J. D. Ew Morrow
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J. D. Ew Morrowbiology Degrees
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Cell Biology
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Molecular Biology
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Genetics
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Biology
J. D. Ew Morrow's Degrees
- PhD Molecular Biology University of California, Berkeley
- Masters Biochemistry Stanford University
Why Is J. D. Ew Morrow Influential?
(Suggest an Edit or Addition)J. D. Ew Morrow's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Accelerated telomere shortening in response to life stress. (2004) (2771)
- Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging (2005) (1889)
- A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. (1990) (1834)
- Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage. (1995) (1434)
- Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. (1998) (1210)
- Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo. (2000) (993)
- Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. (1997) (773)
- Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. (2004) (748)
- Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids. (1992) (706)
- Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? (2005) (653)
- A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice (2008) (605)
- The Isoprostanes: Unique Bioactive Products of Lipid Peroxidation (1997) (592)
- Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. (1999) (581)
- Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. (2004) (573)
- Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors. (1992) (507)
- Factors associated with oxidative stress in human populations. (2002) (485)
- Noncyclooxygenase oxidative formation of a series of novel prostaglandins: analytical ramifications for measurement of eicosanoids. (1990) (461)
- The isoprostanes. Current knowledge and directions for future research. (1996) (453)
- Quantification of Isoprostanes as Indices of Oxidant Stress and the Risk of Atherosclerosis in Humans (2004) (448)
- Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects. (1998) (439)
- Lipid peroxidation in aging brain and Alzheimer's disease. (2002) (424)
- Formation of Isoprostane-like Compounds (Neuroprostanes) in Vivo from Docosahexaenoic Acid* (1998) (419)
- Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress. (1999) (418)
- Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester. (1994) (393)
- Metabolism of the Endocannabinoids, 2-Arachidonylglycerol and Anandamide, into Prostaglandin, Thromboxane, and Prostacyclin Glycerol Esters and Ethanolamides* (2002) (365)
- Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis. (1996) (364)
- Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells. (1997) (328)
- Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. (1992) (322)
- Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver. (1994) (321)
- Quantification of F2-isoprostanes as a biomarker of oxidative stress (2007) (307)
- Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis. (1999) (307)
- Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes. (1994) (303)
- Cyclooxygenase-2 Promotes Early Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice (2002) (301)
- The generation and actions of isoprostanes. (1997) (301)
- The sphingosine kinase 1/sphingosine‐1‐phosphate pathway mediates COX‐2 induction and PGE2 production in response to TNF‐α (2003) (300)
- F2-Isoprostanes as markers of oxidative stress in vivo: An overview (2005) (288)
- Regulation of Constitutive Cyclooxygenase-2 Expression in Colon Carcinoma Cells* (2000) (284)
- Novel n-3 Fatty Acid Oxidation Products Activate Nrf2 by Destabilizing the Association between Keap1 and Cullin3* (2007) (278)
- Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II. (2002) (275)
- Antioxidant Vitamins C and E Improve Endothelial Function in Children With Hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial (2003) (273)
- Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment (2005) (265)
- Antioxidant supplementation prevents exercise-induced lipid peroxidation, but not inflammation, in ultramarathon runners. (2004) (259)
- A Causative Role for Redox Cycling of Myoglobin and Its Inhibition by Alkalinization in the Pathogenesis and Treatment of Rhabdomyolysis-induced Renal Failure* (1998) (256)
- Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes. (1994) (253)
- Cerebrospinal fluid F2‐isoprostane levels are increased in Alzheimer's disease (1998) (253)
- Cancer-associated immunodeficiency and dendritic cell abnormalities mediated by the prostaglandin EP2 receptor. (2003) (252)
- Elevated CSF prostaglandin E2 levels in patients with probable AD. (1999) (250)
- Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. (1999) (248)
- Increased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin E. (2000) (248)
- Evidence that histamine is the causative toxin of scombroid-fish poisoning. (1991) (246)
- The isoprostanes: unique products of arachidonic acid oxidation-a review. (2003) (244)
- Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro. (1994) (243)
- The relationship between dose of vitamin E and suppression of oxidative stress in humans. (2007) (242)
- Increased CSF F2-isoprostane concentration in probable AD (1999) (241)
- Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases. (2004) (238)
- Evidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cells. (1993) (231)
- Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer. (2003) (229)
- Acetylcholine‐induced endothelium‐dependent contractions in the SHR aorta: the Janus face of prostacyclin (2005) (229)
- Mass spectrometry of prostanoids: F2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism. (1994) (227)
- The F2-isoprostane, 8-epi-prostaglandin F2 alpha, a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonist. (1992) (222)
- Selective vulnerability of preterm white matter to oxidative damage defined by F2‐isoprostanes (2005) (221)
- DASH Diet Lowers Blood Pressure and Lipid-Induced Oxidative Stress in Obesity (2003) (218)
- Enhanced in vivo lipid peroxidation at elevated plasma total homocysteine levels. (1999) (216)
- Release of markedly increased quantities of prostaglandin D2 in vivo in humans following the administration of nicotinic acid. (1989) (215)
- Antioxidant Activity of Vitamin C in Iron-overloaded Human Plasma* (1997) (208)
- THE ISOPROSTANES: THEIR QUANTIFICATION AS AN INDEX OF OXIDANT STRESS STATUS IN VIVO† (2000) (208)
- Oxidative Stress and Matrix Metalloproteinase-9 in Acute Ischemic Stroke: The Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) Study (2008) (208)
- Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans. (1992) (204)
- A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal epithelial cells. (1997) (203)
- Activation of human THP-1 cells and rat bone marrow-derived macrophages by Helicobacter pylori lipopolysaccharide (1995) (203)
- Influence of vitamin C supplementation on oxidative and immune changes after an ultramarathon. (2002) (202)
- Prostaglandin F2-like compounds, F2-isoprostanes, are present in increased amounts in human atherosclerotic lesions. (1997) (202)
- Cytosolic phospholipase A2α deficiency is crucial for 'on-time' embryo implantation that directs subsequent development (2002) (197)
- Human Biochemistry of the Isoprostane Pathway* (2008) (197)
- Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. (2005) (193)
- Products of the isoprostane pathway: unique bioactive compounds and markers of lipid peroxidation (2002) (187)
- A nomenclature system for the isoprostanes. (1997) (182)
- Linkage of hypoalbuminemia, inflammation, and oxidative stress in patients receiving maintenance hemodialysis therapy. (2003) (182)
- Pathogenesis of diquat‐induced liver necrosis in selenium‐deficient rats: Assessment of the roles of lipid peroxidation and selenoprotein P (1995) (181)
- Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study. (2004) (181)
- Quantification of F2-isoprostanes in biological fluids and tissues as a measure of oxidant stress. (2007) (180)
- Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. (1999) (175)
- Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. (2001) (175)
- Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE2 synthesis in healthy humans and those with lung cancer. (2004) (171)
- Identification of Extremely Reactive γ-Ketoaldehydes (Isolevuglandins) as Products of the Isoprostane Pathway and Characterization of Their Lysyl Protein Adducts* (1999) (170)
- Short- and Long-Term COX-2 Inhibition Reverses Endothelial Dysfunction in Patients With Hypertension (2003) (166)
- The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha. (2003) (162)
- Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription (2009) (161)
- Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. (1996) (161)
- Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite. (1995) (160)
- Meloxicam inhibits the growth of colorectal cancer cells. (1998) (160)
- Antioxidant supplementation decreases lipid peroxidation biomarker F(2)-isoprostanes in plasma of smokers. (2002) (160)
- Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors. A report of four cases. (2000) (157)
- Quantification of the major urinary metabolite of 15-F2t-isoprostane (8-iso-PGF2alpha) by a stable isotope dilution mass spectrometric assay. (1999) (157)
- Identification of non-cyclooxygenase-derived prostanoid (F2-isoprostane) metabolites in human urine and plasma. (1993) (156)
- Formation of Reactive Cyclopentenone Compounds in Vivo as Products of the Isoprostane Pathway* (1999) (156)
- Evidence that the F2-isoprostane, 8-epi-prostaglandin F2α, is formed in vivo (1994) (156)
- Identification of the Major Urinary Metabolite of the F2-isoprostane 8-Iso-prostaglandin F2α in Humans* (1996) (155)
- Colon Carcinoma Cell Growth Is Associated with Prostaglandin E2/EP4 Receptor-evoked ERK Activation* (2004) (151)
- Peripheral F2‐isoprostanes and F4‐neuroprostanes are not increased in Alzheimer's disease (2002) (151)
- Antioxidants reduce cyclooxygenase-2 expression, prostaglandin production, and proliferation in colorectal cancer cells. (1998) (150)
- Effect of Renal Transplantation on Biomarkers of Inflammation and Oxidative Stress in End-Stage Renal Disease Patients (2005) (148)
- Regulation of Prostaglandin Biosynthesis by Nitric Oxide Is Revealed by Targeted Deletion of Inducible Nitric-oxide Synthase* (2000) (146)
- The isoprostanes - unique products of arachidonate peroxidation: their role as mediators of oxidant stress. (2006) (144)
- Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation. (1997) (144)
- Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as assessed by plasma malondialdehyde and F(2)-isoprostanes. (2000) (143)
- Immune and oxidative changes during and following the Western States Endurance Run. (2003) (143)
- The isoprostanes: their role as an index of oxidant stress status in human pulmonary disease. (2002) (142)
- Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)‐α‐lipoic acid (2001) (141)
- Ibuprofen use, endotoxemia, inflammation, and plasma cytokines during ultramarathon competition (2006) (141)
- Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling. (2006) (140)
- Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice. (2002) (139)
- Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction. (2008) (138)
- Metabolism of Prostaglandin Glycerol Esters and Prostaglandin Ethanolamides in Vitro and in Vivo * (2001) (138)
- Angiotensin II Induces Interleukin-6 in Humans Through a Mineralocorticoid Receptor–Dependent Mechanism (2006) (137)
- Electrophilic Cyclopentenone Neuroprostanes Are Anti-inflammatory Mediators Formed from the Peroxidation of the ω-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid* (2008) (135)
- Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species. (2006) (135)
- Airway and vascular effects of 8-epi-prostaglandin F2 alpha in isolated perfused rat lung. (1993) (135)
- Relations of glycemic index and glycemic load with plasma oxidative stress markers. (2006) (135)
- Increased lipid peroxidation in patients with rhabdomyolysis (1999) (133)
- Vitamin E and immunity after the Kona Triathlon World Championship. (2004) (133)
- Allergen-induced synthesis of F(2)-isoprostanes in atopic asthmatics. Evidence for oxidant stress. (1999) (132)
- The isoprostanes: unique prostaglandin-like products of free-radical-initiated lipid peroxidation. (1999) (131)
- Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1). (1993) (131)
- Cyclooxygenase-2-derived Prostaglandin E2 Directs Oocyte Maturation by Differentially Influencing Multiple Signaling Pathways* (2006) (131)
- Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer. (2005) (130)
- Vitamin C suppresses oxidative lipid damage in vivo, even in the presence of iron overload. (2000) (130)
- Neuronal oxidative damage from activated innate immunity is EP2 receptor‐dependent (2002) (129)
- Effect of oxygen tension on the generation of F2-isoprostanes and malondialdehyde in peroxidizing rat liver microsomes. (1994) (126)
- Plasma F2-isoprostane levels are elevated in chronic hemodialysis patients. (2002) (126)
- Coordinated regulation of fetal and maternal prostaglandins directs successful birth and postnatal adaptation in the mouse. (2000) (126)
- Effects of a novel prostaglandin, 8-epi-PGF2 alpha, in rabbit lung in situ. (1992) (125)
- A novel mechanism for vasoconstrictor action of 8-isoprostaglandin F2α on retinal vessels. (1998) (123)
- Formation of F-ring Isoprostane-like Compounds (F3-Isoprostanes) in Vivo from Eicosapentaenoic Acid* (2006) (121)
- Targeting Cyclooxygenase-2 in Recurrent Non–Small Cell Lung Cancer: A Phase II Trial of Celecoxib and Docetaxel (2005) (121)
- The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level. (2008) (120)
- The catalytic outcomes of the constitutive and the mitogen inducible isoforms of prostaglandin H2 synthase are markedly affected by glutathione and glutathione peroxidase(s). (1995) (120)
- Identification and relative quantitation of F2-isoprostane regioisomers formed in vivo in the rat. (1997) (119)
- Prolonged exercise, lymphocyte apoptosis and F2-isoprostanes (2002) (119)
- Energy Expenditure, Inflammation, and Oxidative Stress in Steady-State Adolescents With Sickle Cell Anemia (2007) (119)
- The glyceryl ester of prostaglandin E2 mobilizes calcium and activates signal transduction in RAW264.7 cells (2004) (117)
- Oxidant stress is increased during treatment of human immunodeficiency virus infection. (2003) (116)
- The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients. (1999) (115)
- Cytosolic phospholipase A2alpha is crucial [correction of A2alpha deficiency is crucial] for 'on-time' embryo implantation that directs subsequent development. (2002) (115)
- Proteins containing non‐native disulfide bonds generated by oxidative stress can act as signals for the induction of the heat shock response (1997) (114)
- Detection and localization of lipid peroxidation in selenium- and vitamin E-deficient rats using F2-isoprostanes. (1994) (114)
- Nonenzymatic Free Radical-catalyzed Generation of Thromboxane-like Compounds (Isothromboxanes) in Vivo* (1996) (113)
- Cerebrospinal fluid F2-isoprostanes are elevated in Huntington’s disease (1999) (112)
- Rescue of Female Infertility from the Loss of Cyclooxygenase-2 by Compensatory Up-regulation of Cyclooxygenase-1 Is a Function of Genetic Makeup* (2004) (111)
- F(2)-isoprostanes mediate high glucose-induced TGF-beta synthesis and glomerular proteinuria in experimental type I diabetes. (2000) (111)
- The effect of N-acetylcysteine on renal function, nitric oxide, and oxidative stress after angiography. (2003) (109)
- Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice. (2005) (109)
- A Phase I Trial to Determine the Optimal Biological Dose of Celecoxib when Combined with Erlotinib in Advanced Non–Small Cell Lung Cancer (2006) (108)
- Prostaglandin J2 and 15-deoxy-delta12,14-prostaglandin J2 induce proliferation of cyclooxygenase-depleted colorectal cancer cells. (1999) (108)
- Levels of Prostaglandin E Metabolite and Leukotriene E4 Are Increased in the Urine of Smokers: Evidence that Celecoxib Shunts Arachidonic Acid into the 5-Lipoxygenase Pathway (2009) (108)
- Recent advances in the biochemistry and clinical relevance of the isoprostane pathway (2005) (107)
- Fatty acid oxidation in the pathogenesis of Alzheimer's disease. (2005) (107)
- Cerebrospinal Fluid Aβ42, Tau, and F2-Isoprostane Concentrations in Patients With Alzheimer Disease, Other Dementias, and in Age-Matched Controls (2001) (106)
- Peroxisome Proliferator-activated Receptor δ Activation Promotes Cell Survival following Hypertonic Stress* (2002) (105)
- Chronic quercetin ingestion and exercise-induced oxidative damage and inflammation. (2008) (103)
- Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice. (2007) (102)
- Low Sodium DASH Reduces Oxidative Stress and Improves Vascular Function in Salt-Sensitive Humans (2009) (101)
- Vitamin E ameliorates enhanced renal lipid peroxidation and accumulation of F2-isoprostanes in aging kidneys. (1998) (101)
- Marked overproduction of non-cyclooxygenase derived prostanoids (F2-isoprostanes) in the hepatorenal syndrome. (1993) (100)
- F2-isoprostanes in Alzheimer and other neurodegenerative diseases. (2005) (100)
- Effect of alpha-tocopherol supplementation on plasma homocysteine and oxidative stress in highly trained athletes before and after exhaustive exercise. (2005) (99)
- Long-term effect of combined vitamins E and C on coronary and peripheral endothelial function. (2004) (98)
- Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease (2003) (98)
- Trans‐4‐hydroxy‐2‐hexenal is a neurotoxic product of docosahexaenoic (22:6; n‐3) acid oxidation (2008) (97)
- Subpressor doses of angiotensin II increase plasma F(2)-isoprostanes in rats. (2000) (97)
- Prospective study of urinary prostaglandin E2 metabolite and colorectal cancer risk. (2006) (97)
- Hyperthermia increases exercise-induced oxidative stress. (2005) (94)
- Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2‐isoprostane, 15‐F2t‐IsoP (8‐iso‐PGF2α) (2001) (94)
- The isoprostanes: novel prostaglandin-like products of the free radical-catalyzed peroxidation of arachidonic acid. (1999) (94)
- Thioredoxin-1 modulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1alpha in non-small cell lung cancer. (2006) (94)
- Quantification of noncyclooxygenase derived prostanoids as a marker of oxidative stress. (1991) (94)
- Is oxidant stress a connection between obesity and atherosclerosis? (2003) (94)
- Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells. (2003) (93)
- Formation of Prostaglandins E2 and D2 via the Isoprostane Pathway (2003) (92)
- Cyclopentenone Isoprostanes Inhibit the Inflammatory Response in Macrophages* (2005) (92)
- Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart. (2003) (92)
- Association between low serum enterolactone and increased plasma F2-isoprostanes, a measure of lipid peroxidation. (2002) (91)
- Epidemiological marker for oxidant status: comparison of the ELISA and the gas chromatography/mass spectrometry assay for urine 2,3-dinor-5,6-dihydro-15-F2t-isoprostane. (2004) (91)
- Formation of Highly Reactive A-ring and J-ring Isoprostane-like Compounds (A4/J4-neuroprostanes) in Vivo from Docosahexaenoic Acid* (2002) (90)
- Increasing plasma fatty acids elevates F2-isoprostanes in humans: implications for the cardiovascular risk factor cluster (2002) (89)
- Differentiation of Cyclooxygenase 1- and 2–Derived Prostanoids in Mouse Kidney and Aorta (2006) (87)
- Low plasma ascorbic acid independently predicts the presence of an unstable coronary syndrome. (1998) (87)
- Effect of daily fruit ingestion on angiotensin converting enzyme activity, blood pressure, and oxidative stress in chronic smokers (2005) (86)
- Increased oxidative stress in patients with depression and its relationship to treatment (2013) (85)
- Oxidative stress in systemic lupus erythematosus: relationship to disease activity and symptoms (2007) (85)
- Metabolism of bradykinin In vivo in humans: identification of BK1-5 as a stable plasma peptide metabolite. (2000) (85)
- Actions of the E2-isoprostane, 8-ISO-PGE2, on the platelet thromboxane/endoperoxide receptor in humans and rats: additional evidence for the existence of a unique isoprostane receptor. (1994) (85)
- Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. (2006) (83)
- Oxidative stress measured by urine F2-isoprostane level is associated with prostate cancer. (2011) (82)
- Lack of Integrin α1β1 Leads to Severe Glomerulosclerosis after Glomerular Injury (2004) (81)
- Quantification of F2-isoprostanes as a reliable index of oxidative stress in vivo using gas chromatography-mass spectrometry (GC-MS) method. (2009) (81)
- Formation of novel D-ring and E-ring isoprostane-like compounds (D4/E4-neuroprostanes) in vivo from docosahexaenoic acid. (2000) (81)
- Comparison of formation of D2/E2-isoprostanes and F2-isoprostanes in vitro and in vivo--effects of oxygen tension and glutathione. (1998) (80)
- Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells. (1999) (80)
- Isoprostanes. Novel markers of endogenous lipid peroxidation and potential mediators of oxidant injury. (1994) (80)
- Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration (2006) (79)
- Development of Oxidative Stress by Cytochrome P450 Induction in Rodents Is Selective for Barbiturates and Related to Loss of Pyridine Nucleotide-dependent Protective Systems* (2008) (79)
- A Phase II Study of Celecoxib in Combination with Paclitaxel, Carboplatin, and Radiotherapy for Patients with Inoperable Stage IIIA/B Non–Small Cell Lung Cancer (2009) (79)
- Vitamin C Supplementation Decreases Oxidative Stress Biomarker F2-Isoprostanes in Plasma of Nonsmokers Exposed to Environmental Tobacco Smoke (2003) (79)
- Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A3/J3-Isoprostanes) in Vivo from Eicosapentaenoic Acid* (2008) (79)
- Interaction of ascorbate and alpha-tocopherol in resealed human erythrocyte ghosts. Transmembrane electron transfer and protection from lipid peroxidation. (1996) (79)
- Inhibition of Mesangial Cell Nitric Oxide in MRL/lpr Mice by Prostaglandin J2 and Proliferator Activation Receptor-γ Agonists1 (2000) (77)
- Supplementation with orange and blackcurrant juice, but not vitamin E, improves inflammatory markers in patients with peripheral arterial disease (2008) (77)
- Diisopropylphosphorofluoridate-induced muscle hyperactivity associated with enhanced lipid peroxidation in vivo. (1996) (76)
- Quantification of F-ring isoprostane-like compounds (F4-neuroprostanes) derived from docosahexaenoic acid in vivo in humans by a stable isotope dilution mass spectrometric assay. (2004) (76)
- Urinary Prostaglandin F2α Is Generated from the Isoprostane Pathway and Not the Cyclooxygenase in Humans* (2007) (75)
- Contribution of Cyclooxygenase-2 to Elevated Biosynthesis of Thromboxane A2 and Prostacyclin in Cigarette Smokers (2005) (75)
- Mechanisms of ascorbic acid recycling in human erythrocytes. (2001) (75)
- Influence of vitamin C supplementation on oxidative and salivary IgA changes following an ultramarathon (2003) (74)
- Characterization of LPS-induced lung inflammation in cftr-/- mice and the effect of docosahexaenoic acid. (2002) (74)
- Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimer's disease. (2004) (73)
- Zinc deficiency increases plasma lipids and atherosclerotic markers in LDL-receptor-deficient mice. (2005) (73)
- Cyclosporine A suppresses keratinocyte cell death through MPTP inhibition in a model for skin cancer in organ transplant recipients. (2010) (71)
- Oral quercetin supplementation and blood oxidative capacity in response to ultramarathon competition. (2008) (69)
- ISOPROSTANES—RROSTAGLANDIN-LIKE COMPOUNDS FORMED IN VIVO INDEPENDENTLY OF CYCLOOXYGENASE (1996) (67)
- COX-2 compensation in the uterus of COX-1 deficient mice during the pre-implantation period (1999) (66)
- Intraindividual Variability of Plasma Antioxidants, Markers of Oxidative Stress, C-Reactive Protein, Cotinine, and Other Biomarkers (2006) (64)
- Regiochemistry of Neuroprostanes Generated from the Peroxidation of Docosahexaenoic Acid in Vitro and in Vivo* (2005) (64)
- Cell proliferation and apoptotic indices predict adenoma regression in a placebo-controlled trial of celecoxib in familial adenomatous polyposis patients. (2004) (63)
- Increased levels of F2-isoprostanes following aneurysmal subarachnoid hemorrhage in humans. (2006) (63)
- Levels of Prostaglandin E Metabolite, the Major Urinary Metabolite of Prostaglandin E2, Are Increased in Smokers (2005) (62)
- Increased dietary NaCl induces renal medullary PGE2 production and natriuresis via the EP2 receptor. (2008) (62)
- Formation of isoprostane bicyclic endoperoxides from the autoxidation of cholesteryl arachidonate. (2002) (61)
- Effect of resistance exercise and carbohydrate ingestion on oxidative stress (2005) (61)
- Cyclopentenone Eicosanoids as Mediators of Neurodegeneration: A Pathogenic Mechanism of Oxidative Stress‐Mediated and Cyclooxygenase‐Mediated Neurotoxicity (2005) (61)
- Nitric oxide synthesis and isoprostane production in subjects with type 1 diabetes and normal urinary albumin excretion. (2000) (61)
- Consumption of blueberry polyphenols reduces exercise-induced oxidative stress compared to vitamin C (2004) (61)
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- Quantification of Isoprostanes as an Index of Oxidant Stress Status In Vivo (2002) (1)
- Urine PGE-M to assess prostaglandin E2 (PGE2) levels in non-small cell lung cancer (NSCLC). (2009) (1)
- A Phase II Study of Celecoxib in Combination With Paclitaxel, Carboplatin, and Radiation Therapy for Patients With Inoperable Stage IIIA/B Non-Small Cell Lung Cancer (2007) (1)
- Fulminant Kaposi's sarcoma without mucocutaneous disease. (2003) (1)
- Development of immunoassays for 5,6-, 8,9- 11,12-, and 14-15 epoxyeicosatrienoic acids (EETs) and corresponding dihydroxyeicosatrienoic acids (DHETs) (1999) (1)
- Correction: A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice (2008) (1)
- Biology and Chemistry of Products of the Isoprostane Pathway (2004) (0)
- Cerebrospinal fluid levels of F2‐isoprostanes in patients with neurodegenerative diseases (1999) (0)
- COMMENTS ON PROSTAGLANDIN F2ALPHA RISES IN RESPONSE TO HYDROXYL RADICAL GENERATED IN VIVO. AUTHOR'S REPLY (1995) (0)
- Vanderbilt morning report. A case of syncope. (1998) (0)
- EFFECT OF EXERCISE AND HYPERTHERMIA ON INDICES OF OXIDATIVE STRESS (2001) (0)
- NON-ENZYMATIC OMEGA-3-FATTY ACID BREAK-DOWN PRODUCTS ARE DIFFERENTIALLY EXPRESSED IN RHEUMATOID ARTHRITIS AND SUPPRESS NFKB ACTIVITY TO INHIBIT OSTEOCLAST FORMATION (2012) (0)
- Abstract 10544: Cocoa Increases Plasma Epicatechin Concentrations in Hyperlipidemic Children Without Adverse Effects on the Lipid Profile or Markers of Oxidative Stress (2011) (0)
- Formation and Metabolism of 15-Deoxy-Δ12,14Prostaglandin J2 (2010) (0)
- Detection of lipid peroxidation in vivo in selenium and vitamin E deficiency (1993) (0)
- Comments on prostaglandin F2 alpha rises in response to hydroxyl radical generated in vivo. (1995) (0)
- A case of pneumococcal meningitis. (2000) (0)
- APhase II Study of Celecoxib in Combinationwith Paclitaxel, Carboplatin, and Radiotherapy for Patients with Inoperable Stage IIIA/BNon^Small Cell Lung Cancer (2009) (0)
- Inhibition of F2-isoprostane synthesis reduces proteinuria and improves renal function in streptozotocin (STZ)-induced diabetic rats (1999) (0)
- DOES ASCORBIC ACID AND FREE IRON IN PLASMA OF PRETERM INFANTS CAUSE OXIDATIVE DAMAGE? † 1156 (1996) (0)
- Development of a competititve immunometric enzyme-linked immunosorbent assay (ELISA) for the major human urinary metabolite of 15-F2T-isoprostane, a noninvasive biomarker for oxidant stress (1999) (0)
- PII‐5 (2006) (0)
- Reply (2003) (0)
- Constitutively activated MEK1 represses sodium butyrate induced cell differentiation and apoptosis in rat intestinal epithelial cells (2003) (0)
- vasculature of healthy mice -dependent iNOS expression in the γ suppressing bacteria and IFN Circulating neutrophils maintain physiological blood pressure by (2013) (0)
- Assessment of oxidative stress in the rat model of chronic dietary iron overload (IO) (1993) (0)
- Augmentation of allergic inflammation by cyclooxygenase inhibition is not dependent on IL-4 (2002) (0)
- PPARγ and β-catenin interact to regulate COX-2 expression induced by insulin in HT-29 colon cancer cells (2001) (0)
- A case of alcoholic ketoacidosis. (1987) (0)
- Phase II study of the clinical and biological activity of cetuximab and celecoxib in patients (pts) with refractory colorectal cancer (CRC) (2007) (0)
- Role of short-term α-lipoic acid therapy in patients with hypercholesterolemia to reverse oxidative stress and endothelial dysfunction (2015) (0)
- O'Neill, Onora. Autonomy and Trust in Bioethics (2003) (0)
- Correction: Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the ω -3 polyunsaturated fatty acid docosahexaenoic acid. (2019) (0)
- Why Markets in Human Organs Should be Legalized (2013) (0)
- A man with a large abdominal mass. (1988) (0)
- PII‐14 (2006) (0)
- A case of typhoid fever. (1988) (0)
- Oral ulcerations in a patient with sarcoidosis. (1999) (0)
- Smad4 independent induction of COX-2 by transforming growth factor-B1 (TGF-B1) in human pancreatic carcinoma (BXPC-3) cells (2000) (0)
- Lipid peroxidation: from basic mechanisms to clinical relevance (2007) (0)
- depletion in exercising and nonexercising hamsters Ozone causes lipid peroxidation but little antioxidant (2015) (0)
- A young man with meningitis and purpura. (1988) (0)
- Pancytopenia in an elderly woman. (1988) (0)
- A Phase I Study of Neoadjuvant Cyclooxygenase-2 Inhibition and Chemoradiation for Stage II/III Rectal Cancer (2007) (0)
- Comparative evaluation of measuring Tbars and F2-isoprostanes in the assessment of lipid peroxidation in vitro and in vivo (1993) (0)
- Comments on prostaglandin F2α rises in response to hydroxyl radical generated in vivo (1995) (0)
- Non-Cyclooxygenase Oxidative Formation of a Series of Novel Prostaglandins: Ramifications for the Measurement of Eicosanoids in Biological Fluids (1990) (0)
- EFFECT OF CIMETIDINE ON LIPID PEROXIDATION IN THE LUNGS OF PREMATURE NEWBORN INFANTS. † 1956 (1996) (0)
- receptor 2 signaling induces COX-2 expression in Wilms tumor (2014) (0)
- Reactive Products of the Isoprostane Pathway: Isoketals and Cyclopentenone A2/J2-Isoprostanes (2001) (0)
- STAT6-Independent Mechanisms Inflammation through CD4-Dependent, Cyclooxygenase Inhibition Augments Allergic (2013) (0)
- O.19 Pro- or antioxidant activity of ascorbic acid in thepresence of ‘free’ iron in plasma of preterm infants? (1996) (0)
- Development of an accurate method to quantify F4-neuroprostanes in vivo in humans (2002) (0)
- Comparison of Enzyme Immunoassays with Gas Chromatography -Isoprostanes as Markers of in Vivo Lipid Peroxidation: A 2 Measurement of Urinary F (2015) (0)
- Eicosanoids in non-small cell lung cancer (NSCLC). (2010) (0)
- Abstract B85: Comparison of three oxidative stress biomarkers in a sample of healthy adults (2008) (0)
- Formation of free radical-derived F2-isoprostanes in human plasma and LDL (1993) (0)
- 7The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells (2005) (0)
- Herpes simplex virus type 1 ( HSV-1 ) is an important pathogen infecting the vast majority of humans (2005) (0)
- Augmentation of allergic inflammation by cyclooxygenase (COX) inhibition does not depend on STAT6 signaling (2003) (0)
- Cancer Small Cell Lung − in Non α via Hypoxia-Inducible Factor-1 Thioredoxin-1 Modulates Transcription of Cyclooxygenase-2 Updated (2005) (0)
- Preliminary results of a phase II study of cyclooxygenase-2 (COX-2) inhibition in rectal cancer (2004) (0)
- Vanderbilt morning report. A case of alcoholic ketoacidosis. (1998) (0)
- Biliary obstruction induces an oxidant injury in the rat small intestine (2001) (0)
- Cyclooxygenase (COX) inhibition at the time of initial antigen presentation results in enhanced IL-13 and IgE (2003) (0)
- Splicing mutation of the prostacyclin synthase gene in a family associated with hypertension. (2004) (0)
- 2045 THE ASSOCIATION BETWEEN OXIDATIVE STRESS AND PROSTATE CANCER RISK IN MEN UNDERGOING PROSTATE BIOPSY (2010) (0)
- -prostaglandin J2 Induce Proliferation of Cyclooxygenase-depleted Colorectal Cancer Cells (2000) (0)
- PII‐10 (2006) (0)
- Transforming growth factor-β1 (TGF-β1) induces cyclooxygenase-2 and prostaglandin E2 synthesis in human colon adenoma cells (1998) (0)
- Oxidant stress in the pathogenesis of the hepatorenal syndrome (1993) (0)
- W1146 Novel Biomarkers of Ulcerative Colitis Activity: A Comparison of Urinary PGE-M, Fecal Calprotectin and C- Reactive Protein (CRP) Levels (2008) (0)
- Isoprostane levels are altered in rheumatoid arthritis and suppress NFκB activity to inhibit osteoclast formation (2011) (0)
- The Antiangiogenic Agent SU 5416 Down-Regulates Phorbol Ester-Mediated Induction of Cyclooxygenase 2 Expression by Inhibiting Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activity 1 (2003) (0)
- A CASE OF SYNCOPE (1998) (0)
- INFLUENCE OF VITAMIN C SUPPLEMENTATION ON SALIVARY IGA CHANGES FOLLOWING AN ULTRAMARATHON (2002) (0)
- Pancreatic enzyme replacement therapy. (1989) (0)
- 7 FIRST DESCRIPTION: CYTOSOLIC PHOSPHOLIPASE A2-a DEFICIENCY. (2006) (0)
- Dependent on 5-Lipoxygenase or IL-5 , but Is IL-13 Cyclooxygenase Inhibition Is Not Dependent Hyperresponsiveness Mediated by Allergen-Induced Airway (2005) (0)
- Carbohydrate Ingestion, Oxidative Stress, and Plasma Antioxidant Potential Following Intensive Resistance Training (2004) (0)
- Urine PGE-M as a marker of intratumoral cyclooxygenase-2 activity in non-small cell lung cancer (NSCLC). (2004) (0)
- Effect of Blueberry Ingestion on Oxidative Stress and Plasma Antioxidant Potential Following a 2.5 Hour Run (2004) (0)
- Influence Of Carbohydrate/placebo On Oxidative Changes And Plasma Antioxidant Capacity Following 2.5-hours Of Intensive Cycling: 2301 Board #90 10:30AM ??? 12:00PM (2005) (0)
- Induction of COX-2 and invasiveness by transforming growth factor-β1 in immortalized mouse colonocytes expressing oncogenic ras (2001) (0)
- Prostaglandin production is significantly decreased in mice deficient in inducible nitric oxide synthase (1999) (0)
- PII‐11 (2006) (0)
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