Jayne S. Danska

Q: What Schools Are Affiliated With Jayne S. Danska

Jayne S. Danska is affiliated with the following schools: Yale University, University of Toronto

Jayne S. Danska's AcademicInfluence.com Rankings

Jayne S. Danska

Biology

#14803

World Rank

#18655

Historical Rank

Immunology

#1058

World Rank

#1084

Historical Rank

biology Degrees

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Biology

Why Is Jayne S. Danska Influential?

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According to Wikipedia, Jayne S. Danska is an immunologist in Canada. Danska is a Senior Scientist at the Hospital for Sick Children, a Professor at the University of Toronto's Faculty of Medicine, and the Anne and Max Tanenbaum Chair in Molecular Medicine.

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Jayne S. Danska's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity (2013) (1465)
Stem cell gene expression programs influence clinical outcome in human leukemia (2011) (916)
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice (1993) (575)
Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells (2007) (462)
V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors. (1996) (305)
Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes (1996) (197)
T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages (1990) (193)
The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides (1990) (180)
Opinion: Sex inclusion in basic research drives discovery (2015) (176)
SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin (2017) (155)
IL-4 expression at the onset of islet inflammation predicts nondestructive insulitis in nonobese diabetic mice. (1997) (144)
Rescue of T cell-specific V(D)J recombination in SCID mice by DNA-damaging agents. (1994) (130)
Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts (2012) (121)
Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells (2010) (108)
The Influence of the Microbiome on Type 1 Diabetes (2017) (105)
The intestinal microbiome in type 1 diabetes (2014) (93)
The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice. (2003) (87)
Metatranscriptomic analysis of diverse microbial communities reveals core metabolic pathways and microbiome-specific functionality (2016) (82)
Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway (1995) (82)
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. (2010) (80)
Independent genetic regulation of T-cell and antigen-presenting cell participation in autoimmune islet inflammation. (1998) (77)
Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis. (2000) (76)
ATM‐dependent DNA damage surveillance in T‐cell development and leukemogenesis: the DSB connection (2006) (75)
PIRs mediate innate myeloid cell memory to nonself MHC molecules (2020) (73)
Donor SIRPα polymorphism modulates the innate immune response to allogeneic grafts (2017) (72)
Cell Surface Profiling Using High-Throughput Flow Cytometry: A Platform for Biomarker Discovery and Analysis of Cellular Heterogeneity (2014) (71)
A diversified set of testicular cell proteins specified by genes within the mouse t complex (1983) (70)
SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells (2013) (69)
Microbiome manipulation modifies sex-specific risk for autoimmunity (2014) (61)
Modulation of type 1 and type 2 diabetes risk by the intestinal microbiome (2016) (60)
Relapse fated latent diagnosis subclones in acute B lineage leukaemia are drug tolerant and possess distinct metabolic programs. (2020) (59)
Immune recognition and response to the intestinal microbiome in type 1 diabetes. (2016) (58)
Generation and Analysis of a Mouse Intestinal Metatranscriptome through Illumina Based RNA-Sequencing (2012) (57)
γδ T Cells Are Essential Effectors of Type 1 Diabetes in the Nonobese Diabetic Mouse Model (2013) (56)
Development and function of diabetogenic T-cells in B-cell-deficient nonobese diabetic mice. (2001) (53)
ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes. (2007) (52)
Comparison of assembly algorithms for improving rate of metatranscriptomic functional annotation (2014) (47)
The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: a severe combined immune deficiency (SCID) murine model. (1997) (41)
Association of HLA-dependent islet autoimmunity with systemic antibody responses to intestinal commensal bacteria in children (2019) (40)
Sex-Specific Effect of Insulin-Dependent Diabetes 4 on Regulation of Diabetes Pathogenesis in the Nonobese Diabetic Mouse1 (2005) (37)
Immuno-ecology: how the microbiome regulates tolerance and autoimmunity. (2015) (36)
Susceptibility to lymphoid neoplasia in immunodeficient strains of nonobese diabetic mice. (2002) (35)
Peri-islet infiltrates of young non-obese diabetic mice display restricted TCR beta-chain diversity. (1995) (33)
Chromosomal reinsertion of broken RSS ends during T cell development (2007) (33)
Variation in the Cd3ζ (Cd247) Gene Correlates with Altered T Cell Activation and Is Associated with Autoimmune Diabetes (2010) (32)
Common ground: shared risk factors for type 1 diabetes and celiac disease (2018) (32)
American Diabetes Association and JDRF Research Symposium: Diabetes and the Microbiome (2015) (30)
Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia (2014) (30)
Sex Matters for Mechanism (2014) (29)
Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors. (1997) (27)
Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice (1996) (27)
Irradiation Promotes V(D)J Joining and RAG-Dependent Neoplastic Transformation in SCID T-Cell Precursors (2001) (27)
Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors. (2011) (24)
Polymorphism in the Innate Immune Receptor SIRPα Controls CD47 Binding and Autoimmunity in the Nonobese Diabetic Mouse (2014) (24)
Cell-free translation of a T t complex cell surface-associated gene product (1980) (20)
Genome-wide end-sequenced BAC resources for the NOD/MrkTac☆ and NOD/ShiLtJ☆☆ mouse genomes (2010) (19)
The Idd4 Locus Displays Sex-Specific Epistatic Effects on Type 1 Diabetes Susceptibility in Nonobese Diabetic Mice (2006) (19)
Genetic Control of T and B Lymphocyte Activation in Nonobese Diabetic Mice1 (2001) (17)
p53-Independent Apoptosis Disrupts Early Organogenesis in Embryos Lacking Both Ataxia-Telangiectasia Mutated and Prkdc (2006) (16)
B cell acute lymphoblastic leukemia cells mediate RANK-RANKL–dependent bone destruction (2020) (16)
Lck dependence of signaling pathways activated by γirradiation and CD3ε engagement in RAG-1-/-immature thymocytes (1996) (14)
Microvascular transplantation of physeal allografts. (1995) (13)
Limited T cell receptor beta-chain usage in the sperm whale myoglobin 110-121/E alpha dA beta d response by H-2d congenic mouse strains. (1992) (12)
Molecular Genetic Analysis of the Idd4 Locus Implicates the IFN Response in Type 1 Diabetes Susceptibility in Nonobese Diabetic Mice1 (2006) (11)
Maternal autoimmune thyroid disease and the fetal immune system. (2011) (11)
Structural similarity between a primitive chordate membrane heterodimer and lymphocyte antigen receptors. (1990) (9)
Induction of a heterogeneous TCR repertoire in (PL/JXSJL/J)F1 mice by myelin basic protein peptide Ac1-11 and its analog Ac1-11[4A]. (1997) (8)
gd T Cells Are Essential Effectors of Type 1 Diabetes in the Nonobese Diabetic Mouse Model (2013) (8)
The T cell receptor: structure, molecular diversity and somatic localization. (1989) (8)
Identification of the Inflammasome Nlrp1b as the Candidate Gene Conferring Diabetes Risk at the Idd4.1 Locus in the Nonobese Diabetic Mouse (2015) (8)
Lck dependence of signaling pathways activated by gamma-irradiation and CD3 epsilon engagement in RAG-1(-/-)-immature thymocytes. (1996) (6)
Restriction fragment-length polymorphism analysis of the major histocompatibility complex in New Zealand white rabbits. (1995) (6)
Abstract 5173: Genetic profiling of central nervous system dissemination of B-acute lymphoblastic leukemia reveals clonal selection and therapeutic vulnerability (2018) (5)
SIRPαFc treatment targets human acute myeloid leukemia stem cells (2019) (4)
MuLV-related endogenous retroviral elements and Flt3 participate in aberrant end-joining events that promote B-cell leukemogenesis (2014) (4)
Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target. (2021) (4)
Targeting SIRPα in cancer (2013) (4)
Defining Functional Heterogeneity In Acute Lymphoblastic Leukemia (2013) (3)
Metatranscriptomic analysis of diverse microbial communities reveals core metabolic pathways and microbiome-specific functionality (2016) (3)
Blockade Of CD47 Using SIRPαFc: Role Of The Fc Region In Anti-Leukemic Activity and Tolerability (2013) (3)
Beta-diversity distance matrices for microbiome sample size and power calculations — How to obtain good estimates (2022) (3)
RANK-RANKL Mediated Bone Destruction in B-Cell Acute Lymphoblastic Leukemia (2016) (2)
Analysis of the ternary complex of antigen, MHC and T-cell receptor: the influence of the T-cell receptor V beta repertoire on the V beta gene element usage. (1991) (2)
After the GWAS rush: nuggets of insight into the pathogenesis of autoimmune disease. (2009) (2)
Targeted blockade of immune mechanisms inhibit B precursor acute lymphoblastic leukemia cell invasion of the central nervous system. (2021) (2)
Bad to the bone: B cell acute lymphoblastic leukemia cells mediate bone destruction (2020) (2)
Evolution of the histocompatibility complex: Cloning and analysis of MHC related sequences in the colonial tunicate Botryllus sp. Monterey and the trout Salmo gairdneri (1986) (1)
Evolving heterogeneity in acute lymphoblastic leukemia (2014) (1)
Genetic Analysis of B-Cell Acute Lymphoblastic Leukemia Dissemination to the Central Nervous System Identifies Clonal Selection and Therapeutic Vulnerability (2018) (1)
Analysis of the ternary complex of antigen, MHC and T-cell receptor: the influence of the T-cell receptor Vβ repertoire on the Vβ gene element usage (1991) (1)
Comparison of assembly algorithms for improving rate of metatranscriptomic functional annotation (2014) (1)
Abstract 867: Therapeutic potential of small molecule SYK inhibitors for treatment of primary B cell acute lymphoblastic leukemia (2012) (1)
Sex Effects at the Ramparts: Nutrient- and Microbe-Mediated Regulation of the Immune-Metabolic Interface. (2017) (1)
Pathogenesis in the Nonobese Diabetic Mouse Diabetes 4 on Regulation of Diabetes Sex-Specific Effect of Insulin-Dependent (2005) (0)
MouseAutoimmunity in the Nonobese Diabetic Controls CD47 Binding and a Receptor SIRP Polymorphism in the Innate Immune (2014) (0)
Molecular probes for the genomic organization and evolution of the mouse t complex. (1983) (0)
DNA Repair and the Generation of Immune Diversity (2001) (0)
T Cells Involved in Inductive Events in the Pathogenesis of Autoimmune Diabetes Mellitus (1993) (0)
Diabetic Mouse Locus in the Nonobese Idd 4 . 1 Risk at the the Candidate Gene Conferring Diabetes as Nlrp 1 b Identification of the Inflammasome (2015) (0)
Kruppel-Like Factor, Klf9, Promotes Proliferation of Notch-Independent Precursor T-Cell Lymphoblastic Lymphomas (2012) (0)
Abstract A25: Evolving functional heterogeneity in B-acute lymphoblastic leukemia (2016) (0)
DNA Repair and the Generation of Immune Diversity The Agony and the Ecstasy (2001) (0)
SIRPFa treatment targets human acute myeloid leukemia stem cells (2020) (0)
Abstract 1397: A novel ligand-independent Flt3 allele drives RANKL expression in a murine model of B-precursor acute lymphoblastic leukemia with CNS dissemination (2012) (0)
Molecular Approaches to Histocompatibility in Colonial Tunicates (1988) (0)
Introduction: V(D)J recombination: a lymphocyte-specific process elaborates on an ancient repair machinery (1997) (0)
Acute Myeloid Leukemia Stem Cells Escape Innate Immune Surveillance by Macrophages through Interaction with SIRPα (2010) (0)
Human SIRPA Polymorphism Modulates Macrophage-Mediated Suppression of Human Hematopoiesis (2008) (0)
An alternative view of T-cell receptor-MHC interaction: T-cell receptor binds transversally to the alpha-helices of the MHC molecule. (1995) (0)
V ( D ) J recombination activates a . p 53-dependent DNA damage checkpoint m s c l d lymphocyte precursors (2007) (0)
Activation in Nonobese Diabetic Mice Genetic Control of T and B Lymphocyte (2001) (0)
Common ground: shared risk factors for type 1 diabetes and celiac disease (2018) (0)
Science Signaling Podcast: 19 February 2013 (2013) (0)
Polymorphic Prnp-flanking genes, but not Prnp itself, controls phagocytosis of apoptotic cells (2013) (0)
Role of Spleen Tyrosine Kinase Signaling in Early B Cell Acute Lymphoblastic Leukemia. (2009) (0)
A Novel Mutational Mechanism Drives Over-Expression of Ligand-Independent FLT3 in a Murine Model of B-Precursor ALL (2011) (0)
Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse (2016) (0)
This information is current as Diabetes The Influence of the Microbiome on Type 1 (2016) (0)
CD47-Sirpα Interaction Modulates Homing and Engraftment of Human Acute Myeloid Leukemia Stem Cells in Mice. (2009) (0)
Identification of a New Genetic Determinant Controlling Human Hematopoietic Stem Cell Engraftment. (2007) (0)
Mice Diabetes Susceptibility in Nonobese Diabetic Implicates the IFN Response in Type 1 Locus Idd 4 Molecular Genetic Analysis of the Spurrell (2006) (0)
Leukemic and Normal Stem Cell Transcriptional Signatures Determined by Functional Assays Are Predictive of the Overall Survival of AML Patients. (2009) (0)

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What Schools Are Affiliated With Jayne S. Danska?

Jayne S. Danska is affiliated with the following schools: