Jennifer Gommerman

Jennifer Gommerman's AcademicInfluence.com Rankings

Jennifer Gommerman

Biology

#15098

World Rank

#19011

Historical Rank

Immunology

#1042

World Rank

#1068

Historical Rank

biology Degrees

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Biology

Why Is Jennifer Gommerman Influential?

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According to Wikipedia, Jennifer Lynn Gommerman is a Canadian immunologist. She is a Tier 1 Canada Research Chair in Tissue-Specific Immunity at the University of Toronto. Gommerman has been examining the role of B lymphocytes in Multiple Sclerosis patients and in animal models of MS. She also studies the antibody response to SARS-CoV-2 in saliva samples from patients with COVID-19.

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Jennifer Gommerman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway (2001) (1128)
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients (2020) (580)
Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. (2011) (427)
Notch2-dependent classical dendritic cells orchestrate intestinal immunity against attaching and effacing bacterial pathogens (2013) (358)
Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy (2015) (315)
Lymphotoxin/LIGHT, lymphoid microenvironments and autoimmune disease (2003) (313)
Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10 (2019) (208)
Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy. (2011) (206)
Nod2-Dependent Th2 Polarization of Antigen-Specific Immunity1 (2008) (182)
Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut (2011) (178)
A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis (2012) (163)
B cell depletion therapies in autoimmune disease: advances and mechanistic insights (2020) (160)
A simple protein-based surrogate neutralization assay for SARS-CoV-2 (2020) (147)
Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation. (2015) (143)
Targeted Deletion of fgl2 Leads to Impaired Regulatory T Cell Activity and Development of Autoimmune Glomerulonephritis1 (2008) (141)
B Cells in the Multiple Sclerosis Central Nervous System: Trafficking and Contribution to CNS-Compartmentalized Inflammation (2015) (115)
Fine-tuning of dendritic cell biology by the TNF superfamily (2012) (109)
A Role for CD21/CD35 and CD19 in Responses to Acute Septic Peritonitis: A Potential Mechanism for Mast Cell Activation1 (2000) (102)
Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis (2017) (100)
Gut microbiota–specific IgA+ B cells traffic to the CNS in active multiple sclerosis (2020) (95)
AID constrains germinal center size by rendering B cells susceptible to apoptosis. (2009) (93)
Tim-3 Negatively Regulates Cytotoxicity in Exhausted CD8+ T Cells in HIV Infection (2012) (90)
Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis (2016) (89)
Re-thinking the functions of IgA+ plasma cells (2014) (84)
Nuclear factor-κB1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells (2011) (82)
A Novel MicroRNA-132-Surtuin-1 Axis Underlies Aberrant B-cell Cytokine Regulation in Patients with Relapsing-Remitting Multiple Sclerosis (2014) (80)
Development of nephritis but not sialadenitis in autoimmune‐prone BAFF transgenic mice lacking marginal zone B cells (2006) (78)
Systemic and mucosal IgA responses are variably induced in response to SARS-CoV-2 mRNA vaccination and are associated with protection against subsequent infection (2022) (76)
The SAGA Deubiquitination Module Promotes DNA Repair and Class Switch Recombination through ATM and DNAPK-Mediated γH2AX Formation. (2016) (74)
Meningeal Tertiary Lymphoid Tissues and Multiple Sclerosis: A Gathering Place for Diverse Types of Immune Cells during CNS Autoimmunity (2016) (73)
Expression of lymphotoxin-αβ on antigen-specific T cells is required for DC function (2007) (71)
Differential stimulation of c-Kit mutants by membrane-bound and soluble Steel Factor correlates with leukemic potential. (2000) (71)
A role for surface lymphotoxin in experimental autoimmune encephalomyelitis independent of LIGHT. (2003) (71)
BAFF induces a hyper-IgA syndrome in the intestinal lamina propria concomitant with IgA deposition in the kidney independent of LIGHT. (2006) (69)
Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway. (2002) (68)
The 3BP2 Adapter Protein Is Required for Optimal B-Cell Activation and Thymus-Independent Type 2 Humoral Response (2007) (64)
Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets (2009) (63)
Protection from apoptosis by steel factor but not interleukin-3 is reversed through blockade of calcium influx. (1998) (62)
Three-Dimensional Imaging of Transparent Tissues via Metal Nanoparticle Labeling. (2017) (52)
Asthma, Type 1 and Type 2 Diabetes Mellitus, and Inflammatory Bowel Disease amongst South Asian Immigrants to Canada and Their Children: A Population-Based Cohort Study (2015) (50)
Phosphatidylinositol 3-Kinase and Ca2+ Influx Dependence for Ligand-stimulated Internalization of the c-Kit Receptor* (1997) (49)
Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry (2019) (47)
An in vitro model of innate lymphoid cell function and differentiation (2014) (45)
HIV Acquisition Is Associated with Increased Antimicrobial Peptides and Reduced HIV Neutralizing IgA in the Foreskin Prepuce of Uncircumcised Men (2014) (45)
Dendritic Cell Subsets in Intestinal Immunity and Inflammation (2020) (44)
Dynamic accumulation of plasmacytoid dendritic cells in lymph nodes is regulated by interferon-beta. (2009) (43)
Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10 (2019) (41)
The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining (2018) (39)
AID mutates a non-immunoglobulin transgene independent of chromosomal position. (2007) (39)
Evidence for sustained mucosal and systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients (2020) (38)
A Sphingosine-1-Phosphate Receptor 1-Directed Agonist Reduces Central Nervous System Inflammation in a Plasmacytoid Dendritic Cell-Dependent Manner (2012) (37)
Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity (2018) (36)
Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis (2018) (35)
Neutralizing antibody responses to SARS-CoV-2 variants in vaccinated Ontario long-term care home residents and workers (2021) (34)
ICOS, CD40, and Lymphotoxin β Receptors Signal Sequentially and Interdependently to Initiate a Germinal Center Reaction1 (2008) (33)
Activated leukocyte cell adhesion molecule regulates B lymphocyte migration across central nervous system barriers (2019) (33)
Substrain Differences Reveal Novel Disease-Modifying Gene Candidates That Alter the Clinical Course of a Rodent Model of Multiple Sclerosis (2010) (31)
AID-Expressing Germinal Center B Cells Cluster Normally within Lymph Node Follicles in the Absence of FDC-M1+ CD35+ Follicular Dendritic Cells but Dissipate Prematurely (2013) (30)
LTβR signaling in dendritic cells induces a type I IFN response that is required for optimal clonal expansion of CD8+ T cells (2011) (30)
Intestinal Batf3-dependent dendritic cells are required for optimal antiviral T-cell responses in adult and neonatal mice (2016) (30)
The lymphotoxin pathway (2006) (29)
Antibody-Independent Function of Human B Cells Contributes to Antifungal T Cell Responses (2017) (29)
LIGHT is dispensable for CD4+ and CD8+ T cell and antibody responses to influenza A virus in mice. (2006) (29)
The Lymphotoxin Network: orchestrating a type I interferon response to optimize adaptive immunity. (2014) (28)
LTβR and CD40: working together in dendritic cells to optimize immune responses (2011) (26)
Negative selection of B lymphocytes: a novel role for innate immunity (2000) (25)
The Regulation of Immune Responses by DC Derived Type I IFN (2013) (23)
Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection (2015) (22)
Stromal Cell Niches in the Inflamed Central Nervous System (2017) (22)
Unusual timing of CD127 expression by mouse uterine natural killer cells (2012) (22)
Complement-associated loss of CA2 inhibitory synapses in the demyelinated hippocampus impairs memory (2021) (21)
The Ins and Outs of Central Nervous System Inflammation-Lessons Learned from Multiple Sclerosis. (2021) (21)
The LIGHT and DARC sides of herpesvirus entry mediator. (2005) (21)
Early-life programming of mesenteric lymph node stromal cell identity by the lymphotoxin pathway regulates adult mucosal immunity (2019) (21)
Siponimod therapy implicates Th17 cells in a preclinical model of subpial cortical injury. (2019) (21)
Cytokine/stromal cell networks and lymphoid tissue environments. (2011) (19)
A TNF-α–CCL20–CCR6 Axis Regulates Nod1-Induced B Cell Responses (2014) (18)
Plasmacytoid dendritic cells and autoimmune inflammation (2014) (17)
A mucosal antibody response is induced by intra-muscular SARS-CoV-2 mRNA vaccination (2021) (16)
Guardians of the oral and nasopharyngeal galaxy: IgA and protection against SARS‐CoV‐2 infection (2022) (15)
An “Outside-In” and “Inside-Out” Consideration of Complement in the Multiple Sclerosis Brain: Lessons From Development and Neurodegenerative Diseases (2021) (15)
Intramuscular SARS-CoV-2 vaccines elicit varying degrees of plasma and salivary antibody responses as compared to natural infection (2021) (15)
Lymphotoxin-sensitive microenvironments in homeostasis and inflammation (2012) (14)
AID and Caspase 8 Shape the Germinal Center Response through Apoptosis (2013) (14)
Antibodies That Block or Activate Mouse B Cell Activating Factor of the Tumor Necrosis Factor (TNF) Family (BAFF), Respectively, Induce B Cell Depletion or B Cell Hyperplasia* (2016) (14)
B-Cell Deficiency Lowers Blood Pressure in Mice (2019) (14)
Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in Aicda−/− and Ung−/− Mice (2018) (14)
Plasma Cells: From Cytokine Production to Regulation in Experimental Autoimmune Encephalomyelitis. (2020) (13)
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in patients with COVID-19 (2021) (13)
Fantastic IgA plasma cells and where to find them (2021) (13)
Faculty Opinions recommendation of Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity. (2019) (12)
A simple protein-based SARS-CoV-2 surrogate neutralization assay (2020) (12)
Secondary B Cell Receptor Diversification Is Necessary for T Cell Mediated Neuro-Inflammation during Experimental Autoimmune Encephalomyelitis (2013) (12)
The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates (2020) (11)
Regulation of neuroinflammation by B cells and plasma cells (2020) (11)
Hematopoietic LTβR deficiency results in skewed T cell cytokine profiles during a mucosal viral infection (2016) (10)
Homeodomain-Interacting Protein Kinase (HIPK)-1 Is Required for Splenic B Cell Homeostasis and Optimal T-Independent Type 2 Humoral Response (2012) (9)
The Impact of Migration on the Gut Metagenome of South Asian Canadians (2021) (9)
B cells in MS: Why, where and how? (2012) (9)
Persistence of T Cell and Antibody Responses to SARS-CoV-2 Up to 9 Months after Symptom Onset (2021) (8)
A Lymphotoxin/Type I IFN Axis Programs CD8+ T Cells To Infiltrate a Self-Tissue and Propagate Immunopathology (2015) (8)
The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates (2020) (7)
NLRC5 deficiency has a moderate impact on immunodominant CD8+ T‐cell responses during rotavirus infection of adult mice (2019) (7)
Generational Patterns of Asthma Incidence among Immigrants to Canada over Two Decades. A Population‐based Cohort Study (2019) (7)
Stromal Cell–Mediated Coordination of Immune Cell Recruitment, Retention, and Function in Brain-Adjacent Regions (2021) (7)
Accumulation of meningeal lymphocytes correlates with white matter lesion activity in progressive multiple sclerosis (2022) (7)
Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis (2019) (6)
A role for the lymphotoxin/LIGHT pathway in T-cell mediated autoimmunity and infectious disease (2004) (5)
Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses (2022) (5)
Antigen-Specific Immunity Nod 2-Dependent Th 2 Polarization of and (2008) (4)
Creation of mixed bone marrow chimeras with appropriate controls (2011) (4)
The lymphotoxin pathway as a novel regulator of dendritic cell function. (2011) (4)
c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells. (2019) (3)
The Impact of IgA and the Microbiota on CNS Disease (2021) (3)
The Role of the BAFF and Lymphotoxin Pathways in B Cell Biology (2015) (3)
The microbiome and IgA nephropathy (2021) (3)
LIGHT is dispensable for CD 4 1 and CD 8 1 T cell and antibody responses to influenza A virus in mice (2006) (2)
Ku-gaa-gii pimitizi-win, the COVID-19 cohort study of people experiencing homelessness in Toronto, Canada: a study protocol (2022) (2)
Age-related changes in multiple sclerosis and experimental autoimmune encephalomyelitis. (2022) (2)
LT{beta}R signaling in Dendritic Cells induces a Type I IFN response that is required for optimal clonal expansion of CD8+ T cells (2011) (1)
Patient education: the key to a successful practice in turbulent times. (1995) (1)
351 Differential Requirement of MALT1 for BAFF-induced Outcomes in B Cell Subsets (2008) (1)
The CNS barriers differentially regulate the migration of B cells (2014) (1)
Lymphotoxin is critically required for the presence of IgA‐promoting iNOS+ DCs in the intestinal lamina propria (2008) (1)
Impact of B cell-depletion on plasma cells in a pre-clinical model of meningeal inflammation and subpial demyelination (2021) (1)
The protozoan commensal Tritrichomonas musculis is a natural adjuvant for mucosal IgA (2022) (1)
Accumulation of meningeal lymphocytes, but not myeloid cells, correlates with subpial cortical demyelination and white matter lesion activity in progressive MS patients (2021) (1)
CCR6 Expression on B Cells Is Not Required for Clinical or Pathological Presentation of MOG Protein–Induced Experimental Autoimmune Encephalomyelitis despite an Altered Germinal Center Response (2021) (1)
Abstract 20690: B-Cell Deficiency in Mice With Hypomorphic c-myb Causes Diuresis and Reduces Blood Pressure (2017) (0)
Expression of lymphotoxin‐αβ on antigen‐specific T cells is required for dendritic cell function (2008) (0)
Faculty Opinions recommendation of IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. (2014) (0)
This information is current as Nervous System Stromal Cell Niches in the Inflamed Central (2017) (0)
Prematurely Follicular Dendritic Cells but Dissipate + CD 35 + Follicles in the Absence of FDC-M 1 Cluster Normally within Lymph Node AID-Expressing Germinal Center B Cells (2013) (0)
Intestinal protection without T cell help (2020) (0)
The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining (2018) (0)
305 Dynamic accumulation of plasmacytoid dendritic cells in lymph nodes is regulated by Type I IFN-β (2008) (0)
Low and transient salivary neutralizing antibodies after COVID vaccination (2022) (0)
Complement-associated Synaptic Reorganization in the Hippocampal CA2 Subfield in Multiple Sclerosis and Cuprizone-induced Myelin Loss (4554) (2020) (0)
Detection of iNOS/TNF in cells of the small intestinal lamina propria by FACS (2011) (0)
Immunity to SARS-CoV-2 persists 9 months post-symptoms with an altered T cell phenotype compared to influenza A virus-specific memory (2021) (0)
Assessing mucosal antibody responses to SARS-CoV-2 in humans and mice. (2022) (0)
Age-related susceptibility to grey matter demyelination and neurodegeneration is associated with meningeal neutrophil accumulation in an animal model of Multiple Sclerosis (2021) (0)
Perinatal Programming of Mucosal Stromal Cell Identity by the Lymphotoxin Pathway Regulates Mucosal Immune Responses in the Adult (2019) (0)
Potential Mechanism for Mast Cell Activation Responses to Acute Septic Peritonitis: A A Role for CD21/CD35 and CD19 in (2000) (0)
LIGHT is dispensable for CD4 1 and CD8 1 T cell and antibody responses to inﬂuenza A virus in mice (2006) (0)
Human B cell and glial cell interactions: Implications to the compartmentalized CNS inflammation of multiple sclerosis (MS) (2014) (0)
Managing the T.T.C. (1990) (0)
161 The role of lymphotoxin-beta-receptor signaling in dendritic cell function (2008) (0)
Faculty Opinions recommendation of MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. (2014) (0)
A murine model of meningeal inflammation and subpial demyelination identifies an anti-MOG independent mechanism of cortical injury that is inhibited by Siponimod therapy (2020) (0)
The Relation between Meningeal Inflammation, Cortical Demyelination and White Matter Lesional Activity in Chronic Multiple Sclerosis: a Pilot Study (P5.228) (2015) (0)
Neonatal LTβR signaling is required for the accumulation of eosinophils in the inflamed adult mesenteric lymph node (2022) (0)
An analysis of steel factor-stimulated receptor trafficking, survival signals and mitogenesis, understanding the role of c-Kit-associated signaling proteins (1998) (0)
Faculty Opinions recommendation of Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis. (2018) (0)
Ageing promotes non-remitting experimental autoimmune encephalomyelitis with persistent meningeal inflammation and subpial demyelination in A/T SJL/J mice. (2021) (0)
Type I interferon induced by lymphotoxin-beta receptor signaling on dendritic cell is crucial for CD8 T cell infiltration into effector site by modulating the expression of tissue specific adhesion molecule VLA4 (P5045) (2013) (0)
‘Cytokine defined’ B cell subsets in multiple sclerosis (2014) (0)
Intestinal protection without T cell help (2020) (0)
PS1-13 LT-βετα-R Signaling in dendritic cells induces a type I IFN response that integrates with CD40-derived signals for cross-priming of CD8+ T cells (2010) (0)
Data for Recirculating Intestinal IgA-producing cells Regulate Neuroinflammation via IL10 (2019) (0)
278 Lymphotoxin-beta receptor signaling in the intestine is critical for recruitment of dendtric cells that contribute to IGA class switch recombination (2008) (0)
Detection of small intestinal IgA+TNFα+iNOS+ CELLS by Immunofluorescence Microscopy (IF) (2011) (0)
Batf3-dependent dendritic cells impact T-cell responses differently between adult and neonatal mice in an intestinal viral infection. (2016) (0)
of Multiple Sclerosis Alter the Clinical Course of a Rodent Model Disease-Modifying Gene Candidates That Substrain Differences Reveal Novel (2010) (0)
Title: Mucosal versus systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients (2020) (0)
The Requirement of B-cells for Renal and Blood Pressure Homeostasis (2018) (0)
Age-related susceptibility to grey matter demyelination and neurodegeneration is associated with meningeal neutrophil accumulation in an animal model of MS (2022) (0)
Informed consent--the process. (1994) (0)
Response through Apoptosis AID and Caspase 8 Shape the Germinal Hakem (2013) (0)
c-Myb Exacerbates Atherosclerosis Through Regulation of Harmful B2 and Protective IgM-producing Antibody Secreting Cells (2018) (0)
Queen’s Gambit: B Cell to Follicle (2021) (0)
Age-dependent gray matter demyelination is associated with leptomeningeal neutrophil accumulation (2022) (0)
Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control (2023) (0)
Faculty Opinions recommendation of Infection drives meningeal engraftment by inflammatory monocytes that impairs CNS immunity. (2019) (0)
Immunopathology T Cells To Infiltrate a Self-Tissue and + CD 8 A Lymphotoxin / Type I IFN Axis Programs (2015) (0)
The 14th International TNF Conference, Québec City, Canada - Des Progrės Récents aux Défis Futurs (Recent Advances toward Future Challenges). (2014) (0)
A Th17/Lymphotoxin axis enables cytokine production by brain meningeal stromal cells and propagates de novo CNS-intrinsic T cell responses during inflammation (2014) (0)
A totally OSM gift to astrocytes relieves inflammation. (2021) (0)
Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis (2018) (0)
Expression of lymphotoxin-{alpha}{beta} on antigen-specific T cells is required for dendritic cell function (2008) (0)
Use of Inhibitors of the Lymphotoxin/LIGHT Axis to Manipulate Lymphoid Microenvironments and the Consequences for Immune Responses (2002) (0)
Faculty Opinions recommendation of Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility. (2014) (0)

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Other Resources About Jennifer Gommerman

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What Schools Are Affiliated With Jennifer Gommerman?

Jennifer Gommerman is affiliated with the following schools:

University of Toronto