Jeffery D. Molkentin | Academic Influence

Jeffery D. Molkentin's AcademicInfluence.com Rankings

Jeffery D. Molkentin

Biology

#3488

World Rank

#5329

Historical Rank

Cell Biology

#90

World Rank

#95

Historical Rank

Molecular Biology

#274

World Rank

#279

Historical Rank

Genetics

#298

World Rank

#351

Historical Rank

biology Degrees

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Biology

Jeffery D. Molkentin's Degrees

Bachelors Biology University of California, Berkeley
PhD Molecular Biology Stanford University

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Why Is Jeffery D. Molkentin Influential?

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According to Wikipedia, Jeffery Daniel Molkentin is an American molecular biologist. He is the director of Molecular Cardiovascular Biology for Cincinnati Children's hospital where he is also co-director of their Heart Institute. Molkentin holds a professorship at the University of Cincinnati's Department of Pediatrics.

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Jeffery D. Molkentin's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy (1998) (2645)
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death (2005) (2171)
Regulation of cardiac hypertrophy by intracellular signalling pathways (2006) (1843)
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. (1997) (1219)
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death (2007) (909)
The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6 (2000) (906)
Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins (1995) (864)
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease (2008) (820)
The MEK1–ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice (2000) (796)
Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury (2007) (792)
Calcineurin/NFAT Coupling Participates in Pathological, but not Physiological, Cardiac Hypertrophy (2004) (752)
Cytoplasmic signaling pathways that regulate cardiac hypertrophy. (2001) (732)
c-kit+ Cells Minimally Contribute Cardiomyocytes to the Heart (2014) (726)
Temporally Regulated and Tissue-Specific Gene Manipulations in the Adult and Embryonic Heart Using a Tamoxifen-Inducible Cre Protein (2001) (635)
Genetic lineage tracing defines myofibroblast origin and function in the injured heart (2016) (553)
Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues (2007) (528)
PKC-α regulates cardiac contractility and propensity toward heart failure (2004) (527)
Molecular pathways underlying cardiac remodeling during pathophysiological stimulation. (2010) (507)
Defining the regulatory networks for muscle development. (1996) (477)
Fibroblast-specific TGF-β-Smad2/3 signaling underlies cardiac fibrosis. (2017) (476)
Molecular basis of physiological heart growth: fundamental concepts and new players (2012) (463)
Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs. (2004) (457)
Differential Activation of Signal Transduction Pathways in Human Hearts With Hypertrophy Versus Advanced Heart Failure (2001) (453)
Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals (2012) (447)
Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors. (1996) (444)
Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. (2004) (442)
The Transforming Growth Factor-&bgr; Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury (2006) (439)
GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation (2006) (436)
Genetic Manipulation of Periostin Expression Reveals a Role in Cardiac Hypertrophy and Ventricular Remodeling (2007) (424)
Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability (2006) (405)
Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure. (2007) (402)
Signaling effectors underlying pathologic growth and remodeling of the heart. (2013) (401)
Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death. (2002) (395)
FoxO Transcription Factors Promote Autophagy in Cardiomyocytes* (2009) (392)
Animal models of heart failure: a scientific statement from the American Heart Association. (2012) (372)
STRESS signaling pathways that modulate cardiac myocyte apoptosis. (2005) (357)
Cardiomyocyte Regeneration: A Consensus Statement. (2017) (354)
Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart (2018) (349)
PKC-alpha regulates cardiac contractility and propensity toward heart failure. (2004) (347)
Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling. (2003) (344)
Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice. (2010) (337)
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death (337)
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy (2008) (333)
A Redox-Dependent Pathway for Regulating Class II HDACs and Cardiac Hypertrophy (2008) (332)
Redefining the identity of cardiac fibroblasts (2017) (329)
Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene (1994) (327)
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
Physiological and pathological roles of the mitochondrial permeability transition pore in the heart. (2015) (317)
Induced Deletion of the N-Cadherin Gene in the Heart Leads to Dissolution of the Intercalated Disc Structure (2005) (315)
A Calcineurin-NFATc3-Dependent Pathway Regulates Skeletal Muscle Differentiation and Slow Myosin Heavy-Chain Expression (2000) (313)
Periostin Is Required for Maturation and Extracellular Matrix Stabilization of Noncardiomyocyte Lineages of the Heart (2008) (310)
The Transcription Factors GATA4 and GATA6 Regulate Cardiomyocyte Hypertrophy in Vitro and in Vivo * (2001) (310)
An acute immune response underlies the benefit of cardiac stem cell therapy (2019) (310)
The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury. (2006) (298)
Conditional Dicer Gene Deletion in the Postnatal Myocardium Provokes Spontaneous Cardiac Remodeling (2008) (296)
A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. (2012) (291)
FoxO Transcription Factors Promote Cardiomyocyte Survival upon Induction of Oxidative Stress* (2010) (290)
Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes (2002) (284)
The Transcription Factor GATA4 Is Activated by Extracellular Signal-Regulated Kinase 1- and 2-Mediated Phosphorylation of Serine 105 in Cardiomyocytes (2001) (274)
Targeted Disruption of NFATc3, but Not NFATc4, Reveals an Intrinsic Defect in Calcineurin-Mediated Cardiac Hypertrophic Growth (2002) (270)
The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart. (2015) (268)
Myofibroblasts: trust your heart and let fate decide. (2014) (265)
Calcineurin‐dependent cardiomyopathy is activated by TRPC in the adult mouse heart (2006) (260)
Impaired cardiac hypertrophic response in Calcineurin Aβ-deficient mice (2002) (260)
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells (2011) (260)
Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses (2008) (256)
TRPC channels are necessary mediators of pathologic cardiac hypertrophy (2010) (256)
Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA. (2001) (255)
Targeted Inhibition of p38 Mitogen-activated Protein Kinase Antagonizes Cardiac Injury and Cell Death Following Ischemia-Reperfusion in Vivo* (2004) (252)
The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability (2017) (249)
Redefining the roles of p38 and JNK signaling in cardiac hypertrophy: dichotomy between cultured myocytes and animal models. (2003) (247)
Calcineurin Promotes Protein Kinase C and c-Jun NH2-terminal Kinase Activation in the Heart (2000) (247)
Calcineurin and beyond: cardiac hypertrophic signaling. (2000) (246)
Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo (2007) (240)
The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation. (2011) (236)
Cardiac-Specific Loss of N-Cadherin Leads to Alteration in Connexins With Conduction Slowing and Arrhythmogenesis (2005) (232)
Extracellular Signal-Regulated Kinases 1 and 2 Regulate the Balance Between Eccentric and Concentric Cardiac Growth (2011) (228)
TRPC Channels As Effectors of Cardiac Hypertrophy (2011) (224)
MEK1-ERK2 Signaling Pathway Protects Myocardium From Ischemic Injury In Vivo (2004) (223)
Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. (2007) (222)
An emerging consensus on cardiac regeneration (2014) (221)
A series of mutations in the D-MEF2 transcription factor reveal multiple functions in larval and adult myogenesis in Drosophila. (1995) (217)
Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice (2013) (215)
Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo (2001) (215)
Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore. (2013) (214)
Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. (1997) (212)
Genetic Deletion of Myostatin From the Heart Prevents Skeletal Muscle Atrophy in Heart Failure (2010) (204)
PKCα regulates the hypertrophic growth of cardiomyocytes through extracellular signal–regulated kinase1/2 (ERK1/2) (2002) (204)
Mechanisms of necroptosis in T cells (2011) (204)
Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis (2017) (200)
Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism (2009) (200)
Mutational analysis of the DNA binding, dimerization, and transcriptional activation domains of MEF2C (1996) (194)
c‐Jun N‐terminal kinases (JNK) antagonize cardiac growth through cross‐talk with calcineurin–NFAT signaling (2003) (193)
Genetic Loss of Calcineurin Blocks Mechanical Overload-induced Skeletal Muscle Fiber Type Switching but Not Hypertrophy* (2004) (191)
Myocyte Enhancer Factors 2A and 2C Induce Dilated Cardiomyopathy in Transgenic Mice* (2006) (189)
Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis. (2008) (189)
Re-employment of developmental transcription factors in adult heart disease. (2007) (185)
A threshold of GATA4 and GATA6 expression is required for cardiovascular development. (2006) (183)
The Transcription Factors GATA4 and dHAND Physically Interact to Synergistically Activate Cardiac Gene Expression through a p300-dependent Mechanism* (2002) (178)
Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. (2011) (177)
A Thrombospondin-Dependent Pathway for a Protective ER Stress Response (2012) (175)
A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy (2016) (172)
The Dual-Specificity Phosphatase MKP-1 Limits the Cardiac Hypertrophic Response In Vitro and In Vivo (2001) (170)
The IP3 Receptor Regulates Cardiac Hypertrophy in Response to Select Stimuli (2010) (170)
PKCalpha regulates platelet granule secretion and thrombus formation in mice. (2009) (168)
Defective T cell development and function in calcineurin Aβ-deficient mice (2002) (167)
Calcineurin and cardiac hypertrophy: Where have we been? Where are we going? (2002) (167)
Temporally Controlled Onset of Dilated Cardiomyopathy Through Disruption of the SRF Gene in Adult Heart (2005) (167)
Multiple Roles for the MyoD Basic Region in Transmission of Transcriptional Activation Signals and Interaction with MEF2 (1998) (164)
Renaming the DSCR1 / Adapt78 gene family as RCAN: regulators of calcineurin (2007) (163)
DUSP6 (MKP3) Null Mice Show Enhanced ERK1/2 Phosphorylation at Baseline and Increased Myocyte Proliferation in the Heart Affecting Disease Susceptibility* (2008) (163)
The mitochondrial permeability transition pore in motor neurons: Involvement in the pathobiology of ALS mice (2009) (161)
Direct and Indirect Interactions between Calcineurin-NFAT and MEK1-Extracellular Signal-Regulated Kinase 1/2 Signaling Pathways Regulate Cardiac Gene Expression and Cellular Growth (2005) (161)
Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc. (2005) (159)
The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila. (1999) (156)
Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP (2015) (154)
Identification of a Cooperative Mechanism Involving Interleukin-13 and Eotaxin-2 in Experimental Allergic Lung Inflammation* (2005) (154)
Altered Skeletal Muscle Phenotypes in Calcineurin Aα and Aβ Gene-Targeted Mice (2003) (150)
Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells. (2009) (150)
Calcineurin and human heart failure (1999) (149)
Abnormalities of the Genitourinary Tract in Female Mice Lacking GATA5 (2000) (145)
Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice. (2012) (145)
Extracellular Signal-Regulated Kinase 2 Interacts with and Is Negatively Regulated by the LIM-Only Protein FHL2 in Cardiomyocytes (2004) (143)
Activated Notch Inhibits Myogenic Activity of the MADS-Box Transcription Factor Myocyte Enhancer Factor 2C (1999) (143)
CaMKII Negatively Regulates Calcineurin–NFAT Signaling in Cardiac Myocytes (2009) (139)
Interaction Between NF&kgr;B and NFAT Coordinates Cardiac Hypertrophy and Pathological Remodeling (2012) (139)
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene. (2009) (138)
Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle (2004) (137)
Requirement of Nuclear Factor of Activated T-cells in Calcineurin-mediated Cardiomyocyte Hypertrophy* (2002) (136)
Genetic Inhibition or Activation of JNK1/2 Protects the Myocardium from Ischemia-Reperfusion-induced Cell Death in Vivo* (2005) (135)
Increased Coupled Gating of L-Type Ca2+ Channels During Hypertension and Timothy Syndrome (2010) (135)
MEF2B is a potent transactivator expressed in early myogenic lineages (1996) (135)
Activation of NFATc3 Down-regulates the β1 Subunit of Large Conductance, Calcium-activated K+ Channels in Arterial Smooth Muscle and Contributes to Hypertension* (2007) (134)
Unrestrained erythroblast development in Nix−/− mice reveals a mechanism for apoptotic modulation of erythropoiesis (2007) (133)
Prevention of cardiac hypertrophy by calcineurin inhibition: hope or hype? (1999) (133)
Glycogen Synthase Kinase-3β Regulates Growth, Calcium Homeostasis, and Diastolic Function in the Heart* (2004) (133)
Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death. (2008) (133)
Protein Kinase Cα, but Not PKCβ or PKCγ, Regulates Contractility and Heart Failure Susceptibility: Implications for Ruboxistaurin as a Novel Therapeutic Approach (2009) (132)
Pharmacological- and Gene Therapy–Based Inhibition of Protein Kinase Cα/β Enhances Cardiac Contractility and Attenuates Heart Failure (2006) (132)
Preexisting endothelial cells mediate cardiac neovascularization after injury (2017) (131)
NFATc3 and NFATc4 Are Required for Cardiac Development and Mitochondrial Function (2003) (130)
Inhibiting Fibronectin Attenuates Fibrosis and Improves Cardiac Function in a Model of Heart Failure (2018) (129)
Genetic deletion of the mitochondrial phosphate carrier desensitizes the mitochondrial permeability transition pore and causes cardiomyopathy (2014) (129)
Periostin as a Heterofunctional Regulator of Cardiac Development and Disease (2008) (128)
A Critical Function for Ser-282 in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function (2011) (127)
Myocyte-specific enhancer-binding factor (MEF-2) regulates alpha-cardiac myosin heavy chain gene expression in vitro and in vivo. (1993) (127)
Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart. (2000) (127)
Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. (2006) (127)
Regulation of MEF2 by p38 MAPK and its implication in cardiomyocyte biology. (2000) (126)
Estrogen Attenuates Left Ventricular and Cardiomyocyte Hypertrophy by an Estrogen Receptor–Dependent Pathway That Increases Calcineurin Degradation (2009) (123)
Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. (2010) (123)
Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD (2018) (123)
Mechanisms Underlying Heterogeneous Ca2+ Sparklet Activity in Arterial Smooth Muscle (2006) (122)
Cross-regulation of Novel Protein Kinase C (PKC) Isoform Function in Cardiomyocytes (2003) (121)
Extracellular signal‐regulated kinase 1/2 (ERK1/2) signaling in cardiac hypertrophy (2010) (121)
MEKK1 Transduces Activin Signals in Keratinocytes To Induce Actin Stress Fiber Formation and Migration (2005) (117)
Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome. (2007) (117)
Interaction between TAK1–TAB1–TAB2 and RCAN1–calcineurin defines a signalling nodal control point (2009) (117)
Calcineurin and hypertrophic heart disease: novel insights and remaining questions. (2002) (116)
Manipulating Cardiac Contractility in Heart Failure: Data From Mice and Men (2004) (116)
Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease. (2013) (115)
Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-β pathway (2012) (115)
A Caveolae-Targeted L-Type Ca2+ Channel Antagonist Inhibits Hypertrophic Signaling Without Reducing Cardiac Contractility (2012) (113)
Blockade of Hsp20 Phosphorylation Exacerbates Cardiac Ischemia/Reperfusion Injury by Suppressed Autophagy and Increased Cell Death (2009) (113)
The β-Catenin/T-Cell Factor/Lymphocyte Enhancer Factor Signaling Pathway Is Required for Normal and Stress-Induced Cardiac Hypertrophy (2006) (113)
Phosphorylation of the MADS-Box Transcription Factor MEF2C Enhances Its DNA Binding Activity* (1996) (113)
Regulated necrotic cell death: the passive aggressive side of Bax and Bak. (2015) (111)
With great power comes great responsibility: using mouse genetics to study cardiac hypertrophy and failure. (2009) (108)
Dichotomy of Ca2+ in the heart: contraction versus intracellular signaling. (2006) (108)
Genetic Manipulation of Periostin Expression in the Heart Does Not Affect Myocyte Content, Cell Cycle Activity, or Cardiac Repair (2008) (107)
Functional Divergence of Platelet Protein Kinase C (PKC) Isoforms in Thrombus Formation on Collagen* (2010) (106)
Proteasome functional insufficiency activates the calcineurin-NFAT pathway in cardiomyocytes and promotes maladaptive remodelling of stressed mouse hearts. (2010) (106)
The Transcription Factor GATA-6 Regulates Pathological Cardiac Hypertrophy (2010) (104)
Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy. (2011) (104)
Identifying the components of the elusive mitochondrial permeability transition pore (2014) (103)
Myostatin from the heart: local and systemic actions in cardiac failure and muscle wasting. (2011) (102)
Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy. (2006) (101)
The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension (2008) (101)
The bovine mannose 6-phosphate/insulin-like growth factor II receptor. The role of arginine residues in mannose 6-phosphate binding. (1993) (101)
The DnaJ-Related Factor Mrj Interacts with Nuclear Factor of Activated T Cells c3 and Mediates Transcriptional Repression through Class II Histone Deacetylase Recruitment (2005) (100)
Lost in Transgenesis: A User's Guide for Genetically Manipulating the Mouse in Cardiac Research (2012) (100)
Calcineurin and NFAT4 Induce Chondrogenesis* (2002) (100)
Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo (2011) (99)
Calcineurin Enhances MAPK Phosphatase-1 Expression and p38 MAPK Inactivation in Cardiac Myocytes* (2001) (99)
Does Contractile Ca2+ Control Calcineurin-NFAT Signaling and Pathological Hypertrophy in Cardiac Myocytes? (2008) (99)
The Role of Calcium/Calmodulin-Activated Calcineurin in Rapid and Slow Endocytosis at Central Synapses (2010) (97)
Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure. (2006) (96)
Defective T cell development and function in calcineurin A beta -deficient mice. (2002) (95)
Inducible Cardiac-Restricted Expression of Enteroviral Protease 2A Is Sufficient to Induce Dilated Cardiomyopathy (2006) (95)
Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia. (2015) (95)
Deletion of cytosolic phospholipase A2 promotes striated muscle growth (2003) (95)
Transient Receptor Potential Channels Contribute to Pathological Structural and Functional Remodeling After Myocardial Infarction (2014) (95)
Genetic manipulation of the cardiac mitochondrial phosphate carrier does not affect permeability transition. (2014) (94)
Direct Interaction and Reciprocal Regulation between ASK1 and Calcineurin-NFAT Control Cardiomyocyte Death and Growth (2006) (94)
Novel blocker of NFAT activation inhibits IL-6 production in human myometrial arteries and reduces vascular smooth muscle cell proliferation. (2007) (93)
Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted mice. (2003) (92)
Calcium sparklets regulate local and global calcium in murine arterial smooth muscle (2007) (92)
High Glucose Activates Nuclear Factor of Activated T Cells in Native Vascular Smooth Muscle (2006) (91)
Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism. (2010) (91)
Placental Growth Factor Regulates Cardiac Adaptation and Hypertrophy Through a Paracrine Mechanism (2011) (91)
TGFβ‐mediated BIM expression and apoptosis are regulated through SMAD3‐dependent expression of the MAPK phosphatase MKP2 (2008) (91)
CIB1 is a Regulator of Pathological Cardiac Hypertrophy (2010) (90)
Calcineurin transgenic mice have mitochondrial dysfunction and elevated superoxide production. (2003) (90)
Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling. (2012) (90)
A murine model of inducible, cardiac-specific deletion of STAT3: its use to determine the role of STAT3 in the upregulation of cardioprotective proteins by ischemic preconditioning. (2011) (89)
alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice. (2009) (89)
Cardiac Myosin Binding Protein-C Phosphorylation in a &bgr;-Myosin Heavy Chain Background (2009) (88)
STIM1 elevation in the heart results in aberrant Ca²⁺ handling and cardiomyopathy. (2015) (88)
Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome (2008) (87)
Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells. (2010) (87)
Temporal activation of c‐Jun N‐terminal kinase in adult transgenic heart via cre‐loxP‐mediated DNA recombination (2003) (87)
GATA4: a novel transcriptional regulator of cardiac hypertrophy? (1997) (86)
RhoA protects the mouse heart against ischemia/reperfusion injury. (2011) (86)
The transcription factors GATA 4 and GATA 6 regulate cardiomyocyte hypertrophy in vitro and in vivo (2001) (84)
Mutual antagonism between IP3RII and miRNA-133a regulates calcium signals and cardiac hypertrophy (2012) (83)
Genetic evidence in the mouse solidifies the calcium hypothesis of myofiber death in muscular dystrophy (2015) (83)
Calcineurin A &bgr; Gene Targeting Predisposes the Myocardium to Acute Ischemia-Induced Apoptosis and Dysfunction (2004) (83)
Unrestrained p38 MAPK Activation in Dusp1/4 Double-Null Mice Induces Cardiomyopathy (2013) (81)
Plasma membrane Ca2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents. (2009) (81)
Reduction of Ito Causes Hypertrophy in Neonatal Rat Ventricular Myocytes (2002) (80)
Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis. (2002) (80)
Regulation of cardiac hypertrophy and remodeling through the dual-specificity MAPK phosphatases (DUSPs). (2016) (80)
A friend within the heart: natriuretic peptide receptor signaling. (2003) (80)
Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. (2009) (79)
ASK1 Regulates Cardiomyocyte Death but Not Hypertrophy in Transgenic Mice (2009) (78)
Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death (2015) (77)
Bile Acids Induce Pancreatic Acinar Cell Injury and Pancreatitis by Activating Calcineurin* (2012) (77)
DSCR1 gene expression is dependent on NFATc1 during cardiac valve formation and colocalizes with anomalous organ development in trisomy 16 mice. (2004) (77)
Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle. (2014) (77)
CONTRIBUTION OF MKP-1 REGULATION OF p38 TO ENDOTOXIN TOLERANCE (2005) (76)
Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species (2011) (76)
Calreticulin signals upstream of calcineurin and MEF2C in a critical Ca2+-dependent signaling cascade (2005) (75)
Modulation of chromatin position and gene expression by HDAC4 interaction with nucleoporins (2011) (75)
Activation of GATA-4 by Serotonin in Pulmonary Artery Smooth Muscle Cells* (2003) (75)
Cardiomyocyte-Specific Transforming Growth Factor &bgr; Suppression Blocks Neutrophil Infiltration, Augments Multiple Cytoprotective Cascades, and Reduces Early Mortality After Myocardial Infarction (2014) (74)
Ca2+ Influx Through T- and L-Type Ca2+ Channels Have Different Effects on Myocyte Contractility and Induce Unique Cardiac Phenotypes (2008) (73)
Individual Cardiac Mitochondria Undergo Rare Transient Permeability Transition Pore Openings. (2016) (73)
Genetic Analysis of Connective Tissue Growth Factor as an Effector of Transforming Growth Factor β Signaling and Cardiac Remodeling (2015) (72)
TOX Provides a Link Between Calcineurin Activation and CD8 Lineage Commitment (2004) (72)
Inhibition of Calcineurin and Sarcolemmal Ca2+ Influx Protects Cardiac Morphology and Ventricular Function in Kv4.2N Transgenic Mice (2002) (71)
Cardiac Hypertrophy and Reduced Contractility in Hearts Deficient in the Titin Kinase Region (2007) (70)
Cdc42 is an antihypertrophic molecular switch in the mouse heart. (2009) (70)
Insulin inhibits PDGF-directed VSMC migration via NO/ cGMP increase of MKP-1 and its inactivation of MAPKs. (2002) (70)
Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse hearts (2010) (70)
Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure. (2002) (69)
Divergent signaling pathways converge on GATA4 to regulate cardiac hypertrophic gene expression. (2002) (68)
Genetic Lineage Tracing of Sca-1+ Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart (2018) (68)
Alpha-myosin heavy chain gene regulation: delineation and characterization of the cardiac muscle-specific enhancer and muscle-specific promoter. (1996) (67)
Transforming Growth Factor &bgr;–Activated Kinase 1 Signaling Pathway Critically Regulates Myocardial Survival and Remodeling (2014) (67)
Calcineurin Links Mitochondrial Elongation with Energy Metabolism. (2015) (66)
The beta-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy. (2006) (66)
Overexpression of calcineurin in mouse causes sudden cardiac death associated with decreased density of K+ channels. (2003) (65)
An M-CAT binding factor and an RSRF-related A-rich binding factor positively regulate expression of the alpha-cardiac myosin heavy-chain gene in vivo (1994) (65)
Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak (2017) (64)
RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis (2014) (63)
Apoptotic cell death (2010) (63)
Unraveling the secrets of a double life: contractile versus signaling Ca2+ in a cardiac myocyte. (2012) (62)
Calcineurin, mitochondrial membrane potential, and cardiomyocyte apoptosis. (2001) (61)
The Elusive Progenitor Cell in Cardiac Regeneration: Slip Slidin’ Away (2017) (61)
Inducible and myocyte-specific inhibition of PKCalpha enhances cardiac contractility and protects against infarction-induced heart failure. (2007) (59)
MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response (2015) (59)
Genetic manipulation of dysferlin expression in skeletal muscle: novel insights into muscular dystrophy. (2009) (58)
Conditional Transgenic Expression of Fibroblast Growth Factor 9 in the Adult Mouse Heart Reduces Heart Failure Mortality After Myocardial Infarction (2011) (58)
Is nuclear factor kappaB an attractive therapeutic target for treating cardiac hypertrophy? (2003) (58)
Enhanced Ca²⁺ influx from STIM1-Orai1 induces muscle pathology in mouse models of muscular dystrophy. (2014) (57)
Moderate Calcium Channel Dysfunction in Adult Mice with Inducible Cardiomyocyte-specific Excision of the cacnb2 Gene* (2011) (57)
Inhibition of PKC&agr;/&bgr; With Ruboxistaurin Antagonizes Heart Failure in Pigs After Myocardial Infarction Injury (2011) (56)
Protein kinase Cα as a heart failure therapeutic target. (2011) (55)
Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species via O-linked GlcNAcylation and CaMKII Activation in Mouse Ventricular Myocytes (2020) (55)
Apoptotic cell death “Nixed” by an ER–mitochondrial necrotic pathway (2010) (53)
A mouse model of familial hypertrophic cardiomyopathy caused by a α-tropomyosin mutation (2003) (53)
Exposure to Radiocontrast Agents Induces Pancreatic Inflammation by Activation of Nuclear Factor-κB, Calcium Signaling, and Calcineurin. (2015) (53)
DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling. (2016) (53)
Sarcolipin overexpression improves muscle energetics and reduces fatigue. (2015) (53)
Overexpression of the Na+/K+ ATPase &agr;2 But Not &agr;1 Isoform Attenuates Pathological Cardiac Hypertrophy and Remodeling (2014) (53)
PDK1 coordinates survival pathways and β-adrenergic response in the heart (2009) (51)
Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK–NRF2 pathway (2016) (50)
Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice (2010) (50)
Deletion of Periostin Protects Against Atherosclerosis in Mice by Altering Inflammation and Extracellular Matrix Remodeling (2016) (50)
The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle. (2018) (50)
Phosphodiesterase 5 inhibition blocks pressure overload-induced cardiac hypertrophy independent of the calcineurin pathway. (2008) (49)
SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models. (2015) (49)
Calcineurin Increases Cardiac Transient Outward K+ Currents via Transcriptional Up-regulation of Kv4.2 Channel Subunits* (2006) (48)
Thioredoxin 1 Is Essential for Sodium Sulfide–Mediated Cardioprotection in the Setting of Heart Failure (2013) (48)
Calcineurin protects the heart in a murine model of dilated cardiomyopathy. (2010) (48)
Are resident c-Kit+ cardiac stem cells really all that are needed to mend a broken heart? (2013) (48)
Heart-specific Deletion of CnB1 Reveals Multiple Mechanisms Whereby Calcineurin Regulates Cardiac Growth and Function*♦ (2009) (47)
TEAD-1 Overexpression in the Mouse Heart Promotes an Age-dependent Heart Dysfunction* (2010) (47)
Reduction of I(to) causes hypertrophy in neonatal rat ventricular myocytes. (2002) (47)
Calcineurin regulates NFAT-dependent iNOS expression and protection of cardiomyocytes: co-operation with Src tyrosine kinase. (2006) (46)
Regulation of Calcineurin through Transcriptional Induction of the calcineurin Aβ Promoter In Vitro and In Vivo (2005) (46)
Acute lipoprotein lipase deletion in adult mice leads to dyslipidemia and cardiac dysfunction. (2006) (46)
Increasing Cardiac Contractility After Myocardial Infarction Exacerbates Cardiac Injury and Pump Dysfunction (2009) (46)
Sumo E2 Enzyme UBC9 Is Required for Efficient Protein Quality Control in Cardiomyocytes (2014) (46)
Myofiber-specific inhibition of TGFβ signaling protects skeletal muscle from injury and dystrophic disease in mice. (2014) (45)
Re-evaluating sarcoplasmic reticulum function in heart failure (2000) (45)
P38α MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism. (2014) (45)
Analysis of the transcriptional activity of endogenous NFAT5 in primary cells using transgenic NFAT-luciferase reporter mice (2008) (44)
Pharmacological and Activated Fibroblast Targeting of Gβγ-GRK2 After Myocardial Ischemia Attenuates Heart Failure Progression. (2017) (44)
Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations. (2015) (44)
Retinoic acid inhibits cardiac neural crest migration by blocking c-Jun N-terminal kinase activation. (2001) (43)
Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart (2019) (43)
MEF2B Is a Component of a Smooth Muscle-specific Complex That Binds an A/T-rich Element Important for Smooth Muscle Myosin Heavy Chain Gene Expression* (1998) (42)
The protein phosphatase calcineurin determines basal parathyroid hormone gene expression. (2005) (42)
Most of the Dust Has Settled: cKit+ Progenitor Cells Are an Irrelevant Source of Cardiac Myocytes In Vivo. (2016) (42)
Detection of 14 HLA-DQB1 alleles by oligotyping. (1991) (42)
Parsing Good Versus Bad Signaling Pathways in the Heart: Role of Calcineurin–Nuclear Factor of Activated T-Cells (2013) (41)
Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion. (2005) (41)
Cholecystokinin activates pancreatic calcineurin-NFAT signaling in vitro and in vivo. (2008) (40)
New Myocyte Formation in the Adult Heart: Endogenous Sources and Therapeutic Implications (2018) (40)
The Presence of Lys27 Instead of Asn27 in Human Phospholamban Promotes Sarcoplasmic Reticulum Ca2+-ATPase Superinhibition and Cardiac Remodeling (2006) (40)
Inositol 1,4,5-trisphosphate-mediated sarcoplasmic reticulum-mitochondrial crosstalk influences adenosine triphosphate production via mitochondrial Ca2+ uptake through the mitochondrial ryanodine receptor in cardiac myocytes. (2016) (39)
Cardiac function and electrical remodeling of the calcineurin-overexpressed transgenic mouse. (2002) (39)
Genetic Disruption of Calcineurin Improves Skeletal Muscle Pathology and Cardiac Disease in a Mouse Model of Limb-Girdle Muscular Dystrophy* (2007) (39)
Time-dependent systolic and diastolic function in mice overexpressing calcineurin. (2003) (38)
Repression of Cyclin D1 Expression Is Necessary for the Maintenance of Cell Cycle Exit in Adult Mammalian Cardiomyocytes* (2014) (38)
ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity (2019) (37)
Requirement of transcription factor NFAT in developing atrial myocardium (2003) (37)
Enhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity. (2010) (36)
GATA6 Promotes Angiogenic Function and Survival in Endothelial Cells by Suppression of Autocrine Transforming Growth Factor β/Activin Receptor-like Kinase 5 Signaling* (2010) (36)
Adenine nucleotide translocase-1 induces cardiomyocyte death through upregulation of the pro-apoptotic protein Bax. (2009) (36)
Targeting latent TGFβ release in muscular dystrophy (2014) (35)
Thrombospondin expression in myofibers stabilizes muscle membranes (2016) (35)
Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation (2020) (34)
Expression of the alpha-myosin heavy chain gene in the heart is regulated in part by an E-box-dependent mechanism. (1993) (34)
Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ (2016) (34)
Ca2+-dependent Dephosphorylation of Kinesin Heavy Chain on β-Granules in Pancreatic β-Cells (2002) (34)
Elevated Ca 2 (cid:1) sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells (2010) (34)
Isoform- and tissue-specific regulation of the Ca(2+)-sensitive transcription factor NFAT in cardiac myocytes and heart failure. (2010) (33)
Na+ Dysregulation Coupled with Ca2+ Entry through NCX1 Promotes Muscular Dystrophy in Mice (2014) (33)
Parsing the Roles of the Transcription Factors GATA-4 and GATA-6 in the Adult Cardiac Hypertrophic Response (2013) (32)
Is p53 the long-sought molecular trigger for cyclophilin D-regulated mitochondrial permeability transition pore formation and necrosis? (2012) (32)
Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability (2019) (32)
Cardiac Fibrosis in Proteotoxic Cardiac Disease is Dependent Upon Myofibroblast TGF‐β Signaling (2018) (32)
Phosphorylation of Protein Phosphatase Inhibitor-1 by Protein Kinase C* (2006) (32)
Excess SMAD signaling contributes to heart and muscle dysfunction in muscular dystrophy. (2014) (31)
Evidence for Minimal Cardiogenic Potential of Stem Cell Antigen 1–Positive Cells in the Adult Mouse Heart (2018) (30)
Pharmacological and genetic inhibition of calcineurin protects against carbachol-induced pathological zymogen activation and acinar cell injury. (2012) (30)
Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy (2021) (30)
Rcan1 negatively regulates FcεRI-mediated signaling and mast cell function (2009) (30)
A 20/20 view of ANT function in mitochondrial biology and necrotic cell death. (2020) (29)
Requirement of the calcineurin subunit gene canB2 for indirect flight muscle formation in Drosophila (2003) (29)
Calcineurin Abeta is central to the expression of the renal type II Na/Pi co-transporter gene and to the regulation of renal phosphate transport. (2004) (29)
Letter by Molkentin Regarding Article, “The Absence of Evidence Is Not Evidence of Absence: The Pitfalls of Cre Knock-Ins in the c-Kit Locus” (2014) (29)
TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury (2017) (29)
Gata4-Dependent Differentiation of c-Kit+–Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart (2018) (29)
Developing small molecules to inhibit kinases unkind to the heart: p38 MAPK as a case in point. (2010) (28)
BEX1 is an RNA-dependent mediator of cardiomyopathy (2017) (27)
A mouse model of familial hypertrophic cardiomyopathy caused by a alpha-tropomyosin mutation. (2003) (27)
Undeniable Evidence That the Adult Mammalian Heart Lacks an Endogenous Regenerative Stem Cell (2018) (25)
Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart (2019) (25)
Persistent increases in Ca2+ influx through Cav1.2 shortens action potential and causes Ca2+ overload-induced afterdepolarizations and arrhythmias (2015) (25)
The Transforming Growth Factor- (cid:1) Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury (2006) (25)
A TAK1 Signaling Pathway Critically Regulates Myocardial Survival and Remodeling (2014) (24)
A novel class of cardioprotective small-molecule PTP inhibitors. (2019) (24)
Genetic overexpression of Serpina3n attenuates muscular dystrophy in mice. (2016) (24)
Tropomyosin Dephosphorylation Results in Compensated Cardiac Hypertrophy* (2012) (24)
Postnatal Ablation of Foxm1 from Cardiomyocytes Causes Late Onset Cardiac Hypertrophy and Fibrosis without Exacerbating Pressure Overload-Induced Cardiac Remodeling (2012) (24)
Genetic inhibition of calcineurin induces diastolic dysfunction in mice with chronic pressure overload. (2009) (23)
Dissection of Thrombospondin-4 Domains Involved in Intracellular Adaptive Endoplasmic Reticulum Stress-Responsive Signaling (2015) (23)
Novel and nondetected human signaling protein polymorphisms. (2002) (23)
MCUb Induction Protects the Heart From Postischemic Remodeling (2020) (23)
Developmental vascular regression is regulated by a Wnt/β-catenin, MYC and CDKN1A pathway that controls cell proliferation and cell death (2018) (23)
Placental growth factor as a protective paracrine effector in the heart. (2011) (22)
The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension (2019) (22)
Abstract 3: Interaction Between NFκB and NFAT Coordinates Cardiac Hypertrophy and Pathological Remodeling (2011) (21)
Caveolae-localized L-type Ca2+ channels do not contribute to function or hypertrophic signalling in the mouse heart (2017) (21)
Myofibroblast-Specific TGF&bgr; Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy (2018) (20)
Requirement of Calcineurin Aβ for the Survival of Naive T Cells1 (2008) (20)
metabolic flexibility, and propensity for heart failure in mice (2010) (19)
TAK1 Regulates Myocardial Response to Pathological Stress via NFAT, NFκB, and Bnip3 Pathways (2015) (19)
Knockout of cyclophilin D in Ppif⁻/⁻ mice increases stability of brain mitochondria against Ca²⁺ stress. (2015) (19)
Calcineurin A-β is required for hypertrophy but not matrix expansion in the diabetic kidney (2009) (19)
Constitutively active MEK1 rescues cardiac dysfunction caused by overexpressed GSK-3α during aging and hemodynamic pressure overload. (2012) (19)
A specialized population of Periostin-expressing cardiac fibroblasts contributes to postnatal cardiomyocyte maturation and innervation (2020) (19)
Cardiac-specific deficiency of the mitochondrial calcium uniporter augments fatty acid oxidation and functional reserve. (2019) (19)
Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. (2011) (18)
Negative regulation of cyclin-dependent kinase 5 targets by protein kinase C. (2008) (17)
Protein kinase C alpha enhances sodium-calcium exchange during store-operated calcium entry in mouse platelets. (2010) (17)
Nuclear calcineurin is a sensor for detecting Ca2+ release from the nuclear envelope via IP3R (2018) (17)
Cysteine 202 of Cyclophilin D is a site of multiple post-translational modifications and plays a role in cardioprotection. (2019) (17)
Ablation of Calcineurin Aβ Reveals Hyperlipidemia and Signaling Cross-talks with Phosphodiesterases* (2012) (17)
An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels (2017) (15)
Defective Flux of Thrombospondin-4 through the Secretory Pathway Impairs Cardiomyocyte Membrane Stability and Causes Cardiomyopathy (2018) (15)
Cathepsin S Contributes to the Pathogenesis of Muscular Dystrophy in Mice* (2016) (15)
Requirement of calcineurin a beta for the survival of naive T cells. (2008) (15)
Increasing T‐type calcium channel activity by β‐adrenergic stimulation contributes to β‐adrenergic regulation of heart rates (2017) (15)
Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis (2019) (14)
Calcineurin-induced energy wasting in a transgenic mouse model of heart failure. (2008) (14)
Identity Crisis for Regenerative Cardiac cKit+ Cells. (2017) (14)
Response to Torella et al. (2014) (13)
CARdiac Immunotherapy: T Cells Engineered to Treat the Fibrotic Heart. (2019) (13)
NFATc 3 and NFATc 4 Are Required for Cardiac Development and Mitochondrial Function (2003) (13)
Molecular analysis of HLA-DR beta and DQ beta polymorphism in Chinese with rheumatoid arthritis. (1993) (13)
Reply to Revisiting calcineurin and human heart failure (2000) (12)
Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active (2011) (12)
Magnetic resonance imaging assessment of cardiac dysfunction in δ-sarcoglycan null mice (2011) (12)
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity. (2020) (11)
Development of advanced analytical tools to determine the origin of caviar (2008) (11)
Calcineurin and NFAT 4 Induce Chondrogenesis * (2002) (10)
The transcription factor C/EBPbeta serves as a master regulator of physiologic cardiac hypertrophy. (2011) (10)
Apoptosis Repressor with a CARD Domain (ARC) Restrains Bax-Mediated Pathogenesis in Dystrophic Skeletal Muscle (2013) (10)
Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors. (2008) (10)
MEF2C repressor variant deregulation leads to cell cycle re-entry and development of heart failure (2020) (10)
Identity of the elusive mitochondrial permeability transition pore: what it might be, what it was, and what it still could be (2018) (9)
RCANs regulate the convergent roles of NFATc1 in bone homeostasis (2016) (9)
Mitsugumin 29 regulates t-tubule architecture in the failing heart (2017) (9)
The β isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside‐in αIIbβ3 integrin signaling (2014) (9)
Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia (2021) (8)
Genetic Reduction in Left Ventricular Protein Kinase C-&agr; and Adverse Ventricular Remodeling in Human Subjects (2018) (8)
Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy (2022) (8)
Hippo signaling does it again: arbitrating cardiac fibroblast identity and activation (2019) (7)
An acute immune response underlies the benefit of cardiac adult stem cell therapy (2018) (7)
Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons (2022) (7)
Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of Heart Failure With Reduced Ejection Fraction (2017) (7)
Cyclophilin D regulates necrosis, but not apoptosis, of murine eosinophils. (2016) (7)
Cardiac Cell Therapy Fails to Rejuvenate the Chronically Scarred Rodent Heart. (2021) (7)
Locating heart failure (2005) (7)
Stiffness of thermoresponsive gelatin-based dynamic hydrogels affects fibroblast activation (2019) (7)
CaMKII does it again: even the mitochondria cannot escape its influence. (2013) (7)
van Berlo et al. reply (2018) (6)
Author response: Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice (2013) (6)
FUNCTIONAL DIVERGENCE OF PLATELET PKC ISOFORMS IN THROMBUS FORMATION ON COLLAGEN* (2010) (5)
Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart (2016) (5)
Interleukin-1α dependent survival of cardiac fibroblasts is associated with StAR/STARD1 expression and improved cardiac remodeling and function after myocardial infarction. (2020) (5)
Fibroblasts orchestrate cellular crosstalk in the heart through the ECM (2022) (4)
Abstract 197: Overexpression of the Na+/K+ ATPase a2 But Not a1 Isoform Attenuates Pathological Cardiac Hypertrophy and Remodeling (2013) (4)
Fondation Leducq Transatlantic Network of Excellence Targeting Mitochondria to Treat Heart Disease. (2019) (4)
Cardiac Cell Therapy Rejuvenates the Infarcted Rodent Heart via Direct Injection but Not by Vascular Infusion. (2020) (4)
A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway (2020) (4)
Abstract 1386: Stem Cells Refresh Adult Mammalian Cardiomyocytes Following Injury: A Genetic Fate-Mapping Study (2006) (3)
Refined CLARITY-Based Tissue Clearing for Three-Dimensional Fibroblast Organization in Healthy and Injured Mouse Hearts. (2021) (3)
P 38 a MAPK underlies muscular dystrophy and myofiberdeaththroughaBax-dependentmechanism (2014) (3)
An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair. (2022) (3)
Satellite cell depletion in early adulthood attenuates muscular dystrophy pathogenesis (2019) (3)
Inhibition of p 38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion (2005) (3)
Corrigendum to “Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active” [Cell Signal 23 (2011) 468–477] (2011) (2)
Resident macrophages keep mitochondria running in the heart (2020) (2)
Applying Modern Transcriptomics to Interrogate the Human Cardiac Fibroblast∗ (2016) (2)
NOVEL BLOCKER OF NFAT ACTIVATION INHIBITS INTERLEUKIN-6 PRODUCTION IN HUMAN MYOMETRIAL ARTERIES AND REDUCES VASCULAR SMOOTH MUSCLE CELL PROLIFERATION (2006) (2)
Seroprevalence of SARS-CoV-2 infection in Cincinnati Ohio USA from August to December 2020 (2021) (2)
Helmut Drexler, MD, 1951-2009. (2009) (2)
Corrigendum: Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals (2012) (2)
Molecular analysis of HLA-DR , B and DQI 3 polymorphism in Chinese with rheumatoid arthritis (2004) (2)
Loss of Acta2 in cardiac fibroblasts does not prevent the myofibroblast differentiation or affect the cardiac repair after myocardial infarction (2021) (2)
DUSP6-Mediated Negative Feedback to Oncogenic Tyrosine Kinase Signaling Prevents Excessive Accumulation of ROS and Enables Leukemia Cell Survival (2011) (2)
, N early myogenic lineages . MEF 2 B is a potent transactivator expressed in (1996) (2)
IP3-induced calcium release engages a pro-hypertrophic autoamplifying loop that relieves miR-133a mediated suppression of IP3RII calcium channels (2012) (1)
An acute immune response underlies the benefit of cardiac stem cell therapy (2019) (1)
Critical Role for Cyclophilin D and the Mitochondrial Permeability Transition Pore (MPTP) in Platelet Activation. (2006) (1)
Cardiomyocyte-Specific TGF β Suppression Blocks Neutrophil Infiltration, Augments Multiple Cytoprotective Cascades, and Reduces Early Mortality after Myocardial Infarction (2014) (1)
Abstract 252: Activated Fibroblast-specific Deletion of RhoA Reduces Cardiac Fibrosis Through Regulation of the Non-canonical p38-MAPK Signaling Pathway (2019) (1)
Abstract 360: Differential Analysis of Thrombospondin Proteins in Cardiac Disease (2015) (1)
Spatial Gene Profiling in the Ischemic Heart: Fibroblasts Put on Their SOX (2017) (1)
Genetic analysis of CTGF as an effector of TGFβ signaling and cardiac (2015) (1)
Abstract 352: DnaJb5, an Hsp40 Family Protein, Mediates Antihypertrophic Effects of Thioredoxin1 in the Heart (2006) (1)
Deletion of cytosolic phospholipase A2 promotes striated muscle growth (2003) (1)
Rpl3l gene deletion in mice reduces heart weight over time (2023) (1)
Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart (2019) (1)
05 Inhibition of p38 mitogen-activated protein kinase (MAPK) leads to hypertrophic cardiomyopathy (2002) (1)
Abstract 918: Pre-B-cell Leukemia Homeobox Interacting Protein 1 is a Novel Regulator of Growth Signaling in the Heart (2019) (1)
Cav3.1/α1G T-Type Ca2+ Channels are Involved in the Heart Rate Regulation (2011) (1)
Abstract 2733: Enhanced Cav1.2 Influx Induces Cardiac Conduction Disturbances and SR Ca2+ Overload to Induce Cardiac Arrhythmia but With Shortened QT and Action Potentials (2009) (1)
Yolk sac macrophage progenitors traffic to the embryo during defined stages of development (2018) (1)
Targeted Loss of Cardiac L-type Ca2+ Ca(v)1.2 Channels in Adult Mouse Causes Sinus Node Dysfunction, AV block and Supraventricular Tachycardias (2008) (1)
Abstract 247: The Endothelial Transcription Factor GATA2 Prevents the Development of Heart Failure During Pressure Overload Through Suppression of the Two Secreted Long Non-coding RNAs GADLOR1 and 2 (2017) (1)
Interleukin-33 Mediates Cardiomyopathy After Acute Kidney Injury by Signaling to Cardiomyocytes (2023) (1)
Palmitoylation‐Dependent Regulation of RhoGTPase Signaling and Cardiac Pathophysiology (2019) (1)
Abstract 155: ATF6 is a Mediator of Cardiac Hypertrophy During Pressure Overload in the Mouse Heart (2017) (0)
Abstract 208: Down Regulation of the Novel Transcriptional Regulator of Cardiac Hypertrophy, Kruppel-Like Factor 15, is Mediated by TGF-Beta Induced p38 Activation in vivo and in vitro. (2006) (0)
13 GATA4 and dHAND physically interact to synergistically activate cardiac gene expression via A p300-dependent mechanism (2002) (0)
Abstract 1432: Cardiomyocyte Myostatin Contributes to Skeletal Muscle Wasting in Heart Failure (2008) (0)
Abstract 486: Role of the Adenine Nucleotide Translocator Family in the Mitochondrial Permeability Transition Pore (2018) (0)
Abstract 447: Targeted Overexpression of L-type Calcium Channel Beta2a Subunit Regulates Cardiac Hypertrophy and Death after Stress Stimulation (2006) (0)
Special Report Research Priorities in Hypertrophic Cardiomyopathy Report of a Working Group of the National Heart, Lung, and Blood Institute Genetic Cause (2010) (0)
A High‐Content RNAi Screen to Elucidate Novel Effectors of Cardiac Proteotoxicity (2016) (0)
Abstract 13015: Inhibition of Mitochondrial Calcium Uptake in the Heart Does Not Compromise Cardiac Energetics or Function Due to a Preferential Increase in Fatty Acid Oxidation During Increased Cardiac Work (2016) (0)
Abstract 1830: Protein Quality Control Inadequacy Activates NFAT Signaling in Cardiomyocytes (2008) (0)
Abstract 421: Activated Cardiac Myofibroblasts Can Revert Back to Become Resident Fibroblasts Upon Injury Cessation (2016) (0)
Abstract 2944: Targeting negative feedback signaling in tyrosine kinase-driven malignancies (2012) (0)
Calcium Sparklets Regulate Local and Global Calcium in Murine Arterial Smooth Muscle (0)
Heart function in adult cardiac Serca2null mice (2007) (0)
S-Palmitoylation-Dependent Regulation of Cardiomyocyte Rac1 Signaling Activity and Cardiac Hypertrophy (2021) (0)
Inhibition of Calcineurin and Sarcolemmal Ca 2 (cid:1) Influx Protects Cardiac Morphology and Ventricular Function in K v 4.2N Transgenic Mice (2002) (0)
The Embryonic Mitochondrial Permeability Transition Pore Controls Cardiac Myocyte Mitochondrial Maturation and Differentiation (2011) (0)
Excess Ca2+ Influx through the L-Type Ca2+ Channel Exacerbates Ischemia-Induced Cardiac Damage (2007) (0)
Cardiac Myosin Binding Protein-C Phosphorylation in a (cid:1) -Myosin Heavy Chain Background Molecular Cardiology (2009) (0)
Abstract 1579: Critical Role of the CaMKII-site (Ser282) in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function (2008) (0)
Abstract 13760: A Caveolin Targeted L-type Ca2+ Channel Antagonist Inhibits Hypertrophic Signaling Without Reducing Contractility of Cardiac Myocytes (2011) (0)
Abstract 159: Cardiac Hypertrophy and Sudden Death in a Mouse Model of STIM1 Overexpression (2013) (0)
Abstract 15606: Genome-wide Loss-of-Function Screen Identifies SNARE Proteins as a Central Component of Programmed Necrosis (2013) (0)
The necroptotic pathway and mitochondrial involvement. (2015) (0)
eccentric contractions E-C coupling failure in mouse EDL muscle after in vivo (2015) (0)
Cardiac fibroblasts regulate cardiomyocyte hypertrophy through dynamic regulation of type I collagen (2022) (0)
Cardiac-specific expression of GSK-3 impairs cardiac growth and calcium handling, leading to systolic and diastolic dysfunction, heart failure, and premature death (2003) (0)
proteins during development of heart failure Exercise training normalizes altered calcium-handling (2015) (0)
Abstract 19709: Increasing Ca2+ Influx After Myocardial Infarction Improves Myocyte Contractility but Depresses Cardiac Pump Function by Increasing Myocyte Death (2010) (0)
Abstract 195: Increases in Ca2+Influx through the L-type Ca2+Channel Induces Pathological Cardiomyocyte Hypertrophy (2007) (0)
Abstract 1382: The EF-hand Protein Calmyrin is a Novel Negative Regulator of Cardiac Myocyte Hypertrophy and Cell Death (2006) (0)
Abstract 3013: Identification of Novel Genes Directly Upregulated by Class II Histone Deacetylases (2009) (0)
Abstract 548: Evolutionarily Conserved Functions for Valosin Containing Protein (VCP) in Cardiac and Skeletal Muscle Reveal Mechanistic Insights into Multisystem Proteinopathy (2018) (0)
Abstract 183: A Genomewide Screen to Identify Novel NFAT Regulators (2012) (0)
p97 is Critical for Cardiac Proteostasis and Dysregulation of p97 Activity Causes Cardiomyopathy (2016) (0)
Abstract 264: p38 Regulates Programmed Myofibroblast Differentiation and Fibrosis (2017) (0)
Abstract 16436: Genetic Loss of Periostin Protects Against Atherosclerotic Lesion Formation (2012) (0)
Abstract 27: Loss of GATA4 in Kit Lineage-derived Endothelium Leads to Vascular Permeability and Increased Heterotypic Fusion (2017) (0)
Abstract 173: The Role of Bax and Bak in Autophagic Cell Death (2015) (0)
Abstract 3639: Enhanced Contractility but Reduced Excitation-contraction Coupling Efficiency and Adrenergic Reserve in Hearts With Increased Cav1.2 Activities (2009) (0)
Association Animal Models of Heart Failure : A Scientific Statement From the American Heart (2012) (0)
Cardiomyocyte-specific Excision of the Adult Mice with Inducible Moderate Calcium Channel Dysfunction in Membrane Biology : (2011) (0)
Abstract 14917: Cardiac Lineage Tracing Analysis at Baseline and With Injury Using Inducible C-kit-cre Knockin Mice (2013) (0)
Abstract 362: Deletion of Gata4 and Gata6 in the c-Kit Lineage Augments Cellular Fusion in vivo (2016) (0)
Nuclear calcineurin is a sensor for detecting Ca2+ release from the nuclear envelope via IP3R (2018) (0)
Abstract 278: Exercise Training Ameliorates LV Dysfunction in Mice with a Calcium Influx Mediated Cardiomyopathy (2013) (0)
WITHDRAWN: Heart function in adult cardiac Serca2null mice (2007) (0)
Impaired hypertrophic response in calcineurin Aβ-deficient mice (2001) (0)
Inhibiting Fibronectin Improves Cardiac Function in a Mouse Model of Heart Failure (2016) (0)
Egr1-Rcan1 axis serves as a molecular switch from activation to inhibition in IgE-mediated signalling (139.3) (2009) (0)
Abstract 205: Overexpression of the Mitochondrial F o F 1 ATP Synthase regulators ATP12 and ATP5J are Protective against Ischemia-Reperfusion Injury in the Heart (2017) (0)
Abstract 287: Cardioprotection in Mice With a Knock-in Mutation (C202S) in Cyclophilin D (2018) (0)
Author response: Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak (2017) (0)
Organ transplantation (WS-076) Chairpersons: Susumu Ikehara, Jorge Kalil (2010) (0)
Enhancement of the Cav3.1 Channel Activity by PKA in Ventricular Myocytes of a1G Transgenic Mice (2009) (0)
Abstracts from Rambam Research Day, December 11, 2014 (2015) (0)
Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy (2021) (0)
Abstract 158: Assessing the Paracrine Hypothesis in Cardiac Regeneration Through Endogenous c-Kit+ Cells (2015) (0)
Molecular analysis ofHLA-DR,B andDQI3 polymorphism inChinese withrheumatoid arthritis (1993) (0)
ENDOTOXIN TOLERANCE IS MEDIATED BY MKP‐1 REGULATION OF THE p38 KINASE.: 64 (2004) (0)
Calcineurin Deficiency Decreases Inflammatory Lesions in TGFbeta1‐deficient Mice (2008) (0)
Abstract 14917: Endogenous c-kit dependent genetic lineage tracing shows definable but limited contribution to cardiomyocyte regeneration. (2013) (0)
Abstract 143: A Novel TAK1 Signaling Network Regulating Programmed Necrosis and Myocardial Remodeling (2013) (0)
Decreased L-Type Ca2+ Channel Activity Does Not Alleviate the Development of Cardiac Hypertrophy and Progression to Heart Failure (2009) (0)
Protein Kinase C (cid:1) , but Not PKC (cid:2) or PKC (cid:3) , Regulates Contractility and Heart Failure Susceptibility Implications for Ruboxistaurin as a Novel Therapeutic Approach (2009) (0)
Abstract P485: Loss Of Acta2 In Cardiac Fibroblasts Does Not Prevent The Myofibroblast Differentiation Or Affect The Cardiac Repair After Myocardial Infarction (2021) (0)
P-348 Periostin, Secreted Extracellular Matrix Protein, Plays a Critical Role in Cardiac Hypertrophy and Ventricular Remodeling (2009) (0)
Characterization of protein kinase C (PKC) function in cardiomyocyte hypertrophy (2001) (0)
The Dual-Specificity Phosphatase MKP-1 Limits the Cardiac Hypertrophic Response In Vitro and In Vivo Integrative (2000) (0)
Abstract 13824: Impact of the Transcription Factor GATA2 in Endothelial Cells on the Development of Heart Failure Through the Regulation of Two Secreted Long Non-Coding RNAs (2014) (0)
Abstract 168: Does Calcium Influx Through TTCC Induce Cardiomyocyte Proliferation? (2012) (0)
Abstract 74: The Role of Fibroblast-specific Canonical Tgfβ Signaling in Cardiac Fibrosis (2015) (0)
Abstract 306: Identifying Downstream Effectors of the Extracellular Signal-related Kinase 1/2-controlled Directional Growth Response in Cardiomyocytes (2018) (0)
Abstract 323: Re-expression of T-type Calcium Current in the Heart Protects from Stress-induced Hypertrophy and Heart Failure (2007) (0)
Calcineurin Aβ null partially rescues impaired cardiac function in targeted overexpression of L-LVDCC α1C (2007) (0)
Abstract MP124: De-palmitoylation of Cysteine 202 of Cyclophilin-D by Calcium is Important for the Activation of the Permeability Transition Pore (2020) (0)
Abstract 222: Sigmar1 Mediates Mitochondrial Autophagy and Protects the Heart Against Ischemia/Reperfusion Injury (2016) (0)
423 Genome wide expression profiling of NFAT transcriptional activity in a ventricular muscle cell line identifies GATA4 as an NFAT target gene in a feedforward mechanism driving cardiomyocyte hypertrophy (2006) (0)
C1qbp localizes to mitochondria and protects against oxidative stress‐induced mitochondrial dysfunction and cell death (2009) (0)
Abstract 1247: Heart Function is Transiently Sustained Despite a Near Loss of SERCA2 Protein in Cardiomyocyte-specific Serca2null Mice (2007) (0)
Calcineurin mediates bile-acid induced pancreatitis (2012) (0)
Abstract 18518: Impaired Cardiac Function and Heart Failure in Transgenic Mice With Cardiac Specific Overexpression of Hasf, a Novel Stem Cell Paracrine Factor (2010) (0)
Heart failure: unexpected role of stem cell treatments (2020) (0)
Effects of Glucocorticoids in Murine Models of Duchenne and Limb-Girdle Muscular Dystrophy. (2023) (0)
Mortality After Myocardial Infarction Conditional Transgenic Expression of Fibroblast Growth Factor 9 in the Adult Mouse (2011) (0)
Loss of the Mitochondrial Sodium/Calcium Exchanger in the Adult Heart Causes Sudden Death and Overexpression Protects Against Heart Failure (2016) (0)
BEX1 is an RNA-dependent mediator of cardiomyopathy (2017) (0)
Abstract 186: Increased STIM1 Expression Results in Altered Calcium Handling and Heart Failure (2015) (0)
Correction (2004) (0)
Evidence for minimal cardiogenic potential of Sca-1 positive cells in the adult mouse heart (2018) (0)
Abstract 296: Fibroblast Proliferation Dynamics in the Mouse Heart with Myocardial Infarction Injury in vivo (2017) (0)
Remembering Jeff Robbins (2022) (0)
Abstract 383: Cavβ2a Transgenic Mouse as a Hfpef Model With Hypercontractile Cardiomyocytes (2020) (0)
A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy. (2023) (0)
Abstract 16518: Inhibition of Inositol (1,4,5)-Trisphosphate Signaling in the Mouse Heart Attenuates Cardiac Hypertrophy after GPCR Stimulation. (2010) (0)
Negative Feedback Signaling Enables Leukemic Transformation by Oncogenic Tyrosine Kinases (2012) (0)
Abstract 19645: Cardiac Effects of Physiological Hypertrophy in a Murine Model of Calcium Channel Overexpression (2012) (0)
Thrombospondin 1 : a master regulator of the anti-oxidant defence in pancreatic beta cells (2015) (0)
Cardiac-specific Deletion of RhoA Restores Cardiac Function in a Mouse Model of Type 1 Diabetes (2017) (0)
Abstract 422: Small Molecule and Activated Fibroblast Targeting of the Gβγ-GRK2 Interface After Myocardial Ischemia Attenuates Heart Failure Progression (2017) (0)
Abstract 164: Microdomain Specific Effects of Transient Receptor Potential Channels on Pathological Cardiac Hypertrophy and Myocyte Contractility (2013) (0)
Abstract 380: Resident Cardiac Fibroblasts Give Rise to Periostin+ Myofibroblasts Which are the Primary Mediators of Cardiac Fibrosis (2015) (0)
Author response: Thrombospondin expression in myofibers stabilizes muscle membranes (2016) (0)
Erratum: Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy (Circulation Research (2013) 112 (48-56) DOI: 10.1161/CIRCRESAHA.112.272963) (2013) (0)
Survival of Naive T Cells for the b Requirement of Calcineurin A (0)
modulation of erythropoiesis mice reveals a mechanism for apoptotic-/-Unrestrained erythroblast development in Nix (2007) (0)
Abstract 837: Different Disease States in Heart Have Distinct Cardiac Interstitial Cells Contributing to Fibrosis (2019) (0)
Abstract 283: Redox-mediated Regulation of Histone deacetylase4, a Class II HDAC, by Thioredoxin1 through Interaction with DnaJb5, a Heat Shock Protein 40 (2007) (0)
Abstract 1834: Inducible Overexpression of Inositol(1,4,5)-trisphosphate receptor type 2 in the Mouse Heart induces Cardiac Hypertrophy (2008) (0)
Abstract 1605: T-Type Calcium Current Activates Pro-Survival Signaling Pathways after Myocardial Infarction (2008) (0)
Loss of NF-ATc3, not NF-ATc4, attenuates cardiac hypertrophy induced by calcineurin activation in vivo (2001) (0)
Calcineurin Ab deficiency causes defective Treg-cell generation and enhanced effector T-cell differentiation (89.13) (2009) (0)
Inhibition of PKC (cid:1) / (cid:2) With Ruboxistaurin Antagonizes Heart Failure in Pigs After Myocardial Infarction Injury (2011) (0)
Book Review Exploring Genetic Mechanisms Edited by Maxine Singer and Paul Berg. 674 pp., illustrated. Sausalito, Calif., University Science Books, 1997. $86.50. 0-935702-70-9 (1997) (0)
MO289: IL33 Exerts Toxicity in the Heart as Secreted by Renal Inflammation (2022) (0)
Abstract 3498: Targeted Loss of Cardiac L-type Ca2+ Cav1.2 Channels in Adult Mouse Causes Sinus Node Dysfunction, AV block and Supraventricular Tachycardias (2008) (0)
Abstract 19564: Cardiomyocyte Overexpression of the Mitochondrial Sodium/Calcium Exchanger Increases Matrix Calcium Efflux and Preserves Cardiac Function in Mouse Models of Heart Failure (2014) (0)
Abstract 12192: MBNL1 Directly Regulates the Alternative Splicing of mRNAs That Promote Myofibroblast Differentiation (2014) (0)
Abstract 352: Dual Specificity Phosphatase 8 (dusp8) Regulates Cardiac Remodeling and Function by Affecting Erk1/2 Phosphorylation (2015) (0)
muscle 3 mo after coronary artery ligation -ATPase properties in rat heart and skeletal (2015) (0)
Abstract P290: RhoA Protects Against Myocardial Ischemia/Reperfusion Injury (2011) (0)
Abstract 47: GATA Factors Caught at a Crossroad of Gene Duplication with Functional Divergence (2012) (0)
At the Brink of Human Therapy to Generate New Myocytes in the Adult Injured Heart. (2022) (0)
Abstract 181: Rescue of the Cardiac Phenotype of Noonan Syndrome In Vivo by Ablation of Cardiac ERK1/2 Signaling (2006) (0)
Abstract 205: Differing Cardiac Phenotypes Between PP1α and PP1β Heart-Specific Gene-Deleted Mice (2012) (0)
Abstract 1067: CamKII Regulates NFAT Nuclear Translocation in a Calcineurin Independent Manner (2007) (0)
Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability (2019) (0)
Abstract 310: Nix in the Heart: Regulation of Developmental Apoptosis and Sarcoplasmic Reticular Calcium Stores Explains its Functional Diversity (2006) (0)
Molkentin and Autophagy in Cardiomyocytes FoxO Transcription Factors Promote Mechanisms of Signal Transduction (2009) (0)
Abstract 44: NSF is Required for Plasma Membrane Blebbing Occurring in Necrotic Cell Death (2017) (0)
Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids (2021) (0)
INHIBITION OF CARDIAC FIBROSIS MEDIATED BY NON-MYOCYTE PROLIFERATION IN HYPERTROPHIC CARDIOMYOPATHY (2010) (0)
New Leaders in Cardiovascular Science (2014) (0)
Abstract 305: Single Cell RNA Sequencing of Adult Cardiac c-kit+ Cells in a Murine Lineage Tracing Model (2015) (0)
Effects of Cardiac Specific Inhibition of TRPC Channels on Cardiac Hypertrophy and Ca2+ Handling (2010) (0)
Cavβ2a TG mice treated with hight fat diet and L‐Name is a model for HFpEF (2021) (0)
Abstract 104: Activated Cardiac Fibroblast Can Deactivate to Become Resting Fibroblasts Upon Injury Resolution (2017) (0)
725 Periostin Facilitates Eosinophil Tissue Infiltration In Vivo and In Vitro (2008) (0)
Increases in Ca Influx Induces Cardiomyocyte Hypertrophy In Vitro and In Vivo (2007) (0)
Abstract 205: Differing Cardiac Phenotypes Between PP1{alpha} and PP1{beta} Heart-Specific Gene-Deleted Mice (2012) (0)
Abstract 18563: Sigmar1 Protects the Heart Against Ischemia/Reperfusion Injury (2016) (0)
282 The MEK1-ERK2 signaling pathway protects cardiomyocytes from ischemic damage in vivo (2004) (0)
Abstract 5308: T and L-type Ca2+ Currents Differentially Regulate Myocardial Ischemia-Reperfusion Tolerance (2008) (0)
Results Transient PTP Openings in Single Mitochondria During Cyclic Sarcoplasmic Reticulum Ca (2016) (0)
IP3 Receptor-mediated Ca Release Facilitates RyR-Ca Release To Cause Inotropy And Arrhythmogenicity In Mouse Ventricular Myocytes (2009) (0)
Abstract 3222: When the L-type Ca2+ Current is Increased After Myocardial Infarction Determines if the Effects Will be Beneficial or Detrimental (2009) (0)
UltraRapid Communication A Caveolae-Targeted L-Type Ca 2 Channel Antagonist Inhibits Hypertrophic Signaling Without Reducing Cardiac Contractility (2017) (0)
Abstract 93: Genetic Deletion of Slc8b1, the Mitochondrial Sodium/Calcium Exchanger, Causes Sudden Cardiac Death and Overexpression Protects Against Myocardial Infarction and Pressure-Overload Heart Failure (2015) (0)
Abstract P074: Loss of Function of TRPC4 Protects Against Cardiac Dysfunction Progression After Myocardial Infarction (2011) (0)
Role of UBC 9 in the Unfolded Protein Response Using an Endoplasmic Reticulum Stress Response Element Reporter (2014) (0)
Abstract 828: The Functional Role of Myofibroblast-Expressed Smooth Muscle Alpha Actin in Post-Myocardial Infarction Tissue Healing (2019) (0)
Abstract 546: Exploring MCUb Function in the Heart and Its Role in Ischemia Reperfusion Injury (2019) (0)
Mitogen-Activated Protein Kinase-Dependent Fiber-Type Regulation in Skeletal Muscle (2018) (0)
Abstract 200: Cardiomyocyte-specific Deletion Of Rhoa Accelerates Heart Failure But Prevents Cardiac Fibrosis In Response To Pressure-overload (2013) (0)
Abstract 11418: Fibrosis and Calcium Signaling Regulation Are Critical Mechanisms in a Three-Hit HFpEF Mouse Model (2021) (0)
Mitsugumin 29 regulates t-tubule architecture in the failing heart (2017) (0)
Pharmacologic- and gene therapeutic-based inhibition of PKC α / β enhances cardiac contractility and attenuates heart failure (2009) (0)
A120. Activation of the calcineurin-NFAT pathway in desminopathy mouse hearts: The role of proteasomal malfunction (2006) (0)
Abstract 1783: Pro-Apoptotic Bnip3 Mediates Permeabilization of Mitochondria and Release of Cytocrome c via a Novel Mechanism (2008) (0)
Abstract 111: High Activity Gating of Caveolae-Targeted L-Type Ca2+ Channels Can Initiate Pathological Hypertrophy (2012) (0)
Integrative Physiology Inhibition of PKC / With Ruboxistaurin Antagonizes Heart Failure in Pigs After Myocardial Infarction Injury Short Communication (2011) (0)
Abstract 412: Dissection of Thrombospondin-4 Domains Involved in Adaptive ER Stress Responsive Signaling and Secretory Pathway Functions (2015) (0)

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