Jenny P. Y. Ting

Q: What Schools Are Affiliated With Jenny P. Y. Ting

Jenny P. Y. Ting is affiliated with the following schools: University of Alabama, Illinois State University, Northwestern University, Stanford University, University of North Carolina at Chapel Hill

Jenny P. Y. Ting's AcademicInfluence.com Rankings

Jenny P. Y. Ting

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#3297

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#4350

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#965

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#143

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#146

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#20

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#578

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#598

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#109

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Jenny P. Y. Ting

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#1895

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#284

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#295

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#69

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Why Is Jenny P. Y. Ting Influential?

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According to Wikipedia, Jenny Pan-Yun Ting is a Taiwanese-American immunologist and microbiologist at University of North Carolina. She is a highly cited researcher who studies the role of NLR genes in regulating inflammation and how nanoparticles and microparticles can be used as vaccine adjuvants. She was president of the American Association of Immunologists from 2020 to 2021.

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Jenny P. Y. Ting's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
Inflammasomes: mechanism of action, role in disease, and therapeutics (2015) (2196)
The NLRP3 inflammasome: molecular activation and regulation to therapeutics (2019) (1832)
Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling (2011) (1465)
The inflammasome NLRs in immunity, inflammation, and associated diseases. (2011) (1430)
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. (2009) (1041)
The NLR gene family: a standard nomenclature. (2008) (805)
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2 (2006) (739)
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer (2010) (698)
Novel role of PKR in inflammasome activation and HMGB1 release (2012) (679)
Cutting Edge: Inflammasome Activation by Alum and Alum’s Adjuvant Effect Are Mediated by NLRP31 (2008) (666)
Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. (2008) (572)
Genetic Control of MHC Class II Expression (2002) (565)
NLRX1 is a regulator of mitochondrial antiviral immunity (2008) (559)
The Immunogenicity of Human Adipose‐Derived Cells: Temporal Changes In Vitro (2006) (523)
TNFα promotes proliferation of oligodendrocyte progenitors and remyelination (2001) (519)
TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination. (2001) (511)
Autophagy links inflammasomes to atherosclerotic progression. (2012) (490)
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling (2007) (418)
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. (2012) (411)
A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation? (2012) (403)
Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells (2009) (400)
CATERPILLER: a novel gene family important in immunity, cell death, and diseases. (2005) (379)
CATERPILLERs, pyrin and hereditary immunological disorders (2006) (368)
Mechanisms of NOD-like receptor-associated inflammasome activation. (2013) (366)
How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene (2000) (365)
NLRs at the intersection of cell death and immunity (2008) (365)
Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice (1998) (350)
NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses (2010) (340)
NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways1 (2009) (322)
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways. (2011) (312)
Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. (2007) (308)
Cutting Edge: CATERPILLER: A Large Family of Mammalian Genes Containing CARD, Pyrin, Nucleotide-Binding, and Leucine-Rich Repeat Domains1 (2002) (300)
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB (2012) (279)
Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome1 (2009) (266)
The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18 (2010) (258)
A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. (1990) (257)
Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter (1995) (257)
BLIMP-1 mediates extinction of major histocompatibility class II transactivator expression in plasma cells (2000) (248)
The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. (2012) (241)
Monocytic microparticles activate endothelial cells in an IL-1β-dependent manner. (2011) (232)
Induction of MHC class I expression by the MHC class II transactivator CIITA. (1997) (232)
Regulation of MHC gene expression. (1993) (225)
MEK Inhibition Enhances Paclitaxel-induced Tumor Apoptosis* (2000) (224)
NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. (2014) (221)
TLR2/MyD88/NF-κB Pathway, Reactive Oxygen Species, Potassium Efflux Activates NLRP3/ASC Inflammasome during Respiratory Syncytial Virus Infection (2012) (219)
Transcriptional Scaffold: CIITA Interacts with NF-Y, RFX, and CREB To Cause Stereospecific Regulation of the Class II Major Histocompatibility Complex Promoter (2000) (212)
NLR, the nucleotide-binding domain leucine-rich repeat containing gene family. (2008) (212)
De Novo Central Nervous System Processing of Myelin Antigen Is Required for the Initiation of Experimental Autoimmune Encephalomyelitis1 (2002) (212)
Paclitaxel (Taxol)-induced Gene Expression and Cell Death Are Both Mediated by the Activation of c-Jun NH2-terminal Kinase (JNK/SAPK)* (1998) (210)
MAVS-Mediated Apoptosis and Its Inhibition by Viral Proteins (2009) (210)
The CATERPILLER Protein Monarch-1 Is an Antagonist of Toll-like Receptor-, Tumor Necrosis Factor α-, and Mycobacterium tuberculosis-induced Pro-inflammatory Signals* (2005) (207)
Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt (2015) (206)
Two Distinct Gamma Interferon-Inducible Promoters of the Major Histocompatibility Complex Class II Transactivator Gene Are Differentially Regulated by STAT1, Interferon Regulatory Factor 1, and Transforming Growth Factor β (1999) (206)
NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice (2012) (198)
Type I IFN Triggers RIG-I/TLR3/NLRP3-dependent Inflammasome Activation in Influenza A Virus Infected Cells (2013) (197)
The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation (2014) (196)
Cutting Edge: CIAS1/Cryopyrin/PYPAF1/NALP3/ CATERPILLER 1.1 Is an Inducible Inflammatory Mediator with NF-κB Suppressive Properties (2003) (195)
Cutting Edge: NLRC5-Dependent Activation of the Inflammasome (2011) (188)
Epigenetic regulation of MHC-II and CIITA genes. (2006) (188)
Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity. (1997) (182)
Functional Genomic Analysis of Remyelination Reveals Importance of Inflammation in Oligodendrocyte Regeneration (2003) (178)
Cutting Edge: Monarch-1 Suppresses Non-Canonical NF-κB Activation and p52-Dependent Chemokine Expression in Monocytes1 (2007) (178)
Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha. (2003) (172)
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites (2020) (171)
Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice. (1996) (170)
Identification of Distinct Regions of 5′ Flanking DNA That Mediate Constitutive, IFN-γ, STAT1, and TGF-β-Regulated Expression of the Class II Transactivator Gene (1998) (165)
Nanoparticle clearance is governed by Th1/Th2 immunity and strain background. (2013) (162)
Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction. (1994) (159)
The intracellular innate immune sensor NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth (2017) (149)
CIITA-regulated plexin-A1 affects T-cell–dendritic cell interactions (2003) (148)
A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer. (2018) (147)
Cutting Edge: NLRP12 Controls Dendritic and Myeloid Cell Migration To Affect Contact Hypersensitivity (2010) (147)
CCAAT box binding protein NF‐Y facilitates in vivo recruitment of upstream DNA binding transcription factors. (1994) (147)
Chromosomal clustering of genes controlled by the aire transcription factor. (2005) (145)
Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1 (2010) (144)
Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. (2007) (144)
Criteria for effective design, construction, and gene knockdown by shRNA vectors (2006) (142)
The Transcriptional Regulatory Protein, YB-1, Promotes Single-stranded Regions in the DRA Promoter (*) (1995) (142)
Inhibition of IFN-γ Signaling by an Epstein-Barr Virus Immediate-Early Protein (2001) (133)
CATERPILLER 16.2 (CLR16.2), a Novel NBD/LRR Family Member That Negatively Regulates T Cell Function* (2005) (127)
NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses. (2016) (125)
HIV-1 Infection Induces Interleukin-1β Production via TLR8 Protein-dependent and NLRP3 Inflammasome Mechanisms in Human Monocytes* (2014) (124)
Cord Factor and Peptidoglycan Recapitulate the Th17-Promoting Adjuvant Activity of Mycobacteria through Mincle/CARD9 Signaling and the Inflammasome (2013) (122)
ATP Binding by Monarch-1/NLRP12 Is Critical for Its Inhibitory Function (2007) (118)
The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis. (2018) (117)
The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells. (2010) (116)
Enhancement of CIITA transcriptional function by ubiquitin (2003) (113)
Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization (2014) (113)
Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants. (1997) (113)
Absence of MHC class ii molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy (1994) (112)
GTP binding by class II transactivator: role in nuclear import. (1999) (109)
The SecA2 Secretion Factor of Mycobacterium tuberculosis Promotes Growth in Macrophages and Inhibits the Host Immune Response (2006) (107)
Differential Induction of Type I Interferon Responses in Myeloid Dendritic Cells by Mosquito and Mammalian-Cell-Derived Alphaviruses (2006) (106)
Discovery of a Viral NLR Homolog that Inhibits the Inflammasome (2011) (106)
Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines. (2011) (105)
Two Distinct Domains within CIITA Mediate Self-Association: Involvement of the GTP-Binding and Leucine-Rich Repeat Domains (2001) (104)
Inflammasomes and metabolic disorders: old genes in modern diseases. (2014) (102)
A noncanonical function of cGAMP in inflammasome priming and activation (2017) (101)
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes. (2005) (101)
Inflammasome inhibition as a pathogenic stealth mechanism. (2010) (100)
Identification of tumor-specific paclitaxel (Taxol)-responsive regulatory elements in the interleukin-8 promoter (1997) (99)
Histone Deacetylase 1/mSin3A Disrupts Gamma Interferon-Induced CIITA Function and Major Histocompatibility Complex Class II Enhanceosome Formation (2003) (98)
Mechanism of c-myc regulation by c-Myb in different cell lineages (1993) (92)
Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components (2015) (92)
A robust microparticle platform for a STING‐targeted adjuvant that enhances both humoral and cellular immunity during vaccination (2017) (91)
Analysis of NLRP3 in the Development of Allergic Airway Disease in Mice (2012) (90)
Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium. (2015) (89)
Taxol-dependent transcriptional activation of IL-8 expression in a subset of human ovarian cancer. (1996) (88)
Paclitaxel up-regulates interleukin-8 synthesis in human lung carcinoma through an NF-κB- and AP-1-dependent mechanism (2000) (88)
Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoter (1990) (87)
Upstream DNA sequences required for tissue-specific expression of the HLA-DR alpha gene. (1987) (87)
YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes (1994) (87)
Cutting Edge: ASC Mediates the Induction of Multiple Cytokines by Porphyromonas gingivalis via Caspase-1-Dependent and -Independent Pathways1 (2006) (86)
Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition. (2002) (86)
Regulation of mitochondrial antiviral signaling pathways. (2008) (86)
A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome. (1999) (86)
Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination. (2006) (84)
Cutting Edge: Monarch-1: A Pyrin/Nucleotide-Binding Domain/Leucine-Rich Repeat Protein That Controls Classical and Nonclassical MHC Class I Genes1 (2003) (84)
Microbiota maintain colonic homeostasis by activating TLR2/MyD88/PI3K signaling in IL-10-producing regulatory B cells. (2019) (84)
Cuprizone induces similar demyelination in male and female C57BL/6 mice and results in disruption of the estrous cycle (2010) (83)
The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. (2011) (82)
Expression and synthesis of murine immune response-associated (Ia) antigens by brain cells. (1981) (81)
CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo. (1998) (80)
Inflammasome-Associated Nucleotide-Binding Domain, Leucine-Rich Repeat Proteins and Inflammatory Diseases1 (2009) (79)
The NLR Adaptor ASC/PYCARD Regulates DUSP10, Mitogen-activated Protein Kinase (MAPK), and Chemokine Induction Independent of the Inflammasome* (2011) (79)
Cyclin-dependent kinase activation and S-phase induction of the cyclin B1 gene are linked through the CCAAT elements. (1997) (78)
Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits (1994) (77)
Reduced IL-4-, lipopolysaccharide-, and IFN-gamma-induced MHC class II expression in mice lacking class II transactivator due to targeted deletion of the GTP-binding domain. (1999) (77)
Inhibition of IFN-gamma signaling by an Epstein-Barr virus immediate-early protein. (2001) (77)
Deletion of ripA Alleviates Suppression of the Inflammasome and MAPK by Francisella tularensis (2010) (76)
Osteoblasts Express NLRP3, a Nucleotide‐Binding Domain and Leucine‐Rich Repeat Region Containing Receptor Implicated in Bacterially Induced Cell Death (2007) (75)
Detailed delineation of an interferon-gamma-responsive element important in human HLA-DRA gene expression in a glioblastoma multiform line. (1988) (75)
MHC class II exacerbates demyelination in vivo independently of T cells (2008) (73)
Arp2/3 Complex Is Required for Macrophage Integrin Functions but Is Dispensable for FcR Phagocytosis and In Vivo Motility. (2017) (73)
IL-10 Regulates Il12b Expression via Histone Deacetylation: Implications for Intestinal Macrophage Homeostasis (2012) (72)
Critical Role of Apoptotic Speck Protein Containing a Caspase Recruitment Domain (ASC) and NLRP3 in Causing Necrosis and ASC Speck Formation Induced by Porphyromonas gingivalis in Human Cells1 (2009) (71)
Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function (1991) (71)
The Protective Role of Nitric Oxide in a Neurotoxicant- Induced Demyelinating Model1 (2002) (71)
Porphyromonas gingivalis Mediates Inflammasome Repression in Polymicrobial Cultures through a Novel Mechanism Involving Reduced Endocytosis* (2012) (70)
Effects of paclitaxel on cytokine synthesis by unprimed human monocytes, T lymphocytes, and breast cancer cells (1998) (70)
The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy (2013) (70)
DJ-1 Enhances Cell Survival through the Binding of Cezanne, a Negative Regulator of NF-κB* (2010) (68)
Constitutive Expression of MHC Class II Genes in Melanoma Cell Lines Results from the Transcription of Class II Transactivator Abnormally Initiated from Its B Cell-Specific Promoter1 (2001) (68)
Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. (2005) (66)
Regulation of Class I Major Histocompatibility Complex (MHC) by Nucleotide-binding Domain, Leucine-rich Repeat-containing (NLR) Proteins* (2012) (64)
CCAAT-binding factor NF-Y and RFX are required for in vivo assembly of a nucleoprotein complex that spans 250 base pairs: the invariant chain promoter as a model (1997) (64)
In vivo footprint analysis of the HLA-DRA gene promoter: cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma. (1992) (64)
MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma (2014) (63)
Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene. (1998) (63)
Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome (2015) (62)
Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene. (1991) (62)
Positive Regulatory Domain I (PRDM1) and IRF8/PU.1 Counter-regulate MHC Class II Transactivator (CIITA) Expression during Dendritic Cell Maturation* (2011) (61)
Releasing Ski-Smad4 mediated suppression is essential to license Th17 differentiation (2017) (61)
Suppression of NLRX1 in chronic obstructive pulmonary disease. (2015) (61)
Analysis of the Murine Immune Response to Pulmonary Delivery of Precisely Fabricated Nano- and Microscale Particles (2013) (59)
Astroglial‐derived lymphotoxin‐α exacerbates inflammation and demyelination, but not remyelination (2005) (59)
A Novel Element and a TEF-2-like Element Activate the Major Histocompatibility Complex Class II Transactivator in B-lymphocytes* (1999) (59)
Differential selectivity of CIITA promoter activation by IFN-γ and IRF-1 in astrocytes and macrophages: CIITA promoter activation is not affected by TNF-α (1999) (58)
Transfection of Macrophage Inflammatory Protein 1α into B16 F10 Melanoma Cells Inhibits Growth of Pulmonary Metastases But Not Subcutaneous Tumors1 (2002) (58)
Regulation and Specificity of MHC2TA Promoter Usage in Human Primary T Lymphocytes and Cell Line1 (2002) (58)
Identification of an interferon-gamma response region 5' of the human histocompatibility leukocyte antigen DR alpha chain gene which is active in human glioblastoma multiforme lines. (1987) (57)
The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription. (2008) (57)
Identification of Class II Transcriptional Activator-Induced Genes by Representational Difference Analysis: Discoordinate Regulation of the DNα/DOβ Heterodimer1 (2000) (56)
Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses (2008) (56)
Heat Shock Protein 90 Associates with Monarch-1 and Regulates Its Ability to Promote Degradation of NF-κB-Inducing Kinase1 (2007) (56)
Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor. (2003) (55)
AIM2 in regulatory T cells restrains autoimmune diseases (2021) (54)
Improvements in obtaining and characterizing mouse cerebrospinal fluid☆ (1983) (54)
Differential regulation of cytokine-induced major histocompatibility complex class II expression and nitric oxide release in rat microglia and astrocytes by effectors of tyrosine kinase, protein kinase C, and cAMP (1997) (54)
Comparison and quantitation of Ia antigen expression on cultured macroglia and ameboid microglia from Lewis rat cerebral cortex: analyses and implications (1989) (53)
The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals (2016) (53)
Class II box consensus sequences in the HLA-DR alpha gene: transcriptional function and interaction with nuclear proteins (1989) (52)
Genetic Loss of Murine Pyrin, the Familial Mediterranean Fever Protein, Increases Interleukin-1β Levels (2012) (52)
A microparticle platform for STING-targeted immunotherapy enhances natural killer cell- and CD8+ T cell-mediated anti-tumor immunity. (2019) (51)
Acetalated Dextran Microparticles for Codelivery of STING and TLR7/8 Agonists. (2018) (51)
Immune plexins and semaphorins: old proteins, new immune functions (2012) (50)
Enhancement of DNA Vaccine Potency through Coadministration of CIITA DNA with DNA Vaccines via Gene Gun1 (2008) (50)
Prion‐like Aggregation of Mitochondrial Antiviral Signaling Protein in Lupus Patients Is Associated With Increased Levels of Type I Interferon (2016) (50)
Characterization of NLRP12 during the In Vivo Host Immune Response to Klebsiella pneumoniae and Mycobacterium tuberculosis (2013) (50)
Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon (2019) (48)
17β-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss (2010) (48)
Tumor Presence Induces Global Immune Changes and Enhances Nanoparticle Clearance. (2016) (48)
How Mouse Macrophages Sense What Is Going On (2016) (47)
A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells. (2017) (47)
NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25. (2019) (47)
NLRP 3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th 1 and Th 17 Responses (2010) (47)
EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex (2015) (46)
The Nucleotide-binding Leucine-rich Repeat (NLR) Family Member NLRX1 Mediates Protection against Experimental Autoimmune Encephalomyelitis and Represses Macrophage/Microglia-induced Inflammation* (2013) (45)
Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions. (2007) (45)
Investigation of tunable acetalated dextran microparticle platform to optimize M2e‐based influenza vaccine efficacy (2018) (44)
Lymphotoxin β Receptor (LtβR): Dual Roles in Demyelination and Remyelination and Successful Therapeutic Intervention Using LtβR–Ig Protein (2007) (44)
Innate PI3K p110δ Regulates Th1/Th17 Development and Microbiota-Dependent Colitis (2014) (44)
Towards programming immune tolerance through geometric manipulation of phosphatidylserine. (2015) (42)
Human major histocompatibility complex class II-associated invariant chain gene promoter. Functional analysis and in vivo protein/DNA interactions of constitutive and IFN-gamma-induced expression. (1993) (42)
The Innate Immune Sensor NLRC3 Acts as a Rheostat that Fine‐Tunes T Cell Responses in Infection and Autoimmunity (2018) (42)
Structural constraints within a trimeric transcriptional regulatory region. Constitutive and interferon-gamma-inducible expression of the HLA-DRA gene. (1992) (41)
NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated PKR translational inhibition (2017) (40)
Atopic asthmatic patients have reduced airway inflammatory cell recruitment after inhaled endotoxin challenge compared with healthy volunteers. (2012) (40)
Plexin-B2 Negatively Regulates Macrophage Motility, Rac, and Cdc42 Activation (2011) (40)
Corrigendum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth (2017) (40)
Plexin-B2 and Plexin-D1 in Dendritic Cells: Expression and IL-12/IL-23p40 Production (2012) (40)
Interleukin 2 responses of lpr and normal L3T4-/Lyt-2- T cells induced by TPA plus A23187. (1987) (39)
The CATERPILLER family: an ancient family of immune/apoptotic proteins. (2005) (39)
Serine Residues 286, 288, and 293 within the CIITA: A Mechanism for Down-Regulating CIITA Activity through Phosphorylation1 (2004) (38)
The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter. (1989) (38)
Cutting Edge: Rho Activation and Actin Polarization Are Dependent on Plexin-A1 in Dendritic Cells1 (2006) (37)
Identification of the Ankyrin Repeat Proteins ANKRA and RFXANK as Novel Partners of Class IIa Histone Deacetylases* (2005) (37)
MyD88 provides a protective role in long-term radiation-induced lung injury (2012) (37)
Characterization of NLRP12 during the Development of Allergic Airway Disease in Mice (2012) (36)
Multi-omics analyses reveal that HIV-1 alters CD4 T cell immunometabolism to fuel virus replication (2021) (36)
Transcriptional regulation of the HLA-DRA gene. (1991) (35)
Hierarchical contributions of allorecognition pathways in chronic lung rejection. (2003) (35)
Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum (2017) (35)
Regulation of Inosine-5′-monophosphate Dehydrogenase Type II Gene Expression in Human T Cells (1997) (35)
The Histone Acetyltransferase Domains of CREB-binding Protein (CBP) and p300/CBP-associated Factor Are Not Necessary for Cooperativity with the Class II Transactivator* (2001) (35)
Characterization of astrocyte nuclear proteins involved in IFN-gamma- and TNF-alpha-mediated class II MHC gene expression. (1994) (35)
TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model (2008) (35)
An NLRP3 Mutation Causes Arthropathy and Osteoporosis in Humanized Mice. (2016) (34)
H2-DMα−/− Mice Show the Importance of Major Histocompatibility Complex–Bound Peptide in Cardiac Allograft Rejection (2000) (34)
Airway cells from atopic asthmatic patients exposed to ozone display an enhanced innate immune gene profile. (2012) (34)
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
NLRP3 has a sweet tooth (2010) (33)
Combination gene therapy with CD86 and the MHC class II transactivator in the control of lung tumor growth. (1999) (33)
Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance. (2013) (32)
Plexin-D1 Is a Novel Regulator of Germinal Centers and Humoral Immune Responses (2011) (32)
Activation and transdominant suppression of MHC class II and HLA-DMB promoters by a series of C-terminal class II transactivator deletion mutants. (1997) (31)
Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR (2019) (31)
Blimp-1/PRDM1 Mediates Transcriptional Suppression of the NLR Gene NLRP12/Monarch-11 (2009) (31)
NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-λB signaling (2016) (31)
Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection* (2015) (31)
NLRX1 Facilitates Histoplasma capsulatum-Induced LC3-Associated Phagocytosis for Cytokine Production in Macrophages (2018) (30)
Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein. (2007) (30)
Expression of C5a in the brain does not exacerbate experimental autoimmune encephalomyelitis (2005) (30)
Sequences homologous to class II MHC W, X, and Y elements mediate constitutive and IFN-gamma-induced expression of human class II-associated invariant chain gene. (1991) (29)
Leucine-rich repeats of the class II transactivator control its rate of nuclear accumulation. (2002) (29)
Ia antigens on non-lymphoid tissues their origins and functions. (1982) (29)
X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements. (1990) (28)
NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency (2017) (27)
Differential suppression of interferon-γ-induced Ia antigen expression on cultured rat astroglia and microglia by second messengers☆ (1990) (27)
Cryopyrin: in from the cold. (2006) (27)
G Protein Signaling Modulator-3 Inhibits the Inflammasome Activity of NLRP3* (2014) (26)
Erratum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth (2017) (26)
The DMB promoter: delineation, in vivo footprint, trans-activation, and trans-dominant suppression. (1997) (26)
Pulmonary Delivery of Nanoparticle-Bound Toll-Like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer. (2020) (26)
Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals. (2008) (25)
Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase. (2007) (25)
Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription. (2007) (25)
Tyrosine phosphorylation of a c-Src-like protein is increased in membranes of CD4- CD8- T lymphocytes from lpr/lpr mice (1989) (25)
Biosynthesis and intracellular targeting of the lysosomal aspartic proteinase cathepsin D. (1998) (25)
Class II MHC genes: a model gene regulatory system with great biologic consequences. (1999) (24)
Major Histocompatibility Class II HLA-DRα Gene Expression in Thyrocytes: Counter Regulation by the Class II Transactivator and the Thyroid Y Box Protein. (1998) (24)
Usage of primary cells to delineate IFN-gamma-responsive DNA elements in the HLA-DRA promoter and to identify a novel IFN-gamma-enhanced nuclear factor. (1992) (24)
CATERPILLER (NLR) family members as positive and negative regulators of inflammatory responses. (2007) (24)
A CIITA‐independent pathway that promotes expression of endogenous rather than exogenous peptides in immune‐privileged sites (2004) (24)
The evolving role of semaphorins and plexins in the immune system: Plexin-A1 regulation of dendritic cell function (2008) (24)
Tumor necrosis factor alpha response elements in the HLA-DRA promoter: identification of a tumor necrosis factor alpha-induced DNA-protein complex in astrocytes. (1992) (24)
Differential selectivity of CIITA promoter activation by IFN-gamma and IRF-1 in astrocytes and macrophages: CIITA promoter activation is not affected by TNF-alpha. (1999) (23)
Individuals with increased inflammatory response to ozone demonstrate muted signaling of immune cell trafficking pathways (2012) (22)
ASC-dependent RIP2 Kinase Regulates Reduced PGE2 Production in Chronic Periodontitis (2012) (22)
The W element is a positive regulator of HLA-DRA transcription in various DR+ cell types. (1991) (22)
A beta-adrenergic agonist modulates DR alpha gene transcription via enhanced cAMP levels in a glioblastoma multiforme line. (1989) (21)
Analysis of the defect in IFN-gamma induction of MHC class II genes in G1B cells: identification of a novel and functionally critical leucine-rich motif (62-LYLYLQL-68) in the regulatory factor X 5 transcription factor. (1999) (21)
Inflammasomes in Myeloid Cells: Warriors Within. (2017) (21)
TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination (2020) (21)
Sputum inflammatory cells from patients with allergic rhinitis and asthma have decreased inflammasome gene expression. (2011) (19)
Gut microbiota, NLR proteins, and intestinal homeostasis (2020) (19)
NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity (2019) (18)
Selective Targeting of Leukemic Cell Growth in Vivo and in Vitro Using a Gene Silencing Approach to Diminish S-Adenosylmethionine Synthesis* (2008) (18)
The Toll–Like Receptor 2/6 Agonist, FSL–1 Lipopeptide, Therapeutically Mitigates Acute Radiation Syndrome (2017) (17)
NLRX1 has a tail to tell. (2012) (17)
Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance (2005) (17)
NLRs and the dangers of pollution and aging (2008) (16)
Identification of class II transcriptional activator-induced genes by representational difference analysis: discoordinate regulation of the DN alpha/DO beta heterodimer. (2000) (16)
Downregulation of Immune Signaling Genes in Patients With Large Surface Burn Injury (2007) (15)
Protein interactions at Sp1-like sites in the TGF alpha promoter as visualized by in vivo genomic footprinting. (1994) (15)
Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements (1992) (15)
NLRP3 moonlights in TH2 polarization (2015) (15)
The global response to the COVID-19 pandemic: how have immunology societies contributed? (2020) (15)
Current concepts in DRA gene regulation (1993) (14)
Innate Immune Cell Recovery Is Positively Regulated by NLRP12 during Emergency Hematopoiesis (2017) (14)
Prolonged survival of class II transactivator-deficient cardiac allografts (2002) (13)
STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN–Dependent and –Independent Immune-Regulatory Pathways (2021) (13)
Toward a molecular pathogenic pathway for Yersinia pestis YopM (2012) (12)
The SecA 2 Secretion Factor of Mycobacterium tuberculosis Promotes Growth in Macrophages and Inhibits the Host Immune Response (2006) (12)
Isolation and Characterization of a Human Pro α2(I) Collagen Gene Segment (1984) (12)
Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model. (2015) (12)
Brain Ia antigens have a bone marrow origin (2004) (11)
The expression and regulation of c-myb transcription in B6/lpr Lyt-2-, L3T4-T lymphocytes. (1987) (11)
Influenza Virus and SARS-CoV-2 Vaccines (2021) (10)
Affinity enrichment and functional characterization of TRAX1, a novel transcription activator and X1-sequence-binding protein of HLA-DRA (1995) (10)
Agitation by suffocation: how hypoxia activates innate immunity via the Warburg effect. (2013) (10)
Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC (2022) (10)
Cyclic-diGMP and cyclic-diAMP activate the NLRP 3 Inflammasome (2013) (9)
The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA. (1992) (9)
Mitochondrial GSDMD Pores DAMPen Pyroptosis. (2020) (9)
Molecular basis of elevated c-myb expression in the abnormal L3T4-, Lyt-2- T lymphocytes of autoimmune mice. (1987) (9)
Major histocompatibility class II HLA-DR alpha gene expression in thyrocytes: counter regulation by the class II transactivator and the thyroid Y box protein. (1998) (8)
The expression and detection of MHC class I antigens on murine neuroblastoma and ependymoblastoma lines (1987) (8)
Selective suppression of the murine autologous mixed lymphocyte reaction by physiological concentrations of hydrocortisone: effects on cell-surface Ia antigens. (1980) (8)
Inflammasome Assays In Vitro and in Mouse Models (2020) (8)
Evidence for methylation as a regulatory mechanism in HLA-DRx gene expression (2004) (7)
Distinct regions of 5′ flanking DNA that mediconstitutive, IFN-γ, STAT1, and TGF-3-regulated expression of the MHC class II transactivator, CIITA (1998) (6)
How the non-inflammasome NLRs function in the innate immune system (2014) (6)
Identification of an interferon-γ-responsive element of a class II major histocompatibility gene in rat type 1 astrocytes (1991) (6)
Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model (2015) (6)
NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity (2020) (6)
Suppression of NLRX 1 in chronic obstructive pulmonary disease (5)
Infection and inflammation: New perspectives on Alzheimer's disease (2022) (5)
Considering innate immune responses in SARS-CoV-2 infection and COVID-19 (2022) (5)
Differential expression of the HLA-DR genes in various melanoma cell lines treated with interferon-γ: Methylation of the HLA-DRα gene in these lines is not correlated with its expression (1987) (5)
NLRC5 dependent activation of the inflammasome in response to bacteria (114.8) (2012) (4)
Conservation of the promoter region of DRA-like genes from nonhuman primates (2004) (4)
Correction: Characterization of NLRP12 during the In Vivo Host Immune Response to Klebsiella pneumoniae and Mycobacterium tuberculosis (2013) (4)
Vitamin D insufficiency increases risk of chronic pain among African Americans experiencing motor vehicle collision. (2019) (4)
Faculty Opinions recommendation of Pyogenic bacterial infections in humans with IRAK-4 deficiency. (2003) (4)
Comparison of Ab−/−β, H2-DM−, and CIITA−/− in Second-Set Skin Allograft Rejection (2002) (4)
TLR9- and CD40-Targeting Vaccination Promotes Human B Cell Maturation and IgG Induction via pDC-Dependent Mechanisms in Humanized Mice (2021) (3)
A spike in inflammation (2018) (3)
Faculty Opinions recommendation of The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. (2002) (3)
Molecular Identification of Regulatory DNA Sequences for Basal and Gamma‐Interferon‐Induced Expression of HLA DRα in Human Multiforme Glioblastoma Cell Lines (1988) (3)
Reining in uncontrolled inflammasome with PKA (2016) (3)
Non–Cell-Autonomous Activity of the Hemidesmosomal Protein BP180/Collagen XVII in Granulopoiesis in Humanized NC16A Mice (2020) (3)
Canonical Inflammasomes Drive IFN-g to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium Graphical (3)
The innate immune receptor Nlrp12 suppresses autoimmunity to the retina (2022) (2)
Correction: Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome (2018) (2)
Comparison of Abeta(b-/-), H2-DM(-), and CIITA(-/-) in second-set skin allograft rejection. (2002) (2)
Identification of novel Mycoplasma hyorhinis gene fragments by differential display analysis of co-cultures. (2001) (2)
The Nlrp3 Inflammasome Affects Airway Inflammation, IgE/IL-13 Production And Mast Cell Function In A Subchronic Model Of Asthma (2010) (2)
Heat Shock Protein 90 Associates with Monarch-1 and Regulates Its Ability to Promote Degradation of NF- B-Inducing Kinase (2007) (2)
Faculty Opinions recommendation of NOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6. (2015) (2)
Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements (1992) (2)
Faculty Opinions recommendation of De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. (2004) (2)
Two different molecular pathways account for low IL-2 receptor and c-myc mRNA expression by lpr Lyt-2- L3T4- T cells. (1988) (2)
Rebuilding host-pathogen interaction from the ground up: in vitro reconstitution of the inflammasome. (2007) (2)
Evidence for methylation as a regulatory mechanism in HLA-DR alpha gene expression. (1985) (2)
Molecular control of class II by CIITA in CNS endothelial cells (1998) (2)
Isolation and characterization of a human pro alpha 2(I) collagen gene segment. (1984) (2)
Alloantigen recognition in the mouse heterotopic model of OB (2002) (1)
Differential expression of the HLA-DR genes in various melanoma cell lines treated with interferon-gamma: methylation of the HLA-DR alpha gene in these lines is not correlated with its expression. (1987) (1)
Nitric oxide exacerbates the course of pathology in a mouse model of demyelinating disesase (1998) (1)
Isolates of Salmonella typhimurium circumvent NLRP3 inflammasome recognition in macrophages during the chronic phase of infection (2021) (1)
Pathways Inflammasome-Dependent and-Independent HMGB 1 Release via Vivo Caspase-1 Activation , Necrosis , and NLRP 3 ( NALP 3 , Cryopyrin ) Facilitates In (2009) (1)
Abstract LB-126: Nanoparticle-incorporated STING activator as an immunotherapeutic for PD-L1 resistant triple-negative breast cancer (2018) (1)
Microenvironment and Immunology The Inflammasome Component Nlrp 3 Impairs Antitumor Vaccine by Enhancing the Accumulation of Tumor-Associated Myeloid-Derived Suppressor Cells (2010) (1)
NLRP12 limits TNFα-induced apoptosis of monocyte progenitor cells during emergency hematopoiesis (2016) (1)
1 Selective Targeting of Leukemic Cells Growth In Vivo and In Vitro Using a Gene Silencing Approach To Diminish S-Adenosylmethionine ( SAMe ) Synthesis (2008) (1)
STAT1, IRF-1, and TGF-beta mediate expression of the class II MHC transactivator, CIITA, by differential regulation of two distinct IFN-gamma-inducible promoters (1998) (1)
Erratum: How Stat1 mediates constitutive gene expression: A complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene (The EMBO Journal (2000) 19 (4111-4122)) (2000) (1)
NLRX1 promotes HIV-1 and DNA viruses replication by blocking STING-TBK1 innate immune signaling (2017) (1)
Author Correction: AIM2 in regulatory T cells restrains autoimmune diseases (2021) (1)
O3-S6.06 Self-collection vs physician-collection for the detection of Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis and Mycoplasma genitalium (2011) (0)
The function of MHC class II molecules on microglia during demyelination (1998) (0)
Caspase-1 And Absent In Melanoma 2 (AIM2) Are Involved In The Cell Death Response To Influenza A Infection In Airway Epithelial Cells (2012) (0)
Faculty Opinions recommendation of Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. (2015) (0)
NLR genes and adaptive and innate immunity (2009) (0)
Faculty Opinions recommendation of Toll-like receptor 4-MD-2 complex mediates the signal transduction induced by flavolipin, an amino acid-containing lipid unique to Flavobacterium meningosepticum. (2002) (0)
Erratum: The W element is a positive regulator of HLA-DRA transcription in various Dr+ cell types (Journal of Immunology (February 15, 1991) 4 (1361)) (1991) (0)
Cell Lung Carcinoma : Identification of RS / DJ-1 and RhoGDI Proteomic Profiling Drug-Induced Apoptosis in Non-Small Updated Version (2003) (0)
Faculty Opinions recommendation of Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. (2015) (0)
ATP-binding to the CATERPILLER protein Monarch-1, is required for its inhibitory function (44.19) (2007) (0)
Regulation of WHN expression in thymic epithelial cells (1998) (0)
Increasing Burn Size Dramatically Influences the Immune Response to Burn Injury: 156. (2006) (0)
Faculty Opinions recommendation of The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. (2004) (0)
NLRX1 is a regulator of the innate immune response to influenza A virus infection (2011) (0)
and β Transforming Growth Factor Interferon Regulatory Factor 1 , and Differentially Regulated by STAT 1 , Complex Class II Transactivator Gene Are Promoters of the Major Histocompatibility Two Distinct Gamma Interferon-Inducible (1998) (0)
NLRP12/Monarch-1 Suppression of the NLR Gene Blimp-1/PRDM1 Mediates Transcriptional (2009) (0)
Faculty Opinions recommendation of NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4. (2015) (0)
Modulation of MHC Antigen Expression and Disease: Control of MHC class II gene expression (1995) (0)
PL-5 New functions for NLR proteins: Cell death and type I IFN response (2008) (0)
Production in Chronic Periodontitis 2 ASC-dependent RIP 2 Kinase Regulates Reduced PGE (0)
Resource An NLRP 3 Mutation Causes Arthropathy and Osteoporosis in Humanized Mice (2017) (0)
the Inflammasome Activity of NLRP 3 G Protein Signaling Modulator-3 Inhibits Immunology : (2014) (0)
The innate immune receptor Nlrp12 participates in protection against experimental autoimmune uveitis (2016) (0)
Encephalomyelitis Initiation of Experimental Autoimmune of Myelin Antigen Is Required for the De Novo Central Nervous System Processing (2002) (0)
NLRX1 attenuates tumorigenesis through the negative regulation of AKT and NF-κB signaling (TUM7P.924) (2014) (0)
A direct, bioluminescent caspase-1 assay for monitoring inflammasome activation (2016) (0)
NLRX1 Facilitates HIV-1 Infection of CD4 T Cells by Promoting Oxidative Phosphorylation (2019) (0)
Selective Diminution of Leukemic Cell Growth by shRNA‐Mediated Targeting of S‐Adenosylmethionine (SAMe) Metabolism (2008) (0)
Regulation of the DN Difference Analysis : Discoordinate RepresentationalActivator-Induced Genes by Identification of Class II Transcriptional (2000) (0)
NLR genes: infection, inflammation and vaccines (2009) (0)
Abnormally Initiated from Its B Cell-Specific the Transcription of Class II Transactivator Genes in Melanoma Cell Lines Results from Constitutive Expression of MHC Class II (2001) (0)
Plexin-A1 on dendritic cells and its interaction with a T cell surface molecule (B11) (2007) (0)
Nucleotide-Binding, and Leucine-Rich Repeat of Mammalian Genes Containing CARD, Pyrin, Cutting Edge: CATERPILLER: A Large Family (2002) (0)
alphavirusrepliconpartikeln cancer vaccine containing (1999) (0)
Faculty Opinions recommendation of Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. (2015) (0)
Gamma-tocopherol Treatment Alters Expression of Cytokine and Major Histocompatibility Molecules (2009) (0)
Plexin-A4/Semaphorin 3A Signaling is Required for TLR- and Sepsis-induced Cytokine Storm (2010) (0)
NLRP12-deficiency results in TNFα-mediated bone marrow apoptosis during emergency hematopoiesis (INM2P.355) (2015) (0)
Protein Phosphatase 2A Catalytic Subunit α (PP2Ac) Plays a MyD88-dependent, Central Role in the Gene-Specific Regulation of Endotoxin Tolerance (ET) (2014) (0)
Faculty Opinions recommendation of NLRP4 negatively regulates autophagic processes through an association with beclin1. (2015) (0)
The Effect of MHC Class II Transactivator (CIITA) on the Growth and Metastasis of Breast Tumors. (1998) (0)
The Nucleotide‐binding Domain, Leucine‐rich Repeat‐containing Protein (NLR) Family of Intracellular Sensors (2011) (0)
Correction: Isolates of Salmonella typhimurium circumvent NLRP3 inflammasome recognition in macrophages during the chronic phase of infection. (2022) (0)
Faculty Opinions recommendation of Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. (2005) (0)
Acute inflammasome activation and downregulation after severe burn injury in humans. (169.23) (2012) (0)
Class I Genes Controls Classical and Nonclassical MHC Domain/Leucine-Rich Repeat Protein That Pyrin/Nucleotide-Binding Cutting Edge: Monarch-1: A (2003) (0)
Molecular identification of regulatory DNA sequences for basal and gamma-inteferon induced expression of HLA DRα in human multiforme glioblastoma cell lines (1987) (0)
Faculty Opinions recommendation of Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells. (2006) (0)
Distinct Immature Myeloid Populations Arise After Radiation Combined With Thermal Injury (2013) (0)
Faculty Opinions recommendation of Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. (2003) (0)
Influenza-Induced Expression Of Inflammasome Components Is Enhanced In The Asthmatic Airway Epithelium (2011) (0)
ModelNeurotoxicant-Induced Demyelinating The Protective Role of Nitric Oxide in a (2001) (0)
Move over NAIP, DDX17 diversifies the NLRC4 inflammasome (2021) (0)
CATERPILLERS R US: Novel Regulators of Inflammation and Apoptosis Preserved from Plants to Humans (2007) (0)
-Independent Pathways via Caspase-1-Dependent and gingivalis Porphyromonas Multiple Cytokines by Cutting Edge: ASC Mediates the Induction of (2006) (0)
with DNA Vaccines via Gene Gun through Coadministration of CIITA DNA Enhancement of DNA Vaccine Potency (2008) (0)
Abstract 1319: Monitoring inflammasome activation with a bioluminescent caspase-1 assay (2015) (0)
The NLR (NBD-LRR containing) Family of Intracellular Sensors in Inflammation and Immune Response. (2009) (0)
Large U.S. Hispanic Study Suggests Role For NLR Pathway In Asthma, Allergy, And Related Traits (2010) (0)
Nitric oxide inhibits major histocompatibility complex class ii expression on murine dendritic cells (2000) (0)
Faculty Opinions recommendation of Mutations in NALP12 cause hereditary periodic fever syndromes. (2008) (0)
Faculty Opinions recommendation of Nod2 suppresses Borrelia burgdorferi mediated murine Lyme arthritis and carditis through the induction of tolerance. (2015) (0)
Transactivator Transcription by the MHC Class II Cutting Edge : Activation of HIV-1 (2000) (0)
NLRP12 suppresses host innate immune signaling to limit inflammation during emergency hematopoiesis (INM6P.404) (2014) (0)
Importance of microtubules for ia antigen present- ation. Abstr. (1979) (0)
Faculty Opinions recommendation of NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. (2015) (0)
Immunity Previews NLRX 1 Has a Tail to Tell (0)
Erratum: Activation of the HLA-DRA gene in primary human T lymphocytes: Novel usage of TATA and the X and Y promoter elements (Molecular and Cellular Biology 12:12 (5615)) (1993) (0)
Neurotransmitter modulation of the human class II gene DRα on multiforme glioblastoma cell lines: A molecular analysis (1987) (0)
Evidence for chromatin structure as a regulatory determinant in HLA-DR alpha gene expression. (1985) (0)
Characterization of a functional domain in the class II transactivator (CIITA) (1998) (0)
CIITA Activity through Phosphorylation CIITA: A Mechanism for Down-Regulating Serine Residues 286, 288, and 293 within the (2004) (0)
Radiation combined with thermal injury: induction of a radio-resistant immature myeloid cell. (118.10) (2012) (0)
Macrophage Homeostasis Deacetylation: Implications for Intestinal Expression via Histone Il12b IL-10 Regulates (2012) (0)
Human Major Histocompatibility Complex Class 11-associated Invariant Chain Gene Promoter (2001) (0)
Domain Targeted Deletion of the GTP-Binding Mice Lacking Class II Transactivator Due to-Induced MHC Class II Expression in γ IFN-Reduced IL-4-, Lipopolysaccharide-, and Koller and (1999) (0)
Genomic mining of new genes and pathways in innate and adaptive immunity. (2005) (0)
Faculty Opinions recommendation of XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. (2008) (0)
Donor-specific transfusion and anti-CD154 induces tracheal allograft tolerance via peripheral deletion and regulatory T cells (2005) (0)
Inflammatory Gene Expression Differentiates With Airway Neutrophil Response To Ozone (2012) (0)
Colitis Development and Microbiota-Dependent Regulates Th 1 / Th 17 δ Innate PI 3 K p 110 Sartor and (2014) (0)
738 The Phosphoinositide 3-Kinase Subunit P1105 Regulates TH1/TH17 Skewing in Murine and Human IBD (2013) (0)
Functional Analysis ofc-MybProtein inT-Lymphocytic CellLines ShowsthatIttrans-Activates thec-myc Promoter (1990) (0)
Faculty Opinions recommendation of Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. (2004) (0)
Radiation Combined With Thermal Injury Results in Specific Alterations in Adaptive and Innate Immune Cell Populations (2012) (0)
Neurotransmitter Modulation of the Human Class II Gene DRα on Multiforme Glioblastoma Cell Lines A Molecular Analysis (1988) (0)
Robust Anti-SARS-CoV-2 Humoral and Cellular Immunity through cGAMP-loaded Microparticle Adjuvanted Subunit Vaccination (2021) (0)
The adaptor protein ASC controls transplantation outcomes independently of the inflammasome (TRAN1P.951) (2015) (0)
The Role of the IL-1β Pathway in Severe Acute Respiratory Syndrome Coronavirus 2 Infection of Human Airway Epithelia (2023) (0)
in Human Cells Porphyromonas gingivalis ASC Speck Formation Induced by (ASC) and NLRP3 in Causing Necrosis and Containing a Caspase Recruitment Domain Critical Role of Apoptotic Speck Protein (2009) (0)
Combined radiation and thermal injury induces a non-suppressive myeloid CD11b+ Gr1+ cell population (P4025) (2013) (0)
A Conversation with Dr. Jenny Ting. (2021) (0)
The innate immune receptor Nlrp12 suppresses autoimmunity to the retina (2022) (0)
Interferon activated gene 204 (Ifi204) protects against bone loss in experimental periodontitis. (2022) (0)
TRAF3IP3 negatively regulates type I interferon signaling by suppressing TBK1 (2019) (0)
Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in PSC (2021) (0)
A role for the NLR family members NLRC4 and NLRP3 in sterile inflammasome activation in glial cells (2017) (0)

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