Jens Nielsen

Q: What Schools Are Affiliated With Jens Nielsen

Jens Nielsen is affiliated with the following schools: King's College London, Beijing University of Chemical Technology, Technical University of Denmark, University of Southern Denmark, University of Oxford, University College London, Chalmers University of Technology, KTH Royal Institute of Technology

Jens Nielsen's AcademicInfluence.com Rankings

Jens Nielsen

Engineering

#929

World Rank

#1450

Historical Rank

Bioengineering

World Rank

Historical Rank

Applied Physics

#62

World Rank

#65

Historical Rank

engineering Degrees

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Engineering

Jens Nielsen's Degrees

PhD Biomechanical Engineering Technical University of Denmark
Masters Mechanical Engineering Technical University of Denmark

Why Is Jens Nielsen Influential?

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According to Wikipedia, Jens Nielsen is the CEO of BioInnovation Institute, Copenhagen, Denmark, and professor of systems biology at Chalmers University of Technology, Gothenburg, Sweden. He is also an adjunct professor at the Technical University of Denmark. Nielsen is the most cited researcher in the field of metabolic engineering, and he is the founding president of the International Metabolic Engineering Society. He has additionally founded several biotech companies.

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Jens Nielsen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Tissue-based map of the human proteome (2015) (9179)
Gut metagenome in European women with normal, impaired and diabetic glucose control (2013) (2206)
Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics* (2013) (1732)
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88 (2007) (1123)
Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network. (2003) (1106)
Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics. (2014) (1016)
Fuel ethanol production from lignocellulose: a challenge for metabolic engineering and process integration (2001) (1009)
A community-driven global reconstruction of human metabolism (2013) (974)
Symptomatic atherosclerosis is associated with an altered gut metagenome (2012) (911)
Engineering Cellular Metabolism (2016) (817)
Metabolic Engineering: Principles And Methodologies (1998) (807)
Bioreaction Engineering Principles (1994) (751)
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology (2008) (601)
Minimum Information about a Biosynthetic Gene cluster. (2015) (600)
Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation (2015) (596)
Uncovering transcriptional regulation of metabolism by using metabolic network topology. (2005) (593)
Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods (2013) (583)
Mass spectrometry in metabolome analysis. (2005) (569)
Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution. (2016) (520)
Metabolic Engineering of Saccharomyces cerevisiae (2000) (501)
Evolutionary programming as a platform for in silico metabolic engineering (2005) (456)
Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease (2014) (416)
Reconstruction of Genome-Scale Active Metabolic Networks for 69 Human Cell Types and 16 Cancer Types Using INIT (2012) (389)
Global metabolite analysis of yeast: evaluation of sample preparation methods (2005) (388)
Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network (2003) (387)
Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries (2012) (384)
Assessing the Human Gut Microbiota in Metabolic Diseases (2013) (382)
OptFlux: an open-source software platform for in silico metabolic engineering (2010) (380)
Network Identification and Flux Quantification in the Central Metabolism of Saccharomyces cerevisiae under Different Conditions of Glucose Repression (2001) (377)
Flux distributions in anaerobic, glucose-limited continuous cultures of Saccharomyces cerevisiae. (1997) (364)
The RAVEN Toolbox and Its Use for Generating a Genome-scale Metabolic Model for Penicillium chrysogenum (2013) (363)
In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production. (2006) (352)
Increasing NADH oxidation reduces overflow metabolism in Saccharomyces cerevisiae (2007) (343)
Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88. (2011) (336)
Altered sterol composition renders yeast thermotolerant (2014) (331)
Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88 (2011) (327)
Recon3D: A Resource Enabling A Three-Dimensional View of Gene Variation in Human Metabolism (2018) (319)
A comprehensive comparison of RNA-Seq-based transcriptome analysis from reads to differential gene expression and cross-comparison with microarrays: a case study in Saccharomyces cerevisiae (2012) (319)
Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome. (2015) (306)
Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae (2010) (305)
Metabolic engineering of yeast for production of fuels and chemicals. (2013) (293)
Identification of anticancer drugs for hepatocellular carcinoma through personalized genome‐scale metabolic modeling (2014) (292)
Improving the phenotype predictions of a yeast genome‐scale metabolic model by incorporating enzymatic constraints (2017) (289)
Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories (2016) (279)
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans. (2018) (276)
Modeling Lactococcus lactis using a genome-scale flux model (2005) (263)
De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology (2012) (257)
Establishing a platform cell factory through engineering of yeast acetyl-CoA metabolism. (2013) (253)
The gut microbiota modulates host amino acid and glutathione metabolism in mice (2015) (252)
Reproducibility of Oligonucleotide Microarray Transcriptome Analyses (2002) (251)
The Metabolic Response of Heterotrophic Arabidopsis Cells to Oxidative Stress1[W] (2006) (250)
Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism. (2005) (248)
Growth-rate regulated genes have profound impact on interpretation of transcriptome profiling in Saccharomyces cerevisiae (2006) (246)
Kinetic models in industrial biotechnology - Improving cell factory performance. (2014) (246)
Characterization of chromosomal integration sites for heterologous gene expression in Saccharomyces cerevisiae (2009) (240)
The next wave in metabolome analysis. (2005) (235)
Optimization of ethanol production in Saccharomyces cerevisiae by metabolic engineering of the ammonium assimilation. (2000) (231)
The probiotic potential against vibriosis of the indigenous microflora of rainbow trout. (2001) (227)
Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals (2014) (226)
Microbial acetyl-CoA metabolism and metabolic engineering. (2015) (225)
Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering. (2009) (224)
De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae. (2015) (219)
Understanding the interactions between bacteria in the human gut through metabolic modeling (2013) (218)
Integration of clinical data with a genome-scale metabolic model of the human adipocyte (2013) (216)
MEMOTE for standardized genome-scale metabolic model testing (2020) (214)
Glucose repression in Saccharomyces cerevisiae (2015) (213)
Integration of gene expression data into genome-scale metabolic models. (2004) (212)
EasyClone: method for iterative chromosomal integration of multiple genes in Saccharomyces cerevisiae (2013) (211)
Production of plant sesquiterpenes in Saccharomyces cerevisiae: Effect of ERG9 repression on sesquiterpene biosynthesis (2008) (210)
Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity. (2005) (206)
Molecular Monolayers and Interfacial Electron Transfer of Pseudomonas aeruginosa Azurin on Au(111) (2000) (204)
Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger (2008) (202)
Metabolite profiling of fungi and yeast: from phenotype to metabolome by MS and informatics. (2005) (199)
Glucose control in Saccharomyces cerevisiae: the role of Mig1 in metabolic functions. (1998) (198)
Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals. (2015) (192)
Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch mode. (2012) (192)
RAVEN 2.0: A versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor (2018) (189)
It Is All about MetabolicFluxes (2003) (187)
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis (2020) (186)
Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices (2021) (186)
Metabolic flux distributions in Penicillium chrysogenum during fed‐batch cultivations (1995) (184)
Improving Production of Malonyl Coenzyme A-Derived Metabolites by Abolishing Snf1-Dependent Regulation of Acc1 (2014) (184)
Simultaneous analysis of amino and nonamino organic acids as methyl chloroformate derivatives using gas chromatography-mass spectrometry. (2003) (183)
Use of genome-scale microbial models for metabolic engineering. (2004) (183)
Diversion of Flux toward Sesquiterpene Production in Saccharomyces cerevisiae by Fusion of Host and Heterologous Enzymes (2010) (183)
Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene. (2019) (181)
Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis (2018) (181)
High-throughput screening for industrial enzyme production hosts by droplet microfluidics. (2014) (178)
Establishment of a yeast platform strain for production of p-coumaric acid through metabolic engineering of aromatic amino acid biosynthesis. (2015) (178)
The genome-scale metabolic model iIN800 of Saccharomyces cerevisiae and its validation: a scaffold to query lipid metabolism (2008) (176)
Establishing a synthetic pathway for high-level production of 3-hydroxypropionic acid in Saccharomyces cerevisiae via β-alanine. (2015) (175)
Measuring enzyme activities under standardized in vivo‐like conditions for systems biology (2010) (174)
Recon3D enables a three-dimensional view of gene variation in human metabolism (2018) (174)
Increasing galactose consumption by Saccharomyces cerevisiae through metabolic engineering of the GAL gene regulatory network (2000) (174)
The human secretome (2019) (174)
Advanced biofuel production by the yeast Saccharomyces cerevisiae. (2013) (174)
Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae. (2012) (172)
Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species (2017) (171)
Morphology and physiology of an α‐amylase producing strain of Aspergillus oryzae during batch cultivations (2000) (170)
Production of natural products through metabolic engineering of Saccharomyces cerevisiae. (2015) (168)
In silico genome‐scale reconstruction and validation of the Corynebacterium glutamicum metabolic network (2009) (167)
Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p (2009) (165)
Impact of systems biology on metabolic engineering of Saccharomyces cerevisiae. (2008) (165)
Large-scale evaluation of in silico gene deletions in Saccharomyces cerevisiae. (2003) (163)
High-throughput metabolic state analysis: the missing link in integrated functional genomics of yeasts. (2005) (162)
Sampling the Solution Space in Genome-Scale Metabolic Networks Reveals Transcriptional Regulation in Key Enzymes (2010) (162)
Metabolic engineering: techniques for analysis of targets for genetic manipulations. (1998) (160)
Industrial Systems Biology of Saccharomyces cerevisiae Enables Novel Succinic Acid Cell Factory (2013) (159)
Industrial systems biology. (2010) (159)
A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism (2019) (159)
Metabolome Analysis: An Introduction (2007) (157)
Durable SOC stacks for production of hydrogen and synthesis gas by high temperature electrolysis (2011) (157)
Anaerobic and aerobic batch cultivations of Saccharomyces cerevisiae mutants impaired in glycerol synthesis (2000) (154)
Integration of metabolome data with metabolic networks reveals reporter reactions (2006) (151)
Two-Dimensional Cysteine and Cystine Cluster Networks on Au(111) Disclosed by Voltammetry and in Situ Scanning Tunneling Microscopy (2000) (151)
An atlas of human metabolism (2020) (151)
Engineering synergy in biotechnology. (2014) (151)
Third-generation biorefineries as the means to produce fuels and chemicals from CO2 (2020) (148)
Production of biopharmaceutical proteins by yeast (2012) (147)
Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae. (2009) (147)
Metabolic engineering strategies for microbial synthesis of oleochemicals. (2015) (146)
Architecture of transcriptional regulatory circuits is knitted over the topology of bio-molecular interaction networks (2008) (143)
Purification and properties of a cellulase from Aspergillus niger. (1977) (143)
On-line and in situ monitoring of biomass in submerged cultivations (1997) (142)
Antibiotic Overproduction in Streptomyces coelicolor A3(2) Mediated by Phosphofructokinase Deletion* (2008) (142)
Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae (2011) (141)
Synergies between synthetic biology and metabolic engineering (2011) (141)
Systems biology of antibiotic production by microorganisms. (2007) (139)
Absolute Quantification of Protein and mRNA Abundances Demonstrate Variability in Gene-Specific Translation Efficiency in Yeast. (2017) (138)
Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae (2010) (138)
Functional expression and characterization of five wax ester synthases in Saccharomyces cerevisiae and their utility for biodiesel production (2012) (137)
Unravelling evolutionary strategies of yeast for improving galactose utilization through integrated systems level analysis (2011) (137)
Regulation of amino-acid metabolism controls flux to lipid accumulation in Yarrowia lipolytica (2016) (135)
Harnessing Yeast Peroxisomes for Biosynthesis of Fatty-Acid-Derived Biofuels and Chemicals with Relieved Side-Pathway Competition. (2016) (132)
A trispecies Aspergillus microarray: Comparative transcriptomics of three Aspergillus species (2008) (132)
Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism (2014) (130)
Fifteen years of large scale metabolic modeling of yeast: developments and impacts. (2012) (130)
Improvement of Galactose Uptake in Saccharomyces cerevisiae through Overexpression of Phosphoglucomutase: Example of Transcript Analysis as a Tool in Inverse Metabolic Engineering (2005) (130)
The influence of nitrogen sources on the α-amylase productivity of Aspergillus oryzae in continuous cultures (2000) (130)
Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae (2012) (129)
Rewiring carbon metabolism in yeast for high level production of aromatic chemicals (2019) (129)
Guidelines and recommendations on yeast cell death nomenclature (2018) (129)
Pellet Formation and Fragmentation in Submerged Cultures of Penicillium chrysogenum and Its Relation to Penicillin Production (1995) (128)
Systems Biology of Metabolism: A Driver for Developing Personalized and Precision Medicine. (2017) (128)
Mathematical modelling of metabolism. (2000) (128)
Metabolic footprinting in microbiology: methods and applications in functional genomics and biotechnology. (2008) (127)
Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2‐oxoglutarate due to depletion of the NADPH pool (2001) (127)
Engineering yeast for high-level production of stilbenoid antioxidants (2016) (127)
Microbial isoprenoid production: an example of green chemistry through metabolic engineering. (2005) (126)
Coupled incremental precursor and co-factor supply improves 3-hydroxypropionic acid production in Saccharomyces cerevisiae. (2014) (125)
Metabolic network analysis of Penicillium chrysogenum using (13)C-labeled glucose. (2000) (125)
Human gut microbiota and healthy aging: Recent developments and future prospective (2016) (125)
Different expression systems for production of recombinant proteins in Saccharomyces cerevisiae (2012) (124)
Chromosome 3p loss of heterozygosity is associated with a unique metabolic network in clear cell renal carcinoma (2014) (124)
Improved production of fatty acid ethyl esters in Saccharomyces cerevisiae through up-regulation of the ethanol degradation pathway and expression of the heterologous phosphoketolase pathway (2014) (123)
Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD (2017) (122)
DCEO Biotechnology: Tools To Design, Construct, Evaluate, and Optimize the Metabolic Pathway for Biosynthesis of Chemicals. (2018) (122)
Transcriptomics resources of human tissues and organs (2016) (121)
Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance. (2016) (121)
A gRNA-tRNA array for CRISPR-Cas9 based rapid multiplexed genome editing in Saccharomyces cerevisiae (2019) (119)
The influence of carbon sources and morphology on nystatin production by Streptomyces noursei. (2002) (119)
Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials (2012) (119)
Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast (2015) (118)
Mapping condition-dependent regulation of metabolism in yeast through genome-scale modeling (2013) (118)
Biobased organic acids production by metabolically engineered microorganisms. (2016) (118)
High Throughput Screening for the Design and Optimization of Chromatographic Processes - Miniaturization, Automation and Parallelization of Breakthrough and Elution Studies (2008) (118)
Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks. (2013) (117)
A systems-level approach for metabolic engineering of yeast cell factories. (2012) (116)
Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains. (2010) (116)
Profiling of Cytosolic and Peroxisomal Acetyl-CoA Metabolism in Saccharomyces cerevisiae (2012) (116)
Molecular Basis for Mycophenolic Acid Biosynthesis in Penicillium brevicompactum (2011) (116)
Yeast Systems Biology: Model Organism and Cell Factory (2019) (116)
A Closer Look at Bacteroides: Phylogenetic Relationship and Genomic Implications of a Life in the Human Gut (2011) (115)
Opportunities for yeast metabolic engineering: Lessons from synthetic biology (2011) (115)
Natural computation meta-heuristics for the in silico optimization of microbial strains (2008) (115)
Metabolic network analysis. A powerful tool in metabolic engineering. (2000) (114)
Fermentation performance and intracellular metabolite patterns in laboratory and industrial xylose-fermenting Saccharomyces cerevisiae (2002) (114)
Characterization of global yeast quantitative proteome data generated from the wild-type and glucose repression saccharomyces cerevisiae strains: the comparison of two quantitative methods. (2008) (114)
Systems Biology of Metabolism. (2017) (113)
Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes (2018) (112)
Systemic analysis of the response of Aspergillus niger to ambient pH (2009) (111)
The 2008 update of the Aspergillus nidulans genome annotation: a community effort. (2009) (111)
Metabolic Trade-offs in Yeast are Caused by F1F0-ATP synthase (2016) (111)
Flux Control at the Malonyl-CoA Node through Hierarchical Dynamic Pathway Regulation in Saccharomyces cerevisiae. (2016) (109)
Reconstruction of the yeast Snf1 kinase regulatory network reveals its role as a global energy regulator (2009) (109)
Can yeast systems biology contribute to the understanding of human disease? (2008) (109)
Impact of 'ome' analyses on inverse metabolic engineering. (2004) (108)
BioMet Toolbox: genome-wide analysis of metabolism (2010) (107)
Reconstruction of the central carbon metabolism of Aspergillus niger. (2003) (106)
Transcriptional, Proteomic, and Metabolic Responses to Lithium in Galactose-grown Yeast Cells* (2003) (106)
Metabolic engineering of yeast for fermentative production of flavonoids. (2017) (106)
Physiological Engineering Aspects Of Penicillium Chrysogenum (1997) (105)
Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. (2008) (105)
abYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction. (2017) (105)
Metabolic engineering of -lactam production (2003) (105)
Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization. (2015) (105)
Systems biology of lipid metabolism: From yeast to human (2009) (105)
Rapid quantification of yeast lipid using microwave-assisted total lipid extraction and HPLC-CAD. (2013) (104)
Parallel kinetic Monte Carlo simulation framework incorporating accurate models of adsorbate lateral interactions. (2013) (104)
Improving biobutanol production in engineered Saccharomyces cerevisiae by manipulation of acetyl-CoA metabolism (2013) (104)
Growth Temperature Exerts Differential Physiological and Transcriptional Responses in Laboratory and Wine Strains of Saccharomyces cerevisiae (2008) (103)
Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism (2020) (103)
Engineering of vesicle trafficking improves heterologous protein secretion in Saccharomyces cerevisiae. (2012) (102)
Metabolic Engineering of Ammonium Assimilation in Xylose-Fermenting Saccharomyces cerevisiae Improves Ethanol Production (2003) (102)
A simple and reliable method for the determination of cellular RNA content (1991) (101)
Growth energetics and metabolic fluxes in continuous cultures of Penicillium chrysogenum. (1996) (100)
From genomes to in silico cells via metabolic networks. (2005) (100)
Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid ethyl esters, an advanced biofuel, by eliminating non-essential fatty acid utilization pathways (2014) (100)
Genome‐scale modeling of human metabolism – a systems biology approach (2013) (99)
A functional genomics approach using metabolomics and in silico pathway analysis. (2002) (99)
Growth and α-amylase production by Aspergillus oryzae during continuous cultivations (1996) (98)
Complete genomic and transcriptional landscape analysis using third-generation sequencing: a case study of Saccharomyces cerevisiae CEN.PK113-7D (2018) (96)
Pharmaceutical protein production by yeast: towards production of human blood proteins by microbial fermentation. (2012) (95)
Quantitative Analysis of Glycerol Accumulation, Glycolysis and Growth under Hyper Osmotic Stress (2013) (95)
Toward design-based engineering of industrial microbes. (2010) (95)
From flavors and pharmaceuticals to advanced biofuels: production of isoprenoids in Saccharomyces cerevisiae. (2013) (94)
Modifying Yeast Tolerance to Inhibitory Conditions of Ethanol Production Processes (2015) (94)
Engineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiae (2012) (93)
Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine (2015) (93)
A Simple morphologically structured model describing the growth of filamentous microorganisms (1993) (93)
Genetic and nutrient modulation of acetyl-CoA levels in Synechocystis for n-butanol production (2015) (92)
Engineering of synthetic, stress-responsive yeast promoters (2016) (91)
Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies (2017) (91)
Engineering and systems-level analysis of Saccharomyces cerevisiae for production of 3-hydroxypropionic acid via malonyl-CoA reductase-dependent pathway (2016) (91)
Using Transcriptomics To Improve Butanol Tolerance of Synechocystis sp. Strain PCC 6803 (2013) (90)
Modelling approaches for studying the microbiome (2019) (90)
Long-chain alkane production by the yeast Saccharomyces cerevisiae. (2015) (90)
Systems biology of yeast: enabling technology for development of cell factories for production of advanced biofuels. (2012) (90)
Production of farnesene and santalene by Saccharomyces cerevisiae using fed-batch cultivations with RQ-controlled feed. (2016) (89)
Use of genome‐scale metabolic models for understanding microbial physiology (2010) (89)
Improved polyhydroxybutyrate production by Saccharomyces cerevisiae through the use of the phosphoketolase pathway (2013) (88)
Expanding the product portfolio of fungal type I fatty acid synthases. (2017) (88)
Analysis of Aspergillus nidulans metabolism at the genome-scale (2008) (88)
Hyphal growth and fragmentation of Penicillium chrysogenum in submerged cultures (1995) (88)
Manipulation of malic enzyme in Saccharomyces cerevisiae for increasing NADPH production capacity aerobically in different cellular compartments. (2004) (87)
Advancing metabolic engineering through systems biology of industrial microorganisms. (2015) (87)
From next-generation sequencing to systematic modeling of the gut microbiome (2015) (87)
Improved annotation through genome-scale metabolic modeling of Aspergillus oryzae (2008) (86)
Adipose Tissue Resting Energy Expenditure and Expression of Genes Involved in Mitochondrial Function Are Higher in Women than in Men (2012) (86)
Versatile Enzyme Expression and Characterization System for Aspergillus nidulans, with the Penicillium brevicompactum Polyketide Synthase Gene from the Mycophenolic Acid Gene Cluster as a Test Case (2011) (86)
A systems biology approach to study glucose repression in the yeast Saccharomyces cerevisiae (2007) (86)
Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism (2015) (86)
Investigation of the impact of MIG1 and MIG2 on the physiology of Saccharomyces cerevisiae. (1999) (84)
Prospects for microbial biodiesel production (2011) (84)
Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses (2015) (84)
Intracellular metabolite profiling of Fusarium oxysporum converting glucose to ethanol. (2005) (83)
Simultaneous overexpression of enzymes of the lower part of glycolysis can enhance the fermentative capacity of Saccharomyces cerevisiae (2000) (83)
Computer simulations reveal complex distribution of haemodynamic forces in a mouse retina model of angiogenesis (2013) (83)
Development of fungal cell factories for the production of secondary metabolites: Linking genomics and metabolism (2017) (83)
Modelling the morphology of filamentous microorganisms (1996) (83)
Development of fungal cell factories for the production of secondary metabolites: Linking genomics and metabolism (2017) (83)
Metabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community (2021) (82)
Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis (2015) (81)
Evolutionary engineering of Saccharomyces cerevisiae for efficient aerobic xylose consumption. (2012) (81)
Compositional and functional differences of the mucosal microbiota along the intestine of healthy individuals (2019) (81)
Enhanced citrate production through gene insertion in Aspergillus niger. (2008) (81)
Synthetic Biology for Engineering Acetyl Coenzyme A Metabolism in Yeast (2014) (81)
Genome scale metabolic modeling of cancer. (2017) (81)
Network analyses identify liver‐specific targets for treating liver diseases (2017) (81)
Genome-scale metabolic reconstructions of Bifidobacterium adolescentis L2-32 and Faecalibacterium prausnitzii A2-165 and their interaction (2014) (80)
Metabolic Engineering of the Morphology of Aspergillus oryzae by Altering Chitin Synthesis (2002) (80)
Comparative metabolic network analysis of two xylose fermenting recombinant Saccharomyces cerevisiae strains. (2005) (80)
Induction and repression of alpha-amylase production in batch and continuous cultures of Aspergillus oryzae. (1995) (79)
Systems biology in hepatology: approaches and applications (2018) (79)
Growth and product formation of Aspergillus oryzae during submerged cultivations: verification of a morphologically structured model using fluorescent probes. (1998) (79)
Fatty acid synthesis is required for breast cancer brain metastasis (2021) (78)
Genome-Scale Modeling of the Protein Secretory Machinery in Yeast (2013) (78)
Economic and environmental impacts of microbial biodiesel (2013) (77)
Metabolic engineering of the morphology of Aspergillus. (2001) (77)
Metabolic Control Analysis of the Penicillin Biosynthetic Pathway in a High‐Yielding Strain of Penicillium chrysogenum (1995) (77)
Yeast systems biology to unravel the network of life (2006) (76)
Efficient protein production by yeast requires global tuning of metabolism (2017) (76)
Systems Analysis Unfolds the Relationship between the Phosphoketolase Pathway and Growth in Aspergillus nidulans (2008) (76)
Surface Hydrophobicity of Aspergillus nidulans Conidiospores and Its Role in Pellet Formation (2003) (76)
Glucoamylase production in batch, chemostat and fed-batch cultivations by an industrial strain of Aspergillus niger (2000) (76)
Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress (2012) (76)
Nutritional systems biology: definitions and approaches. (2009) (76)
Cleanup and analysis of sugar phosphates in biological extracts by using solid-phase extraction and anion-exchange chromatography with pulsed amperometric detection. (1998) (76)
Evolutionary engineering reveals divergent paths when yeast is adapted to different acidic environments. (2017) (75)
Production of biopharmaceutical proteins by yeast Advances through metabolic engineering (2018) (75)
Transcription analysis using high-density micro-arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol. (2006) (74)
Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology (2020) (74)
Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae (2014) (74)
Alleviation of glucose repression of maltose metabolism by MIG1 disruption in Saccharomyces cerevisiae (1996) (74)
Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals (2017) (74)
Exploring the potential of Saccharomyces cerevisiae for biopharmaceutical protein production. (2017) (74)
Human metabolic atlas: an online resource for human metabolism (2015) (74)
Metabolic control analysis of biochemical pathways based on a thermokinetic description of reaction rates. (1997) (74)
On-line study of fungal morphology during submerged growth in a small flow-through cell. (1998) (74)
An expanded role for microbial physiology in metabolic engineering and functional genomics: moving towards systems biology. (2002) (74)
Structured modeling of a microbial system: I. A theoretical study of lactic acid fermentation (1991) (74)
Fungal metabolite analysis in genomics and phenomics. (2006) (73)
Identification of In Vivo Enzyme Activities in the Cometabolism of Glucose and Acetate by Saccharomyces cerevisiae by Using 13C-Labeled Substrates (2003) (73)
Evolution reveals a glutathione-dependent mechanism of 3-hydroxypropionic acid tolerance. (2014) (73)
Engineering of chromosomal wax ester synthase integrated Saccharomyces cerevisiae mutants for improved biosynthesis of fatty acid ethyl esters (2014) (73)
Elucidating the interactions between the human gut microbiota and its host through metabolic modeling (2014) (72)
Genome-scale modeling enables metabolic engineering of Saccharomyces cerevisiae for succinic acid production (2013) (72)
Influence of carbon source on α-amylase production by Aspergillus oryzae (2001) (71)
Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments (2007) (71)
Whole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications (2010) (71)
Engineering Robustness of Microbial Cell Factories (2017) (71)
Genome scale models of yeast: towards standardized evaluation and consistent omic integration. (2015) (70)
New paradigms for metabolic modeling of human cells. (2015) (70)
Analysis of flux estimates based on (13)C-labelling experiments. (2002) (70)
Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans (2006) (70)
Prospects for systems biology and modeling of the gut microbiome. (2011) (69)
Prospects of yeast systems biology for human health: integrating lipid, protein and energy metabolism. (2010) (69)
Engineering yeast metabolism for production of terpenoids for use as perfume ingredients, pharmaceuticals and biofuels. (2017) (69)
Energy metabolism controls phenotypes by protein efficiency and allocation (2019) (69)
Recent trends in metabolic engineering of microbial chemical factories. (2019) (68)
Metabolic Network Analysis (1999) (68)
Current Status of COVID-19 Therapies and Drug Repositioning Applications (2020) (68)
Identification of Enzymes and Quantification of Metabolic Fluxes in the Wild Type and in a Recombinant Aspergillus oryzae Strain (1999) (68)
Investigation of Malic Acid Production in Aspergillus oryzae under Nitrogen Starvation Conditions (2013) (68)
Expression of the Escherichia coli pntA andpntB Genes, Encoding Nicotinamide Nucleotide Transhydrogenase, in Saccharomyces cerevisiae and Its Effect on Product Formation during Anaerobic Glucose Fermentation (1999) (68)
Growth physiology and dimorphism of Mucor circinelloides (syn. racemosus) during submerged batch cultivation (2002) (68)
Polyol synthesis in Aspergillus niger: Influence of oxygen availability, carbon and nitrogen sources on the metabolism (2006) (67)
The human liver‐specific proteome defined by transcriptomics and antibody‐based profiling (2014) (67)
Fast and accurate preparation fatty acid methyl esters by microwave-assisted derivatization in the yeast Saccharomyces cerevisiae (2012) (67)
Physiological effects of nitrogen starvation in an anaerobic batch culture of Saccharomyces cerevisiae. (1996) (66)
Carbon catabolite repression of invertase during batch cultivations of Saccharomyces cerevisiae: the role of glucose, fructose, and mannose (1998) (66)
Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes. (2015) (66)
Metagenomic analysis of microbe-mediated vitamin metabolism in the human gut microbiome (2019) (66)
Enhancing the copy number of episomal plasmids in Saccharomyces cerevisiae for improved protein production. (2012) (66)
Modelling the growth of filamentous fungi. (1992) (65)
Biobased production of alkanes and alkenes through metabolic engineering of microorganisms (2016) (65)
Prediction of response to chemoradiation in rectal cancer by a gene polymorphism in the epidermal growth factor receptor promoter region. (2006) (64)
The Impact of Systems Biology on Bioprocessing. (2017) (64)
Multidimensional engineering of Saccharomyces cerevisiae for efficient synthesis of medium-chain fatty acids (2020) (63)
Scheffersomyces stipitis: a comparative systems biology study with the Crabtree positive yeast Saccharomyces cerevisiae (2012) (63)
Sampling and Sample Preparation (2006) (63)
Multiplexed CRISPR/Cas9 Genome Editing and Gene Regulation Using Csy4 in Saccharomyces cerevisiae. (2017) (63)
Yeast cell factories on the horizon (2015) (62)
Yeast mitochondria: an overview of mitochondrial biology and the potential of mitochondrial systems biology. (2018) (62)
Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative (2018) (61)
Current status of systems biology in Aspergilli. (2009) (61)
Enabling the synthesis of medium chain alkanes and 1-alkenes in yeast. (2017) (61)
Absolute yeast mitochondrial proteome quantification reveals trade-off between biosynthesis and energy generation during diauxic shift (2020) (61)
Production of β-ionone by combined expression of carotenogenic and plant CCD1 genes in Saccharomyces cerevisiae (2015) (61)
Deep learning suggests that gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure (2019) (60)
The Insulin-Like Growth Factor System and Markers of Inflammation in Adult Patients with Inflammatory Bowel Disease (2005) (60)
Molecular Mechanism of Flocculation Self-Recognition in Yeast and Its Role in Mating and Survival (2015) (60)
Engineering central metabolism – a grand challenge for plant biologists (2017) (60)
Proteome- and Transcriptome-Driven Reconstruction of the Human Myocyte Metabolic Network and Its Use for Identification of Markers for Diabetes. (2016) (60)
Do genome-scale models need exact solvers or clearer standards? (2015) (60)
Cocoa butter-like lipid production ability of non-oleaginous and oleaginous yeasts under nitrogen-limited culture conditions (2017) (60)
Defining the human adipose tissue proteome to reveal metabolic alterations in obesity. (2014) (60)
Transcription factor control of growth rate dependent genes in Saccharomyces cerevisiae: A three factor design (2008) (59)
Metabolic Network Analysis of Streptomyces tenebrarius, a Streptomyces Species with an Active Entner-Doudoroff Pathway (2005) (59)
In vivo dynamics of galactose metabolism in Saccharomyces cerevisiae: metabolic fluxes and metabolite levels. (2001) (59)
Affibody Scaffolds Improve Sesquiterpene Production in Saccharomyces cerevisiae. (2017) (59)
Physiological characterization of the high malic acid-producing Aspergillus oryzae strain 2103a-68 (2014) (58)
Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling (2015) (58)
Metagenomic Data Utilization and Analysis (MEDUSA) and Construction of a Global Gut Microbial Gene Catalogue (2014) (58)
Balanced globin protein expression and heme biosynthesis improve production of human hemoglobin in Saccharomyces cerevisiae. (2014) (57)
Global Transcriptional and Physiological Responses of Saccharomyces cerevisiae to Ammonium, l-Alanine, or l-Glutamine Limitation (2006) (57)
Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue (2015) (56)
On Local Optima in Learning Bayesian Networks (2002) (56)
Applications of computational modeling in metabolic engineering of yeast. (2014) (56)
The roles of galactitol, galactose‐1‐phosphate, and phosphoglucomutase in galactose‐induced toxicity in Saccharomyces cerevisiae (2008) (56)
Reconstruction and logical modeling of glucose repression signaling pathways in Saccharomyces cerevisiae (2009) (56)
Physiological studies in aerobic batch cultivations of Saccharomyces cerevisiae strains harboring the MEL1 gene (2000) (56)
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion (2018) (56)
It Is All about Metabolic Fluxes (2003) (56)
Structured modeling of a microbial system: II. Experimental verification of a structured lactic acid fermentation model (1991) (55)
Population balance models of autonomous microbial oscillations. (1995) (55)
Platelets and Anticoagulant Capacity in Patients with Inflammatory Bowel Disease (2002) (55)
Meta-analysis of the gut microbiota in predicting response to cancer immunotherapy in metastatic melanoma (2020) (55)
In Vivo Analysis of the Viable Microbiota and Helicobacter pylori Transcriptome in Gastric Infection and Early Stages of Carcinogenesis (2017) (55)
The impact of GAL6, GAL80, and MIG1 on glucose control of the GAL system in Saccharomyces cerevisiae. (2001) (55)
Identification and treatment of heme depletion attributed to overexpression of a lineage of evolved P450 monooxygenases (2012) (55)
Gut microbiota dysbiosis is associated with malnutrition and reduced plasma amino acid levels: Lessons from genome-scale metabolic modeling. (2018) (55)
Metabolic engineering of Saccharomyces cerevisiae for overproduction of triacylglycerols (2018) (55)
Continuous cultivation of Penicillium chrysogenum. Growth on glucose and penicillin production. (1995) (55)
Harnessing xylose pathways for biofuels production. (2019) (55)
Drug Repositioning for Effective Prostate Cancer Treatment (2018) (55)
Heterologous transporter expression for improved fatty alcohol secretion in yeast. (2018) (55)
Machine Learning Applied to Predicting Microorganism Growth Temperatures and Enzyme Catalytic Optima. (2019) (54)
Cancer Metabolism: A Modeling Perspective (2015) (54)
The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling (2015) (54)
Linking Genotype and Phenotype of Saccharomyces cerevisiae Strains Reveals Metabolic Engineering Targets and Leads to Triterpene Hyper-Producers (2011) (53)
Engineering the protein secretory pathway of Saccharomyces cerevisiae enables improved protein production (2018) (53)
Design and application of genome-scale reconstructed metabolic models. (2008) (53)
Adaptive laboratory evolution of tolerance to dicarboxylic acids in Saccharomyces cerevisiae. (2019) (53)
Quantitative analysis of Penicillium chrysogenum Wis54-1255 transformants overexpressing the penicillin biosynthetic genes. (2001) (53)
Molecular and process design for rotavirus-like particle production in Saccharomyces cerevisiae (2011) (53)
Metabolic Models of Protein Allocation Call for the Kinetome. (2017) (53)
Increased glycopeptide production after overexpression of shikimate pathway genes being part of the balhimycin biosynthetic gene cluster. (2010) (52)
Production of 3-hydroxypropionic acid from glucose and xylose by metabolically engineered Saccharomyces cerevisiae (2015) (52)
Optimization of heterologous production of the polyketide 6‐MSA in Saccharomyces cerevisiae (2007) (52)
Simplified Intestinal Microbiota to Study Microbe-Diet-Host Interactions in a Mouse Model (2019) (52)
Purification and characterization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Penicillium chrysogenum. (1997) (51)
Heat shock response improves heterologous protein secretion in Saccharomyces cerevisiae (2013) (51)
The yeast osmostress response is carbon source dependent (2017) (51)
Adaptation to different types of stress converge on mitochondrial metabolism (2016) (51)
Combinatorial, additive and dose-dependent drug–microbiome associations (2021) (51)
Transcriptome signatures in Helicobacter pylori-infected mucosa identifies acidic mammalian chitinase loss as a corpus atrophy marker (2013) (51)
Heterologous production of polyunsaturated fatty acids in Saccharomyces cerevisiae causes a global transcriptional response resulting in reduced proteasomal activity and increased oxidative stress. (2011) (50)
The role of metabolomics in systems biology (2007) (50)
A molecular genetic toolbox for Yarrowia lipolytica (2017) (50)
Adsorption and interfacial electron transfer of Saccharomyces cerevisiae yeast cytochrome c monolayers on Au(111) electrodes (2003) (50)
Metabolite secretion in microorganisms: the theory of metabolic overflow put to the test (2018) (50)
Hyperhomocysteinaemia, Coagulation Pathway Activation and Thrombophilia in Patients with Inflammatory Bowel Disease (2002) (50)
Epidermal growth factor receptor analyses in colorectal cancer: a comparison of methods. (2006) (49)
Aerobic glucose metabolism of Saccharomyces kluyveri: growth, metabolite production, and quantification of metabolic fluxes. (2002) (49)
Modeling fermentations with recombinant microorganisms: Formulation of a structured model (1991) (49)
Phenotypic characterization of glucose repression mutants of Saccharomyces cerevisiae using experiments with 13C‐labelled glucose (2004) (49)
High Temperature Co‐Electrolysis of Steam and CO2 in an SOC Stack: Performance and Durability (2013) (48)
Aerobic physiology of redox-engineered Saccharomyces cerevisiae strains modified in the ammonium assimilation for increased NADPH availability. (2003) (48)
Omega‐3 fatty acids inhibit an increase of proinflammatory cytokines in patients with active Crohn's disease compared with omega‐6 fatty acids (2005) (48)
Production of extracellular protease and glucose uptake in Bacillus clausii in steady-state and transient continuous cultures. (2002) (48)
Comparative Transcriptomic Approach To Investigate Differences in Wine Yeast Physiology and Metabolism during Fermentation (2009) (48)
Engineering 1-Alkene Biosynthesis and Secretion by Dynamic Regulation in Yeast. (2018) (47)
EasyCloneMulti: A Set of Vectors for Simultaneous and Multiple Genomic Integrations in Saccharomyces cerevisiae (2016) (47)
Metabolic network analysis of Bacillus clausii on minimal and semirich medium using (13)C-labeled glucose. (2002) (47)
Ontogeny and characterization of blood leukocyte subsets and serum proteins in piglets before and after weaning. (2010) (47)
4-Nitrothiophenol SAM on Au(111) Investigated by in Situ STM, Electrochemistry, and XPS (2001) (46)
Effect of carbon source perturbations on transcriptional regulation of metabolic fluxes in Saccharomyces cerevisiae (2007) (46)
Reconstruction and Evaluation of the Synthetic Bacterial MEP Pathway in Saccharomyces cerevisiae (2012) (46)
Branching is coordinated with mitosis in growing hyphae of Aspergillus nidulans. (2003) (46)
Improving the flux distributions simulated with genome-scale metabolic models of Saccharomyces cerevisiae (2016) (46)
New Challenges to Study Heterogeneity in Cancer Redox Metabolism (2017) (46)
TCSBN: a database of tissue and cancer specific biological networks (2017) (46)
Impact of transamination reactions and protein turnover on labeling dynamics in 13C‐labeling experiments (2004) (45)
Influence of the Dissolved Oxygen Concentration on the Penicillin Biosynthetic Pathway in Steady‐State Cultures of Penicillium chrysogenum (1997) (45)
Reconstruction of a bacterial isoprenoid biosynthetic pathway in Saccharomyces cerevisiae (2008) (45)
Serum Trefoil Factors in Patients with Inflammatory Bowel Disease (2006) (45)
BioMet Toolbox 2.0: genome-wide analysis of metabolism and omics data (2014) (44)
CreA influences the metabolic fluxes of Aspergillus nidulans during growth on glucose and xylose. (2005) (44)
A comparison of direct infusion MS and GC-MS for metabolic footprinting of yeast mutants. (2007) (44)
Aspergilli: Systems biology and industrial applications (2012) (44)
Biopharmaceutical protein production by Saccharomyces cerevisiae: current state and future prospects (2014) (44)
Galactose Expulsion during Lactose Metabolism in Lactococcus lactis subsp. cremoris FD1 Due to Dephosphorylation of Intracellular Galactose 6-Phosphate (1994) (44)
Moderate Expression of SEC16 Increases Protein Secretion by Saccharomyces cerevisiae (2017) (44)
Ach1 is involved in shuttling mitochondrial acetyl units for cytosolic C2 provision in Saccharomyces cerevisiae lacking pyruvate decarboxylase. (2015) (44)
Metabolic characterization of high- and low-yielding strains of Penicillium chrysogenum (2000) (44)
Production of the glycopeptide antibiotic A40926 by Nonomuraea sp. ATCC 39727: influence of medium composition in batch fermentation (2003) (44)
Systems biology based drug repositioning for development of cancer therapy. (2019) (43)
Genome‐scale metabolic model of Pichia pastoris with native and humanized glycosylation of recombinant proteins (2016) (43)
Novel insights into obesity and diabetes through genome-scale metabolic modeling (2013) (43)
Codon usage variability determines the correlation between proteome and transcriptome fold changes (2011) (43)
Morphology of Trichoderma reesei QM 9414 in submerged cultures (1995) (42)
Overexpression of isocitrate lyase-glyoxylate bypass influence on metabolism in Aspergillus niger. (2009) (42)
Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis (2009) (42)
Metabolic network analysis of an adipoyl-7-ADCA-producing strain of Penicillium chrysogenum: elucidation of adipate degradation. (2002) (42)
Changes of in vivo fluxes through central metabolic pathways during the production of nystatin by Streptomyces noursei in batch culture (2001) (42)
Changes in lipid metabolism convey acid tolerance in Saccharomyces cerevisiae (2018) (42)
Physiological characterization of recombinant Saccharomyces cerevisiae expressing the Aspergillus nidulans phosphoketolase pathway: validation of activity through 13C-based metabolic flux analysis (2012) (42)
Redirection of lipid flux toward phospholipids in yeast increases fatty acid turnover and secretion (2018) (42)
Comparison of the metabolic response to over-production of p-coumaric acid in two yeast strains. (2017) (42)
Glycosaminoglycan Profiling in Patients' Plasma and Urine Predicts the Occurrence of Metastatic Clear Cell Renal Cell Carcinoma. (2016) (41)
Aerobic and anaerobic ethanol production by Mucor circinelloides during submerged growth (2004) (41)
Correlation of cell growth and heterologous protein production by Saccharomyces cerevisiae (2013) (41)
A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome (2019) (41)
Heterologous production of non-ribosomal peptide LLD-ACV in Saccharomyces cerevisiae. (2009) (41)
Control of fluxes towards antibiotics and the role of primary metabolism in production of antibiotics. (2004) (41)
Dynamic regulation of fatty acid pools for improved production of fatty alcohols in Saccharomyces cerevisiae (2017) (41)
Metabolic engineering of beta-lactam production. (2003) (41)
Genome‐wide transcriptional response of a Saccharomyces cerevisiae strain with an altered redox metabolism (2004) (40)
Antisense Silencing of the creA Gene inAspergillus nidulans (2000) (40)
FANTOM: Functional and taxonomic analysis of metagenomes (2013) (40)
Bridging the gaps in systems biology (2014) (40)
Germline Polymorphisms may Act as Predictors of Response to Preoperative Chemoradiation in Locally Advanced T3 Rectal Tumors (2007) (40)
Engineering Saccharomyces cerevisiae cells for production of fatty acid-derived biofuels and chemicals (2019) (40)
Epidermal growth factor (EGF) A61G polymorphism and EGF gene expression in normal colon tissue from patients with colorectal cancer (2007) (40)
DPD is a molecular determinant of capecitabine efficacy in colorectal cancer. (2007) (40)
On-line study of growth kinetics of single hyphae of Aspergillus oryzae in a flow-through cell. (1999) (39)
Industrial systems biology and its impact on synthetic biology of yeast cell factories. (2016) (39)
Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 °C (2016) (39)
Mapping the polysaccharide degradation potential of Aspergillus niger (2012) (39)
Genome-wide analysis of maltose utilization and regulation in aspergilli. (2009) (39)
Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors (2018) (39)
Characterization of the Mucor circinelloides life cycle by on‐line image analysis (2003) (39)
Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes (2017) (39)
Microbiome and metabolome features of the cardiometabolic disease spectrum (2022) (39)
Role of substrate concentration in mitosis and hyphal extension of Aspergillus. (2000) (39)
The role of metabolic engineering in the production of secondary metabolites. (1998) (38)
Evolution from adherent to suspension: systems biology of HEK293 cell line development (2020) (38)
Study of the glucoamylase promoter in Aspergillus niger using green fluorescent protein. (1999) (38)
SLIMEr: probing flexibility of lipid metabolism in yeast with an improved constraint-based modeling framework (2018) (38)
Structured modeling of a microbial system: III. Growth on mixed substrates (1991) (38)
Physiology of Aspergillus niger in oxygen‐limited continuous cultures: Influence of aeration, carbon source concentration and dilution rate (2009) (38)
Management of the endoplasmic reticulum stress by activation of the heat shock response in yeast. (2014) (38)
In vitro co-cultures of human gut bacterial species as predicted from co-occurrence network analysis (2018) (38)
Metabolic pathway engineering for fatty acid ethyl ester production in Saccharomyces cerevisiae using stable chromosomal integration (2015) (38)
Nitrogen limitation reveals large reserves in metabolic and translational capacities of yeast (2020) (38)
Establishing very long‐chain fatty alcohol and wax ester biosynthesis in Saccharomyces cerevisiae (2017) (37)
Altering the expression of two chitin synthase genes differentially affects the growth and morphology of Aspergillus oryzae. (2002) (37)
Identification of the Entner–Doudoroff pathway in an antibiotic‐producing actinomycete species (2004) (37)
Identification of flux regulation coefficients from elementary flux modes: A systems biology tool for analysis of metabolic networks (2007) (37)
Systems biology of energy homeostasis in yeast. (2010) (36)
Sheep kidney pyruvate carboxylase. Studies on its activation by acetyl coenzyme A and characteristics of its acetyl coenzyme A independent reaction. (1972) (36)
Hap4 Is Not Essential for Activation of Respiration at Low Specific Growth Rates in Saccharomyces cerevisiae* (2006) (36)
Dysregulated signaling hubs of liver lipid metabolism reveal hepatocellular carcinoma pathogenesis (2016) (36)
A maternal diet of fatty fish reduces body fat of offspring compared with a maternal diet of beef and a post‐weaning diet of fish improves insulin sensitivity and lipid profile in adult C57BL/6 male mice (2013) (36)
The effect of CreA in glucose and xylose catabolism in Aspergillus nidulans (2004) (36)
Long Term Testing of Short Stacks with Solid Oxide Cells for Water Electrolysis (2011) (36)
Temporary CD8+ T-cell depletion in pigs does not exacerbate infection with porcine reproductive and respiratory syndrome virus (PRRSV). (2004) (36)
Screening of 2A peptides for polycistronic gene expression in yeast (2018) (36)
Learning probabilistic decision graphs (2006) (36)
Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp1p and Stp2p (2004) (36)
Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis (2020) (36)
Simulation of penicillin production in fed-batch cultivations using a morphologically structured model. (1997) (35)
Studies of the Production of Fungal Polyketides in Aspergillus nidulans by Using Systems Biology Tools (2009) (35)
RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae (2019) (35)
Genome scale metabolic modeling of the riboflavin overproducer Ashbya gossypii (2014) (34)
Leucine Biosynthesis Is Involved in Regulating High Lipid Accumulation in Yarrowia lipolytica (2017) (34)
Biosynthesis of glyoxylate from glycine in Saccharomyces cerevisiae. (2005) (34)
MEMOSys: Bioinformatics platform for genome-scale metabolic models (2011) (34)
FadR-based biosensor assisted screening for genes enhancing fatty acyl-CoA pools in Saccharomyces cerevisiae. (2019) (34)
Deep learning based kcat prediction enables improved enzyme constrained model reconstruction (2021) (34)
Functional expression and evaluation of heterologous phosphoketolases in Saccharomyces cerevisiae (2016) (34)
Metabolic network analysis on Phaffia rhodozyma yeast using 13C-labeled glucose and gas chromatography-mass spectrometry. (2004) (34)
Genetic and biological characterisation of an avian-like H1N2 swine influenza virus generated by reassortment of circulating avian-like H1N1 and H3N2 subtypes in Denmark (2013) (34)
Logical transformation of genome-scale metabolic models for gene level applications and analysis (2015) (33)
Integrative analysis of human omics data using biomolecular networks. (2016) (33)
Expanding the dynamic range of a transcription factor-based biosensor in Saccharomyces cerevisiae. (2019) (33)
α-Amylase production in recombinant Aspergillus oryzae during fed-batch and continuous cultivations (1998) (33)
Fungal genomics beyond Saccharomyces cerevisiae? (2003) (33)
De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories (2021) (33)
Understanding signaling in yeast: Insights from network analysis (2007) (33)
Gene deletion of cytosolic ATP: citrate lyase leads to altered organic acid production in Aspergillus niger (2009) (33)
The Translational Status of Cancer Liquid Biopsies (2019) (32)
Metabolic Control Analysis of Xylose Catabolism in Aspergillus (2008) (32)
Systems biology of industrial microorganisms. (2010) (32)
Purification and serological comparison of the yeast hexokinases P-I and P-II. (1973) (32)
Enhanced amino acid utilization sustains growth of cells lacking Snf1/AMPK. (2015) (32)
Lipase production by recombinant strains of Aspergillus niger expressing a lipase-encoding gene from Thermomyces lanuginosus (2004) (32)
Metagenomic analysis of bile salt biotransformation in the human gut microbiome (2019) (32)
Pathway kinetics and metabolic control analysis of a high‐yielding strain of Penicillium chrysogenum during fed batch cultivations (1996) (31)
Culture fluorescence measurements during batch and fed-batch cultivations with Penicillium chrysogenum (1994) (31)
Genome‐scale model of Rhodotorula toruloides metabolism (2019) (31)
Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis (2018) (31)
Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0 (2021) (31)
Identification of flux control in metabolic networks using non-equilibrium thermodynamics. (2010) (31)
Simple and robust method for estimation of the split between the oxidative pentose phosphate pathway and the Embden-Meyerhof-Parnas pathway in microorganisms. (2001) (31)
Metabolic engineering (2001) (31)
Current state of aromatics production using yeast: achievements and challenges. (2020) (31)
Elucidating aromatic acid tolerance at low pH in Saccharomyces cerevisiae using adaptive laboratory evolution (2020) (31)
Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3 (2009) (31)
Derepression of galactose metabolism in melibiase producing bakers' and distillers' yeast. (1999) (31)
Genome-scale analysis of the high-efficient protein secretion system of Aspergillus oryzae (2014) (31)
Perspective: Metabotyping—A Potential Personalized Nutrition Strategy for Precision Prevention of Cardiometabolic Disease (2019) (30)
Physiological characterization of xylose metabolism in Aspergillus niger under oxygen‐limited conditions (2007) (30)
Penicillium arizonense, a new, genome sequenced fungal species, reveals a high chemical diversity in secreted metabolites (2016) (30)
Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modeling (2013) (30)
Genome-scale metabolic network reconstruction of model animals as a platform for translational research (2021) (30)
Genome‐scale metabolic models applied to human health and disease (2017) (30)
The β‐subunits of the Snf1 kinase in Saccharomyces cerevisiae, Gal83 and Sip2, but not Sip1, are redundant in glucose derepression and regulation of sterol biosynthesis (2010) (30)
Physiological characterisation of Penicillium chrysogenum strains expressing the expandase gene from Streptomyces clavuligerus during batch cultivations. Growth and adipoyl-7-aminodeacetoxycephalosporanic acid production. (2001) (30)
Pathway kinetics and metabolic control analysis of a high-yielding strain of Penicillium chrysogenum during fed batch cultivations. (1996) (30)
Principles of optimal metabolic network operation (2007) (30)
An inclusion optimal algorithm for chain graph structure learning (2014) (30)
Anaerobic α-Amylase Production and Secretion with Fumarate as the Final Electron Acceptor in Saccharomyces cerevisiae (2013) (29)
Early pathogenesis of classical swine fever virus (CSFV) strains in Danish pigs. (2012) (29)
The yeast metabolome addressed by electrospray ionization mass spectrometry: Initiation of a mass spectral library and its applications for metabolic footprinting by direct infusion mass spectrometry (2008) (29)
Revealing the beneficial effect of protease supplementation to high gravity beer fermentations using "-omics" techniques (2011) (29)
Analysis of acyl CoA ester intermediates of the mevalonate pathway in Saccharomyces cerevisiae (2005) (29)
Mathematical models of cell factories: moving towards the core of industrial biotechnology (2011) (29)
Improved Production of a Heterologous Amylase in Saccharomyces cerevisiae by Inverse Metabolic Engineering (2014) (29)
Metabolic engineering of Saccharomyces cerevisiae for production of germacrene A, a precursor of beta-elemene (2017) (28)
Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipid production (2019) (28)
Metabolic control analysis of the penicillin biosynthetic pathway: the influence of the lld-ACV:bisACV ratio on the flux control (2004) (28)
Production of savinase and population viability of Bacillus clausii during high-cell-density fed-batch cultivations. (2003) (28)
Reconstruction and analysis of a Kluyveromyces marxianus genome-scale metabolic model (2019) (28)
Functional screening of aldehyde decarbonylases for long-chain alkane production by Saccharomyces cerevisiae (2017) (28)
Influence of carbon source on alpha-amylase production by Aspergillus oryzae. (2001) (28)
Strategies and challenges for metabolic rewiring (2019) (27)
Morphology and physiology of the dimorphic fungus Mucor circinelloides (syn. M. racemosus) during anaerobic growth. (2003) (27)
Use of laminar flow patterning for miniaturised biochemical assays. (2004) (27)
Modeling the mycelium morphology of Penicillium species in submerged cultures (1998) (27)
Proteome reallocation from amino acid biosynthesis to ribosomes enables yeast to grow faster in rich media (2020) (27)
Modeling the growth and proteinase A production in continuous cultures of recombinant Saccharomyces cerevisiae. (1997) (27)
α-Amylase production in high cell density submerged cultivation of Aspergillus oryzae and A. nidulans (2001) (27)
Human protein secretory pathway genes are expressed in a tissue-specific pattern to match processing demands of the secretome (2017) (27)
Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function. (2019) (27)
Metabolic Network-Based Identification and Prioritization of Anticancer Targets Based on Expression Data in Hepatocellular Carcinoma (2018) (27)
Production of Sustainable Fuels by Means of Solid Oxide Electrolysis (2011) (26)
Morphological characterization of recombinant strains of Aspergillus oryzae producing alpha-amylase during batch cultivations (1997) (26)
Morphological characterization of Aspergillus nidulans: growth, septation and fragmentation. (2001) (26)
The influence of microgravity on invasive growth in Saccharomyces cerevisiae. (2011) (26)
Engineering the oxygen sensing regulation results in an enhanced recombinant human hemoglobin production by Saccharomyces cerevisiae (2015) (26)
Combined Metabolic Activators Accelerates Recovery in Mild‐to‐Moderate COVID‐19 (2021) (26)
Elimination of the last reactions in ergosterol biosynthesis alters the resistance of Saccharomyces cerevisiae to multiple stresses (2017) (26)
When search engines become answer engines (2004) (26)
Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies (2021) (26)
Time course gene expression profiling of yeast spore germination reveals a network of transcription factors orchestrating the global response (2012) (26)
HCSD: the human cancer secretome database (2015) (26)
Model-assisted fine-tuning of central carbon metabolism in yeast through dCas9-based regulation. (2019) (26)
Rewiring Central Carbon Metabolism Ensures Increased Provision of Acetyl-CoA and NADPH Required for 3-OH-Propionic Acid Production. (2020) (25)
Cell factory engineering for improved production of natural products. (2019) (25)
Enhanced ethanol production and reduced glycerol formation in fps1∆ mutants of Saccharomyces cerevisiae engineered for improved redox balancing (2014) (25)
Machine learning applied to predicting microorganism growth temperatures and enzyme catalytic optima (2019) (25)
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism (2022) (25)
Thermodynamics of Metabolic Pathways for Penicillin Production: Analysis of Thermodynamic Feasibility and Free Energy Changes During Fed‐Batch Cultivation (1997) (25)
Pathway engineering in yeast for synthesizing the complex polyketide bikaverin (2019) (25)
Expression of cocoa genes in Saccharomyces cerevisiae improves cocoa butter production (2018) (25)
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non‐alcoholic fatty liver disease (2020) (25)
Systems Biology of Antibiotic Production by Microorganisms (2008) (25)
Pathway engineering in yeast for synthesizing the complex polyketide bikaverin (2019) (25)
Microbiome-derived ethanol in nonalcoholic fatty liver disease (2022) (24)
Adaptively evolved yeast mutants on galactose show trade-offs in carbon utilization on glucose. (2013) (24)
Metabolomics : a powerful tool in systems biology (2007) (24)
Increasing cocoa butter-like lipid production of Saccharomyces cerevisiae by expression of selected cocoa genes (2017) (24)
Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid–derived hydrocarbons (2018) (24)
Deletion of RTS1, Encoding a Regulatory Subunit of Protein Phosphatase 2A, Results in Constitutive Amino Acid Signaling via Increased Stp1p Processing (2006) (24)
Mathematical modeling of proteome constraints within metabolism (2021) (24)
Reconstruction of a Global Transcriptional Regulatory Network for Control of Lipid Metabolism in Yeast by Using Chromatin Immunoprecipitation with Lambda Exonuclease Digestion (2018) (24)
Regulation of Yeast-to-Hyphae Transition in Yarrowia lipolytica (2018) (24)
Substrate activation of pyruvate carboxylase by pyruvate. (1969) (24)
Silencing MIG1 in Saccharomyces cerevisiae: effects of antisense MIG1 expression and MIG1 gene disruption (1997) (24)
Physiological characterization of secondary metabolite producing Penicillium cell factories (2017) (23)
Bayesian genome scale modelling identifies thermal determinants of yeast metabolism (2020) (23)
Physiological characterisation of recombinant Aspergillus nidulans strains with different creA genotypes expressing A. oryzae alpha-amylase. (2002) (23)
CHAPTER 2 – Review of Cellular Metabolism (1998) (23)
Tackling Cancer with Yeast-Based Technologies. (2019) (23)
Controllability analysis of transcriptional regulatory networks reveals circular control patterns among transcription factors. (2015) (23)
Predicting growth of the healthy infant using a genome scale metabolic model (2017) (23)
Basic Biotechnology: Microbial process kinetics (2006) (23)
Application of genome-scale metabolic models in metabolic engineering (2013) (23)
Physiological characterization of secondary metabolite producing Penicillium cell factories (2017) (23)
A study on the applicability of implantable microchip transponders for body temperature measurements in pigs (2010) (23)
Complex I is bypassed during high intensity exercise (2019) (23)
Synthetic Biology of Yeast. (2019) (22)
Flux control through protein phosphorylation in yeast. (2016) (22)
Rewiring carbon flux in Escherichia coli using a bifunctional molecular switch. (2020) (22)
Impact of protein uptake and degradation on recombinant protein secretion in yeast (2014) (22)
Challenges in modeling the human gut microbiome (2018) (22)
Efficacy of marker vaccine candidate CP7_E2alf in piglets with maternally derived C-strain antibodies. (2012) (22)
Prognostic Value of Plasma and Urine Glycosaminoglycan Scores in Clear Cell Renal Cell Carcinoma (2016) (22)
How to set up collaborations between academia and industrial biotech companies (2015) (22)
Effect of deletion of chitin synthase genes on mycelial morphology and culture viscosity in Aspergillus oryzae. (2003) (22)
Integrated analysis, transcriptome-lipidome, reveals the effects of INO-level (INO2 and INO4) on lipid metabolism in yeast (2013) (22)
Genome-scale metabolic models of Saccharomyces cerevisiae. (2011) (22)
Integrative analysis using proteome and transcriptome data from yeast to unravel regulatory patterns at post‐transcriptional level (2010) (22)
Systematic Analysis Reveals that Cancer Mutations Converge on Deregulated Metabolism of Arachidonate and Xenobiotics. (2016) (22)
Two Uptake Systems for Fructose in Lactococcus lactis subsp. cremoris FD1 Produce Glycolytic and Gluconeogenic Fructose Phosphates and Induce Oscillations in Growth and Lactic Acid Formation (1993) (22)
Analysis of penicillin V biosynthesis during fed-batch cultivations with a high-yielding strain of Penicillium chrysogenum (1995) (22)
Industrial glucoamylase fed‐batch benefits from oxygen limitation and high osmolarity (2012) (22)
Identifying Molecular Effects of Diet through Systems Biology: Influence of Herring Diet on Sterol Metabolism and Protein Turnover in Mice (2010) (22)
Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter‐like lipids (2018) (21)
RNA-seq analysis of Pichia anomala reveals important mechanisms required for survival at low pH (2015) (21)
Systems biology analysis of hepatitis C virus infection reveals the role of copy number increases in regions of chromosome 1q in hepatocellular carcinoma metabolism. (2016) (21)
New insight into the gut microbiome through metagenomics (2015) (21)
Recovery of Phenotypes Obtained by Adaptive Evolution through Inverse Metabolic Engineering (2012) (21)
Anomeric specificity of glucose uptake systems in Lactococcus cremoris, Escherichia coli, and Saccharomyces cerevisiae: Mechanism, kinetics, and lmplications (1992) (21)
Examination for a viral co-factor in postweaning multisystemic wasting syndrome (PMWS) (2007) (21)
Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae (2017) (21)
Recombinant bacterial hemoglobin alters metabolism of Aspergillus niger. (2009) (21)
Novel UV Initiator for Functionalization of Multiwalled Carbon Nanotubes by Atom Transfer Radical Polymerization Applied on Two Different Grades of Nanotubes (2010) (21)
Glucose metabolism in the antibiotic producing actinomycete Nonomuraea sp. ATCC 39727. (2004) (21)
Steady-state and transient-state analyses of aerobic fermentation in Saccharomyces kluyveri. (2002) (21)
Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae (2005) (21)
Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae (2019) (21)
Durability Testing of a High‐Temperature Steam Electrolyzer Stack at 700 °C (2014) (21)
Kinetic studies on the carboxylation of 6-amino-penicillanic acid to 8-hydroxy-penillic acid (1997) (20)
Dynamic 13C-labeling experiments prove important differences in protein turnover rate between two Saccharomyces cerevisiae strains. (2012) (20)
Comprehensive understanding of Saccharomyces cerevisiae phenotypes with whole‐cell model WM_S288C (2020) (20)
Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipid production (2019) (20)
Modelling of the protonophoric uncoupling by phenoxyacetic acid of the plasma membrane potential of Penicillium chrysogenum. (1998) (20)
Gas–Liquid Mass Transfer (2011) (20)
Genome-Wide Mapping of Binding Sites Reveals Multiple Biological Functions of the Transcription Factor Cst6p in Saccharomyces cerevisiae (2016) (20)
Advancing biotechnology with CRISPR/Cas9: recent applications and patent landscape (2018) (20)
Degradation of pencillin‐V in fermentation media (1994) (20)
Specific growth rate and substrate dependent polyhydroxybutyrate production in Saccharomyces cerevisiae (2013) (20)
Dynamic Metabolic Footprinting Reveals the Key Components of Metabolic Network in Yeast Saccharomyces cerevisiae (2014) (20)
Integrated analysis of transcriptome and lipid profiling reveals the co-influences of inositol–choline and Snf1 in controlling lipid biosynthesis in yeast (2012) (20)
The impact of respiration and oxidative stress response on recombinant α-amylase production by Saccharomyces cerevisiae (2016) (20)
Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose (2019) (20)
Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels (2013) (19)
Stress-induced expression is enriched for evolutionarily young genes in diverse budding yeasts (2019) (19)
Plasma Glycosaminoglycans as Diagnostic and Prognostic Biomarkers in Surgically Treated Renal Cell Carcinoma (2018) (19)
Supervised classification using probabilistic decision graphs (2009) (19)
Systems biology perspective for studying the gut microbiota in human physiology and liver diseases (2019) (19)
Integrated analysis of the global transcriptional response to α‐amylase over‐production by Aspergillus oryzae (2011) (19)
A universal fixation method based on quaternary ammonium salts (RNAlater) for omics-technologies: Saccharomyces cerevisiae as a case study (2013) (19)
Purification Efficiency of Danish Biological Sand Filter Systems (1993) (19)
Improved production of fatty acids by Saccharomyces cerevisiae through screening a cDNA library from the oleaginous yeast Yarrowia lipolytica. (2016) (19)
Engineering carboxylic acid reductase for selective synthesis of medium-chain fatty alcohols in yeast (2020) (19)
In silico analysis of human metabolism: Reconstruction, contextualization and application of genome-scale models (2017) (19)
Mapping Condition-Dependent Regulation of Lipid Metabolism in Saccharomyces cerevisiae (2013) (19)
Elucidation of the role of Grr1p in glucose sensing by Saccharomyces cerevisiae through genome-wide transcription analysis. (2004) (19)
Semi-on-line analysis for fast and precise monitoring of bioreaction processes. (2000) (19)
Improved quantification of farnesene during microbial production from Saccharomyces cerevisiae in two-liquid-phase fermentations. (2016) (19)
Functional pyruvate formate lyase pathway expressed with two different electron donors in Saccharomyces cerevisiae at aerobic growth. (2015) (18)
In vivo assessment of the efficacy of an innovative face care system in subjects with mild acne vulgaris 1 (2004) (18)
Structural and transcriptional analysis of the pyrABCN, pyrD and pyrF genes in Aspergillus nidulans and the evolutionary origin of fungal dihydroorotases (1999) (18)
iNetModels 2.0: an interactive visualization and database of multi-omics data (2019) (18)
A systems biology approach to understand gut microbiota and host metabolism in morbid obesity: design of the BARIA Longitudinal Cohort Study (2020) (18)
Adaptive mutations in sugar metabolism restore growth on glucose in a pyruvate decarboxylase negative yeast strain (2015) (18)
Pyruvate decarboxylases from the petite-negative yeast Saccharomyces kluyveri (2003) (18)
Engineering lipid droplet assembly mechanisms for improved triacylglycerol accumulation in Saccharomyces cerevisiae (2018) (18)
Predictive models of eukaryotic transcriptional regulation reveals changes in transcription factor roles and promoter usage between metabolic conditions (2019) (18)
Glucose and maltose metabolism in MIG1-disrupted and MAL-constitutive strains of Saccharomyces cerevisiae (1997) (18)
Promiscuous phosphoketolase and metabolic rewiring enables novel non-oxidative glycolysis in yeast for high-yield production of acetyl-CoA derived products. (2020) (18)
Evidence, through C13-labelling analysis, of phosphoketolase activity in fungi (2007) (18)
Compartment model concept used in the design of fermentation with recombinant microorganisms (1989) (18)
Defining the human gallbladder proteome by transcriptomics and affinity proteomics (2014) (18)
Purification and properties of a novel nucleotide-hydrolysing enzyme (5'-nucleotidase) from Boophilus microplus. (1989) (18)
Proteome constraints reveal targets for improving microbial fitness in nutrient‐rich environments (2020) (18)
Production of β‐carotene in Saccharomyces cerevisiae through altering yeast lipid metabolism (2021) (17)
Lack of the type III epidermal growth factor receptor mutation in colorectal cancer. (2006) (17)
Optimizing cultivation of Cordyceps militaris for fast growth and cordycepin overproduction using rational design of synthetic media (2019) (17)
Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast (2018) (17)
Implementation of communication-mediating domains for non-ribosomal peptide production in Saccharomyces cerevisiae. (2010) (17)
Unraveling Molecular Signatures of Immunostimulatory Adjuvants in the Female Genital Tract through Systems Biology (2011) (17)
Building blocks are synthesized on demand during the yeast cell cycle (2020) (17)
Functional Characterization of a Porcine Emphysema Model (2013) (17)
Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Growth yields and morphological characterization. (2003) (17)
Genome‐scale metabolic representation of Amycolatopsis balhimycina (2012) (17)
Molecular factors of 5-fluorouracil metabolism in colorectal cancer: analysis of primary tumor and lymph node metastasis. (2006) (17)
Genome-scale model of Rhodotorula toruloides metabolism (2019) (17)
Increasing jojoba-like wax ester production in Saccharomyces cerevisiae by enhancing very long-chain, monounsaturated fatty acid synthesis (2019) (17)
Metabolomics in Humans and Other Mammals (2006) (17)
Identification of the decumbenone biosynthetic gene cluster in Penicillium decumbens and the importance for production of calbistrin (2018) (16)
In vitro turnover numbers do not reflect in vivo activities of yeast enzymes (2021) (16)
Improving heterologous protein secretion at aerobic conditions by activating hypoxia-induced genes in Saccharomyces cerevisiae. (2015) (16)
Anticancer drug discovery through genome-scale metabolic modeling (2017) (16)
Enabling technologies to advance microbial isoprenoid production. (2015) (16)
Protein kinase A is involved in the control of morphology and branching during aerobic growth of Mucor circinelloides. (2004) (16)
Transient Marker System for Iterative Gene Targeting of a Prototrophic Fungus (2007) (16)
Metabolic Engineering of Saccharomyces cerevisiae for Rosmarinic Acid Production (2020) (16)
Adaptive Evolution of Phosphorus Metabolism in Prochlorococcus (2016) (16)
Expanded metabolite coverage of Saccharomyces cerevisiae extract through improved chloroform/methanol extraction and tert-butyldimethylsilyl derivatization (2015) (16)
Advances in Metabolic Engineering of Saccharomyces cerevisiae for Cocoa Butter Equivalent Production (2020) (16)
Industrial antifoam agents impair ethanol fermentation and induce stress responses in yeast cells (2017) (16)
Pan-cancer analysis of the metabolic reaction network. (2019) (16)
Physiological characterization of glucose repression in the strains with SNF1 and SNF4 genes deleted. (2008) (16)
An improved FIA-system for measuring α-amylase in cultivation media (1994) (16)
Construction of mini‐chemostats for high‐throughput strain characterization (2019) (16)
Influence of the adipate and dissolved oxygen concentrations on the beta-lactam production during continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus. (2003) (15)
Improving the economics of NASH/NAFLD treatment through the use of systems biology. (2017) (15)
Selection of complementary foods based on optimal nutritional values (2017) (15)
Yeast optimizes metal utilization based on metabolic network and enzyme kinetics (2021) (15)
Learning Bayesian Networks for Regression from Incomplete Databases (2010) (15)
Metabolomics in Functional Genomics and Systems Biology (2006) (15)
The role of high-throughput transcriptome analysis in metabolic engineering (2005) (15)
A systems biology approach for studying neurodegenerative diseases. (2020) (15)
Metabolic network remodelling enhances yeast’s fitness on xylose using aerobic glycolysis (2021) (14)
Bioprospecting Through Cloning of Whole Natural Product Biosynthetic Gene Clusters (2020) (14)
Impact of Enteral Supplements Enriched with ω–3 Fatty Acids and/or ω–6 Fatty Acids, Arginine and Ribonucleic Acid Compounds on Leptin Levels and Nutritional Status in Active Crohn’s Disease Treated with Prednisolone (2007) (14)
Lipid biosynthesis monitored at the single‐cell level in Saccharomyces cerevisiae (2012) (14)
Six Tissue Transcriptomics Reveals Specific Immune Suppression in Spleen by Dietary Polyunsaturated Fatty Acids (2016) (14)
Microsatellite Instability and the Association with Plasma Homocysteine and Thymidylate Synthase in Colorectal Cancer (2008) (14)
NADPH-dependent glutamate dehydrogenase in Penicillium chrysogenum is involved in regulation of beta-lactam production. (2008) (14)
GROWTH AND ENZYME PRODUCTION DURING CONTINUOUS CULTURES OF A HIGH AMYLASE-PRODUCING VARIANT OF Aspergillus Oryzae (2002) (14)
Biotechnology for the future (2005) (14)
Translational and systems medicine (2012) (14)
Metabolic Alterations in Older Women With Low Bone Mineral Density Supplemented With Lactobacillus reuteri (2021) (13)
The simultaneous biosynthesis and uptake of amino acids by Lactococcus lactis studied by (13)C-labeling experiments. (2002) (13)
CHAPTER 4 – Material Balances and Data Consistency (1998) (13)
Steady-state and transient-state analyses of aerobic fermentation in (2002) (13)
CODY enables quantitatively spatiotemporal predictions on in vivo gut microbial variability induced by diet intervention (2021) (13)
Engineering yeast metabolism for the discovery and production of polyamines and polyamine analogues (2021) (13)
Phosphoglycerate mutase knock‐out mutant Saccharomyces cerevisiae: Physiological investigation and transcriptome analysis (2010) (13)
Physiological characterisation of acuB deletion in Aspergillus niger (2009) (13)
Quantifying absolute gene expression profiles reveals distinct regulation of central carbon metabolism genes in yeast (2020) (13)
Purification and characterization of δ-( L-α-aminoadipyl )-L-cysteinyl-D-valine synthetase from Penicillium chrysogenum (1997) (13)
Combined metabolic cofactor supplementation accelerates recovery in mild-to-moderate COVID-19 (2020) (13)
Yeast based biorefineries for oleochemical production. (2020) (13)
Identification of genes involved in shea butter biosynthesis from Vitellaria paradoxa fruits through transcriptomics and functional heterologous expression (2019) (13)
Scale-Up of Bioprocesses (2011) (13)
Proteome allocations change linearly with the specific growth rate of Saccharomyces cerevisiae under glucose limitation (2021) (13)
Immunohistochemical expression of thymidylate synthase as predictor of response to capecitabine in patients with advanced colorectal adenocarcinoma (2005) (13)
Sources of variation in cell-type RNA-Seq profiles (2020) (13)
Transcriptional control of metabolic fluxes (2011) (12)
Reconstruction of the yeast protein-protein interaction network involved in nutrient sensing and global metabolic regulation (2010) (12)
Emergence of stable coexistence in a complex microbial community through metabolic cooperation and spatio-temporal niche partitioning (2019) (12)
Yeast Biological Networks Unfold the Interplay of Antioxidants, Genome and Phenotype, and Reveal a Novel Regulator of the Oxidative Stress Response (2010) (12)
The human secretome – the proteins secreted from human cells (2018) (12)
Saccharomyces cerevisiae displays a stable transcription start site landscape in multiple conditions (2018) (12)
Reconstruction of 24 Penicillium genome‐scale metabolic models shows diversity based on their secondary metabolism (2018) (12)
Engineering yeast phospholipid metabolism for de novo oleoylethanolamide production (2019) (12)
Genome-Scale Metabolic Modeling from Yeast to Human Cell Models of Complex Diseases: Latest Advances and Challenges. (2019) (12)
Reconstruction of 24 Penicillium genome‐scale metabolic models shows diversity based on their secondary metabolism (2018) (12)
Multiscale models quantifying yeast physiology: towards a whole-cell model. (2021) (12)
Design of Fermentation Processes (2011) (12)
Comparative Transcriptome Analysis Shows Conserved Metabolic Regulation during Production of Secondary Metabolites in Filamentous Fungi (2019) (12)
Benchmarking accuracy and precision of intensity-based absolute quantification of protein abundances in Saccharomyces cerevisiae (2020) (12)
Kiwi: a tool for integration and visualization of network topology and gene-set analysis (2014) (12)
Combining Substrate Specificity Analysis with Support Vector Classifiers Reveals Feruloyl Esterase as a Phylogenetically Informative Protein Group (2010) (12)
Building a bio-based industry in the Middle East through harnessing the potential of the Red Sea biodiversity (2017) (12)
Metabolic engineering, synthetic biology and systems biology. (2012) (12)
Gcn4p and the Crabtree effect of yeast: drawing the causal model of the Crabtree effect in Saccharomyces cerevisiae and explaining evolutionary trade-offs of adaptation to galactose through systems biology. (2014) (12)
Chemicals from Metabolic Pathways (2011) (11)
Respiratory metabolism and calorie restriction relieve persistent endoplasmic reticulum stress induced by calcium shortage in yeast (2016) (11)
Genetically structured modeling of protein production in filamentous fungi. (1999) (11)
Production of teicoplanin by Actinoplanes teichomyceticus in continuous fermentation (2002) (11)
Expressing a cytosolic pyruvate dehydrogenase complex to increase free fatty acid production in Saccharomyces cerevisiae (2020) (11)
Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning (2020) (11)
Growth and Protein Formation of Recombinant Aspergillus: Utility of Morphological Characterization by Image Analysis (1994) (11)
Genetic and biological characterization of a Porcine Reproductive and Respiratory Syndrome Virus 2 (PRRSV-2) causing significant clinical disease in the field. (2017) (11)
In situ scanning probe microscopy and new perspectives in analytical chemistry (1999) (11)
Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients (2021) (11)
The pan-genome of Saccharomyces cerevisiae. (2019) (11)
Modular Pathway Rewiring of Yeast for Amino Acid Production. (2018) (11)
A novel yeast hybrid modeling framework integrating Boolean and enzyme-constrained networks enables exploration of the interplay between signaling and metabolism (2020) (11)
Disruption of the NADPH-dependent glutamate dehydrogenase affects the morphology of two industrial strains of Penicillium chrysogenum. (2009) (11)
Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretion (2021) (10)
A KINETIC MODEL FOR THE PENICILLIN BIOSYNTHETIC PATHWAY IN PENICILLIUM CHRYSOGENUM (1995) (10)
The future of genome-scale modeling of yeast through integration of a transcriptional regulatory network (2014) (10)
Finding directionality and gene-disease predictions in disease associations (2015) (10)
Insulin-like growth factors (IGFs) and IGF binding proteins in active Crohn's disease treated with omega-3 or omega-6 fatty acids and corticosteroids. (2005) (10)
Smakkerup Huse: A Mesolithic Settlement in NW Zealand, Denmark (2001) (10)
Teaching microbial physiology using glucose repression phenomenon in baker's yeast as an example (2005) (10)
High exogenous concentrations of phenoxyacetic acid are crucial for a high penicillin V productivity in Penicillium chrysogenum. (1998) (10)
Metabolic engineering of Saccharomyces cerevisiae microbial cell factories for succinic acid production (2007) (10)
Nitrogen-limited continuous cultivations as a tool to quantify glucose control in Saccharomyces cerevisiae (1998) (10)
Different Routes of Protein Folding Contribute to Improved Protein Production in Saccharomyces cerevisiae (2020) (10)
Physiological and transcriptional characterization of Saccharomyces cerevisiae engineered for production of fatty acid ethyl esters. (2016) (10)
Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Kinetics of adipoyl-7-aminodeacetoxycephalosporanic acid and byproduct formations. (2003) (10)
A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease (2021) (9)
Innovation trends in industrial biotechnology. (2022) (9)
ChIP-exo analysis highlights Fkh1 and Fkh2 transcription factors as hubs that integrate multi-scale networks in budding yeast (2019) (9)
Metabolic Engineering of Filamentous Fungi (2009) (9)
Integrated analysis of the yeast NADPH-regulator Stb5 reveals distinct differences in NADPH requirements and regulation in different states of yeast metabolism. (2018) (9)
High-Throughput Microfluidics for the Screening of Yeast Libraries. (2018) (9)
Expression of Thymidylate Synthase in Primary Colorectal Adenocarcinoma (2006) (9)
Reciprocal 13C‐Labeling: A Method for Investigating the Catabolism of Cosubstrates (2002) (9)
Identification and characterisation of two high-affinity glucose transporters from the spoilage yeast Brettanomyces bruxellensis (2019) (9)
Overpotential-induced lability of the electronic overlap factor in long-range electrochemical electron transfer: charge and distance dependence (2000) (9)
Selection and characterization of a high α-amylase-producing variant in glucose-limited continuous cultures of Aspergillus oryzae (2000) (8)
Chromosomal genome assembly of the ethanol production strain CBS 11270 indicates a highly dynamic genome structure in the yeast species Brettanomyces bruxellensis (2019) (8)
Genome-scale modeling drives 70-fold improvement of intracellular heme production in Saccharomyces cerevisiae (2022) (8)
Biofuels: chimeric synthetic pathways. (2011) (8)
Effects of overexpression of STB5 in Saccharomyces cerevisiae on fatty acid biosynthesis, physiology and transcriptome (2019) (8)
Carbohydrate active enzymes are affected by diet transition from milk to solid food in infant gut microbiota. (2019) (8)
Heme metabolism in stress regulation and protein production: From Cinderella to a key player (2016) (8)
Exploiting off‐targeting in guide‐RNAs for CRISPR systems for simultaneous editing of multiple genes (2017) (8)
Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers (2019) (8)
Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection (2021) (8)
Methane steam reforming kinetics over Ni-YSZ anodematerials for Solid Oxide FuelCells (2012) (8)
The Chemical Challenge of the Metabolome (2006) (8)
Phenotypic and genetic characterization of a novel phenotype in pigs characterized by juvenile hairlessness and age dependent emphysema (2008) (8)
Studies of On-line and In-situ Measuring Method for Biomass Concentration. (2000) (8)
Low S-adenosylmethionine concentrations found in patients with severe inflammatory bowel disease (2004) (8)
A kinetic model for the penicillin biosynthetic pathway in (1996) (7)
Integrated Metabolic Modeling, Culturing, and Transcriptomics Explain Enhanced Virulence of Vibrio cholerae during Coinfection with Enterotoxigenic Escherichia coli (2020) (7)
Big data in yeast systems biology. (2019) (7)
Systematic inference of functional phosphorylation events in yeast metabolism (2017) (7)
Thermodynamics of Bioreactions (2011) (7)
Unlocking the potential of fungi: the QuantFung project (2015) (7)
Identification and purification of O -acetyl-l-serine sulphhydrylase in Penicillium chrysogenum (1998) (7)
Classification of clear cell renal cell carcinoma based on PKM alternative splicing (2019) (7)
From Gene Expression to Metabolic Fluxes (2007) (7)
Modelling and inference with Conditional Gaussian Probabilistic Decision Graphs (2012) (7)
Editorial: The Impact of Systems Medicine on Human Health and Disease (2016) (7)
Mapping of Nonhomologous End Joining-Mediated Integration Facilitates Genome-Scale Trackable Mutagenesis in Yarrowia lipolytica. (2021) (7)
Production of a heterologous proteinase A by Saccharomyces kluyveri (2001) (7)
Transport of sugars via two anomer‐specific sites on mannose–phosphotransferase system in Lactococcus cremoris: In vivo study of mechanism, kinetics, and adaptation (1993) (7)
Methane Steam Reforming over an Ni-YSZ Solid Oxide Fuel Cell Anode in Stack Configuration (2014) (7)
Yeast functional genomics and metabolic engineering: past, present and future (2003) (7)
Addressing the heterogeneity in liver diseases using biological networks (2020) (7)
Combining laboratory and mathematical models to infer mechanisms underlying kinetic changes in macrophage susceptibility to an RNA virus (2016) (6)
Improving recombinant protein production by yeast through genome-scale modeling using proteome constraints (2022) (6)
An Empirical Study of Efficiency and Accuracy of Probabilistic Graphical Models (2006) (6)
Improvement in the Current Therapies for Hepatocellular Carcinoma Using a Systems Medicine Approach (2020) (6)
Biochemical Reaction Networks (2011) (6)
GTR 2.0: gRNA-tRNA Array and Cas9-NG Based Genome Disruption and Single-Nucleotide Conversion in Saccharomyces cerevisiae. (2021) (6)
Impact of forced fatty acid synthesis on metabolism and physiology of Saccharomyces cerevisiae. (2018) (6)
Systematic analysis of overall survival and interactions between tumor mutations and drug treatment (2016) (6)
The role of peroxisomes in xylose alcoholic fermentation in the engineered Saccharomyces cerevisiae (2020) (6)
Comparative genomics study reveals Red Sea Bacillus with characteristics associated with potential microbial cell factories (MCFs) (2019) (6)
Monolayers of a de novo designed 4-alpha-helix bundle carboprotein and partial structures on Au(111)-surfaces. (2002) (6)
Genetic Engineering Tools for Saccharomyces cerevisiae (2010) (6)
The integration of bio-catalysis and electrocatalysis to produce fuels and chemicals from carbon dioxide. (2022) (6)
Comparative metabolic capabilities for Micrococcus luteus NCTC 2665, the "Fleming" strain, and actinobacteria. (2011) (6)
Non-antibiotic treatment of equine endometritis (2018) (6)
Strategies and challenges with the microbial conversion of methanol to high‐value chemicals (2021) (6)
Kinetics of ?-amylase secretion inAspergillus oryzae (1999) (6)
Metabolic reconfiguration enables synthetic reductive metabolism in yeast (2022) (6)
ANT: Software for Generating and Evaluating Degenerate Codons for Natural and Expanded Genetic Codes. (2015) (6)
In search for symmetries in the metabolism of cancer (2016) (6)
Structural-EM for learning PDG models from incomplete data (2010) (6)
Description of the vibration generation mechanism of turnouts and the development of cost effective mitigation measures Deliverable D 3 . 6 (2013) (6)
The Reactobiome Unravels a New Paradigm in Human Gut Microbiome Metabolism (2021) (6)
Predictive engineering and optimization of tryptophan metabolism in yeast through a combination of mechanistic and machine learning models (2019) (6)
Metabolic profiling and compound-class identification reveal alterations in serum triglyceride levels in mice immunized with human vaccine adjuvant Alum. (2019) (6)
Trehalose-6-phosphate synthase and stabilization of yeast glycolysis. (2016) (6)
Mapping the interaction of Snf 1 with TORC 1 in Saccharomyces cerevisiae (2013) (5)
Yeast cells handle stress by reprogramming their metabolism (2019) (5)
Biosynthetic Studies of the Glycopeptide Teicoplanin by 1H and 13C NMR* (2000) (5)
Impact of systems biology on metabolic engineering (2014) (5)
Yeast Metabolomics: The Discovery of New Metabolic Pathways in Saccharomyces Cerevisiae (2006) (5)
The Glyoxylate-Serine Pathway Enables Conversion of Saccharomyces cerevisiae to a Synthetic Methylotroph (2021) (5)
Synthetic Biology Advanced Natural Product Discovery (2021) (5)
Global and temporal state of the human gut microbiome in health and disease (2021) (5)
Molecular natural history of breast cancer: Leveraging transcriptomics to predict breast cancer progression and aggressiveness (2020) (5)
Measurement of α-amylase activity by Sequential Injection Analysis (1995) (5)
Definition of wheel maintenance measures for reducing ground vibration Deliverable D 2 . 7 (2014) (5)
Microbial Metabolomics: Rapid Sampling Techniques to Investigate Intracellular Metabolite Dynamics—An Overview (2006) (5)
Bridging Omics Technologies with Synthetic Biology in Yeast Industrial Biotechnology (2012) (5)
Yeast has evolved to minimize protein resource cost for synthesizing amino acids (2022) (5)
Nanoscale and Single-Molecule Interfacial Electron Transfer (2003) (5)
Systems biology of microorganisms. (2010) (5)
Silencing MIG 1 in Saccharomyces cerevisiae : Effects of Antisense MIG 1 Expression and MIG 1 Gene Disruption (1997) (5)
RMetD2: a tool for integration of relative transcriptomics data into Genome-scale metabolic models (2019) (5)
Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning (2021) (5)
Organized Monolayers of Biological Macromolecules on Au(111) Surfaces (2002) (5)
Pan-cancer analysis of the metabolic reaction network (2016) (4)
A Chess-Computer Test Set (1991) (4)
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion (2020) (4)
Analysis of genome-wide coexpression and coevolution of Aspergillus oryzae and Aspergillus niger. (2010) (4)
The PDG-Mixture Model for Clustering (2009) (4)
Assembly and Analysis of the Genome Sequence of the Yeast Brettanomyces naardenensis CBS 7540 (2019) (4)
Revealing the Metabolic Alterations during Biofilm Development of Burkholderia cenocepacia Based on Genome-Scale Metabolic Modeling (2021) (4)
Exercise-Mediated Lowering of Glutamine Availability Suppresses Tumor Growth and Attenuates Muscle Wasting (2020) (4)
Hyperinsulinemia is Highly Associated with Markers of Hepatocytic Senescence in Two Independent Cohorts. (2022) (4)
Bayesian genome scale modelling identifies thermal determinants of yeast metabolism (2021) (4)
Elemental and Redox Balances (2011) (4)
Analytical performance of a standardized kit for mass spectrometry-based measurements of human glycosaminoglycans. (2021) (4)
Machine learning-based investigation of the cancer protein secretory pathway (2020) (4)
Growth Kinetics of Cell Cultures (2011) (4)
Combined Metabolic Activators Reduces Liver Fat in Nonalcoholic Fatty Liver Disease Patients (2021) (4)
Engineering yeast for high-level production of diterpenoid sclareol. (2022) (4)
Expression of fungal biosynthetic gene clusters in S. cerevisiae for natural product discovery (2021) (4)
A tool based on Bayesian networks for supporting geneticists in plant improvement by controlled pollination (2014) (4)
Evolution Reveals A Glutathione-dependent Mechanism Of 3-hydroxypropionic Acid Detoxification (2014) (4)
Author Correction: Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology (2020) (4)
Biochemical and physiological characterization of the efrotomycin fermentation (1991) (4)
A Caching Scheme to Accelerate Kinetic Monte Carlo Simulations of Catalytic Reactions. (2020) (4)
Genome-scale reconstruction of Corynebacterium glutamicum (2007) (4)
Mapping condition dependent regulation of lipid metabolism (2008) (4)
Penicillinase secretion in vivo and in vitro. (1983) (3)
Editorial: Industrial systems biology (2011) (3)
Qualification of flux control in metabolic pathways (2009) (3)
Quantification of Metabolic Fluxes (2003) (3)
Engineering the spatial organization of metabolic pathways (2009) (3)
Elucidating the mode-of-action of compounds from metabolite profiling studies. (2007) (3)
BUTTERFLY: addressing the pooled amplification paradox with unique molecular identifiers in single-cell RNA-seq (2021) (3)
One-year supplementation with Lactobacillus reuteri ATCC PTA 6475 counteracts a degradation of gut microbiota in older women with low bone mineral density (2022) (3)
Yeast systems biology in understanding principles of physiology underlying complex human diseases. (2019) (3)
Detection of any-stage cancer using plasma and urine glycosaminoglycans. (2021) (3)
Systems Biology: Developments and Applications (2014) (3)
Biochemical Reactions — A First Look (2003) (3)
CHAPTER 14 – Thermodynamics of Cellular Processes (1998) (3)
Production of Polyketides by Saccharomyces cerevisiae (2007) (3)
GotEnzymes: an extensive database of enzyme parameter predictions (2022) (3)
CHAPTER 10 – Applications of Metabolic Flux Analysis (1998) (3)
Biosynthesis of very long-chain fatty alcohols and wax esters in metabolically engineered strains of Saccharomyces cerevisiae (2016) (3)
Detection of endogenous beta-glucuronidase activity in Aspergillus niger. (1996) (3)
Genome-scale modeling of yeast metabolism: retrospectives and perspectives (2022) (3)
Detection of endogenous β-glucuronidase activity in Aspergillus niger (1996) (3)
Investigation of the impact of 1 and 2 on the physiology of (1999) (3)
Networking in metabolism and human disease (2015) (3)
Systems Biology of Metabolic Networks: Uncovering Regulatory and stoichiometric Principles (2007) (3)
Young Genes are More Responsive to Environmental Stress than Ancient Genes in Budding Yeasts (2019) (3)
Genome scale modeling of the protein secretory pathway reveals novel targets for improved recombinant protein production in yeast (2021) (3)
Diagnostik der Endeometritis beim Pferd – Mikrobiologie, Zytologie und Histologie von Endometriumsbiopsien und Korrelation mit der Fruchtbarkeit (2012) (2)
MEASURING TECHNIQUE AND FIELD DATA FOR PIPELINE STABILITY STUDIES (1987) (2)
Analytical Performance of a Standardized Kit for Mass Spectrometry-based Measurements of Human Glycosaminoglycans (2021) (2)
Transcriptomic response of Saccharomyces cerevisiae to octanoic acid production (2021) (2)
Harnessing synthetic biology for mushroom farming. (2022) (2)
planSOEC. R and D and commercialization roadmap for SOEC electrolysis. R and D of SOEC stacks with improved durability. Project report (2011) (2)
Maintaining a strong yeast research community. (2014) (2)
MOBN: an interactive database of multi-omics biological networks (2019) (2)
Systems biology methods and developments of filamentous fungi in relation to the production of food ingredients (2013) (2)
Metabolism: Built on stable catalysts (2017) (2)
Metabolomics: a powerful tool in systems biology: Topics in Current Genetics Series (2010) (2)
Kiwi: a tool for integration and visualization of network topology and gene-set analysis (2014) (2)
Quantitative in vivo evaluation of the reverse β-oxidation pathway for fatty acid production in Saccharomyces cerevisiae (2017) (2)
Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing (2020) (2)
Population Balance Equations (2011) (2)
Conditional Gaussian Probabilistic Decision Graphs (2010) (2)
A dedicated database system for handling multi-level data in systems biology (2014) (2)
Addressing the pooled amplification paradox with unique molecular identifiers in single-cell RNA-seq (2020) (2)
Systems biology: the 'new biotechnology'. (2012) (2)
Danish experiences after stopping the use of antibiotic growth promoters (2002) (2)
Author Correction: Fatty acid synthesis is required for breast cancer brain metastasis (2021) (2)
Clinical predictors of diarrhoea (2011) (2)
BUTTERFLY: addressing the pooled amplification paradox with unique molecular identifiers in single-cell RNA-seq (2021) (2)
Yeast systems biology. (2008) (2)
Mathematical Modelling of Microbial Processes-Motivation and Means (2001) (2)
Train Induced Ground Vibration – Influence of Rolling Stock State-ofthe-Art Survey Deliverable D 5 . 1 (2011) (2)
Metabolic engineering of Streptomyces (2009) (2)
Balanced globin protein expression and heme biosynthesis 1 improve production of human hemoglobin in Saccharomyces 2 cerevisiae 3 4 5 (2014) (2)
Production of a heterologous proteinase A by Saccharomyces kluyveri (2001) (2)
Supervised generative design of regulatory DNA for gene expression control (2021) (2)
Time course gene expression profiling of yeast spore germination reveals a network of transcription factors orchestrating the global response (2012) (2)
Exercise suppresses tumor growth through epinephrine- and IL-6-dependent mobilization and redistribution of NK cells (2015) (2)
Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism (2014) (2)
Cellular limitation of enzymatic capacity explains glutamine addiction in cancers (2022) (2)
FANTOM: Functional and taxonomic analysis of metagenomes (2013) (2)
Investigation of putative regulatory acetylation sites in Fas2p of Saccharomyces cerevisiae (2018) (2)
Coupling Cell Division to Metabolic Pathways Through Transcription (2019) (2)
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning (2022) (2)
Hyperhomocysteinemia, coagulation pathway activation and thrombophilia in inflammatory bowel disease (2002) (2)
Enhanced ethanol production and reduced glycerol formation in fps1∆ mutants of Saccharomyces cerevisiae engineered for improved redox balancing (2014) (2)
Chapter 2. Industrial Systems Biology (2010) (2)
Erratum to: A molecular genetic toolbox for Yarrowia lipolytica (2017) (2)
Production of "Green Natural Gas" Using Solid Oxide Electrolysis Cells (SOEC): Status of Technology and Costs (2012) (2)
Genome-scale insights into the metabolic versatility of Limosilactobacillus reuteri (2021) (2)
Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cells. (2022) (1)
Antibiotic Lethality Is Impacted by Nutrient Availabilities: New Insights from Machine Learning (2019) (1)
Building a bio-based industry in the Middle East through harnessing the potential of the Red Sea biodiversity (2017) (1)
Sealing glass for a electrolysis cell stacks of solid oxide (SOEC) (2010) (1)
What Is This Book About (2011) (1)
Machine learning for data integration in human gut microbiome (2022) (1)
Systems analysis of metabolic responses to a mixed meal test in an obese cohort reveals links between tissue metabolism and the gut microbiota (2022) (1)
Proteome Constraints in Genome‐Scale Models (2021) (1)
From the chief editor. The concept of scientific publication. (2013) (1)
Kinetics of alpha-amylase secretion in Aspergillus oryzae. (1999) (1)
The use of Genome-scale metabolic models for drug target and biomarker identification (2014) (1)
The impact of , , and on glucose control of the system in (2001) (1)
Establishment of Yeast Platform for Isoprenoid Production (2008) (1)
Integrative functional analysis uncovers metabolic differences between Candida species (2021) (1)
Transcriptome analysis of EPO and GFP HEK293 Cell-lines Reveal Shifts in Energy and ER Capacity Support Improved Erythropoietin Production in HEK293F Cells (2020) (1)
Penicillin Production in Fed-batch Cultures (1997) (1)
Transcriptome signatures in Helicobacter pylori-infected mucosa identifies acidic mammalian chitinase loss as a corpus atrophy marker (2013) (1)
Metastatic triple negative breast cancer adapts its metabolism to destination tissues while retaining key metabolic signatures (2022) (1)
A single chromosome strain of S. cerevisiae exhibits diminished ethanol metabolism and tolerance (2020) (1)
HyperHyper: developments across the field of hypermedia—a mini trip report (1989) (1)
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery (2022) (1)
Author Correction: A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism (2019) (1)
A network-based approach reveals the dysregulated transcriptional regulation in non-alcohol fatty liver disease (2021) (1)
Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress (2012) (1)
Physiological characterization of the high malic acid-producing Aspergillus oryzae strain 2103a-68 (2014) (1)
Evolution of the Metabolic Engineering Community. (2018) (1)
Structure and flux analysis of metabolic networks (2009) (1)
A systems biology approach to study non-alcoholic fatty liver (NAFL) in women with obesity (2022) (1)
Integrated analysis of transcriptome and lipid profiling reveals the co-influences of inositol–choline and Snf1 in controlling lipid biosynthesis in yeast (2012) (1)
The First International Workshop on Systems Biology of Yeast, St. Louis, USA, 9 November, 2003 (2004) (1)
Systems biology: Is the hope worth the hype (2008) (1)
Engineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiae (2012) (1)
The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling (2015) (1)
Human protein secretory pathway genes are expressed in a tissue-specific pattern to match processing demands of the secretome (2017) (1)
Metabolic Engineering of Yeast (2021) (1)
Droplet based directed evolution of yeast cell factories doubles production of industrial enzymes (2013) (1)
Identification of a novel gene required for competitive growth at high temperature in the thermotolerant yeast Kluyveromyces marxianus (2022) (1)
A bioinformatic pipeline to analyze ChIP-exo datasets (2019) (1)
Micro-droplet based directed evolution outperforms conventional laboratory evolution (2014) (1)
Fine-tuning of coumaric acid synthesis to increase naringenin production in yeast (2022) (1)
DSAVE: Detection of misclassified cells in single-cell RNA-Seq data (2020) (1)
FEMS yeast research: the yeast community journal. (2015) (1)
Amino acid and nucleotide metabolism shape the selection of trophic levels in animals (2021) (1)
Identification of Rate Controlling Enzymes in the Biosynthetic Pathway to Penicillin in a High Yielding Strain of Penicillium Chrysogenum (1992) (1)
Letter: Water intoxication and psychosis. (1974) (1)
Editorial Board: Biotechnology Journal 1/2016 (2016) (1)
Generation and analysis of context-specific genome-scale metabolic models derived from single-cell RNA-Seq data (2022) (1)
Organisation and Control of Nanoscale Structures on Au(111) (2001) (1)
Quantifying Extrusion Modification of LDPE with a Microcompounder (2012) (1)
Metabolic Engineering of Isoprenoid Production: Reconstruction of Multistep Heterologous Pathways in Tractable Hosts (2012) (1)
Metabolomics. Topics in Current Genetics (2008) (1)
PLOS Computational Biology 2017 Reviewer and Editorial Board Thank You (2018) (1)
Correction: Quantitative Analysis of Glycerol Accumulation, Glycolysis and Growth under Hyper Osmotic Stress (2014) (1)
Improving the internal flux distributions from genome scale metabolic models of S. cerevisiae (2014) (1)
Combined Metabolic Cofactor Supplementation Reduces Liver Fat in Nonalcoholic Fatty Liver Disease (2021) (1)
Data acquisition, analysis, and mining: Integrative tools for discerning metabolic function in Saccharomyces cerevisiae (2007) (1)
Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies (2022) (1)
Identification of the decumbenone biosynthetic gene cluster in Penicillium decumbens and the importance for production of calbistrin (2018) (0)
Efficient protein production by yeast requires global tuning of metabolism (2017) (0)
Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast (2018) (0)
A highly efficient transcriptome-based biosynthesis of non-ethanol chemicals in Crabtree negative Saccharomyces cerevisiae (2023) (0)
Functional expression and evaluation of heterologous phosphoketolases in Saccharomyces cerevisiae (2016) (0)
Specific growth rate and substrate dependent polyhydroxybutyrate production in Saccharomyces cerevisiae (2013) (0)
Metagenomic analysis of microbe-mediated vitamin metabolism in the human gut microbiome (2019) (0)
PREFACE (2019) (0)
A large-scale investigation of stress response mechanisms in the industrial yeast Kluyveromyces marxianus (2019) (0)
Author Correction: Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals (2018) (0)
Mathematical modeling of yeast : a driver for innovation in biotechnology and human medicine (2015) (0)
Type 2 diabetes is associated with increased circulating levels of 3-hydroxydecanoate activating GPR84 and neutrophil migration (2022) (0)
Heterologous production of nonribosomal peptides in Saccharomyces cerevisiae (2008) (0)
SUPPLEMENTARY MATERIAL AND METHODS (2017) (0)
Moderate overexpression of SEC16 improves alpha-Amylase secretion in Saccharomyes cerevisiae (2015) (0)
The yeastGemMap: A process diagram to assist yeast systems‐metabolic studies (2021) (0)
Editorial: Jurij Piškur (1960-2014). (2015) (0)
Directed evolution of a wax ester synthase for production of fatty acid ethyl esters in Saccharomyces cerevisiae (2023) (0)
Systems Biology of Saccharomyces cerevisiae Physiology and its DNA Damage Response (2010) (0)
Engineering Lipid Droplet Assembly Mechanisms for Improved Triacylglycerols Accumulation in S. cerevisiae (2018) (0)
Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative (2018) (0)
A universal fixation method based on quaternary ammonium salts (RNAlater) for omics-technologies: Saccharomyces cerevisiae as a case study (2013) (0)
In-depth analysis of Aspergillus niger metabolism during industrial fed-batch fermentations (2009) (0)
Metabollic Engineering of Saccharomyces Cereviae a,omi acid metabolism for production of products of industrial interest (2011) (0)
Integrated metabolic modeling, culturing and transcriptomics explains enhanced virulence of V. cholerae during co-infection with ETEC (2019) (0)
Editorial: Where is scientific publishing heading? (2017) (0)
A Pan-Draft Metabolic Model Reflects Evolutionary Diversity across 332 Yeast Species (2022) (0)
Heat shock response improves heterologous protein secretion in Saccharomyces cerevisiae (2012) (0)
Combined flow patterns in a stack of fuel cells or electrolysis cell stack (2010) (0)
standard-GEM: standardization of open-source genome-scale metabolic models (2023) (0)
Molecular Systems Biology CDK 2 i overcomes BRAFi-Hsp 90 i resistance (2018) (0)
Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries (2012) (0)
Development of SOEC Cells and Stacks: Highlights, Challenges and future Perspectives (2012) (0)
Development of SOEC Cells and Stacks (2012) (0)
Compression set, block fuel cell solid oxide, a method for compressing the fuel cell block solid oxide and their use (2007) (0)
Structural and transcriptional analysis of the pyrABCN, pyrD and pyrF genes in Aspergillus nidulans and the evolutionary origin of fungal dihydroorotases (2000) (0)
Metabolic Atlas – a website for exploration and visualization of metabolic networks (2020) (0)
Editorial: yeast synthetic biology. (2020) (0)
Glycosaminoglycan profiling in patients' plasma and urine predicts the occurrence of metastatic clear cell renal cell carcinoma. (2021) (0)
Building Aspergillus oryzae as an efficient cell factory for enzyme production (2008) (0)
RIVAS Railway Induced Vibration Abatement Solutions Collaborative project Train Induced Ground Vibration – Optimised Rolling Stock Mitigation Measures and the ir Parameters Deliverable D 5 . 4 (2013) (0)
Understanding the 3-hydroxypropionic acid tolerance mechanism in Saccharomyces cerevisiae (2013) (0)
Development of a yeast cell factory for production of aromatic products (2014) (0)
Nitrogen limitation reveals large reserves in metabolic and translational capacities of yeast (2020) (0)
Elucidating the biosynthetic pathway of the anticancer secondary metabolite calbistrin in Penicillium decumbens (2017) (0)
Clinical, Pathological and Immunological Aspects of Transplacental PRRS Virus Infection: Results from Danish Experiments (2011) (0)
Molecular characterization of a new porcine skin and lung phenotype: a potential model of human lung emphysema (2006) (0)
Electrochemistry of the blue copper protein Pseudomonas aeruginosa azurin (2001) (0)
Recovery of phenotypes obtained by adaptive evolution through inverse 1 metabolic engineering 2 3 (2012) (0)
Modular pathway rewiring enables L-ornithine production in engineered yeast (2015) (0)
METABOLIC PATHWAY ANALYSIS OF SACCHAROMYCES CEREVISIAE (2001) (0)
FALCONET: an R package to accelerate automatic visualisation of genome scale metabolic models (2019) (0)
Elucidating the biosynthetic pathway of the anticancer secondary metabolite calbistrin in Penicillium decumbens (2017) (0)
Global regulation of yeast metabolism (2015) (0)
Computational biology predicts metabolic engineering targets for increased production of 102 valuable chemicals in yeast (2023) (0)
Genome-Scale Metabolic Models: A Link between Bioinformatics and Systems Biology (2014) (0)
Mass Profiling of Fungal Extract from Penicillium Species (2006) (0)
Single-crystal electrochemistry and in situ scanning tunnelling microscopy of intermediate-size and large biomolecules (2001) (0)
Functional redox proteins on single-crystal gold electrodes: Some perspectives and puzzles. (2001) (0)
A systems medicine-based approach for finding metabolic targets applied to primary basal-like breast cancer. (2020) (0)
Insulin production in S. cerevisiae (2010) (0)
Zacros: Graph-Theoretical Kinetic Monte Carlo Software for Catalysis and Surface Science (2013) (0)
Title Yeast biological networks unfold the interplay of antioxidants , genome and phenotype , and reveal a novel regulator of the oxidative stress response (2010) (0)
Towards systems biomarkers for cancer diagnosis (2017) (0)
Wiley‐Interscience Series in Mass Spectrometry (2006) (0)
Promise and reality of systems biology in elucidating cellular behavior: Studying global regulation in yeast (2008) (0)
neering for improved production of natural products (2019) (0)
Integrated Metabolic Modeling, Culturing, and Transcriptomics Explain Enhanced Virulence of <named-content content-type='genus-species'>Vibrio cholerae</named-content> during Coinfection with Enterotoxigenic <named-content content-type='genus-species'>Escherichia coli</named-content> (2020) (0)
Physiological characterization of recombinant Saccharomyces cerevisiae expressing the Aspergillus nidulans phosphoketolase pathway: validation of activity through 13C-based metabolic flux analysis (2012) (0)
OptFlux: a software for metabolic engineering (2009) (0)
Applied systems biology - vanillin production in Saccharomyces cerevisiae (2012) (0)
Increased Stp 1 p Processing in Constitutive Amino Acid Signaling via ResultsSubunit of Protein Phosphatase 2 A , , Encoding a Regulatory RTS 1 Deletion of (2005) (0)
Automatic In-Vial MCF Derivatization Coupled to GC-MS for Simultaneous Determination of Amino and non-Amino Organic Acids (2004) (0)
Deciphering the tissue specificity of the protein secretory pathway in humans (2016) (0)
PLASMA GLYCOSAMINOGLYCAN SCORES IN RENAL CELL CARCINOMA: MP72‐19 (2018) (0)
Clinical characterization of a type 2 PRRSV causing significant clinical disease in the field in Denmark (2014) (0)
Most influential FEMS publications. (2014) (0)
Predicting growth of the healthy infant using a genome scale metabolic model (2017) (0)
Non-random organization of flux control mechanisms in yeast central metabolic pathways (2021) (0)
Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes (2017) (0)
The transcription factor Leu3 shows differential binding behavior in response to changing leucine availability (2020) (0)
Draft Genome Sequences of Five Fungal Strains Isolated from Kefir (2021) (0)
Analysis of Normal Levels of Urine and Plasma Free Glycosaminoglycans in Adults (2021) (0)
Engineering yeast metabolism for production of fuels and chemicals (2016) (0)
Why microbes will rule the world – and our industries (2017) (0)
Rational gRNA design based on transcription factor binding data (2021) (0)
Statistische Charakterisierung der Druckzonentiefe vorgespannter Gläser (2022) (0)
ATCC 1015 versus enzyme-producing CBS 513 . 88 Aspergillus niger Comparative genomics of citric-acid-producing Material Supplemental (2011) (0)
Amino acid and nucleotide metabolism 1 shape the selection of trophic levels in 2 animals 3 (2021) (0)
Verwendung von Polysacchariden zur Verbesserung der Lichtschutzwirkung kosmetischer oder dermatologischer Lichtschutzmittel (1997) (0)
Erhöhung der Stabilität von lecithin-und chitosanhaltigen Formulierungen durch Zusatz von Iminodibernsteinsäure (2001) (0)
Prediction of response to chemoradiation by a combination of genetic polymorphisms in locally advanced T3 rectal tumors (2007) (0)
Introduction The current drive to develop sustainable processes for the production of fuels and chemicals involves development of efficient cell factories through metabolic engineering (0)
En Route for Systems Biology: In Silico Pathway Analysis and Metabolite Profiling (2004) (0)
Prediction of response to chemoradiation in rectal cancer by gene polymorphism and plasma homocysteine (2005) (0)
Identification of genes involved in shea butter biosynthesis from Vitellaria paradoxa fruits through transcriptomics and functional heterologous expression (2019) (0)
An improved evolutionary algorithm-based framework for identifying in silico metabolic engineering targets (2006) (0)
Reconstruction and analysis of a Kluyveromyces marxianus genome-scale metabolic model (2019) (0)
Microbial cells for spermidine production (2018) (0)
Metabolic Engineering of Saccharomyces cerevisiae for Isoprenoid Production (2014) (0)
Yeast as a Platform Cell Factory in Future Biorefineries (2012) (0)
Microbial cell metabolically treated with an altered metabolite production. (1999) (0)
From glucose to antibiotics: what controls the fluxes? (2005) (0)
CHAPTER 9 – Methods for the Experimental Determination of Metabolic Fluxes by Isotope Labeling (1998) (0)
Production of engineered haemoglobin from yeast (2006) (0)
Yeast as a platform cell factory for production of fuels and chemicals (2010) (0)
A Network-Based Approach Reveals the Dysregulated Transcriptional Regulation in Non- Alcohol Fatty Liver Disease (2021) (0)
Abstracts of the 12 th European Congress on Biotechnology (2005) (0)
An integrative and probabilistic approach for discovering regulatory modules in molecular interaction networks (2005) (0)
Effect of the integration site on reporter gene expression in Saccharomyces cerevisiae (2007) (0)
Eukaryotic Polyketides in Surrogate Hosts (EUKETIDES). (2004) (0)
Recent trends in enzymes for pig production. (2000) (0)
Application of metabolic control analysis (MCA) on the enzymatic hydrolysis of model cellulose substrates (2005) (0)
Structural robustness of protein interaction networks are due to modularity (2005) (0)
Brain energy metabolism is optimized to minimize the cost of enzyme synthesis and transport (2022) (0)
Metabolic engineering of S. cerevisiae for overproduction of succinic acid (2006) (0)
Faculty Opinions recommendation of Viscous control of cellular respiration by membrane lipid composition. (2019) (0)
Correction to: Industrial antifoam agents impair ethanol fermentation and induce stress responses in yeast cells (2017) (0)
X-omics data for in depth understanding of polyketide production in Aspergillus nidulans (2007) (0)
Induction of gene expression by glucose in Saccharomyces kluyveri (2005) (0)
Bioproduction of Fuels: An Introduction (2017) (0)
Quantitative morphology of filamentous microorganisms. Chap.14 (1998) (0)
Random sampling of metabolic networks (2009) (0)
Author Correction: Metabolic reconfiguration enables synthetic reductive metabolism in yeast (2023) (0)
Metabolic engineering of succinic acid production in Saccharomyces cerevisiae (2005) (0)
Turnover Dependent Phenotypic Simulation: A Quantitative Constraint-Based Simulation Method That Accommodates All Main Strain Design Strategies. (2015) (0)
Central carbon metabolism in Saccharomyces cerevisiae: succinic acid production (2006) (0)
Process for production of terpenes and MEP transformed microorganisms for (2007) (0)
Aerobic and anaerobic cultivations of Aspergillus niger on different nitrogen sources (2005) (0)
Different roles of redundant beta subunits of Snf1 protein kinase in Saccharomyces cerevisiae (2008) (0)
Genome wide analysis of A. niger metabolism during industrial fed-batch fermentations (2009) (0)
Metabolic engineering frontiers emerging with advanced tools and methodologies. (2017) (0)
History and Present Status of Penicillin Production (1997) (0)
Model forms most useful (2017) (0)
Cocoa butter-like lipid production ability of non-oleaginous and oleaginous yeasts under nitrogen-limited culture conditions (2017) (0)
The influence of the LLD-ACV:bisACV ration on a MCA of the penicillin biosynthetic pathway in Penicillium chrysogenum (1998) (0)
Prediction of response to chemoradiation by a combination of genetic polymorphism in patinets with locally advanced T3 rectal tumours (2007) (0)
Characterization of cross-species transcription and splicing from Penicillium to Saccharomyces cerevisiae (2021) (0)
RIVAS Railway Induced Vibration Abatement Solutions Collaborative project Train Induced Ground Vibration – characterization of vehicle parameters from test data and simulations Deliverable D 5 . 2 (2012) (0)
Protein engineering of invertase for enhancing yeast dough fermentation under high-sucrose conditions (2022) (0)
Metabolite secretion in microorganisms: the theory of metabolic overflow put to the test (2018) (0)
System and method for transporting and inspecting a product intended for use in an offshore wind energy plant crane (2013) (0)
Wind Energy Development: Danish Experiences and International Options (1989) (0)
Editorial Board: Biotechnology Journal 1/2018 (2018) (0)
Editorial Board: Biotechnology Journal 1/2019 (2019) (0)
Yeast as a Prototype for Systems Biology (2009) (0)
Editorial Board: Biotechnology Journal 2/2019 (2019) (0)
The BioInnovation Institute as a catalyst for European life science startup creation (2022) (0)
Editorial Board: Biotechnology Journal 10/2017 (2017) (0)
Science 2015 Uhlen (2015) (0)
Systems Biology for Mapping Genotype-Phenotype Relations in Yeast (2016) (0)
Editorial Board: Biotechnology Journal 11/2015 (2015) (0)
Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery (2023) (0)
An Integrated Understand ing of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans Graphical (2018) (0)
Molecular determinants of capecitabine efficacy in colorectal cancer. (2006) (0)
Review: Computational Identification of Repeat-containing Proteins and Systems — R0/PR1 (2020) (0)
Faculty Opinions recommendation of Genome-Scale Architecture of Small Molecule Regulatory Networks and the Fundamental Trade-Off between Regulation and Enzymatic Activity. (2018) (0)
Automated reconstruction of tissue specific human metabolic networks and its potential impact on personalized medicine (2013) (0)
Leading Edge Previews Antibiotic Lethality Is Impacted by Nutrient Availabilities : New Insights fromMachine Learning (2019) (0)
Faculty Opinions recommendation of A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action. (2019) (0)
Multi-omics analyses of the transition to the Crabtree effect in S. cerevisiae reveals a key role for the citric acid shuttle. (2022) (0)
Enabling cell factory design through high-throughput and quantitative metabolome analysis (2005) (0)
The Impact of Systems Medicine on Human Health and Disease (2017) (0)
Additional file 1: of Metagenomic analysis of bile salt biotransformation in the human gut microbiome (2019) (0)
Faculty Opinions recommendation of Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT. (2018) (0)
A Comprehensive Dynamic Model of Gut Microbiome (2019) (0)
Metabolic collaboration between cells in the tumor microenvironment has a negligible effect on tumor growth (2022) (0)
towards modelling of the human gut microbiome 3 (2018) (0)
A Prochlorococcus proving ground for constraint-based metabolic modeling and multi-`omics data integration (2016) (0)
Production of fine chemicals by yeast and filamentous fungi (2008) (0)
Transcriptional progression of atrophic gastritis development in humans (2010) (0)
Exploring Biosynthetic Control in Lipid Metabolism (2006) (0)
TGFß1 signalling in human insulinomas compared with human islets. (2007) (0)
Regulation of type 1 interleukin-1 receptor expression in pancreatic islets in culture (1993) (0)
Dünnflüssige O/W-Emulsion und diese enthaltender Sprayapplikator (2004) (0)
Kosmetische und dermatologische Zubereitung zur Beseitigung und Regulation von Sebum (2001) (0)
W/S-Emulsionen und deren Verwendung (2001) (0)
Bedeutung und Aufmachung von Zusatzzertifikaten im Akkreditiv- und Garantiegeschäft (1993) (0)
Ascorbinsäurehaltige O/W-Emulsionen, diese enthaltende kosmetische und/oder dermatologische Zubereitungen, deren Verwendung sowie Verfahren zu ihrer Herstellung (2001) (0)
Verfahren zur Kaltemulgierung langzeitstabiler Emulsionen (2007) (0)
O/W-Emulsionen mit unpolaren Wirkstoffen, deren kosmetische und/oder dermatologische Zubereitungen und deren Verwendung (2001) (0)
Sonnenschutz mit hohem Triazingehalt (2014) (0)
Kosmetikum gegen Gesichtsglanz (2002) (0)
Wohlriechende kosmetische Zubereitung (2012) (0)
Verwendung von Cyclodextrinen zur Herstellung kosmetischer und dermatologischer Zubereitungen mit verbesserter Verteilbarkeit von Füllstoffen auf der Haut sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an Cyclodextrinen und Füllstoffen (2001) (0)
Professor Stefan Hohmann (08.09.1956–02.07.2021) (2022) (0)
Verwendung vo Hydroxypropylstärkephosphat in wirkstoffhaltigen kosmetischen Zubereitungen (2003) (0)
Kosmetische Zubereitung mit 1,2-Alkandiol(e) und Triazin(en) (2005) (0)
Verminderung der Rasurfrequenz durch Ketotriosen oder Tetrulosen (2009) (0)
Emulsion enthaltend 1,2-Alkandiole und polare Ölkomponenten (2005) (0)
Emulsion enthaltend 1,2-Alkandiole, Emulgatoren und polare Ölkomponenten sowie deren Verwendung (2005) (0)
Kosmetische Zubereitung mit sehr guten sensorischen Eigenschaften (2003) (0)
Klinische Bedeutung der Plazentaperforation und des blutigen Frucht-wassers für den Spontanabortus nach Amniozentese im 2. Trimenon (1987) (0)
Kosmetische oder dermatologische emulsionszubereitungen mit verbesserter parfumfreisetzung (2012) (0)
Kosmetische oder dermatologische peelingzubereitung (2012) (0)
Mikroemulsionen, Verfahren zu ihrer Herstellung und ihre Verwendung als Kosmetika (2007) (0)
Kosmetische Zubereitungen mit verminderter Transparenz und Klebrigkeit (2007) (0)
Verwendung von Cyclodextrinen zur Herstellung kosmetischer und dermatologischer Zubereitungen mit verbesserter Verteilbarkeit von anorganischen Pigmenten auf der Haut sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an Cyclodextrinen und anorganischen Pigmenten (2001) (0)
Kosmetische und/oder dermatologische Silikon-in Wasser-Emulsionen und transparentes Packmittel enthaltend diese Sonnenschutzzubereitungen (2002) (0)
Kosmetische gelförmige waschaktive zubereitung enthaltend 1,2-alkandiol(en) und ein oder mehrere polyacrylatverdicker (2006) (0)
2-Methyl-1,3-propandiol haltige Zubereitungen (2002) (0)
Kosmetische Zubereitungen mit naphthenarmen Mineralölen (2007) (0)
Management des klimakterischen Syndroms am Beispiel der Wechselambulanz der I. Universitäts-Frauenklinik (1987) (0)
Gefährdung der internationalen Anerkennung der von deutschen Banken ausgestellten Garantien (2004) (0)
KOSMETISCHE ODER PHARMAZEUTISCHE ZUBEREITUNGEN MIT VERMINDERTEM KLEBRIGKEITSGEFÜHL, ENTHALTEND GLYCERINESTER VON α-HYDROXYCARBONSÄUREN UND GESÄTTIGTEN FETTSÄUREN (1999) (0)
Kühlend wirkende kosmetische oder dermatologische Zusammensetzungen (1993) (0)
Learning Probabilistic Graphical Models: A Review of Techniques and Applications in Medicine (2012) (0)
Fast and accurate preparation fatty acid methyl esters by microwave-assisted derivatization in the yeast Saccharomyces cerevisiae (2012) (0)
Railway bridge over Södertälje Canal, Sweden (2011) (0)
From the chief editor. (2012) (0)
Aalborg Universitet On local optima in learning bayesian networks (2003) (0)
RIVAS Railway Induced Vibration Abatement Solutions Collaborative project Guideline for Design of Vehicles Generating Reduced Ground Vibration Deliverable D 5 . 5 (2013) (0)
Physiological characterization of secondary metabolite producing Penicillium cell factories (2017) (0)
Metagenomic analysis of bile salt biotransformation in the human gut microbiome (2019) (0)
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis (2020) (0)
Increasing cocoa butter-like lipid production of Saccharomyces cerevisiae by expression of selected cocoa genes (2017) (0)
Barriers and opportunities in bio-based production of hydrocarbons (2018) (0)
Design, fabrication and construction of railway bridge over Södertälje canal (2009) (0)
A single chromosome strain of S. cerevisiae exhibits diminished ethanol metabolism and tolerance (2021) (0)
Stress-induced expression is enriched for evolutionarily young genes in diverse budding yeasts (2020) (0)
Dysregulated autophagy in muscle precursor cells from humans with type 2 diabetes (2019) (0)
Selection of complementary foods based on optimal nutritional values (2017) (0)
Identification of the decumbenone biosynthetic gene cluster in Penicillium decumbens and the importance for production of calbistrin (2018) (0)

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