Janet Thornton

Q: What Schools Are Affiliated With Janet Thornton

Janet Thornton is affiliated with the following schools: Birkbeck, University of London, Imperial College London, University College London, University of Nottingham, University of Illinois Urbana-Champaign, University of Texas Southwestern Medical Center, King's College London

Janet Thornton's AcademicInfluence.com Rankings

Janet Thornton

Biology

#568

World Rank

#1000

Historical Rank

Bioinformatics

World Rank

Historical Rank

Computational Biology

World Rank

Historical Rank

Molecular Biology

#62

World Rank

#63

Historical Rank

biology Degrees

Download Badge

Biology

Why Is Janet Thornton Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Dame Janet Maureen Thornton, is a senior scientist and director emeritus at the European Bioinformatics Institute , part of the European Molecular Biology Laboratory . She is one of the world's leading researchers in structural bioinformatics, using computational methods to understand protein structure and function. She served as director of the EBI from October 2001 to June 2015, and played a key role in ELIXIR.

(See a Problem?)

Janet Thornton's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

PROCHECK: a program to check the stereochemical quality of protein structures (1993) (21666)
The rapid generation of mutation data matrices from protein sequences (1992) (6355)
LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. (1995) (4632)
AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR (1996) (4608)
CATH--a hierarchic classification of protein domain structures. (1997) (2556)
Satisfying hydrogen bonding potential in proteins. (1994) (1958)
Principles of protein-protein interactions. (1996) (1619)
Stereochemical quality of protein structure coordinates (1992) (1502)
A new approach to protein fold recognition (1992) (1246)
Main-chain bond lengths and bond angles in protein structures. (1993) (1225)
Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span (2009) (1034)
PROMOTIF—A program to identify and analyze structural motifs in proteins (1996) (1033)
Influence of proline residues on protein conformation. (1991) (981)
Helix geometry in proteins. (1988) (917)
Metal ions in biological catalysis: from enzyme databases to general principles (2008) (853)
Amino acid?base interactions: a three-dimensional analysis of protein?DNA interactions at an atomic level (2001) (846)
A model recognition approach to the prediction of all-helical membrane protein structure and topology. (1994) (822)
Analysis and prediction of the different types of β-turn in proteins (1988) (794)
Diversity of protein–protein interactions (2003) (785)
A revised set of potentials for β‐turn formation in proteins (1994) (784)
Protein superfamilles and domain superfolds (1994) (699)
Disulphide bridges in globular proteins. (1981) (694)
Evolution of function in protein superfamilies, from a structural perspective. (2001) (687)
PDBsum: Structural summaries of PDB entries (2017) (660)
ProFunc: a server for predicting protein function from 3D structure (2005) (642)
Knowledge-based prediction of protein structures and the design of novel molecules (1987) (636)
The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data (2004) (631)
Analysis of protein-protein interaction sites using surface patches. (1997) (624)
Ion-pairs in proteins. (1983) (618)
One fold with many functions: the evolutionary relationships between TIM barrel families based on their sequences, structures and functions. (2002) (600)
An overview of the structures of protein-DNA complexes (2000) (586)
Structural characterisation and functional significance of transient protein-protein interactions. (2003) (559)
Analysis of catalytic residues in enzyme active sites. (2002) (558)
PQS: a protein quaternary structure file server. (1998) (552)
Continuous and discontinuous protein antigenic determinants (1986) (542)
Protein-protein interactions: a review of protein dimer structures. (1995) (537)
PDBsum: a Web-based database of summaries and analyses of all PDB structures. (1997) (533)
Evidence for lifespan extension and delayed age–related biomarkers in insulin receptor substrate 1 null mice (2008) (512)
Antibody-antigen interactions: contact analysis and binding site topography. (1996) (494)
Pi-pi interactions: the geometry and energetics of phenylalanine-phenylalanine interactions in proteins. (1991) (494)
Protein promiscuity and its implications for biotechnology (2009) (455)
Prediction of protein-protein interaction sites using patch analysis. (1997) (454)
β-Hairpin families in globular proteins (1985) (450)
CATH: comprehensive structural and functional annotations for genome sequences (2014) (423)
Protein clefts in molecular recognition and function. (1996) (421)
Conformation of beta-hairpins in protein structures. A systematic classification with applications to modelling by homology, electron density fitting and protein engineering. (1989) (413)
PDBsum more: new summaries and analyses of the known 3D structures of proteins and nucleic acids (2004) (407)
Protein-DNA interactions: A structural analysis. (1999) (406)
Protein-RNA interactions: a structural analysis. (2001) (393)
Genome-wide responses to mitochondrial dysfunction. (2001) (384)
Predicting Protein Ligand Binding Sites by Combining Evolutionary Sequence Conservation and 3D Structure (2009) (357)
Tess: A geometric hashing algorithm for deriving 3D coordinate templates for searching structural databases. Application to enzyme active sites (1997) (347)
Beta-turns and their distortions: a proposed new nomenclature. (1990) (346)
Molecular recognition. Conformational analysis of limited proteolytic sites and serine proteinase protein inhibitors. (1991) (336)
Protein–protein interfaces: Analysis of amino acid conservation in homodimers (2001) (336)
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (2009) (333)
Analysis of main chain torsion angles in proteins: prediction of NMR coupling constants for native and random coil conformations. (1996) (328)
Protein families and their evolution-a structural perspective. (2005) (314)
Predicting protein function from sequence and structural data. (2005) (308)
The CATH domain structure database: new protocols and classification levels give a more comprehensive resource for exploring evolution (2006) (306)
Construction, Visualisation, and Clustering of Transcription Networks from Microarray Expression Data (2007) (274)
Location of ‘continuous’ antigenic determinants in the protruding regions of proteins. (1986) (273)
The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis (2004) (273)
Discriminating between homodimeric and monomeric proteins in the crystalline state (2000) (267)
Protein-DNA interactions: amino acid conservation and the effects of mutations on binding specificity. (2002) (261)
Buried waters and internal cavities in monomeric proteins (1994) (259)
The CATH database: an extended protein family resource for structural and functional genomics (2003) (256)
PDBsum additions (2013) (255)
Amino/aromatic interactions in proteins: is the evidence stacked against hydrogen bonding? (1994) (253)
Derivation of 3D coordinate templates for searching structural databases: Application to ser‐His‐Asp catalytic triads in the serine proteinases and lipases (1996) (251)
Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. (2000) (239)
Structural families in loops of homologous proteins: automatic classification, modelling and application to antibodies. (1996) (234)
A revised set of potentials for beta-turn formation in proteins. (1994) (230)
The implications of alternative splicing in the ENCODE protein complement (2007) (227)
Identification and classification of protein fold families. (1993) (224)
From protein structure to function. (1999) (224)
A mutation data matrix for transmembrane proteins (1994) (223)
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures (2012) (222)
PROCHECK: validation of protein‐structure coordinates (2012) (220)
A method for localizing ligand binding pockets in protein structures (2005) (217)
Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C‐fibres by the endogenous autacoid 4‐oxononenal (2008) (217)
Protein function prediction using local 3D templates. (2005) (215)
From Structure to Function (2021) (214)
Evolutionary conservation of regulated longevity assurance mechanisms (2007) (212)
NUCPLOT: a program to generate schematic diagrams of protein-nucleic acid interactions. (1997) (209)
Protein folds and functions. (1998) (208)
The CATH classification revisited—architectures reviewed and new ways to characterize structural divergence in superfamilies (2008) (208)
A basic helix-loop-helix-leucine zipper transcription complex in yeast functions in a signaling pathway from mitochondria to the nucleus (1997) (206)
Shape variation in protein binding pockets and their ligands. (2007) (206)
From structure to function: Approaches and limitations (2000) (205)
Intrinsic φ,ψ propensities of amino acids, derived from the coil regions of known structures (1995) (202)
An algorithm for constraint-based structural template matching: application to 3D templates with statistical analysis (2003) (200)
Assigning genomic sequences to CATH (2000) (199)
Solvent-induced distortions and the curvature of α-helices (1983) (198)
Protein function annotation by homology-based inference (2009) (197)
Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins. (2003) (194)
Real spherical harmonic expansion coefficients as 3D shape descriptors for protein binding pocket and ligand comparisons (2005) (194)
Prepublication data sharing (2009) (190)
Understanding nature's catalytic toolkit. (2005) (187)
Using a neural network and spatial clustering to predict the location of active sites in enzymes. (2003) (186)
The structural basis of allosteric regulation in proteins (2009) (184)
The interaction between phenylalanine rings in proteins (1985) (184)
Distributions of water around amino acid residues in proteins. (1988) (183)
Amino and carboxy-terminal regions in globular proteins. (1983) (175)
Comparison of conformational characteristics in structurally similar protein pairs (1993) (174)
Validation of protein models derived from experiment. (1998) (173)
Protein folds, functions and evolution. (1999) (173)
The CATH Database provides insights into protein structure/function relationships (1999) (172)
Determinants of strand register in antiparallel β‐sheets of proteins (1998) (168)
Identification, classification, and analysis of beta‐bulges in proteins (1993) (168)
Plasticity of enzyme active sites. (2002) (168)
A topological model for hepatitis B surface antigen. (1992) (167)
The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes (2013) (166)
Domain assignment for protein structures using a consensus approach: Characterization and analysis (1998) (164)
Conservation helps to identify biologically relevant crystal contacts. (2001) (162)
On the conformation of proteins: The handedness of the β-strand-α-helix-β-strand unit (1976) (162)
SIRIUS. An automated method for the analysis of the preferred packing arrangements between protein groups. (1990) (159)
Protein domain interfaces: characterization and comparison with oligomeric protein interfaces. (2000) (152)
PoreWalker: A Novel Tool for the Identification and Characterization of Channels in Transmembrane Proteins from Their Three-Dimensional Structure (2009) (152)
A structural biology community assessment of AlphaFold2 applications (2021) (147)
Ammonium Sensing in Escherichia coli (2004) (147)
Conformational changes observed in enzyme crystal structures upon substrate binding. (2005) (145)
Extending CATH: increasing coverage of the protein structure universe and linking structure with function (2010) (145)
Quantifying the similarities within fold space. (2002) (145)
Potential energy functions for threading. (1996) (143)
Deviations from planarity of the peptide bond in peptides and proteins. (1996) (143)
Heme proteins—Diversity in structural characteristics, function, and folding (2010) (143)
Searching for functional sites in protein structures. (2004) (141)
Integrating mutation data and structural analysis of the TP53 tumor‐suppressor protein (2002) (140)
Atlas of protein side-chain interactions (1992) (139)
Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. (2003) (138)
BLEEP—potential of mean force describing protein–ligand interactions: I. Generating potential (1999) (138)
Using a library of structural templates to recognise catalytic sites and explore their evolution in homologous families. (2005) (137)
Progress of structural genomics initiatives: an analysis of solved target structures. (2005) (136)
Small Molecule Subgraph Detector (SMSD) toolkit (2009) (134)
Elucidating Human Phosphatase-Substrate Networks (2013) (133)
Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis (2016) (133)
Sequence and structural differences between enzyme and nonenzyme homologs. (2002) (133)
Prediction of the location and type of β‐turns in proteins using neural networks (1999) (132)
Protein fold recognition (1993) (129)
Alpha plus beta folds revisited: some favoured motifs. (1993) (128)
Evolution of protein function, from a structural perspective. (1999) (125)
Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans (2006) (125)
On the conformation of proteins: the handedness of the connection between parallel beta-strands. (1977) (124)
DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO (2010) (122)
The CCPN project: an interim report on a data model for the NMR community (2002) (122)
Understanding the functional roles of amino acid residues in enzyme catalysis. (2009) (121)
Analysis and prediction of carbohydrate binding sites. (2000) (120)
Recognition of super-secondary structure in proteins. (1984) (120)
Assessment of conformational parameters as predictors of limited proteolytic sites in native protein structures. (1998) (119)
Protein structural topology: Automated analysis and diagrammatic representation (2008) (118)
Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice. (2006) (117)
The evolution and structural anatomy of the small molecule metabolic pathways in Escherichia coli. (2001) (116)
Protein recognition of adenylate: an example of a fuzzy recognition template. (1996) (115)
Identifying DNA-binding proteins using structural motifs and the electrostatic potential. (2004) (112)
Protein Superfamily Evolution and the Last Universal Common Ancestor (LUCA) (2006) (112)
Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling (2011) (110)
Protein domain superfolds and superfamilies (1994) (110)
Prediction of super-secondary structure in proteins (1983) (109)
Structures of N‐termini of helices in proteins (1997) (109)
Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage. (1998) (109)
EC-BLAST: A Tool to Automatically Search and Compare Enzyme Reactions (2014) (109)
The European Bioinformatics Institute's data resources: towards systems biology (2004) (109)
Wavelet transforms for the characterization and detection of repeating motifs. (2002) (109)
Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites (2017) (107)
Analysis and prediction of the different types of beta-turn in proteins. (1988) (107)
Who checks the checkers? Four validation tools applied to eight atomic resolution structures. EU 3-D Validation Network. (1998) (107)
Molecular basis of inherited diseases: a structural perspective. (2003) (106)
Detection of 3D atomic similarities and their use in the discrimination of small molecule protein-binding sites (2008) (106)
Motif-based searching in TOPS protein topology databases (1999) (106)
Assessment of comparative modeling in CASP2 (1997) (106)
CATH: expanding the horizons of structure-based functional annotations for genome sequences (2018) (106)
The European Bioinformatics Institute’s data resources (2009) (106)
Sequences annotated by structure: a tool to facilitate the use of structural information in sequence analysis. (1998) (105)
A structure-based anatomy of the E.coli metabolome. (2003) (104)
Prediction of protein structure from amino acid sequence (1978) (104)
RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. (2002) (103)
Conformational diversity of ligands bound to proteins. (2006) (102)
Evolution of protein superfamilies and bacterial genome size. (2004) (101)
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease (2017) (99)
Integrating Structure, Bioinformatics, and Enzymology to Discover Function (2003) (99)
From protein structure to biochemical function? (2004) (99)
The CATH protein family database: A resource for structural and functional annotation of genomes (2002) (99)
Comparison of functional annotation schemes for genomes (2000) (99)
An ellipsoidal approximation of protein shape (1983) (98)
Erratum: Corrigendum: The European dimension for the mouse genome mutagenesis program (2004) (95)
Longevity GWAS Using the Drosophila Genetic Reference Panel (2015) (95)
Three-dimensional structure analysis of PROSITE patterns. (1999) (94)
Recognizing the fold of a protein structure (2003) (94)
Successful protein fold recognition by optimal sequence threading validated by rigorous blind testing (1995) (94)
HERA—A program to draw schematic diagrams of protein secondary structures (1990) (93)
Automatic inference of protein quaternary structure from crystals (2003) (91)
From Genome to Function (2001) (91)
Prediction of strand pairing in antiparallel and parallel β‐sheets using information theory (2002) (90)
Catalysing new reactions during evolution: economy of residues and mechanism. (2003) (89)
The CATH domain structure database. (2005) (89)
The Classification and Evolution of Enzyme Function. (2015) (89)
Towards an understanding of the arginine-aspartate interaction. (1992) (89)
An algorithm for automatically generating protein topology cartoons. (1994) (88)
Pathway evolution, structurally speaking. (2002) (85)
ELIXIR: a distributed infrastructure for European biological data. (2012) (85)
Retrograde Response to Mitochondrial Dysfunction Is Separable from TOR1/2 Regulation of Retrograde Gene Expression* (2005) (85)
Beta-hairpin families in globular proteins. (1985) (84)
Regulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk (2010) (84)
Minimum information about a bioactive entity (MIABE) (2011) (84)
Conformational change in substrate binding, catalysis and product release: an open and shut case? (2004) (83)
Protein fold recognition by sequence threading: tools and assessment techniques (1996) (83)
Ligand selectivity and competition between enzymes in silico (2004) (82)
The Greek key motif: extraction, classification and analysis. (1993) (82)
Correlation of observed fold frequency with the occurrence of local structural motifs. (1999) (81)
X-SITE: use of empirically derived atomic packing preferences to identify favourable interaction regions in the binding sites of proteins. (1996) (81)
Morphological aspects of oligomeric protein structures. (2005) (81)
Knowledge-based validation of protein structure coordinates derived by X-ray crystallography and NMR spectroscopy (1994) (81)
Towards fully automated structure-based function prediction in structural genomics: a case study. (2007) (80)
On the molecular discrimination between adenine and guanine by proteins. (2001) (80)
Exploring the Evolution of Novel Enzyme Functions within Structurally Defined Protein Superfamilies (2012) (79)
Gene3D: structural assignment for whole genes and genomes using the CATH domain structure database. (2002) (79)
[5] Conformation of β hairpins in protein structures: Classification and diversity in homologous structures (1991) (78)
A bioinformatician's view of the metabolome. (2006) (78)
Calcium binding by troponin-C. A proton magnetic resonance study. (1977) (78)
Analysis of domain structural class using an automated class assignment protocol. (1996) (75)
Barrel structures in proteins: Automatic identification and classification including a sequence analysis of TIM barrels (1999) (74)
Rebuilding flavodoxin from Cα coordinates: A test study (1989) (74)
Bioinformatics: Genes, Proteins and Computers (2007) (73)
Control of AmtB-GlnK Complex Formation by Intracellular Levels of ATP, ADP, and 2-Oxoglutarate* (2010) (71)
MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms (2006) (71)
Reaction Decoder Tool (RDT): extracting features from chemical reactions (2016) (70)
BLEEP - potential of mean force describing protein-ligand interactions: I. Generating potential (1999) (70)
Prediction of progress at last (1991) (70)
Activation of the SPS Amino Acid-Sensing Pathway in Saccharomyces cerevisiae Correlates with the Phosphorylation State of a Sensor Component, Ptr3 (2007) (69)
Effective function annotation through catalytic residue conservation. (2005) (68)
Understanding the molecular machinery of genetics through 3D structures (2008) (68)
The CATH Dictionary of Homologous Superfamilies (DHS): a consensus approach for identifying distant structural homologues. (2000) (66)
A rapid classification protocol for the CATH Domain Database to support structural genomics (2001) (66)
An atlas of protein topology cartoons available on the World-Wide Web. (1998) (66)
Structural and sequence patterns in the loops of βαβ units (1987) (66)
Functional and modelling studies of the binding of human monoclonal anti-DNA antibodies to DNA. (1996) (65)
Homology, pathway distance and chromosomal localization of the small molecule metabolism enzymes in Escherichia coli. (2002) (65)
Microeconomic Principles Explain an Optimal Genome Size in Bacteria (2004) (64)
Conformational analysis of protein structures derived from NMR data (1993) (64)
Small-molecule metabolism: an enzyme mosaic. (2001) (63)
Using structural motif templates to identify proteins with DNA binding function. (2003) (63)
Metal-MACiE: a database of metals involved in biological catalysis (2009) (63)
On the conformation of proteins: an analysis of β-pleated sheets (1977) (63)
PDBe-KB: a community-driven resource for structural and functional annotations (2019) (63)
Evolution of enzymes and pathways for the biosynthesis of cofactors. (2007) (62)
Protein motifs and data-base searching. (1989) (62)
Molecular docking for substrate identification: the short-chain dehydrogenases/reductases. (2008) (62)
A study into the effects of protein binding on nucleotide conformation. (1993) (61)
Modelling protein unfolding: hen egg-white lysozyme. (1997) (61)
Chopping and Changing: the Evolution of the Flavin-dependent Monooxygenases (2016) (60)
BLEEP—potential of mean force describing protein–ligand interactions: II. Calculation of binding energies and comparison with experimental data (1999) (60)
DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans (2014) (59)
Missing in action: enzyme functional annotations in biological databases. (2009) (59)
On the conformation of proteins: hydrophobic ordering of strands in beta-pleated sheets. (1977) (59)
AlphaFold heralds a data-driven revolution in biology and medicine (2021) (59)
Emerging concepts in pseudoenzyme classification, evolution, and signaling (2019) (59)
The metastasis-promoting phosphatase PRL-3 shows activity toward phosphoinositides. (2011) (59)
Analysis of protein main-chain solvation as a function of secondary structure. (1991) (58)
BLEEP - potential of mean force describing protein-ligand interactions: II. Calculation of binding energies and comparison with experimental data (1999) (58)
Accommodating sequence changes in β-hairpins in proteins (1993) (57)
The CATH Hierarchy Revisited—Structural Divergence in Domain Superfamilies and the Continuity of Fold Space (2009) (57)
VarSite: Disease variants and protein structure (2019) (56)
The application of hydrogen bonding analysis in X-ray crystallography to help orientate asparagine, glutamine and histidine side chains. (1995) (56)
Recurring structural motifs in proteins with different functions (1993) (56)
On the diversity of physicochemical environments experienced by identical ligands in binding pockets of unrelated proteins (2010) (55)
Genome and proteome annotation: organization, interpretation and integration (2009) (54)
The structures and physicochemical properties of organic cofactors in biocatalysis. (2010) (54)
Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1 (2019) (54)
Dihydrofolate reductase: A potential drug target in trypanosomes and leishmania (1998) (53)
Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1). (1998) (53)
Amino Acid Changes in Disease-Associated Variants Differ Radically from Variants Observed in the 1000 Genomes Project Dataset (2013) (53)
Structural analysis of metal sites in proteins: non-heme iron sites as a case study. (2009) (51)
The impact of AlphaFold2 one year on (2022) (50)
Gene expression‐based drug repurposing to target aging (2018) (50)
Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies (2016) (50)
Contemporary approaches to protein structure classification (1998) (49)
Quantitative determination of the conformation of ATP in aqueous solution using the lanthanide cations as nuclear-magnetic-resonance probes. (1975) (49)
The European Bioinformatics Institute’s data resources 2014 (2013) (49)
Intrinsic phi, psi propensities of amino acids, derived from the coil regions of known structures. (1995) (48)
Evolutionary Models for Formation of Network Motifs and Modularity in the Saccharomyces Transcription Factor Network (2007) (48)
MACiE: a database of enzyme reaction mechanisms (2005) (47)
Electrostatics of aquaporin and aquaglyceroporin channels correlates with their transport selectivity (2010) (47)
Topological and stereochemical restrictions in β-sandwich protein structures (1993) (47)
The (βα)8 glycosidases: sequence and structure analyses suggest distant evolutionary relationships (2001) (45)
Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity (2015) (45)
The CoFactor database: organic cofactors in enzyme catalysis (2010) (45)
Inferring protein function from structure. (2003) (45)
A novel degron-mediated degradation of the RTG pathway regulator, Mks1p, by SCFGrr1. (2005) (45)
Relationship between the tissue-specificity of mouse gene expression and the evolutionary origin and function of the proteins (2005) (44)
To what extent do structural changes in catalytic metal sites affect enzyme function? (2018) (44)
Computational analysis of alpha-helical membrane protein structure: implications for the prediction of 3D structural models. (2004) (44)
Toward the detection and validation of repeats in protein structure (2004) (44)
PII signal transduction proteins are ATPases whose activity is regulated by 2-oxoglutarate (2013) (44)
FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies (2011) (43)
Toward predicting protein topology: An approach to identifying β hairpins (2002) (42)
Analysis of binding site similarity, small-molecule similarity and experimental binding profiles in the human cytosolic sulfotransferase family (2007) (41)
Amino/aromatic interactions (1993) (41)
PROCOGNATE: a cognate ligand domain mapping for enzymes (2007) (41)
1H NMR structure of an antifungal γ‐thionin protein SIα1: Similarity to scorpion toxins (1998) (41)
Electrostatic interactions in proteins (1982) (41)
Evolution of binding sites for zinc and calcium ions playing structural roles (2008) (41)
Erratum to “Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans” [Mech. Ageing Dev. 127 (5) (2006) 458–472] (2006) (41)
The chemistry of protein catalysis. (2007) (40)
Adenosine Triphosphate (ATP) Is a Candidate Signaling Molecule in the Mitochondria-to-Nucleus Retrograde Response Pathway (2013) (40)
SCOPEC: a database of protein catalytic domains (2004) (40)
The complement of enzymatic sets in different species. (2005) (39)
Long loops in proteins. (1995) (39)
Computational biology for ageing (2011) (39)
A global analysis of function and conservation of catalytic residues in enzymes (2019) (38)
Molecular basis for DPY-30 association to COMPASS-like and NURF complexes. (2014) (38)
TORC2 Signaling Is Antagonized by Protein Phosphatase 2A and the Far Complex in Saccharomyces cerevisiae (2012) (37)
Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity (2017) (37)
Classifying a protein in the CATH database of domain structures. (1998) (36)
Understanding enzyme function evolution from a computational perspective. (2017) (36)
Comparison of the calcium- and magnesium-induced structural changes of troponin--C. A proton magnetic resonance study. (1978) (36)
Characterizing the complexity of enzymes on the basis of their mechanisms and structures with a bio-computational analysis (2011) (36)
Structural genomics takes off. (2001) (35)
A Computer System to Perform Structure Comparison using Representations of Protein Structure (2001) (35)
A nuclear magnetic resonance investigation of the conformation of nicotinamide mononucleotide in aqueous solution. (1975) (34)
HTHquery: a method for detecting DNA-binding proteins with a helix-turn-helix structural motif (2005) (34)
A novel approach to the recognition of protein architecture from sequence using fourier analysis and neural networks (2002) (34)
An analysis of the three-dimensional structure of chicken triose phosphate isomerase. (1977) (34)
Prediction of protein function from structure: insights from methods for the detection of local structural similarities. (2005) (34)
Towards meeting the paracelsus challenge: The design, synthesis, and characterization of paracelsin‐43, an α‐helical protein with over 50% sequence identity to an all‐β protein (1996) (34)
NMR and crystallography--complementary approaches to structure determination. (1994) (34)
The new science of ageing (2011) (32)
Non‐randomness in side‐chain packing: the distribution of interplanar angles (1997) (31)
Conformation of beta hairpins in protein structures: classification and diversity in homologous structures. (1991) (31)
Using the drug-protein interactome to identify anti-ageing compounds for humans (2018) (30)
Analysing variation in Drosophila aging across independent experimental studies: a meta-analysis of survival data (2013) (30)
Atomic environments of arginine side chains in proteins. (1993) (30)
Target Selection and Determination of Function in Structural Genomics (2003) (29)
A ligand-centric analysis of the diversity and evolution of protein-ligand relationships in E.coli. (2005) (29)
The Protein Feature Ontology: a tool for the unification of protein feature annotations (2008) (29)
Drug repurposing for aging research using model organisms (2017) (29)
An analysis of the structure of triose phosphate isomerase and its comparison with lactate dehydrogenase. (1978) (29)
The history of the CATH structural classification of protein domains (2015) (28)
Solvent-induced distortions and the curvature of alpha-helices. (1983) (28)
Ferrets (Mustela putoius furo) Inefficiently Convert β-Carotene to Vitamin A (1998) (28)
Temporal changes in the gene expression heterogeneity during brain development and aging (2020) (28)
The evolution of enzyme function in the isomerases (2014) (28)
VarMap: a web tool for mapping genomic coordinates to protein sequence and structure and retrieving protein structural annotations (2019) (28)
Structural analysis of pathogenic mutations in the DYRK1A gene in patients with developmental disorders (2017) (28)
Protein folds: towards understanding folding from inspection of native structures. (1995) (28)
Amino acid sequence templates derived from recurrent turn motifs in proteins: critical evaluation of their predictive power. (1989) (28)
Protein side-chain conformation: a systematic variation of chi 1 mean values with resolution - a consequence of multiple rotameric states? (1999) (28)
Multiple solution conformations of the integrin-binding cyclic pentapeptide cyclo(-Ser-D-Leu-Asp-Val-Pro-). Analysis of the (phi, psi) space available to cyclic pentapeptides. (1996) (27)
Correcting for sequence biases in present/absent calls (2007) (27)
The Escherichia coli AmtB protein as a model system for understanding ammonium transport by Amt and Rh proteins. (2006) (27)
Relating tissue specialization to the differentiation of expression of singleton and duplicate mouse proteins (2006) (27)
Protein structure and phenotypic analysis of pathogenic and population missense variants in STXBP1 (2017) (27)
Gene3D: structural assignments for the biologist and bioinformaticist alike (2003) (27)
Depicting topology and handedness in jellyroll structures (1992) (26)
Design, synthesis and structure of a zinc finger with an artificial beta-turn. (1998) (26)
Factors limiting the performance of prediction‐based fold recognition methods (2008) (26)
Cognate ligand domain mapping for enzymes. (2006) (25)
Structural similarity between the pleckstrin homology domain and verotoxin: The problem of measuring and evaluating structural similarity (1995) (24)
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila (2020) (24)
Evaluation of a knowledge‐based potential of mean force for scoring docked protein–ligand complexes (2001) (24)
MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans (2014) (24)
Protein structure prediction. (1998) (24)
Using the CATH domain database to assign structures and functions to the genome sequences. (2000) (24)
Functional conservation in genes and pathways linking ageing and immunity (2021) (23)
Influence of secondary structure on the hydration of serine, threonine and tyrosine residues in proteins. (1990) (23)
Recurrence of a binding motif? (1993) (23)
Software engineering challenges in bioinformatics (2004) (23)
Detecting DNA-binding helix–turn–helix structural motifs using sequence and structure information (2005) (22)
PDBe-KB: collaboratively defining the biological context of structural data (2021) (22)
Integrating population variation and protein structural analysis to improve clinical interpretation of missense variation: application to the WD40 domain (2016) (22)
Detection of 3 D atomic similarities and their use in the discrimination of small molecule protein-binding sites (2008) (22)
Unlocking the potential of survival data for model organisms through a new database and online analysis platform: SurvCurv (2013) (21)
Common genetic associations between age-related diseases (2020) (21)
A comparison of three theoretical approaches to the study of side-chain interactions in proteins (1993) (21)
The ammonia channel protein AmtB from Escherichia coli is a polytopic membrane protein with a cleavable signal peptide. (2006) (21)
New tools and resources for analysing protein structures and their interactions. (1998) (21)
Protein-protein recognition via side-chain interactions. (1988) (20)
The (non)malignancy of cancerous amino acidic substitutions (2010) (20)
Lessons from analyzing protein structures (1992) (20)
A study of structural determinants in the interleukin-1 fold. (1993) (20)
SPINE bioinformatics and data‐management aspects of high‐throughput structural biology (2006) (20)
Solution structure of a biologically active cyclic LDV peptide analogue containing a type II' beta-turn mimetic. (2009) (19)
A novel method for the modelling of peptide ligands to their receptors. (1991) (19)
On the conformation of proteins: the handedness of the beta-strand-alpha-helix-beta-strand unit. (1976) (19)
On the conformation of proteins: towards the prediction of strand arrangements in beta-pleated sheets. (1977) (19)
PDBsum extras: SARS‐CoV‐2 and AlphaFold models (2021) (18)
Metabolic innovations towards the human lineage (2008) (18)
WSsas: a web service for the annotation of functional residues through structural homologues (2009) (18)
The widespread increase in inter-individual variability of gene expression in the human brain with age (2019) (18)
The influence of tertiary structure on secondary structure prediction (1985) (18)
The EBI enzyme portal (2012) (18)
Conformation of terminal regions in proteins (1982) (18)
Molecular modelling and epitope prediction of gp29 from lymphatic filariae. (1993) (18)
An analysis of intron positions in relation to nucleotides, amino acids, and protein secondary structure. (2006) (17)
A template search reveals mechanistic similarities and differences in β‐ketoacyl synthases (KAS) and related enzymes (2003) (17)
Comparison of the mammalian insulin signalling pathway to invertebrates in the context of FOXO-mediated ageing (2014) (17)
Amino acid architecture and the distribution of polar atoms on the surfaces of proteins (2005) (17)
Exploring the chemistry and evolution of the isomerases (2016) (17)
Modelling by homology (1991) (17)
The BC loop in poliovirus coat protein VP1: an ideal acceptor site for major insertions. (1994) (16)
Current challenges in genome annotation through structural biology and bioinformatics. (2012) (16)
Correction: Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases (2007) (16)
Analysis of metabolic networks using a pathway distance metric through linear programming. (2003) (16)
Estimation and correction of non-specific binding in a large-scale spike-in experiment (2007) (16)
Sequences and topology. (2001) (15)
THE RAMACHANDRAN PLOT AND PROTEIN STRUCTURE VALIDATION (2013) (15)
Topology-based protein structure comparison using a pattern discovery technique (2000) (15)
Annotations for all by all - the BioSapiens network (2009) (15)
Protein structures and complexes: what they reveal about the interactions that stabilize them (1993) (15)
A practical and robust sequence search strategy for structural genomics target selection (2004) (15)
Mapping Human Metabolic Pathways in the Small Molecule Chemical Space (2009) (15)
Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing (2012) (15)
Peptide–protein interactions: an overview (1993) (15)
Three-dimensional structural aspects of the design of new protein molecules (1986) (14)
Conformational energy calculations for dinucleotide molecules. A study of the component mononucleotide adenosine 3'-monophosphate. (1975) (14)
Conformational studies of lanthanide complexes with carboxylate ligands (1974) (14)
Integrating biological data through the genome. (2006) (14)
The (betaalpha)(8) glycosidases: sequence and structure analyses suggest distant evolutionary relationships. (2001) (14)
Characterising Complex Enzyme Reaction Data (2015) (14)
Exploring Chemical Biosynthetic Design Space with Transform-MinER. (2019) (14)
1,000 structures and more from the MCSG (2011) (13)
SurvCurv database and online survival analysis platform update (2015) (13)
An extension of secondary structure prediction towards the production of tertiary structure (1991) (13)
Macromolecular structure information and databases (1996) (13)
Identifying Potential Ageing-Modulating Drugs In Silico (2019) (13)
The Hans Neurath Award lecture of The Protein Society: Proteins—A testament to physics, chemistry, and evolution (2001) (13)
Substrate recognition by proteinases. (1992) (13)
Accommodating sequence changes in beta-hairpins in proteins. (1993) (13)
Structures in the AKH Family of Neuropeptides (1990) (12)
Smith, G.P. et al. Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage. J. Mol. Biol. 277, 317-332 (1998) (12)
Toward predicting protein topology: an approach to identifying beta hairpins. (2002) (12)
The geometry of interactions between catalytic residues and their substrates. (2007) (12)
Proton magnetic resonance study of troponin‐C (1976) (12)
Protein–DNA Interactions: The Story so Far and a New Method for Prediction (2003) (12)
Editorial overviewSequences and topology (2003) (12)
Structural and sequence patterns in the loops of beta alpha beta units. (1987) (11)
PoreLogo: a new tool to analyse, visualize and compare channels in transmembrane proteins (2009) (11)
Exploring the Biological and Chemical Complexity of the Ligases (2014) (11)
Ranking Enzyme Structures in the PDB by Bound Ligand Similarity to Biological Substrates (2018) (11)
Finding enzyme cofactors in Protein Data Bank (2019) (11)
Identifying pseudoenzymes using functional annotation: pitfalls of common practice (2020) (11)
Data-driven identification of ageing-related diseases from electronic health records (2021) (11)
Methods to characterize the structure of enzyme binding sites (2008) (11)
Structural survey (1987) (10)
Modelling protein unfolding: A solvent insertion protocol (1996) (10)
DOMPLOT: a program to generate schematic diagrams of the structural domain organization within proteins, annotated by ligand contacts. (1999) (10)
Molecular recognition by proteins: protein-ligand interactions from a structural perspective. (1996) (10)
Association and dissociation of the GlnK–AmtB complex in response to cellular nitrogen status can occur in the absence of GlnK post-translational modification (2014) (9)
A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) (2020) (9)
Transform-MinER: transforming molecules in enzyme reactions (2018) (9)
Living longer by dieting: analysis of transcriptional response after caloric restriction (2005) (9)
Towards meeting the Paracelsus Challenge: The design, synthesis, and characterization of paracelsin-43, an alpha-helical protein with over 50% sequence identity to an all-beta protein. (1996) (9)
Delivering ICT infrastructure for biomedical research (2012) (8)
Iditis: protein structure database. (1998) (8)
Rebuilding flavodoxin from C alpha coordinates: a test study. (1989) (8)
Abstracting knowledge from the Protein Data Bank. (2013) (8)
cuRRBS: simple and robust evaluation of enzyme combinations for reduced representation approaches (2017) (8)
The future of bioinformatics (1998) (8)
The shape of things to come? (1988) (7)
Topological and stereochemical restrictions in beta-sandwich protein structures. (1993) (7)
Protein folds and their recognition from sequence (1996) (7)
Exploring Enzyme Evolution from Changes in Sequence, Structure, and Function. (2018) (7)
Interactive map projection algorithm for illustrating protein surfaces (1986) (7)
The structures of some cobalamins in solution. (1976) (7)
Variation of geometrical and physicochemical properties in protein binding pockets and their ligands (2007) (7)
EuroQSAR 2002: Designing Drugs and Crop Protectants: processes, problems and solution (2003) (7)
Prediction of protein structure from amino acid sequence. (1978) (7)
Structure‐Based Prediction of Enzymes and Their Active Sites (2008) (6)
Structure prediction and modelling. (1991) (6)
Tackling a loopy problem (1990) (6)
On the conformation of proteins: an analysis of beta-pleated sheets. (1977) (6)
Ferrets (Mustela putoius furo) inefficiently convert beta-carotene to vitamin A. (1998) (6)
Conformational energy calculations for dinucleotide molecules. A systematic study of dinucleotide conformation, with application to diadenosine pyrophosphate (1976) (6)
Conformational energy calculations for dinucleotide molecules: A study of the nucleotide coenzyme nicotinamide adenine dinucleotide (NAD+) (1977) (6)
Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice (2020) (6)
Structural analysis of pathogenic missense mutations in GABRA2 and identification of a novel de novo variant in the desensitization gate (2019) (5)
Data Curation in Biology – Past, Present and Future (2009) (5)
Introduction. Bioinformatics: from molecules to systems (2006) (5)
Domain–ligand mapping for enzymes (2009) (5)
Programs and program systems in wide use (2006) (5)
Mapping Circular Current for a Single Brain Cancer Cell ’ s Spatial-Temporal Orientations Based on a Memristor / Memcapacitor (2014) (5)
Preliminary Analysis of Water Molecule Distributions in Proteins (1989) (5)
Revised 11 / 27 / 01 RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS 1 and is linked to the formation of the yeast prion [ URE 3 ] (2002) (5)
What you need to know to make the most of big data in biology (2015) (4)
An automated protocol for modelling peptide substrates to proteases (2020) (4)
Mutational analysis of GlnB residues critical for NifA activation in Azospirillum brasilense. (2015) (4)
An extension of secondary structure prediction towards the prediction of tertiary structure (2001) (4)
In conversation with Janet Thornton (2020) (4)
Protein structure. Prediction of progress at last. (1991) (4)
Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system (2021) (4)
Nanostructured Memristor Sensor Mimics Acetylcholinesterase (ACHE) Active Sites in the Gorge for fM Detection of Acetylcholine (2014) (4)
Morphological aspects of oligorneric protein structures (2005) (4)
Transposable Element Landscape in Drosophila Populations Selected for Longevity (2019) (4)
Nutrient Requirements and Interactions Ferrets ( Mustela putoius furo ) Inefficiently Convert b-Carotene to Vitamin A 1 (1998) (4)
Conformational Variation in Enzyme Catalysis: A Structural Study on Catalytic Residues (2021) (4)
GRaSP: a graph-based residue neighborhood strategy to predict binding sites. (2020) (4)
Transcriptional feedback in the insulin signalling pathway modulates ageing in both Caenorhabditis elegans and Drosophila melanogaster † †Electronic supplementary information (ESI) available. See DOI: 10.1039/c3mb25485b Click here for additional data file. (2013) (4)
Discovering of Collagen-1’s Role in Producing Superconducting Current in Nanobiomimetic Superlattice Structured Organometallic Devices at Room Temperature Enabled Direct Quantitation of Sub pg/mL Collagen-1 by a Voltage and a Cyclic Voltammetry Method (2018) (3)
Coordination of structural bioinformatics activities across Europe (2018) (3)
Identifying pseudoenzymes using functional annotation. How loss of function correlates with mutations in the catalytic site. (2019) (3)
Analysis and prediction of membrane protein structure (2004) (3)
Classifying a Protein Fold in the CATH Hierarchic Database (1998) (3)
Protein Evolution: Sequences, Structures and Systems (2009) (3)
Impact of Structural Observables From Simulations to Predict the Effect of Single-Point Mutations in MHC Class II Peptide Binders (2021) (3)
Shared structural motif in proteins (1993) (3)
The fine details of evolution. (2009) (3)
An examination of the conservation of surface patch polarity for proteins (2004) (3)
Nanostructured Acetylcholinesterase (ACHE) Memristor/Memcapacitor Mimicks Brachyhypopomus Electric Fish’s Signal-Cloaking Behavior (2014) (3)
Modelling antibody combining sites: a review. (2007) (3)
Gene Expression-Based Drug Repurposing to Target Ageing (2018) (3)
A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases (2021) (3)
Protein promiscuity and its implications for (2009) (3)
Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity (2021) (3)
Nanostructured Biomimetic Memristor Sensors Used for Therapeutic Monitoring of the Brain Cancer (2014) (2)
Protein Quaternary Structure: Subunit–Subunit Interactions (2001) (2)
Case Studies: Function Predictions of Structural Genomics Results (2009) (2)
Binding pocket shape analysis for protein function prediction (2005) (2)
Proteins: interaction at a distance (2015) (2)
Macromolecular structure information and databases. The EU BRIDGE Database Project Consortium. (1996) (2)
Prediction of protein structure from amino acid sequence. (1981) (2)
The variability of expression of many genes and most functional pathways is observed to increase with age in brain transcriptome data (2019) (2)
Faculty Opinions recommendation of Structural basis for thermostability of beta-glycosidase from the thermophilic eubacterium Thermus nonproteolyticus HG102. (2003) (2)
Protein Data Resources (2013) (2)
Corrigendum to “Progress of Structural Genomics Initiatives: An Analysis of Solved Target Structures” [J. Mol. Biol. (2005) 348, 1235–1260] (2005) (2)
Protein-DNA Interactions (1999) (2)
A Nanobiomimetic Neuronal Memcapacitor Serves as a Voltage Sensor and an Amperometry Sensor for Reagent-less Direct Detection of Sub pM Soluble Amyloid-beta (2015) (2)
Using mechanism similarity to understand enzyme evolution (2022) (2)
LigSearch: a knowledge-based web server to identify likely ligands for a protein target (2013) (2)
Secondary and Supersecondary Motifs in Protein Structures (1992) (2)
Selectivity study for a reagent-less and enzyme-free nanopore glucose sensor against interferences of non-glucose sugars and other substances (2011) (2)
Use of a Pathway Distance Metric through Linear Programming for the Analysis of Metabolic Networks. (2002) (1)
New open drug activity data at EBI (2009) (1)
Progress towards recognising protein folds from amino acid sequence (1993) (1)
Building and design (1987) (1)
TORC2 Signaling is Antagonized by Protein Phosphatase 2A and the Far Complex in S. cerevisiae (2012) (1)
Protein Function Prediction from Structure in Structural Genomics and its Contribution to the Study of Health and Disease (2009) (1)
Gene expression heterogeneity during brain development and aging: temporal changes and functional consequences (2019) (1)
Structural Patterns in Globular Proteins (1994) (1)
Lithium Promotes Longevi ty through GSK 3 / NRF 2-Dependent Hormesis Graphical (2016) (1)
A Nanopore Biomimetic Device Quantitatively Detects Early Stage Cancer Cells; a Contour Map Multiple Variable Correlation Method Assesses the Heat of Cancer Cells Released (2012) (1)
Acetylcholine Repairs the Amyloid-beta Damage on Brain Circuitry and Memory Loss From a “Mutated Biomimetic Acetylcholinesterase” Neuronal Memcapacitor During Slow-Wave Sleeping (2015) (1)
Nanobiomimetic Memristor/Memcapacitor Devices Used for Direct and Reagent-less Detection of Sub pM Acetyl Coenzyme A in Milks (2016) (1)
THE EVOLUTION OF ENZYME STRUCTURE AND FUNCTION (2000) (1)
The Enzyme Portal: an integrative tool for enzyme information and analysis (2021) (1)
Capturing the geometry, function, and evolution of enzymes with 3D templates (2022) (1)
Drug repurposing for ageing research using model organisms (2016) (1)
GRaSP-web: a machine learning strategy to predict binding sites based on residue neighborhood graphs (2022) (1)
Meta-Analysis of the Gene Expression Profiles of Aging Brain Reveals Consistent Increase in Heterogeneity (2019) (1)
Protein Function Prediction by Matching Volumetric Models of Active Sites (2006) (1)
Flexible and Turnable Biomimetic Pyruvate Dehydrogenase Complex (PDC) Supercapacitors (2013) (1)
Evolution of Enzymes and Pathways for the Biosynthesis of Cofactors (2008) (1)
WHAT CAN COMPARATIVE GENOMICS REVEAL ABOUT THE MECHANISMS OF PROTEIN FUNCTION EVOLUTION (2014) (1)
Protein domain assignments (1999) (1)
Modelling the interactions of protein side-chains (1995) (1)
Insights into protein evolution and function from the CATH structural database (2001) (1)
MG_HW2: Downloading SRA data using the SRA toolkit (2016) (1)
Srinivasan (1962–2021) in Bioinformatics and beyond (2022) (1)
Shape-based classification of bound ligands (1)
EzMechanism: An Automated Tool to Propose Catalytic Mechanisms of Enzyme Reactions (2022) (1)
The Advantages of Human Milk Recognize the Spatiotemporal Locations of Toxins and Intelligently Bypass Them by Forming a Hummingbird-Like Hovering Neural Network Circuitry Based on an Organic Biomimetic Choline Acetyltransferase Memristor / Memcapacitor Prosthesis (2016) (0)
Evolution of NAD (P)H binding domain superfamily (2012) (0)
MG_HW5: Mapping reads with Bowtie2 (2016) (0)
Protein‐fold classification (2012) (0)
Faculty Opinions recommendation of Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family. (2002) (0)
Faculty Opinions recommendation of A simple physical model for the prediction and design of protein-DNA interactions. (2004) (0)
Faculty Opinions recommendation of Identification and analysis of catalytic TIM barrel domains in seven further glycoside hydrolase families. (2003) (0)
Faculty Opinions recommendation of GeneCensus: genome comparisons in terms of metabolic pathway activity and protein family sharing. (2002) (0)
Faculty Opinions recommendation of Conservation of electrostatic properties within enzyme families and superfamilies. (2003) (0)
DECONVOLUTING THE DEMENTIA PHENOTYPE USING FUNCTIONAL COMPUTATIONAL APPROACHES (2018) (0)
Analysis and modelling of antibodies. (1995) (0)
Faculty Opinions recommendation of Moment-based prediction of DNA-binding proteins. (2004) (0)
PROTEIN NUCLEIC ACID INTERACTIONS GRANT # DE-FG02-96ER62166 FINAL REPORT (2005) (0)
Chapter 4 – Molecular Sociology (2003) (0)
Faculty Opinions recommendation of Making sense of the diverse ligand recognition by NKG2D. (2003) (0)
Faculty Opinions recommendation of Enzyme family classification by support vector machines. (2004) (0)
Editorial overviewProtein engineering (1995) (0)
Proceedings Twelfth International Conference on Intelligent Systems for Molecular Biology/Third European Conference on Computional Biology 2004 (ISMB/ECCB 2004) (2004) (0)
Editorial overview: Catalysis and regulation. (2017) (0)
Using the Mechanism and Catalytic Site Atlas (M-CSA) to understand enzyme function and evolution (2017) (0)
Antibody modelling. Tackling a loopy problem. (1990) (0)
The applications of computer calligraphics in protein engineering and drug design (1984) (0)
Shouldn't enantiomeric purity be included in the 'minimum information about a bioactive entity? Response from the MIABE group (2012) (0)
Some principles of protein structure (1981) (0)
2 . 2 Identifying catalytic domains in the PDB (2004) (0)
AlphaFold2 protein structure prediction: Implications for drug discovery. (2023) (0)
Faculty Opinions recommendation of An orientation-dependent hydrogen bonding potential improves prediction of specificity and structure for proteins and protein-protein complexes. (2003) (0)
Proteomics: The protein complement of the genome (2003) (0)
NEW CARBOXYLESTERASE FROM ESCHERICHIA COLI * (2003) (0)
[Invited Lecture] Protein Folds and Functions (1998) (0)
Drug binding to the hERG K + channel : a molecular modelling study (2005) (0)
Mapping the Constrained Coding Regions in the Human Genome to Their Corresponding Proteins (2022) (0)
Automated analysis of enzyme reaction mechanisms (2011) (0)
The Evolution of Enzyme Mechanisms and Functional Diversity (2015) (0)
The European Bioinformatics Institute: Leading the bioinformatics revolution (2004) (0)
Faculty Opinions recommendation of Sputnik: a database platform for comparative plant genomics. (2003) (0)
The new science of ageing (2015) (0)
Faculty Opinions recommendation of Definition of the tempo of sequence diversity across an alignment and automatic identification of sequence motifs: Application to protein homologous families and superfamilies. (2003) (0)
Faculty Opinions recommendation of Convergent evolution of enzyme active sites is not a rare phenomenon. (2008) (0)
ISMB/ECCB 2004 Organization (2004) (0)
STRUCTURAL-ANALYSIS OF AN IGG HUMAN ANTI-DNA ANTIBODY - BINDING TO Z-DNA (1995) (0)
Faculty Opinions recommendation of Apollo: a sequence annotation editor. (2003) (0)
Faculty Opinions recommendation of Computational comparison of two mouse draft genomes and the human golden path. (2003) (0)
Towards automated structure-based identification of protein ligands (2007) (0)
A NUCLEAR MAGNETIC RESONANCE INVESTIGATION OF THE CONFORMATION OF NICOTINAMIDE MONONUCLEOTIDE IN AQUEOUS SOLUTION (1975) (0)
Sequences and topology Editorial overview (2003) (0)
Protein structure. The shape of things to come? (1988) (0)
Protein Engineering '87—conference report (1987) (0)
Faculty Opinions recommendation of Applications of InterPro in protein annotation and genome analysis. (2002) (0)
Protein structures: their validation fold classification and interactions (1996) (0)
Protein folds and motifs: representation, comparison and classification (2006) (0)
A public regulator of longevity acts via lineage-specific effectors. (2006) (0)
Protein motifs and folding recognition (1994) (0)
Functional Insights from Structural Families (2000) (0)
Faculty Opinions recommendation of Calmodulin target database. (2003) (0)
Annotation of organic cofactor molecules in PDB (2017) (0)
Functional conservation in genes and pathways linking ageing and immunity (2021) (0)
The proteome and the metabolome (2003) (0)
Gene expression ‐ based drug repurposing to target aging Handan (2018) (0)
Faculty Opinions recommendation of Building an automated classification of DNA-binding protein domains. (2002) (0)
Alternative Splicing in the ENCODE Protein complement (2008) (0)
Enzymes: evolution of function from a structural perspective (2002) (0)
Establishing high-throughput protein structure determination pipeline for structural genomics (2005) (0)
ELIXIR - A European Infrastructure for Biological Information: Challenges and Progress (2009) (0)
Faculty Opinions recommendation of A consensus view of fold space: combining SCOP, CATH, and the Dali Domain Dictionary. (2003) (0)
A zinc finger with an artificial beta-turn, original sequence taken from the third zinc finger domain of the human transcriptional repressor protein YY1 (YING and YANG 1, a delta transcription factor), nmr, 34 structures (1998) (0)
Faculty Opinions recommendation of Prediction of enzyme family classes. (2003) (0)
Using structural motifs to identify proteins with DNA binding function (2003) (0)
Faculty Opinions recommendation of Protein folding: could hydrophobic collapse be coupled with hydrogen-bond formation? (2003) (0)
The NAD Binding Domain and the Short‐Chain Dehydrogenase/Reductase (SDR) Superfamily (2013) (0)
An automated protocol for modelling peptide substrates to proteases (2020) (0)
Faculty Opinions recommendation of Heat capacity effects of water molecules and ions at a protein-DNA interface. (2004) (0)
Variability, Modelling and Prediction of β-Hairpins with Reference to the Immunoglobulin Fold (1985) (0)
Sequences and topology (1991) (0)
Structural and sequence patterns in the loops of ( 3 a ( 3 units (2005) (0)
Large-scale Annotation of Biochemically Relevant Pockets and Tunnels in Cognate Enzyme-Ligand Complexes (2023) (0)
Faculty Opinions recommendation of Insufficiently dehydrated hydrogen bonds as determinants of protein interactions. (2003) (0)
3 – The Analysis of Homologous Tertiary Structures and the Design of Novel Proteins (1973) (0)
Bridging cheminformatics and bioinformatics by using protein structures. (2001) (0)
A rapid algorithm for generating minimal pathway distances (2001) (0)
Faculty Opinions recommendation of Nonrandom tripeptide sequence distributions at protein carboxyl termini. (2003) (0)
Temporal changes in the gene expression heterogeneity during brain development and aging (2020) (0)
PROTEIN FOLD FAMILIES AND STRUCTURAL MOTIFS (1994) (0)
Faculty Opinions recommendation of Modulation of agrin function by alternative splicing and Ca2+ binding. (2004) (0)
A novel computational approach for predicting complex phenotypes in Drosophila (starvation-sensitive and sterile) by deriving their gene expression signatures from public data (2020) (0)
6.12 – EBI and ELIXIR (2014) (0)
Structural bioinformatics: from protein structure to function (2007) (0)
Faculty Opinions recommendation of A new hybrid approach to predict subcellular localization of proteins by incorporating gene ontology. (2004) (0)
The evolution of specificity in large protein families (2008) (0)
Faculty Opinions recommendation of Surface descriptors for protein-ligand affinity prediction. (2003) (0)
SelectBCM tool: a batch evaluation framework to select the most appropriate batch-correction methods for bulk transcriptome analysis (2023) (0)
Faculty Opinions recommendation of Atoms-in-molecules study of the genetically encoded amino acids. III. Bond and atomic properties and their correlations with experiment including mutation-induced changes in protein stability and genetic coding. (2003) (0)
A Nanopore Biomimetic Device Quantitatively Detects Early Stage Cancer Cells; a Contour Map of Multiple Variable Correlation Method Assesses the Heat Released by Cancer Cells (2012) (0)
Nanobiomimetic Memristor/memcapacitors’ Function as a Voltage Sensor for Direct and Reagent-free Detection of sub pg Lipopolysaccharide (LPS) in Milks for Children (2016) (0)
Organic Nanobiomimetic Memristor/Memcapacitor Devices Ultrasensitive Direct Detect Matrix Matelloproteinase-2 in Human Serum (2017) (0)
Nanobiomimetic Memristor/memcapacitors’ Function as a Voltage Sensor for Direct and Reagent-free Detection of sub pg Lipopolysaccharide (LPS) in Different Types of Milks for Infants (2016) (0)
NICOTINAMIDE MONONUCLEOTIDE AND ADENOSINE 3 '-MONOPHOSPHATE By (2005) (0)
The Impact of Structural Proteomics on Macromolecular Structure Databases (2008) (0)
Nanobiomimetic Structured Organo-Metal Devices Direct Rapid Real-time Monitor Atto Molarities of ATP in Biological Specimens (2019) (0)
Utilization of the Flexible Josephson Toroidal Junctions for Self- Powering 150K Super lattice Bits Having Non-volatile Memory Storage in One Device Assembly at Room Temperature (2019) (0)
Nanobiomimetic Superlattice Superconductive/Memristive Organometallic Devices at Room Temperature Serve as Chronoamperometric Sensors for sub fg/mL Collagen-1 Detection in Human Serum (2018) (0)
Software Tools for Protein Structure Analysis and Fold Classification (1999) (0)
Matching Volumetric Models of Protein Active Sites (0)
Hydration of Amino Acids in Protein Crystals (1993) (0)
Mammalian Life Span Ribosomal Protein S 6 Kinase 1 Signaling Regulates (2009) (0)
ECCB 2012 Organization (2012) (0)
Create BLAST database using CyVerse (2017) (0)
MG_HW4: Co-assembly using Megahit (2016) (0)
Fighting for the birds (2020) (0)
How to copy from host to guest machine (2016) (0)
MG_HW3: Quality Control and Pre-processing (2016) (0)
EDTA disodium salt dihydrate (2015) (0)
Relative contribution of the internal rotators of the shoulder to speed of the fastball in college baseball pitchers : a thesis ... (1989) (0)
Faculty Opinions recommendation of Evolutionarily conserved substrate substructures for automated annotation of enzyme superfamilies. (2009) (0)

This paper list is powered by the following services:

Other Resources About Janet Thornton

What Schools Are Affiliated With Janet Thornton?

Janet Thornton is affiliated with the following schools:

Janet Thornton's Academic­Influence.com Rankings

Why Is Janet Thornton Influential?

Janet Thornton's Published Works

Published Works

Other Resources About Janet Thornton

What Schools Are Affiliated With Janet Thornton?

Image Attributions

Janet Thornton's AcademicInfluence.com Rankings