bacterial replication initiator DnaA and the nucleoid‐associated protein Rok in Bacillus subtilis (2017) (21)
- Protein-protein interactions in "cis-AT" polyketide synthases. (2018) (21)
- Dictyostelium discoideum has a single diacylglycerol kinase gene with similarity to mammalian theta isoforms. (2002) (21)
- Interdomain Signaling in Glutamine Phosphoribosylpyrophosphate Amidotransferase* (1999) (21)
- Preliminary x‐ray analysis of Escherichia coli GMP synthetase: Determination of anomalous scattering factors for a cysteinyl mercury derivative (1994) (21)
- Forming and inhibiting PRT active sites (1999) (20)
- A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit. (2017) (19)
- A Resource for Discovering Specific and Universal Biomarkers for Distributed Stem Cells (2011) (19)
- Insights from the sea: structural biology of marine polyketide synthases. (2012) (19)
- A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway. (2011) (19)
- Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module. (2018) (18)
- Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization. (2018) (17)
- Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway. (2018) (17)
- Clearing the skies over modular polyketide synthases. (2006) (17)
- Structural biology in the fight against COVID-19 (2021) (16)
- Genetic networks controlled by the bacterial replication initiator and transcription factor DnaA in Bacillus subtilis (2017) (16)
- Fast fluorescence techniques for crystallography beamlines. (2011) (16)
- Myosin light chain kinase A is activated by cGMP‐dependent and cGMP‐independent pathways (2006) (16)
- Cytochrome b6f Complex (2019) (16)
- cGMP signalling: different ways to create a pathway. (2003) (15)
- Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta. (2018) (15)
- Tylosin polyketide synthase module 3: stereospecificity, stereoselectivity and steady-state kinetic analysis of β-processing domains via diffusible, synthetic substrates (2015) (15)
- Sacrificial Cobalt-Carbon Bond Homolysis in Coenzyme B12 as a Cofactor Conservation Strategy. (2018) (15)
- A Stable Carbocyclic Analog of 5-Phosphoribosyl-1-pyrophosphate to Probe the Mechanism of Catalysis and Regulation of Glutamine Phosphoribosylpyrophosphate Amidotransferase (*) (1995) (15)
- Crystal Structures Capture Three States in the Catalytic Cycle of a Pyridoxal Phosphate (PLP) Synthase*♦ (2015) (14)
- A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit–Activating Enzyme CahJ (2018) (14)
- A new arrangement of (beta/alpha)8 barrels in the synthase subunit of PLP synthase. (2005) (14)
- Polyketide Intermediate Mimics as Probes for Revealing Cryptic Stereochemistry of Ketoreductase Domains (2014) (14)
- Design, expression, and purification of a Flaviviridae polymerase using a high‐throughput approach to facilitate crystal structure determination (2004) (14)
- New ligation-independent cloning vectors compatible with a high-throughput platform for parallel construct expression evaluation using baculovirus-infected insect cells. (2011) (14)
- Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase. (2016) (13)
- Temperature-Dependent Function of the Glutamine Phosphoribosylpyrophosphate Amidotransferase Ammonia Channel and Coupling with Glycinamide Ribonucleotide Synthetase in a Hyperthermophile (2000) (13)
- Context-Dependent Cleavage of the Capsid Protein by the West Nile Virus Protease Modulates the Efficiency of Virus Assembly (2015) (13)
- The cytochrome b6f complex. Novel aspects (1997) (13)
- A protein catalytic framework with an N-terminal nucleophile is capable of self-activation (1995) (12)
- Tightly integrated single- and multi-crystal data collection strategy calculation and parallelized data processing in JBluIce beamline control system (2014) (12)
- PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production. (2018) (12)
- Secret Life of Cytochrome bc1 (1998) (11)
- Micro‐Crystallography Developments at GM/CA‐CAT at the APS (2010) (10)
- Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis. (2019) (10)
- A biologist's guide to synchrotron facilities: the BioSync web resource. (2002) (10)
- Efficient merging of data from multiple samples for determination of anomalous substructure (2016) (10)
- Bisindolylmaleimide inhibitors of protein kinase C. Further conformational restriction of a tertiary amine side chain. (1994) (10)
- Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases. (2015) (9)
- Flexibility in Nucleic Acid Binding Is Central to APOBEC3H Antiviral Activity (2019) (9)
- Identification of potent and selective RNA antagonists of the IFN-gamma-inducible CXCL10 chemokine. (2005) (9)
- Regulatory Mechanism of Dictyostelium Myosin Light Chain Kinase A* (2004) (8)
- pyr RNA binding to the Bacillus caldolyticus PyrR attenuation protein – characterization and regulation by uridine and guanosine nucleotides (2008) (8)
- Mutational Analysis of Bacillus subtilisGlutamine Phosphoribosylpyrophosphate Amidotransferase Propeptide Processing (1999) (8)
- Predicted optical performance of the GM/CA@APS micro-focus beamline (2013) (8)
- Analysis of LexA binding sites and transcriptomics in response to genotoxic stress in Leptospira interrogans (2016) (8)
- Structural Basis of Polyketide Synthase O-Methylation. (2018) (8)
- Crystal Structure of Imidazole Glycerol-phosphate Dehydratase DUPLICATION OF AN UNUSUAL FOLD* (2004) (7)
- Erratum: Forming and inhibiting PRT active sites (1999) (6)
- Optical Performance of the GM/CA‐CAT Canted Undulator Beam lines for Protein Crystallography (2007) (6)
- Multiwavelength Anomalous Diffraction in Macromolecular Crystallography (1998) (6)
- Chemoenzymatic Dissection of Polyketide β-Branching in the Bryostatin Pathway. (2018) (6)
- [Structure and function of the cytochrome b6f complex of oxygenic photosynthesis]. (2004) (6)
- Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase. (2018) (5)
- A Phenotypic Screening Approach in Cord Blood–Derived Mast Cells to Identify Anti-Inflammatory Compounds (2013) (4)
- Announcement of the BioSync web site (2001) (4)
- Structure and Function of Hemerythrins (1985) (3)
- Characterization and Crystallization of A Highly Active Cytochrome b 6 f Complex from the Thermophilic Cyanobacterium, Mastigocladus Laminosus (1998) (3)
- CHAPTER 18:Recent Advances in the Structural and Mechanistic Biology of Non-Haem Fe(ii), 2-Oxoglutarate and O2-Dependent Halogenases (2015) (3)
- Identification of four candidate cGMP targets in (2002) (3)
- A general scheme for synthesis of substrate-based polyketide labels for acyl carrier proteins. (2010) (3)
- Levels of Circulating NS1 Impact West Nile Virus Spread to the Brain (2021) (3)
- Multiwavelength anomalous diffraction (2012) (3)
- Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine β-synthase (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 49 (20958-20963) DOI: 10.1073/pnas.1011448107) (2011) (2)
- HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry (2018) (2)
- Association and tautomeric equilibrium in β-keto acids (1985) (2)
- MAD and MIR (2006) (2)
- GM/CA canted undulator beamlines for protein crystallography (2005) (2)
- Biophysical methods Faster and bigger (1996) (2)
- Discrete disorder in protein crystals (1984) (2)
- A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA (2022) (1)
- Biophysical methods Advances in biophysical methods: the whole is greater than the sum of the parts (1998) (1)
- Multiple mechanisms for overcoming lethal over‐initiation of DNA replication (2021) (1)
- Crystal Structure of RNA-dependent RNA polymerase construct 1 (residues 71-679) from bovine viral diarrhea virus complexed with GTP (2004) (1)
- High Speed Gas Chromatography Using Liquid Crystalline Stationary Phases. (1985) (1)
- Multiple-wavelength phase determination in protein crystallography (1987) (1)
- Fast automated energy changes at synchrotron radiation beamlines equipped with transfocator or focusing mirrors (2022) (1)
- Biophysical methods Editorial overview (1993) (1)
- The Structure and Rearrangements of a Complete Polyketide Synthase Module During its Catalytic Cycle (2013) (1)
- PyrR, a bifunctional RNA-binding transcriptional attenuation protein and uracil phosphoribosyltransferase (1996) (1)
- Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent C-Methyltransferases. (2022) (1)
- The pre-clinical pharmacology of an inhaled PI3Kdelta inhibitor (2011) (1)
- Beneficial and detrimental genes in the cellular response to replication arrest (2021) (1)
- Flavivirus NS1: Structure and Function of an Enigmatic Virulence Factor (2022) (1)
- Proteins: ever larger, stranger and more dynamic. (2008) (1)
- Structure-function of two membrane proteins involved in electron transfer and ion translocation (1996) (0)
- Structure of PhqB Reductase Domain from Penicillium fellutanum (2019) (0)
- Pikromycin thioesterase in complex with product 10-deoxymethynolide (2006) (0)
- Sequence alignment of NS3-235–282 and helicase structure. (2014) (0)
- Crystal structure of PhqK in complex with malbrancheamide B (2020) (0)
- Flavin-dependent thymidylate synthase in complex with FAD and 2'-deoxyuridine-5'-monosulfate (2016) (0)
- Crystal structure of OxaC in complex with SAH and oxaline (2018) (0)
- Mobility and heterogeneity in protein structure as seen by diffraction (1986) (0)
- Zika virus non-structural protein 1 (NS1) (2016) (0)
- RIESKE SOLUBLE FRAGMENT FROM SPINACH (1998) (0)
- Crystal structure of persulfide dioxygenase-rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans (2017) (0)
- Crystal Structure of the ECH2 decarboxylase domain of CurF from Lyngbya majuscula (2007) (0)
- Crystal Structure of the Y82F variant of ECH2 decarboxylase domain of CurF from Lyngbya majuscula (2007) (0)
- Virulence factors and host defenses to viral infection (2017) (0)
- Campylobacter, chicken, and the regulatory performance standard (2013) (0)
- StiD O-MT residues 976-1266 (2018) (0)
- StiD O-MT residues 956-1266 (2018) (0)
- User Capabilities at the GM/Ca@APS Structural Biology Facility at the Advanced Photon Source (2020) (0)
- KHNYN is a zinc-finger antiviral protein (ZAP) co-factor that degrades ZAP-bound RNA (2022) (0)
- Crystal structure of RNA-dependent RNA polymerase construct 1 (residues 71-679) from BVDV (2004) (0)
- Crystal Structure of CahJ in Complex with Salicyl Adenylate (2018) (0)
- Crystal Structure of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ (Monoclinic) (2008) (0)
- StiE O-MT residues 961-1257 (2018) (0)
- Structure of Human ATP:Cobalamin Adenosyltransferase bound to ATP, Adenosylcobalamin, and Triphosphate (2018) (0)
- Crystal Structure of CahJ in Complex with 6-Methylsalicyl Adenylate (2018) (0)
- Structure of trna-dependent amidotransferase gatcab from aquifex aeolicus (2009) (0)
- Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half in a "His-On" conformation (2009) (0)
- Some Consequences of the High Resolution X-Ray Structure Analysis of Cytochrome f (1996) (0)
- Crystal structure of OxaC in complex with sinefungin and meleagrin (2018) (0)
- PyrR, the regulator of the pyrimidine biosynthetic operon in Bacillus caldolyticus (2004) (0)
- Editorial overview: Biophysical and molecular biological methods: Structure, dynamics, and single molecules. (2015) (0)
- Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin (2011) (0)
- Crystal structure of OxaC (2018) (0)
- Evolution of a bifunctional reductase/Diels–Alderase for fungal indole alkaloid biosynthesis (2019) (0)
- Crystal Structure of PyrR, The Regulator Of The Pyrimidine Biosynthetic Operon In Bacillus caldolyticus, UMP-bound form (2007) (0)
- Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half with AdoHcy bound (2009) (0)
- Automation and remote control at GM/CA CAT at the APS (2011) (0)
- Crystallography going MAD (1996) (0)
- N153Q mutant of cytochrome f from Chlamydomonas reinhardtii (2000) (0)
- Structure of MalC Reductase/Diels-Alderase from Malbranchea aurantiaca (2019) (0)
- Thioesterase from Tautomycetin Biosynthhetic Pathway (2010) (0)
- Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima complexed with Zn2+ (2008) (0)
- Determination of the structure of a large protein by MAD phasing: glutamine PRPP amidotransferase (1993) (0)
- Crystal Structure of CahJ in Complex with Salicylic Acid and AMP (2018) (0)
- FAD-dependent monooxygenase TropB from T. stipitatus (2019) (0)
- Self-processing cysteine-dependent N-terminal nucleophile hydrolases (2013) (0)
- Crystal structure of RoqN (2018) (0)
- Structure of PhqE Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and premalbrancheamide (2019) (0)
- Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans in complex with glutathione (2017) (0)
- Molecular Dynamics Simulations Reveal the Origins of the Distinct Activities and Substrate Selectivities of E. coli Dehydratases FabA and FabZ (2019) (0)
- Structural and Data Science-Driven Analysis to Assess Substrate Specificity of Diketopiperazine Reverse Prenyltransferase NotF: Cascade Biocatalytic Synthesis of (–)-Eurotiumin A (2021) (0)
- Crystal Structure of the ECH2 decarboxylase domain of CurF from Lyngbya majuscula, rhombohedral crystal form (2007) (0)
- APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA (2017) (0)
- Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (-)-Eurotiumin A. (2022) (0)
- Structure of a class 2 docking domain complex from modules CurG and CurH of the curacin A polyketide synthase (2014) (0)
- Structure of the synthase subunit of PLP synthase (2005) (0)
- Flavin-dependent thymidylate synthase in complex with FAD and deoxyuridine (2016) (0)
- Determination of crystal system and space group (2017) (0)
- Crystal Structure of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ and Homocysteine (Monoclinic) (2005) (0)
- Structure-Function of Two Membrane Protein Systems Involved in Transfer of Electrical Charge (1996) (0)
- Metal ion assembly of imidazole glycerol phosphate dehydratase (HIS3) from cryptoccocvs neoformans and saccharomyces cerevisiae (1997) (0)
- Crystal structure HpiC1 in P42 space group (2018) (0)
- Crystal Structure of SeMet-Substituted Apo-MMACHC (1-244), a human B12 processing enzyme (2011) (0)
- CRYSTAL STRUCTURE OF THE PURINE OPERON REPRESSOR OF BACILLUS SUBTILIS (2003) (0)
- The apo structure of human glycinamide ribonucleotide transformylase (2005) (0)
- A novel cGMP signaling pathway involved in myosin II regulation in Dictyostelium (2002) (0)
- Crystal structure of fused docking domains from PikAIII and PikAIV of the pikromycin polyketide synthase (2009) (0)
- Structural and functional studies on Bacillus subtilis YabJ, a member of the highly conserved YjgF family (2000) (0)
- Crystal structure HpiC1 W73M/K132M (2018) (0)
- Crystal structure of wild-type persulfide dioxygenase-rhodanese fusion protein from Burkholderia phytofirmans (2017) (0)
- Characterization of a protective antibody against dengue virus non-structural protein 1 (NS1) reveals critical domains required for NS1-triggered pathogenesis (2020) (0)
- ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH 2 AMP PER TETRAMER (1998) (0)
- Phylogenetic analyses of genomic WNV strains. (2014) (0)
- Small beams can play big roles in macromolecular crystallography (2008) (0)
- Characterization of Two Type I Polyketide Sythases Methyltransferase Domains from the Curacin A Biosynthetic Pathway (2015) (0)
- The structure of human glycinamide ribonucleotide transformylase in complex with alpha,beta-N-(hydroxyacetyl)-D-ribofuranosylamine and 10-formyl-5,8,dideazafolate (2005) (0)
- Probing radiation damage with a 1-micron beam (2008) (0)
- Radiation damage to protein crystals is reduced with a micron-sized X-ray beam (2011) (0)
- Molecular Choreography Of An Antibiotic Assembly Line (2016) (0)
- PYRR, THE BACILLUS SUBTILIS PYRIMIDINE BIOSYNTHETIC OPERON REPRESSOR, HEXAMERIC FORM (1998) (0)
- Structure of PhqE D166N Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and substrate (2019) (0)
- STRUCTURE OF CYTOCHROME F FROM CHLAMYDOMONAS REINHARDTII (2000) (0)
- Bacillus subtilis YABJ (1999) (0)
- Integrating disciplines in the natural products sciences: The story of Curacin A (2012) (0)
- Crystal Structure of Apo-MMACHC (1-244), a human B12 processing enzyme (2011) (0)
- Crystal Structure of CahJ in Complex with AMP (2018) (0)
- Germicidin synthase (Gcs) from Streptomyces coelicolor, a type III polyketide synthase (2012) (0)
- Image informatics and regulatory compliance (2003) (0)
- synthase module 3 : stereospeci fi city , stereoselectivity and steady-state kinetic analysis of b-processing domains via di ff usible , synthetic substrates † (2015) (0)
- Crystal Structure of CahJ in Complex with 5-Methylsalicyl Adenylate (2018) (0)
- Crystal Structure of the PurR complexed with cPRPP (2003) (0)
- Crystal structure of yellow fever virus NS3 helicase (2005) (0)
- Regulatory Mechanism of Dictyostelium Myosin Light Chain (2004) (0)
- Crystal structure of ligand free PhqK (2020) (0)
- Structure of a ketosynthase-acyltransferase di-domain from module CurL of the curacin A polyketide synthase (2014) (0)
- Structure of Human ATP:Cobalamin Adenosyltransferase bound to ATP, and Adenosylcobalamin (2018) (0)
- AprA Methyltransferase 2 - GNAT didomain in complex with SAH (2018) (0)
- Structural basis of the Cope rearrangement and C–C bond-forming cascade in hapalindole/fischerindole biogenesis (2017) (0)
- X-ray Studies Key to Nobel Prize Winning Work on Protein Receptors (2013) (0)
- The enzyme EryM gives a helping hand in natural product biosynthesis (2022) (0)
- Crystal Structure of RNA-dependent RNA polymerase construct 2 from bovine viral diarrhea virus (BVDV) (2004) (0)
- Genetic and biochemical interactions between the bacterial replication initiator DnaA and the nucleoid-associated protein Rok in (2016) (0)
- Pikromycin thioesterase with covalent pentaketide affinity label (2006) (0)
- Flavin-dependent thymidylate synthase R90A variant in complex with FAD and deoxyuridine monophosphate (2016) (0)
- Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction. (2023) (0)
- SeMet substituted StiD O-MT residues 976-1266 (2018) (0)
- A structure-based mechanism for HEXIM displacement from 7SK (2021) (0)
- Flavin-dependent thymidylate synthase R174A variant in complex with FAD and dUMP (2016) (0)
- Crystal structure of PhqK in complex with paraherquamide K (2020) (0)
- CBI Student Sabbatical Proposal : Characterization of docking domains from the curacin A biosynthetic pathway (2011) (0)
- Structural Investigation into the Mechanism of the Synthase Subunit of PLPS (2015) (0)
- Genetic and geographic distribution of NS3-249 polymorphisms (2014) (0)
- Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima complexed with Zn2+ and Homocysteine (2008) (0)
- The structure of erabutoxin B at 1.4 Å resolution. Structure/function relations including functional implications of the extensive water structure and side-chain disorder in the reactive site (1984) (0)
- LUMEN-SIDE DOMAIN OF REDUCED CYTOCHROME F AT-35 DEGREES CELSIUS (1997) (0)
- CYTOCHROME F FROM THE B6F COMPLEX OF PHORMIDIUM LAMINOSUM (1999) (0)
- crystal structure of yellow fever virus NS3 helicase complexed with ADP (2005) (0)
- Crystal Structure of Cytochrome b6f Complex from M.laminosus (2003) (0)
- Crystal structure HpiC1 F138S (2018) (0)
- Recent developments and future of the GM/CA@APS X-ray crystallography user facility at the Advanced Photon Source (2018) (0)
- Crystal Structure of CahJ in Complex with Benzoyl Adenylate (2018) (0)
- Structure Ways & Means A New Generation of Crystallographic Validation Tools for the Protein Data Bank (0)
- Crystal structure HpiC1 Y101F/F138S (2018) (0)
- Crystal structure of OxaG (2018) (0)
- Fungal Indole Alkaloid Biogenesis Through Evolution of a Bifunctional Reductase/Diels-Alderase (2018) (0)
- DdMLCK: Myosin light chain kinase-A (D. discoideum) (1995) (0)
- JBluIce-EPICS beamline control system for macromolecular crystallography (2011) (0)
- Proteins: stay tuned! (2006) (0)
- Pyrr, The Regulator Of The Pyrimidine Biosynthetic Operon In Bacillus caldolyticus, Nucleotide-bound form (2005) (0)
- Crystal Structure of macaque APOBEC3H in complex with RNA (2017) (0)
- Cover Feature: A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ (ChemBioChem 15/2018) (2018) (0)
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