J. D. Ew Morrow

Q: What Schools Are Affiliated With J. D. Ew Morrow

J. D. Ew Morrow is affiliated with the following schools: Uppsala University, Emory University, University of Tokyo, Appalachian State University, University of Florida, University of Pavia, Vanderbilt University, Cardiff University

J. D. Ew Morrow's AcademicInfluence.com Rankings

J. D. Ew Morrow

Biology

#4906

World Rank

#7254

Historical Rank

Cell Biology

#128

World Rank

#133

Historical Rank

Molecular Biology

#406

World Rank

#414

Historical Rank

Genetics

#428

World Rank

#494

Historical Rank

biology Degrees

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Biology

J. D. Ew Morrow's Degrees

PhD Molecular Biology University of California, Berkeley
Masters Biochemistry Stanford University

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J. D. Ew Morrow's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Accelerated telomere shortening in response to life stress. (2004) (2771)
Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging (2005) (1889)
A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. (1990) (1834)
Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage. (1995) (1434)
Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. (1998) (1210)
Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo. (2000) (993)
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. (1997) (773)
Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. (2004) (748)
Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids. (1992) (706)
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? (2005) (653)
A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice (2008) (605)
The Isoprostanes: Unique Bioactive Products of Lipid Peroxidation (1997) (592)
Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. (1999) (581)
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. (2004) (573)
Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors. (1992) (507)
Factors associated with oxidative stress in human populations. (2002) (485)
Noncyclooxygenase oxidative formation of a series of novel prostaglandins: analytical ramifications for measurement of eicosanoids. (1990) (461)
The isoprostanes. Current knowledge and directions for future research. (1996) (453)
Quantification of Isoprostanes as Indices of Oxidant Stress and the Risk of Atherosclerosis in Humans (2004) (448)
Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects. (1998) (439)
Lipid peroxidation in aging brain and Alzheimer's disease. (2002) (424)
Formation of Isoprostane-like Compounds (Neuroprostanes) in Vivo from Docosahexaenoic Acid* (1998) (419)
Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress. (1999) (418)
Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester. (1994) (393)
Metabolism of the Endocannabinoids, 2-Arachidonylglycerol and Anandamide, into Prostaglandin, Thromboxane, and Prostacyclin Glycerol Esters and Ethanolamides* (2002) (365)
Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis. (1996) (364)
Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells. (1997) (328)
Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. (1992) (322)
Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver. (1994) (321)
Quantification of F2-isoprostanes as a biomarker of oxidative stress (2007) (307)
Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis. (1999) (307)
Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes. (1994) (303)
Cyclooxygenase-2 Promotes Early Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice (2002) (301)
The generation and actions of isoprostanes. (1997) (301)
The sphingosine kinase 1/sphingosine‐1‐phosphate pathway mediates COX‐2 induction and PGE2 production in response to TNF‐α (2003) (300)
F2-Isoprostanes as markers of oxidative stress in vivo: An overview (2005) (288)
Regulation of Constitutive Cyclooxygenase-2 Expression in Colon Carcinoma Cells* (2000) (284)
Novel n-3 Fatty Acid Oxidation Products Activate Nrf2 by Destabilizing the Association between Keap1 and Cullin3* (2007) (278)
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II. (2002) (275)
Antioxidant Vitamins C and E Improve Endothelial Function in Children With Hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial (2003) (273)
Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment (2005) (265)
Antioxidant supplementation prevents exercise-induced lipid peroxidation, but not inflammation, in ultramarathon runners. (2004) (259)
A Causative Role for Redox Cycling of Myoglobin and Its Inhibition by Alkalinization in the Pathogenesis and Treatment of Rhabdomyolysis-induced Renal Failure* (1998) (256)
Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes. (1994) (253)
Cerebrospinal fluid F2‐isoprostane levels are increased in Alzheimer's disease (1998) (253)
Cancer-associated immunodeficiency and dendritic cell abnormalities mediated by the prostaglandin EP2 receptor. (2003) (252)
Elevated CSF prostaglandin E2 levels in patients with probable AD. (1999) (250)
Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. (1999) (248)
Increased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin E. (2000) (248)
Evidence that histamine is the causative toxin of scombroid-fish poisoning. (1991) (246)
The isoprostanes: unique products of arachidonic acid oxidation-a review. (2003) (244)
Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro. (1994) (243)
The relationship between dose of vitamin E and suppression of oxidative stress in humans. (2007) (242)
Increased CSF F2-isoprostane concentration in probable AD (1999) (241)
Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases. (2004) (238)
Evidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cells. (1993) (231)
Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer. (2003) (229)
Acetylcholine‐induced endothelium‐dependent contractions in the SHR aorta: the Janus face of prostacyclin (2005) (229)
Mass spectrometry of prostanoids: F2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism. (1994) (227)
The F2-isoprostane, 8-epi-prostaglandin F2 alpha, a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonist. (1992) (222)
Selective vulnerability of preterm white matter to oxidative damage defined by F2‐isoprostanes (2005) (221)
DASH Diet Lowers Blood Pressure and Lipid-Induced Oxidative Stress in Obesity (2003) (218)
Enhanced in vivo lipid peroxidation at elevated plasma total homocysteine levels. (1999) (216)
Release of markedly increased quantities of prostaglandin D2 in vivo in humans following the administration of nicotinic acid. (1989) (215)
Antioxidant Activity of Vitamin C in Iron-overloaded Human Plasma* (1997) (208)
THE ISOPROSTANES: THEIR QUANTIFICATION AS AN INDEX OF OXIDANT STRESS STATUS IN VIVO† (2000) (208)
Oxidative Stress and Matrix Metalloproteinase-9 in Acute Ischemic Stroke: The Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) Study (2008) (208)
Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans. (1992) (204)
A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal epithelial cells. (1997) (203)
Activation of human THP-1 cells and rat bone marrow-derived macrophages by Helicobacter pylori lipopolysaccharide (1995) (203)
Influence of vitamin C supplementation on oxidative and immune changes after an ultramarathon. (2002) (202)
Prostaglandin F2-like compounds, F2-isoprostanes, are present in increased amounts in human atherosclerotic lesions. (1997) (202)
Cytosolic phospholipase A2α deficiency is crucial for 'on-time' embryo implantation that directs subsequent development (2002) (197)
Human Biochemistry of the Isoprostane Pathway* (2008) (197)
Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. (2005) (193)
Products of the isoprostane pathway: unique bioactive compounds and markers of lipid peroxidation (2002) (187)
A nomenclature system for the isoprostanes. (1997) (182)
Linkage of hypoalbuminemia, inflammation, and oxidative stress in patients receiving maintenance hemodialysis therapy. (2003) (182)
Pathogenesis of diquat‐induced liver necrosis in selenium‐deficient rats: Assessment of the roles of lipid peroxidation and selenoprotein P (1995) (181)
Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study. (2004) (181)
Quantification of F2-isoprostanes in biological fluids and tissues as a measure of oxidant stress. (2007) (180)
Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. (1999) (175)
Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. (2001) (175)
Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE2 synthesis in healthy humans and those with lung cancer. (2004) (171)
Identification of Extremely Reactive γ-Ketoaldehydes (Isolevuglandins) as Products of the Isoprostane Pathway and Characterization of Their Lysyl Protein Adducts* (1999) (170)
Short- and Long-Term COX-2 Inhibition Reverses Endothelial Dysfunction in Patients With Hypertension (2003) (166)
The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha. (2003) (162)
Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription (2009) (161)
Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. (1996) (161)
Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite. (1995) (160)
Meloxicam inhibits the growth of colorectal cancer cells. (1998) (160)
Antioxidant supplementation decreases lipid peroxidation biomarker F(2)-isoprostanes in plasma of smokers. (2002) (160)
Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors. A report of four cases. (2000) (157)
Quantification of the major urinary metabolite of 15-F2t-isoprostane (8-iso-PGF2alpha) by a stable isotope dilution mass spectrometric assay. (1999) (157)
Identification of non-cyclooxygenase-derived prostanoid (F2-isoprostane) metabolites in human urine and plasma. (1993) (156)
Formation of Reactive Cyclopentenone Compounds in Vivo as Products of the Isoprostane Pathway* (1999) (156)
Evidence that the F2-isoprostane, 8-epi-prostaglandin F2α, is formed in vivo (1994) (156)
Identification of the Major Urinary Metabolite of the F2-isoprostane 8-Iso-prostaglandin F2α in Humans* (1996) (155)
Colon Carcinoma Cell Growth Is Associated with Prostaglandin E2/EP4 Receptor-evoked ERK Activation* (2004) (151)
Peripheral F2‐isoprostanes and F4‐neuroprostanes are not increased in Alzheimer's disease (2002) (151)
Antioxidants reduce cyclooxygenase-2 expression, prostaglandin production, and proliferation in colorectal cancer cells. (1998) (150)
Effect of Renal Transplantation on Biomarkers of Inflammation and Oxidative Stress in End-Stage Renal Disease Patients (2005) (148)
Regulation of Prostaglandin Biosynthesis by Nitric Oxide Is Revealed by Targeted Deletion of Inducible Nitric-oxide Synthase* (2000) (146)
The isoprostanes - unique products of arachidonate peroxidation: their role as mediators of oxidant stress. (2006) (144)
Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation. (1997) (144)
Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as assessed by plasma malondialdehyde and F(2)-isoprostanes. (2000) (143)
Immune and oxidative changes during and following the Western States Endurance Run. (2003) (143)
The isoprostanes: their role as an index of oxidant stress status in human pulmonary disease. (2002) (142)
Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)‐α‐lipoic acid (2001) (141)
Ibuprofen use, endotoxemia, inflammation, and plasma cytokines during ultramarathon competition (2006) (141)
Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling. (2006) (140)
Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice. (2002) (139)
Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction. (2008) (138)
Metabolism of Prostaglandin Glycerol Esters and Prostaglandin Ethanolamides in Vitro and in Vivo * (2001) (138)
Angiotensin II Induces Interleukin-6 in Humans Through a Mineralocorticoid Receptor–Dependent Mechanism (2006) (137)
Electrophilic Cyclopentenone Neuroprostanes Are Anti-inflammatory Mediators Formed from the Peroxidation of the ω-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid* (2008) (135)
Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species. (2006) (135)
Airway and vascular effects of 8-epi-prostaglandin F2 alpha in isolated perfused rat lung. (1993) (135)
Relations of glycemic index and glycemic load with plasma oxidative stress markers. (2006) (135)
Increased lipid peroxidation in patients with rhabdomyolysis (1999) (133)
Vitamin E and immunity after the Kona Triathlon World Championship. (2004) (133)
Allergen-induced synthesis of F(2)-isoprostanes in atopic asthmatics. Evidence for oxidant stress. (1999) (132)
The isoprostanes: unique prostaglandin-like products of free-radical-initiated lipid peroxidation. (1999) (131)
Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1). (1993) (131)
Cyclooxygenase-2-derived Prostaglandin E2 Directs Oocyte Maturation by Differentially Influencing Multiple Signaling Pathways* (2006) (131)
Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer. (2005) (130)
Vitamin C suppresses oxidative lipid damage in vivo, even in the presence of iron overload. (2000) (130)
Neuronal oxidative damage from activated innate immunity is EP2 receptor‐dependent (2002) (129)
Effect of oxygen tension on the generation of F2-isoprostanes and malondialdehyde in peroxidizing rat liver microsomes. (1994) (126)
Plasma F2-isoprostane levels are elevated in chronic hemodialysis patients. (2002) (126)
Coordinated regulation of fetal and maternal prostaglandins directs successful birth and postnatal adaptation in the mouse. (2000) (126)
Effects of a novel prostaglandin, 8-epi-PGF2 alpha, in rabbit lung in situ. (1992) (125)
A novel mechanism for vasoconstrictor action of 8-isoprostaglandin F2α on retinal vessels. (1998) (123)
Formation of F-ring Isoprostane-like Compounds (F3-Isoprostanes) in Vivo from Eicosapentaenoic Acid* (2006) (121)
Targeting Cyclooxygenase-2 in Recurrent Non–Small Cell Lung Cancer: A Phase II Trial of Celecoxib and Docetaxel (2005) (121)
The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level. (2008) (120)
The catalytic outcomes of the constitutive and the mitogen inducible isoforms of prostaglandin H2 synthase are markedly affected by glutathione and glutathione peroxidase(s). (1995) (120)
Identification and relative quantitation of F2-isoprostane regioisomers formed in vivo in the rat. (1997) (119)
Prolonged exercise, lymphocyte apoptosis and F2-isoprostanes (2002) (119)
Energy Expenditure, Inflammation, and Oxidative Stress in Steady-State Adolescents With Sickle Cell Anemia (2007) (119)
The glyceryl ester of prostaglandin E2 mobilizes calcium and activates signal transduction in RAW264.7 cells (2004) (117)
Oxidant stress is increased during treatment of human immunodeficiency virus infection. (2003) (116)
The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients. (1999) (115)
Cytosolic phospholipase A2alpha is crucial [correction of A2alpha deficiency is crucial] for 'on-time' embryo implantation that directs subsequent development. (2002) (115)
Proteins containing non‐native disulfide bonds generated by oxidative stress can act as signals for the induction of the heat shock response (1997) (114)
Detection and localization of lipid peroxidation in selenium- and vitamin E-deficient rats using F2-isoprostanes. (1994) (114)
Nonenzymatic Free Radical-catalyzed Generation of Thromboxane-like Compounds (Isothromboxanes) in Vivo* (1996) (113)
Cerebrospinal fluid F2-isoprostanes are elevated in Huntington’s disease (1999) (112)
Rescue of Female Infertility from the Loss of Cyclooxygenase-2 by Compensatory Up-regulation of Cyclooxygenase-1 Is a Function of Genetic Makeup* (2004) (111)
F(2)-isoprostanes mediate high glucose-induced TGF-beta synthesis and glomerular proteinuria in experimental type I diabetes. (2000) (111)
The effect of N-acetylcysteine on renal function, nitric oxide, and oxidative stress after angiography. (2003) (109)
Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice. (2005) (109)
A Phase I Trial to Determine the Optimal Biological Dose of Celecoxib when Combined with Erlotinib in Advanced Non–Small Cell Lung Cancer (2006) (108)
Prostaglandin J2 and 15-deoxy-delta12,14-prostaglandin J2 induce proliferation of cyclooxygenase-depleted colorectal cancer cells. (1999) (108)
Levels of Prostaglandin E Metabolite and Leukotriene E4 Are Increased in the Urine of Smokers: Evidence that Celecoxib Shunts Arachidonic Acid into the 5-Lipoxygenase Pathway (2009) (108)
Recent advances in the biochemistry and clinical relevance of the isoprostane pathway (2005) (107)
Fatty acid oxidation in the pathogenesis of Alzheimer's disease. (2005) (107)
Cerebrospinal Fluid Aβ42, Tau, and F2-Isoprostane Concentrations in Patients With Alzheimer Disease, Other Dementias, and in Age-Matched Controls (2001) (106)
Peroxisome Proliferator-activated Receptor δ Activation Promotes Cell Survival following Hypertonic Stress* (2002) (105)
Chronic quercetin ingestion and exercise-induced oxidative damage and inflammation. (2008) (103)
Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice. (2007) (102)
Low Sodium DASH Reduces Oxidative Stress and Improves Vascular Function in Salt-Sensitive Humans (2009) (101)
Vitamin E ameliorates enhanced renal lipid peroxidation and accumulation of F2-isoprostanes in aging kidneys. (1998) (101)
Marked overproduction of non-cyclooxygenase derived prostanoids (F2-isoprostanes) in the hepatorenal syndrome. (1993) (100)
F2-isoprostanes in Alzheimer and other neurodegenerative diseases. (2005) (100)
Effect of alpha-tocopherol supplementation on plasma homocysteine and oxidative stress in highly trained athletes before and after exhaustive exercise. (2005) (99)
Long-term effect of combined vitamins E and C on coronary and peripheral endothelial function. (2004) (98)
Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease (2003) (98)
Trans‐4‐hydroxy‐2‐hexenal is a neurotoxic product of docosahexaenoic (22:6; n‐3) acid oxidation (2008) (97)
Subpressor doses of angiotensin II increase plasma F(2)-isoprostanes in rats. (2000) (97)
Prospective study of urinary prostaglandin E2 metabolite and colorectal cancer risk. (2006) (97)
Hyperthermia increases exercise-induced oxidative stress. (2005) (94)
Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2‐isoprostane, 15‐F2t‐IsoP (8‐iso‐PGF2α) (2001) (94)
The isoprostanes: novel prostaglandin-like products of the free radical-catalyzed peroxidation of arachidonic acid. (1999) (94)
Thioredoxin-1 modulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1alpha in non-small cell lung cancer. (2006) (94)
Quantification of noncyclooxygenase derived prostanoids as a marker of oxidative stress. (1991) (94)
Is oxidant stress a connection between obesity and atherosclerosis? (2003) (94)
Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells. (2003) (93)
Formation of Prostaglandins E2 and D2 via the Isoprostane Pathway (2003) (92)
Cyclopentenone Isoprostanes Inhibit the Inflammatory Response in Macrophages* (2005) (92)
Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart. (2003) (92)
Association between low serum enterolactone and increased plasma F2-isoprostanes, a measure of lipid peroxidation. (2002) (91)
Epidemiological marker for oxidant status: comparison of the ELISA and the gas chromatography/mass spectrometry assay for urine 2,3-dinor-5,6-dihydro-15-F2t-isoprostane. (2004) (91)
Formation of Highly Reactive A-ring and J-ring Isoprostane-like Compounds (A4/J4-neuroprostanes) in Vivo from Docosahexaenoic Acid* (2002) (90)
Increasing plasma fatty acids elevates F2-isoprostanes in humans: implications for the cardiovascular risk factor cluster (2002) (89)
Differentiation of Cyclooxygenase 1- and 2–Derived Prostanoids in Mouse Kidney and Aorta (2006) (87)
Low plasma ascorbic acid independently predicts the presence of an unstable coronary syndrome. (1998) (87)
Effect of daily fruit ingestion on angiotensin converting enzyme activity, blood pressure, and oxidative stress in chronic smokers (2005) (86)
Increased oxidative stress in patients with depression and its relationship to treatment (2013) (85)
Oxidative stress in systemic lupus erythematosus: relationship to disease activity and symptoms (2007) (85)
Metabolism of bradykinin In vivo in humans: identification of BK1-5 as a stable plasma peptide metabolite. (2000) (85)
Actions of the E2-isoprostane, 8-ISO-PGE2, on the platelet thromboxane/endoperoxide receptor in humans and rats: additional evidence for the existence of a unique isoprostane receptor. (1994) (85)
Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. (2006) (83)
Oxidative stress measured by urine F2-isoprostane level is associated with prostate cancer. (2011) (82)
Lack of Integrin α1β1 Leads to Severe Glomerulosclerosis after Glomerular Injury (2004) (81)
Quantification of F2-isoprostanes as a reliable index of oxidative stress in vivo using gas chromatography-mass spectrometry (GC-MS) method. (2009) (81)
Formation of novel D-ring and E-ring isoprostane-like compounds (D4/E4-neuroprostanes) in vivo from docosahexaenoic acid. (2000) (81)
Comparison of formation of D2/E2-isoprostanes and F2-isoprostanes in vitro and in vivo--effects of oxygen tension and glutathione. (1998) (80)
Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells. (1999) (80)
Isoprostanes. Novel markers of endogenous lipid peroxidation and potential mediators of oxidant injury. (1994) (80)
Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration (2006) (79)
Development of Oxidative Stress by Cytochrome P450 Induction in Rodents Is Selective for Barbiturates and Related to Loss of Pyridine Nucleotide-dependent Protective Systems* (2008) (79)
A Phase II Study of Celecoxib in Combination with Paclitaxel, Carboplatin, and Radiotherapy for Patients with Inoperable Stage IIIA/B Non–Small Cell Lung Cancer (2009) (79)
Vitamin C Supplementation Decreases Oxidative Stress Biomarker F2-Isoprostanes in Plasma of Nonsmokers Exposed to Environmental Tobacco Smoke (2003) (79)
Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A3/J3-Isoprostanes) in Vivo from Eicosapentaenoic Acid* (2008) (79)
Interaction of ascorbate and alpha-tocopherol in resealed human erythrocyte ghosts. Transmembrane electron transfer and protection from lipid peroxidation. (1996) (79)
Inhibition of Mesangial Cell Nitric Oxide in MRL/lpr Mice by Prostaglandin J2 and Proliferator Activation Receptor-γ Agonists1 (2000) (77)
Supplementation with orange and blackcurrant juice, but not vitamin E, improves inflammatory markers in patients with peripheral arterial disease (2008) (77)
Diisopropylphosphorofluoridate-induced muscle hyperactivity associated with enhanced lipid peroxidation in vivo. (1996) (76)
Quantification of F-ring isoprostane-like compounds (F4-neuroprostanes) derived from docosahexaenoic acid in vivo in humans by a stable isotope dilution mass spectrometric assay. (2004) (76)
Urinary Prostaglandin F2α Is Generated from the Isoprostane Pathway and Not the Cyclooxygenase in Humans* (2007) (75)
Contribution of Cyclooxygenase-2 to Elevated Biosynthesis of Thromboxane A2 and Prostacyclin in Cigarette Smokers (2005) (75)
Mechanisms of ascorbic acid recycling in human erythrocytes. (2001) (75)
Influence of vitamin C supplementation on oxidative and salivary IgA changes following an ultramarathon (2003) (74)
Characterization of LPS-induced lung inflammation in cftr-/- mice and the effect of docosahexaenoic acid. (2002) (74)
Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimer's disease. (2004) (73)
Zinc deficiency increases plasma lipids and atherosclerotic markers in LDL-receptor-deficient mice. (2005) (73)
Cyclosporine A suppresses keratinocyte cell death through MPTP inhibition in a model for skin cancer in organ transplant recipients. (2010) (71)
Oral quercetin supplementation and blood oxidative capacity in response to ultramarathon competition. (2008) (69)
ISOPROSTANES—RROSTAGLANDIN-LIKE COMPOUNDS FORMED IN VIVO INDEPENDENTLY OF CYCLOOXYGENASE (1996) (67)
COX-2 compensation in the uterus of COX-1 deficient mice during the pre-implantation period (1999) (66)
Intraindividual Variability of Plasma Antioxidants, Markers of Oxidative Stress, C-Reactive Protein, Cotinine, and Other Biomarkers (2006) (64)
Regiochemistry of Neuroprostanes Generated from the Peroxidation of Docosahexaenoic Acid in Vitro and in Vivo* (2005) (64)
Cell proliferation and apoptotic indices predict adenoma regression in a placebo-controlled trial of celecoxib in familial adenomatous polyposis patients. (2004) (63)
Increased levels of F2-isoprostanes following aneurysmal subarachnoid hemorrhage in humans. (2006) (63)
Levels of Prostaglandin E Metabolite, the Major Urinary Metabolite of Prostaglandin E2, Are Increased in Smokers (2005) (62)
Increased dietary NaCl induces renal medullary PGE2 production and natriuresis via the EP2 receptor. (2008) (62)
Formation of isoprostane bicyclic endoperoxides from the autoxidation of cholesteryl arachidonate. (2002) (61)
Effect of resistance exercise and carbohydrate ingestion on oxidative stress (2005) (61)
Cyclopentenone Eicosanoids as Mediators of Neurodegeneration: A Pathogenic Mechanism of Oxidative Stress‐Mediated and Cyclooxygenase‐Mediated Neurotoxicity (2005) (61)
Nitric oxide synthesis and isoprostane production in subjects with type 1 diabetes and normal urinary albumin excretion. (2000) (61)
Consumption of blueberry polyphenols reduces exercise-induced oxidative stress compared to vitamin C (2004) (61)
Induction of apoptosis by chemotherapeutic drugs without generation of reactive oxygen species. (2002) (60)
Lipids versus proteins as major targets of pro-oxidant, direct-acting hemolytic agents. (2005) (60)
Detection of the major urinary metabolite of prostaglandin D2 in the circulation: demonstration of elevated levels in patients with disorders of systemic mast cell activation. (1994) (58)
A novel mechanism for vasoconstrictor action of 8-isoprostaglandin F2 alpha on retinal vessels. (1998) (57)
Liver and kidney necrosis in selenium-deficient rats depleted of glutathione. (1995) (57)
Acute hyperlipidemia increases oxidative stress more in African Americans than in white Americans. (2003) (56)
Identification of a Novel Class of Endoperoxides from Arachidonate Autoxidation* (2004) (56)
Correlation between two markers of inflammation, serum C-reactive protein and interleukin 6, and indices of oxidative stress in patients with high risk of cardiovascular disease (2008) (56)
Dietary supplementation of omega-3 fatty acid-containing fish oil suppresses F2-isoprostanes but enhances inflammatory cytokine response in a mouse model of ovalbumin-induced allergic lung inflammation. (2009) (56)
Identification of Novel Autoxidation Products of the ω-3 Fatty Acid Eicosapentaenoic Acid in Vitro and in Vivo* (2007) (55)
Mechanisms for the Formation of Isoprostane Endoperoxides from Arachidonic Acid (2003) (55)
Ibuprofen use during extreme exercise: effects on oxidative stress and PGE2. (2007) (55)
Plant catechols prevent lipid peroxidation in human plasma and erythrocytes (2001) (54)
F2-Isoprostanes as Biomarkers of Late-onset Alzheimer’s Disease (2007) (54)
Influence of Carbohydrate Ingestion on Oxidative Stress and Plasma Antioxidant Potential Following a 3 h Run (2003) (53)
Neuropeptide Y, a putative cotransmitter in noradrenergic neurons, induces mast cell degranulation but not prostaglandin D2 release. (1991) (53)
Improved diagnosis of mastocytosis by measurement of the major urinary metabolite of prostaglandin D2. (1995) (53)
Supplementation with vitamin E but not with vitamin C lowers lipid peroxidation in vivo in mildly hypercholesterolemic men (2001) (52)
In-vivo effects of Glu298Asp endothelial nitric oxide synthase polymorphism. (2001) (52)
Oxidative stress in fibromyalgia and its relationship to symptoms (2009) (52)
Biomarker responses and disease susceptibility in juvenile rainbow trout Oncorhynchus mykiss fed a high molecular weight PAH mixture (2011) (51)
In Vivo Oxidative Damage in Rats Is Associated with Barbiturate Response but Not Other Cytochrome P450 Inducers (2007) (51)
Separation and identification of F2-isoprostane regioisomers and diastereomers by novel liquid chromatographic/mass spectrometric methods. (2005) (51)
Correlation of F4-neuroprostanes levels in cerebrospinal fluid with outcome of aneurysmal subarachnoid hemorrhage in humans. (2009) (51)
Collision-induced dissociation of F2-isoprostane-containing phospholipids. (1993) (51)
Effects of vitamin E on oxidative stress and atherosclerosis in an obese hyperlipidemic mouse model. (2007) (50)
Cerebrospinal fluid abeta42, tau, and f2-isoprostane concentrations in patients with Alzheimer disease, other dementias, and in age-matched controls. (2001) (50)
Brassica vegetable consumption reduces urinary F2-isoprostane levels independent of micronutrient intake. (2006) (49)
Prolonged α-Tocopherol Deficiency Decreases Oxidative Stress and Unmasks α-Tocopherol-dependent Regulation of Mitochondrial Function in the Brain* (2008) (48)
Improved assay for the quantification of 11-dehydrothromboxane B2 by gas chromatography-mass spectrometry. (1993) (48)
Signaling through the Prostaglandin I2 Receptor IP Protects against Respiratory Syncytial Virus-Induced Illness (2004) (48)
Identification of intact oxidation products of glycerophospholipids in vitro and in vivo using negative ion electrospray iontrap mass spectrometry. (2009) (47)
Urinary F2-isoprostanes are not associated with increased risk of type 2 diabetes. (2005) (46)
Cyclooxygenase Inhibition Augments Allergic Inflammation through CD4-Dependent, STAT6-Independent Mechanisms1 (2005) (46)
Dietary fish oil exerts hypolipidemic effects in lean and insulin sensitizing effects in obese LDLR-/- mice. (2009) (46)
Biphenotypic B / macrophage cells express COX‐1 and up‐regulate COX‐2 expression and prostaglandin E2 production in response to pro‐inflammatory signals (1999) (46)
Isoprostanes and related compounds: update 2006. (2006) (46)
Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury. (2004) (46)
Associations between apolipoprotein E genotype and circulating F2-isoprostane levels in humans (2005) (45)
Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse. (1999) (45)
Hydrogen peroxide induces 21-aminosteroid-inhibitable F2-isoprostane production and cytolysis in renal tubular epithelial cells. (1995) (45)
Quantification of BK1-5, the stable bradykinin plasma metabolite in humans, by a highly accurate liquid-chromatographic tandem mass spectrometric assay. (2001) (45)
Cyclooxygenase-1-dependent Prostaglandin Synthesis Modulates Tumor Necrosis Factor-α Secretion in Lipopolysaccharide-challenged Murine Resident Peritoneal Macrophages* (2004) (45)
2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite. (2001) (44)
No difference in plasma or urinary F2‐isoprostanes among patients with Huntington's disease or Alzheimer's disease and controls (2000) (44)
Improved assay for the quantification of the major urinary metabolite of the isoprostane 15-F(2t)-Isoprostane (8-iso-PGF(2alpha)) by a stable isotope dilution mass spectrometric assay. (2001) (44)
Hypertrophic osteoarthropathy pathogenesis: a case highlighting the potential role for cyclo-oxygenase-2-derived prostaglandin E2 (2006) (43)
Neurotoxic lipid peroxidation species formed by ischemic stroke increase injury. (2009) (43)
In vivo and in vitro lipid peroxidation of arachidonate esters: the effect of fish oil omega-3 lipids on product distribution. (2006) (43)
The cyclopentenone (A2/J2) isoprostanes--unique, highly reactive products of arachidonate peroxidation. (2005) (43)
Simplified assay for the quantification of 2,3-dinor-6-keto-prostaglandin F1 alpha by gas chromatography-mass spectrometry. (1994) (43)
Antioxidant susceptibility of pathogenic pathways in subjects with antiphospholipid antibodies: a pilot study (2000) (43)
The cyclopentenone product of lipid peroxidation, 15-A2t-isoprostane, is efficiently metabolized by HepG2 cells via conjugation with glutathione. (2004) (42)
A series of prostaglandin F 2-like compounds are produced in vivo in humans by a non-cyclooxygenase , free radical-catalyzed mechanism ( eicosanoids / oxidative stress / lipid peroxidation / mass spectrometry ) (42)
Sulindac sulfide, but not sulindac sulfone, inhibits colorectal cancer growth. (1999) (41)
Primaquine-Induced Hemolytic Anemia: Effect of 6-Methoxy-8-hydroxylaminoquinoline on Rat Erythrocyte Sulfhydryl Status, Membrane Lipids, Cytoskeletal Proteins, and Morphology (2002) (40)
Highly Sensitive C-Reactive Protein, Body Mass Index, and Serum Lipids in HIV-Infected Persons Receiving Antiretroviral Therapy: A Longitudinal Study (2009) (39)
Prostaglandin E2 Is a Product of Induced Prostaglandin-endoperoxide Synthase 2 and Microsomal-type Prostaglandin E Synthase at the Implantation Site of the Hamster* (2004) (39)
Increased Cerebral Cortical Lipid Peroxidation and Abnormal Phospholipids in Aged Homozygous apoE-Deficient C57BL/6J Mice (1999) (39)
Primaquine-Induced Hemolytic Anemia: Role of Membrane Lipid Peroxidation and Cytoskeletal Protein Alterations in the Hemotoxicity of 5-Hydroxyprimaquine (2005) (39)
RAW264.7 cells lack prostaglandin-dependent autoregulation of tumor necrosis factor-α secretion Published, JLR Papers in Press, February 1, 2005. DOI 10.1194/jlr.M500006-JLR200 (2005) (39)
Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNγ-dependent iNOS expression in the vasculature of healthy mice (2008) (38)
Oxidant stress but not thromboxane decreases with epoprostenol therapy. (2005) (38)
F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease. (2007) (38)
The cyclopentenone product of lipid peroxidation, 15-A(2t)-isoprostane (8-isoprostaglandin A(2)), is efficiently conjugated with glutathione by human and rat glutathione transferase A4-4. (2002) (38)
Essential Role of the Redox-Sensitive Kinase p66shc in Determining Energetic and Oxidative Status and Cell Fate in Neuronal Preconditioning (2010) (38)
Antioxidants significantly affect the formation of different classes of isoprostanes and neuroprostanes in rat cerebral synaptosomes. (2003) (38)
Centralized Oversight of Physician–Scientist Faculty Development at Vanderbilt: Early Outcomes (2008) (38)
Up-regulation of the enzymes involved in prostacyclin synthesis via Ras induces vascular endothelial growth factor. (2004) (38)
Herpes simplex virus type 1 encephalitis is associated with elevated levels of F2-isoprostanes and F4-neuroprostanes (2002) (37)
Mass spectrometric quantification of F2-isoprostanes as indicators of oxidant stress. (2002) (37)
Cyclooxygenase-2–Dependent Prostacyclin Formation Is Regulated by Low Density Lipoprotein Cholesterol In Vitro (2002) (37)
Prostaglandin F2α Is Required for NMDA Receptor-Mediated Induction of c-fos mRNA in Dentate Gyrus Neurons (1997) (37)
Cyclooxygenase-1 Deficiency in Bone Marrow Cells Increases Early Atherosclerosis in Apolipoprotein E– and Low-Density Lipoprotein Receptor–Null Mice (2005) (37)
Oncogenic Ras and Transforming Growth Factor-β Synergistically Regulate AU-Rich Element–Containing mRNAs during Epithelial to Mesenchymal Transition (2008) (36)
Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay. (1991) (36)
Angiotensin receptor blockade improves arterial distensibility and reduces exercise-induced pressor responses in obese hypertensive patients with the metabolic syndrome. (2004) (36)
Extracellular Signal-Regulated Kinase Is a Target of Cyclooxygenase-1-Peroxisome Proliferator-Activated Receptor-δ Signaling in Epithelial Ovarian Cancer (2007) (36)
American Society for Clinical Pharmacology and Therapeutics Position Statement on Dietary Supplement Safety and Regulation (2005) (34)
Thromboxane and isoprostanes as inflammatory and vasoactive mediators in black walnut heartwood extract induced equine laminitis. (2009) (34)
Interactions between Apolipoprotein E Gene and Dietary α-Tocopherol Influence Cerebral Oxidative Damage in Aged Mice (2001) (34)
Chronic aminoguanidine attenuates renal dysfunction and injury in aging rats. (1999) (34)
Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin. (1996) (34)
The isoprostanes: unique bioactive products of lipid peroxidation. An overview. (1998) (33)
Effect of NSAID on muscle injury and oxidative stress. (2007) (33)
Ozone causes lipid peroxidation but little antioxidant depletion in exercising and nonexercising hamsters. (2001) (33)
Cisplatin induces N-acetyl cysteine suppressible F2-isoprostane production and injury in renal tubular epithelial cells. (1998) (33)
Quantification of F2-Isoprostanes as a Reliable Index of Oxidative Stress in vivo Using Gas Chromatography—Mass Spectrometry (GC-MS) Method (2010) (33)
Isoprostanes--prostaglandin-like compounds formed in vivo independently of cyclooxygenase: use as clinical indicators of oxidant damage. (1996) (32)
Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans following the application of sorbic acid. (1994) (32)
The isoprostanes: novel markers of lipid peroxidation and potential mediators of oxidant injury. (1995) (32)
Ligand-dependent activation of the epidermal growth factor receptor by secondary bile acids in polarizing colon cancer cells. (2005) (32)
Evidence for the formation of a novel cyclopentenone isoprostane, 15-A2t-isoprostane (8-iso-prostaglandin A2) in vivo. (1999) (32)
Cold storage induces time-dependent F2-isoprostane formation in renal tubular cells and rat kidneys. (1999) (32)
Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver. (2001) (31)
Isoprostanes (1994) (31)
Structural determinants of substrates for the prostaglandin transporter PGT. (1996) (31)
Cyclopentenone prostaglandin, 15-deoxy-Delta12,14-PGJ2, is metabolized by HepG2 cells via conjugation with glutathione. (2007) (31)
Excretion of F2‐isoprostanes in bile: A novel index of hepatic lipid peroxidation (1995) (31)
Effect of 6 weeks of vitamin E administration on renal haemodynamic alterations following a single dose of neoral in healthy volunteers. (2001) (31)
Identification of free radical formation and F2-isoprostanes in vivo by acute Cr(VI) poisoning. (1998) (30)
New developments in the isoprostane pathway: identification of novel highly reactive γ‐ketoaldehydes (isolevuglandins) and characterization of their protein adducts (1999) (30)
Evidence that the E2-isoprostane, 15-E2t-isoprostane (8-iso-prostaglandin E2) is formed in vivo. (1998) (30)
Oncogenic potential of MEK1 in rat intestinal epithelial cells is mediated via cyclooxygenase-2. (2005) (30)
Impairment of the Transcriptional Responses to Oxidative Stress in the Heart of Aged C57BL/6 Mice (2004) (30)
Evidence against peroxisome proliferation-induced hepatic oxidative damage. (1997) (29)
Topical benzoic acid induces the increased biosynthesis of prostaglandin D2 in human skin in vivo (1995) (29)
Isoprostanes as Markers of Lipid Peroxidation in Atherosclerosis (1999) (29)
Lipid Oxidative Markers Are Significantly Increased in Lipoatrophy But Not in Sustained Asymptomatic Hyperlactatemia (2003) (29)
S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor. (2009) (29)
Correction: A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice (2008) (29)
Aspirin therapy and thromboxane biosynthesis in systemic lupus erythematosus (2007) (28)
Formation of F2-isoprostanes during the oxidation of human low density lipoprotein by peroxynitrite. (1995) (28)
Inhaled Nitric Oxide Attenuates Hyperoxic Lung Injury in Lambs (2006) (28)
Nitric oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors. (2006) (27)
The fatty acid oxidation product 15‐A3t‐Isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation (2011) (27)
Case report: dapsone hypersensitivity syndrome associated with treatment of the bite of a brown recluse spider. (1988) (27)
Induction of prostaglandin endoperoxide synthase-1 (COX-1) in a human promonocytic cell line by treatment with the differentiating agent TPA. (1997) (27)
Increased levels of prostaglandin D(2) suggest macrophage activation in patients with primary pulmonary hypertension. (2001) (27)
Non-cyclooxygenase-derived prostanoids ( F 2-isoprostanes ) are formed in situ on phospholipids ( eicosanoids / lipids / oxidative stress / peroxidation / free radicals ) (26)
Evidence that the F2-isoprostane, 8-epi-prostaglandin F2 alpha, is formed in vivo. (1994) (26)
Elevated Levels of Urinary Prostaglandin E Metabolite Indicate a Poor Prognosis in Ever Smoker Head and Neck Squamous Cell Carcinoma Patients (2009) (26)
Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J(2), to glutathione. (2002) (25)
Two Pathways for Cyclooxygenase-2 Protein Degradation in Vivo* (2009) (25)
Extracellular signal-regulated kinase is a target of cyclooxygenase-1-peroxisome proliferator-activated receptor-delta signaling in epithelial ovarian cancer. (2007) (24)
Cimetidine Does Not Prevent Lung Injury in Newborn Premature Infants (2006) (24)
Infections due to non-neoformans cryptococcal species (2003) (24)
Comparison of three oxidative stress biomarkers in a sample of healthy adults (2009) (24)
Original Contribution Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl 4 poisoning (2005) (24)
In vivo aspirin supplementation inhibits nitric oxide consumption by human platelets. (2005) (23)
Quantification of 9 alpha, 11 beta-prostaglandin F2 by stable isotope dilution mass spectrometric assay. (1990) (22)
Clinical Factors Associated with Plasma F2-Isoprostane Levels in HIV-Infected Adults (2009) (22)
Thioredoxin Reductase Reduces Lipid Hydroperoxides and Spares α-Tocopherol (2002) (22)
Allergen-Induced Airway Hyperresponsiveness Mediated by Cyclooxygenase Inhibition Is Not Dependent on 5-Lipoxygenase or IL-5, but Is IL-13 Dependent1 (2005) (21)
Enzyme immunoassays for 15-F2T isoprostane-M, an urinary biomarker for oxidant stress. (2002) (21)
Acute angiotensin II increases plasma F2-isoprostanes in salt-replete human hypertensives. (2003) (21)
Ascorbate-dependent protection of human erythrocytes against oxidant stress generated by extracellular diazobenzene sulfonate. (2000) (21)
Elevated oxidation of docosahexaenoic acid, 22:6 (n −3), in brain regions of rats undergoing ethanol withdrawal (2006) (20)
Identification of the Major Urinary Metabolite of the Highly Reactive Cyclopentenone Isoprostane 15-A2t-Isoprostane in Vivo* (2005) (20)
Ventriculitis due to Cryptococcus uniguttulatus. (2001) (20)
Allergen-induced airway hyperresponsiveness mediated by cyclooxygenase inhibition is not dependent on 5-lipoxygenase or IL-5, but is IL-13 dependent. (2006) (20)
RAW264.7 cells lack prostaglandin-dependent autoregulation of tumor necrosis factor-alpha secretion. (2005) (20)
Degree of heteroplasmy reflects oxidant damage in a large family with the mitochondrial DNA A8344G mutation. (2005) (20)
Carbohydrate effect: hormone and oxidative changes. (2007) (19)
Oxidant Stress and Peripheral Neuropathy During Antiretroviral Therapy: An AIDS Clinical Trials Group Study (2006) (19)
Effect of pharmacological lowering of plasma urate on exercise-induced oxidative stress. (2007) (19)
The Isoprostanes: Novel Prostaglandin-Like Products of the Free Radical-Catalyzed Peroxidation of Arachidonic Acid (1999) (19)
The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells Published, JLR Papers in Press, February 16, 2005. DOI 10.1194/jlr.M500021-JLR200 (2005) (19)
Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans after the application of cinnamic aldehyde. (2001) (19)
INFLUENCE OF VITAMIN C SUPPLEMENTATION ON OXIDATIVE AND IMMUNE CHANGES FOLLOWING AN ULTRAMARATHON (2002) (18)
C18 hydroxy fatty acids as markers of lipid peroxidation ex vivo and in vivo (2004) (18)
Formation of novel isoprostane-like compounds from docosahexaenoic acid. (1999) (17)
Electrophilic Cyclopentenone Isoprostanes in Neurodegeneration (2007) (17)
Influence of carbohydrate, intense exercise, and rest intervals on hormonal and oxidative changes. (2007) (16)
Fluconazole: a new triazole antifungal agent. (1991) (16)
Induction of cyclooxygenase-2 and invasiveness by transforming growth factor-β1 in immortalized mouse colonocytes expressing oncogenic ras (2002) (16)
Increased formation of thromboxane in vivo in humans with mastocytosis. (1999) (16)
Age-independent, gray matter-localized, brain-enhanced oxidative stress in male fischer 344 rats: brain levels of F(2)-isoprostanes and F(4)-neuroprostanes. (2003) (16)
Quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. (2001) (16)
Formation of PGD2 after allergen inhalation in atopic asthmatics. (1991) (15)
F2‐Isoprostanes as Markers of Oxidant Stress: An Overview (2005) (15)
Novel eicosanoids. Isoprostanes and related compounds. (1999) (14)
Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice. (2005) (14)
PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression. (2011) (14)
Oxidant stress in HIV-infected women from the Women's Interagency HIV Study (2009) (14)
Cryofiltration apheresis and plasma fractionation causing anaphylactoid reactions in patients receiving angiotensin converting enzyme inhibitors. (1997) (13)
The enteropathy of prostaglandin deficiency (2008) (13)
Vertebral osteomyelitis due to Candida glabrata. A case report. (1986) (13)
Mouse cerebral prostaglandins, but not oxidative damage, change with age and are responsive to indomethacin treatment (2002) (12)
The antiangiogenic agent SU5416 down-regulates phorbol ester-mediated induction of cyclooxygenase 2 expression by inhibiting nicotinamide adenine dinucleotide phosphate oxidase activity. (2003) (12)
Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. (2008) (12)
Airway function after cyclooxygenase inhibition during hyperpnea-induced bronchoconstriction in guinea pigs. (2000) (12)
Effect of endotoxin on oleic acid lung injury does not depend on priming. (2001) (12)
A Phase I Study of Vitamin E, 5-Fluorouracil and Leucovorin for Advanced Malignancies (2001) (12)
Quantification of Isoprostanes as Indicators of Oxidant Stress in Vivo (2001) (11)
Cyclosporine-induced alterations in renal function are not associated with lipid peroxidation. (1994) (11)
Restoration of On-Time Embryo Implantation Corrects the Timing of Parturition in Cytosolic Phospholipase A2 Group IVA Deficient Mice1 (2009) (11)
Formation of unique biologically active prostaglandins in vivo by a non-cyclooxygenase free radical catalyzed mechanism. (1991) (11)
20-Hydroxylation is the CYP-dependent and retinoid-inducible leukotriene B4 inactivation pathway in human and mouse skin cells. (2009) (11)
Sex Differences in Urinary Biomarkers of Vascular and Endothelial Function in HIV-Infected Persons Receiving Antiretroviral Therapy (2011) (10)
Use of a database computer program to identify trends in reporting of adverse drug reactions. (1990) (10)
Evidence that the E 2 -isoprostane, 15-E 2t -isoprostane (8-iso-prostaglandin E 2 ) is formed in vivo (1998) (10)
Diet as a Modifier of Benzo(a)pyrene Metabolism and Benzo(a)pyrene—Induced Colon Tumors in Apc Min mice (2009) (10)
Divergence of brain prostaglandin H synthase activity and oxidative damage in mice with encephalitis. (1999) (9)
Drugs to Treat Systemic Lupus Erythematosus: Relationship between Current Use and Cardiovascular Risk Factors (2008) (9)
F2-isoprostanes and the kidney. (1998) (8)
Cell proliferation and apoptotic indices predict adenoma regression in a placebo-controlled trial of celecoxib in familial adenomatous polyposis (FAP) patients (2003) (8)
Thioredoxin reductase reduces lipid hydroperoxides and spares alpha-tocopherol. (2002) (8)
p66shc's role as an essential mitophaghic molecule in controlling neuronal redox and energetic tone (2010) (8)
F2-ISOPROSTANES (F2I) IN TRACHEOBRONCHIAL ASPIRATE FLUID (TBAF) INDICATE ASSOCIATION BETWEEN INCREASED FIO2 AND LIPID PEROXIDATION IN THE LUNGS OF PREMATURE INFANTS. ▴ 1957 (1996) (7)
Simplification of the mass spectrometric assay for the major urinary metabolite of prostaglandin D2. (1993) (7)
Proinflammatory Signals Upregulate COX‐2 and Increase PGE2 Production in Biphenotypic B/Macrophage Cells (2000) (7)
Formation of novel D-ring and E-ring isoprostane-like compounds (D4/E4-neuroprostanes) in vivo from docosahexaenoic acid. (1999) (7)
The oral cephalosporins--a review. (1992) (7)
Inducible Nitric Oxide Synthase Regulates Production of Isoprostanes In Vivo during Chlamydial Genital Infection in Mice (2003) (7)
Introduction for special forum issue on isoprostanes and related compounds. (2005) (6)
Survival after intrahepatic cholestasis associated with sickle cell disease. (1986) (5)
Relation of preservation of nitric oxide-dependent coronary vasomotor function to plasma vitamin C concentrations in cardiac transplant recipients. (2000) (5)
Eicosanoid production and growth regulation in rat intestinal epithelial cells. (1997) (5)
A stable isotope dilution mass spectrometric assay for the major urinary metabolite of PGD2. (1991) (5)
Thromboxane A2 is a mediator of COX-2 dependent endothelial migration & angiogenesis (1999) (4)
Analysis of F 2 -Isoprostanes by Gas Chromatography-Mass Spectrometry/Negative Ion Chemical Ionization (2003) (4)
Quantification of F2‐Isoprostanes by Gas Chromatography/Mass Spectrometry as a Measure of Oxidant Stress (2005) (4)
Topics in Clinical Pharmacology: Pancreatic Enzyme Replacement Therapy (1989) (4)
Formation of Prostaglandin E 2 and Prostaglandin D 2 Via the Isoprostane Pathway: A Mechanism for the Generation of Bioactive Prostaglandins Independent of the Cyclooxygenase (2003) (3)
FROM COAL STACKS TO COLON CANCER—ARE POLYCYCLIC AROMATIC HYDROCARBONS THE CULPRITS? (2008) (3)
Expression of cyclooxygenase-2 and prostaglandins by B-1 cells and B-CLL cells. (2000) (3)
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Secondary bile acids activate the epidermal growth factor receptor (EGFR) through a SRC kinase-mediated release of EGFR ligands in polarizing colon cancer cells (2006) (3)
Interaction of Ascorbate and -Tocopherol in Resealed Human Erythrocyte Ghosts (1996) (3)
Levels of Prostaglandin EMetabolite , theMajor UrinaryMetabolite of Prostaglandin E 2 , Are Increased in Smokers (2005) (3)
Primary hepatic actinomycosis--diagnosis by percutaneous transhepatic needle aspiration. (1993) (3)
Measurement of Biological Materials (2009) (3)
Long‐Term Vitamin E Deficiency in Mice Decreases Superoxide Radical Production in Brain (2004) (3)
Effect of vitamins C and E on biomarkers of oxidative stress in nonsmokers (2009) (3)
Eaton-Lambert syndrome in a patient with acute T cell lymphocytic leukemia. (1988) (3)
Prosthetic cranioplasty infection due to Sporobolomyces. (1994) (2)
Correction: A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice (2008) (2)
Pharmacologic Strategies for Suppression of Lipid Peroxidation in Neurodegeneration (2003) (2)
P-357 Cyclooxygenase-2 (COX-2) inhibition in advanced non-small cell lung cancer (NSCLC): preliminary results of a phase II trial (THO-0054) (2003) (2)
Dietary Fish Oil Exerts Hypolipidemic Effects in Lean and Insulin Sensitizing Effects in Obese LDLR 2 / 2 Mice 1–3 (2009) (2)
The Role of Oxidative Stress in Diseases Associated with Overweight and Obesity (2007) (2)
F2Isoprostanes (F2I) in Tracheobronchial Aspirate (TBA) Within 24 Hours After Birth Predict Bronchopulmonary Dysplasia (BPD) ♦ 1631 (1998) (2)
Formation of reactive products of the isoprostane pathway: isolevuglandins and cyclopentenone isoprostanes. (1999) (2)
Identification of Novel Prostaglandin-Containing Glycerophospholipids in vivo (1993) (2)
Prostacyclin and Thromboxane and the Development of Preeclampsia—Reply (2000) (1)
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Agonists γ Proliferator Activation Receptor-and 2 Mice by Prostaglandin J lpr MRL / Inhibition of Mesangial Cell Nitric Oxide in (2000) (1)
Prostaglandin (PG) E2 and PGD2 are formed in significant quantities via the isoprostane pathway in vivo (1999) (1)
Pantothenic acid: an organ-specific pro-oxidant vitamin. Brain and liver neuroprostane levels in rats fed a pantothenic acid-deficient diet. (2002) (1)
P-351 The antiangiogenic agent SU5416 downregulates phorbol ester-mediated induction of cyclooxygenase-2 expression by inhibiting NADPH oxidase (2003) (1)
Urine PGE-M as a marker of intratumoral cyclooxygenase-2 activity in non-small cell lung cancer (NSCLC) (2004) (1)
Aminoguanidine improves renal function and attenuates glomerular injury in aging rats (1997) (1)
Quantification of Isoprostanes as an Index of Oxidant Stress Status In Vivo (2002) (1)
Urine PGE-M to assess prostaglandin E2 (PGE2) levels in non-small cell lung cancer (NSCLC). (2009) (1)
A Phase II Study of Celecoxib in Combination With Paclitaxel, Carboplatin, and Radiation Therapy for Patients With Inoperable Stage IIIA/B Non-Small Cell Lung Cancer (2007) (1)
Fulminant Kaposi's sarcoma without mucocutaneous disease. (2003) (1)
Development of immunoassays for 5,6-, 8,9- 11,12-, and 14-15 epoxyeicosatrienoic acids (EETs) and corresponding dihydroxyeicosatrienoic acids (DHETs) (1999) (1)
Correction: A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice (2008) (1)
Biology and Chemistry of Products of the Isoprostane Pathway (2004) (0)
Cerebrospinal fluid levels of F2‐isoprostanes in patients with neurodegenerative diseases (1999) (0)
COMMENTS ON PROSTAGLANDIN F2ALPHA RISES IN RESPONSE TO HYDROXYL RADICAL GENERATED IN VIVO. AUTHOR'S REPLY (1995) (0)
Vanderbilt morning report. A case of syncope. (1998) (0)
EFFECT OF EXERCISE AND HYPERTHERMIA ON INDICES OF OXIDATIVE STRESS (2001) (0)
NON-ENZYMATIC OMEGA-3-FATTY ACID BREAK-DOWN PRODUCTS ARE DIFFERENTIALLY EXPRESSED IN RHEUMATOID ARTHRITIS AND SUPPRESS NFKB ACTIVITY TO INHIBIT OSTEOCLAST FORMATION (2012) (0)
Abstract 10544: Cocoa Increases Plasma Epicatechin Concentrations in Hyperlipidemic Children Without Adverse Effects on the Lipid Profile or Markers of Oxidative Stress (2011) (0)
Formation and Metabolism of 15-Deoxy-Δ12,14Prostaglandin J2 (2010) (0)
Detection of lipid peroxidation in vivo in selenium and vitamin E deficiency (1993) (0)
Comments on prostaglandin F2 alpha rises in response to hydroxyl radical generated in vivo. (1995) (0)
A case of pneumococcal meningitis. (2000) (0)
APhase II Study of Celecoxib in Combinationwith Paclitaxel, Carboplatin, and Radiotherapy for Patients with Inoperable Stage IIIA/BNon^Small Cell Lung Cancer (2009) (0)
Inhibition of F2-isoprostane synthesis reduces proteinuria and improves renal function in streptozotocin (STZ)-induced diabetic rats (1999) (0)
DOES ASCORBIC ACID AND FREE IRON IN PLASMA OF PRETERM INFANTS CAUSE OXIDATIVE DAMAGE? † 1156 (1996) (0)
Development of a competititve immunometric enzyme-linked immunosorbent assay (ELISA) for the major human urinary metabolite of 15-F2T-isoprostane, a noninvasive biomarker for oxidant stress (1999) (0)
PII‐5 (2006) (0)
Reply (2003) (0)
Constitutively activated MEK1 represses sodium butyrate induced cell differentiation and apoptosis in rat intestinal epithelial cells (2003) (0)
vasculature of healthy mice -dependent iNOS expression in the γ suppressing bacteria and IFN Circulating neutrophils maintain physiological blood pressure by (2013) (0)
Assessment of oxidative stress in the rat model of chronic dietary iron overload (IO) (1993) (0)
Augmentation of allergic inflammation by cyclooxygenase inhibition is not dependent on IL-4 (2002) (0)
PPARγ and β-catenin interact to regulate COX-2 expression induced by insulin in HT-29 colon cancer cells (2001) (0)
A case of alcoholic ketoacidosis. (1987) (0)
Phase II study of the clinical and biological activity of cetuximab and celecoxib in patients (pts) with refractory colorectal cancer (CRC) (2007) (0)
Role of short-term α-lipoic acid therapy in patients with hypercholesterolemia to reverse oxidative stress and endothelial dysfunction (2015) (0)
O'Neill, Onora. Autonomy and Trust in Bioethics (2003) (0)
Correction: Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the ω -3 polyunsaturated fatty acid docosahexaenoic acid. (2019) (0)
Why Markets in Human Organs Should be Legalized (2013) (0)
A man with a large abdominal mass. (1988) (0)
PII‐14 (2006) (0)
A case of typhoid fever. (1988) (0)
Oral ulcerations in a patient with sarcoidosis. (1999) (0)
Smad4 independent induction of COX-2 by transforming growth factor-B1 (TGF-B1) in human pancreatic carcinoma (BXPC-3) cells (2000) (0)
Lipid peroxidation: from basic mechanisms to clinical relevance (2007) (0)
depletion in exercising and nonexercising hamsters Ozone causes lipid peroxidation but little antioxidant (2015) (0)
A young man with meningitis and purpura. (1988) (0)
Pancytopenia in an elderly woman. (1988) (0)
A Phase I Study of Neoadjuvant Cyclooxygenase-2 Inhibition and Chemoradiation for Stage II/III Rectal Cancer (2007) (0)
Comparative evaluation of measuring Tbars and F2-isoprostanes in the assessment of lipid peroxidation in vitro and in vivo (1993) (0)
Comments on prostaglandin F2α rises in response to hydroxyl radical generated in vivo (1995) (0)
Non-Cyclooxygenase Oxidative Formation of a Series of Novel Prostaglandins: Ramifications for the Measurement of Eicosanoids in Biological Fluids (1990) (0)
EFFECT OF CIMETIDINE ON LIPID PEROXIDATION IN THE LUNGS OF PREMATURE NEWBORN INFANTS. † 1956 (1996) (0)
receptor 2 signaling induces COX-2 expression in Wilms tumor (2014) (0)
Reactive Products of the Isoprostane Pathway: Isoketals and Cyclopentenone A2/J2-Isoprostanes (2001) (0)
STAT6-Independent Mechanisms Inflammation through CD4-Dependent, Cyclooxygenase Inhibition Augments Allergic (2013) (0)
O.19 Pro- or antioxidant activity of ascorbic acid in thepresence of ‘free’ iron in plasma of preterm infants? (1996) (0)
Development of an accurate method to quantify F4-neuroprostanes in vivo in humans (2002) (0)
Comparison of Enzyme Immunoassays with Gas Chromatography -Isoprostanes as Markers of in Vivo Lipid Peroxidation: A 2 Measurement of Urinary F (2015) (0)
Eicosanoids in non-small cell lung cancer (NSCLC). (2010) (0)
Abstract B85: Comparison of three oxidative stress biomarkers in a sample of healthy adults (2008) (0)
Formation of free radical-derived F2-isoprostanes in human plasma and LDL (1993) (0)
7The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells (2005) (0)
Herpes simplex virus type 1 ( HSV-1 ) is an important pathogen infecting the vast majority of humans (2005) (0)
Augmentation of allergic inflammation by cyclooxygenase (COX) inhibition does not depend on STAT6 signaling (2003) (0)
Cancer Small Cell Lung − in Non α via Hypoxia-Inducible Factor-1 Thioredoxin-1 Modulates Transcription of Cyclooxygenase-2 Updated (2005) (0)
Preliminary results of a phase II study of cyclooxygenase-2 (COX-2) inhibition in rectal cancer (2004) (0)
Vanderbilt morning report. A case of alcoholic ketoacidosis. (1998) (0)
Biliary obstruction induces an oxidant injury in the rat small intestine (2001) (0)
Cyclooxygenase (COX) inhibition at the time of initial antigen presentation results in enhanced IL-13 and IgE (2003) (0)
Splicing mutation of the prostacyclin synthase gene in a family associated with hypertension. (2004) (0)
2045 THE ASSOCIATION BETWEEN OXIDATIVE STRESS AND PROSTATE CANCER RISK IN MEN UNDERGOING PROSTATE BIOPSY (2010) (0)
-prostaglandin J2 Induce Proliferation of Cyclooxygenase-depleted Colorectal Cancer Cells (2000) (0)
PII‐10 (2006) (0)
Transforming growth factor-β1 (TGF-β1) induces cyclooxygenase-2 and prostaglandin E2 synthesis in human colon adenoma cells (1998) (0)
Oxidant stress in the pathogenesis of the hepatorenal syndrome (1993) (0)
W1146 Novel Biomarkers of Ulcerative Colitis Activity: A Comparison of Urinary PGE-M, Fecal Calprotectin and C- Reactive Protein (CRP) Levels (2008) (0)
Isoprostane levels are altered in rheumatoid arthritis and suppress NFκB activity to inhibit osteoclast formation (2011) (0)
The Antiangiogenic Agent SU 5416 Down-Regulates Phorbol Ester-Mediated Induction of Cyclooxygenase 2 Expression by Inhibiting Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activity 1 (2003) (0)
A CASE OF SYNCOPE (1998) (0)
INFLUENCE OF VITAMIN C SUPPLEMENTATION ON SALIVARY IGA CHANGES FOLLOWING AN ULTRAMARATHON (2002) (0)
Pancreatic enzyme replacement therapy. (1989) (0)
7 FIRST DESCRIPTION: CYTOSOLIC PHOSPHOLIPASE A2-a DEFICIENCY. (2006) (0)
Dependent on 5-Lipoxygenase or IL-5 , but Is IL-13 Cyclooxygenase Inhibition Is Not Dependent Hyperresponsiveness Mediated by Allergen-Induced Airway (2005) (0)
Carbohydrate Ingestion, Oxidative Stress, and Plasma Antioxidant Potential Following Intensive Resistance Training (2004) (0)
Urine PGE-M as a marker of intratumoral cyclooxygenase-2 activity in non-small cell lung cancer (NSCLC). (2004) (0)
Effect of Blueberry Ingestion on Oxidative Stress and Plasma Antioxidant Potential Following a 2.5 Hour Run (2004) (0)
Influence Of Carbohydrate/placebo On Oxidative Changes And Plasma Antioxidant Capacity Following 2.5-hours Of Intensive Cycling: 2301 Board #90 10:30AM ??? 12:00PM (2005) (0)
Induction of COX-2 and invasiveness by transforming growth factor-β1 in immortalized mouse colonocytes expressing oncogenic ras (2001) (0)
Prostaglandin production is significantly decreased in mice deficient in inducible nitric oxide synthase (1999) (0)
PII‐11 (2006) (0)

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