Jarle Aarbakke

Jarle Aarbakke's AcademicInfluence.com Rankings

Jarle Aarbakke

Chemistry

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#6969

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Chemistry

Why Is Jarle Aarbakke Influential?

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According to Wikipedia, Jarle Aarbakke was the rector at the University of Tromsø from 2002 until 2013, and the mayor of Tromsø municipality from October 2015 to July 2016 Before being elected rector in 2001, Aarbakke served as a professor of pharmacy at the Department of Medical Microbiology. From 2007 to 2009 he was chair of the Norwegian Association of Higher Education Institutions .

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Jarle Aarbakke's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms (1997) (403)
Thiopurine biology and pharmacology. (1997) (111)
Interethnic difference in thiopurine methyltransferase activity (1992) (70)
Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide (1996) (59)
The role of liver alcohol dehydrogenase isoenzymes in the oxidation of glycolethers in male and female rats. (1998) (58)
A new flow cytometric method for discrimination of apoptotic cells and detection of their cell cycle specificity through staining of F-actin and DNA. (1995) (57)
Amiodarone inhibits the conversion of thyroxine to triiodothyronine in isolated rat hepatocytes. (1984) (54)
Detection of one single mutation predicts thiopurine S‐methyltransferase activity in a population of Saami in northern Norway (2001) (52)
Renal elimination of protein S-100beta in pigs with acute encephalopathy. (2001) (52)
Thiopurine methyltransferase activity in a Korean population sample of children (1996) (47)
Methotrexate measurements in plasma: comparison of enzyme multiplied immunoassay technique, TDx fluorescence polarization immunoassay, and high pressure liquid chromatography. (1986) (47)
Clinical Pharmacokinetics of Phenylbutazone (1978) (46)
Dose-dependent pharmacokinetics of methotrexate and 7-hydroxymethotrexate in the rat in vivo. (1989) (43)
High-dose 7-hydroxymethotrexate: Acute toxicity and lethality in a rat model (2009) (42)
The interaction of 6-mercaptopurine (6-MP) and methotrexate (MTX). (1999) (41)
Formation and elimination of 7-hydroxymethotrexate in the rat in vivo after methotrexate administration. (1989) (35)
Hepatic microsomal drug metabolism, glutamyl transferase activity and in vivo antipyrine half-life in rats chronically fed an ethanol diet, a control diet and a chow diet. (1980) (35)
Induction of HL-60 cell differentiation by 3-deaza-(+/-)-aristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase. (1986) (35)
14C-antipyrine as a model compound in the study of drug oxidation and enzyme induction in individual surviving rats. (2009) (34)
Value of urinary simple phenol and indican determinations in the diagnosis of the stagnant loop syndrome. (1976) (33)
Synergistic increase in c-fos expression by simultaneous activation of the ras/raf/map kinase- and protein kinase A signaling pathways is mediated by the c-fos AP-1 and SRE sites. (1998) (33)
Hydroxychloroquine in human breast milk (2004) (32)
Gender difference in red blood cell thiopurine methyltransferase activity. (1993) (30)
Effects of diethyl ether anaesthesia on the pharmacokinetics of antipyrine and paracetamol in the rat (1981) (29)
Identification of factors regulating thiopurine methyltransferase activity in a Norwegian population (2004) (28)
Possibilities for therapeutic drug monitoring of azathioprine: 6-thioguanine nucleotide concentrations and thiopurine methyltransferase activity in red blood cells. (1997) (27)
Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine. (1993) (24)
Effects of low dose propranolol after coronary bypass surgery. (1984) (23)
Maximum tolerated doses of methotrexate and 7-hydroxy-methotrexate in a model of acute toxicity in rats (2000) (23)
PHARMACOKINETIC INTERACTIONS WITH METHOTREXATE: IS 7-HYDROXY-METHOTREXATE THE CULPRIT? (1988) (23)
Disposition and oxidative metabolism of antipyrine in the rat. (2009) (22)
Homocysteine increases the relative number of apoptotic cells and reduces the relative number of apoptotic bodies in HL-60 cells treated with 3-deazaadenosine. (1994) (21)
The c-fos cAMP-response element: regulation of gene expression by a beta 2-adrenergic agonist, serum and DNA methylation. (1993) (20)
Low catechol-O-methyltransferase activity in a Saami population (2004) (20)
Increased concentrations of methylated 6-mercaptopurine metabolites and 6-thioguanine nucleotides in human leukemic cells in vitro by methotrexate. (1998) (20)
Pharmacokinetics of 7-hydroxy-methotrexate and methotrexate in the rat. (1988) (20)
Acute hepatotoxicity after high-dose methotrexate administration to rats. (1991) (19)
Sex-dependent induction of alcohol dehydrogenase activity in rats. (1999) (18)
Antipyrine and acetaminophen kinetics in the rat: comparison of data based on blood samples from the cut tail and a cannulated femoral artery. (1982) (18)
Pharmacokinetics of methotrexate and 7-hydroxy-methotrexate after high-dose (33.6 g/m2) methotrexate therapy. (1986) (17)
High-dose methotrexate therapy (6-8 g/m2) in childhood malignancies: clinical tolerability and pharmacokinetics. (1987) (17)
Interaction of S-adenosylhomocysteine with isolated rat hepatocytes. (1981) (17)
Effects of cAMP and cGMP elevating agents on HL-60 cell differentiation. (1994) (17)
Microvascular Perturbations in Rats Receiving the Maximum Tolerated Dose of Methotrexate or Its Major Metabolite 7-Hydroxymethotrexate (2000) (17)
Gender difference in the elimination of 2-methoxyethanol, methoxyacetic acid and ethoxyacetic acid in rat. (1997) (16)
Body fat as a predictor of the antihypertensive effect of nifedipine (1995) (16)
Renal and hepatic toxicity after high-dose 7-hydroxymethotrexate in the rat (2004) (15)
Disposition and oxidative metabolism of phenylbutazone in man (2004) (15)
Metabolism of 14C-antipyrine in suspensions of isolated rat liver cells. (2009) (14)
Illustrated Pharmacology for Nurses (2006) (14)
Analysis of methylated 6-mercaptopurine metabolites in human red blood cells: comparison of two methods. (1997) (14)
Intraindividual variability in red blood cell thiopurine methyltransferase activity (1996) (13)
Effect of diethylether on the formation of paracetamol sulphate and glucuronide in isolated rat hepatocytes. (1984) (13)
Lack of effect of fever on antipyrine oxidation in the rat. (1978) (12)
Apoptosis and transmethylation metabolites in HL-60 cells. (1996) (11)
Effects of 3-deazaadenosine on human promyelocytic HL-60 cells (1985) (11)
Tumor Cell Differentiation (1987) (10)
No effect of acute ethanol administration on hepatic protein synthesis and export in the rat in vivo. (1984) (10)
Interactions with the protein binding of 7-hydroxy-methotrexate in human serum in vitro. (1988) (10)
Morphological modifications of apoptosis in HL-60 cells: effects of homocysteine and cytochalasins on apoptosis initiated by 3-deazaadenosine (2004) (10)
Differential cell cycle perturbation by transmethylation inhibitors. (1990) (10)
Characterization of S-adenosylhomocysteine binding to isolated rat hepatocytes and purified rat liver plasma membranes. Effect of analogues of S-adenosylhomocysteine. (1982) (10)
Bioavailability of naproxen sodium suppositories. (1984) (10)
The effect of antineoplastic drugs on the pharmacokinetics of antipyrine in the rat. (2009) (10)
[In search of a cure]. (1992) (10)
The effect of vindesine on methotrexate hydroxylation in the rat. (1991) (9)
Growth, differentiation and the beta-adrenergic signal system of HL-60 cells. Characterization in a medium with insulin as the only added protein. (1989) (9)
Increased oxidation of phenylbutazone during hydrocortisone infusion in man. (1977) (8)
Excretion of gold into human breast milk (2004) (8)
Microsomal metabolism of antipyrine in rats treated with antineoplastic drugs. (1983) (8)
Is there a gender difference in red blood cell thiopurine methyltransferase activity in healthy children? (1995) (7)
LEUCOVORIN AND MAXIMUM TOLERATED DOSE TOXICITY OF METHOTREXATE IN RATS (2000) (7)
DNA-methylation in HL-60 cells treated with 3-deaza-(+/-)-aristeromycin and 3-deazaadenosine. (1989) (7)
Differentiation of Human Leukemia Cells by Nucleoside Analogues (1987) (7)
An improved microscale HPLC assay for naproxen plasma levels. (2009) (7)
Effect of posture on ampicillin pharmacokinetics, glomerular filtration rate and renal plasma flow in resting subjects. (1983) (7)
Methotrexate increases red blood cell concentrations of 6-methylmercaptopurine ribonucleotide in rats in vivo (1997) (7)
Pharmacokinetics of naproxen after oral administration of two tablet formulations in healthy volunteers. (1983) (6)
Effect of the glutathione/glutathione disulfide redox couple on thiopurine methyltransferase. (2001) (6)
A simple HPLC method for measuring metoclopramide in serum. (2009) (6)
Elevation of cyclic AMP levels in HL-60 cells accumulated in G1 or G2 by transmethylation inhibitors. (1991) (6)
A Three Dimensional Model of Human Thiopurine Methyltransferase; Ligand Interactions and Structural Consequences of Naturally Occurring Mutations (1998) (5)
The effect of calcium channel blockers and calcium on methotrexate accumulation in rat hepatocytes. (1995) (5)
Effects of 3-deazaadenosine on apoptosis-related gene transcripts in HL-60 cells. (1997) (5)
[Injuries and drug use among soccer players]. (1996) (5)
Interactions of vinblastine and vincristine with methotrexate transport in isolated rat hepatocytes (2004) (5)
Epinephrine induces β-adrenergic desensitization and differentiation of HL-60 cells (1993) (5)
Tumor Cell Differentiation: Biology and Pharmacology (1987) (5)
Metabolism of thyroid hormones in isolated rat hepatocytes: studies on the influences of carbamazepine and phenytoin. (1983) (5)
Is there an association between an increase in c-myc RNA steady state levels and c-myc methylation in HL-60 cells treated with 3-deaza-(+/-)-aristeromycin, an indirect inhibitor of methylation? (1992) (5)
Biology and pharmacology of thiopurines. (1995) (5)
Effects of 3-deazaadenosine, an inducer of HL-60 cell differentiation, on human blood cells in vitro. (1989) (5)
Erythrocyte fraction affects red blood cell thiopurine methyltransferase activity (2004) (4)
Impaired oxidation of antipyrine in stagnant loop rats. (1977) (4)
Physiological cyclic AMP stimulation and oncogene mRNA levels in HL-60 cells. (1990) (4)
High-dose metoclopramide and chlorpromazine in the treatment of cisplatin-induced emesis. (1987) (4)
A Sensitive Gas Chromatographic Assay for Amitriptyline and Nortriptyline in Plasma (1982) (4)
Effect of Different β-Blocking Drugs and Adrenaline on the Conversion of Thyroxine to Triiodothyronine in Isolated Rat Hepatocytes (1986) (4)
An automated method for the determination of nortriptyline and its isomeric 10-hydroxylated metabolites in plasma by high pressure liquid chromatography. (1990) (3)
Binding of S-adenosylhomocysteine to various domains of the plasma membrane and to the endoplasmic reticulum from rat liver: relation between binding and phospholipid methyltransferase activity. (1983) (3)
Epinephrine induces beta-adrenergic desensitization and differentiation of HL-60 cells. (1993) (3)
Effect of anticancer drugs on drug metabolism. (1987) (3)
Therapeutic drug monitoring in oncology. (1990) (3)
Clinical effect and pharmacokinetics of trimethoprim-sulphadiazine in children with urinary tract infections (2004) (2)
Perturbation of methotrexate transport by verapamil, vinblastine, taurocholate and bromosulfophthalein in rat hepatocytes. (1995) (2)
Optimization of azathioprine therapy by measuring 6-thioguanine nucleotides and methylated mercaptopurine in renal allograft recipients. (1995) (2)
Interindividual variation in apparent volumes of distribution of antipyrine in the rat (1982) (2)
The human promyelocytic leukemia cell (HL-60 cell) beta-adrenergic receptor. (1988) (2)
Gender difference in rat hepatic biotransformation of 2-methoxyethanol, 2-ethoxyethanol and 2-buthoxy-ethanol (1996) (2)
[Caffeine--the gentle addictive stimulant]. (1995) (1)
Correlation between dna hypomethylation and differentiation of hl 60 promyelocytic cells induced by neplanocin a and 3 deaza nucleosides (1985) (1)
Inhibition of 7-hydroxymethotrexate formation by amsacrine (2004) (1)
[Melatonin--myths and reality]. (1996) (1)
Localization of microbial L-tyrosine degradation in the intestine of coprophagy-prevented rats. (1972) (1)
Beta-Adrenergic Receptors of Normal, Transformed and Immature Human Leucocytes (1987) (0)
[NOU 1998:21. Alternative medicine]. (1999) (0)
[New techniques for optimization of thiopurine therapy in leukemia and transplantation]. (2002) (0)
Elimination of methoxyethanol and methoxy acetic acid in male and female rats (1998) (0)
[Children, morbidity and drugs]. (1989) (0)
[Drugs which the physician should bring with him on the sick call]. (1979) (0)
[Individualized drug therapy]. (2000) (0)
Binding of S-adenosylhomocysteine to isolated rat hepatocytes and purified plasma membranes from rat liver (1982) (0)
[Apoptosis and cytostatic agents]. (1992) (0)
[Cancer as a late complication of cancer therapy]. (2000) (0)
Effect of different beta-blocking drugs and adrenaline on the conversion of thyroxine to triiodothyronine in isolated rat hepatocytes. (1986) (0)
[Hypertension and hypertension therapy in the elderly]. (1987) (0)
Distribution of methotrexate in human blood in vitro: independence of temperature, pH and drug concentration. (1987) (0)
7-Hydroxynsethotrexate (7-OH-MTX) induced acute hepatotoxicity (1990) (0)
[Possible deleterious effects of intestinal bacterial metabolism]. (1973) (0)
Serum theophylline levels after use of an anhydrous crystalline theophylline suppository (2004) (0)
β-adrenergic receptors of HL-60 cells: a role in differentiation induction? (1990) (0)
The effect of 3-deazaadenosine and 3-deaza-(±)-aristeromycin on c-myc methylation in HL-60 cells (1990) (0)
[Who will receive future tailor-made drugs?]. (2000) (0)
Theophylline reduces oncogene expression and induces cellular differentiation in HL-60 cells (1990) (0)
[Clinical pharmacology--a new medical specialty]. (1990) (0)
[How are my receptors, doctor?]. (2001) (0)
[Strange reaction to drug therapy]. (2003) (0)
Thiopurine methyltransferase (TPMT) pharmacogenetics: Polymorphism characterization (1997) (0)
[Distal urinary tract distress and urinary tract infections in the elderly]. (1987) (0)
Cell cycle dependence of drug initiated apoptosis in HL-60 cells. (1996) (0)
[Drugs and house calls. A considered choice]. (1980) (0)
[Pharmacological induction of leukemia cell differentiation]. (1988) (0)
[Bioavailability of strong analgesics in patients with liver diseases]. (1980) (0)
Dose-dependent Pharmacokinetics of Methotrexate and 7-Hydroxymethotrexate in the Rat in Vivo1 (2006) (0)
Interactions of vinca alkaloids with hepato-cellular methotrexate transport (1993) (0)
Drug metabolism in suspensions of isolated rat liver cells at high pressure. (1979) (0)
[Drug therapy]. (2003) (0)

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What Schools Are Affiliated With Jarle Aarbakke?

Jarle Aarbakke is affiliated with the following schools:

University of Tromsø