Jean Vance
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British-Canadian biochemist
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Molecular Biology
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Biochemistry
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Biology
Why Is Jean Vance Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jean Vance is a British-Canadian biochemist. She is known for her pioneering work on subcellular organelles and for her discovery of a connection between the endoplasmic reticulum and the mitochondrial membrane. She is a Professor of Medicine at the University of Alberta, Canada and a Fellow of the Royal Society of Canada.
Jean Vance's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biochemistry of Lipids, Lipoproteins and Membranes (2002) (1361)
- Growth and Perfection of Crystals. (1959) (1287)
- Phospholipid synthesis in a membrane fraction associated with mitochondria. (1990) (967)
- The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease. (2017) (602)
- Mechanisms of lipid-body formation. (1999) (580)
- MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond. (2014) (504)
- Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells. (2013) (452)
- Metabolism and functions of phosphatidylserine. (2005) (446)
- A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins. (1994) (420)
- Phospholipid Synthesis and Transport in Mammalian Cells (2015) (403)
- Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically related aminophospholipids. (2008) (346)
- Phospholipid biosynthesis in mammalian cells. (2004) (336)
- Phosphatidylserine Synthase-1 and -2 Are Localized to Mitochondria-associated Membranes* (2000) (316)
- Biochemistry of Lipids and Membranes (1985) (290)
- Phosphatidylcholine biosynthesis and lipoprotein metabolism. (2012) (282)
- Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases (2012) (274)
- Import of lipids into mitochondria. (1997) (262)
- Acyl-CoA Synthetase Isoforms 1, 4, and 5 Are Present in Different Subcellular Membranes in Rat Liver and Can Be Inhibited Independently* (2001) (255)
- Phosphatidylethanolamine Deficiency in Mammalian Mitochondria Impairs Oxidative Phosphorylation and Alters Mitochondrial Morphology* (2012) (217)
- Cholesterol homeostasis in neurons and glial cells. (2005) (216)
- Disruption of the Phosphatidylserine Decarboxylase Gene in Mice Causes Embryonic Lethality and Mitochondrial Defects* (2005) (215)
- Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase. A specific biochemical and cytological marker for a unique membrane fraction in rat liver. (1993) (209)
- The Role of Nogo and the Mitochondria–Endoplasmic Reticulum Unit in Pulmonary Hypertension (2011) (207)
- Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum. (1991) (204)
- Fatty acid desaturation and chain elongation in eukaryotes (2003) (193)
- Newly made phosphatidylserine and phosphatidylethanolamine are preferentially translocated between rat liver mitochondria and endoplasmic reticulum. (1991) (191)
- Role of Lipoproteins in the Delivery of Lipids to Axons during Axonal Regeneration* (1997) (181)
- Glial Lipoproteins Stimulate Axon Growth of Central Nervous System Neurons in Compartmented Cultures* (2004) (177)
- Apolipoprotein E-Containing Lipoproteins Protect Neurons from Apoptosis via a Signaling Pathway Involving Low-Density Lipoprotein Receptor-Related Protein-1 (2007) (160)
- Does rat liver Golgi have the capacity to synthesize phospholipids for lipoprotein secretion? (1988) (158)
- Formation and function of apolipoprotein E-containing lipoproteins in the nervous system. (2010) (155)
- Ero1α requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM) (2010) (154)
- Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann–Pick C1‐deficient neurons (2002) (152)
- Lipid imbalance in the neurological disorder, Niemann‐Pick C disease (2006) (147)
- Impaired ABCA1-dependent Lipid Efflux and Hypoalphalipoproteinemia in Human Niemann-Pick type C Disease* (2003) (144)
- The synthesis and transport of lipids for axonal growth and nerve regeneration. (2000) (138)
- Microsomal Triacylglycerol Transfer Protein Is Required for Lumenal Accretion of Triacylglycerol Not Associated with ApoB, as Well as for ApoB Lipidation* (2002) (138)
- Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin (2014) (136)
- Mechanisms and consequences of impaired lipid trafficking in Niemann-Pick type C1-deficient mammalian cells. (2009) (131)
- Expression of ABCG1, but Not ABCA1, Correlates with Cholesterol Release by Cerebellar Astroglia* (2006) (129)
- LACTB is a tumour suppressor that modulates lipid metabolism and cell state (2017) (121)
- Brefeldin A does not inhibit the movement of phosphatidylethanolamine from its sites for synthesis to the cell surface. (1991) (121)
- Molecular and cell biology of phosphatidylserine and phosphatidylethanolamine metabolism. (2003) (117)
- Uptake of Lipoproteins for Axonal Growth of Sympathetic Neurons* (2000) (116)
- Functional roles of lipids in membranes (2003) (115)
- Trafficking of Cholesterol from Cell Bodies to Distal Axons in Niemann Pick C1-deficient Neurons* (2003) (108)
- Defective cholesterol trafficking in Niemann‐Pick C‐deficient cells (2010) (106)
- Evidence that the Major Membrane Lipids, Except Cholesterol, Are Made in Axons of Cultured Rat Sympathetic Neurons (1994) (106)
- Phospholipid biosynthesis in eukaryotes (2008) (106)
- The eicosanoids : cyclooxygenase , lipoxygenase , and epoxygenase pathways (2003) (104)
- The role of phosphatidylcholine biosynthesis in the secretion of lipoproteins from hepatocytes. (1985) (101)
- Specific pools of phospholipids are used for lipoprotein secretion by cultured rat hepatocytes. (1986) (98)
- A Choline-deficient Diet in Mice Inhibits neither the CDP-choline Pathway for Phosphatidylcholine Synthesis in Hepatocytes nor Apolipoprotein B Secretion* (2004) (93)
- Assembly of rat hepatic very low density lipoproteins in the endoplasmic reticulum. (1993) (91)
- Lipid metabolism in plants (2003) (89)
- A mitochondrial membrane protein is required for translocation of phosphatidylserine from mitochondria-associated membranes to mitochondria. (1998) (88)
- Normalization of Cholesterol Homeostasis by 2-Hydroxypropyl-β-cyclodextrin in Neurons and Glia from Niemann-Pick C1 (NPC1)-deficient Mice* (2012) (87)
- Lipoproteins secreted by cultured rat hepatocytes contain the antioxidant 1-alk-1-enyl-2-acylglycerophosphoethanolamine. (1990) (84)
- Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice. (2009) (83)
- Eukaryotic lipid-biosynthetic enzymes: the same but not the same. (1998) (80)
- Elevation of Ceramide within Distal Neurites Inhibits Neurite Growth in Cultured Rat Sympathetic Neurons* (1997) (79)
- Defining the Importance of Phosphatidylserine Synthase 2 in Mice* (2002) (77)
- Lipid dynamics in neurons. (2006) (77)
- Defining the Importance of Phosphatidylserine Synthase-1 (PSS1) (2008) (72)
- Axonal synthesis of phosphatidylcholine is required for normal axonal growth in rat sympathetic neurons (1995) (70)
- Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice Published, JLR Papers in Press, October 24, 2007. (2008) (70)
- Gain-of-function mutations in the phosphatidylserine synthase 1 (PTDSS1) gene cause Lenz-Majewski syndrome (2013) (69)
- Lipoprotein assembly and secretion by hepatocytes. (1990) (68)
- Biochemistry.of.Lipids,.Lipoproteins.and.Membranes,.4th.edition (2002) (67)
- Lack of Phosphatidylethanolamine N-Methyltransferase Alters Plasma VLDL Phospholipids and Attenuates Atherosclerosis in Mice (2009) (66)
- Abnormalities in mitochondria-associated membranes and phospholipid biosynthetic enzymes in the mnd/mnd mouse model of neuronal ceroid lipofuscinosis. (1997) (64)
- Stimulation of apolipoprotein secretion in very-low-density and high-density lipoproteins from cultured rat hepatocytes by dexamethasone. (1990) (60)
- Hypersecretion of VLDL, but not HDL, by hepatocytes from the JCR:LA-corpulent rat. (1990) (59)
- Protection of Neurons from Apoptosis by Apolipoprotein E-containing Lipoproteins Does Not Require Lipoprotein Uptake and Involves Activation of Phospholipase Cγ1 and Inhibition of Calcineurin* (2009) (58)
- Function of the Niemann–Pick type C proteins and their bypass by cyclodextrin (2011) (57)
- Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann‐Pick type C1‐deficient mouse brains (2010) (53)
- Cloning and Expression of Mouse Liver Phosphatidylserine Synthase-1 cDNA (1998) (53)
- Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2. (1999) (52)
- Correction of Apolipoprotein A-I-mediated Lipid Efflux and High Density Lipoprotein Particle Formation in Human Niemann-Pick Type C Disease Fibroblasts* (2006) (52)
- The Niemann-Pick C1 protein in recycling endosomes of presynaptic nerve terminals Published, JLR Papers in Press, December 10, 2005. (2006) (49)
- Chapter 17 - Structure, assembly and secretion of lipoproteins (1996) (49)
- Lipid Homeostasis and Lipoprotein Secretion in Niemann-Pick C1-deficient Hepatocytes* (2007) (48)
- Movement of apolipoprotein B into the lumen of microsomes from hepatocytes is disrupted in membranes enriched in phosphatidylmonomethylethanolamine. (1993) (48)
- Sphingomyelin transport to the cell surface occurs independently of protein secretion in rat hepatocytes. (1993) (46)
- Development of a Rab9 transgenic mouse and its ability to increase the lifespan of a murine model of Niemann-Pick type C disease. (2009) (45)
- Historical perspective: phosphatidylserine and phosphatidylethanolamine from the 1800s to the present (2018) (45)
- Enhanced Expression and Activation of CTP:Phosphocholine Cytidylyltransferase β2 during Neurite Outgrowth* (2003) (44)
- Generation and function of astroglial lipoproteins from Niemann-Pick type C1-deficient mice. (2005) (44)
- Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity (2019) (43)
- Metabolic Insights into Phospholipid Function Using Gene-targeted Mice* (2005) (42)
- Biosynthesis of membrane lipids in rat axons. (1991) (41)
- Ceramide Inhibits Axonal Growth and Nerve Growth Factor Uptake without Compromising the Viability of Sympathetic Neurons* (2001) (40)
- Adipose tissue and lipid metabolism (39)
- Intracellular trafficking of phospholipids: import of phosphatidylserine into mitochondria. (1996) (39)
- Phospholipid homeostasis in phosphatidylserine synthase-2-deficient mice. (2006) (39)
- Phosphatidylcholine Biosynthesis via CTP:Phosphocholine Cytidylyltransferase β2 Facilitates Neurite Outgrowth and Branching* (2008) (38)
- Structure and Expression of the Murine Phosphatidylserine Synthase-1 Gene* (2001) (36)
- Alkylphosphocholines inhibit choline uptake and phosphatidylcholine biosynthesis in rat sympathetic neurons and impair axonal extension. (1995) (36)
- The use of newly synthesized phospholipids for assembly into secreted hepatic lipoproteins. (1989) (35)
- Evidence for an ethanolamine cycle: differential recycling of the ethanolamine moiety of phosphatidylethanolamine derived from phosphatidylserine and ethanolamine. (1995) (34)
- Fatty acid and phospholipid metabolism in prokaryotes (2003) (34)
- Lack of phosphatidylethanolamine N-methyltransferase alters hepatic phospholipid composition and induces endoplasmic reticulum stress. (2015) (33)
- Inter-organelle membrane contact sites: implications for lipid metabolism (2020) (33)
- Compartmentalization of phospholipids for lipoprotein assembly on the basis of molecular species and biosynthetic origin. (1988) (32)
- Transfer of cholesterol by the NPC team. (2010) (32)
- In Vitro Reconstitution of Assembly of Apolipoprotein B48-containing Lipoproteins* (1997) (31)
- Assembly and secretion of lipoproteins (2002) (31)
- PISD is a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes (2018) (30)
- Inhibition of Secretion of Truncated Apolipoproteins B by Monomethylethanolamine Is Independent of the Length of the Apolipoprotein (*) (1995) (30)
- Fatty acid synthesis in eukaryotes (2003) (29)
- Oxidation of fatty acids in eukaryotes (2003) (28)
- A Potential Neuroprotective Role of Apolipoprotein E-containing Lipoproteins through Low Density Lipoprotein Receptor-related Protein 1 in Normal Tension Glaucoma* (2012) (28)
- The biosynthesis of phosphatidylcholine by methylation of phosphatidylethanolamine derived from ethanolamine is not required for lipoprotein secretion by cultured rat hepatocytes. (1986) (28)
- Compartmentalization and differential labeling of phospholipids of rat liver subcellular membranes. (1988) (25)
- Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins. (2011) (25)
- APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease. (2015) (25)
- Secretion of VLDL, but not HDL, by rat hepatocytes is inhibited by the ethanolamine analogue N-monomethylethanolamine. (1991) (24)
- Neutral Triglyceride Lipase in Macrophages (1984) (23)
- Involvement of CTP:phosphocholine cytidylyltransferase-β2 in axonal phosphatidylcholine synthesis and branching of neurons. (2011) (22)
- The Vapor Pressure of Zinc between 150° and 350°C (1954) (22)
- Externalization of phosphatidylserine during apoptosis does not specifically require either isoform of phosphatidylserine synthase. (2004) (21)
- A deazaadenosine‐insensitive methylation of phosphatidylethanolamine is involved in lipoprotein secretion (1986) (21)
- Niemann-Pick Type C1 deficiency in microglia does not cause neuron death in vitro. (2011) (19)
- Novel Role for Matrix Metalloproteinase 9 in Modulation of Cholesterol Metabolism (2016) (18)
- Sphingolipids : metabolism and cell signaling (2017) (18)
- Compartmentalization of choline and acetylcholine metabolism in cultured sympathetic neurons. (2001) (18)
- The Vapor Pressure of Zinc in the Range 300°—360°C (1951) (17)
- Dynamics of lipoprotein transport in the human circulatory system (2003) (16)
- Role of axons in membrane phospholipid synthesis in rat sympathetic neurons (1995) (16)
- Lipoprotein Lipase in Cultured Pig Aortic Smooth Muscle Cells (1982) (15)
- Neuronal models for studying lipid metabolism and transport. (2005) (14)
- Translocational pausing of apolipoprotein B can be regulated by membrane lipid composition. (1998) (14)
- Colorimetric Determination of Strontium with Chloranilic Acid (1954) (11)
- Assembly and secretion of triacylglycerol-rich lipoproteins (2008) (11)
- Cloning and Expression of Mouse Liver Phosphatidylserine Synthase-1 cDNA OVEREXPRESSION IN RAT HEPATOMA CELLS INHIBITS THE CDP-ETHANOLAMINE PATHWAY FOR PHOSPHATIDYLETHANOLAMINE BIOSYNTHESIS* (1998) (11)
- Lipid modifications of proteins (2003) (11)
- The Solubility of Lead Chloride in Sodium Chloride, Perchloric Acid and Hydrochloric Acid Solutions1 (1953) (11)
- The assembly of lipids into lipoproteins during secretion (1990) (10)
- Adenovirus expressing an NPC1‐GFP fusion gene corrects neuronal and nonneuronal defects associated with Niemann pick type C disease (2005) (10)
- GRAVIMETRIC METHODS FOR ZINC AND ITS SEPARATION FROM CERTAIN ELEMENTS USE OF A RADIOISOTOPE IN EVALUATION OF ANALYTICAL PROCEDURES (1953) (10)
- Insufficient glucose supply is linked to hypothermia upon cold exposure in high-fat diet-fed mice lacking PEMT[S] (2015) (9)
- N-Myc and SP Regulate Phosphatidylserine Synthase-1 Expression in Brain and Glial Cells* (2010) (9)
- Cloning and expression of murine liver phosphatidylserine synthase ( PSS )-2 : differential regulation of phospholipid metabolism by PSS 1 and PSS 2 (1999) (8)
- Analytical Approaches for Investigating Apoptosis and Other Biochemical Events in Compartmented Cultures of Sympathetic Neurons (2002) (8)
- IDH1 regulates phospholipid metabolism in developing astrocytes (2014) (7)
- Membrane Lipid Biosynthesis (2010) (7)
- Lack of phosphatidylethanolamine N-methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle. (2016) (6)
- Reciprocal regulation of choline acetyltransferase and choline kinase in sympathetic neurons during cholinergic differentiation. (1995) (5)
- Monomethylethanolamine reduces plasma triacylglycerols and apolipoprotein B and increases apolipoprotein A-I rats without induction of fatty liver. (1996) (5)
- Significance of Fungus Growth in Analytical and Radiochemical Work with Strontium-containing Solutions1 (1953) (5)
- Methods for the study of lipid metabolism in neurons. (2004) (4)
- Protection of neurons from apoptosis by apolipoprotein E-containing lipoproteins (2010) (4)
- Synthesis and mass spectrometry of new compounds related to the tocopherols and plastoquinones (1971) (3)
- New comprehensive biochemistry, volume 31 biochemistry of lipids, lipoproteins and membranes11Reviewed by G. L. Squadrito, Biodynamics Institute, 711 Choppin Hall, Louisiana State University, Baton Rouge, LA 70803-1800, USA (1999) (3)
- The Influence of Hydrogen Ion Concentration, Solubility, Rate of Precipitation and Relative Supersaturation on the Crystal Growth of Strontium Sulfate (1952) (3)
- Comprar Biochemistry of Lipids, Lipoproteins and Membranes | J.E. Vance | 9780444532190 | Elsevier Science (2008) (3)
- A Rare Case of Cholecystoduodenal Fistula with Rapid Distal Gallstone Migration (2021) (3)
- THERMODYNAMIC FUNCTIONS FOR FLUORINE (1950) (2)
- Inflammation in the Niemann‐Pick type‐C brain (2007) (2)
- An unusual tocopherol isomer with an O-methyl group from Euglena gracilis☆ (1971) (1)
- Cellular itinerary of LDL cholesterol (2022) (1)
- SPECTROPHOTOMETRIC AND VISUAL TITRATIONS OF MILLIGRAM AMOUNTS OF STRONTIUM WITH EDTA. (1969) (1)
- Cyclodextrin normalizes cholesterol transport in Niemann-Pick C disease (2011) (1)
- Interpreting the effects of blocking PC biosynthesis. (1992) (1)
- Cellular lipid transport processes and their role in human disease. (2009) (1)
- Inter-organelle membrane contact sites: implications for lipid metabolism (2020) (0)
- Regulation of translocation of apolipoprotein B across the ER membrane by a ‘pause-transfer’ sequence and membrane lipid composition (1994) (0)
- Thermodynamics of Solids. (1962) (0)
- ANNUAL PROGRESS REPORT ON THE NATURE OF CRYSTAL GROWTH FROM SOLUTION (1952) (0)
- Essentials of Qualitative Analysis (1957) (0)
- Genetic reduction of mitochondrial phosphatidylethanolamine in mammalian cells impairs mitochondrial function (2010) (0)
- Inhibition of Neurite Growth by Ceramide in Rat Sympathetic Neurons (1998) (0)
- Reduced expression of CTP-phosphocholine cytidylyltrans-ferase-ß2 in PC12 cells and knock-out mice inhibits neurite branching (2008) (0)
- List of contributors**Authors’ names are followed by the starting page number(s) of their contribution(s). (2008) (0)
- Cholesterol Homeostasis in Niemann-Pick type C disease (2007) (0)
- ReviewInstant cities: Urbanization and the rise of San Francisco and Denver: Gunther Barth, (New York: Oxford University Press, Urban Life in America Series, 1975. Pp. xxv + 310. $11·95) (1978) (0)
- Metabolism and function of bile acids Lui (2003) (0)
- Advanced Analytical Chemistry (2012) (0)
- ( NPC 1 )-deficient Mice Neurons and Glia from Niemann-Pick C 1-cyclodextrin in β by 2-Hydroxypropyl-Normalization of Cholesterol Homeostasis Lipids : (2012) (0)
- Overview of lipoprotein secretion into the circulation (2003) (0)
- Lipid dynamics in neurons (2007) (0)
- Interorganelle Trafficking of Phosphatidylserine and Phosphatidylethanolamine (1992) (0)
- S013 Lipid Dynamics in Neurons (2005) (0)
- Short Communication Development of a Rab9 Transgenic Mouse and Its Ability to Increase the Lifespan of a Murine Model of Niemann-Pick Type C Disease (2008) (0)
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