Jeffrey M. Friedman
Physician scientist studying the genetic mechanisms that regulate body weight.
Jeffrey M. Friedman's AcademicInfluence.com Rankings
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Biology Philosophy
Jeffrey M. Friedman's Degrees
- Doctorate Medicine Albany Medical College
Why Is Jeffrey M. Friedman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jeffrey M. Friedman is a molecular geneticist at New York City's Rockefeller University and an Investigator of the Howard Hughes Medical Institute. His discovery of the hormone leptin and its role in regulating body weight has had a major role in the area of human obesity. Friedman is a physician scientist studying the genetic mechanisms that regulate body weight. His research on various aspects of obesity received national attention in late 1994, when it was announced that he and his colleagues had isolated the mouse ob gene and its human homologue. They subsequently found that injections of the encoded protein, leptin, decreases body weight of mice by reducing food intake and increasing energy expenditure. Current research is aimed at understanding the genetic basis of obesity in human and the mechanisms by which leptin transmits its weight-reducing signal.
Jeffrey M. Friedman's Published Works
Published Works
- Positional cloning of the mouse obese gene and its human homologue (1994) (10427)
- Positional cloning of the mouse obese gene and its human homologue (1995) (7803)
- Leptin and the regulation of body weight in mammals (1998) (5411)
- Weight-reducing effects of the plasma protein encoded by the obese gene. (1995) (4757)
- Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects (1995) (3870)
- The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis (2003) (1599)
- Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. (2006) (1346)
- Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor (2000) (1265)
- A genetic map of the mouse suitable for typing intraspecific crosses. (1992) (1142)
- Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice (1996) (1106)
- Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. (1997) (1052)
- Loss of stearoyl–CoA desaturase-1 function protects mice against adiposity (2002) (1021)
- Rapid Rewiring of Arcuate Nucleus Feeding Circuits by Leptin (2004) (969)
- Rapid regulation of depression-related behaviors by control of midbrain dopamine neurons (2012) (854)
- Identification of White Adipocyte Progenitor Cells In Vivo (2008) (833)
- Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. (1997) (797)
- Role for Stearoyl-CoA Desaturase-1 in Leptin-Mediated Weight Loss (2002) (776)
- Abnormal osmotic regulation in trpv4-/- mice (2003) (733)
- Acute stimulation of glucose metabolism in mice by leptin treatment (1997) (732)
- Obesity in the new millennium (2000) (730)
- Selective deletion of leptin receptor in neurons leads to obesity. (2001) (587)
- Leptin-specific patterns of gene expression in white adipose tissue. (2000) (526)
- The function of leptin in nutrition, weight, and physiology. (2002) (516)
- Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. (1995) (502)
- Whole population, genome-wide mapping of hidden relatedness. (2009) (426)
- Leptin targets in the mouse brain (2009) (424)
- Peroxisome Proliferator-Activated Receptor γ Target Gene Encoding a Novel Angiopoietin-Related Protein Associated with Adipose Differentiation (2000) (406)
- Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes (2004) (404)
- Radio-Wave Heating of Iron Oxide Nanoparticles Can Regulate Plasma Glucose in Mice (2012) (402)
- Leptin, leptin receptors and the control of body weight. (2009) (400)
- Distinct Transcriptional Profiles of Adipogenesisin Vivo and in Vitro * (2001) (394)
- A War on Obesity, Not the Obese (2003) (391)
- Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. (2004) (381)
- Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake (2006) (375)
- Virus-Assisted Mapping of Neural Inputs to a Feeding Center in the Hypothalamus (2001) (371)
- Transgenic Mice Expressing Green Fluorescent Protein under the Control of the Melanocortin-4 Receptor Promoter (2003) (364)
- Modern science versus the stigma of obesity (2004) (357)
- Optogenetic identification of a rapid-eye-movement (REM) sleep modulatory circuit in the hypothalamus (2013) (348)
- Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans (2003) (335)
- The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. (2009) (331)
- Sympathetic Neuro-adipose Connections Mediate Leptin-Driven Lipolysis (2015) (323)
- Expression of ob Gene in Adipose Cells (1996) (309)
- Transcriptional regulation of adipogenesis by KLF4. (2008) (307)
- Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons. (2011) (295)
- Topographic mapping of VMH → arcuate nucleus microcircuits and their reorganization by fasting (2005) (293)
- A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. (2007) (290)
- Leptin at 14 y of age: an ongoing story. (2009) (278)
- Hyperleptinemia Is Required for the Development of Leptin Resistance (2010) (273)
- Molecular Profiling of Activated Neurons by Phosphorylated Ribosome Capture (2012) (264)
- Relatively low plasma leptin concentrations precede weight gain in Pima Indians (1997) (262)
- The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7. (1995) (255)
- Antidiabetic effects of IGFBP2, a leptin-regulated gene. (2010) (250)
- Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells. (2009) (243)
- Obesity: Causes and control of excess body fat (2009) (223)
- Leptin regulates the reward value of nutrient (2011) (217)
- Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms. (2005) (209)
- Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase. (1997) (208)
- Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. (2004) (201)
- Identification and Characterization of Murine SCD4, a Novel Heart-specific Stearoyl-CoA Desaturase Isoform Regulated by Leptin and Dietary Factors* (2003) (199)
- Leptin and the endocrine control of energy balance (2019) (192)
- The long road to leptin. (2016) (191)
- Neuropeptide Y-Mediated Inhibition of Proopiomelanocortin Neurons in the Arcuate Nucleus Shows Enhanced Desensitization in ob/ob Mice (2004) (190)
- Absence of Mutations in the Human OB Gene in Obese/Diabetic Subjects (1996) (189)
- The alphabet of weight control (1997) (182)
- Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism (2016) (181)
- Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway (2013) (177)
- Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction. (1999) (176)
- Molecular mapping of the mouse ob mutation. (1991) (176)
- Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically (2010) (171)
- 20 years of leptin: leptin at 20: an overview. (2014) (170)
- Xanthine Oxidoreductase Is a Regulator of Adipogenesis and PPARγ Activity (2007) (164)
- Krüppel-like Factor-6 Promotes Preadipocyte Differentiation through Histone Deacetylase 3-dependent Repression of DLK1* (2005) (164)
- Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles (2014) (162)
- Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1). (2004) (162)
- MicroRNAs: critical mediators of differentiation, development and disease. (2009) (152)
- Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. (2005) (150)
- Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db). (1991) (148)
- Leptin and the regulation of body weight. (2010) (144)
- Common SNPs in HMGCR in Micronesians and Whites Associated With LDL-Cholesterol Levels Affect Alternative Splicing of Exon13 (2008) (140)
- Human leptin characterization (1996) (134)
- Leptin and the regulation of body weigh. (2011) (130)
- Abnormal regulation of the leptin gene in the pathogenesis of obesity. (1998) (129)
- Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar (2013) (124)
- Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae (2009) (117)
- Molecular Profiling of Neurons Based on Connectivity (2014) (117)
- Late-Onset Leanness in Mice with Targeted Ablation of Melanin Concentrating Hormone Neurons (2006) (117)
- Tackling a weighty problem (1992) (117)
- Neuropeptide Y Y1 receptor mRNA in rodent brain: Distribution and colocalization with melanocortin‐4 receptor (2005) (117)
- A leptin–BDNF pathway regulating sympathetic innervation of adipose tissue (2020) (114)
- Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity (2003) (111)
- Use of Laser-Capture Microdissection for the Identification of Marker Genes for the Ventromedial Hypothalamic Nucleus (2005) (105)
- Identification of a Brainstem Circuit Controlling Feeding (2017) (104)
- Stearoyl-CoA desaturase-1 and the metabolic syndrome. (2003) (101)
- Mediator MED23 links insulin signaling to the adipogenesis transcription cascade. (2009) (99)
- Molecular mapping of the mouse db mutation. (1990) (98)
- Acute intravenous leptin infusion increases glucose turnover but not skeletal muscle glucose uptake in ob/ob mice. (1999) (93)
- Induction of Leptin Receptor Expression in the Liver by Leptin and Food Deprivation* (2005) (93)
- Absence of Soluble Leptin Receptor in Plasma fromdb Pas /db Pas and Otherdb/db Mice* (1998) (92)
- Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin. (2005) (92)
- Transcriptional and post-transcriptional control of specific messenger RNAs in adult and embryonic liver. (1984) (90)
- Profiling of Glucose-Sensing Neurons Reveals that GHRH Neurons Are Activated by Hypoglycemia. (2013) (90)
- Acute leptin deficiency, leptin resistance, and the physiologic response to leptin withdrawal. (2005) (89)
- Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity. (2007) (88)
- Gene expression during liver regeneration. (1984) (88)
- Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFα (2002) (87)
- Epidemiology and Factor Analysis of Obesity, Type II Diabetes, Hypertension, and Dyslipidemia (Syndrome X) on the Island of Kosrae, Federated States of Micronesia (2000) (86)
- Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia. (2006) (80)
- Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae. (2009) (79)
- Contrasting Effects of Leptin on Food Anticipatory and Total Locomotor Activity (2011) (79)
- The molecular basis of the obese mutation in ob2J mice. (1997) (77)
- Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis (2011) (77)
- Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia (2006) (74)
- Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake. (2015) (73)
- Identification of cathepsin K as a novel marker of adiposity in white adipose tissue (2003) (73)
- DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation. (2011) (72)
- Cellular promoters incorporated into the adenovirus genome: cell specificity of albumin and immunoglobulin expression (1986) (70)
- Diabetes: Fat in all the wrong places (2002) (69)
- Epigenetic Alterations and MicroRNA Misexpression in Cancer and Autoimmune Diseases: a Critical Review (2014) (69)
- Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity (2019) (68)
- Site-specific (18)F-labeling of the protein hormone leptin using a general two-step ligation procedure. (2008) (66)
- Melanocortin‐4 receptor expression in a vago‐vagal circuitry involved in postprandial functions (2010) (64)
- A tale of two hormones (2010) (63)
- Transcriptional regulation of the albumin gene in cultured rat hepatocytes. Role of basement-membrane matrix. (1990) (62)
- Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels (2009) (62)
- Ablation of AgRP neurons impairs adaption to restricted feeding (2014) (62)
- 20 years of leptin: from the discovery of the leptin gene to leptin in our therapeutic armamentarium. (2015) (61)
- Transgenic mice expressing green fluorescent protein under the control of the corticotropin-releasing hormone promoter. (2009) (61)
- Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP. (2017) (59)
- A critical role for mTORC1 in erythropoiesis and anemia (2014) (58)
- PET imaging of leptin biodistribution and metabolism in rodents and primates. (2009) (53)
- Differential expression of the mouse cholecystokinin gene during brain and gut development. (1985) (50)
- Phenotypic effects of an induced mutation of the ObRa isoform of the leptin receptor. (2013) (49)
- Insulin regulates leptin secretion from 3T3-L1 adipocytes by a PI 3 kinase independent mechanism. (2008) (47)
- Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia. (2002) (46)
- Cellular promoters incorporated into the adenovirus genome: effects of viral regulatory elements on transcription rates and cell specificity of albumin and beta-globin promoters (1986) (46)
- Regulation of Energy Expenditure by Brainstem GABA Neurons (2019) (45)
- α1- and β3-Adrenergic Receptor–Mediated Mesolimbic Homeostatic Plasticity Confers Resilience to Social Stress in Susceptible Mice (2019) (44)
- A Role of Drd2 Hippocampal Neurons in Context-Dependent Food Intake (2019) (43)
- The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the Polycomb group protein EZH2 in cancer (2009) (42)
- Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. (2003) (40)
- Molecular genetic linkage maps of mouse chromosomes 4 and 6. (1991) (39)
- Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach (2008) (38)
- Gene Expression Profiling with Cre-Conditional Pseudorabies Virus Reveals a Subset of Midbrain Neurons That Participate in Reward Circuitry (2017) (36)
- Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression (2015) (35)
- Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population. (2011) (34)
- Molecular genetics of the brown (b)-locus region of mouse chromosome 4. I. Origin and molecular mapping of radiation- and chemical-induced lethal brown deletions. (1994) (31)
- Molecular mapping of obesity genes (2004) (30)
- Leptin at 20: an overview (2014) (29)
- Molecular characterization of neuronal cell types based on patterns of projection with Retro-TRAP (2015) (27)
- A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass (2018) (27)
- Molecular annotation of integrative feeding neural circuits. (2011) (27)
- Functional analysis reveals differential effects of glutamate and MCH neuropeptide in MCH neurons (2018) (25)
- Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae (2009) (25)
- Molecular cloning of the mouse CCK gene: expression in different brain regions and during cortical development (1991) (25)
- Level of expression and chromosome mapping of the mouse cholecystokinin gene: implications for murine models of genetic obesity. (1989) (24)
- Phytosterolemia on the island of Kosrae: founder effect for a novel ABCG8 mutation results in high carrier rate and increased plasma plant sterol levels. (2004) (24)
- The genetic structure of the Turkish population reveals high levels of variation and admixture (2021) (22)
- Obese Locus in WNIN/Obese Rat Maps on Chromosome 5 Upstream of Leptin Receptor (2013) (22)
- Expression of the cholecystokinin gene in pediatric tumors. (1992) (21)
- Leptin receptor mutations in 129 db3J/db3J mice and NIH facp/facp rats. (1997) (21)
- Regulation of N-myc gene expression: use of an adenovirus vector to demonstrate posttranscriptional control (1990) (20)
- The reward value of sucrose in leptin-deficient obese mice☆ (2013) (20)
- Genetic variation and nutrition in obesity: approaches to the molecular genetics of obesity. (1990) (20)
- A limbic circuit selectively links active escape to food suppression (2020) (20)
- Leptin, leptin receptors, and the control of body weight. (1998) (20)
- Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake. (2016) (19)
- Expression of the cholecystokinin gene by cultured human primitive neuroepithelioma cell lines. (1989) (18)
- Reanalysis of parabiosis of obesity mutants in the age of leptin (2015) (17)
- DNase I-hypersensitive sites in the 5'-flanking region of the rat serum albumin gene: correlation between chromatin structure and transcriptional activity. (1986) (17)
- Strategies for the molecular genetic analysis of obesity in humans. (1993) (17)
- Cytokine-induced Patterns of Gene Expression in Skeletal Muscle Tissue* (2003) (16)
- Genetic Analysis of Complex Disorders (1991) (15)
- Cellular promoters incorporated into the adenovirus genome. Effect of viral DNA replication on endogenous and exogenous gene transcription. (1987) (15)
- Control of non-homeostatic feeding in sated mice using associative learning of contextual food cues (2018) (15)
- Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones. (1993) (15)
- European admixture on the Micronesian island of Kosrae: lessons from complete genetic information (2009) (14)
- Molecular and cellular characterization of nicotinic acetylcholine receptor subtypes in the arcuate nucleus of the mouse hypothalamus (2018) (14)
- Developmental Role for Endocannabinoid Signaling in Regulating Glucose Metabolism and Growth (2013) (14)
- Leptin receptor mutations in 129 db3J/db3.J mice and NIH facp/facp rats (1997) (13)
- Electromagnetic Regulation of Cell Activity. (2018) (13)
- Top-down control of conditioned overconsumption is mediated by insular cortex Nos1 neurons. (2021) (12)
- A General Method for Insertion of Functional Proteins within Proteins via Combinatorial Selection of Permissive Junctions. (2015) (12)
- Plasmonic activation of gold nanorods for remote stimulation of calcium signaling and protein expression in HEK 293T cells (2016) (12)
- Uncovering a possible role of reactive oxygen species in magnetogenetics (2020) (12)
- Continuous Fatty Acid Oxidation and Reduced Fat Storage in Mice Lacking Acetyl-CoA Carboxylase 2 (2008) (11)
- Gut-to-brain signals in feeding control. (2020) (11)
- The mouse Cebp gene encoding a DNA-binding protein is polymorphic and is located on chromosome 7. (1989) (10)
- Microdissection of proximal mouse Chromosome 6: identification of RFLPs tightly linked to the ob mutation (1993) (10)
- Genetic analysis of complex disorders. Molecular mapping of obesity genes in mice and humans. (1991) (10)
- The alpha 2 chain of type 1 collagen does not map to mouse chromosome 16 but maps close to the Met proto-oncogene on mouse chromosome 6. (1989) (10)
- Molecular mapping of mouse chromosomes 4 and 6: use of a flow-sorted Robertsonian chromosome. (1992) (10)
- Molecular profiling of reticular gigantocellularis neurons indicates that eNOS modulates environmentally dependent levels of arousal (2018) (10)
- Creating a flexible multiple microRNA expression vector by linking precursor microRNAs. (2011) (10)
- Brown fat and yellow mice (1993) (10)
- Functional Analysis of Distinct Populations of Subthalamic Nucleus Neurons on Parkinson’s Disease and OCD-like Behaviors in Mice (2020) (9)
- Hepatoma variants (C2) are defective for transcriptional and post‐transcriptional actions from both endogenous and viral genomes. (1987) (9)
- Mouse chromosome 4 (2004) (9)
- Brainstem ADCYAP1+ neurons control multiple aspects of sickness behaviour (2022) (8)
- Brachytherapy catheter spacing and stabilization technique. (2012) (8)
- Higher-Order Inputs Involved in Appetite Control (2021) (7)
- A molecularly defined insular cortex --> central amygdala circuit mediates conditioned overconsumption of food (2019) (7)
- Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis. (2011) (7)
- Expression of a cholecystokinin precursor-related peptide in vertebrate and invertebrate tissues. (1986) (6)
- Absence of Soluble Leptin Receptor in Plasma from db/db and Other db/db Mice* (1998) (6)
- Mouse microsatellites from a flow-sorted 4:6 Robertsonian chromosome (2004) (5)
- Longitudinal study shows increasing obesity and hyperglycemia in micronesia (2013) (5)
- Erratum: Antidiabetic Effects of IGFBP2, a Leptin-Regulated Gene (DOI:10.1016/j.cmet.2009.11.007) (2010) (5)
- Localization of the cystic fibrosis transmembrane conductance regulator (Cftr) to mouse chromosome 6. (1992) (5)
- Leading the charge in leptin research: an interview with Jeffrey Friedman (2012) (4)
- Mouse chromosome 4 (2004) (4)
- Selection of a Full Agonist Combinatorial Antibody that Rescues Leptin Deficiency In Vivo (2020) (3)
- Gene expression profile induced by leptin in white adipose tissue and liver (1999) (3)
- Limitation of adipose tissue by the number of embryonic progenitor cells (2020) (3)
- Cell Metabolism: Why, and why now? (2005) (3)
- Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues (2021) (3)
- Author response: Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar (2013) (2)
- A Grounded Theory Investigation of Adaptations to Adverse Childhood Experiences (2018) (2)
- Melanocortin 4 receptor stimulation prevents anti-depressant-associated weight gain in mice caused by long-term fluoxetine exposure. (2021) (2)
- How the discovery of microbial opsins led to the development of optogenetics (2021) (2)
- A non-canonical-PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass (2018) (2)
- Pharmacological targeting of glutamatergic neurons within the brainstem for weight reduction (2022) (2)
- FGF21 Counteracts Alcohol Intoxication by Activating the Noradrenergic Nervous System (2023) (2)
- Restriction of food intake by PPP1R17-expressing neurons in the DMH (2021) (2)
- How the discovery of microbial opsins led to the development of optogenetics (2021) (2)
- A limbic circuit selectively linking active escape to food suppression (2019) (1)
- Corrigendum to "Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression"[Mol Metab 4 (2015) 392-405]. (2015) (1)
- Author response: A critical role for mTORC1 in erythropoiesis and anemia (2014) (1)
- Obesity. Brown fat and yellow mice. (1993) (1)
- Lateral septum neurotensin neurons link stress and anorexia (2019) (1)
- Corrigendum: Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles (2015) (1)
- Dynamic processing of hunger and thirst by common mesolimbic neural ensembles (2022) (1)
- Cellular Promoters Incorporated into theAdenovirus Genome: Effects ofViral Regulatory Elements onTranscription Ratesand CellSpecificity ofAlbumin andr3-Globin Promoters (1986) (1)
- on the physical , cytogenetic , and genetic maps of chromosome 7 . The human obese ( OB ) gene : RNA expression pattern and mapping (2007) (1)
- Leptin Rapid Rewiring of Arcuate Nucleus Feeding Circuits (2009) (0)
- Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae Citation Lowe (2009) (0)
- A leptin–BDNF pathway regulating sympathetic innervation of adipose tissue (2020) (0)
- a Weighty Problem (1992) (0)
- CNR1 Regulation of Growth and Glucose Metabolism (2013) (0)
- Mouse Chromosome 4 (2004) (0)
- Db, the receiver for leptine, receiver nucleic acids and its uses. (1997) (0)
- Obesity (OB) peptides capable of modulating body weight of animals, allelic variants, analogs and fragments thereof, derivatives, nucleic acid sequences, vect (1995) (0)
- New Editors, Features and Procedures (1989) (0)
- A conversation with Jeffrey M. Friedman by Ushma S. Neill. (2013) (0)
- Leptin and the homeostatic system regulating body weight (2012) (0)
- Author Correction: Pharmacological targeting of glutamatergic neurons within the brainstem for weight reduction (2022) (0)
- LEPTIN AND THE NEURAL CIRCUIT REGULATING BODY WEIGHT (2000) (0)
- Leptin-Driven Lipolysis is Mediated by Sympathetic Neuro-Adipose Connections. (2018) (0)
- A Developmental Role for Microglial Presenilin 1 in Memory (2021) (0)
- Focus and Highlights of Symposia and Events (2015) (0)
- Leptin receptor db, for this encoding nucleic acids and applications thereof (1997) (0)
- Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity (2019) (0)
- ROLE OF LEPTIN IN ACUTE PANCREATITIS INDUCED BY IL‐12 AND IL‐18: 140 (2004) (0)
- Jeffrey Friedman Receives Bristol-Myers Squibb Award for Metabolic Research (2001) (0)
- FGF21 Counteracts Alcohol Intoxication by Activating Noradrenergic Neurons (2022) (0)
- The weight-regulating agents, and the like nukseiinihapot proteins and their diagnostic and therapeutic uses (1997) (0)
- Leptin and the endocrine control of energy balance (2019) (0)
- Obesity(OB) polypeptides (1995) (0)
- Db leptin receptor, the receptor-encoding nucleic acids and applications thereof (1997) (0)
- Regulation ofN-mycGeneExpression: Useofan Adenovirus Vector ToDemonstrate Posttranscriptio nal Control (1990) (0)
- Cell Metabolism Molecular Markers for Feeding Neural Circuits (0)
- Roles and regulations of dopaminergic pathways in repeated stress-induced emotional changes (2018) (0)
- Author response: Limitation of adipose tissue by the number of embryonic progenitor cells (2020) (0)
- Author response: A limbic circuit selectively links active escape to food suppression (2020) (0)
- Leptin and the Biologic Basis of Obesity (2007) (0)
- Encoding of an engram for food location by satiety-promoting Drd2 hippocampal neurons (2018) (0)
- A United States Patent ( 19 ) 11 Patent Number : 5 , 935 , 810 (2017) (0)
- Douglas Coleman (1931–2014) (2014) (0)
- Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 4. (1993) (0)
- Microbiota-stimulated Interleukin-22 regulates brain neurons and protects against stress-induced anxiety (2022) (0)
- Vector To Demonstrate Posttranscriptional Control (0)
- Phytosterolemia on the island of Kosrae Published, JLR Papers in Press, June 21, 2004. DOI 10.1194/jlr.M400006-JLR200 (2004) (0)
- Modulators of body weight of the corresponding nukleinsaüre and proteins, and diagnostic and therapeutic uses thereof (1995) (0)
- A Molecularly Defined Insular to Central Amygdala Circuit Controls Conditioned Overconsumption (2020) (0)
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