Janko Kos
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Computer Science
Janko Kos's Degrees
- PhD Computer Science ETH Zurich
- Masters Computer Science University of Ljubljana
- Bachelors Computer Science University of Ljubljana
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(Suggest an Edit or Addition)Janko Kos's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The 2.0 A X‐ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. (1988) (530)
- Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody. (2007) (416)
- Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer (review). (1998) (283)
- Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor. (2014) (196)
- Cathepsins B, H, and L and their inhibitors stefin A and cystatin C in sera of melanoma patients. (1997) (192)
- Cysteine proteinase inhibitors stefin A, stefin B, and cystatin C in sera from patients with colorectal cancer: relation to prognosis. (2000) (186)
- Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer. (2002) (184)
- Serum cystatin C, a potent inhibitor of cysteine proteinases, is elevated in asthmatic patients. (2000) (178)
- Cysteine Proteinases and Their Inhibitors in Extracellular Fluids: Markers for Diagnosis and Prognosis in Cancer (2000) (172)
- Cystatins in Immune System (2012) (147)
- Prognostic significance of cathepsins B and L in primary human breast cancer. (1998) (147)
- Cysteine cathepsins (proteases)--on the main stage of cancer? (2004) (145)
- Mechanism of inhibition of papain by chicken egg white cystatin (1989) (144)
- Serum cystatin C, a new marker of glomerular filtration rate, is increased during malignant progression. (1998) (142)
- Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro. (2003) (141)
- Cysteine proteinases in cancer progression and their clinical relevance for prognosis. (1998) (136)
- Microbial and fungal protease inhibitors—current and potential applications (2012) (134)
- Proteins of higher fungi--from forest to application. (2012) (131)
- Cathepsin B immunohistochemical staining in tumor and endothelial cells is a new prognostic factor for survival in patients with brain tumors. (1999) (123)
- Regulation of the activity of lysosomal cysteine proteinases by pH-induced inactivation and/or endogenous protein inhibitors, cystatins. (1995) (116)
- Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues. (2005) (110)
- Selective suppression of cathepsin L by antisense cDNA impairs human brain tumor cell invasion in vitro and promotes apoptosis (2003) (105)
- Cathepsin B, a prognostic indicator in lymph node-negative breast carcinoma patients: comparison with cathepsin D, cathepsin L, and other clinical indicators. (2000) (104)
- Significance of cathepsin B accumulation in synovial fluid of rheumatoid arthritis. (2001) (103)
- Purification, characterization and cloning of a ricin B-like lectin from mushroom Clitocybe nebularis with antiproliferative activity against human leukemic T cells. (2009) (101)
- Lysosomal proteases cathepsins D, B, H, L and their inhibitors stefins A and B in head and neck cancer. (1995) (97)
- The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity. (2018) (94)
- Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers. (2000) (92)
- Lysosomal Enzymes, Cathepsins in Brain Tumour Invasion (2002) (92)
- Prognostic significance of cysteine proteinases cathepsins B and L and their endogenous inhibitors stefins A and B in patients with squamous cell carcinoma of the head and neck. (2000) (91)
- Development of an in-vivo active reversible butyrylcholinesterase inhibitor (2016) (90)
- Cathepsin S in tumours, regional lymph nodes and sera of patients with lung cancer: relation to prognosis (2001) (89)
- Proteases and their endogenous inhibitors in the plant response to abiotic stress (2014) (81)
- The current stage of cathepsin B inhibitors as potential anticancer agents. (2014) (80)
- The structures of native phosphorylated chicken cystatin and of a recombinant unphosphorylated variant in solution. (1993) (80)
- γ-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K/Akt and MAPK/ERK signalling pathways. (2012) (80)
- Prognostic value of cathepsins B, H, L, D and their endogenous inhibitors stefins A and B in head and neck carcinoma. (1996) (76)
- Prognostic values of cathepsin B and carcinoembryonic antigen in sera of patients with colorectal cancer. (1998) (76)
- Novel Mechanism of Cathepsin B Inhibition by Antibiotic Nitroxoline and Related Compounds (2011) (74)
- Cysteine Cathepsins as Regulators of the Cytotoxicity of NK and T Cells (2014) (73)
- Carboxypeptidase cathepsin X mediates beta2-integrin-dependent adhesion of differentiated U-937 cells. (2006) (73)
- Inhibitory properties of cystatin F and its localization in U937 promonocyte cells (2005) (71)
- Collagenolytic cathepsins of rabbit spleen: a kinetic analysis of collagen degradation and inhibition by chicken cystatin. (1987) (69)
- Poly(lactide-co-glycolide) nanoparticles as a carrier system for delivering cysteine protease inhibitor cystatin into tumor cells. (2004) (69)
- In vitro and in vivo characterization of temoporfin-loaded PEGylated PLGA nanoparticles for use in photodynamic therapy. (2012) (68)
- Cysteine Cathepsins in Tumor-Associated Immune Cells (2019) (66)
- High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas (2009) (65)
- The role of cathepsin X in cell signaling (2009) (65)
- Cysteine Cathepsins in Neurological Disorders (2014) (65)
- Intracellular proteolytic activity of cathepsin B is associated with capillary‐like tube formation by endothelial cells in vitro (2006) (65)
- Cystatin incorporated in poly(lactide-co-glycolide) nanoparticles: development and fundamental studies on preservation of its activity. (2004) (65)
- The role of cathepsin X in the migration and invasiveness of T lymphocytes (2008) (63)
- Role of Cysteine Cathepsins in Matrix Degradation and Cell Signalling (2008) (63)
- Cathepsins B and L Are Markers for Clinically Invasive Types of Meningiomas (2001) (63)
- Effect of surface charge on the cellular uptake of fluorescent magnetic nanoparticles (2012) (62)
- Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities. (2018) (61)
- Nanoscale polymer carriers to deliver chemotherapeutic agents to tumours (2005) (61)
- Cathepsin B, plasminogenactivator-inhibitor (PAI-1) and plasminogenactivator-receptor (uPAR) are prognostic factors for patients with non-small cell lung cancer. (2004) (61)
- The role of cysteine peptidases in coronavirus cell entry and replication: The therapeutic potential of cathepsin inhibitors (2020) (58)
- Neuroprotective role of γ‐enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X (2013) (58)
- Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients. (2002) (58)
- Cysteine protease cathepsin X modulates immune response via activation of β2 integrins (2008) (58)
- Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity (2015) (57)
- Gamma-enolase: a well-known tumour marker, with a less-known role in cancer (2015) (57)
- Genotoxicity of trivalent chromium in bacterial cells. Possible effects on DNA topology. (2002) (57)
- A road map for prioritizing warheads for cysteine targeting covalent inhibitors. (2018) (56)
- Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives. (2013) (56)
- Cathepsin D inactivates cysteine proteinase inhibitors, cystatins. (1988) (56)
- Immunochemical analysis of cathepsin B in lung tumours: an independent prognostic factor for squamous cell carcinoma patients (1999) (55)
- Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and β-amyloid aggregation inhibitors with neuroprotective properties. (2015) (55)
- Cysteine proteinase cathepsin H in tumours and sera of lung cancer patients: relation to prognosis and cigarette smoking (2000) (53)
- Cathepsin H Mediates the Processing of Talin and Regulates Migration of Prostate Cancer Cells* (2012) (52)
- Bivalent Carbohydrate Binding Is Required for Biological Activity of Clitocybe nebularis Lectin (CNL), the N,N′-Diacetyllactosediamine (GalNAcβ1–4GlcNAc, LacdiNAc)-specific Lectin from Basidiomycete C. nebularis* (2012) (52)
- Expression of cysteine protease inhibitors stefin A, stefin B, and cystatin C in human lung tumor tissue. (1997) (52)
- Iron‐regulated surface determinant B (IsdB) promotes Staphylococcus aureus adherence to and internalization by non‐phagocytic human cells (2013) (50)
- The cysteine proteinase inhibitor chicken cystatin is a phosphoprotein (1989) (50)
- Cystatin C as a potential marker for relapse in patients with non-Hodgkin B-cell lymphoma. (2007) (50)
- N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents. (2017) (49)
- Procoagulant properties of bare and highly PEGylated vinyl-modified silica nanoparticles. (2010) (48)
- Cathepsin B, cathepsin H, cathepsin X and cystatin C in sera of patients with early-stage and inflammatory breast cancer. (2008) (48)
- Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells. (2009) (48)
- Cystatins in cancer progression: More than just cathepsin inhibitors. (2019) (47)
- Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X (2008) (47)
- Lysosomal cysteine peptidases - Molecules signaling tumor cell death and survival. (2015) (46)
- Cathepsin B in infiltrated lymph nodes is of prognostic significance for patients with nonsmall cell lung carcinoma (2000) (46)
- Enzyme-linked immunosorbent assay for the detection of total cathepsin H in human tissue cytosols and sera. (1997) (45)
- Versatile Loops in Mycocypins Inhibit Three Protease Families* (2009) (44)
- Differentiation‐ and maturation‐dependent content, localization, and secretion of cystatin C in human dendritic cells (2005) (43)
- CTSB (cathepsin B) (2011) (43)
- NK cells shape pancreatic and oral tumor microenvironments; role in inhibition of tumor growth and metastasis. (2018) (42)
- Structural Basis of Trypsin Inhibition and Entomotoxicity of Cospin, Serine Protease Inhibitor Involved in Defense of Coprinopsis cinerea Fruiting Bodies* (2011) (41)
- Cysteine proteinase inhibitor cystatin C in squamous cell carcinoma of the head and neck: relation to prognosis (2004) (41)
- Basidiomycete Clitocybe nebularis is rich in lectins with insecticidal activities (2011) (41)
- Cysteine cathepsins: regulators of antitumour immune response (2006) (40)
- Natural Killer Cells: Diverse Functions in Tumor Immunity and Defects in Pre-neoplastic and Neoplastic Stages of Tumorigenesis (2019) (40)
- Intracellular signaling by cathepsin X: molecular mechanisms and diagnostic and therapeutic opportunities in cancer. (2015) (40)
- Cystatins in non-small cell lung cancer: tissue levels, localization and relation to prognosis. (2006) (40)
- Cystatin F Affects Natural Killer Cell Cytotoxicity (2017) (40)
- Regulation of split anergy in natural killer cells by inhibition of cathepsins C and H and cystatin F (2015) (39)
- Trypsin-specific inhibitors from the basidiomycete Clitocybe nebularis with regulatory and defensive functions. (2009) (39)
- Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells. (2012) (39)
- Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents. (2018) (38)
- Twenty-four hour variations of cystatin C and total cysteine proteinase inhibitory activity in sera from healthy subjects. (2000) (38)
- Cathepsin B/Cystatin C Complex Levels in Sera from Patients with Lung and Colorectal Cancer (2001) (38)
- Cathepsin B and its inhibitor stefin A in brain tumors (2000) (38)
- Expression, proliferation activity and clinical significance of cathepsin B and cathepsin L in operated lung cancer. (2003) (37)
- Serum cystatin C in patients with head and neck carcinoma. (2004) (37)
- Cathepsin S generates soluble CX3CL1 (fractalkine) in vascular smooth muscle cells (2013) (37)
- Fluorometric Microassays for the Determination of Cathepsin L and Cathepsin S Activities in Tissue Extracts (1999) (37)
- Serum concentration and circadian profiles of cathepsins B, H and L, and their inhibitors, stefins A and B, in asthma. (2001) (35)
- Natural killer cells target and differentiate cancer stem-like cells/undifferentiated tumors: strategies to optimize their growth and expansion for effective cancer immunotherapy. (2018) (35)
- Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness (2009) (34)
- A novel β‐trefoil lectin from the parasol mushroom (Macrolepiota procera) is nematotoxic (2014) (33)
- Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells (2014) (33)
- Three‐dimensional invasion of macrophages is mediated by cysteine cathepsins in protrusive podosomes (2012) (32)
- Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease. (2019) (32)
- The expression of lysosomal proteinases and their inhibitors in breast cancer: Possible relationship to prognosis of the disease (2008) (32)
- Cysteine cathepsins B and X promote epithelial-mesenchymal transition of tumor cells. (2017) (31)
- Internalization of Exogenous Cystatin F Supresses Cysteine Proteases and Induces the Accumulation of Single-chain Cathepsin L by Multiple Mechanisms* (2011) (31)
- Clinical and Experimental Studies of Cysteine Cathepsins and Their Inhibitors in Human Brain Tumors (2000) (31)
- Profilin 1 as a Target for Cathepsin X Activity in Tumor Cells (2013) (30)
- Invasion of ras-Transformed Breast Epithelial Cells Depends on the Proteolytic Activity of Cysteine and Aspartic Proteinases (2001) (29)
- Proinflammatory effects of bare and PEGylated ORMOSIL-, PLGA- and SUV-NPs on monocytes and PMNs and their modulation by f-MLP. (2011) (29)
- Clioquinol-ruthenium complex impairs tumour cell invasion by inhibiting cathepsin B activity. (2016) (28)
- The balance between extracellular cathepsins and cystatin C is of importance for ovarian cancer (2010) (28)
- Mycoplasma gallisepticum and Mycoplasma synoviae express a cysteine protease CysP, which can cleave chicken IgG into Fab and Fc. (2011) (27)
- Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B (2020) (27)
- Inhibition of endopeptidase and exopeptidase activity of cathepsin B impairs extracellular matrix degradation and tumour invasion (2016) (27)
- Serum cathepsin H as a potential prognostic marker in patients with colorectal cancer. (2004) (27)
- Gamma-1-Syntrophin Mediates Trafficking of Gamma-Enolase towards the Plasma Membrane and Enhances Its Neurotrophic Activity (2011) (27)
- Organoruthenated Nitroxoline Derivatives Impair Tumor Cell Invasion through Inhibition of Cathepsin B Activity (2019) (26)
- Clitocypin, a fungal cysteine protease inhibitor, exerts its insecticidal effect on Colorado potato beetle larvae by inhibiting their digestive cysteine proteases. (2015) (26)
- DC‐SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function (2011) (25)
- Cathepsin X cleavage of the β2 integrin regulates talin‐binding and LFA‐1 affinity in T cells (2011) (25)
- Cysteine cathepsins B, X and K expression in peri-arteriolar glioblastoma stem cell niches (2018) (25)
- Natural killer cells as effectors of selection and differentiation of stem cells: Role in resolution of inflammation (2014) (25)
- Inhibition of the growth of colorado potato beetle larvae by macrocypins, protease inhibitors from the parasol mushroom. (2013) (24)
- Characterization of two novel subtilases from common bean (Phaseolus vulgaris L.) and their responses to drought. (2013) (24)
- Targeting EGFR-overexpressed A431 cells with EGF-labeled silica-coated magnetic nanoparticles (2013) (24)
- Inactivation of harmful tumour-associated proteolysis by nanoparticulate system. (2009) (24)
- Circadian and concentration profile of cathepsin S in sera from healthy subjects and asthmatic patients (2001) (24)
- CNL, a ricin B‐like lectin from mushroom Clitocybe nebularis, induces maturation and activation of dendritic cells via the toll‐like receptor 4 pathway (2011) (23)
- Cystatin F as a regulator of immune cell cytotoxicity (2018) (23)
- The influence of macro- and microelements in seminal plasma on diluted boar sperm quality (2017) (23)
- Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors (2009) (22)
- Redox-Based Inactivation of Cysteine Cathepsins by Compounds Containing the 4-Aminophenol Moiety (2011) (22)
- Immunonanoparticles − an effective tool to impair harmful proteolysis in invasive breast tumor cells (2007) (22)
- Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation (2017) (22)
- Interaction of human cathepsin C with chicken cystatin (1996) (21)
- Isolation and characterisation of chicken L- and H-kininogens and their interaction with chicken cysteine proteinases and papain. (1992) (21)
- Cathepsin X cleaves the β2 cytoplasmic tail of LFA‐1 inducing the intermediate affinity form of LFA‐1 and α‐actinin‐1 binding (2009) (21)
- Cathepsin X in serum from patients with colorectal cancer: relation to prognosis (2012) (20)
- Fungal lectin MpL enables entry of protein drugs into cancer cells and their subcellular targeting (2017) (20)
- Molecular dynamics to enhance structure-based virtual screening on cathepsin B (2015) (20)
- Cathepsin B/Cystatin C Complex Levels in Sera from Patients with Lung and Colorectal Cancer (2001) (20)
- Detection by ELISA of the humoral immune response in rabbits naturally infected with Trichophyton mentagrophytes. (1999) (19)
- LFA‐1 fine‐tuning by cathepsin X (2011) (19)
- Immunochemical Localisation of Cathepsin S, Cathepsin L and MHC Class II-Associated p41 Isoform of Invariant Chain in Human Lymph Node Tissue (2001) (19)
- Cathepsin B inhibitors: Further exploration of the nitroxoline core. (2018) (19)
- Inhibitory p41 isoform of invariant chain and its potential target enzymes cathepsins L and H in distinct populations of macrophages in human lymph nodes (2004) (19)
- Invasion of ras-Transformed Breast Epithelial Cells Depends on the Proteolytic Activity of Cysteine and Aspartic Proteinases (2001) (18)
- Cysteine cathepsins: Their biological and molecular significance in cancer stem cells (2018) (18)
- N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. (2020) (18)
- Synthesis of a (desSer1 Ile29 Leu89) chicken cystatin gene, expression in E. coli as fusion protein and its isolation (1989) (18)
- Cathepsin X-mediated β2 integrin activation results in nanotube outgrowth (2009) (17)
- A new purification procedure of human kidney cathepsin H, its properties and kinetic data. (1988) (17)
- Cysteine Cathepsins and Cystatins as Cancer Biomarkers (2008) (17)
- Cystatins, cysteine peptidase inhibitors, as regulators of immune cell cytotoxicity (2017) (16)
- Cathepsin X prevents an effective immune response against Helicobacter pylori infection. (2009) (16)
- Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients (2014) (16)
- Prognostic value of cathepsins B, D and stefins A and B in laryngeal carcinoma (2006) (16)
- Cathepsin X Cleaves Profilin 1 C-Terminal Tyr139 and Influences Clathrin-Mediated Endocytosis (2015) (16)
- Regulation of cathepsin B activity by 2A2 monoclonal antibody (2009) (16)
- Nitroxoline: repurposing its antimicrobial to antitumor application. (2019) (16)
- Discovery and kinetic evaluation of 6-substituted 4-benzylthio-1,3,5-triazin-2(1H)-ones as inhibitors of cathepsin B. (2011) (15)
- Increased Cystatin F Levels Correlate with Decreased Cytotoxicity of Cytotoxic T Cells (2019) (15)
- Stefin a and stefin B: markers for prognosis in operable squamous cell carcinoma of the head and neck. (2007) (15)
- Cathepsin B, Cathepsin H, Cathepsin X and Cystatin C in Sera of Patients with Early-Stage and Inflammatory Breast Cancer (2008) (14)
- Identification and characterization of the novel reversible and selective cathepsin X inhibitors (2017) (14)
- Serum-specific antibodies in rabbits naturally infected with Trichophyton mentagrophytes. (2003) (14)
- The transcription factor C/EBP α controls the role of cystatin F during the differentiation of monocytes to macrophages. (2018) (14)
- Localization Patterns of Cathepsins K and X and their Predictive Value in Glioblastoma (2018) (14)
- C-Terminal Peptide of γ-Enolase Impairs Amyloid-β-Induced Apoptosis Through p75NTR Signaling (2013) (14)
- Cytotoxic L-amino-acid oxidases from Amanita phalloides and Clitocybe geotropa induce caspase-dependent apoptosis (2016) (13)
- Expression of stefin A is of prognostic significance in squamous cell carcinoma of the head and neck (2013) (13)
- Thermal denaturation of human cystatin C and two of its variants; comparison to chicken cystatin. (1997) (13)
- The Role of Cysteine Peptidases in Hematopoietic Stem Cell Differentiation and Modulation of Immune System Function (2021) (13)
- Protease inhibitors clitocypin and macrocypin are differentially expressed within basidiomycete fruiting bodies. (2011) (13)
- Circadian characteristics of cathepsins B, H, L, and stefins A and B, potential markers for disease, in normal sera. (1999) (13)
- Aqueous Extracts of Wild Mushrooms Show Antimicrobial and Antiadhesion Activities against Bacteria and Fungi (2017) (12)
- Intracellular delivery of cysteine protease inhibitor cystatin by polymeric nanoparticles. (2006) (12)
- Pyrimido[1,2-b]indazole derivatives: Selective inhibitors of human monoamine oxidase B with neuroprotective activity. (2020) (12)
- β-Trefoil structure enables interactions between lectins and protease inhibitors that regulate their biological functions. (2015) (11)
- Nanotechnology in the treatment of cancer (2010) (11)
- Addition of 2-(ethylamino)acetonitrile group to nitroxoline results in significantly improved anti-tumor activity in vitro and in vivo. (2017) (11)
- Affinity Chromatography of Lectins (2012) (11)
- Fungal β-trefoil trypsin inhibitors cnispin and cospin demonstrate the plasticity of the β-trefoil fold. (2014) (10)
- Inhibition of cathepsin X enzyme influences the immune response of THP-1 cells and dendritic cells infected with Helicobacter pylori (2013) (10)
- Cysteine protease-mediated cytoskeleton interactions with LFA-1 promote T-cell morphological changes. (2009) (10)
- Efficient removal of cathepsin L from active cathepsin X using immunoprecipitation technique (2009) (10)
- The response of aminopeptidases of Phaseolus vulgaris to drought depends on the developmental stage of the leaves. (2016) (9)
- The Predictive Value of Cystatin C in Monitoring of B Non-Hodgkin Lymphomas: Relation to Biochemical and Clinical Parameters (2013) (9)
- Multiple Defects of Natural Killer Cells in Cancer Patients: Anarchy, Dysregulated Systemic Immunity, and Immunosuppression in Metastatic Cancer. (2020) (9)
- Improved Acylation Method Enables Efficient Delivery of Functional Palmitoylated Cystatin into Epithelial Cells (2007) (9)
- The influence of differential processing of procathepsin H on its aminopeptidase activity, secretion and subcellular localization in human cell lines. (2012) (9)
- Monoclonal antibody to cytokeratin VKIALEVEIATY sequence motif reduces plasminogen activation in breast tumour cells. (2008) (8)
- Lysosomal peptidases in innate immune cells: implications for cancer immunity (2019) (8)
- 8-Hydroxyquinoline-based anti-Alzheimer multimodal agents (2020) (8)
- Cathepsin H indirectly regulates morphogenetic protein-4 (BMP-4) in various human cell lines (2011) (7)
- Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo (2020) (7)
- Infuence of Culinary-Medicinal Maitake Mushroom, Grifola frondosa (Dicks.: Fr.) S.F. Gray (Aphyllophoromycetideae) Polysaccharides on Gene Expression in Jurkat T Lymphocytes (2010) (7)
- Addition of 2-(ethylamino)acetonitrile group to nitroxoline results in significantly improved anti-tumor activity in vitro and in vivo (2017) (7)
- Lysosomal Cysteine Proteases and Their Protein Inhibitor (2002) (7)
- Antibacterial Activity of Wild Mushroom Extracts on Bacterial Wilt Pathogen Ralstonia solanacearum. (2016) (7)
- Interrelated cathepsin S-lowering and LDL subclass profile improvements induced by atorvastatin in the plasma of stable angina patients. (2014) (7)
- CNL–Clitocybe nebularis Lectin—The Fungal GalNAcβ1-4GlcNAc-Binding Lectin (2019) (7)
- L-Amino Acid Oxidases From Mushrooms Show Antibacterial Activity Against the Phytopathogen Ralstonia solanacearum (2020) (7)
- Serum Cathepsin H as a Potential Prognostic Marker in Patients with Colorectal Cancer (2004) (7)
- Targeting of fluorescent Lactococcus lactis to colorectal cancer cells through surface display of tumour‐antigen binding proteins (2021) (6)
- Relationship of High Circulating Cystatin C to Biochemical Markers of Bone Turnover and Bone Mineral Density in Elderly Males with a Chronic Heart Failure (2018) (6)
- Levels of Cathepsins S and H in Pleural Fluids of Inflammatory and Neoplastic Origin (2009) (6)
- Nanoparticle Based Delivery of Protease Inhibitors to Cancer Cells. (2018) (6)
- Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 – Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes (2022) (6)
- Cell models for Alzheimer's and Parkinson's disease: At the interface of biology and drug discovery. (2022) (6)
- Extracellular Cystatin F Is Internalised by Cytotoxic T Lymphocytes and Decreases Their Cytotoxicity (2020) (6)
- Medicinal Properties of the Genus Clitocybe and of Lectins from the Clouded Funnel Cap Mushroom, C. nebularis (Agaricomycetes): A Review. (2016) (6)
- Cathepsins and cystatins in extracellular fluids-useful biological markers in cancer (2002) (6)
- Levels of cathepsins S and H in pleural fluids of inflammatory and neoplastic origin. (2009) (6)
- Cysteine cathepsins L and X differentially modulate interactions between myeloid-derived suppressor cells and tumor cells (2020) (6)
- Differences in the Antigens of Helicobacter pylori Strains Influence on the Innate Immune Response in the In Vitro Experiments (2014) (6)
- Elimination of apoptotic boar spermatozoa using magnetic activated cell sorting (2014) (5)
- New Insights into the Role of Cysteine Cathepsins in Neuroinflammation (2021) (5)
- Upregulation of Cysteine Protease Cathepsin X in the 6-Hydroxydopamine Model of Parkinson’s Disease (2018) (5)
- Evaluation of novel cathepsin-X inhibitors in vitro and in vivo and their ability to improve cathepsin-B-directed antitumor therapy (2022) (5)
- Natural Apocarotenoids and Their Synthetic Glycopeptide Conjugates Inhibit SARS-CoV-2 Replication (2021) (5)
- Synthesis of Novel Nitroxoline Analogs with Potent Cathepsin B Exopeptidase Inhibitory Activity (2020) (5)
- Serum cysteine proteases and their inhibitors in rheumatoid arthritis: relation to disease activity and radiographic progression (2011) (5)
- Lysosomal peptidases—intriguing roles in cancer progression and neurodegeneration (2022) (5)
- Plasma Cathepsin S is Associated with High-density Lipoprotein Cholesterol and Bilirubin in Patients with Abdominal Aortic Aneurysms (2019) (4)
- Proteolytic Profile of Cysteine Proteases and Inhibitors Determines Tumor Cell Phenotype in Squamous Cell Carcinoma of the Head and Neck (2011) (4)
- Versatile loops in mycocypins inhibit three protease families (2011) (4)
- Biological Evaluation of 8-Hydroxyquinolines as Multi-Target Directed Ligands for Treating Alzheimer's Disease. (2019) (4)
- The Value of Fungal Protease Inhibitors in Affinity Chromatography (2012) (4)
- Genistein , a phytoestrogen in soybean , induces the expression of acetylcholinesterase via G protein-coupled receptor 30 in PC 12 cells (2018) (4)
- ?-Trefoil Protease Inhibitors Unique to Higher Fungi. (2019) (3)
- Higher fungi are a rich source of l-amino acid oxidases (2017) (3)
- Cystatin C in sera of patients with aggressive non-Hodgkin B-cell lymphoma. (2011) (3)
- The Carboxypeptidase Activity of Cathepsin X is not Controlled by Endogenous Inhibitors. (2019) (3)
- Fungal Protease Inhibitors (2015) (3)
- Cysteine and aspartic proteases cathepsins B and D determine the invasiveness of MCF10A neoT cells (2003) (3)
- Structure-activity relationships of triazole-benzodioxine inhibitors of cathepsin X. (2020) (3)
- Cysteine proteinase inhibitors stefin A and stefin B in operable carcinoma of the head and neck (2002) (3)
- Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors (2022) (3)
- Cystatin F acts as a mediator of immune suppression in glioblastoma (2021) (3)
- Trypsin-specific Inhibitors from the Macrolepiota procera, Armillaria mellea and Amanita phalloides wild mushrooms. (2017) (3)
- Cysteine cathepsins B and L and their inhibitors stefins A and B in carcinoma of the oropharynx: immunohistochemical study (2008) (3)
- CSTB (cystatin B (stefin B)) (2011) (3)
- Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria (2022) (2)
- Histological and thermodynamical features of cathepsin B-positive tumors of non-small cell lung cancer obtained by syntactic structure analysis (2001) (2)
- Cysteine Peptidase Cathepsin X as a Therapeutic Target for Simultaneous TLR3/4-mediated Microglia Activation (2022) (2)
- Cathepsin X Activity Does Not Affect NK-Target Cell Synapse but Is Rather Distributed to Cytotoxic Granules (2021) (2)
- Refolding of recombinant sulphonated procathepsin S and of reduced chicken cystatin; implications for renaturation experiments. (1998) (2)
- Human CD4+ T-Cell Clone Expansion Leads to the Expression of the Cysteine Peptidase Inhibitor Cystatin F (2021) (2)
- Characterization of monoclonal antibodies against MHC class II-associated p41 invariant chain fragment (2002) (2)
- Immunochemical Localisation of Cathepsin S, Cathepsin L and MHC Class II-Associated p41 Isoform of Invariant Chain in Human Lymph Node Tissue (2001) (2)
- Isolation and characterization of chicken egg white low-Mr kininogen (1986) (2)
- Chicken egg white cystatin as a ligand for affinity chromatography (1986) (2)
- Immunonanoparticles for targeting and delivery of protein drugs into tumour cells (2008) (2)
- The effect of endocrine disrupting chemicals on the vitronectin-receptor (integrin αvβ3)-mediated cell adhesion of human umbilical vein endothelial cells (2021) (2)
- Molecular cloning and chimerisation of CDI 315B monoclonal antibody (2000) (2)
- Helicobacter pylori Susceptible/Resistant to Antibiotic Eradication Therapy Differ in the Maturation and Activation of Dendritic Cells (2013) (2)
- Refolding of chicken cystatin and human stefin A studied by fast protein liquid chromatography (FPLC). (1990) (2)
- New inhibitors of cathepsin V impair tumor cell proliferation and elastin degradation and increase immune cell cytotoxicity (2022) (1)
- M-THPC delivery via pegylated plga nanoparticles for in vivo photodynamic therapy (PDT) (2013) (1)
- Proteases: Role and Function in Cancer (2022) (1)
- Indoles and 1-(3-(benzyloxy)benzyl)piperazines: Reversible and selective monoamine oxidase B inhibitors identified by screening an in-house compound library. (2021) (1)
- 8- Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases (2023) (1)
- Cocaprins, β-Trefoil Fold Inhibitors of Cysteine and Aspartic Proteases from Coprinopsis cinerea (2022) (1)
- CSTA (cystatin A (stefin A)) (2011) (1)
- Modulation of adhesion processes with endocrine disruptors: The cases of bisphenol AF and triclosan (2015) (1)
- Microbial and fungal protease inhibitors—current and potential applications (2012) (1)
- Distribution of the egg white cystatin in chicken (1986) (1)
- Molecular cloning and chimerisation of CDI 315B monoclonal antibody (2000) (1)
- 2 The Refined X-Ray Crystal Structures of Human and Rat Liver Cathepsin B (1994) (1)
- Effects of tyrosine kinase inhibitors on androgen, estrogen α, glucocorticoid and thyroid receptors. (2021) (1)
- Molecular Cloning and Chimerisation of an Inhibitory Anti-Cathepsin B Antibody and Its Expression in Chinese Hamster Ovary Cells (2002) (1)
- The fungal Clitocybe nebularis lectin binds distinct cell surface glycoprotein receptors to induce cell death selectively in Jurkat cells (2022) (1)
- Increased Plasma Cathepsin s at the Time of Percutaneous Transluminal Angioplasty is Associated with 6-months’ Restenosis of the Femoropopliteal Artery (2018) (1)
- Myeloid-Derived Suppressor Cells Hamper Natural Killer Cell Activity in Cancer: Role of Peptidases. (2021) (1)
- γ-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells (2021) (1)
- Proteinase inhibitor from Coprinopsis cinerea (2011) (0)
- The role of peptidases and their endogenous inhibitors in the regulation of NK cell cytotoxicity (2021) (0)
- BUTYRYLCHOLINESTERASE INHIBITORS GRAFTED WITH ANTIOXIDANT AND NEUROPROTECTIVE ACTIVITIES: NOVEL MULTIFUNCTIONAL LIGANDS FOR ALZHEIMER’S DISEASE (2018) (0)
- Serum cathepsins B, D, L and their inhibitors stef in A and cystatin C in melanoma patients: 334 (1997) (0)
- Cover Picture: Eur. J. Immunol. 11/09 (2009) (0)
- Evaluation of novel cathepsin-X inhibitors in vitro and in vivo and their ability to improve cathepsin-B-directed antitumor therapy (2022) (0)
- Cathepsin B and its inhibitor stefin A in brain tumors (2000) (0)
- CTSH (cathepsin H) (2011) (0)
- Cysteine Cathepsins in Neurological Disorders (2013) (0)
- 714 Expression of cathepsins and stefins in lung tumor tissue (1997) (0)
- 1st Workshop on Experimental Tumour Biology (2002) (0)
- Clitocybe nebularis ricin B-like lectin (CNL) in complex with lactose, crystallized at pH 7.1 (2011) (0)
- γ-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells (2021) (0)
- MOLECULAR MODELING IN SEARCH OF NEW, MULTI-TARGET LIGANDS AGAINST ALZHEIMER'S DISEASE. EXPLORING THE BIOCHEMICAL MULTIVERSE. (2018) (0)
- Possible use of antimicrobial agents in cancer therapy (2022) (0)
- Cathepsin B and its inhibitor stefin A in brain tumors. (2000) (0)
- The Predictive Value of Cystatin C in Monitoring of B Non-Hodgkin Lymphomas : Relation to Biochemical and Clinical Parameters (2015) (0)
- C-Terminal Peptide of γ-Enolase Impairs Amyloid-β-Induced Apoptosis Through p75NTR Signaling (2013) (0)
- Crystal structure of human monoamine oxidase B in complex with styrylpiperidine analogue 1 (2020) (0)
- Macrolepiota procera ricin B-like lectin (MPL) (2013) (0)
- Cysteine cathepsins B, X and K expression in peri-arteriolar glioblastoma stem cell niches (2018) (0)
- Molecular cloning and chimerisation of CDI 315B monoclonal antibody. (2000) (0)
- CHICKEN EGG WHITE CYSTATIN WILDTYPE, NMR, 16 STRUCTURES (1998) (0)
- Title : Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients (2014) (0)
- The level of Cat S is increased and HDL-C is decreased at the same time in plasma of patients with abdominal aortic aneurysm and aortoiliac occlusive disease (2018) (0)
- PEGylated poly(lactide-co-glycolide) nanoparticles loaded with meta-tetra(hydroxyphenyl)chlorin for photodynamic treatment of cancer (2011) (0)
- Cysteine Cathepsins as Therapeutic Targets in Immune Regulation and Immune Disorders (2023) (0)
- Identification and characterization of the novel reversible and selective cathepsin X inhibitors (2017) (0)
- Circadian rhythms of cysteine proteinases and cystatins, potential tumour markers, in normal sera (2002) (0)
- Peptidases: Role and Function in Health and Disease (2023) (0)
- RECOMBINANT MUTANT CHICKEN EGG WHITE CYSTATIN, NMR, 31 STRUCTURES (1998) (0)
- Sequential therapy with supercharged NK cells with either chemotherapy drug cisplatin or anti-PD-1 antibody decreases the tumor size and significantly enhances the NK function in Hu-BLT mice (2023) (0)
- Carboxypeptidase Cathepsin X Defines a Multifunctional Role of Gamma- Enolase in Cancer (2022) (0)
- A dodecapeptide deduced from cytokeratin sequence strongly enhances uPA/tPA‐mediated plasminogen activation (2010) (0)
- Macrolepiota procera ricin B-like lectin (MPL) in complex with Di-LacNAc (2013) (0)
- PREPARATION OF FLUORESCENT, FUNCTIONALIZED, SILICA-COATED MAGNETIC NANOPARTICLES MARKED WITH MONOCLONAL ANTIBODIES (2009) (0)
- Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients (2014) (0)
- Clitocybe nebularis ricin B-like lectin (CNL) in complex with lactose, crystallized at pH 4.4 (2011) (0)
- 154 Cysteine proteinase inhibitor cystatin C (CC) in operable squamous cell carcinoma of the head and neck (SCCHN): expression pattern and relation to prognosis (2003) (0)
- LAH (2020) (0)
- The effect of E-64 and monoclonal antibodies on proliferative and invasive activity of ras transformed human breast epithelial cell line MCF10A neoT tested in in vitro assays (2002) (0)
- Novel strategies to expand supercharged NK cells with augmented capacity to withstand inactivation by tumors (2021) (0)
- Kos (2021) (0)
- Cathepsin B in complex with the nitroxoline (2011) (0)
- Therapeutic potential of inhibition of the neuroinflammation induced cathepsin X: in vivo evidence (2019) (0)
- Myotoxic phospholipase A2 homologue from long-nosed viper venom (1995) (0)
- Clitocybe nebularis ricin B-like lectin (CNL) in complex with N,N'-diacetyllactosediamine (2011) (0)
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What Schools Are Affiliated With Janko Kos?
Janko Kos is affiliated with the following schools:
