Jean-Louis Vincent
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Philosophy
Jean-Louis Vincent's Degrees
- Doctorate Medicine Université libre de Bruxelles
- PhD Medical Sciences Université libre de Bruxelles
Why Is Jean-Louis Vincent Influential?
(Suggest an Edit or Addition)According to Wikipedia, Baron Jean-Louis Vincent is a Belgian physician and Professor of intensive care medicine at the Université libre de Bruxelles and intensivist in the Department of Intensive Care at Erasme University Hospital in Brussels.
Jean-Louis Vincent's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). (2016) (13437)
- The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure (1996) (8425)
- Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012 (2013) (5832)
- Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012 (2013) (5425)
- 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference (2003) (4955)
- 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference (2003) (4227)
- Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 (2007) (4099)
- Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 (2008) (3717)
- Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 (2017) (3647)
- Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2016 (2017) (2976)
- Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. (1998) (2961)
- Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock (2004) (2604)
- The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. (1995) (2604)
- Sepsis in European intensive care units: Results of the SOAP study* (2006) (2561)
- International study of the prevalence and outcomes of infection in intensive care units. (2009) (2327)
- Serial evaluation of the SOFA score to predict outcome in critically ill patients. (2001) (2235)
- Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock (2004) (1702)
- Anemia and blood transfusion in critically ill patients. (2002) (1587)
- Comparison of dopamine and norepinephrine in the treatment of shock. (2010) (1451)
- Microvascular blood flow is altered in patients with sepsis. (2002) (1321)
- Sepsis biomarkers: a review (2010) (1186)
- Efficacy and safety of recombinant human activated protein C for severe sepsis. (2001) (1153)
- Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine (2014) (1127)
- The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material (2012) (1106)
- Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock* (2004) (1078)
- Mortality after surgery in Europe: a 7 day cohort study (2012) (1055)
- The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition (2016) (984)
- Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury (2013) (977)
- Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. (1993) (935)
- Recombinant Human Interleukin 1 Receptor Antagonist in the Treatment of Patients With Sepsis Syndrome: Results From a Randomized, Double-blind, Placebo-Controlled Trial (1994) (889)
- Management of bleeding and coagulopathy following major trauma: an updated European guideline (2013) (885)
- Circulatory shock. (2013) (859)
- Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. (1997) (841)
- Yearbook of Intensive Care and Emergency Medicine (1995) (841)
- A positive fluid balance is associated with a worse outcome in patients with acute renal failure (2008) (827)
- The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study (1999) (826)
- Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit. (2014) (822)
- Sepsis: a roadmap for future research. (2015) (775)
- Transfusion requirements after cardiac surgery: the TRACS randomized controlled trial. (2010) (757)
- Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score (2000) (748)
- Management of bleeding following major trauma: an updated European guideline (2010) (731)
- The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition (2019) (716)
- Serial blood lactate levels can predict the development of multiple organ failure following septic shock. (1996) (712)
- Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. (2013) (656)
- Physiotherapy for adult patients with critical illness: recommendations of the European Respiratory Society and European Society of Intensive Care Medicine Task Force on Physiotherapy for Critically Ill Patients (2008) (649)
- Pulse pressure variations to predict fluid responsiveness: influence of tidal volume (2005) (640)
- Has the mortality of septic shock changed with time. (1998) (615)
- Sepsis and septic shock (2016) (595)
- Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock. (1991) (584)
- Sepsis definitions: time for change (2013) (572)
- Hypoalbuminemia in Acute Illness: Is There a Rationale for Intervention?: A Meta-Analysis of Cohort Studies and Controlled Trials (2003) (549)
- Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update (2004) (520)
- Clinical review: Scoring systems in the critically ill (2010) (512)
- Serial lactate determinations during circulatory shock (1983) (490)
- Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study. (2012) (463)
- The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects* (2006) (449)
- Procalcitonin used as a marker of infection in the intensive care unit. (1999) (443)
- Microcirculatory Alterations in Patients With Severe Sepsis: Impact of Time of Assessment and Relationship With Outcome* (2013) (440)
- Management of bleeding following major trauma: a European guideline (2007) (438)
- Influence of an anti‐tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis (1993) (428)
- Severe sepsis in cirrhosis (2009) (419)
- Forgoing life support in western European intensive care units: the results of an ethical questionnaire. (1999) (417)
- Mortality rates for patients with acute lung injury/ARDS have decreased over time. (2008) (416)
- C-reactive protein levels correlate with mortality and organ failure in critically ill patients. (2003) (414)
- Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study (2020) (413)
- Microvascular alterations in patients with acute severe heart failure and cardiogenic shock. (2004) (411)
- Intra-Arrest Transnasal Evaporative Cooling: A Randomized, Prehospital, Multicenter Study (PRINCE Pre-ROSC IntraNasal Cooling Effectiveness) (2010) (406)
- Dear SIRS, I'm sorry to say that I don't like you... (1997) (403)
- High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. (2005) (400)
- Control of Confounding and Reporting of Results in Causal Inference Studies. Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals (2019) (390)
- A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis* (2010) (384)
- Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: Time for a reevaluation (2000) (381)
- Has mortality from acute renal failure decreased? A systematic review of the literature. (2005) (377)
- Fluid challenge revisited (2006) (375)
- Characteristics and outcomes of cancer patients in European ICUs (2009) (372)
- Time course of platelet counts in critically ill patients (2002) (366)
- Does dopamine administration in shock influence outcome? Results of the Sepsis Occurrence in Acutely Ill Patients (SOAP) Study* (2006) (364)
- Early changes in organ function predict eventual survival in severe sepsis* (2005) (358)
- Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage. (2010) (341)
- Clinical review: Update on hemodynamic monitoring - a consensus of 16 (2011) (340)
- Monitoring the microcirculation in the critically ill patient: current methods and future approaches (2010) (339)
- A positive fluid balance is an independent prognostic factor in patients with sepsis (2015) (337)
- Update in Intensive Care and Emergency Medicine (1989) (334)
- Effects of dopamine, norepinephrine, and epinephrine on the splanchnic circulation in septic shock: which is best? (2003) (329)
- Practice parameters for hemodynamic support of sepsis in adult patients in sepsis. Task Force of the American College of Critical Care Medicine, Society of Critical Care Medicine. (1999) (328)
- The prognostic value of muscle StO2 in septic patients (2007) (326)
- Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: Further evidence for survival and safety and implications for early treatment* (2005) (323)
- Nosocomial infections in adult intensive-care units (2003) (321)
- Metabolic and nutritional support of critically ill patients: consensus and controversies (2015) (318)
- Effects of nitric oxide in septic shock. (2000) (313)
- The value of blood lactate kinetics in critically ill patients: a systematic review (2016) (309)
- Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study. (2004) (308)
- Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock (2010) (305)
- Neutrophil elastase inhibition in acute lung injury: Results of the STRIVE study (2004) (303)
- Mechanisms and treatment of organ failure in sepsis (2018) (301)
- Dopamine versus norepinephrine in the treatment of septic shock: A meta-analysis* (2012) (300)
- Combined measurements of blood lactate concentrations and gastric intramucosal pH in patients with severe sepsis. (1995) (297)
- Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial* (2003) (292)
- Variation in Use of Blood Transfusion in Coronary Artery Bypass Graft Surgery (2010) (292)
- What is an intensive care unit? A report of the task force of the World Federation of Societies of Intensive and Critical Care Medicine (2017) (290)
- APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases (2017) (290)
- Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock (2013) (286)
- A PILOT-CONTROLLED STUDY OF A POLYMYXIN B-IMMOBILIZED HEMOPERFUSION CARTRIDGE IN PATIENTS WITH SEVERE SEPSIS SECONDARY TO INTRA-ABDOMINAL INFECTION (2005) (285)
- Sedative and analgesic practice in the intensive care unit: the results of a European survey. (2001) (284)
- Diabetic status and the relation of the three domains of glycemic control to mortality in critically ill patients: an international multicenter cohort study (2013) (278)
- Comfort and patient-centred care without excessive sedation: the eCASH concept (2016) (278)
- Correlation of serial blood lactate levels to organ failure and mortality after trauma. (1995) (277)
- Candida bloodstream infections in intensive care units: Analysis of the extended prevalence of infection in intensive care unit study* (2011) (276)
- Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis (2003) (276)
- Myocardium is a major source of proinflammatory cytokines in patients undergoing cardiopulmonary bypass. (1996) (270)
- Albumin administration improves organ function in critically ill hypoalbuminemic patients: A prospective, randomized, controlled, pilot study* (2006) (267)
- Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017. (2020) (263)
- Measures, markers, and mediators: Toward a staging system for clinical sepsis. A Report of the Fifth Toronto Sepsis Roundtable, Toronto, Ontario, Canada, October 25–26, 2000 (2003) (263)
- Cytokine responses to cardiopulmonary bypass: lessons learned from cardiac transplantation. (1997) (263)
- Effects of fluids on microvascular perfusion in patients with severe sepsis (2010) (263)
- Vasopressor and inotropic support in septic shock: An evidence-based review (2004) (257)
- The Multiple Organ Dysfunction Score (MODS) versus the Sequential Organ Failure Assessment (SOFA) score in outcome prediction (2002) (254)
- Body temperature alterations in the critically ill (2004) (251)
- Ethics and end-of-life care for adults in the intensive care unit (2010) (247)
- A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients With Sepsis and Suspected Disseminated Intravascular Coagulation* (2013) (244)
- Recommendations on the use of recombinant activated factor VII as an adjunctive treatment for massive bleeding – a European perspective (2006) (243)
- Microvascular response to red blood cell transfusion in patients with severe sepsis* (2007) (242)
- Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care Medicine (2018) (242)
- Give your patient a fast hug (at least) once a day* (2005) (241)
- Platelet function in sepsis (2002) (237)
- Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: The RAMSES Study (2001) (236)
- Clinical trials of immunomodulatory therapies in severe sepsis and septic shock. (2002) (234)
- Management of the critically ill patient with cirrhosis: A multidisciplinary perspective. (2016) (231)
- COST-EFFECTIVENESS OF DROTRECOGIN ALFA (ACTIVATED) IN THE TREATMENT OF SEVERE SEPSIS (2002) (227)
- High-protein enteral nutrition enriched with immune-modulating nutrients vs standard high-protein enteral nutrition and nosocomial infections in the ICU: a randomized clinical trial. (2014) (226)
- Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit (2018) (220)
- Administration of anti-TNF antibody improves left ventricular function in septic shock patients. Results of a pilot study. (1992) (220)
- Oxygen uptake/supply dependency. Effects of short-term dobutamine infusion. (1990) (219)
- Antibiotic strategies in the era of multidrug resistance (2016) (215)
- Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis (2019) (215)
- Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients (2020) (215)
- Understanding pathways to death in patients with COVID-19 (2020) (211)
- International differences in end-of-life attitudes in the intensive care unit: results of a survey. (2005) (208)
- The Surviving Sepsis Campaign: raising awareness to reduce mortality (2003) (208)
- An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence in Acutely ill Patients (SOAP) study (2006) (205)
- Less invasive hemodynamic monitoring in critically ill patients (2016) (203)
- Veno-arterial carbon dioxide gradient in human septic shock. (1992) (201)
- Evaluation of sublingual and gut mucosal microcirculation in sepsis: A quantitative analysis* (2009) (199)
- An open-label dose escalation study of the nitric oxide synthase inhibitor, NG-methyl-L-arginine hydrochloride (546C88), in patients with septic shock (1999) (197)
- Sublingual capnometry tracks microcirculatory changes in septic patients (2006) (197)
- The effects of etomidate on adrenal responsiveness and mortality in patients with septic shock (2009) (197)
- Higher Fluid Balance Increases the Risk of Death From Sepsis: Results From a Large International Audit* (2017) (197)
- Are Blood Transfusions Associated with Greater Mortality Rates?: Results of the Sepsis Occurrence in Acutely Ill Patients Study (2008) (197)
- Vancomycin Dosing in Critically Ill Patients: Robust Methods for Improved Continuous-Infusion Regimens (2011) (195)
- Microcirculatory alterations: potential mechanisms and implications for therapy (2011) (192)
- Association between duration of storage of transfused red blood cells and morbidity and mortality in adult patients: myth or reality? (2009) (191)
- Multicenter, double-blind, placebo-controlled study of the use of filgrastim in patients hospitalized with pneumonia and severe sepsis* (2003) (191)
- Reducing mortality in sepsis: new directions (2002) (190)
- The epidemiology of acute respiratory failure in critically ill patients(*). (2002) (187)
- Recommended β-lactam regimens are inadequate in septic patients treated with continuous renal replacement therapy (2011) (186)
- Red blood cell rheology in sepsis (2003) (186)
- Application of SOFA score to trauma patients (1999) (186)
- Vasopressin versus Norepinephrine in Patients with Vasoplegic Shock after Cardiac Surgery: The VANCS Randomized Controlled Trial (2017) (185)
- Human cytokine responses to cardiac transplantation and coronary artery bypass grafting. (1996) (184)
- Influence of Respiratory Rate on Stroke Volume Variation in Mechanically Ventilated Patients (2009) (181)
- Erythropoietin response is blunted in critically ill patients (1997) (181)
- Measurements of right ventricular volumes during fluid challenge. (1990) (181)
- Let us use the pulmonary artery catheter correctly and only when we need it (2005) (180)
- Renal replacement therapy in acute kidney injury: controversy and consensus (2015) (180)
- Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial. (2019) (177)
- The last 100 years of sepsis. (2006) (177)
- Microvascular dysfunction as a cause of organ dysfunction in severe sepsis (2005) (176)
- How can the response to volume expansion in patients with spontaneous respiratory movements be predicted? (2006) (176)
- Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock (2010) (175)
- We should abandon randomized controlled trials in the intensive care unit (2010) (174)
- Biomarkers of sepsis: time for a reappraisal (2020) (173)
- Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial (2012) (173)
- Time course of hemoglobin concentrations in nonbleeding intensive care unit patients (2003) (172)
- Coagulation in sepsis (2004) (171)
- A profile of European intensive care unit physiotherapists (2000) (170)
- Increased mortality associated with methicillin-resistant Staphylococcus aureus (MRSA) infection in the intensive care unit: results from the EPIC II study. (2011) (170)
- The Clinical Challenge of Sepsis Identification and Monitoring (2016) (169)
- Transfusion Requirements in Surgical Oncology Patients: A Prospective, Randomized Controlled Trial (2015) (169)
- Fluid resuscitation in severe sepsis and septic shock: An evidence-based review (2004) (168)
- Lactate production by the lungs in acute lung injury. (1997) (168)
- The Next Generation of Sepsis Clinical Trial Designs: What Is Next After the Demise of Recombinant Human Activated Protein C?* (2014) (168)
- Development of ionized hypomagnesemia is associated with higher mortality rates (2003) (165)
- Scoring systems for assessing organ dysfunction and survival. (2000) (164)
- Effects of changes in arterial pressure on organ perfusion during septic shock (2011) (164)
- Multicenter, randomized, controlled trials evaluating mortality in intensive care: Doomed to fail? (2008) (163)
- Dobutamine administration in septic shock: addition to a standard protocol. (1990) (162)
- Effects of drotrecogin alfa activated on microcirculatory alterations in patients with severe sepsis (2006) (162)
- Perioperative cardiovascular monitoring of high-risk patients: a consensus of 12 (2015) (162)
- Obesity is associated with increased morbidity but not mortality in critically ill patients (2008) (162)
- Promoting Global Research Excellence in Severe Sepsis (PROGRESS): Lessons from an International Sepsis Registry (2009) (160)
- Molecular Characterization of an Epidemic Clone of Panantibiotic-Resistant Pseudomonas aeruginosa (2005) (158)
- Global Prospective Epidemiologic and Surveillance Study of Ventilator-Associated Pneumonia due to Pseudomonas aeruginosa* (2014) (158)
- Albumin administration in the acutely ill: what is new and where next? (2014) (157)
- Cerebral microcirculation is impaired during sepsis: an experimental study (2010) (154)
- Rapid Diagnosis of Infection in the Critically Ill, a Multicenter Study of Molecular Detection in Bloodstream Infections, Pneumonia, and Sterile Site Infections* (2015) (154)
- Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial (2003) (152)
- Timing of tracheotomy in ICU patients: a systematic review of randomized controlled trials (2015) (152)
- The Impact of Hospital and ICU Organizational Factors on Outcome in Critically Ill Patients: Results From the Extended Prevalence of Infection in Intensive Care Study* (2015) (149)
- Outcome measures for clinical research in sepsis: A report of the 2nd Cambridge Colloquium of the International Sepsis Forum (2005) (147)
- qSOFA does not replace SIRS in the definition of sepsis (2016) (147)
- Epidemiology, diagnosis and treatment of systemic Candida infection in surgical patients under intensive care (1998) (146)
- Can changes in arterial pressure be used to detect changes in cardiac index during fluid challenge in patients with septic shock? (2012) (145)
- Morbidity in hospitalized patients receiving human albumin: A meta-analysis of randomized, controlled trials* (2004) (145)
- Implementation of the Surviving Sepsis Campaign guidelines for severe sepsis and septic shock: we could go faster. (2008) (144)
- Increased incidence of co-infection in critically ill patients with influenza (2016) (144)
- Microcirculatory alterations in cardiac surgery: effects of cardiopulmonary bypass and anesthesia. (2009) (144)
- Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference (2017) (141)
- The cuff leak test to predict failure of tracheal extubation for laryngeal edema (2002) (140)
- Does N-acetyl-L-cysteine influence cytokine response during early human septic shock? (1998) (140)
- Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals (2020) (139)
- Methylene blue administration in septic shock: A clinical trial (1995) (139)
- Evidence-based colloid use in the critically ill: American Thoracic Society Consensus Statement. (2004) (139)
- suPAR as a prognostic biomarker in sepsis (2012) (138)
- Epidemiology and outcome of acute respiratory failure in intensive care unit patients (2003) (138)
- High lactate levels are predictors of major complications after cardiac surgery. (2013) (137)
- Understanding cardiac output (2008) (137)
- Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 (2008) (135)
- Arteriovenous differences in PCO2 and pH are good indicators of critical hypoperfusion. (1993) (134)
- Methylene blue administration in septic shock: a clinical trial. (1995) (134)
- The ICM research agenda on intensive care unit-acquired weakness (2017) (131)
- Abandon the Mouse Research Ship? Not Just Yet! (2014) (131)
- REDUCTION OF STRESS/ CATECHOLAMINE-INDUCED CARDIAC NECROSIS BY BETA1-SELECTIVE BLOCKADE (1987) (131)
- Serum levels of C-reactive protein and procalcitonin in critically ill patients with cirrhosis of the liver. (2005) (130)
- The pulmonary artery catheter: In medio virtus (2008) (129)
- Monitoring Gastric Mucosal Carbon Dioxide Pressure Using Gas Tonometry: In Vitro and in Vivo Validation Studies (1997) (129)
- Estimating left ventricular filling pressure during positive end-expiratory pressure in humans. (1991) (129)
- Arterial pressure-based cardiac output monitoring: a multicenter validation of the third-generation software in septic patients (2010) (128)
- Optimizing mean arterial pressure in septic shock: a critical reappraisal of the literature (2015) (127)
- Drowning: a review of epidemiology, pathophysiology, treatment and prevention. (2004) (127)
- Ten reasons why we should NOT use severity scores as entry criteria for clinical trials or in our treatment decisions* (2010) (126)
- SOFA and mortality endpoints in randomized controlled trials: a systematic review and meta-regression analysis (2017) (126)
- Management of nutrition in European intensive care units: results of a questionnaire (1999) (124)
- Platelet function in sepsis (2004) (124)
- Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) (2016) (123)
- Near-infrared spectroscopy technique to evaluate the effects of red blood cell transfusion on tissue oxygenation (2009) (123)
- Nomenclature for renal replacement therapy in acute kidney injury: basic principles (2016) (122)
- Critical care - where have we been and where are we going? (2013) (122)
- Clinical review: Respiratory monitoring in the ICU - a consensus of 16 (2012) (121)
- Myocardial depression characterizes the fatal course of septic shock. (1992) (121)
- Diabetes does not alter mortality or hemostatic and inflammatory responses in patients with severe sepsis* (2010) (121)
- Blood interleukin 10 levels parallel the severity of septic shock. (1997) (121)
- Cultural differences in end-of-life care (2001) (120)
- Neuroprotection in acute brain injury: an up-to-date review (2015) (118)
- Does hepato-splanchnic VO2/DO2 dependency exist in critically ill septic patients? (1998) (117)
- Relevance of albumin in modern critical care medicine. (2009) (117)
- Nivolumab plus interferon-γ in the treatment of intractable mucormycosis. (2017) (117)
- Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis (2003) (117)
- Information in the ICU: are we being honest with our patients? The results of a European questionnaire (1998) (117)
- European attitudes towards ethical problems in intensive care medicine: Results of an ethical questionnaire (2005) (116)
- How to assess prognosis after cardiac arrest and therapeutic hypothermia (2014) (116)
- Hemodynamic support in septic shock (2001) (115)
- Renal perfusion in sepsis: from macro- to microcirculation. (2017) (115)
- Patterns and early evolution of organ failure in the intensive care unit and their relation to outcome (2012) (115)
- Relationship between red cell storage duration and outcomes in adults receiving red cell transfusions: a systematic review (2013) (115)
- Round table conference on clinical trials for the treatment of sepsis. (1995) (115)
- Alterations of red blood cell shape and sialic acid membrane content in septic patients (2003) (115)
- Comparison of cellulose diacetate and polysulfone membranes in the outcome of acute renal failure. A prospective randomized study. (2000) (115)
- Should we measure the central venous pressure to guide fluid management? Ten answers to 10 questions (2018) (115)
- Role of albumin in diseases associated with severe systemic inflammation: Pathophysiologic and clinical evidence in sepsis and in decompensated cirrhosis. (2016) (114)
- Relative adrenal insufficiency in patients with septic shock: Comparison of low-dose and conventional corticotropin tests* (2005) (114)
- Effect of positive end-expiratory pressure on right ventricular function in humans. (1992) (114)
- Invasive aspergillosis in patients with severe alcoholic hepatitis. (2014) (114)
- Surviving sepsis campaign guidelines (2006) (112)
- Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study (2011) (111)
- Oxygen free radicals in ARDS, septic shock and organ dysfunction (2000) (110)
- Protective effects of N-acetyl-L-cysteine in endotoxemia. (1994) (110)
- Extracranial complications in patients with acute brain injury: a post-hoc analysis of the SOAP study (2008) (109)
- Brain function in the vegetative state. (2002) (109)
- Is albumin administration in the acutely ill associated with increased mortality? Results of the SOAP study (2005) (109)
- Is worsening multiple organ failure the cause of death in patients with severe sepsis?* (2011) (108)
- Recovery after critical illness: putting the puzzle together—a consensus of 29 (2017) (108)
- Right ventricular dysfunction in septic shock: assessment by measurements of right ventricular ejection fraction using the thermodilution technique (1989) (107)
- Oxygen transport—the oxygen delivery controversy (2004) (107)
- Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base (2020) (106)
- Crystalloids Versus Colloids: Exploring Differences in Fluid Requirements by Systematic Review and Meta-Regression (2015) (106)
- Transfusion in the intensive care unit (2006) (106)
- Interleukin-6 administration has no acute hemodynamic or hematologic effect in the dog. (1991) (106)
- Application of SOFA score to trauma patients. Sequential Organ Failure Assessment. (1999) (106)
- Ventriculostomy-related infections in critically ill patients: a 6-year experience. (2005) (105)
- Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP) (2018) (104)
- Being Overweight Is Associated With Greater Survival in ICU Patients: Results From the Intensive Care Over Nations Audit* (2015) (104)
- Effects of hydroxyethyl starch administration on renal function in critically ill patients. (2005) (104)
- What type of monitoring has been shownto improve outcomes in acutely ill patients? (2008) (104)
- 36th International Symposium on Intensive Care and Emergency Medicine (2016) (103)
- 36th International Symposium on Intensive Care and Emergency Medicine (2016) (103)
- Elevated β-lactam concentrations associated with neurological deterioration in ICU septic patients. (2015) (102)
- Acute kidney injury after cardiac arrest (2013) (101)
- Antibiotic strategies in severe nosocomial sepsis: Why do we not de-escalate more often?* (2012) (101)
- Predictive value of microalbuminuria in medical ICU patients: results of a pilot study. (2001) (100)
- Low-dose vasopressin in the treatment of septic shock in sheep. (2003) (99)
- Early alterations of red blood cell rheology in critically ill patients* (2009) (98)
- Does a Higher Positive End Expiratory Pressure Decrease Mortality in Acute Respiratory Distress Syndrome?: A Systematic Review and Meta-analysis (2009) (98)
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- Continuous epileptiform discharges in patients treated with cefepime or meropenem. (2011) (38)
- The intensive care medicine research agenda for airways, invasive and noninvasive mechanical ventilation (2017) (38)
- Challenges in the management of septic shock: a narrative review (2019) (38)
- EARLY- VERSUS LATE-ONSET SHOCK IN EUROPEAN INTENSIVE CARE UNITS (2007) (38)
- Correction of hypocalcaemia in the critically ill: What is the haemodynamic benefit? (1995) (37)
- Cardiovascular effects of moderate normovolaemic haemodilution during enflurane–nitrous oxide anaesthesia in man (1994) (37)
- Administration of enoximone in cardiogenic shock. (1988) (37)
- Fluid resuscitation with hypertonic saline in endotoxic shock. (1986) (37)
- Post mortem examination in the intensive care unit: still useful? (2004) (37)
- Prevention of nosocomial bacterial pneumonia (1999) (37)
- Effects on right ventricular function of a change from dopamine to dobutamine in critically ill patients. (1988) (37)
- Tissue capnometry: does the answer lie under the tongue? (2004) (36)
- Urea for treatment of acute SIADH in patients with subarachnoid hemorrhage: a single-center experience (2012) (36)
- Metabolic support in sepsis and multiple organ failure: More questions than answers … (2007) (36)
- Effects of fluid challenge on gastric mucosal PCO2 in septic patients (2004) (36)
- Cardiovascular and microvascular responses to mild hypothermia in an ovine model. (2012) (36)
- Poor adherence to guidelines for preventing central line-associated bloodstream infections (CLABSI): results of a worldwide survey (2016) (36)
- Timing of cardiac output measurements during mechanical ventilation. (1986) (36)
- PROGNOSTIC VALUE OF ADMISSION SERUM LACTATE CONCENTRATIONS IN INTENSIVE CARE UNIT PATIENTS (2010) (36)
- Beneficial effects of recombinant human activated protein C in a ewe model of septic shock* (2007) (36)
- Systematic assessment of fluid responsiveness during early septic shock resuscitation: secondary analysis of the ANDROMEDA-SHOCK trial (2020) (35)
- Intravenous nicardipine in the treatment of postoperative arterial hypertension. (1997) (35)
- Near-Continuous Glucose Monitoring Makes Glycemic Control Safer in ICU Patients* (2018) (35)
- Strongyloides disseminated infection successfully treated with parenteral ivermectin: case report with drug concentration measurements and review of the literature. (2013) (35)
- Preoperative abnormalities in serum sodium concentrations are associated with higher in-hospital mortality in patients undergoing major surgery. (2016) (35)
- Annual Update in Intensive Care and Emergency Medicine 2018 (2018) (35)
- Effects of fluid administration on renal perfusion in critically ill patients (2015) (35)
- Septic shock without documented infection: an uncommon entity with a high mortality (1999) (35)
- Tirilazad mesylate (U-74006F) inhibits effects of endotoxin in dogs. (1995) (35)
- Prone positioning in acute respiratory failure: survey of Belgian ICU nurses (2002) (35)
- "Let's give some fluid and see what happens" versus the "mini-fluid challenge". (2011) (35)
- How to use an article on therapy or prevention: pneumonia prevention using subglottic secretion drainage. (1997) (35)
- Roundtable Conference on Clinical Trials for the Treatment of Sepsis. Brussels, March 12-14, 1994. (1995) (34)
- Intensive care and emergency medicine: progress over the past 25 years. (2006) (34)
- Serum S100B Protein Could Help to Detect Cerebral Complications Associated with Extracorporeal Membrane Oxygenation (ECMO) (2014) (34)
- Hydrochloric acid infusion for treatment of metabolic alkalosis associated with respiratory acidosis. (1989) (34)
- French Intensive Care Society, International congress – Réanimation 2016 (2016) (33)
- Guidelines for the utilisation of intensive care units (1994) (33)
- Correction of metabolic acidosis in experimental CPR: a comparative study of sodium bicarbonate, carbicarb, and dextrose. (1991) (33)
- Prognostic implications of blood lactate concentrations after cardiac arrest: a retrospective study (2017) (33)
- Effects of propofol, etomidate, and pentobarbital on critical oxygen delivery (2000) (33)
- Acute Barium Intoxication and Hemodiafiltration (2003) (33)
- A double-blind placebo-controlled study to evaluate the safety and efficacy of L-2-oxothiazolidine-4-carboxylic acid in the treatment of patients with acute respiratory distress syndrome* (2008) (33)
- Monocyte CD40 Expression in Severe Sepsis (2003) (33)
- Cortisol Is an Associated-Risk Factor of Brain Dysfunction in Patients with Severe Sepsis and Septic Shock (2014) (33)
- cardiopulmonary bypass in patients (2003) (33)
- Selective digestive decontamination: for everyone, everywhere? (2003) (33)
- Microbial resistance: lessons from the EPIC study. European Prevalence of Infection. (2000) (33)
- Dynamic microsimulation to model multiple outcomes in cohorts of critically ill patients (2004) (33)
- Evaluation of a new, rapid lactate analyzer in critical care (1999) (32)
- Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression (2006) (32)
- The Reproducibility of Stewart Parameters for Acid-Base Diagnosis Using Two Central Laboratory Analyzers (2009) (32)
- Assessment of cardiac index in anemic patients. (2000) (32)
- Critically Ill Elderly Adults with Infection: Analysis of the Extended Prevalence of Infection in Intensive Care Study (2013) (32)
- Personalized Versus Protocolized Fluid Management Using Noninvasive Hemodynamic Monitoring (Clearsight System) in Patients Undergoing Moderate-Risk Abdominal Surgery. (2019) (32)
- Task Force: Guidelines for the problem of sepsis (ESICM) (1994) (32)
- Oxygen transport : principles and practice (1993) (32)
- Evaluation of cardiac output in intensive care using a non‐invasive arterial pulse contour technique (Nexfin®) compared with echocardiography (2013) (32)
- Calcium chloride in experimental electromechanical dissociation: A placebo‐controlled trial in dogs (1987) (32)
- Comparison of continuous thermodilution and bolus cardiac output measurements in septic shock (2002) (32)
- Anemia in the intensive care unit. (2003) (32)
- Infection in Intensive Care Units International Study of the Prevalence and Outcomes of (2009) (32)
- Combination of veno-arterial extracorporeal membrane oxygenation and hypothermia for out-of-hospital cardiac arrest due to Taxus intoxication. (2014) (31)
- Corticosteroids in severe COVID-19: a critical view of the evidence (2020) (31)
- Critical care--an all-encompassing specialty. (2013) (31)
- Determination of oxygen delivery and consumption versus cardiac index and oxygen extraction ratio. (1996) (31)
- Tissue Oxygen Utilization (1991) (31)
- Critical care evidence--new directions. (2015) (31)
- Predictors of major complications after elective abdominal surgery in cancer patients (2018) (31)
- USE OF LOW TIDAL VOLUME IN SEPTIC SHOCK MAY DECREASE SEVERITY OF SUBSEQUENT ACUTE LUNG INJURY (2004) (31)
- Septic shock: Particular type of acute circulatory failure (1990) (30)
- Sepsis biomarkers. Value and limitations. (2014) (30)
- Vaccine development and passive immunization for Pseudomonas aeruginosa in critically ill patients: a clinical update. (2014) (30)
- Endocan as an early biomarker of severity in patients with acute respiratory distress syndrome (2017) (30)
- Talactoferrin in Severe Sepsis: Results From the Phase II/III Oral tAlactoferrin in Severe sepsIS Trial (2015) (30)
- Effects of &agr; - and &bgr; -adrenergic stimulation on hepatosplanchnic perfusion and oxygen extraction in endotoxic shock (2001) (30)
- Relationship between CRP and hypofibrinolysis: Is this a possible mechanism to explain the association between CRP and outcome in critically ill patients? (2004) (30)
- Renin as a Marker of Tissue-Perfusion and Prognosis in Critically Ill Patients* (2019) (30)
- COMPARISON OF HYPERTONIC WITH ISOTONIC SALINE HYDROXYETHYL STARCH SOLUTION ON OXYGEN EXTRACTION CAPABILITIES DURING ENDOTOXIC SHOCK (1998) (30)
- Long-term Impact of Crystalloid versus Colloid Solutions on Renal Function and Disability-free Survival after Major Abdominal Surgery (2019) (30)
- The Acquisition of Multidrug-Resistant Bacteria in Patients Admitted to COVID-19 Intensive Care Units: A Monocentric Retrospective Case Control Study (2020) (30)
- How much oxygen in adult cardiac arrest? (2014) (30)
- ARDS of early or late onset: does it make a difference? (2010) (30)
- Neuraminidase alters red blood cells in sepsis (2009) (30)
- Toward less sedation in the intensive care unit: a prospective observational study. (2011) (29)
- Ethical principles in end-of-life decisions in different European countries. (2004) (29)
- Sepsis defi nitions: time for change (2013) (29)
- Beneficial effects of ethyl pyruvate in septic shock from peritonitis. (2007) (29)
- The pulmonary artery catheter: is it still alive? (2018) (29)
- C-reactive protein levels after cardiac arrest in patients treated with therapeutic hypothermia. (2014) (29)
- Early goal-directed therapy: do we have a definitive answer? (2016) (29)
- Metabolic effects of arginine addition to the enteral feeding of critically ill patients. (2001) (29)
- Fatal outcome after polytrauma: multiple organ failure or cerebral damage? (1998) (29)
- The impact of extracerebral organ failure on outcome of patients after cardiac arrest: an observational study from the ICON database (2016) (29)
- High mixed venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients. (2011) (29)
- Hydrochloric acid infusion for treatment of metabolic alkalosis: Effects on acid‐base balance and oxygenation (1985) (29)
- Epidemiology of severe sepsis in the intensive care unit. (2008) (29)
- High mixed venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients (2011) (29)
- Effects of Different Crystalloid Solutions on Hemodynamics, Peripheral Perfusion, and the Microcirculation in Experimental Abdominal Sepsis (2016) (28)
- Automated Titration of Vasopressor Infusion Using a Closed-loop Controller: In Vivo Feasibility Study Using a Swine Model (2019) (28)
- Prevalence and outcomes of infections in Brazilian ICUs: a subanalysis of EPIC II study. (2012) (28)
- A high-dose aminoglycoside regimen combined with renal replacement therapy for the treatment of MDR pathogens: a proof-of-concept study. (2016) (28)
- Nonelective surgery at night and in-hospital mortality: Prospective observational data from the European Surgical Outcomes Study (2015) (28)
- Can cardioplegia management influence cytokine responses during clinical cardiopulmonary bypass? (1999) (28)
- Acute liver dysfunction after cardiac arrest (2018) (28)
- Continuous hemofiltration in severe sepsis: is it beneficial? (1995) (28)
- The continuum of critical care (2019) (28)
- Calcium Administration for Cardiovascular Support in Critically Ill Patients: When Is It Indicated? (1995) (28)
- A new device for the prevention of pulmonary embolism in critically ill patients: Results of the European Angel Catheter Registry (2015) (28)
- Practical impact of a decision support for goal-directed fluid therapy on protocol adherence: a clinical implementation study in patients undergoing major abdominal surgery (2019) (28)
- The Durban World Congress Ethics Round Table Conference Report: II. Withholding or withdrawing of treatment in elderly patients admitted to the intensive care unit. (2014) (28)
- Optimal Adrenergic Support in Septic Shock Due to Peritonitis (2003) (27)
- Improved survival in critically ill patients: are large RCTs more useful than personalized medicine? No (2016) (27)
- Renal effects of dopamine: can our dream ever come true? (1994) (27)
- Effect of a Recombinant Human Soluble Thrombomodulin on Baseline Coagulation Biomarker Levels and Mortality Outcome in Patients With Sepsis-Associated Coagulopathy (2020) (27)
- The Future of Critical Care Medicine: Integration and Personalization (2016) (27)
- Modulation of Dietary Lipid Composition During Acute Respiratory Distress Syndrome: Systematic Review and Meta-Analysis. (2015) (27)
- Evolution of insulin sensitivity and its variability in out-of-hospital cardiac arrest (OHCA) patients treated with hypothermia (2014) (27)
- Hemodynamic Effects of Glibenclamide During Endotoxemia: Contrasting Findings In Vitro Versus In Vivo (2003) (27)
- The fluid challenge (2020) (27)
- Dobutamine increases cerebral blood flow velocity and jugular bulb hemoglobin saturation in septic patients. (1997) (27)
- Steroids in sepsis: another swing of the pendulum in our clinical trials (2008) (27)
- Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels (2014) (27)
- Extracorporeal Organ Support: From Technological Tool to Clinical Strategy Supporting Severe Organ Failure. (2017) (27)
- Effects of dobutamine on hepato-splanchnic hemodynamics in an experimental model of hyperdynamic endotoxic shock. (2001) (27)
- Polymyxin B hemoperfusion and mortality in abdominal septic shock. (2009) (26)
- Feasibility of closed-loop titration of norepinephrine infusion in patients undergoing moderate- and high-risk surgery. (2019) (26)
- Transfusion in the exsanguinating Jehovah's Witness patient--the attitude of intensive-care doctors. (1991) (26)
- End-points of resuscitation: arterial blood pressure, oxygen delivery, blood lactate, or...? (2005) (26)
- Expert Panel: The use of the pulmonary artery catheter (1991) (26)
- Role of iron in anaemic critically ill patients: it's time to investigate! (2004) (26)
- The impact of diastolic blood pressure values on the neurological outcome of cardiac arrest patients. (2018) (26)
- Fluid management: the pharmacoeconomic dimension (2000) (26)
- Oxygen uptake/oxygen supply dependency: Fact or fiction? (1995) (26)
- Is the Current Management of Severe Sepsis and Septic Shock Really Evidence Based? (2006) (26)
- Effects of norepinephrine and dobutamine on oxygen transport and consumption in a dog model of endotoxic shock (1993) (26)
- Cardiogenic Shock with Stunned Myocardium during Triple-H Therapy Treated with Intra-aortic Balloon Pump Counterpulsation (2009) (26)
- The Intensive care unit specialist: Report from the Task Force of World Federation of Societies of Intensive and Critical Care Medicine. (2016) (26)
- Equilibrating SSC guidelines with individualized care (2021) (26)
- Pneumonia-induced sepsis and gut injury: effects of a poly-(ADP-ribose) polymerase inhibitor. (2005) (26)
- The relationship between oxygen demand, oxygen uptake, and oxygen supply (2005) (25)
- Research in Extracorporeal Life Support: A Call to Action. (2018) (25)
- Effect of selective decontamination on antibiotic resistance. (2011) (25)
- An Uncalibrated Pulse Contour Method to Measure Cardiac Output During Aortic Counterpulsation (2011) (25)
- FLUID RESUSCITATION: COLLOIDS VS CRYSTALLOIDS (2007) (25)
- Dichloroacetate administration in the treatment of endotoxin shock. (1990) (25)
- Control of hypertension in the critically ill: a pathophysiological approach (2013) (25)
- Recommended b-lactam regimens are inadequate in septic patients treated with continuous renal replacement therapy (2011) (25)
- Amrinone administration in endotoxin shock. (1988) (25)
- Anemia in sepsis: the importance of red blood cell membrane changes (2007) (25)
- Prediction of Postoperative Complications After Urgent Laparotomy by Intraperitoneal Microdialysis: A Pilot Study (2006) (25)
- Blood Warming during Hemofiltration Can Improve Hemodynamics and Outcome in Ovine Septic Shock (2006) (25)
- Arginine vasopressin in advanced vasodilatory shock. (2003) (25)
- Failure to Improve during First Day of Therapy Is Predictive of 28-Day Mortality in Severe Sepsi (2003) (25)
- The effects of dopamine on the respiratory system: friend or foe? (2007) (25)
- Intensive care medicine in 2050: NEWS for hemodynamic monitoring (2017) (24)
- Incidence of acute renal failure in the intensive care unit. (2001) (24)
- Microcirculatory abnormalities in patients with severe influenza A (H1N1) infection (2010) (24)
- Coagulopathy induced by hydroxyethyl starch. (1997) (24)
- Endocrine support in the critically ill. (2002) (24)
- Fluids for resuscitation. (1991) (24)
- Pharmacokinetics of the nitric oxide synthase inhibitor L‐NG‐methylarginine hydrochloride in patients with septic shock (1999) (24)
- EuSOS: European surgical outcomes study. (2011) (24)
- Serial blood lactate levels reflect both lactate production and clearance. (2015) (24)
- Dopamine versus norepinephrine: is one better? (2009) (24)
- Ventilator-associated pneumonia. (2004) (24)
- Current use of inotropes in circulatory shock (2021) (23)
- Administration of Nebivolol After Coronary Artery Bypass in Patients with Altered Left Ventricular Function (1993) (23)
- Effect of a Perioperative Intra-Aortic Balloon Pump in High-Risk Cardiac Surgery Patients: A Randomized Clinical Trial (2018) (23)
- A prospective evaluation of the Infection Probability Score (IPS) in the intensive care unit. (2008) (23)
- The pulmonary artery catheter (2012) (23)
- Treatment limitations in the era of ECMO. (2017) (23)
- Empirical models for dosage optimization of four beta-lactams in critically ill septic patients based on therapeutic drug monitoring of amikacin. (2010) (23)
- The rise and fall of drotrecogin alfa (activated). (2012) (23)
- Hemodynamic effects of 6% and 10% hydroxyethyl starch solutions versus 4% albumin solution in septic patients. (2008) (23)
- Individual gene expression and personalised medicine in sepsis. (2016) (23)
- Inflammatory response to cardiopulmonary bypass (1999) (23)
- Atropine administration in experimental electromechanical dissociation. (1992) (23)
- Impairment of &bgr;-Adrenergic Signaling in Healthy Peripheral Blood Mononuclear Cells Exposed to Serum from Patients with Septic Shock: Involvement of the Inhibitory Pathway of Adenylyl Cyclase Stimulation (2003) (23)
- Infections and use of antibiotics in patients admitted for severe acute pancreatitis: data from the EPIC II study. (2014) (23)
- EFFECTS OF DEXAMETHASONE ON MACROPHAGE MIGRATION INHIBITORY FACTOR PRODUCTION IN SEPSIS (2006) (23)
- Withholding and withdrawing life prolonging treatment in the intensive care unit: a current European perspective (2004) (23)
- INFLUENCE OF ANTACID TREATMENT ON THE TRACHEAL FLORA IN MECHANICALLY VENTILATED PATIENTS (1982) (22)
- Current practice and evolving concepts in septic shock resuscitation (2021) (22)
- Does aprotinin influence the inflammatory response to cardiopulmonary bypass in patients? (2003) (22)
- The Sepsis Text (2002) (22)
- How to select an antifungal agent in critically ill patients. (2013) (22)
- Daily evaluation of organ function during renal replacement therapy in intensive care unit patients with acute renal failure. (2006) (22)
- Important issues in the design and reporting of clinical trials in severe sepsis and acute lung injury. (2008) (22)
- Hepato-splanchnic blood flow and oxygen extraction capabilities during experimental tamponade: effects of endotoxin. (1999) (22)
- We should avoid the term “fluid overload” (2018) (22)
- Renal autoregulation and blood pressure management in circulatory shock (2018) (22)
- The hospital of tomorrow in 10 points (2017) (22)
- Acute kidney injury, acute lung injury and septic shock: how does mortality compare? (2011) (22)
- Modifications in Erythrocyte Membrane Protein Content Are Not Responsible for the Alterations in Rheology Seen in Sepsis (2012) (22)
- Correction: Management of bleeding following major trauma: a European guideline (2007) (22)
- An international perspective on hospitalized patients with viral community-acquired pneumonia (2018) (22)
- Prevention and management of thrombosis in hospitalised patients with COVID-19 pneumonia (2021) (21)
- A REGISTRY OF PATIENTS TREATED WITH DROTRECOGIN ALFA (ACTIVATED) IN BELGIAN INTENSIVE CARE UNITS - AN OBSERVATIONAL STUDY (2008) (21)
- The International Sepsis Forum's frontiers in sepsis: high cardiac output should be maintained in severe sepsis (2003) (21)
- THE HEPATOSPLANCHNIC CONTRIBUTION TO HYPERLACTATEMIA IN ENDOTOXIC SHOCK: EFFECTS OF TISSUE ISCHEMIA (2004) (21)
- Sublingual Microcirculatory Effects of Enalaprilat in an Ovine Model of Septic Shock (2011) (21)
- Hypophosphatemia after cardiothoracic surgery (2004) (21)
- How can assessing hemodynamics help to assess volume status? (2022) (21)
- The importance of airway and lung microbiome in the critically ill (2020) (21)
- Proceedings of resources for optimal care of acute care and emergency surgery consensus summit Donegal Ireland (2017) (21)
- Effects of dobutamine on the relationship between oxygen consumption and delivery in healthy volunteers: comparison with sodium nitroprusside. (1996) (21)
- Computer-assisted Individualized Hemodynamic Management Reduces Intraoperative Hypotension in Intermediate- and High-risk Surgery: A Randomized Controlled Trial (2021) (21)
- Erratum to: Albumin administration in the acutely ill: what is new and where next? (2014) (21)
- Critical care in Europe. (1997) (21)
- Randomized trial evaluating serial protein C levels in severe sepsis patients treated with variable doses of drotrecogin alfa (activated) (2010) (21)
- Sepsis, severe sepsis or sepsis syndrome: Need for clarification (2005) (21)
- Effects of dobutamine and norepinephrine on oxygen availability in tamponade‐induced stagnant hypoxia: A prospective, randomized, controlled study (1994) (21)
- Ketanserin, a serotonin antagonist. Administration in patients with acute respiratory failure. (1984) (21)
- Saline versus balanced solutions: are clinical trials comparing two crystalloid solutions really needed? (2016) (20)
- Blood glucose control in 2010: 110 to 150 mg/dL and minimal variability. (2010) (20)
- A reappraisal for the use of pulmonary artery catheters (2006) (20)
- Initial management of circulatory shock as prevention of MSOF. (1989) (20)
- Modifications of red blood cell shape and glycoproteins membrane content in septic patients. (2003) (20)
- POTENTIAL THERAPEUTIC VALUE OF LAZAROIDS IN ENDOTOXEMIA AND OTHER FORMS OF SEPSIS (1997) (20)
- The pros and cons of hydroxyethyl starch solutions. (2007) (20)
- PENTOXIFYLLINE IMPROVES THE TISSUE OXYGEN EXTRACTION CAPABILITIES DURING ENDOTOXIC SHOCK (1994) (20)
- Use of albumin in the intensive care unit (2002) (20)
- Acute Kidney Injury After Subarachnoid Hemorrhage (2017) (20)
- Cardiac output measurement: is least invasive always the best? (2002) (20)
- Non-heart-beating donation: ethical aspects. (2009) (20)
- Development of acute kidney injury during continuous infusion of vancomycin in septic patients (2013) (20)
- Lactate and base deficit are predictors of mortality in critically ill patients with cancer (2011) (20)
- Lactate levels in critically ill patients (1995) (20)
- Effects of dobutamine and prostacyclin on cerebral blood flow velocity in septic patients. (1994) (20)
- Emerging therapies for the treatment of sepsis (2015) (19)
- Ten big mistakes in intensive care medicine (2015) (19)
- Systemic oxygen extraction can be improved during repeated episodes of cardiac tamponade. (1993) (19)
- Manual versus Automated moNitoring Accuracy of GlucosE II (MANAGE II) (2016) (19)
- Placement of the nebulizer before the humidifier during mechanical ventilation: Effect on aerosol delivery. (2009) (19)
- Clinical trial research in focus: rethinking trials in sepsis. (2017) (19)
- Is endotoxin-induced hypotension related to nitric oxide formation? (1994) (19)
- Evaluation of organ failure: we are making progress (2000) (19)
- Hypotension and a positive fluid balance are associated with delirium in patients with shock (2018) (19)
- TIME COURSE OF IRON METABOLISM IN CRITICALLY ILL PATIENTS (2013) (19)
- Definition and pathogenesis of septic shock. (1996) (19)
- No relationship between red blood cell distribution width and microcirculatory alterations in septic patients. (2017) (19)
- Thrombus formation on a calcific and severely stenotic bicuspid aortic valve. (1997) (19)
- A ‘Shock Room’ for Early Management of the Acutely Ill (2006) (19)
- Efficacy and safety of recombinant human soluble thrombomodulin in patients with sepsis‐associated coagulopathy: A systematic review and meta‐analysis (2020) (19)
- The potential role of auditory evoked potentials to assess prognosis in comatose survivors from cardiac arrest. (2017) (19)
- Determinants of time to death in hospital in critically ill patients around the world (2016) (19)
- Vitamin C for Sepsis and Acute Respiratory Failure. (2020) (19)
- Prostaglandin E1 increases oxygen extraction capabilities in experimental sepsis. (1994) (19)
- Which carries the biggest risk: Anaemia or blood transfusion? (2015) (18)
- Early Effects of Enteral Urea on Intracranial Pressure in Patients With Acute Brain Injury and Hyponatremia (2017) (18)
- Mortality after surgery in Europe – Authors' reply (2013) (18)
- EPIC II: sepsis around the world. (2008) (18)
- THE MICROCIRCULATION IN CRITICALLY-ILL PATIENTS (2007) (18)
- Guidelines for training in intensive care medicine (2006) (18)
- Norepinephrine administration in septic shock: how much is enough? (2002) (18)
- Altered liver function in patients undergoing veno-arterial extracorporeal membrane oxygenation (ECMO) therapy. (2017) (18)
- A closed-chest model for the study of electromechanical dissociation of the heart in dogs. (1982) (18)
- ISCHEMIC CONDITIONING PROTECTS THE MICROCIRCULATION, PRESERVES ORGAN FUNCTION, AND PROLONGS SURVIVAL IN SEPSIS (2015) (18)
- Transfusion triggers: getting it right! (2012) (18)
- Nitroglycerin for septic shock (2003) (18)
- Should red cell transfusion be individualized? Yes (2015) (18)
- Dear Sirs, What is your PCT? (2000) (18)
- Guidelines for a training programme in intensive care medicine (1996) (18)
- Precision medicine for COVID-19: a call for better clinical trials (2020) (18)
- Nonhematological organ dysfunction and positive fluid balance are important determinants of outcome in adults with severe dengue infection: a multicenter study from India. (2011) (18)
- Potential uses of hemoglobin-based oxygen carriers in critical care medicine. (2009) (17)
- Microvascular reactivity is altered early in patients with acute respiratory distress syndrome (2016) (17)
- Novel Interventions: What's New and the Future. (2018) (17)
- Blood lactate levels in sepsis: in 8 questions (2021) (17)
- How much centralization of critical care services in the era of telemedicine? (2019) (17)
- Herpes virus infection, an unusual source of adult respiratory distress syndrome. (1985) (17)
- COVID-19: it is all about sepsis (2021) (17)
- ANGIOGRAPHY IN GASTROINTESTINAL BLEEDING (1982) (17)
- Should all patients with sepsis receive anticoagulation? Yes (2017) (17)
- Initial and Delayed Onset of Acute Respiratory Failure: Factors Associated with Development and Outcome (2006) (17)
- Vasopressin in hypotensive and shock states. (2006) (17)
- Do trials that report a neutral or negative treatment effect improve the care of critically ill patients? No (2018) (17)
- The Harmful Effects of Hypertonic Sodium Lactate Administration in Hyperdynamic Septic Shock (2016) (17)
- Influence of incentive spirometry on pulmonary volumes after laparotomy. (1983) (17)
- Arterial baroreflex control of the sinus node during dobutamine exercise stress testing. (1999) (17)
- Near infrared spectroscopy (NIRS) to assess the effects of local ischemic preconditioning in the muscle of healthy volunteers and critically ill patients. (2015) (17)
- Are multiple blood transfusions really a cause of acute respiratory distress syndrome? (2007) (16)
- Effects of dobutamine on gut mucosal nitric oxide production during endotoxic shock in rabbits. (2009) (16)
- Use of methylprednisolone in patients following acute myocardial infarction. Hemodynamic and metabolic effects. (1981) (16)
- From Early Goal-Directed Therapy to Late(r) Scvo2 Checks. (2018) (16)
- Monitoring of pulse pressure variation using a new smartphone application (Capstesia) versus stroke volume variation using an uncalibrated pulse wave analysis monitor: a clinical decision making study during major abdominal surgery (2019) (16)
- Cardiovascular effects of moderate normovolaemic haemodilution during enflurane-nitrous oxide anaesthesia in man. (1995) (16)
- Glucose and Lactate Concentrations in Cerebrospinal Fluid After Traumatic Brain Injury (2019) (16)
- International integrated database for the evaluation of severe sepsis and drotrecogin alfa (activated) therapy: 28-day survival and safety. (2007) (16)
- End-of-life practice in Belgium and the new euthanasia law (2006) (16)
- IL-1ra administration does not improve cardiac function in patients with severe sepsis. (1999) (16)
- Steroids in cardiopulmonary bypass. (2000) (16)
- Automated closed-loop versus manually controlled norepinephrine infusion in patients undergoing intermediate- to high-risk abdominal surgery: a randomised controlled trial. (2020) (16)
- Electromechanical dissociation after ventricular fibrillation: prevention with calcium-entry blockers. (1984) (16)
- Withholding or withdrawing of treatment in elderly patients admitted to the intensive care unit (2014) (16)
- Skin microcirculatory reactivity assessed using a thermal challenge is decreased in patients with circulatory shock and associated with outcome (2018) (16)
- Normovolemic hemodilution improves oxygen extraction capabilities in endotoxic shock. (2001) (16)
- Issues in contemporary fluid management (2000) (16)
- Intensive care medicine in 2050: the future of ICU treatments (2017) (16)
- Organ Dysfunction as an Outcome Measure: The Sofa Score (1997) (16)
- Brain tissue oxygenation guided therapy and outcome in non-traumatic subarachnoid hemorrhage (2021) (15)
- What are the optimum components in a care bundle aimed at reducing post-operative pulmonary complications in high-risk patients? (2018) (15)
- Does central venous oxygen saturation accurately reflect mixed venous oxygen saturation? Nothing is simple, unfortunately (2005) (15)
- Red Cell Distribution Width After Subarachnoid Hemorrhage (2017) (15)
- Cardiopulmonary Interactions in Acute Respiratory Failure (1987) (15)
- Getting Critical About Constipation (2015) (15)
- Evidence supports the superiority of closed ICUs for patients and families: Yes (2016) (15)
- Effect of empiric antibiotic treatment on plasma endotoxin activity in septic patients (2014) (15)
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- Intraoperative hypotension during liver transplant surgery is associated with postoperative acute kidney injury: a historical cohort study (2021) (14)
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- The available clinical tools: Oxygen derived variables, lactate and pHi (1998) (13)
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- Using arterial-venous oxygen difference to guide red blood cell transfusion strategy (2020) (13)
- Increased mortality in critically ill patients with mild or moderate hyperbilirubinemia☆,☆☆ (2017) (13)
- Ceftazidime- and Imipenem-Induced Endotoxin Release During Treatment of Gram-Negative Infections (2001) (13)
- Baseline Characteristics and Survival of Adult Severe Sepsis Patients Treated With Drotrecogin Alfa (Activated) in a Global, Single-Arm, Open-Label Trial (ENHANCE) (2003) (13)
- Comparison of the efficacy and safety of FP-1201-lyo (intravenously administered recombinant human interferon beta-1a) and placebo in the treatment of patients with moderate or severe acute respiratory distress syndrome: study protocol for a randomized controlled trial (2017) (13)
- Increase in oxygen supply during experimental septic shock: the effects of dobutamine versus dopexamine (1989) (13)
- Which therapeutic interventions in critical care medicine have been shown to reduce mortality in prospective, randomized, clinical trials? A survey of candidates for the Belgian Board Examination in Intensive Care Medicine (2000) (13)
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- Sepsis diagnosis and management: work in progress. (2006) (12)
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- Use of Maximum End-Tidal CO2 Values to Improve End-Tidal CO2 Monitoring Accuracy (2011) (12)
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- SUBLINGUAL PCO2 MONITORING IN PATIENTS WITH SEPTIC SHOCK: 65 (2002) (11)
- Difficulty interpreting the results of some trials: the case of therapeutic hypothermia after pediatric cardiac arrest (2015) (11)
- How stable is a "stable" cardiac output? (1994) (11)
- Use of orthogonal polarization spectral imaging in intensive care (2000) (11)
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- Doctors' perceptions of the effects of interventions tested in prospective, randomised, controlled, clinical trials: results of a survey of ICU physicians (2001) (11)
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- MODELS TO STUDY THE RELATION BETWEEN OXYGEN CONSUMPTION AND OXYGEN DELIVERY DURING AN ACUTE REDUCTION IN BLOOD FLOW: COMPARISON OF BALLOON FILLING IN THE INFERIOR VENA CAVA, TAMPONADE, AND HEMORRHAGE (1995) (11)
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- Hemodynamic Monitoring and Support (2021) (8)
- Comparison of dopamine and norepinephrine in shock (2010) (8)
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- COMPARATIVE EFFECTS OF DOPAMINE AND DOBUTAMINE ON RIGHT VENTRICULAR FUNCTION IN CRITICALLY ILL PATIENTS (1986) (7)
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- Platelet indices and outcome after cardiac arrest (2018) (6)
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- Still a (valuable) place for the pulmonary artery catheter. (2014) (5)
- Treatment of lactic acidosis. (1984) (5)
- Pandemic-Related Submissions: The Challenge of Discerning Signal Amidst Noise. (2020) (5)
- Effects of a Novel Anticoagulant Compound (TV7130) in an Ovine Model of Septic Shock (2010) (5)
- Is ARDS usually associated with right ventricular dysfunction or failure? (1995) (5)
- Yearbook of Intensive Care and Emergency Medicine 2001 (2001) (5)
- Glucocorticoid administration in sepsis and septic shock: time for a paradigm change? (2014) (5)
- THERMODILUTION MEASUREMENT OF RIGHT VENTRICULAR EJECTION FRACTION: IMPLICATIONS IN SEPTIC PATIENTS (1987) (5)
- The sicker the patient, the more likely that transfusion will be beneficial. (2017) (5)
- Candida infections in surgical intensive care unit patients (2001) (5)
- [The intensive care department]. (2002) (4)
- Practical aspects of oxygen transport: conclusions and recommendations of the Roundtable Conference (1990) (4)
- No room for hyperoxia or hypertonic saline in septic shock. (2017) (4)
- Do we need a dopaminergic agent in the management of the critically ill? (1990) (4)
- Critical care medicine in 2050: less invasive, more connected, and personalized. (2019) (4)
- Intravascular Volume Assessment in the Critically Ill Patient. (2019) (4)
- Treatment of intraparenchymal hypertension with hyperosmotic therapy: hypertonic saline 7.45% vs. mannitol 20. (2016) (4)
- Monitoring Cardiac Output (2003) (4)
- Yearbook of Intensive Care and Emergency Medicine 1999 (1999) (4)
- The Immune Response in Critical Illness: Excessive, Inadequate or Dysregulated (2002) (4)
- Evaluation of a new smartphone optical blood pressure application (OptiBP™) in the post-anesthesia care unit: a method comparison study against the non-invasive automatic oscillometric brachial cuff as the reference method (2022) (4)
- Effect of Ibuprofen and Diethylcarbamazine on the Hemodynamic and Inflammatory Response to Endotoxin in the Dog (2000) (4)
- Assessing Cellular Responses in Sepsis☆ (2014) (4)
- Arterio-Venous CO2 Gradients: Clinical Studies (1993) (4)
- Intensive care medicine: Annual update 2007 (2007) (4)
- Relationship between Microcirculatory Perfusion and Arterial Elastance: A Pilot Study (2019) (4)
- Intensive Care and Emergency Medicine (1984) (4)
- Multiple-organ failure and the gut (1996) (4)
- Current management of Gram-negative septic shock (2018) (4)
- We've made progress in the treatment of sepsis, so do we still need sepsis trials? (2013) (4)
- Euthanasia in the intensive care unit. (1993) (4)
- European participation in major intensive care journals (2006) (4)
- Aortic luminal thrombus and intramural hematoma after cardiopulmonary resuscitation (2013) (4)
- Administration of Tetrahydrobiopterin (BH4) Protects the Renal Microcirculation From Ischemia and Reperfusion Injury (2017) (4)
- Big data are here to stay! (2019) (4)
- How have red blood transfusion practices changed in critically ill patients? A comparison of the ICON and ABC studies conducted 13 years apart (2020) (4)
- Erratum to: Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) (2017) (4)
- Systematic Review and Meta-Analysis of Effects of Transfusion on Hemodynamic and Oxygenation Variables. (2019) (4)
- Effects of acute ethanol intoxication in an ovine peritonitis model (2018) (4)
- A complete system for transportation of critically ill patients with acute cardiorespiratory failure. (1983) (4)
- Measure, interpret, apply - the MIA rule in critical care monitoring. (2016) (4)
- ESICM LIVES 2016: part three (2016) (4)
- Association of anemia and transfusions with outcome after subarachnoid hemorrhage (2021) (4)
- ESICM LIVES 2016: part three (2016) (4)
- ESICM LIVES 2016: part three (2016) (4)
- EFFECTS OF FLUID CHALLENGE ON ARTERIAL-GASTRIC CO2 GRADIENT IN SEPTIC PATIENTS (1998) (4)
- Acetate versus bicarbonate for hemodialysis in critically ill patients (1986) (4)
- ESICM LIVES 2016: part three (2016) (4)
- The World Trade Center Attack: Lessons for all aspects of health care (2001) (4)
- Control of Postoperative Hypotension Using a Closed-Loop System for Norepinephrine Infusion in Patients After Cardiac Surgery: A Randomized Trial (2022) (4)
- SUBLINGUAL MICROCIRCULATION REFLECTS INTESTINAL MUCOSAL MICROCIRCULATION IN SEPSIS: A QUANTITATIVE ANALYSIS.: 191-S (2005) (4)
- ESICM LIVES 2016: part three (2016) (4)
- The pathophysiology of septic shock. (1982) (4)
- ESICM LIVES 2016: part three (2016) (4)
- INFUSION OF GLUCOSE AND INSULIN IN CIRCULATORY SHOCK (1981) (4)
- ESICM LIVES 2016: part three (2016) (4)
- The cardiac index/oxygen extraction diagram to assess hemodynamic status (1994) (4)
- High-flow oxygen cannula: a very effective method to correct severe hypoxemia. (2015) (4)
- The Haldane effect--an explanation for increasing gastric mucosal PCO2 gradients? (2000) (4)
- The Prognostic Role of Lactate Concentrations after Aneurysmal Subarachnoid Hemorrhage (2020) (4)
- Anaemia and blood transfusion in critical care (ABC) survey: Organ function and mortality in transfused patients (2001) (4)
- Pulse pressure variation using a novel smartphone application (Capstesia) versus invasive pulse contour analysis in patients undergoing cardiac surgery: a secondary analysis focusing on clinical decision making (2019) (4)
- The Sequential Organ Failure Assessment (SOFA) Score: has the time come for an update? (2023) (4)
- The effects of acute renal denervation on kidney perfusion and metabolism in experimental septic shock (2017) (4)
- Yearbook of Intensive Care and Emergency Medicine 1997 (2014) (4)
- Cerebral oximetry to adjust cerebral and systemic circulation after cardiac arrest (2013) (4)
- Limited effects of activated protein C on red blood cell deformability. (2013) (4)
- The Protective Role of Interleukin-10 in Sepsis (1994) (4)
- Plasma fibrinolysis is related to the degree of organ dysfunction but not to the concentration of von Willebrand Factor in critically ill patients (2009) (4)
- Perioperative Critical Care Cardiology (2007) (4)
- Mechanical Ventilation and Weaning (2002) (4)
- Comparison of estimation of cardiac output using an uncalibrated pulse contour method and echocardiography during veno-venous extracorporeal membrane oxygenation (2019) (4)
- Yearbook of Intensive Care and Emergency Medicine 2000 (2000) (4)
- Oxygen delivery in the critically ill. (1991) (4)
- Sepsis in the ICU: who needs progress? (2006) (4)
- Choice of Fluids and Vasoactive Agents (1987) (4)
- Sedation in traumatic brain injury : Avoid etomidate. Author's reply (2005) (4)
- Myocardial effects of angiotensin II compared to norepinephrine in an animal model of septic shock (2022) (4)
- Effect of a Recombinant Human Soluble Thrombomodulin on Baseline Coagulation Biomarker Levels and Mortality Outcome in Patients With Sepsis-Associated Coagulopathy. (2020) (4)
- Administration of the calcium agonist BAY K 8644 in endotoxic shock. (1991) (4)
- Potentiation of the effects of enoximone by a dobutamine infusion (2004) (4)
- SOFA Score: A Keystone for Grading Multiple Organ Dysfunction (2008) (4)
- Measurement of ventricular ejection fraction in the acutely ill. (1988) (4)
- Do I have a conflict of interest? No (2018) (4)
- Implementation of the Surviving Sepsis Campaign guidelines (2006) (3)
- An international perspective on the frequency, perception of utility, and quality of interprofessional rounds practices in intensive care units. (2020) (3)
- Cardiorespiratory Physiotherapy around the Clock: Experience at a University Hospital (2016) (3)
- Sepsis definitions. (2002) (3)
- The Relationship Between Heart Rate and Body Temperature in Critically Ill Patients (2021) (3)
- Collinearity and multivariable analysis: response to comments by Claret et al. (2016) (3)
- The Prognostic Value of Brain Dysfunction in Critically Ill Patients with and without Sepsis: A Post Hoc Analysis of the ICON Audit (2021) (3)
- Thinking forward: promising but unproven ideas for future intensive care (2019) (3)
- 6th International Symposium on Intensive Care and Emergency Medicine (1986) (3)
- Anemia in the ICU (2000) (3)
- Carbon dioxide management after cardiac arrest: quite a complex issue. (2013) (3)
- Update on sepsis guidelines: What has changed (2008) (3)
- Drotrecogin alfa (activated) in the treatment of severe sepsis (2006) (3)
- A Randomized, Double-Blind, Placebo-Controlled, Phase-2B Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients with Sepsis and Suspected Disseminated Intravascular Coagulation (2012) (3)
- 62: SELEPRESSIN, A NOVEL SELECTIVE VASOPRESSIN V1A AGONIST, REDUCES NOREPINEPHRINE REQUIREMENTS AND SHORTENS DURATION OF ORGAN DYSFUNCTION IN SEPTIC SHOCK PATIENTS (2012) (3)
- Continuous non-invasive haemodynamic monitoring in patients having surgery: Valuable tool or superfluous toy? (2020) (3)
- Baseline characteristics of patients enrolled in the phase III trial of rhAPC in severe sepsis (2000) (3)
- Correction to: Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis (2018) (3)
- The platelet-activating factor antagonist BB-882 does not improve tissue oxygen extraction in endotoxic shock. (1998) (3)
- International participation in major intensive care journals (1996) (3)
- Infection control in the intensive care unit (2004) (3)
- Hemodynamic Monitoring (1989) (3)
- The challenge of early identification of the hospital patient at risk of septic complications. (2017) (3)
- Sepsis in Intensive Care Unit Patients : Worldwide data from the ICON audit (2018) (3)
- Elevated endocan levels are associated with development of renal failure in ARDS patients (2015) (3)
- Drotrecogin alpha (activated): the treatment for severe sepsis? (2007) (3)
- Pandemic-Related Submissions: The Challenge of Discerning Signal Amidst Noise (2020) (3)
- Defining a Clinical Syndrome of Systemic Inflammation (2000) (3)
- An increase in skin blood flow induced by fluid challenge is associated with an increase in oxygen consumption in patients with circulatory shock. (2022) (3)
- ESICM LIVES 2016: part three : Milan, Italy. 1-5 October 2016. (2016) (3)
- Ethics roundtable debate: Child with severe brain damage and an underlying brain tumour (2004) (3)
- TREATMENT OF SEPTIC SHOCK WTTH AMRINONE: AN EXPERIMENTAL STUDY (1986) (3)
- Effects of Methylprednisolone on P50, 2,3 Diphosphoglycerate and Arteriovenous Oxygen Difference in Acute Myocardial Infarction (1980) (3)
- The Berlin definition met our needs: not sure (2016) (3)
- Another antiendotoxin strategy to be added to the list. (1997) (3)
- Endotoxin shock model in the dog: a reevaluation. (1987) (3)
- Hypertonic Saline in Human Sepsis: A Systematic Review of Randomized Controlled Trials. (2019) (3)
- Correction: Is the Current Management of Severe Sepsis and Septic Shock Really Evidence Based? (2006) (3)
- Critical Care: a good scientific citizen just got better (2003) (3)
- Pharmacological interventions in acute respiratory failure (1987) (3)
- Defining sepsis (with or without positive blood cultures). (2017) (3)
- Right ventricular function in septic shock (2004) (3)
- Appropriate care for the elderly in the ICU (2021) (3)
- Septic shock: incidence, mortality and hospital readmission rates in French intensive care units from 2014 to 2018. (2022) (3)
- Candida and aspergillus infections in critically ill patients (2002) (3)
- The Brussels Sedation Scale: Use of a Simple Clinical Sedation Scale Can Avoid Excessive Sedation in Patients Undergoing Mechanical Ventilation in the Intensive Care Unit (2000) (3)
- Surviving Sepsis Campaign: Guideline Clarification (2008) (3)
- Who should manage the intensive care unit (2001) (3)
- Postoperative salmonella meningitis: successful treatment with cefotaxime. (1985) (3)
- Quick sequential organ failure assessment: big databases vs. intelligent doctors. (2016) (3)
- The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition (2023) (3)
- What conclusions should be drawn between critical care physician management and patient mortality in the intensive care unit? (2008) (3)
- Euglycemic Hyperinsulinemia in Severe Sepsis and Septic Shock (2006) (3)
- Design and Evaluation of a Wireless Electrocardiogram Monitor in an Operating Room: A Pilot Study. (2019) (3)
- Tissue oxygenation in ARDS (1993) (3)
- The effects of balloon filling into the inferior vena cava on the Relationship (1992) (3)
- Ten areas for ICU clinicians to be aware of to help retain nurses in the ICU (2022) (3)
- Yearbook of Intensive Care and Emergency Medicine 2005 (2005) (3)
- Technical and psychological complications of high-frequency jet ventilation (2004) (3)
- Use and misuse of vasoactive agents in acute circulatory failure. (1984) (3)
- Sepsis is a global burden to human health: incidences are underrepresented (2018) (3)
- Therapeutic aspects of oxygen delivery (1997) (3)
- Critical care in the 21st century: preparation, preparation, and preparation (2004) (3)
- Plasma colloid osmotic pressure (1998) (2)
- Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts (2021) (2)
- Pragmatic studies for acute kidney injury: Consensus report of the Acute Disease Quality Initiative (ADQI) 19 Workgroup (2018) (2)
- Information needs of the ICU patient: a Belgian experience (2000) (2)
- Relation Between Oxygen Consumption and Oxygen Delivery After Cardiac Surgery: Beware Mathematical Coupling (1995) (2)
- Optimising cardiac output (1991) (2)
- Cortical and subcortical grey matter morphometry for neuroprognostication after cardiac arrest (2016) (2)
- Are the concepts of SIRS and MODS useful in sepsis (2010) (2)
- Editorial: Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis: Clinical trials in immunotherapy for sepsis: Why have the results been so disappointing? (1996) (2)
- Lactate and biochemical indices of oxygenation (1997) (2)
- Combatting Resistance in Intensive Care: The Multimodal Approach of the Spanish ICU “Zero Resistance” Program (2015) (2)
- Editorial Evidence-based medicine journal club (2004) (2)
- Comprar Textbook of Critical Care, 6th Edition Expert Consult Premium Edition - Enhanced Online Features and Print | Mitchell P. Fink | 9781437713671 | Saunders (2011) (2)
- Specific therapies of biguanide-induced lactic acidosis. (1998) (2)
- ESICM LIVES 2016: part one (2016) (2)
- Intrahepatocellular erythrocyte inclusions and increased calcium precipitation in canine endotoxic shock. (1997) (2)
- The European ICU nurse profile (1998) (2)
- Impact of reimbursement schemes on quality of care: a European perspective. (2012) (2)
- Resuscitation of the microcirculation with hemoglobin-based oxygen carriers following hemorrhage (2004) (2)
- A640 EFFECTS OF HEMATOCRIT ON 02 TISSUE EXTRACTION CAPABILITIES (1990) (2)
- ventriculostomy infections. Authors' reply (2006) (2)
- Hypertonic Saline in Human Sepsis: A Systematic Review of Randomized Controlled Trials. (2019) (2)
- Critical Care – 10 years on (2006) (2)
- The Importance of Acute Respiratory Failure in the ICU (2005) (2)
- Drotrecogin alfa (activated) for severe sepsis: could we consider a shorter treatment period in patients with a favorable course? (2009) (2)
- The future of observational research and RCTs in transfusion medicine (2014) (2)
- 933: Beta-lactams overdosing is associated with electroencephalographic abnormalities during sepsis (2013) (2)
- Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts (2021) (2)
- Trombo a?rtico intraluminal e hematoma intramural ap?s manobra de ressuscita??o cardiopulmonar (2013) (2)
- Surviving Sepsis Campaign : Guideline Clarification. Authors' reply (2008) (2)
- Transfusion thresholds and red blood cells transfusion focused on tissue oxygenation. (2018) (2)
- Modulating the immune response in severe trauma (1992) (2)
- Definition, Monitoring, and Management of Shock States (2009) (2)
- Optimal meropenem concentrations to treat multi-drug (2012) (2)
- Pharmacological management of the pulmonary circulation in critically ill patients (2004) (2)
- Right ventricular function during pulmonary artery clamping : Effects of enflurane (1990) (2)
- COMBINATION OF BLOOD LACTATE LEVELS AND pHi IN SEVERE SEPSIS (1994) (2)
- BEDSIDE ASSESSMENT OF WHOLE BLOOD VISCOSITY IN CRITICALLY ILL PATIENTS.: 281 (2006) (2)
- Proteinuria in COPD Patients With and Without Respiratory Failure (2003) (2)
- Bronchopulmonary superinfections in the critically ill. (1987) (2)
- Pre-hospital Resuscitation INtra-arrest Cooling Effectiveness Survival – The PRINCESS Study (2015) (2)
- High-ProteinEnteralNutritionEnrichedWithImmune-Modulating Nutrients vs StandardHigh-ProteinEnteralNutrition andNosocomial Infections in the ICU A Randomized Clinical Trial (2014) (2)
- Understanding Hyperlactatemia in Human Sepsis: Are We Making Progress? (2019) (2)
- Clinico-pathological conference. Pheochromocytoma (1987) (2)
- Organ dysfunction scores in critical illness (2005) (2)
- Massive bleeding in polytrauma: how can we make progress? (2011) (2)
- Augmentation of Splanchnic Blood Flow (1995) (2)
- EFFECTS OF METHYLPREDNISOLONE ON OXYHEMOGLOBIN DISSOCIATION AFTER ACUTE MYOCARDIAL INFARCTION (1980) (2)
- Lactic Acidosis in the Critically Ill (2000) (2)
- Inotropic agents. (1993) (2)
- Absence of myocardial protection with prostacyclin during cardiac arrest. (1986) (2)
- An overview of gastric tonometry (2002) (2)
- Hemodynamic Monitoring, Pharmacologic Therapy, and Arrhythmia Management in Acute Congestive Heart Failure (1994) (2)
- Critical care--an all-encompassing specialty [editorial] (2013) (2)
- Hemofiltration in Sepsis and Septic Shock (1997) (2)
- Corrigendum to "C-reactive protein levels after cardiac arrest in patients treated with therapeutic hypothermia" [Resuscitation 85 (2014) 932-938]. (2016) (2)
- Surviving sepsis campaign guidelines 2008: Revisiting vasopressor recommendations (2008) (2)
- Cytokine Responses During Clinical Cardiopulmonary Bypass (1997) (2)
- Impact of conventional vs. goal-directed fluid therapy on urethral tissue perfusion in patients undergoing liver surgery: A pilot randomised controlled trial. (2021) (2)
- Selenocompounds and Sepsis: Redox Bypass Hypothesis: Part B- Selenocompounds in the Management of Early Sepsis. (2022) (2)
- Clinical value of suPAR, a new critical biomarker (2011) (2)
- On the verge of using an immune toolbox in the intensive care unit? (2017) (2)
- Effects of serotonin inhibition in air embolism in dogs. (1988) (2)
- Acetylcholine can totally reverse alterations in microvascular blood flow that occur in patients with septic shock (2001) (2)
- [International differences in end-of-life decisions]. (2007) (2)
- ESICM LIVES 2016: part two (2016) (2)
- BLOOD SELENIUM CONCENTRATIONS IN SEPTIC SHOCK DUE TO PERITONITIS (2006) (2)
- Current sepsis therapeutics (2022) (2)
- BRETYLIUM VS LIDOCAINE IN EXPERIMENTAL CPR (1988) (2)
- 560: A SIMPLE BEDSIDE SCORE TO PREDICT NEUROLOGICAL OUTCOME AFTER CPR (2012) (2)
- Current management of sepsis and septic shock (2016) (2)
- Geographic Variations in Use of Recommended Severe Sepsis Interventions Observed in PROGRESS Severe Sepsis Registry Data (2004) (2)
- Automated Pupillometry for Prediction of Electroencephalographic Reactivity in Critically Ill Patients: A Prospective Cohort Study (2022) (2)
- Intensive care medicine in 2050: towards critical care without central lines (2018) (2)
- Sepsis and Clinical Trials: a New Era in Anti-Sepsis Therapies (2002) (2)
- Initial Empirical Antibacterial Therapy of Ventilator-Associated Pneumonia (2006) (2)
- Clinical Fluid Therapy in the Perioperative Setting. (2017) (2)
- Peripheral Administration of Vasopressin for Catecholamine-Resistant Hypotension Complicated by Skin Necrosis (2006) (2)
- Avoiding underfeeding in severely ill patients – Authors' reply (2013) (2)
- THE EFFECTS OF CRYSTALLOIDS AND ALBUMIN ON MICROCIRCULATORY ALTERATIONS IN PATIENTS WITH SEVERE SEPSIS (2008) (2)
- Comparison of PROGRESS Severe Sepsis Registry Patients to INDEPTH Integrated Severe Sepsis Clinical Trial Database Placebo Patients (2004) (2)
- [Post-traumatic carotid-cavernous sinus fistula]. (1999) (2)
- Residual cerebral functioning in the vegetative state (2004) (2)
- 56: EFFECTS OF A HYDROXYETHYLSTARCH SOLUTION ON THE PLASMA ONCOTIC PRESSURE (1998) (2)
- Mild increases in plasma creatinine after intermediate to high-risk abdominal surgery are associated with long-term renal injury (2021) (2)
- Thermodilution for measurement of cardiac output during artificial ventilation (2004) (2)
- Critical Care Cardiology in the Perioperative Period (2001) (2)
- The acquisition of Multi-drug resistant bacteria in patients admitted to COVID-19 intensive care units: a monocentric retrospective case control study (2020) (1)
- Appréciation de la sévérité de l'affection des patients admis en réanimation par la mesure de la CRP (2015) (1)
- Evaluation of a novel optical smartphone blood pressure application: a method comparison study against invasive arterial blood pressure monitoring in intensive care unit patients (2022) (1)
- The following is the abstract of the article discussed in the subsequent letter:. (2005) (1)
- CPR in the trauma patient: indications and contraindications. (1999) (1)
- 586: Crp Levels After Cardiac Arrest. (2012) (1)
- 199: TREATMENT OF INTRA-PARENCHYMAL HYPERTENSION WITH HYPEROSMOTIC THERAPY (2013) (1)
- [Assessment of the severity of the condition of patients admitted to intensive care by measuring CRP]. (2015) (1)
- Recent developments in septic shock (1995) (1)
- Yearbook of Intensive Care and Emergency Medicine 2010 (2010) (1)
- Mechanisms of pulmonary edema: implications for plasma volume expansion (1992) (1)
- Pharmacological Studies in Hospitalized COVID-19 Patients in Belgium: We Could Do Better (2022) (1)
- What Have We Learned from the Surviving Sepsis Campaign (2011) (1)
- A.R.D.S. (1992) (1)
- HYPOALBUMINEMIA IN ACUTELY ILL PATIENTS. RISKS AND RESULTS OF TREATMENT: A META-ANALYSIS OF COHORT STUDIES AND CONTROLLED TRIALS: 521 (2002) (1)
- Does Albumin Administration Influence Outcome? Results of the SOAP Stud (2003) (1)
- Low hemoglobin and venous saturation levels are associated with poor neurological outcomes after cardiac arrest. (2020) (1)
- Comment on the paper “Hypophosphatemia after cardiothoracic surgery” (2004) (1)
- Organ donation after circulatory death: please do not waste time! (2021) (1)
- Do not (over) resuscitate. Authors' reply (2005) (1)
- Reply to Andrade and Pallin (2010) (1)
- 362: A NEW DOSE REGIMEN FOR CONTINUOUS INFUSION OF VANCOMYCIN TO RAPIDLY ACHIEVE TARGET CONCENTRATIONS (2012) (1)
- Our European study on blood transfusions: three quarters full or one quarter empty? (2008) (1)
- Alkaline Phosphatase Improves Kidney Function in Icu Patients With Sepsis-induced Acute Kidney Injury (2010) (1)
- Hemodynamic effects of Ketanserin, a new serotonine antagonist, in patients with acute respiratory failure after circulatory shock (1983) (1)
- Nitric oxide does not influence tissue oxygen extraction capabilities in low cardiac output. (1997) (1)
- Effects of vasoconstrictor tone on 02 extraction during isoflurane anaesthesia (1992) (1)
- 105: EVALUATION OF ENDOTHELIAL DAMAGE IN SEPSIS-RELATED ARDS USING CIRCULATING ENDOTHELIAL CELL COUNTS (2012) (1)
- Uncommon diseases in the ICU (2014) (1)
- Clinical applications of SDF videomicroscopy (2012) (1)
- Fever Control in Septic Shock: Beneficial or Harmful (2003) (1)
- The new Surviving Sepsis Campaign recommendations on glucose control: reply to Schultz et al. (2008) (1)
- Ethical issues in cardiac arrest and acute cardiac care: a European perspective (2018) (1)
- THE BENEFICIAL EFFECTS OF THERAPEUTIC HYPERCAPNIA IN A CLINICALLY RELEVANT MODEL OF SEPTIC SHOCK.: 100-T (2005) (1)
- Cardiac function in acute respiratory failure (1989) (1)
- The evidence-base and clinical trials in the ICU (2009) (1)
- Place of vasoactive agents in the treatment of acute circulatory failure. (1984) (1)
- Management of the critically ill patients with cirrhosis: A multidisciplinary perspective (vol 64, pg 717, 2016) (2016) (1)
- New developments in pulmonary artery catheterization (1986) (1)
- Serotonine antagonist administration in adult respiratory distress syndrome (1983) (1)
- The changing face of critical care: Task force on tropical diseases. (2017) (1)
- Surviving sepsis in developing countries (2008) (1)
- Bacterial etiology of community-acquired pneumonia in immunocompetent hospitalized patients and appropriateness of empirical treatment recommendations: an international point-prevalence study (2020) (1)
- Hemodynamic and Gasometric Implications of SvO2 Measurements (1985) (1)
- A313 Dobutamfne and Norepinephrine Treatment In Relation to Oxygen Delivery and Consumption in Endotoxin Shock (1990) (1)
- 973: Beta-lactams concentrations after lung transplantation (2013) (1)
- THE ICU DISCHARGE SCORE TO EVALUATE THE RISK OF READMISSION (2005) (1)
- 537: Microcirculatory alterations after resuscitated cardiac arrest (2013) (1)
- Tyrosine: a possible marker of severe intestinal injury during ischemia. (2009) (1)
- Nosocomial infections in the ICU (2004) (1)
- 1297: THE EFFECTS OF VASOPRESSIN AND NOREPINEPHRINE ON RENAL AUTOREGULATION IN EXPERIMENTAL SEPTIC SHOCK (2016) (1)
- Basis of treatment of myocardial failure. (1988) (1)
- New hope for sepsis (2001) (1)
- The Story of the Pulmonary Artery Catheter: Five Decades in Critical Care Medicine. (2023) (1)
- Severe sepsis and septic shock : are we making progress ? (1994) (1)
- Delivery-dependent oxygen consumption: what was the question? (1995) (1)
- Human Albumin in Critically Ill Patients (2005) (1)
- Acute Heart Failure (1989) (1)
- Obtaining pulmonary artery catheter data is too labor intense to be reliable (2009) (1)
- Human Cytokine response to cardiac operations: Prebypass factory (1996) (1)
- 1050: Gamma-globulin levels in patients with septic shock (2013) (1)
- Databases, Registries and Networks (2002) (1)
- The role of cardiovascular failure (1989) (1)
- Pathophysiology of pulmonary edema: role of colloid osmotic pressure (1992) (1)
- The source of cytokines during clinical cardiopulmonary bypass: The heart or the lung? (1996) (1)
- Relationship Between Oxygen Demand and Oxygen Supply in Severe Sepsis (1993) (1)
- Administration of dichloroacetate in septic shock decreases blood lactate levels but does not improve haemodynamics (1994) (1)
- Calculation of left ventricular stroke work (1993) (1)
- Sarcosinemia (2020) (1)
- Antibiotic resistance: understanding and responding to an emerging crisis (2011) (1)
- Epinephrine: what place in sepsis? (2008) (1)
- SIALIC ACID METABOLISM IN SEPSIS: 250 (2002) (1)
- Selective digestive decontamination and antibiotic resistance – Authors' reply (2012) (1)
- Newer therapies for septicemia (1992) (1)
- Organ failure in the intensive care unit. (2011) (1)
- Hemodynamic support of the critically ill patient (2008) (1)
- Vasopressin: useful or not? (2008) (1)
- EFFECTS OF ‘INJURY’ ON CRITICAL OXYGEN DELIVERY: A POTENTIAL HAEMODYNAMIC MECHANISM?: 16 (1994) (1)
- Tight glucose control: Sweet or sour? (2009) (1)
- Circulatory shock associated with magnesium depletion (2005) (1)
- Effects of infrequent turning on chest complications in critically ill patients (1997) (1)
- ScvO2 as a marker for resuscitation in intensive care (2008) (1)
- Physiology of VO2/DO2 (1997) (1)
- Cardiac Output Measurement in the Critically Ill: Invasive Versus Noninvasive Techniques (1991) (1)
- Trying to win the war against antibiotics resistance (2012) (1)
- IMPROVEMENT OF PaO2 BY CORRECTION OF METABOLIC ALKALOSIS (1982) (1)
- Intensive care and emergency medicine : 4th international symposium (1984) (1)
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- Editorial introductions. (2018) (0)
- Editorial introductions. (2020) (0)
- EPIDEMIOLOGY AND CLINICAL OUTCOMES: 446 (2004) (0)
- The continuing steroid debate. (2008) (0)
- Clinical Trials Review (2009) (0)
- Clinical trials report (2006) (0)
- ECMO takes the spotlight on Tuesday (0)
- Discussion Held 1 July, 1989: Afternoon (1990) (0)
- Clinical trials report (2008) (0)
- Combining the old with the new to improve therapeutics (2006) (0)
- New inotropic agents (1989) (0)
- About the Editor (1981) (0)
- Contents Vol. 38, 2006 (2006) (0)
- Editorial introductions. (2019) (0)
- Update 1989 (1989) (0)
- Sports shoe sole (1986) (0)
- Emerging paradigms in sepsis (2022) (0)
- Scheie syndrome (2020) (0)
- Traitement inutile "Futility" (2001) (0)
- Subject Index Vol. 38, 2006 (2006) (0)
- Discussion Held 1 July, 1989: Morning (1990) (0)
- Debate: Open or closed ICUs? (1999) (0)
- O-67 Challenges of eolc and following advance care plans in critical care medicine (2015) (0)
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