Jean Gruenberg | Academic Influence

Jean Gruenberg's AcademicInfluence.com Rankings

Jean Gruenberg

Biology

#7039

World Rank

#9887

Historical Rank

Biochemistry

#1445

World Rank

#1570

Historical Rank

biology Degrees

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Biology

Jean Gruenberg's Degrees

PhD Biochemistry University of Basel
Masters Chemistry University of Basel

Why Is Jean Gruenberg Influential?

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According to Wikipedia, Jean Gruenberg is a Swiss biologist, and a professor at the University of Geneva. His research in the fields of cell biology and biochemistry has significantly contributed to a better understanding of the molecular mechanisms involved in the intracellular traffic within eukaryotic cells, more especially in the endolysosomal pathway.

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Jean Gruenberg's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

rab5 controls early endosome fusion in vitro (1991) (1057)
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. (1994) (955)
A lipid associated with the antiphospholipid syndrome regulates endosome structure and function (1998) (782)
The endocytic pathway: a mosaic of domains (2001) (755)
The biogenesis of multivesicular endosomes (2004) (741)
Membrane transport in the endocytic pathway. (1995) (675)
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization (2004) (650)
Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport (1999) (640)
Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro (1989) (570)
Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest (2001) (544)
Vacuolar ATPase activity is required for endosomal carrier vesicle formation. (1994) (441)
Cytoplasmic dynein-dependent vesicular transport from early to late endosomes [published erratum appears in J Cell Biol 1994 Feb;124(3):397] (1993) (423)
Hypervariable C-termmal domain of rab proteins acts as a targeting signal (1991) (392)
An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes (1996) (372)
Endosome maturation, transport and functions. (2014) (369)
Separation and Characterization of Late Endosomal Membrane Domains* (2002) (358)
Late endosome motility depends on lipids via the small GTPase Rab7 (2002) (341)
Membrane traffic in endocytosis: insights from cell-free assays. (1989) (338)
Mechanisms of pathogen entry through the endosomal compartments (2006) (337)
The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components. (2000) (328)
Modulation of Rab5 and Rab7 Recruitment to Phagosomes by Phosphatidylinositol 3-Kinase (2003) (322)
Endosome-to-cytosol transport of viral nucleocapsids (2005) (320)
Nef-Induced CD4 Degradation A Diacidic-Based Motif in Nef Functions as a Lysosomal Targeting Signal through the Binding of β-COP in Endosomes (1999) (309)
Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells (1990) (296)
The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex. (2001) (281)
The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells. (2000) (279)
Annexin II is a major component of fusogenic endosomal vesicles (1993) (268)
Endocytosis in filter-grown Madin-Darby canine kidney cells (1989) (261)
Jamming the endosomal system: lipid rafts and lysosomal storage diseases. (2000) (253)
ALIX and the multivesicular endosome: ALIX in Wonderland. (2014) (244)
Specific release of membrane-bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol. (1997) (222)
Ion flux and the function of endosomes and lysosomes: pH is just the start (2011) (216)
Sonic Hedgehog Induces the Segregation of Patched and Smoothened in Endosomes (2002) (206)
Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells (2003) (205)
Intra-endosomal membrane traffic. (2006) (202)
Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels* (2008) (186)
Threonine Phosphorylation Diverts Internalized Epidermal Growth Factor Receptors from a Degradative Pathway to the Recycling Endosome* (2000) (184)
Functional Dissection of COP-I Subunits in the Biogenesis of Multivesicular Endosomes (1997) (173)
Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects. (2008) (171)
Core Protein Machinery for Mammalian Phosphatidylinositol 3,5-Bisphosphate Synthesis and Turnover That Regulates the Progression of Endosomal Transport (2007) (169)
The Steroidogenic Acute Regulatory Protein Homolog MLN64, a Late Endosomal Cholesterol-binding Protein* (2001) (168)
Late Endosomal Cholesterol Accumulation Leads to Impaired Intra-Endosomal Trafficking (2007) (158)
Single-cell analysis of population context advances RNAi screening at multiple levels (2012) (158)
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway (2003) (152)
Annexin A2-dependent polymerization of actin mediates endosome biogenesis. (2009) (149)
The arguments for pre-existing early and late endosomes. (1991) (148)
Involvement of the Transmembrane Protein p23 in Biosynthetic Protein Transport (1997) (147)
ALIX- and ESCRT-III–dependent sorting of tetraspanins to exosomes (2020) (145)
Inhibition of endocytic vesicle fusion in vitro by the cell-cycle control protein kinase cdc2 (1989) (144)
ARF1 Regulates pH-dependent COP Functions in the Early Endocytic Pathway* (2000) (143)
Lipids, lipid domains and lipid-protein interactions in endocytic membrane traffic. (1998) (129)
Lipid sorting and multivesicular endosome biogenesis. (2013) (128)
Intracellular Trafficking of Interleukin-1 Receptor I Requires Tollip (2006) (126)
Lipids in endocytic membrane transport and sorting. (2003) (126)
Endocytosis and signaling cascades: a close encounter (2001) (114)
Reconstitution of vesicle fusions occurring in endocytosis with a cell‐free system. (1986) (113)
Biogenesis of transport intermediates in the endocytic pathway (1999) (110)
The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi. (2008) (108)
The Secreted Form of Dengue Virus Nonstructural Protein NS1 Is Endocytosed by Hepatocytes and Accumulates in Late Endosomes: Implications for Viral Infectivity (2005) (105)
Molecular assemblies and membrane domains in multivesicular endosome dynamics. (2009) (101)
Two threshold values of low pH block endocytosis at different stages. (1987) (100)
Scanning electron microscope-analysis of the protrusions (knobs) present on the surface of Plasmodium falciparum-infected erythrocytes (1983) (99)
In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101. (2008) (97)
Acquisition of Hrs, an Essential Component of Phagosomal Maturation, Is Impaired by Mycobacteria (2004) (96)
Viral infection controlled by a calcium-dependent lipid-binding module in ALIX. (2013) (95)
Annexins in membrane traffic. (1993) (94)
Hrs and SNX3 Functions in Sorting and Membrane Invagination within Multivesicular Bodies (2008) (90)
Regulation of the EGF Transcriptional Response by Endocytic Sorting (2012) (86)
Annexin A2 Binding to Endosomes and Functions in Endosomal Transport Are Regulated by Tyrosine 23 Phosphorylation* (2009) (85)
Diversity of Raft-Like Domains in Late Endosomes (2007) (85)
Life in the lumen: The multivesicular endosome (2019) (84)
PNPLA3/adiponutrin functions in lipid droplet formation (2013) (82)
Coupled transport of p24 family members. (2000) (82)
Both Calmodulin and the Unconventional Myosin Myr4 Regulate Membrane Trafficking Along the Recycling Pathway of MDCK Cells (2000) (77)
The transmembrane protein p23 contributes to the organization of the Golgi apparatus. (2000) (72)
Localization of Lysobisphosphatidic Acid-Rich Membrane Domains in Late Endosomes (2001) (71)
Regulation of intracellular membrane transport. (1992) (67)
Interaction of anti-phospholipid antibodies with late endosomes of human endothelial cells. (2000) (65)
The p11/S100A10 Light Chain of Annexin A2 Is Dispensable for Annexin A2 Association to Endosomes and Functions in Endosomal Transport (2007) (61)
The ESCRT‐I Subunit TSG101 Controls Endosome‐to‐Cytosol Release of Viral RNA (2008) (61)
Selective Imaging of Late Endosomes with a pH-Sensitive Diazaoxatriangulene Fluorescent Probe. (2016) (59)
D-Glucose transport in Trypanosoma brucei. D-Glucose transport is the rate-limiting step of its metabolism. (1978) (57)
An internalized transmembrane protein resides in a fusion-competent endosome for less than 5 minutes. (1987) (56)
Plasticity of early endosomes. (1992) (52)
Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes (2011) (52)
ARF1 Regulates Nef-Induced CD4 Degradation (2004) (51)
L-leucyl-L-leucine methyl ester does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes (2017) (50)
Viruses and endosome membrane dynamics. (2009) (50)
Phosphorylation of GDI and membrane cycling of rab proteins (1993) (49)
NSF is required for transport from early to late endosomes. (1997) (48)
Endosomal Membrane Tension Regulates Escrt-III-Dependent Intra-Lumenal Vesicle Formation (2019) (48)
The structure of organelles of the endocytic pathway in hydrated cryosections of cultured cells. (1989) (46)
Dynamic rearrangements of erythrocyte membrane internal architecture induced by infection with Plasmodium falciparum. (1986) (45)
The trans-membrane protein p25 forms highly specialized domains that regulate membrane composition and dynamics (2003) (44)
Rapid access to synthetic lysobisphosphatidic acids using P(III) chemistry. (2000) (44)
Subcellular fractionation of tissue culture cells. (1989) (43)
Discovery of novel membrane binding structures and functions. (2014) (41)
The Tetraspanin CD 63 / lamp 3 Cycles between Endocytic and Secretory Compartments in Human Endothelial Cells (2000) (39)
Sliding doors: clathrin-coated pits or caveolae? (2003) (36)
Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting (2018) (36)
The N‐terminal domain of a rab protein is involved in membrane‐membrane recognition and/or fusion. (1994) (35)
Wnt directs the endosomal flux of LDL‐derived cholesterol and lipid droplet homeostasis (2015) (35)
Isolation and characterization of the plasma membrane of human erythrocytes infected with the malarial parasite Plasmodium falciparum. (1983) (34)
Regulation of the MVB Pathway by SCAMP3 (2012) (32)
Membrane transport in the endocytic pathway: Animal versus plant cells (2000) (32)
Immuno-isolation of vesicles using antigenic sites either located on the cytoplasmic or the exoplasmic domain of an implanted viral protein. A quantitative analysis. (1985) (31)
Inhibition of membrane fusion in vitro via cyclin B but not cyclin A. (1992) (31)
The Redox Sensor TXNL1 Plays a Regulatory Role in Fluid Phase Endocytosis (2007) (31)
Localization of β2-Glycoprotein 1 in Late Endosomes of Human Endothelial Cells (2001) (31)
Membrane Dynamics in Endocytosis: Structure–Function Relationship (2000) (30)
Immunoisolation using magnetic solid supports: subcellular fractionation for cell-free functional studies. (1989) (29)
Role of SNX16 in the Dynamics of Tubulo-Cisternal Membrane Domains of Late Endosomes (2011) (28)
TFAP2 transcription factors are regulators of lipid droplet biogenesis (2018) (27)
Oiling the wheels of the endocytic pathway. (2002) (27)
Supplementary Table 5 (2012) (26)
Moesin and cortactin control actin-dependent multivesicular endosome biogenesis (2016) (24)
Subcellular Fractionation of Tissue Culture Cells (2003) (24)
Evidence for Anticoagulant Activity and β2-GPI Accumulation in Late Endosomes of Endothelial Cells Induced by Anti-LBPA Antibodies (2002) (24)
SNX12 Role in Endosome Membrane Transport (2012) (24)
Interactions of rab5 with cytosolic proteins. (1992) (23)
Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells[S] (2019) (21)
Endosomal fractions from viral K‐ras‐transformed MDCK cells reveal transformation specific changes on two‐dimensional gel maps (1996) (21)
Studying lipids involved in the endosomal pathway. (2012) (21)
Membrane transport from early to late endosomes. (1995) (18)
The p24 family of transmembrane proteins at the interface between endoplasmic reticulum and Golgi apparatus (1999) (18)
Structure, dynamics, and energetics of lysobisphosphatidic acid (LBPA) isomers. (2010) (18)
Drug‐induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann–Pick type C cells and mice (2019) (17)
Capture of the small GTPase Rab5 by GDI: regulation by p38 MAP kinase. (2005) (16)
Concise synthesis of ether analogues of lysobisphosphatidic acid. (2005) (16)
Supplementary Table 6 (2012) (15)
Localization of beta2-glycoprotein 1 in late endosomes of human endothelial cells. (2001) (13)
Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice (2018) (12)
The Late Endosome (2016) (12)
Selective targeting of avidin/mannose 6-phosphate receptor chimeras to early or late endosomes. (2000) (12)
Immuno-isolation of subcellular components. (1988) (11)
Signaling from the far side. (2002) (11)
Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells (2018) (11)
Endosomal compartment of toad bladder epithelium. (1987) (11)
Coupled transport of p 24 family members (2000) (10)
Role of glycerol permeation in the bloodstream form of Trypanosoma brucei. (1980) (10)
Interaction of antiphospholipid antibodies with late endosomes of human endothelial cells. (1999) (10)
Nanoparticle entry into cells; the cell biology weak link. (2022) (9)
Fusion in the endocytic pathway reconstituted in a cell-free system using immuno-isolated fractions. (1988) (8)
Interactions of liposomes with Trypanosoma brucei plasma membrane. (1979) (8)
Automated Microscopy and High Content Screens (Phenotypic Screens) in Academia Labs. (2016) (7)
Supplementary Table 8 (2014) (7)
Isoproterenol-induced redistribution of endosomes in cardiac myocytes. (1994) (7)
Subcellular Fractionation of Tissue Culture Cells (2003) (5)
Membranes and sorting. (1995) (5)
The topology of the lymphotoxin β receptor that accumulates upon endolysosomal dysfunction dictates the NF-κB signaling outcome (2018) (5)
Secondary structure and 1H, 13C, 15N resonance assignments of the endosomal sorting protein sorting nexin 3 (2015) (4)
Toxoplasma: Guess Who's Coming to Dinner (2006) (4)
Endosomal Membrane Dynamics (2007) (3)
Duelling functions of the V‐ATPase (2011) (3)
Lipid Membrane Domains in Endosomes (2006) (3)
3-Kinase to Phagosomes by Phosphatidylinositol Modulation of Rab 5 and Rab 7 Recruitment (2003) (3)
In Vitro Polymerization of F-actin on Early Endosomes. (2017) (3)
Flipper Probes for the Community. (2021) (2)
Immunoisolation of Organelles Using Magnetic Solid Supports (2006) (2)
Generation of proteoliposomes from subcellular fractions (1997) (2)
An MBoC Favorite: Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology (2012) (2)
Caenorhabditis elegans Neuronal Calcium Sensor-1: From Gene To Behavior (1997) (1)
Close encounter of the third kind: the ER meets endosomes at fission sites. (2014) (1)
Regulation of Endocytic Membrane Traffic (1992) (1)
Erratum: Inhibition of membrane fusion in vitro via cyclin B but not cyclin A (Journal of Biological Chemistry (1992) 267 (6183-6187)) (1992) (1)
In vitro studies of endocytic membrane traffic (2005) (1)
A novel strategy to identify drugs that interfere with endosomal lipids. (2011) (1)
TFAP 2 transcription factors are 1 regulators of lipid droplet biogenesis 2 3 4 (0)
Assays Measuring Membrane Transport in the Endocytic Pathway (2006) (0)
Scanning Electron Microscope-Analysis of the Protrusions (Knobs) Present on the Surface (2003) (0)
Secondary structure and 1H, 13C, 15N resonance assignments of the endosomal sorting protein sorting nexin 3 (2015) (0)
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization. (2009) (0)
Table of Contents (1994) (0)
Regulation of Early Endosome Fusion In Vitro (1993) (0)
Table of Contents (1986) (0)
Mechanisms regulating membrane traffic in the endocytic pathway (1998) (0)
Liposome-trypanosome interactions. (1980) (0)
THE POLARIZED ORGANIZATION OF THE ENDOCYTIC PATHWAYS IN MDCK EPITHELIAL-CELLS (1991) (0)
Localization of rab Proteins (1991) (0)
Solution structure of the full length sorting nexin 3 (2016) (0)
Interactions of rab 5 with Cytosolic Proteins * (2001) (0)
[The biogenesis of intra-lumenal vesicles is regulated by endosomal membrane tension]. (2021) (0)
THE PATHWAY OF VSV ENTRY INTO CELLS (2015) (0)
[Endocytosis: the Trojan Horse of viral infection]. (2005) (0)
Model system for cell fractionation using an immuno adsorption method (1983) (0)
Endosomal lipids in trafficking and signaling (2018) (0)
9 Membrane Traffic in the Endocytic Pathway of Eukaryotic Cells (2004) (0)
Functional and biochemical characterization of pH-dependent COP-I binding to early endosomal membranes (1998) (0)
L’endocytose, cheval de Troie pour l’infection virale (2005) (0)
Author response for "Life in the lumen: the multivesicular endosome" (2019) (0)
[Cell biology of lysobisphosphatidic acid]. (1999) (0)
Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting (2018) (0)

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