Jasti S. Rao
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Jasti S. Raobiology Degrees
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Molecular Biology
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Biochemistry
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Biology
Jasti S. Rao's Degrees
- PhD Biochemistry University of California, San Francisco
- Masters Molecular Biology Stanford University
- Bachelors Biology Stanford University
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(Suggest an Edit or Addition)Jasti S. Rao's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Molecular mechanisms of glioma invasiveness: the role of proteases (2003) (846)
- A chronic inflammatory response dominates the skeletal muscle molecular signature in dystrophin-deficient mdx mice. (2002) (416)
- Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. (1996) (299)
- Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis (2004) (296)
- Elevated Levels of Mr 92,000 Type IV Collagenase in Human Brain Tumors (1993) (248)
- Cathepsin B as a cancer target (2013) (242)
- Extraocular muscle is defined by a fundamentally distinct gene expression profile (2001) (216)
- Overexpression of E2F‐1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo (1998) (179)
- YKL-40 and Matrix Metalloproteinase-9 as Potential Serum Biomarkers for Patients with High-Grade Gliomas (2006) (178)
- MMP‐2 alters VEGF expression via αVβ3 integrin‐mediated PI3K/AKT signaling in A549 lung cancer cells (2009) (175)
- Vitronectin, a glioma-derived extracellular matrix protein, protects tumor cells from apoptotic death. (1999) (174)
- Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion. (2000) (173)
- Expression and localization of urokinase-type plasminogen activator receptor in human gliomas. (1994) (168)
- Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo. (1994) (165)
- Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo (2004) (164)
- Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody. (1993) (162)
- Beta-catenin expression is altered in human colonic aberrant crypt foci. (2001) (160)
- RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo. (2006) (160)
- RNA Interference-directed Knockdown of Urokinase Plasminogen Activator and Urokinase Plasminogen Activator Receptor Inhibits Prostate Cancer Cell Invasion, Survival, and Tumorigenicity in Vivo* (2005) (158)
- Matrix metalloproteinases and their biological function in human gliomas (1999) (150)
- Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus-mediated transfer of antisense uPAR and MMP-9 in non–small cell lung cancer cells (2005) (149)
- RNAi-mediated inhibition of cathepsin B and uPAR leads to decreased cell invasion, angiogenesis and tumor growth in gliomas (2004) (148)
- Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway (2010) (145)
- Mechanisms of angiogenesis in gliomas (2006) (145)
- Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity (2012) (136)
- The role of integrins in the malignant phenotype of gliomas. (1999) (135)
- Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo. (1997) (134)
- Specific Interference of Urokinase-type Plasminogen Activator Receptor and Matrix Metalloproteinase-9 Gene Expression Induced by Double-stranded RNA Results in Decreased Invasion, Tumor Growth, and Angiogenesis in Gliomas* (2005) (128)
- MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells. (2012) (123)
- Axonal remyelination by cord blood stem cells after spinal cord injury. (2007) (122)
- Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma (2008) (122)
- Essential role of cooperative NF-κB and Stat3 recruitment to ICAM-1 intronic consensus elements in the regulation of radiation-induced invasion and migration in glioma (2013) (120)
- Proteases and Glioma Angiogenesis (2005) (120)
- Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas (2004) (117)
- Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN (2001) (115)
- Role of MMP-2 in the Regulation of IL-6/Stat3 Survival Signaling via Interaction With α5β1 Integrin in glioma (2012) (111)
- In vitro inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor (1997) (111)
- Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells (2003) (110)
- MMP-2 siRNA Inhibits Radiation-Enhanced Invasiveness in Glioma Cells (2011) (110)
- Downregulation of uPA, uPAR and MMP-9 using small, interfering, hairpin RNA (siRNA) inhibits glioma cell invasion, angiogenesis and tumor growth. (2004) (110)
- Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro (1997) (107)
- Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors. (1993) (107)
- Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells (2010) (107)
- Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells (2010) (103)
- Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth. (1999) (103)
- Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors (2007) (102)
- Loss of fragile histidine triad expression in colorectal carcinomas and premalignant lesions. (2000) (99)
- Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro (2002) (97)
- RNAi‐mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease‐9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth (2007) (96)
- Adenovirus-mediated expression of antisense MMP-9 in glioma cells inhibits tumor growth and invasion (2002) (93)
- Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis (2003) (92)
- Regulation of ProMMP-1 and ProMMP-3 activation by tissue factor pathway inhibitor-2/matrix-associated serine protease inhibitor. (1999) (90)
- Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas (2010) (89)
- Down-regulation of uPAR and uPA activates caspase-mediated apoptosis and inhibits the PI3K/AKT pathway. (2007) (89)
- Matrix metalloproteinase-1 promotes prostate tumor growth and metastasis. (2008) (89)
- Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents. (2001) (89)
- Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells (2001) (89)
- Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth. (2003) (88)
- Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis (2004) (88)
- Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer. (2007) (87)
- Intraperitoneal Injection of a Hairpin RNA–Expressing Plasmid Targeting Urokinase-Type Plasminogen Activator (uPA) Receptor and uPA Retards Angiogenesis and Inhibits Intracranial Tumor Growth in Nude Mice (2007) (84)
- Overexpression and localization of cathepsin B during the progression of human gliomas (2004) (84)
- Inherited predisposition to glioma. (2010) (82)
- Umbilical Cord Blood Stem Cell Mediated Downregulation of Fas Improves Functional Recovery of Rats after Spinal Cord Injury (2007) (81)
- Cord Blood Stem Cell-Mediated Induction of Apoptosis in Glioma Downregulates X-Linked Inhibitor of Apoptosis Protein (XIAP) (2010) (76)
- Adenovirus-Mediated Expression of Antisense Urokinase Plasminogen Activator Receptor and Antisense Cathepsin B Inhibits Tumor Growth, Invasion, and Angiogenesis in Gliomas (2004) (76)
- Induction of Matrix Metalloproteinase-9 Requires a Polymerized Actin Cytoskeleton in Human Malignant Glioma Cells* (1998) (76)
- Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma (2012) (76)
- Modulation of matrix metalloprotease-2 and invasion in human glioma cells by α3β1 integrin (1996) (76)
- Mesenchymal Stem Cells from Rat Bone Marrow Downregulate Caspase-3-mediated Apoptotic Pathway After Spinal Cord Injury in Rats (2007) (75)
- Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer. (2009) (74)
- Concepts in in vivo siRNA delivery for cancer therapy (2009) (74)
- Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice (2006) (74)
- Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells (2010) (74)
- Modulation of cystatin C expression impairs the invasive and tumorigenic potential of human glioblastoma cells (2002) (73)
- Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis. (2007) (73)
- A novel function of tissue factor pathway inhibitor-2 (TFPI-2) in human glioma invasion (2001) (72)
- Overexpression of tissue factor pathway inhibitor-2 (TFPI-2), decreases the invasiveness of prostate cancer cells in vitro. (2001) (69)
- Chk2-mediated G2/M cell cycle arrest maintains radiation resistance in malignant meningioma cells. (2011) (68)
- Irradiation-induced angiogenesis is associated with an MMP-9-miR-494-syndecan-1 regulatory loop in medulloblastoma cells (2014) (68)
- Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1 (2011) (68)
- Intermittent Hypoxia Regulates Stem-like Characteristics and Differentiation of Neuroblastoma Cells (2012) (67)
- Immunohistochemical localization of extracellular matrix proteins in human glioma, both in vivo and in vitro. (1996) (67)
- Antiangiogenic therapy in brain tumors (2008) (67)
- Inhibition of in vivo tumorigenicity and invasiveness of a human glioblastoma cell line transfected with antisense uPAR vectors (1997) (67)
- Effects of irradiation on tumor cell survival, invasion and angiogenesis (2010) (66)
- Temporal Regulation of Apoptotic and Anti-apoptotic Molecules After Middle Cerebral Artery Occlusion Followed by Reperfusion (2013) (66)
- Suppression of the uPAR–uPA System Retards Angiogenesis, Invasion, and In Vivo Tumor Development in Pancreatic Cancer Cells (2011) (66)
- siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells. (2006) (66)
- Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), in human glioma cells (2003) (66)
- Human umbilical cord blood stem cells upregulate matrix metalloproteinase-2 in rats after spinal cord injury (2009) (65)
- p53- and Bax-Mediated Apoptosis in Injured Rat Spinal Cord (2011) (64)
- Expression and immunohistochemical localization of cathepsin L during the progression of human gliomas (2004) (63)
- Expression of tissue factor pathway inhibitor 2 inversely correlates during the progression of human gliomas. (2001) (63)
- SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA. (2006) (61)
- Suppression of human glioma growth by adenovirus-mediated Rb gene transfer (1998) (61)
- Expression of tissue inhibitors of metalloproteinases: negative regulators of human glioblastoma invasion in vivo (2004) (59)
- Inhibition of matrix metalloproteinase‐2 enhances radiosensitivity by abrogating radiation‐induced FoxM1‐mediated G2/M arrest in A549 lung cancer cells (2009) (59)
- Neuroprotection by cord blood stem cells against glutamate-induced apoptosis is mediated by Akt pathway (2008) (58)
- Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor (2011) (58)
- RNAi-mediated abrogation of cathepsin B and MMP-9 gene expression in a malignant meningioma cell line leads to decreased tumor growth, invasion and angiogenesis. (2007) (58)
- Glioma stem cell invasion through regulation of the interconnected ERK, integrin α6 and N-cadherin signaling pathway. (2012) (57)
- Recombinant adeno‐associated virus (rAAV) expressing TFPI‐2 inhibits invasion, angiogenesis and tumor growth in a human glioblastoma cell line (2005) (57)
- Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells. (2003) (56)
- Expression and the role of cathepsin H in human glioma progression and invasion. (1996) (56)
- Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer. (2008) (56)
- Blockade of Tumor Growth Due to Matrix Metalloproteinase-9 Inhibition Is Mediated by Sequential Activation of β1-Integrin, ERK, and NF-κB* (2008) (55)
- Inhibition of Histone Deacetylase Activity Promotes Invasion of Human Cancer Cells through Activation of Urokinase Plasminogen Activator* (2007) (55)
- Suppression of uPAR Retards Radiation-Induced Invasion and Migration Mediated by Integrin β1/FAK Signaling in Medulloblastoma (2010) (54)
- Decrease in plasminogen activator correlates with synapse elimination during neonatal development of mouse skeletal muscle. (1989) (54)
- Inducible nitric oxide synthase (iNOS) is expressed similarly in multiple aberrant crypt foci and colorectal tumors from the same patients. (2001) (54)
- Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer (2013) (54)
- Regulation of MMP-9 (type IV collagenase) production and invasiveness in gliomas by the extracellular signal-regulated kinase and jun amino-terminal kinase signaling cascades (2004) (54)
- Downregulation of uPA/uPAR inhibits intermittent hypoxia-induced epithelial-mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells. (2011) (54)
- CpG island promoter methylation and silencing of 14-3-3σ gene expression in LNCaP and Tramp-C1 prostate cancer cell lines is associated with methyl-CpG-binding protein MBD2 (2006) (53)
- Suppression of tumor cell invasiveness and in vivo tumor growth by microRNA-874 in non-small cell lung cancer. (2013) (53)
- Down-regulation of Integrin αvβ3 Expression and Integrin-mediated Signaling in Glioma Cells by Adenovirus-mediated Transfer of Antisense Urokinase-type Plasminogen Activator Receptor (uPAR) and Sense p16 Genes* (2001) (53)
- Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression. (2013) (53)
- uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo. (2008) (52)
- Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells. (2005) (52)
- Restoration of Tissue Factor Pathway Inhibitor-2 in a Human Glioblastoma Cell Line Triggers Caspase-Mediated Pathway and Apoptosis (2007) (51)
- Urokinase-type Plasminogen Activator Receptor (uPAR)-mediated Regulation of WNT/β-Catenin Signaling Is Enhanced in Irradiated Medulloblastoma Cells* (2012) (51)
- Cathepsin B and uPAR Knockdown Inhibits Tumor-induced Angiogenesis by Modulating VEGF Expression in Glioma (2011) (50)
- Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT. (2011) (50)
- Immunohistochemical Localization of Plasminogen Activator Inhibitor Type 1 in Human Brain Tumors (1994) (50)
- Elevated levels of M(r) 92,000 type IV collagenase during tumor growth in vivo (1998) (50)
- N-cadherin mediates angiogenesis by regulating monocyte chemoattractant protein-1 expression via PI3K/Akt signaling in prostate cancer cells. (2011) (49)
- Expression of cathepsin D during the progression of human gliomas (1996) (49)
- The hemopexin domain of MMP‐9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice (2009) (47)
- SPARC stimulates neuronal differentiation of medulloblastoma cells via the Notch1/STAT3 pathway. (2011) (47)
- Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines. (2001) (45)
- Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using anin vitro Matrigel model (2005) (45)
- Expression and cellular localization of messenger RNA for plasminogen activator inhibitor type 1 in human astrocytomas in vivo. (1994) (45)
- MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line (2007) (45)
- Prognostic significance of proteolytic enzymes in human brain tumors (2005) (45)
- Induction of tissue‐type plasminogen activator and 72‐kDa type‐IV collagenase by ionizing radiation in rat astrocytes (1994) (45)
- The role of MMP-9 in the anti-angiogenic effect of secreted protein acidic and rich in cysteine (2010) (44)
- MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumors (2011) (44)
- MMP-9 and uPAR regulated glioma cell migration (2012) (44)
- Suppression of uPA and uPAR Attenuates Angiogenin Mediated Angiogenesis in Endothelial and Glioblastoma Cell Lines (2010) (43)
- MMP-9 short interfering RNA induced senescence resulting in inhibition of medulloblastoma growth via p16(INK4a) and mitogen-activated protein kinase pathway. (2007) (43)
- Effects of radiation on the levels of MMP‐2, MMP‐9 and TIMP‐1 during morphogenic glial‐endothelial cell interactions (2000) (42)
- MMP-9, uPAR and Cathepsin B Silencing Downregulate Integrins in Human Glioma Xenograft Cells In Vitro and In Vivo in Nude Mice (2010) (42)
- Restoration of tissue factor pathway inhibitor inhibits invasion and tumor growth in vitro and in vivo in a malignant meningioma cell line. (2006) (41)
- Modulation of invasive properties of human glioblastoma cells stably expressing amino-terminal fragment of urokinase-type plasminogen activator (2002) (40)
- Biological significance of the expression of urokinase-type plasminogen activator receptors (uPARs) in brain tumors. (1999) (40)
- Expression of matrix metalloproteinases, their inhibitors, and urokinase plasminogen activator in human meningiomas. (2003) (40)
- Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells. (2010) (40)
- RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth. (2006) (39)
- Human umbilical cord blood stem cells show PDGF-D-dependent glioma cell tropism in vitro and in vivo. (2010) (39)
- Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB. (2008) (39)
- Transfection with Anti-p65 Intrabody Suppresses Invasion and Angiogenesis in Glioma Cells by Blocking Nuclear Factor-κB Transcriptional Activity (2007) (38)
- In vitro modulation of human lung cancer cell line invasiveness by antisense cDNA of tissue factor pathway inhibitor-2 (2004) (38)
- Role of tissue factor pathway inhibitor-2 (TFPI-2) in amelanotic melanoma (C-32) invasion (2004) (38)
- Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors (1998) (38)
- Frequent Loss of Cystatin E/M Expression Implicated in the Progression of Prostate Cancer (2009) (38)
- Role of extracellular matrix proteins in regulation of human glioma cell invasion in vitro (1996) (37)
- Matrix metalloproteinase-9 Inhibition Down-Regulates Radiation-Induced Nuclear Factor-κB Activity Leading to Apoptosis in Breast Tumors (2008) (37)
- Elevated levels of cathepsin B in human glioblastoma cell lines. (2001) (37)
- Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells. (2001) (36)
- Matrix localization of tissue factor pathway inhibitor-2/matrix-associated serine protease inhibitor (TFPI-2/MSPI) involves arginine-mediated ionic interactions with heparin and dermatan sulfate: heparin accelerates the activity of TFPI-2/MSPI toward plasmin. (1999) (36)
- uPAR and cathepsin B inhibition enhanced radiation-induced apoptosis in gliomainitiating cells. (2012) (35)
- Extracellular matrix (ECM) synthesis in muscle cell cultures: quantitative and qualitative studies during myogenesis. (1985) (35)
- Plasminogen activator inhibitor-1 in brain tumors: relation to malignancy and necrosis. (1995) (34)
- Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases. (2009) (34)
- Suppression of glioma invasion and growth by adenovirus-mediated delivery of a bicistronic construct containing antisense uPAR and sense p16 gene sequences (2002) (34)
- Serine proteases and serpins: their possible roles in the motor system. (1988) (34)
- Elevated levels of Mr 92,000 type IV collagenase during tumor growth in vivo. (1998) (33)
- Cytogenetic and molecular abnormalities in astrocytic gliomas (Review). (2000) (33)
- The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma (2012) (32)
- Small Interfering RNA–Directed Knockdown of Uracil DNA Glycosylase Induces Apoptosis and Sensitizes Human Prostate Cancer Cells to Genotoxic Stress (2009) (32)
- Co-Depletion of Cathepsin B and uPAR Induces G0/G1 Arrest in Glioma via FOXO3a Mediated p27Kip1 Upregulation (2010) (32)
- Proteolysis and invasiveness of brain tumors: Role of urokinase-type plasminogen activator receptor (1994) (32)
- Integrin α9β1-mediated cell migration in glioblastoma via SSAT and Kir4.2 potassium channel pathway. (2012) (32)
- Downregulation of Focal Adhesion Kinase (FAK) by cord blood stem cells inhibits angiogenesis in glioblastoma (2010) (31)
- Selective inhibition of factor Xa is more efficient than factor VIIa-tissue factor complex blockade at facilitating coronary thrombolysis in the canine model. (1996) (31)
- Neuronal Apoptosis Is Inhibited by Cord Blood Stem Cells after Spinal Cord Injury (2009) (31)
- Knockdown of cathepsin B and uPAR inhibits CD151 and α3β1 integrin‐mediated cell adhesion and invasion in glioma (2012) (31)
- Modulation of endothelial cell morphogenesis in vitro by MMP-9 during glial-endothelial cell interactions* (2004) (31)
- A novel role for the urokinase-type plasminogen activator receptor in apoptosis of malignant gliomas. (2000) (31)
- Drugs in preclinical and early-stage clinical development for pancreatic cancer (2012) (31)
- Triterpenoids from Glycine max decrease invasiveness and induce caspase-mediated cell death in human SNB19 glioma cells (2003) (30)
- Notch signaling regulates tumor-induced angiogenesis in SPARC-overexpressed neuroblastoma (2012) (30)
- RNA interference–mediated simultaneous down-regulation of urokinase-type plasminogen activator receptor and cathepsin B induces caspase-8–mediated apoptosis in SNB19 human glioma cells (2006) (30)
- Altered in vitro spreading and cytoskeletal organization in human glioma cells by downregulation of urokinase receptor (1997) (30)
- uPAR and cathepsin B shRNA impedes TGF-β1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway (2012) (29)
- Expression of cysteine protease inhibitors in human gliomas and meningiomas (1996) (29)
- Suppression of MMP-2 Attenuates TNF-α Induced NF-κB Activation and Leads to JNK Mediated Cell Death in Glioma (2011) (29)
- Serpin inhibitors of urokinase and thrombin in normal rat brain and the 9L brain tumor: evidence for elevated expression of protease nexin I-like inhibitor and a novel sodium dodecyl sulfate-activated tumor antithrombin. (1990) (28)
- A novel role of tissue factor pathway inhibitor-2 in apoptosis of malignant human gliomas. (2001) (28)
- uPA and uPAR shRNA inhibit angiogenesis via enhanced secretion of SVEGFR1 independent of GM‐CSF but dependent on TIMP‐1 in endothelial and glioblastoma cells (2012) (28)
- Epigenetic Upregulation of Urokinase Plasminogen Activator Promotes the Tropism of Mesenchymal Stem Cells for Tumor Cells (2010) (28)
- Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: Modulation of migration and invasion of human malignant glioma cells (1999) (27)
- Modulation of matrix metalloprotease-2 and invasion in human glioma cells by alpha 3 beta 1 integrin. (1996) (27)
- Rapid neural regulation of muscle urokinase-like plasminogen activator as defined by nerve crush. (1990) (27)
- Downregulation of urokinase-type plasminogen activator receptor (uPAR) induces caspase-mediated cell death in human glioblastoma cells (2000) (27)
- Growth characteristics of glioblastoma spheroids. (2001) (27)
- RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer's brain synaptosomes (2013) (27)
- Apoptosis Induced by Knockdown of uPAR and MMP-9 is Mediated by Inactivation of EGFR/STAT3 Signaling in Medulloblastoma (2012) (27)
- Suppression of uPA and uPAR blocks radiation-induced MCP-1 mediated recruitment of endothelial cells in meningioma. (2011) (26)
- Protease nexin I, thrombin‐ and urokinase‐inhibiting serpin, concentrated in normal human cerebrospinal fluid (1992) (26)
- Urokinase Plasminogen Activator Receptor and/or Matrix Metalloproteinase-9 Inhibition Induces Apoptosis Signaling through Lipid Rafts in Glioblastoma Xenograft Cells (2010) (26)
- Doxorubicin-mediated apoptosis in glioma cells requires NFAT3 (2009) (26)
- Activities, localizations, and roles of serine proteases and their inhibitors in human brain tumor progression (2005) (26)
- Matrix metalloproteinase pharmacogenomics in non-small-cell lung carcinoma. (2011) (25)
- RNA interference-mediated targeting of urokinase plasminogen activator receptor and matrix metalloproteinase-9 gene expression in the IOMM-lee malignant meningioma cell line inhibits tumor growth, tumor cell invasion and angiogenesis. (2007) (25)
- Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo. (2011) (25)
- Regulation of the urokinase-type plasminogen activator receptor gene in different grades of human glioma cell lines. (2001) (25)
- RNAi-mediated downregulation of radiation-induced MMP-9 leads to apoptosis via activation of ERK and Akt in IOMM-Lee cells. (2009) (25)
- Plasminogen activator inhibitor 1, the primary regulator of fibrinolysis, in normal human cerebrospinal fluid (1993) (25)
- Regulation of Glioblastoma Progression by Cord Blood Stem Cells Is Mediated by Downregulation of Cyclin D1 (2011) (24)
- SPARC Overexpression Inhibits Cell Proliferation in Neuroblastoma and Is Partly Mediated by Tumor Suppressor Protein PTEN and AKT (2012) (24)
- uPAR and cathepsin B-mediated compartmentalization of JNK regulates the migration of glioma-initiating cells☆ (2014) (24)
- Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model. (2008) (24)
- Collagenase activity in skin fibroblasts of patients with amyotrophic lateral sclerosis (1986) (24)
- Plasminogen activators and their inhibitors in the neuromuscular system: II. Serpins and serpin: Protease complex receptors increase during in vitro myogenesis (1990) (23)
- Neuronal apoptosis is inhibited by cord blood stem cells after spinal cord injury. (2009) (23)
- RNAi-mediated downregulation of MMP-2 activates the extrinsic apoptotic pathway in human glioma xenograft cells. (2008) (23)
- Tumor-associated soluble uPAR-directed endothelial cell motility and tumor angiogenesis (2013) (23)
- MMP-2 downregulation mediates differential regulation of cell death via ErbB-2 in glioma xenografts. (2009) (22)
- uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells (2012) (21)
- Elevated levels of urokinase-type plasminogen activator and its receptor during tumor growth in vivo. (1999) (21)
- Regulation of the uPA gene in various grades of human glioma cells. (2001) (21)
- Down-regulation of uPAR and cathepsin B retards cofilin dephosphorylation. (2006) (20)
- Regulation of DNA Repair Mechanism in Human Glioma Xenograft Cells both In Vitro and In Vivo in Nude Mice (2011) (20)
- MMP-2 suppression abrogates irradiation-induced microtubule formation in endothelial cells by inhibiting αvβ3-mediated SDF-1/CXCR4 signaling (2013) (20)
- Activation of caspase-9 with irradiation inhibits invasion and angiogenesis in SNB19 human glioma cells (2004) (20)
- Increased levels of plasminogen activator inhibitor-1 (PAI-1) in human brain tumors (1993) (19)
- α3β1 integrin promotes radiation-induced migration of meningioma cells. (2011) (19)
- MMP-9 silencing regulates hTERT expression via β1 integrin-mediated FAK signaling and induces senescence in glioma xenograft cells. (2011) (19)
- Stem Cells Downregulate the Elevated Levels of Tissue Plasminogen Activator in Rats After Spinal Cord Injury (2009) (19)
- Plasminogen activator inhibitor-1 in the pathogenesis of delayed radiation damage in rat spinal cord in vivo. (1994) (19)
- Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration (2013) (19)
- Extracellular-matrix synthesis by skeletal muscle in culture. Major secreted collagenous proteins of clonal myoblasts. (1985) (18)
- Developmental appearance of thrombospondin in neonatal mouse skeletal muscle. (1991) (18)
- The effect of type III collagen on migration and invasion of human glioblastoma cell lines in vitro. (1996) (18)
- Plasminogen activators and their inhibitors in the neuromuscular system: I. Developmental regulation of plasminogen activator isoforms during in vitro myogenesis in two cell lines (1990) (18)
- uPAR and cathepsin B downregulation induces apoptosis by targeting calcineurin A to BAD via Bcl-2 in glioma (2011) (17)
- Expression of 72 kDa and 92 kDa type IV collagenases from human giant-cell tumor of bone (1995) (17)
- Glioma cells deficient in urokinase plaminogen activator receptor expression are susceptible to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis. (2001) (17)
- Human umbilical cord blood derived stem cells repair doxorubicin-induced pathological cardiac hypertrophy in mice. (2010) (17)
- Modulation of Serine Proteinases and Metalloproteinases During Morphogenic Glial‐Endothelial Interactions (1996) (17)
- siRNA-Mediated Downregulation of MMP-9 and uPAR in Combination with Radiation Induces G2/M Cell-Cycle Arrest in Medulloblastoma (2010) (17)
- Induction of apoptosis in glioma cells requires cell-to-cell contact with human umbilical cord blood stem cells. (2010) (16)
- Downregulation of the urokinase-type plasminogen activator receptor through inhibition of translation by antisense oligonucleotide suppresses invasion of human glioblastoma cells (1999) (16)
- Radiation-induced hypomethylation triggers urokinase plasminogen activator transcription in meningioma cells. (2013) (15)
- Simultaneous downregulation of uPAR and MMP-9 induces overexpression of the FADD-associated protein RIP and activates caspase 9-mediated apoptosis in gliomas. (2008) (15)
- Regulation of MMP-9 (92 kDa type IV collagenase/gelatinase B) expression in stromal cells of human giant cell tumor of bone (1997) (15)
- Erratum: Regulation of ProMMP-1 and ProMMP-3 activation by tissue factor pathway inhibitor-2/matrix-associated serine protease inhibitor (Biochemical and Biophysical Research Communications (1999) 255, 1 (94-98)) (1999) (15)
- Effect of cisplatin and BCNU on MMP-2 levels in human glioblastoma cell lines in vitro (1997) (15)
- uPAR/Cathepsin B Overexpression Reverse Angiogenesis by Rescuing FAK Phosphorylation in uPAR/Cathepsin B Down Regulated Meningioma (2011) (15)
- Radiation-inducible silencing of uPA and uPAR in vitro and in vivo in meningioma. (2010) (14)
- Increased invasion of neuroglioma cells transfected with urokinase plasminogen activator receptor cDNA. (1998) (14)
- Thrombospondin, a platelet α-granule and matrix glycoprotein, is increased in muscle basement membrane of patients with amyotrophic lateral sclerosis (1992) (14)
- Transcriptional repression of Mad-Max complex by human umbilical cord blood stem cells downregulates extracellular signal-regulated kinase in glioblastoma. (2012) (14)
- Regulation of proteases after spinal cord injury. (2012) (13)
- p53 enhances the Δ-24 conditionally replicative adenovirus anti-glioma effect (2006) (13)
- Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas (2002) (13)
- Physiological and chemical inducers of tissue factor pathway inhibitor-2 in human glioma cells. (2003) (13)
- Proteoglycan synthesis by clonal skeletal muscle cells during in vitro myogenesis: Differences detected in the types and patterns from primary cultures (1991) (12)
- Human umbilical cord blood-derived mesenchymal stem cells upregulate myelin basic protein in shiverer mice. (2011) (12)
- Elevated levels of plasminogen activators in the pathogenesis of delayed radiation damage in rat cervical spinal cord in vivo. (1994) (11)
- p53 enhances the Delta-24 conditionally replicative adenovirus anti-glioma effect. (2006) (11)
- Mechanism of p27 upregulation induced by downregulation of cathepsin B and uPAR in glioma (2011) (11)
- The homing of human cord blood stem cells to sites of inflammation (2012) (11)
- Characterization of the Serpin, α1‐Antichymotrypsin, in Normal Human Cerebrospinal Fluid (1992) (10)
- Modulation of fibrinolysis by ionizing radiation (2005) (10)
- Metabolic remodeling precedes mitochondrial outer membrane permeabilization in human glioma xenograft cells. (2011) (10)
- Proteoglycan synthesis by primary chick skeletal muscle during in vitro myogenesis (1987) (10)
- Effect of human umbilical cord blood cells on Ang-II-induced hypertrophy in mice. (2009) (10)
- Bortezomib Sensitizes Human Astrocytoma Cells to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis (2007) (9)
- Sense p16 and antisense uPAR bicistronic construct inhibits angiogenesis and induces glioma cell death. (2007) (9)
- Prognostic factors in multifocal gliomas: in regard to Showalter et al. (Int J Radiat Oncol Biol Phys 2007;69:820-824). (2007) (7)
- Invasive pattern of lac-Z-transfected human glioblastoma cells in nude mice brain. (1996) (7)
- Decreased levels of glia-derived nexin/protease nexin I in irradiated rat spinal cord in vivo. (1993) (7)
- Glial cell-induced endothelial morphogenesis is inhibited by interfering with extracellular signal-regulated kinase signaling. (2003) (7)
- A Cascade Approach to Synapse Formation Based on Thrombogenic and Fibrinolytic Models (1990) (7)
- Matrix metalloproteinase-1 (MMP-1) expression and biological significance in the progression of prostate cancer (2007) (6)
- Thrombospondin, a platelet alpha-granule and matrix glycoprotein, is increased in muscle basement membrane of patients with amyotrophic lateral sclerosis. (1992) (5)
- Correction: Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas (2014) (5)
- Nuclear Translocation of Hand-1 Acts as a Molecular Switch to Regulate Vascular Radiosensitivity in Medulloblastoma Tumors: The Protein uPAR Is a Cytoplasmic Sequestration Factor for Hand-1 (2014) (5)
- Role and Regulation of Proteases in Human Glioma (2005) (4)
- Bortezomib Sensitizes Human Astrocytoma Cells to Tumor Necrosis Factor-Related Apoptosis-lnducing Ligand : Induced Apoptosis. Authors' reply (2007) (4)
- Plasminogen Activators in Development, Injury and Pathology of the Neuromuscular System (1990) (4)
- Expression and localization of urokinase-type plasminogen activator in human spinal column tumors (1998) (4)
- Design, synthesis and preclinical evaluation of NRC-AN-019. (2013) (3)
- Matrix metalloproteinases: Regulation and biological functions (1999) (3)
- Abstract 420: Critical role of MMP-2 and GATA-1 nuclear interaction in the regulation of ionizing radiation (IR)-induced IL-10/Stat3-mediated invasion and migration in glioblastoma. (2013) (3)
- Abstract 3099: Radiation-induced angiogenesis is associated with MMP-9-miR-494-Syndecan-1 regulatory loop in medulloblastoma cells. (2013) (3)
- Temozolomide and resistant glioma cells. (2008) (2)
- 1 Brain Tumor Angiogenesis (2009) (2)
- Angiogenesis , and Tumor Growth Glioblastoma Cells Efficiently Inhibits Glioma Cell Invasion , Activator Receptor and Matrix Metalloproteinase-9 in SNB 19 Synergistic Down-Regulation of Urokinase Plasminogen (2003) (2)
- Restoration of TFPI-2 in a human glioblastoma cell line triggers caspase mediated pathway and apoptosis (2007) (2)
- Downregulation of integrin α v β 3 expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense uPAR and sense p 16 genes (2001) (2)
- Radio-responsive TRAIL gene therapy for malignant gliomas (2007) (1)
- Erratum: Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas (PLoS ONE (2014) 9:1 (DOI:10.1371/annotation/bb2f92ec-2ac1-4952-b744- 0519aeb10d1c)) (2014) (1)
- Retraction: Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas. (2020) (1)
- Oncogenic role of p 53 is suppressed by siRNA bicistronic construct of uPA , uPAR and cathepsin-B in meningiomas both in vitro and in vivo (1)
- Inhibition of lung cancer cell invasion and metastasis by RNAi-mediated downregulation of urokinase plasminogen activator and its receptor. (2004) (1)
- Abstract 475: uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton and migration of glioma initiating cells (2012) (1)
- Abstract 2617: uPAR and cathepsin B knockdown-induced nuclear translocation of JNK inhibits migration and induces apoptosis in glioma-initiating cells. (2013) (1)
- Retraction: SPARC Overexpression Inhibits Cell Proliferation in Neuroblastoma and Is Partly Mediated by Tumor Suppressor Protein PTEN and AKT (2020) (1)
- Antitumor activity of NRC-AN-019 in a pre-clinical breast cancer model. (2011) (1)
- Notch signaling regulates tumor-induced angiogenesis in SPARC-overexpressed neuroblastoma (2012) (1)
- ROLE AND REGULATION OF MATRIX METALLOPROTEASES IN BRAIN TUMOURS (2005) (1)
- Meningioma: Urokinase Plasminogen Activator (2012) (1)
- Mesenchymal Stem Cell Therapy for Apoptosis After Spinal Cord Injury (2011) (1)
- Abstract 2218: Radiation-induced hypomethylation triggers urokinase plasminogen activator (uPA) transcription in meningioma cells (2012) (1)
- Tumor Growth and Metastasis Plasminogen Activator Demethylation Inhibits Prostate Directed Reversal of Urokinase − Small Interfering RNA (2007) (1)
- Abstract 2286: SPARC stimulates neuronal differentiation of medulloblastoma cells via the IL-6/STAT3 pathway (2010) (1)
- Corrigendum: 'Expression and the role of cathepsin H in human glioma progression and invasion' (Cancer Letters (1996) 104 (121-126)) (1996) (1)
- Abstract 4992: SPARC overexpression induces ER stress leading to autophagy-mediated apoptosis in neuroblastoma cells (2012) (1)
- Corrigendum to “Chk2-mediated G2/M cell cycle arrest maintains radiation resistance in malignant meningioma cells” [Cancer Lett. 313 (1) (2011) 64–75] (2014) (1)
- Cisplatin but not BCNU inhibits urokinase-type plasminogen activator levels in human glioblastoma cell lines in vitro (1997) (0)
- Withdrawal: Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of β1-integrin, ERK, and NF-κB. (2020) (0)
- Erratum: Enforced expression of wild-type p53 curtails the transcription of the O6-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents (Clinical Cancer Research (May 1, 2001) 7 (1398-1409)) (2005) (0)
- 18 Mesenchymal Stem Cell Therapy for Apoptosis After Spinal Cord Injury (2017) (0)
- Abstract 223: Targeting PDK-1 and EGFR by human umbilical cord blood stem cells reverses Warburg effect in glioblastoma multiforme. (2013) (0)
- Abstract 5277: MMP-2 suppression abrogates irradiation-induced microtubule formation in endothelial cells by inhibiting αvβ3-mediated SDF-1/CXCR4 signaling (2012) (0)
- Correction: Article on the Enforced Expression of Wild-Type p53 and the Transcription of the O6-Methylguanine-DNA Methyltransferase Gene (2005) (0)
- Corrigendum: Modulation of matrix metalloprotease-2 and invasion in human glioma cells by α3β1 integrin (Cancer Letters (1996) 103 (201-208)) (1997) (0)
- ugh Lipid Rafts in Glioblastoma Xenograft Cells (2010) (0)
- Abstract #2307: Expression of hemopexin domain of MMP-9 sensitizes resistant glioblastoma cells to radiation therapy (2009) (0)
- Human Umbilical Cord Stem Cells Regulate the Surrounding Microenvironment through Active Secretion of Signaling Molecules (2012) (0)
- YKL-40 andMatrix Metalloproteinase-9 as Potential Serum Biomarkers for Patients with High-Grade Gliomas (2006) (0)
- Abstract 3468: MMP-9 inhibition abolishes hypoxia-induced angiogenesis in medulloblastoma (2011) (0)
- Abstract 3046: Cathepsin B and uPAR downregulation sensitizes glioma initiating cells to radiation induced cell cycle arrest (2012) (0)
- Expression and biological significance of tissue inhibitors of metalloproteinases (1999) (0)
- Influence of tumor-conditioned medium on hypoxia-mediated inhibition of growth and survival of endothelial cells (2006) (0)
- Effect of specific siRNA targeting uPAR and MMP-9 in medulloblastoma (2006) (0)
- Effects of promoter methylation on tissue inhibitor of metalloproteinases-2 (TIMP-2) expression in prostate cancer (2006) (0)
- Retraction: Down-regulation of integrin αvβ3 expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense urokinase-type plasminogen activator receptor (uPAR) and sense p16 genes. (2020) (0)
- Abstract 2635: Galectin-1 modulates glioblastoma cell migration via interaction with FAK. (2013) (0)
- Transfection with anti-p65 intrabody suppresses invasion, metastasis, and angiogenesis in glioma cells by blocking NF-κβ transcriptional activity (2006) (0)
- enetic Upregulation of Urokinase Plasminogen Activator motes the Tropism of Mesenchymal Stem Cells for R or Cells (2010) (0)
- Abstract 3323: Induction of apoptosis in glioma cells by downregulation of X-linked inhibitor of apoptosis protein (XIAP) (2010) (0)
- Abstract 3635: Novel chemotherapeutic agent AN019 for lapatinib-resistant breast cancer (2010) (0)
- Corrigendum to “Effect of human umbilical cord blood cells on Ang-II-induced hypertrophy in mice” [Biochem. Biophys. Res. Commun. 386 (2009) 386–391] (2012) (0)
- Abstract 510: Intermittent hypoxia confers resistance to radiation in human neuroblastoma cells (2010) (0)
- Abstract 240: Transcriptional knockdown of urokinase-type plasminogen activator receptor (uPAR) induces apoptosis in glioblastoma xenograft cells via activation of p53 (2012) (0)
- Intermittent hypoxia enhances survival of human neuroblastoma cells (2008) (0)
- Role of Naïve Cord Blood Stem Cells in Glioma Therapy (2013) (0)
- Abstract 5503: Anti-proliferative role of MMP-9 and uPAR/cathepsin B knockdown in negative regulation of DNA repair mechanisms in human glioma xenografts (2011) (0)
- Abstract 1493: Tumor-associated soluble uPAR enhances endothelial cell migration by staffing into lipid rafts (2011) (0)
- Abstract 136: Suppression of the uPA/uPAR system causes the overexpression of miR124 and suppresses stemness in glioma stem cells (2012) (0)
- Abstract #2304: Effects of reirradiation on human glioblastoma cells previously treated with low dose fractionated radiotherapy (2009) (0)
- Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo (2021) (0)
- Adenovirus-mediated transfer of siRNAs against MMP-2 mRNA results in impaired growth, invasion and migration of glioblastoma cells as well as inhibition of tumor-induced angiogenesis (2007) (0)
- Abstract 592: Downregulation of uPAR and uPA retards angiogenesis and proliferation and activates the extrinsic apoptotic pathway in pancreatic cancer cells (2010) (0)
- Retraction: RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo. (2020) (0)
- Abstract 408: Intermittent hypoxia effect on osteoclastogenesis stimulated by neuroblastoma cells (2012) (0)
- Retraction Note to: uPAR and cathepsin B downregulation induces apoptosis by targeting calcineurin A to BAD via Bcl-2 in glioma (2021) (0)
- Advances in Brief Selective Suppression of Matrix Metalloproteinase-9 in Human Glioblastoma Cells by Antisense Gene Transfer Impairs Glioblastoma Cell Invasion 1 (2000) (0)
- Abstract 3393: Extrinsic uPA initiates glioma stem cell transformation under hypoxic conditions via Lhx-2 (2011) (0)
- Abstract 4060: Radiation-inducible silencing of uPA and uPARin vitroandin vivoin meningioma (2010) (0)
- Abstract 1322: Sensitizing radiation-induced integrin β-1 signaling by targeting uPAR in medulloblastoma cells (2010) (0)
- Serpins and Brain Tumors: Roles in Pathogenesis (1990) (0)
- Abstract 576: Gadd45a sensitizes medulloblastoma cells to irradiation and modulates the cellular switch from migratory to stationary cell phase by downregulating MMP-9 (2011) (0)
- Abstract 2456: External uPA overexpresses and interacts with Lhx-2 and induces a pancreatic cancer stem cell phenotype (2011) (0)
- Nuclear translocation of Hand-1 acts as a molecular switch to regulate vascular radiosensitivity in MB tumors : The protein uPAR is a cytoplasmic sequestration factor for Hand-1 (2014) (0)
- Abstract 3904: uPAR-regulated nuclear translocation of hand-1 mediates vascular radiosensitivity in medulloblastoma tumors. (2013) (0)
- Invasiveness of Human Glioma Stem Cells Controlled by Cord Blood Stem Cells Via Regulation of Integrin α6, N-cadherin, and Erk Interactions (2012) (0)
- Abstract 3453: SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT (2012) (0)
- Abstract 3947: Radiation treatment solubilizes membrane receptors in meningioma cells (2014) (0)
- Abstract 1118: Protease-integrin regulates mitochondrial biogenesis in glioma xenograft cells (2012) (0)
- Experiment K-7-29: Connective Tissue Studies. Part 1; Rat Skin, Normal and Repair (1994) (0)
- Experiment K-7-29: Connective Tissue Studies. Part 2; Changes in Muscle Serine Proteases, Serpins and Matrix Molecules (1994) (0)
- Enhanced response of radiation via the adenovirus-mediated transfer of antisense MMP-9 in a breast cancer tumor model (2006) (0)
- Abstracts for the Tenth International Conference on Brain Tumour Research and Therapy (2005) (0)
- Inducible Nitric Oxide Synthase ( iNOS ) Is Expressed Similarly in Multiple Aberrant Crypt Foci and Colorectal Tumors from the Same Patients 1 (2001) (0)
- Abstract 2389: uPA and uPAR siRNA inhibits angiogenesis by blocking nuclear localization of angiogenin and angiopoietin1 signaling in glioblastoma cell lines (2010) (0)
- Abstract 3070: Suppression of tumor cell invasiveness andin vivotumor growth by microRNA-874 in non-small cell lung cancer. (2013) (0)
- Abstract 572: Suppression of urokinase plasminogen activator receptor blocks recruitment of endothelial cells by inhibiting irradiation-induced monocyte chemo-attractant protein-1 in meningioma (2011) (0)
- Abstract 2771: Genetic variation in interleukin, TLR, TNF and TRAF genes of NF-κB activation pathway and risk of prostate cancer (2011) (0)
- Abstract 3376: Cord blood stem cells revert EMT to MET in glioma stem cells by downregulating synergistic transcriptional activation of Sox2 and Twist1 (2012) (0)
- Urokinase-type Plasminogen Activator Receptor Antibody Invasion of Human Glioblastoma Cells by in Vitro Modulation of Updated (2006) (0)
- A longitudinal prospective study of YKL-40 and matrix metalloproteinase-9 (MMP-9) as serum tumor markers in gliomas (2008) (0)
- Abstract 1294: Suppression of uPA in chemo-sensitization and p53 regulation in pancreatic cancer cells (2012) (0)
- Abstract 3870: Overexpression of SPARC represses MMP-9 mediated metastasis in neuroblastoma. (2013) (0)
- Abstract 2055: Influence of intermittent hypoxia on differentiation in neuroblastoma (2011) (0)
- Abstract 5219: MicroRNA-874 impedes angiogenesis in non-small cell lung cancer (2014) (0)
- Abstract 1313: SPARC enhances radiosensitivity by inhibiting radiation-induced SOX-4 transcription factor in medulloblastoma (2010) (0)
- Abstract 3020: The role of NF-κB (p65) and Stat3 interplay in the regulation of radiation-induced, ICAM-1-mediated migration and invasion in glioma (2012) (0)
- Abstract 2085: MMP-2 knockdown leads to anoikis and inhibits migration and invasion by attenuating αvβ3/EGFR/Pak4 survival signaling in human glioma xenograft cellsin vitroandin vivo (2012) (0)
- Abstract 2938: Inhibition of PI3K/AKT and MEK/ERK pathways act independently on p27 upregulation induced by downregulation of cathepsin B and uPAR in glioma (2011) (0)
- Abstract 3631: AN019, a potent anticancer agent, suppresses tumors, ErbB-2, and angiogenesis in pancreatic cancer cells (2010) (0)
- Abstract 3465: shRNA against uPA and uPAR enhances secretion of sVEGFr1 in tumor endothelial and glioblastoma cells independent of GMCSF (2011) (0)
- Abstract 5212: Irradiation-induced uPAR promotes stemness via Wnt/β-catenin signaling in medulloblastoma cells (2012) (0)
- Abstract 1391: Simultaneous knockdown of MMP-9 and uPAR/cathepsin B retards α9β1 integrin-mediated cell migration via SSAT and potassium channel pathway in glioma xenografts (2011) (0)
- Abstract 5320: miR-211 expression inhibits MMP-9-induced phenotype and tumor growth in lung adenocarcinoma cancer stem cellsin vitroandin vivo. (2013) (0)
- Corrigendum to “Suppression of uPA and uPAR Blocks Radiation-induced MCP-1 mediated Recruitment of Endothelial Cells in meningioma” [Cell. Signal 23 (2011) 1299 -1310] (2013) (0)
- Abstract 2291: Downregulation of uPA/uPAR inhibits epithelial to mesenchymal transition (EMT) in intermittent hypoxic DAOY and D283 medulloblastoma cells (2010) (0)
- Abstract 5100: MMP-2 suppression inhibits α5β1 integrin and IL-3-mediated Stat5 activation and proliferation of endothelial cells. (2013) (0)
- Abstract 4986: Urokinase plasminogen activator (uPA) interacts with nuclear HOXA5 and inhibits p53 expression in glioma stem cells (2010) (0)
- Advances in Brief Elevated Levels of Mr 92 , 000 Type IV Collagenase in Human Brain Tumors 1 (2006) (0)
- Role of Urokinase-Type Plasminogen Activator Receptor in Human Glioma Invasion (2005) (0)
- Retraction: Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator. (2020) (0)
- Corrigendum to MMP-9 silencing regulates hTERT expression via β1 integrin-mediated FAK signaling and induces senescence in glioma xenograft cells [Cell. Signal. 23 (2011) 2065-2075] (2013) (0)
- Abstract 1529: Knockdown of cathepsin B and uPAR inhibits CD151 and α3β1 integrin-mediated cell adhesion in glioma (2011) (0)
- Abstract 4787: MMP-2 RNA interference leads to decreased NF-κB activation and induced JNK-mediated apoptosis by modulating TRADD-TRAF2-FADD interactions in glioma (2011) (0)
- Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration (2013) (0)
- Abstract 461: Involvement of α9β1 integrin-iNOS pathway in matrix metalloproteinase-9 and/or urokinase plasminogen activator receptor-mediated glioma cell migration (2012) (0)
- Abstract 4758: Self-assembled superparamagnetic iron oxide nanoparticles for targeted cancer therapy (2012) (0)
- Abstract 515: Interaction of CD44 with matrix metalloproteinase-9 (MMP-9) is crucial to maintain adhesion, migration and invasion in glioblastoma xenograft cells (2010) (0)
- Advances in Brief Modulation of in Vitro Invasion of Human Glioblastoma Cells by Urokinase-type Plasminogen Activator Receptor Antibody 1 (2006) (0)
- Abstract 1731: Decreased cyclin B1 expression contributes to mitochondrial apoptosis in medulloblastoma. (2013) (0)
- Therapeutic Potential of siRNA-mediated Targeting of Urokinase Plasminogen Activator (uPA), its Receptor (uPAR), and Matrix Metalloproteinases (MMPs) (2009) (0)
- Abstract 511: Integrin-mediated inhibition of adhesion, migration and invasion in glioma xenografts by MMP-9, uPAR and cathepsin B gene silencing (2010) (0)
- Advances in Brief-Catenin Expression Is Altered in Human Colonic Aberrant Crypt Foci 1 (2001) (0)
- Metabolic remodeling precedes mitochondrial outer membrane permeabilization in human glioma xenograft cells (2021) (0)
- Abstract 2330: MMP-2 regulates Rac1- and Cdc42-mediated cell migration via integrin αVβ3/FAK in U87 and U251 glioblastoma cell lines (2010) (0)
- SPARC Stimulates Neuronal Differentiation of Medulloblastoma Cells via the Notch1/Signal Transducer and Activator of Transcription 3 (STAT3) Pathway (2011) (0)
- Restoration of tissue factor pathway inhibitor inhibits invasion and tumor growth in a malignant meningioma cell line in vitro and in vivo (2004) (0)
- Experiment K-7-29: Connective Tissue Studies (2004) (0)
- α3β1 integrin promotes radiation-induced migration of meningioma cells (2021) (0)
- Abstract 3319: Cell cycle regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1 (2011) (0)
- Prognostic factors in multifocal gliomas : In regard to showalter et al. (int J radia T oncol biol phys 2007;69: 820-824). Authors' reply (2007) (0)
- Death , and Senescence siRNA-Mediated Downregulation of MMP-9 and uPAR in Combination with Radiation Induces G 2 / M Cell-Cycle Arrest in Medulloblastoma (2011) (0)
- Abstract 5187: Urokinase plasminogen activator receptor (uPAR) and integrin α5β1 regulate plasminogen activator inhibitor-1 (PAI-1) activity in medulloblastoma cells (2012) (0)
- Abstract 5369: AN019 in combination with ionizing radiation retards intracranial tumor growth and inhibits angiogenic inductionin vitroandin vivo (2010) (0)
- Abstract 434: Radiation-induced matrix metalloprotease-9 promotes mesenchymal transition of Daoy cells and initiates activation of pro-matrix metalloprotease-2. (2013) (0)
- “Small Interfering RNA (siRNA)-Directed Reversal of uPA Demethylation Inhibits Prostate Tumor Growth and Metastasis” (2007) (0)
- Inhibition of extracellular matrix (ECM) degradation by protease nexin I (PNI) in cultured muscle cells (1987) (0)
- Abstract 4907: Knockdown of MMP-9 inhibits radiation-induced invasive phenotype, angiogenesis and tumor growth in glioma cancer stem cells. (2013) (0)
- STAT3 activation promotes angiogenesis in human breast cancer cells (2008) (0)
- Abstract 5070: Cell-free endo180 reveals additional level of endocytic receptor functioning in meningioma. (2013) (0)
- MMP-2 downregulation abrogates radiation-induced G2-M arrest by inhibiting FoxM1 transcription factor mediated Chk2 and p53 expression (2008) (0)
- Advances in Brief Adenovirus-mediated Delivery of Antisense Gene to Urokinase-type Plasminogen Activator Receptor Suppresses Glioma Invasion and Tumor Growth 1 (1999) (0)
- Molecular Cancer apeutics linical Development kinase Plasminogen Activator Receptor and / or Matrix alloproteinase-9 Inhibition Induces Apoptosis Signaling Ther ugh Lipid Rafts in Glioblastoma Xenograft Cells (2010) (0)
- Retraction notice to "MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells" [Cellular Signaling (2012) 549-559]. (2021) (0)
- Temporal Regulation of Apoptotic and Anti-apoptotic Molecules After Middle Cerebral Artery Occlusion Followed by Reperfusion (2013) (0)
- Abstract 754: Nuclear liaison between PAK4 and PPARγ regulates radiation-induced MOX-1-mediated epithelial-mesenchymal transition and cell migration via a ROS-dependent mechanism in glioblastoma. (2013) (0)
- Abstract 3322: Downregulation of XIAP by cord blood stem cells is associated with inhibition of heat shock protein 90 in glioblastoma (2011) (0)
- Abstract 1278: Simultaneous downregulation of uPAR and cathepsin B inhibits angiogenesis and migration and induces caspase 8-mediated apoptosis in U87 stem cells and 4910 glioma xenograft stem cells (2010) (0)
- Abstract 1197: Soluble uPAR plays a critical role in the progression of meningioma by autocrine signaling (2012) (0)
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