Jeffrey V. Ravetch

Jeffrey V. Ravetch's AcademicInfluence.com Rankings

Jeffrey V. Ravetch

Biology

#1853

World Rank

#3006

Historical Rank

#875

USA Rank

Immunology

#82

World Rank

#88

Historical Rank

#30

USA Rank

biology Degrees

Download Badge

Biology

Jeffrey V. Ravetch's Degrees

Bachelors Biochemistry University of California, Berkeley
PhD Biochemistry University of California, Berkeley

Why Is Jeffrey V. Ravetch Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Jeffrey Victor Ravetch is a professor and head of the Laboratory of Molecular Genetics and Immunology at The Rockefeller University. Background and training Ravetch earned his B.S. degree at Yale University in 1973 in molecular biophysics and biochemistry working with Donald Crothers on the thermodynamic and kinetic properties of synthetic oligoribonucleotides. He received a Ph.D. from The Rockefeller University in 1978 in bacterial genetics working in the laboratory of Norton Zinder and Peter Model in the Laboratory of Genetics at Rockefeller and an M.D. from Cornell University Medical School in 1979. He completed postdoctoral studies at the National Institutes of Health with Philip Leder, where he identified and characterized the genes for human antibodies and the DNA elements involved in switch recombination. From 1982 to 1996 Dr. Ravetch was a member of the faculty of Memorial Sloan-Kettering Cancer Center and Cornell Medical College. Currently, Ravetch is the Theresa and Eugene M. Lang Professor in the Leonard Wagner Laboratory of Molecular Genetics and Immunology at The Rockefeller University.

(See a Problem?)

Jeffrey V. Ravetch's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets (2000) (2840)
Fcγ receptors as regulators of immune responses (2008) (2177)
Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo (2001) (1984)
Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation (2006) (1618)
Fcgamma receptors as regulators of immune responses. (2008) (1418)
Immune inhibitory receptors. (2000) (1343)
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma (2013) (1191)
Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor. (2001) (1038)
Fcγ Receptors: Old Friends and New Family Members (2006) (1012)
Divergent Immunoglobulin G Subclass Activity Through Selective Fc Receptor Binding (2005) (979)
FcR γ chain deletion results in pleiotrophic effector cell defects (1994) (956)
γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins (1985) (940)
Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes (1981) (914)
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals (2009) (869)
Augmented humoral and anaphylactic responses in FcγRII-deficient mice (1996) (809)
Fc receptors. (1997) (790)
Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis. (2000) (787)
Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FeγRIIB (1996) (765)
Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc (2008) (762)
The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody Immunotherapy (2004) (677)
Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo (2014) (648)
Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. (1998) (641)
FcγRIV : A novel FcR with distinct IgG subclass specificity (2005) (620)
Biochemical characterization of a gamma interferon-inducible cytokine (IP-10) (1987) (618)
Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins. (1983) (596)
Absence of marginal zone B cells in Pyk-2–deficient mice defines their role in the humoral response (2000) (588)
Fcgamma receptors: old friends and new family members. (2006) (568)
Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells. (1981) (567)
Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions (1989) (556)
A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling (1994) (550)
Deletion of SHIP or SHP-1 Reveals Two Distinct Pathways for Inhibitory Signaling (1997) (528)
Anti-inflammatory actions of intravenous immunoglobulin. (2008) (520)
Identification of a receptor required for the anti-inflammatory activity of IVIG (2008) (501)
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice (2012) (493)
Intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway (2011) (490)
Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance (2003) (471)
SHIP modulates immune receptor responses by regulating membrane association of Btk. (1998) (419)
Broadly Neutralizing Anti-HIV-1 Antibodies Require Fc Effector Functions for In Vivo Activity (2014) (412)
Type I and type II Fc receptors regulate innate and adaptive immunity (2014) (408)
Modulation of Immune Complex–induced Inflammation In Vivo by the Coordinate Expression of Activation and Inhibitory Fc Receptors (1999) (407)
Divergent roles for Fc receptors and complement in vivo. (1998) (401)
Fc-receptors as regulators of immunity. (2007) (397)
Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis. (2016) (396)
FcR gamma chain deletion results in pleiotrophic effector cell defects. (1994) (394)
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation (2010) (392)
Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions. (2005) (384)
Inducing Tumor Immunity through the Selective Engagement of Activating Fcγ Receptors on Dendritic Cells (2002) (382)
Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis. (1997) (380)
Fc receptors: Rubor redux (1994) (366)
FcgammaRIV: a novel FcR with distinct IgG subclass specificity. (2005) (348)
Fc receptors are required in passive and active immunity to melanoma. (1998) (346)
Deletion of Fcγ Receptor IIB Renders H-2b Mice Susceptible to Collagen-induced Arthritis (1999) (342)
Structural heterogeneity and functional domains of murine immunoglobulin G Fc receptors. (1986) (332)
Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade. (1994) (323)
Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. (2003) (321)
Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice (2014) (321)
Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. (1996) (316)
Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection. (2016) (306)
Inhibitory Fcγ Receptor Engagement Drives Adjuvant and Anti-Tumor Activities of Agonistic CD40 Antibodies (2011) (300)
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors (2017) (292)
Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes (1989) (288)
Enhanced clearance of HIV-1–infected cells by broadly neutralizing antibodies against HIV-1 in vivo (2016) (287)
A Novel Role for the IgG Fc Glycan: The Anti-inflammatory Activity of Sialylated IgG Fcs (2010) (285)
Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination. (1990) (284)
Antibody‐mediated modulation of immune responses (2010) (282)
Genetic Modifiers of Systemic Lupus Erythematosus in FcγRIIB−/− Mice (2002) (270)
Cytotoxic antibodies trigger inflammation through Fc receptors. (1995) (265)
The inhibitory Fcγ receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells (2005) (263)
Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells. (2005) (261)
The antiinflammatory activity of IgG: the intravenous IgG paradox (2007) (260)
Macrophages Control the Retention and Trafficking of B Lymphocytes in the Splenic Marginal Zone (2003) (256)
Antibodies, Fc receptors and cancer. (2007) (254)
Selective dysregulation of the FcγIIB receptor on memory B cells in SLE (2006) (248)
A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling (1994) (248)
Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors (2006) (245)
The role of IgG Fc receptors in antibody-dependent enhancement (2020) (242)
Inhibitory pathways triggered by ITIM-containing receptors. (1999) (240)
Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity (2007) (237)
Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo (2020) (236)
FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis. (2015) (236)
Peripheral Aβ subspecies as risk biomarkers of Alzheimer's disease (2008) (234)
IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity (2017) (233)
Mouse model recapitulating human Fcγ receptor structural and functional diversity (2012) (232)
Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB. (1996) (230)
Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease (2009) (230)
Modulating IgG effector function by Fc glycan engineering (2017) (230)
Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect (2015) (224)
SHIP Recruitment Attenuates FcγRIIB-Induced B Cell Apoptosis (1999) (218)
Immunoglobulin G–mediated Inflammatory Responses Develop Normally in Complement-deficient Mice (1996) (218)
Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction. (2006) (216)
CD4+ T Cell–mediated Granulomatous Pathology in Schistosomiasis Is Downregulated by a B Cell–dependent Mechanism Requiring Fc Receptor Signaling (1998) (205)
TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE (2006) (201)
Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: a novel murine model for autoimmune glomerular basement membrane disease. (2000) (195)
Intravenous immunoglobulins – understanding properties and mechanisms (2009) (194)
Absence of Fc epsilonRI alpha chain results in upregulation of Fc gammaRIII-dependent mast cell degranulation and anaphylaxis. Evidence of competition between Fc epsilonRI and Fc gammaRIII for limiting amounts of FcR beta and gamma chains. (1997) (193)
Modulation of Immunoglobulin (Ig)E-mediated Systemic Anaphylaxis by Low-Affinity Fc Receptors for IgG (1999) (192)
General mechanism for modulating immunoglobulin effector function (2013) (188)
Human immunoglobulin D segments encoded in tandem multigenic families (1981) (187)
Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain (1992) (182)
Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3. (1993) (174)
TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE. (2006) (172)
FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo (2010) (172)
A dominant role for mast cell Fc receptors in the Arthus reaction. (1996) (171)
Aglycosylated immunoglobulin G1 variants productively engage activating Fc receptors (2008) (170)
Novel roles for the IgG Fc glycan (2012) (170)
In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner (2008) (167)
Fcγ Receptor IIB on Follicular Dendritic Cells Regulates the B Cell Recall Response1 (2000) (167)
Biochemical Nature and Cellular Distribution of the Paired Immunoglobulin-like Receptors, PIR-A and PIR-B (1999) (165)
Characterization of the promoter of the human gene encoding the high-affinity IgG receptor: transcriptional induction by gamma-interferon is mediated through common DNA response elements. (1991) (165)
A single amino acid in the glycosyl phosphatidylinositol attachment domain determines the membrane topology of FcγRIII (1989) (164)
Large deletions result from breakage and healing of P. falciparum chromosomes (1988) (163)
Fc receptors. (1991) (163)
Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis. (1998) (163)
A chromosomal rearrangement in a P. falciparum histidine-rich protein gene is associated with the knobless phenotype (1986) (156)
A subunit common to an IgG Fc receptor and the T-cell receptor mediates assembly through different interactions. (1991) (152)
Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia. (2005) (149)
Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy (2015) (148)
Signaling by Antibodies: Recent Progress. (2017) (144)
Molecular and biochemical characterization of a novel gamma-interferon-inducible protein. (1988) (141)
FcγRs in health and disease. (2011) (135)
Fcγ Receptor Function and the Design of Vaccination Strategies. (2017) (135)
Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program (2007) (131)
Genomic characterization of a gamma-interferon-inducible gene (IP-10) and identification of an interferon-inducible hypersensitive site (1987) (128)
Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus (2007) (127)
Structural characterization of anti-inflammatory immunoglobulin G Fc proteins. (2014) (126)
The role of Fc–FcγR interactions in IgG-mediated microbial neutralization (2015) (125)
B Cell Antigen Receptor Engagement Inhibits Stromal Cell–derived Factor (SDF)-1α Chemotaxis and Promotes Protein Kinase C (PKC)-induced Internalization of CXCR4 (1999) (123)
Cloning and characterization of a mouse cysteine proteinase. (1986) (122)
Restoration of Tolerance in Lupus by Targeted Inhibitory Receptor Expression (2005) (120)
Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement. (2016) (119)
Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency (2016) (119)
Function and regulation of a murine macrophage-specific IgG Fc receptor, Fc gamma R-alpha (1988) (119)
Opposing effects of Toll-like receptor stimulation induce autoimmunity or tolerance. (2007) (119)
Physical and functional association of p56lck with Fc gamma RIIIA (CD16) in natural killer cells (1993) (112)
Endoglycosidase treatment abrogates IgG arthritogenicity: Importance of IgG glycosylation in arthritis (2007) (109)
Molecular Determinants of the Myristoyl-electrostatic Switch of MARCKS* (1996) (108)
Effective therapy for a murine model of adult T-cell leukemia with the humanized anti-CD52 monoclonal antibody, Campath-1H. (2003) (104)
Amplified follicular immune complex deposition in mice lacking the Fc receptor gamma-chain does not alter maturation of the B cell response. (1997) (104)
A requirement for FcγR in antibody-mediated bacterial toxin neutralization (2010) (103)
Fc-Receptor Interactions Regulate Both Cytotoxic and Immunomodulatory Therapeutic Antibody Effector Functions (2015) (103)
Fc gamma receptor IIB on follicular dendritic cells regulates the B cell recall response. (2000) (102)
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2 (2020) (102)
Transcription mapping of a 100 kb locus of Plasmodium falciparum identifies an intergenic region in which transcription terminates and reinitiates. (1992) (99)
Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes. (2004) (98)
Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement (2012) (97)
Human interferon-inducible protein 10: expression and purification of recombinant protein demonstrate inhibition of early human hematopoietic progenitors (1993) (97)
Antitumor activities of agonistic anti-TNFR antibodies require differential FcγRIIB coengagement in vivo (2013) (96)
Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program (2007) (95)
High Pathogenic Potential of Low-Affinity Autoantibodies in Experimental Autoimmune Hemolytic Anemia (1999) (92)
Antibody-mediated Modulation of Cryptococcus neoformans Infection Is Dependent on Distinct Fc Receptor Functions and IgG Subclasses (1998) (92)
Fcγ receptor pathways during active and passive immunization (2015) (90)
FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis. (2015) (90)
Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells. (1987) (90)
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2 (2020) (87)
Primary structure and subcellular localization of the knob-associated histidine-rich protein of Plasmodium falciparum. (1987) (86)
IL-15 enhanced antibody-dependent cellular cytotoxicity mediated by NK cells and macrophages (2018) (85)
Translating basic mechanisms of IgG effector activity into next generation cancer therapies. (2012) (84)
Role of the inositol phosphatase SHIP in B cell receptor-induced Ca2+ oscillatory response. (1998) (83)
Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases (2008) (82)
Disruption of cell-cell adhesion enhances antibody-dependent cellular cytotoxicity: implications for antibody-based therapeutics of cancer. (2002) (82)
Crucial Role of Aspartic Acid at Position 265 in the CH2 Domain for Murine IgG2a and IgG2b Fc-Associated Effector Functions1 (2008) (82)
Differential Contribution of Three Activating IgG Fc Receptors (FcγRI, FcγRIII, and FcγRIV) to IgG2a- and IgG2b-Induced Autoimmune Hemolytic Anemia in Mice1 (2008) (80)
Myelin protein zero gene mutated in Charcot-Marie-tooth type 1B patients. (1993) (80)
Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs (2015) (80)
Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy (2021) (79)
Effective therapy for a murine model of adult T-cell leukemia with the humanized anti-CD2 monoclonal antibody, MEDI-507. (2003) (78)
SHIP recruitment attenuates Fc gamma RIIB-induced B cell apoptosis. (1999) (77)
The beta subunit of the Fc epsilon RI is associated with the Fc gamma RIII on mast cells (1992) (77)
Isolation of the gene for a glycophorin-binding protein implicated in erythrocyte invasion by a malaria parasite. (1985) (76)
Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection (2020) (76)
A tandemly repeated sequence determines the binding domain for an erythrocyte receptor binding protein of P. falciparum (1986) (76)
Redundant and alternative roles for activating Fc receptors and complement in an antibody-dependent model of autoimmune vitiligo. (2002) (75)
Analyzing antibody-Fc-receptor interactions. (2008) (74)
The Role and Function of Fcγ Receptors on Myeloid Cells. (2016) (71)
Reconstitution of human Fc gamma RIII cell type specificity in transgenic mice (1996) (71)
A mouse model for HIV-1 entry (2012) (71)
Inversion in the H–2 complex of t-haplotypes in mice (1983) (71)
Functional diversification of IgGs through Fc glycosylation. (2019) (70)
Cloning and molecular characterization of the murine macrophage "68-kDa" protein kinase C substrate and its regulation by bacterial lipopolysaccharide. (1991) (70)
A full complement of receptors in immune complex diseases. (2002) (69)
The polymorphic subtelomeric regions of Plasmodium falciparum chromosomes contain arrays of repetitive sequence elements. (1994) (69)
Murine natural killer cells express functional Fc gamma receptor II encoded by the Fc gamma R alpha gene (1989) (69)
Activating Fc Receptors Are Required for Antitumor Efficacy of the Antibodies Directed toward CD25 in a Murine Model of Adult T-Cell Leukemia (2004) (68)
Diversification of IgG effector functions (2017) (68)
Plasmodium: control of gene expression in malaria parasites. (1993) (67)
Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections (2018) (65)
Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes. (1980) (65)
New nomenclature for Fc receptor–like molecules (2006) (64)
A sequence element associated with the Plasmodium falciparum KAHRP gene is the site of developmentally regulated protein-DNA interactions. (1992) (63)
Fcγ Receptor Iib–Deficient Mice Develop Goodpasture's Syndrome upon Immunization with Type IV Collagen (2000) (63)
Primary structure and genomic organization of the histidine-rich protein of the malaria parasite Plasmodium lophurae (1984) (63)
Transcriptional differences in polymorphic and conserved domains of a complete cloned P. falciparum chromosome (1993) (62)
Targeting MARCO and IL37R on Immunosuppressive Macrophages in Lung Cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function (2020) (61)
Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody (2018) (60)
Experimental Antibody Therapy of Liver Metastases Reveals Functional Redundancy between FcγRI and FcγRIV1 (2008) (59)
Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells (2020) (57)
FcγRIIB Deficiency Leads to Autoimmunity and a Defective Response to Apoptosis in Mrl-MpJ Mice1 (2008) (57)
Current status of the Plasmodium falciparum genome project. (1996) (56)
Inhibitory Fcγ Receptor Is Required for the Maintenance of Tolerance through Distinct Mechanisms (2014) (52)
Multiple immunoglobulin switch region homologies outside the heavy chain constant region locus (1981) (52)
Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity. (2014) (52)
Evidence for the participation of the Ssp-3 antigen in the invasion of nonphagocytic mammalian cells by Trypanosoma cruzi (1992) (49)
Lack of antibody affinity maturation due to poor Toll stimulation led to enhanced RSV disease (2008) (49)
T Cell Development in Mice Lacking All T Cell Receptor ζ Family Members (ζ, η, and FcεRIγ) (1998) (49)
Fcgamma receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice. (2009) (48)
Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b −/− Pdcd1 −/− mice (2005) (47)
Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity (2018) (46)
DC subset–specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo (2017) (46)
A DNA insertion/deletion necessitates an aberrant RNA splice accounting for a mu heavy chain disease protein. (1986) (45)
FcγRIII (CD16) on human macrophages is a functional product of the FcγRIII‐2 gene (1991) (45)
Chromatin structure determines the sites of chromosome breakages in Plasmodium falciparum. (1994) (42)
T Cell Studies in a Peptide-Induced Model of Systemic Lupus Erythematosus (2001) (42)
Anti‐retroviral antibody FcγR‐mediated effector functions (2017) (42)
Complement Activation and Complement Receptors on Follicular Dendritic Cells Are Critical for the Function of a Targeted Adjuvant (2011) (42)
Antibody fucosylation predicts disease severity in secondary dengue infection (2021) (41)
Characterization of yeast artificial chromosomes from Plasmodium falciparum: construction of a stable, representative library and cloning of telomeric DNA fragments. (1992) (41)
Differential requirements for FcγR engagement by protective antibodies against Ebola virus (2019) (41)
Thermodynamic and kinetic properties of short RNA helices: the oligomer sequence AnGCUn. (1974) (40)
FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies (2020) (40)
FcγRIII and FcγRIV Are Indispensable for Acute Glomerular Inflammation Induced by Switch Variant Monoclonal Antibodies1 (2008) (39)
Synergy between an antibody and CD8+ cells in eliminating an established tumor (1997) (39)
Increasing the breadth and potency of response to the seasonal influenza virus vaccine by immune complex immunization (2017) (38)
Designer Cytokines: Targeting Actions to Cells of Choice (1995) (38)
Deletion of the fcgamma receptor IIb in thymic stromal lymphopoietin transgenic mice aggravates membranoproliferative glomerulonephritis. (2003) (38)
Siglecs-7/9 function as inhibitory immune checkpoints in vivo and can be targeted to enhance therapeutic antitumor immunity (2021) (34)
A general requirement for FcγRIIB co-engagement of agonistic anti-TNFR antibodies (2012) (33)
Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice. (2008) (31)
Nucleotide sequence of the recognition site for the restriction-modification enzyme of Escherichia coli B. (1978) (31)
Effective therapy for a murine model of human anaplastic large-cell lymphoma with the anti-CD30 monoclonal antibody, HeFi-1, does not require activating Fc receptors. (2006) (30)
Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo (2020) (30)
The Naive B Cell Repertoire Predisposes to Antigen-Induced Systemic Lupus Erythematosus (2003) (29)
humanized mice to study FcγR function. (2014) (28)
Transcriptional and nucleosomal characterization of a subtelomeric gene cluster flanking a site of chromosomal rearrangements in Plasmodium falciparum. (1994) (28)
Phagocytic cells (2007) (27)
Organization of chromosomes in Plasmodium falciparum: a model for generating karyotypic diversity. (1994) (27)
Antibodies targeting sialyl Lewis A mediate tumor clearance through distinct effector pathways. (2019) (26)
Antibody and Antiretroviral Preexposure Prophylaxis Prevent Cervicovaginal HIV-1 Infection in a Transgenic Mouse Model (2013) (26)
Organization of a hybrid between phage f1 and plasmid pSC101. (1979) (26)
In vivo veritas: the surprising roles of Fc receptors in immunity (2010) (26)
Acute inflammation primes myeloid effector cells for anti-inflammatory STAT6 signaling (2013) (25)
Killing some to make way for others (2007) (25)
Molecular Genetic Strategies for the Development of Anti-Malarial Vaccines (1985) (25)
TLR 9 / MyD 88 signaling is required for class switching to pathogenic IgG 2 a and 2 b autoantibodies in SLE (2006) (25)
Atopy and Fc receptors: mutation is the message? (1994) (24)
A and T homopolymeric stretches mediate a DNA inversion in Plasmodium falciparum which results in loss of gene expression (1990) (24)
Immunotherapy and Hyperprogression: Unwanted Outcomes, Unclear Mechanism (2018) (24)
A YAC contig map of Plasmodium falciparum chromosome 4: characterization of a DNA amplification between two recently separated isolates. (1995) (23)
A single amino acid in the glycosyl phosphatidylinositol attachment domain determines the membrane topology of Fc gamma RIII. (1989) (23)
A Critical Role for FcγRIIB in the Induction of Rheumatoid Factors1 (2004) (23)
Immune complexes: not just an innocent bystander in chronic viral infection. (2015) (22)
Chromosomal polymorphisms and gene expression in Plasmodium falciparum. (1989) (21)
Lysibodies are IgG Fc fusions with lysin binding domains targeting Staphylococcus aureus wall carbohydrates for effective phagocytosis (2017) (21)
DNA replication of bacteriophage f1 in vivo. (1979) (21)
Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. (2008) (20)
T lymphocyte development in the absence of Fcϵ receptor Iγ subunit: analysis of thymic‐dependent and independent αβ and γδ pathways (1996) (19)
Immunological responses to influenza vaccination: lessons for improving vaccine efficacy. (2018) (19)
Dendritic cell targeting with Fc-enhanced CD40 antibody agonists induces durable antitumor immunity in humanized mouse models of bladder cancer (2021) (18)
Impact of a Three Amino Acid Deletion in the CH2 Domain of Murine IgG1 on Fc-Associated Effector Functions1 (2008) (18)
SAR228810: An antiprotofibrillar beta-amyloid antibody designed to reduce risk of amyloid-related imaging abnormalities (ARIA) (2013) (16)
A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques (2020) (16)
Thymic stromal lymphopoietin transgenic mice develop cryoglobulinemia and hepatitis with similarities to human hepatitis C liver disease. (2007) (15)
PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine (2022) (15)
Nucleotide sequences near the origin of replication of bacteriophage f1. (1977) (15)
New tricks for old molecules (1994) (14)
Differential contribution of the FcR gamma chain to the surface expression of the T cell receptor among T cells localized in epithelia: analysis of FcR gamma-deficient mice. (1995) (14)
SAR228810: an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA) (2018) (13)
Fc receptor signaling. (1994) (13)
Engineering Aglycosylated IgG Variants with Wild-Type or Improved Binding Affinity to Human Fc Gamma RIIA and Fc Gamma RIIIAs. (2017) (13)
Site-Selective Chemoenzymatic Modification on the Core Fucose of an Antibody Enhances Its Fcγ Receptor Affinity and ADCC Activity. (2021) (13)
Enhanced clearance of HIV-1-infected cells by anti-HIV-1 broadly neutralizing antibodies in vivo (2016) (12)
Mapping of bacteriophage f1 ribosome binding sites to their cognate genes. (1977) (12)
Isolation and characterisation of the φX174 ribosome binding sites (1977) (11)
Functional consequences of lipid-mediated protein-membrane interactions. (1991) (11)
Intact 3′ end of 16S rRNA is not required for specific mRNA binding (1976) (11)
Fc-engineered antibody therapeutics with improved efficacy against COVID-19 (2021) (11)
Fc receptor genetics and the manipulation of genes in the study of FcR biology (1998) (10)
DNA sequence analysis of the defective interfering particles of bacteriophage f1. (1979) (9)
Four keys to unlock IgG (2021) (9)
Fc gamma RIII (CD16) on human macrophages is a functional product of the Fc gamma RIII-2 gene. (1991) (9)
A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies (2017) (9)
Cutting Edge: Role of the Inositol Phosphatase SHIP in B Cell Receptor- Induced Ca 21 Oscillatory Response 1 (1998) (8)
Reply to Crispin et al.: Molecular model that accounts for the biological and physical properties of sialylated Fc (2013) (8)
Modulation of gene expression during terminal cell differentiation: murine erythroleukemia. (1984) (8)
Immunity Report Fc-Optimized Anti-CD 25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors (2017) (8)
Inhibitory Fcg Receptor Is Required for the Maintenance of Tolerance through Distinct Mechanisms (2014) (8)
One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody-Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling. (2021) (8)
Reply to Bayry et al.: The anti-inflammatory activity of sialylated IgG Fcs (2009) (7)
Activating and Inhibitory Immunoglobulin-like Receptors (2001) (6)
Co-targeting of Adenosine Signaling Pathways for Immunotherapy: Potentiation by Fc Receptor Engagement. (2016) (4)
T lymphocyte development in the absence of Fc epsilon receptor I gamma subunit: analysis of thymic-dependent and independent alpha beta and gamma delta pathways. (1996) (4)
Primary structure and genomic organization of the histidine-rich protein of the malaria parasite Plasmodium lophurae (1985) (4)
Regulation of the humoral immune response: from immunoglobulin genes to regulatory T cell networks. (1983) (4)
Renal transplantation and dyslipidemia: characterization of a population and treatment with diet and low dose lovastatin. (1995) (4)
Attenuated Vaccines for Augmented Immunity. (2017) (3)
Profile of Sérgio Ferreira (2008) (3)
Basic nursing education--what's the buzz? (1982) (3)
SAR228810: an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA) (2018) (3)
Abstract 1332: Interleukin-15 enhances rituximab-dependent cytotoxicity ex vivo and in vivo against a mouse lymphoma expressing human CD20 (2015) (3)
Systemic Lupus Erythematosus T Cell Studies in a Peptide-Induced Model of and Betty Diamond (2001) (2)
Human FcγRIIIa activation on splenic macrophages drives the in vivo pathogenesis of dengue disease (2022) (2)
Profile of Edward L. Miles (2006) (2)
Fc and Complement Receptors (2015) (2)
Fc Mediated Activity of Antibodies: Structural and Functional Diversity (2019) (2)
IgG anti-HA Fc glycoform modulation is predictive of influenza vaccine efficacy (IRC10P.412) (2015) (1)
IgG 2 b Fc-Associated Effector Functions in the CH 2 Domain for Murine IgG 2 a and Crucial Role of Aspartic Acid at Position 265 Nishimura and Shozo Izui (2008) (1)
Insights into the Mechanisms of Antibody-Affinity Maturation and the Generation of the Memory B-Cell Compartment Using Genetically Altered Mice (1998) (1)
Fc g Receptor IIB–deﬁcient Mice Develop Goodpasture’s Syndrome upon Immunization with Type IV Collagen: A Novel Murine Model for Autoimmune Glomerular Basement Membrane Disease (2000) (1)
Mechanism of glycoform specificity and protection against antibody dependent enhancement by an anti-afucosylated IgG nanobody (2023) (1)
Profile of Ronald Levy (2010) (1)
An introduction to urological nursing (2000) (1)
1659 The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody (2004) (1)
Biography of Francisco de la Cruz. (2005) (1)
Therapeutic Applications of Sialylated IVIG IVIG (2015) (1)
CHAPTER 18 – Fc and Complement Receptors (2004) (1)
Profile of Andrew R. Marks. (2006) (1)
Targeting myeloid suppressive cells revives cytotoxic anti-tumor responses in pancreatic cancer (2022) (1)
Synthetic nanobodies as tools to distinguish IgG Fc glycoforms (2022) (1)
Physical and Functional Association of p 56 ta ' with Fc ' yRIIIA ( CD 16 ) in Natural Killer Cells (1993) (1)
Antibody-lectin chimeras for glyco-immune checkpoint blockade (2022) (1)
Profile of F. Stuart Chapin III (2006) (1)
Reconstitution of Human Fc ~ / RIII Cell Type Specificity in Transgenic Mice (2003) (1)
Therapeutic Applications of Sialylated IVIG (2014) (1)
Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection (2020) (0)
Metastases Reveals Functional Redundancy Experimental Antibody Therapy of Liver (2008) (0)
An Fc-Optimized Monoclonal Antibody Against CD32B, the Human Inhibitory Fc-γ Receptor IIB, in the Immunotherapy of B-Cell Malignanacy. (2006) (0)
Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c- Fcgr2b (cid:1) / (cid:1) Pdcd1 (cid:1) / (cid:1) mice (2005) (0)
Chain Results in Upregulation of Fc g RIII-dependent Mast Cell Degranulation and Anaphylaxis Evidence of Competition between Fc e RI and Fc g RIII for Limiting Amounts of FcR b and g Chains (2013) (0)
Crystal structure of a chemoenzymatic glycoengineered disialylated Fc (di-sFc) (2014) (0)
Nucleotide sequence oftherecognition site fortherestriction- modification enzymeofEscherichia coli B (1978) (0)
IL-15 synergizes with CD40 agonist antibodies to induce durable immunity against bladder cancer (2023) (0)
Abstract B28: Improved therapeutic activity of agonistic, human anti-CD40 monoclonal Abs by selective FcγR-engagement (2016) (0)
Profile of Jeffrey Ravetch. Interview by Philip Downey. (2009) (0)
A novel mouse strain optimized for chronic human antibody administration (2022) (0)
Novel Fc receptors mediating the anti-inflammatory properties of IgG (2010) (0)
FcyRIIB is a novel immune checkpoint in the tumor microenvironment limiting activity of Treg-targeting antibodies (2023) (0)
Therapeutic Activity of Ag onistic , Human Anti-CD 40 Monoclonal Antibodies Requires Selective Fc g R Engagement Graphical (2016) (0)
A single amino acid in the glycosyl phosphatidylinositol attachment domain determines the membrane topology of FcγRIII (1990) (0)
D-109 Special lecture: Fc effector functions in the anti-viral response (2016) (0)
G-109 Special lecture: Engineering anti-HIV antibodies for optimal control of HIV infection (2017) (0)
The structural basis for the anti-inflammatory activity of sialylated antibodies (THER5P.822) (2014) (0)
Signal Transduction by Fc ' yRIH ( CD 16 ) Is Mediated through the 3 / Chain By Urs Wirthmueller , Tomohiro Kurosaki (2003) (0)
MAINTAINING SERVICE PROVISION IN AN AGE OF AUSTERITY. (2017) (0)
Profile of Ding-Shinn Chen (2007) (0)
Profile of Jeffrey Ravetch (2009) (0)
Profile of Donald E. Canfield (2011) (0)
Chapter One: Why Frankenstein? (2017) (0)
Chapter Five: Do Students Have a Say in How, or What, They Learn? (2017) (0)
Profile of C. David Allis. (2006) (0)
Meteorites in the Driveway: Rocks frin Heaven (2011) (0)
Profile of Susan N. Coppersmith (2012) (0)
QnAs with Peter H. Gleick (2011) (0)
Chapter Two: Digital Immigrants vs Digital Natives (2017) (0)
Attorneys' Trust Accounts: The Bar's Role in the Preservation of Client Property (1988) (0)
Profile of Roberta L. Rudnick (2012) (0)
Chapter Three: Can Technology Be Too Much of a Good Thing? (2017) (0)
Profile of Ranulfo Romo (2006) (0)
Profile of Akira Tonomura. (2005) (0)
Profile of David Haussler (2008) (0)
Profile of Thure E. Cerling (2010) (0)
Profile of José N. Onuchic (2010) (0)
Immunoregulatory Effects of Intravenous Immunoglobulin: Mechanistic Insights (2004) (0)
Reprogramming Tumor-As sociated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis Graphical Abstract Highlights (2016) (0)
Current Topics in Microbiology and Immunology (1976) (0)
Fc-Associated Effector Functions CH 2 Domain of Murine IgG 1 on Impact of a Three Amino Acid Deletion in the Nishimura (2008) (0)
Current Understanding of Possible Mechanisms of Action and Resistance of Rituximab (2001) (0)
Systematic Evaluation of AML-Associated Antigens Identifies Novel Anti-U5 snRNP200 Therapeutic Antibodies for the Treatment of AML (2022) (0)
Rapid In Vivo Consumption and Ex Vivo Phagocytosis of WASP(−) Platelets. (2007) (0)
IgG2a and 2b autoantibodies in SLE (2006) (0)
Antibody therapy (SY5-2) Chairpersons: Norihiro Nishimoto, Jeffrey V. Ravetch (2010) (0)
Depletion of regulatory T cells results in the loss of peripheral tolerance and the development of autoimmune disease . Fc γ receptors as regulators of immune responses (2007) (0)
Genetic Modiﬁers of Systemic Lupus Erythematosus in Fc (cid:2) RIIB (cid:3) / (cid:3) Mice (2002) (0)
Molecular Genetic Analysis of Parasite Survival in P. falciparum Malaria (1993) (0)
Organization and Expression of Plasmodial Genes Required for Erythrocyte Invasion (1989) (0)
Yoshikatsu Kaneko , Resulting from Fc Sialylation Anti-Inflammatory Activity of Immunoglobulin (2009) (0)
AdjuvantCritical for the Function of a Targeted Receptors on Follicular Dendritic Cells Are Complement Activation and Complement (2011) (0)
Immunology. New tricks for old molecules. (1994) (0)
THE CIS FAHEY/ROSE FOUNDERS LECTURE (2013) (0)
A general mechanism for anti-tumor therapy based on Fc receptor engagement (2008) (0)
The delivery of antigens to dendritic cells is a potent futureoption for anti-tumor therapies (2017) (0)
Antigen targeting of Fc-receptors induces strong T cell responses in vivo independent of ITAM signaling but dependent on dendritic cell subsets (2018) (0)
Primary structure and subcellular localization of the knob-associated histidine-rich protein of Plasmodium falciparum (malaria/cDNA/tandem (0)
Protection by a broadly neutralizing monoclonal antibody to pandemic Influenza requires selective Fc receptor engagement (P4216) (2013) (0)
Abstract B179: Enhancing intratumoural Treg depletion through antibody engineering and analysis of the checkpoint landscape of mouse and human cancers (2016) (0)
364 Antigen targeting of Fc-receptors induces strong T cell responses in vivo independent of ITAM signalling (2016) (0)
CTIM-23. DOSE ESCALATION TRIAL OF FC-ENGINEERED ANTI-CD40 MONOCLONAL ANTIBODY (2141-V11) ADMINISTERED INTRATUMORALLY WITH D2C7-IT VIA CONVECTION-ENHANCED DELIVERY (CED) FOR RECURRENT MALIGNANT GLIOMAS (RMGS) (2022) (0)
496 Toxicity of an Fc engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable anti-tumor immunity in patients (2021) (0)
HUMAN IMMUNOGLOBULIN GENES: THE ONTOGENY OF SOMATIC REARRANGEMENTS (1981) (0)
DifferentialFc-ReceptorEngagementDrivesanAnti- tumor Vaccinal Effect (2015) (0)
Antibody targeting of tumor associated macrophages in lung cancer remodel the tumor microenvironment and revives immune targeting of tumor cells (2019) (0)
Modulation d'anticorps agonistes anti-tnfr (2011) (0)
Sialylation Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc (2013) (0)
720 Targeting MARCO and IL-37R on anti-inflammatory macrophages in lung cancer blocks regulatory T cells and shift balance to support cytotoxic lymphocyte function (2020) (0)
Systemic Lupus Erythematosus T Cell Studies in a Peptide-Induced Model of (2017) (0)
Results Reverse Passive Arthus Reactions , A Type III Inflammatory Response , Develop Normally in Complement-Deficient Mice (1996) (0)
Closing the circle. Jeffrey V. Ravetch, M.D., Ph.D. Interviewed by Lynne Lederman. (2008) (0)
Fc g Rs Modulate the Anti-t umor Activity of Antibodies Targeting the PD-1 / PD-L 1 Axis Graphical Abstract Highlights (2015) (0)
The / 3 Subunit of the FceRI Is Associated with the Fc 3 ~ RIII on Mast Cells By Tomohiro Kurosaki (2003) (0)
Correction (2002) (0)
IG GF C R ECEPTORS (2001) (0)
Preview : Published ahead of advance online publication A new mouse expressing human Fc c receptors to better predict therapeutic efficacy of human anti-cancer antibodies (2017) (0)

This paper list is powered by the following services:

Other Resources About Jeffrey V. Ravetch

en.wikipedia.org

What Schools Are Affiliated With Jeffrey V. Ravetch?

Jeffrey V. Ravetch is affiliated with the following schools:

Jeffrey V. Ravetch's Academic­Influence.com Rankings