Jeremy Kirk Nicholson
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Jeremy Kirk Nicholsonbiology Degrees
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Microbiology
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Biology
Jeremy Kirk Nicholson's Degrees
- PhD Microbiology Stanford University
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Jeremy Kirk Nicholson's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Host-Gut Microbiota Metabolic Interactions (2012) (3420)
- 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. (1999) (3346)
- Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts (2007) (1777)
- Metabonomics: a platform for studying drug toxicity and gene function (2002) (1762)
- Systems biology: Metabonomics (2008) (1608)
- OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification (2006) (1149)
- Symbiotic gut microbes modulate human metabolic phenotypes (2008) (1028)
- Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism (2003) (990)
- Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice (2006) (983)
- Human metabolic phenotype diversity and its association with diet and blood pressure (2008) (976)
- Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor (2013) (967)
- Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics (2002) (925)
- 750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma. (1995) (885)
- Impact of the gut microbiota on inflammation, obesity, and metabolic disease (2016) (873)
- Gut microorganisms, mammalian metabolism and personalized health care (2005) (861)
- Global metabolic profiling procedures for urine using UPLC–MS (2010) (799)
- Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets. (2005) (776)
- Pharmaco-metabonomic phenotyping and personalized drug treatment (2006) (765)
- Fat, Fiber and Cancer Risk in African Americans and Rural Africans (2015) (682)
- Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism (2009) (666)
- Metabolic Phenotyping in Health and Disease (2008) (665)
- Preparing for precision medicine. (2012) (604)
- Systemic gut microbial modulation of bile acid metabolism in host tissue compartments (2010) (600)
- Gut microbiome-host interactions in health and disease (2011) (568)
- Global metabolic profiling of animal and human tissues via UPLC-MS (2012) (549)
- HIGH RESOLUTION PROTON MAGNETIC RESONANCE SPECTROSCOPY OF BIOLOGICAL FLUIDS (1989) (543)
- Gut microbiota modulation of chemotherapy efficacy and toxicity (2017) (541)
- Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies. (2005) (538)
- Improved WATERGATE Pulse Sequences for Solvent Suppression in NMR Spectroscopy (1998) (499)
- Scaling and normalization effects in NMR spectroscopic metabonomic data sets. (2006) (473)
- Intraoperative Tissue Identification Using Rapid Evaporative Ionization Mass Spectrometry (2013) (468)
- A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model (2007) (463)
- Understanding the role of gut microbiome-host metabolic signal disruption in health and disease. (2011) (452)
- UPLC/MS(E); a new approach for generating molecular fragment information for biomarker structure elucidation. (2006) (448)
- Metabolic phenotyping in clinical and surgical environments (2012) (445)
- Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids (2000) (438)
- Gut microbiota: a potential new territory for drug targeting (2008) (436)
- NMR‐based metabonomic approaches for evaluating physiological influences on biofluid composition (2005) (432)
- Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis (2004) (428)
- Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS). (2009) (426)
- Metabolic surgery profoundly influences gut microbial–host metabolic cross-talk (2011) (421)
- Probiotic modulation of symbiotic gut microbial–host metabolic interactions in a humanized microbiome mouse model (2008) (421)
- Integrated metabonomic analysis of the multiorgan effects of hydrazine toxicity in the rat. (2005) (404)
- Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk. (2012) (398)
- Pattern recognition methods and applications in biomedical magnetic resonance (2001) (397)
- NMR Spectroscopy of Biofluids (1999) (378)
- High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. (2005) (378)
- Global systems biology, personalized medicine and molecular epidemiology (2006) (376)
- Precision high-throughput proton NMR spectroscopy of human urine, serum, and plasma for large-scale metabolic phenotyping. (2014) (370)
- Molecular Phenomics and Metagenomics of Hepatic Steatosis in Non-Diabetic Obese Women (2018) (364)
- Gut microbiome interactions with drug metabolism, efficacy, and toxicity. (2017) (363)
- Colonization-Induced Host-Gut Microbial Metabolic Interaction (2011) (361)
- Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project. (2003) (355)
- Susceptibility of human metabolic phenotypes to dietary modulation. (2006) (350)
- High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues (2010) (337)
- The challenges of modeling mammalian biocomplexity (2004) (330)
- Assessment of analytical reproducibility of 1H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP Study. (2006) (325)
- Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes (2008) (315)
- Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome. (2015) (306)
- An NMR‐based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse (2000) (304)
- The handbook of metabonomics and metabolomics (2007) (303)
- Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies. (2006) (299)
- Recursive segment-wise peak alignment of biological (1)h NMR spectra for improved metabolic biomarker recovery. (2009) (298)
- Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls. (2010) (297)
- Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics. (2008) (296)
- NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. (2008) (290)
- Metabolic Profiling of CSF: Evidence That Early Intervention May Impact on Disease Progression and Outcome in Schizophrenia (2006) (285)
- Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine. (1984) (281)
- Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity (2015) (275)
- Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children☆ (2015) (271)
- Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification. (2004) (270)
- Metabonomics in pharmaceutical R & D (2007) (265)
- Proton-nuclear-magnetic-resonance studies of serum, plasma and urine from fasting normal and diabetic subjects. (1984) (262)
- Chemometric models for toxicity classification based on NMR spectra of biofluids. (2000) (258)
- The footprints of gut microbial-mammalian co-metabolism. (2011) (257)
- Metabonomics Techniques and Applications to Pharmaceutical Research & Development (2006) (255)
- Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins. (1998) (253)
- The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements. (2005) (247)
- Analytical reproducibility in (1)H NMR-based metabonomic urinalysis. (2002) (247)
- Hippurate: the natural history of a mammalian-microbial cometabolite. (2013) (244)
- Top-down systems biology modeling of host metabotype-microbiome associations in obese rodents. (2009) (240)
- Optimized preprocessing of ultra-performance liquid chromatography/mass spectrometry urinary metabolic profiles for improved information recovery. (2011) (238)
- Different Levels of Polybrominated Diphenyl Ethers (PBDEs) and Chlorinated Compounds in Breast Milk from Two U.K. Regions (2004) (238)
- A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion. (2005) (235)
- High resolution 1H n.m.r. studies of vertebrate blood and plasma. (1983) (233)
- Metabolic profiling strategy for discovery of nutritional biomarkers: proline betaine as a marker of citrus consumption. (2010) (230)
- Metabonomic and microbiological analysis of the dynamic effect of vancomycin-induced gut microbiota modification in the mouse. (2008) (228)
- The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk (2017) (227)
- Global urinary metabolic profiling procedures using gas chromatography–mass spectrometry (2011) (226)
- An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy. (2003) (225)
- Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier (2017) (224)
- Impact of analytical bias in metabonomic studies of human blood serum and plasma. (2006) (223)
- NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats. (2003) (214)
- Therapeutic Modulation of Microbiota-Host Metabolic Interactions (2012) (207)
- Automatic data reduction and pattern recognition methods for analysis of 1H nuclear magnetic resonance spectra of human urine from normal and pathological states. (1994) (205)
- Use of relaxation-edited one-dimensional and two dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma. (2004) (204)
- Investigations into the biochemical effects of region-specific nephrotoxins. (1989) (202)
- Summary recommendations for standardization and reporting of metabolic analyses (2005) (198)
- Objective set of criteria for optimization of sample preparation procedures for ultra-high throughput untargeted blood plasma lipid profiling by ultra performance liquid chromatography-mass spectrometry. (2014) (198)
- The gut microbiota influences skeletal muscle mass and function in mice (2019) (192)
- Application of biofluid 1H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile. (2003) (186)
- Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension. (2003) (182)
- Cryogenic probe 13C NMR spectroscopy of urine for metabonomic studies. (2002) (181)
- Species variation in the fecal metabolome gives insight into differential gastrointestinal function. (2008) (179)
- Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS‐DA (2002) (179)
- Improved analysis of multivariate data by variable stability scaling: application to NMR-based metabolic profiling (2003) (178)
- NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach. (2001) (178)
- Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks. (2001) (173)
- Metabonomic investigations into hydrazine toxicity in the rat. (2001) (173)
- Assignment of resonances for ‘acute‐phase’ glycoproteins in high resolution proton NMR spectra of human blood plasma (1987) (173)
- Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin (2018) (172)
- Application of pattern recognition methods to the analysis and classification of toxicological data derived from proton nuclear magnetic resonance spectroscopy of urine. (1991) (172)
- Metabonomics and its role in drug development and disease diagnosis (2004) (172)
- Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial (2017) (167)
- Panorganismal gut microbiome-host metabolic crosstalk. (2009) (167)
- Urinary metabolic signatures of human adiposity (2015) (166)
- Human metabolic phenotypes link directly to specific dietary preferences in healthy individuals. (2007) (164)
- Combined HPLC, NMR spectroscopy, and ion-trap mass spectrometry with application to the detection and characterization of xenobiotic and endogenous metabolites in human urine. (1996) (164)
- So what's the deal with metabonomics? (2003) (163)
- Nuclear magnetic resonance spectroscopy and pattern recognition analysis of the biochemical processes associated with the progression of and recovery from nephrotoxic lesions in the rat induced by mercury(II) chloride and 2-bromoethanamine. (1992) (162)
- Investigations into biochemical changes due to diurnal variation and estrus cycle in female rats using high-resolution (1)H NMR spectroscopy of urine and pattern recognition. (2001) (161)
- Proton NMR spectra of urine as indicators of renal damage. Mercury-induced nephrotoxicity in rats. (1985) (159)
- Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS. (2010) (158)
- Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development. (2000) (156)
- Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach. (2007) (156)
- The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine (1998) (153)
- Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models (2007) (153)
- Human metabolic profiles are stably controlled by genetic and environmental variation (2011) (151)
- Bile acid profiling and quantification in biofluids using ultra-performance liquid chromatography tandem mass spectrometry. (2015) (151)
- Novel application of reversed-phase UPLC-oaTOF-MS for lipid analysis in complex biological mixtures: a new tool for lipidomics. (2007) (150)
- Metabonomics in ulcerative colitis: diagnostics, biomarker identification, and insight into the pathophysiology. (2010) (150)
- Untargeted UPLC-MS Profiling Pipeline to Expand Tissue Metabolome Coverage: Application to Cardiovascular Disease (2015) (150)
- Metabolic phenotyping and systems biology approaches to understanding metabolic syndrome and fatty liver disease. (2014) (149)
- 750 MHz 1H NMR spectroscopy characterisation of the complex metabolic pattern of urine from patients with inborn errors of metabolism: 2-hydroxyglutaric aciduria and maple syrup urine disease. (1997) (149)
- Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse. (2004) (148)
- NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate. (2002) (148)
- Application of chemometrics to the 1H NMR spectra of apple juices: discrimination between apple varieties (1998) (148)
- HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies. (2011) (147)
- Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery (2008) (144)
- Metabolic profiling of genetic disorders: a multitissue (1)H nuclear magnetic resonance spectroscopic and pattern recognition study into dystrophic tissue. (2001) (143)
- Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice. (2006) (142)
- Metabonomic deconvolution of embedded toxicity: application to thioacetamide hepato- and nephrotoxicity. (2005) (142)
- NMR-based metabonomic toxicity classification: hierarchical cluster analysis and k-nearest-neighbour approaches (2003) (141)
- Pattern recognition classification of the site of nephrotoxicity based on metabolic data derived from proton nuclear magnetic resonance spectra of urine. (1994) (140)
- Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease (2021) (140)
- Metabonomic investigations of aging and caloric restriction in a life-long dog study. (2007) (139)
- The evolution of partial least squares models and related chemometric approaches in metabonomics and metabolic phenotyping (2010) (138)
- Spectral profiles of cultured neuronal and glial cells derived from HRMAS 1H NMR spectroscopy (2002) (136)
- The comparison of plasma deproteinization methods for the detection of low-molecular-weight metabolites by (1)H nuclear magnetic resonance spectroscopy. (2002) (136)
- The human gut microbiome: Implications for future health care (2008) (135)
- Biofluid 1H NMR-based metabonomic techniques in nutrition research - metabolic effects of dietary isoflavones in humans. (2005) (134)
- Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues. (2003) (133)
- Urinary excretion of acetaminophen and its metabolites as studied by proton NMR spectroscopy. (1984) (133)
- Opening up the "Black Box": metabolic phenotyping and metabolome-wide association studies in epidemiology. (2010) (133)
- Dietary modulation of gut functional ecology studied by fecal metabonomics. (2010) (132)
- Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles. (2004) (131)
- Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death. (2003) (130)
- Cadmium and mercury nephrotoxicity (1983) (130)
- A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection (2011) (129)
- High-resolution diffusion and relaxation edited one- and two-dimensional 1H NMR spectroscopy of biological fluids. (1996) (129)
- Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat. (2006) (129)
- Global metabolic responses of mice to Trypanosoma brucei brucei infection (2008) (127)
- NMR spectroscopy as a novel approach to the monitoring of renal transplant function. (1993) (126)
- Stability and robustness of human metabolic phenotypes in response to sequential food challenges. (2012) (126)
- Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage (2016) (126)
- Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota (2018) (124)
- Pharmacometabonomics as an effector for personalized medicine. (2011) (123)
- Environmental Metabonomics: Applying Combination Biomarker Analysis in Earthworms at a Metal Contaminated Site (2004) (123)
- Robust data processing and normalization strategy for MALDI mass spectrometric imaging. (2012) (122)
- High-throughput 1H NMR-based metabolic analysis of human serum and urine for large-scale epidemiological studies: validation study. (2008) (121)
- Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by 1H NMR Spectroscopy in a Multilaboratory Trial. (2018) (120)
- Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity. (2004) (120)
- The role of gut microbiota in drug response. (2009) (118)
- Biochemical classification of kidney carcinoma biopsy samples using magic-angle-spinning 1H nuclear magnetic resonance spectroscopy. (1998) (118)
- Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer (2014) (118)
- Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice. (2006) (117)
- Optimized Sample Handling Strategy for Metabolic Profiling of Human Feces. (2016) (117)
- Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study. (2010) (117)
- Metabonomic assessment of toxicity of 4‐fluoroaniline, 3,5‐difluoroaniline and 2‐fluoro‐4‐methylaniline to the earthworm Eisenia veneta (rosa): Identification of new endogenous biomarkers (2002) (117)
- Melamine-Induced Renal Toxicity Is Mediated by the Gut Microbiota (2013) (116)
- Variation in antibiotic-induced microbial recolonization impacts on the host metabolic phenotypes of rats. (2011) (115)
- Metabolomic analysis of the consequences of cadmium exposure in Silene cucubalus cell cultures via 1H NMR spectroscopy and chemometrics. (2003) (115)
- Metabolic profiling and the metabolome-wide association study: significance level for biomarker identification. (2010) (113)
- Toxicological applications of magnetic resonance (2004) (113)
- A metabolic system-wide characterisation of the pig: a model for human physiology. (2011) (112)
- Experimental and analytical variation in human urine in 1H NMR spectroscopy-based metabolic phenotyping studies. (2007) (111)
- High-performance liquid chromatography coupled to high-field proton nuclear magnetic resonance spectroscopy: application to the urinary metabolites of ibuprofen. (1993) (110)
- Comparative metabonomics of differential hydrazine toxicity in the rat and mouse. (2005) (110)
- Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy. (2007) (109)
- Metabonomic studies on the physiological effects of acute and chronic psychological stress in Sprague-Dawley rats. (2007) (109)
- Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets. (2005) (107)
- Metabolomic strategy for the classification and quality control of phytomedicine: a case study of chamomile flower (Matricaria recutita L.). (2004) (107)
- Automatic reduction of NMR spectroscopic data for statistical and pattern recognition classification of samples. (1994) (106)
- Direct coupling of chromatographic separations to NMR spectroscopy (1996) (106)
- Phylometabonomic Patterns of Adaptation to High Fat Diet Feeding in Inbred Mice (2008) (106)
- High-resolution magic angle spinning (1)H NMR spectroscopy of intact liver and kidney: optimization of sample preparation procedures and biochemical stability of tissue during spectral acquisition. (2000) (106)
- Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry. (2015) (103)
- Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation. (2006) (103)
- Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection (2020) (103)
- Metabolic assessment of human liver transplants from biopsy samples at the donor and recipient stages using high-resolution magic angle spinning 1H NMR spectroscopy. (2005) (103)
- Application of orthogonal signal correction to minimise the effects of physical and biological variation in high resolution 1H NMR spectra of biofluids. (2002) (102)
- Application of NMR-based metabolomics to the investigation of salt stress in maize (Zea mays). (2011) (101)
- 1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication. (2013) (101)
- NMR spectroscopy based metabonomic studies on the comparative biochemistry of the kidney and urine of the bank vole (Clethrionomys glareolus), wood mouse (Apodemus sylvaticus), white toothed shrew (Crocidura suaveolens) and the laboratory rat. (2000) (100)
- Directly coupled HPLC-NMR and its application to drug metabolism. (1997) (100)
- Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model (2008) (98)
- Ultra high field NMR spectroscopic studies on human seminal fluid, seminal vesicle and prostatic secretions. (1994) (98)
- Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice (2007) (97)
- High-resolution magic angle spinning NMR spectroscopy: Application to biomedical studies (2009) (97)
- Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice (2019) (96)
- Comparative tissue distribution of mercury, cadmium and zinc in three species of pelagic seabirds (1979) (95)
- In vivo endoscopic tissue identification by rapid evaporative ionization mass spectrometry (REIMS). (2015) (95)
- An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver. (2004) (95)
- 1H NMR spectroscopy-based interventional metabolic phenotyping: a cohort study of rheumatoid arthritis patients. (2010) (95)
- High resolution magic angle spinning 1H nuclear magnetic resonance analysis of intact prostatic hyperplastic and tumour tissues (1998) (95)
- Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism (2016) (94)
- Metabonomics: systems biology in pharmaceutical research and development. (2004) (93)
- Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping. (2016) (93)
- Nephrocalcinosis (Enamel Renal Syndrome) Caused by Autosomal Recessive FAM20A Mutations (2013) (92)
- Evaluation of full-resolution J-resolved 1H NMR projections of biofluids for metabonomics information retrieval and biomarker identification. (2010) (92)
- Analysis of biological fluids using 600 MHz proton NMR spectroscopy: application of homonuclear two-dimensional J-resolved spectroscopy to urine and blood plasma for spectral simplification and assignment. (1993) (91)
- Hyperspectral visualization of mass spectrometry imaging data. (2013) (91)
- XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules (2018) (91)
- Integrated metabonomic analysis of bromobenzene-induced hepatotoxicity: novel induction of 5-oxoprolinosis. (2006) (90)
- Automatic alignment of individual peaks in large high-resolution spectral data sets. (2004) (90)
- Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease (2019) (89)
- Quantitative high resolution 1H NMR urinalysis studies on the biochemical effects of cadmium in the rat. (1989) (89)
- Effects of probiotic Lactobacillus paracasei treatment on the host gut tissue metabolic profiles probed via magic-angle-spinning NMR spectroscopy. (2007) (87)
- Gut microbiota modulate the metabolism of brown adipose tissue in mice. (2012) (87)
- Distinction between normal and renal cell carcinoma kidney cortical biopsy samples using pattern recognition of 1H magic angle spinning (MAS) NMR spectra (2000) (87)
- Metabolic phenotyping for monitoring surgical patients (2011) (87)
- Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome. (2014) (86)
- Earthworm species of the genus Eisenia can be phenotypically differentiated by metabolic profiling (2002) (86)
- Power Analysis and Sample Size Determination in Metabolic Phenotyping. (2016) (86)
- An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. (2006) (83)
- Measurement of biomolecular diffusion coefficients in blood plasma using two-dimensional 1H-1H diffusion-edited total-correlation NMR spectroscopy. (1997) (83)
- NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat. (2010) (82)
- Curve-fitting method for direct quantitation of compounds in complex biological mixtures using 1H NMR: application in metabonomic toxicology studies. (2005) (81)
- 1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of drug metabolites (xenometabolome) in epidemiological studies. (2008) (80)
- Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation. (2006) (80)
- Ultra performance liquid chromatography-mass spectrometry profiling of bile acid metabolites in biofluids: application to experimental toxicology studies. (2010) (80)
- A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife (2016) (80)
- 600 MHz 1H-NMR spectroscopy of human cerebrospinal fluid: effects of sample manipulation and assignment of resonances. (1993) (79)
- K-OPLS package: Kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space (2008) (78)
- The metabolome-wide association study: a new look at human disease risk factors. (2008) (77)
- Two-dimensional proton nuclear magnetic resonance "maps" of acetaminophen metabolites in human urine. (1985) (75)
- Subset optimization by reference matching (STORM): an optimized statistical approach for recovery of metabolic biomarker structural information from 1H NMR spectra of biofluids. (2012) (74)
- Topographical variation in metabolic signatures of human gastrointestinal biopsies revealed by high-resolution magic-angle spinning 1H NMR spectroscopy. (2007) (74)
- Statistical experimental design and partial least squares regression analysis of biofluid metabonomic nmr and clinical chemistry data for screening of adverse drug effects (2004) (74)
- Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance (2017) (74)
- The influence of EDTA and citrate anticoagulant addition to human plasma on information recovery from NMR-based metabolic profiling studies. (2010) (74)
- Experimental metabonomic model of dietary variation and stress interactions. (2006) (73)
- The emergent role of metabolic phenotyping in dynamic patient stratification (2014) (73)
- How has healthcare research performance been assessed? A systematic review (2011) (73)
- Metabolite Changes in BT4C Rat Gliomas Undergoing Ganciclovir-Thymidine Kinase Gene Therapy-induced Programmed Cell Death as Studied by 1H NMR Spectroscopy in Vivo, ex Vivo, and in Vitro* (2003) (72)
- System level metabolic effects of a Schistosoma japonicum infection in the Syrian hamster. (2006) (72)
- Toxicity classification from metabonomic data using a density superposition approach: ‘CLOUDS’ (2003) (72)
- Global metabolic responses of NMRI mice to an experimental Plasmodium berghei infection. (2008) (72)
- Probing latent biomarker signatures and in vivo pathway activity in experimental disease states via statistical total correlation spectroscopy (STOCSY) of biofluids: application to HgCl2 toxicity. (2006) (70)
- Metabolic shifts due to long-term caloric restriction revealed in nonhuman primates (2009) (70)
- Statistical spectroscopic tools for biomarker discovery and systems medicine. (2013) (70)
- Experimental Bariatric Surgery in Rats Generates a Cytotoxic Chemical Environment in the Gut Contents (2011) (69)
- Directly coupled high-performance liquid chromatography and nuclear magnetic resonance spectroscopic with chemometric studies on metabolic variation in Sprague--Dawley rats. (2001) (69)
- Statistical correlation and projection methods for improved information recovery from diffusion-edited NMR spectra of biological samples. (2007) (69)
- Rapid Diagnosis and Staging of Colorectal Cancer via High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HR-MAS NMR) Spectroscopy of Intact Tissue Biopsies (2014) (69)
- Cellular environment of metabolites and a metabonomic study of tamoxifen in endometrial cells using gradient high resolution magic angle spinning 1H NMR spectroscopy. (2003) (68)
- Multi-component metabolic classification of commercial feverfew preparations via high-field 1H-NMR spectroscopy and chemometrics. (2002) (68)
- Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans (2014) (68)
- Systemic Perturbations in Amine and Kynurenine Metabolism Associated with Acute SARS-CoV-2 Infection and Inflammatory Cytokine Responses (2021) (67)
- Deep learning and 3D-DESI imaging reveal the hidden metabolic heterogeneity of cancer† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc03738k Click here for additional data file. Click here for additional data file. Click here for additional data file. (2017) (67)
- Topographical variation in murine intestinal metabolic profiles in relation to microbiome speciation and functional ecological activity. (2009) (67)
- Global metabolic phenotyping in an experimental laparotomy model of surgical trauma. (2011) (67)
- Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics (2003) (66)
- Metabolic profiling of body fluids by proton NMR: Self‐poisoning episodes with paracetamol (acetaminophen) (1988) (66)
- Comparison of in vivo1H MRS of human brain tumours with1H HR-MAS spectroscopy of intact biopsy samples in vitro (1999) (66)
- Generation of ultrahigh peak capacity LC separations via elevated temperatures and high linear mobile-phase velocities. (2006) (66)
- MetaboNetworks, an interactive Matlab-based toolbox for creating, customizing and exploring sub-networks from KEGG (2013) (65)
- A metabonomic approach to the investigation of drug-induced phospholipidosis: an NMR spectroscopy and pattern recognition study (2000) (65)
- Magic Angle Spinning Proton Nuclear Magnetic Resonance Spectroscopic Analysis of Intact Kidney Tissue Samples (1997) (64)
- Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective. (2018) (64)
- Solid-phase extraction chromatography and nuclear magnetic resonance spectrometry for the identification and isolation of drug metabolites in urine. (1987) (64)
- Use of High-Field 1H NMR Spectroscopy for the Analysis of Liquid Foods (1996) (64)
- Kernel‐based orthogonal projections to latent structures (K‐OPLS) (2007) (64)
- Metabolic profiling of chronic cadmium exposure in the rat. (2001) (64)
- Metabolic phenotyping of atherosclerotic plaques reveals latent associations between free cholesterol and ceramide metabolism in atherogenesis. (2015) (63)
- A Metabolite Array Technology for Precision Medicine. (2021) (63)
- Peer Reviewed: So What’s the Deal with Metabonomics? (2003) (63)
- The effects of kisspeptin on β‐cell function, serum metabolites and appetite in humans (2018) (62)
- Directly coupled liquid chromatography with inductively coupled plasma mass spectrometry and orthogonal acceleration time-of-flight mass spectrometry for the identification of drug metabolites in urine: application to diclofenac using chlorine and sulfur detection. (2000) (61)
- Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy (2012) (61)
- Sexual dimorphism in urinary metabolite profiles of Han Wistar rats revealed by nuclear-magnetic-resonance-based metabonomics. (2005) (61)
- Early metabolic adaptation in C57BL/6 mice resistant to high fat diet induced weight gain involves an activation of mitochondrial oxidative pathways. (2013) (60)
- Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids (2020) (60)
- Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen. (2001) (60)
- Multivariate metabotyping of plasma predicts survival in patients with decompensated cirrhosis (2016) (60)
- Targeting the human genome-microbiome axis for drug discovery: inspirations from global systems biology and traditional Chinese medicine. (2012) (60)
- Classification of toxin-induced changes in 1H NMR spectra of urine using an artificial neural network. (1995) (60)
- The mechanism of galactosamine toxicity revisited; a metabonomic study. (2007) (59)
- Ethyl glucoside in human urine following dietary exposure: detection by 1H NMR spectroscopy as a result of metabonomic screening of humans. (2004) (59)
- Detection of in vivo biomarkers of phospholipidosis using NMR‐based metabonomic approaches (2001) (58)
- Coupling of HPLC with 19F- and 1H-NMR spectroscopy to investigate the human urinary excretion of flurbiprofen metabolites. (1993) (58)
- An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria (2003) (58)
- Temporal metabonomic modeling of l-arginine-induced exocrine pancreatitis. (2008) (58)
- Gut microbiome modulates the toxicity of hydrazine: a metabonomic study. (2009) (58)
- High-Speed Quantitative UPLC-MS Analysis of Multiple Amines in Human Plasma and Serum via Precolumn Derivatization with 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate: Application to Acetaminophen-Induced Liver Failure. (2017) (58)
- Metabotyping of Long-Lived Mice using 1H NMR Spectroscopy (2012) (57)
- Analysis of polar urinary metabolites for metabolic phenotyping using supercritical fluid chromatography and mass spectrometry (2016) (57)
- Biochemical characterization of rat intestine development using high-resolution magic-angle-spinning 1H NMR spectroscopy and multivariate data analysis. (2005) (57)
- Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome. (2007) (57)
- The initial pathogenesis of cadmium induced renal toxicity (2000) (56)
- Induction of 5-oxoprolinuria in the rat following chronic feeding with N-acetyl 4-aminophenol (paracetamol). (1993) (56)
- Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma—Application to Clinical and Epidemiology Cohorts (2019) (56)
- The promise of metabolic phenotyping in gastroenterology and hepatology (2015) (56)
- Metabolic phenotyping of nude and normal (Alpk:ApfCD, C57BL10J) mice. (2006) (55)
- Genetic algorithms for simultaneous variable and sample selection in metabonomics (2009) (55)
- High resolution 1H NMR spectroscopic studies on dynamic biochemical processes in incubated human seminal fluid samples. (1998) (55)
- Uroscopy in the 21st century: high-field NMR spectroscopy. (1997) (55)
- Sex-dependent effects on gut microbiota regulate hepatic carcinogenic outcomes (2017) (55)
- NMR-based metabonomic studies on the biochemical effects of commonly used drug carrier vehicles in the rat. (2002) (55)
- Intra- and inter-omic fusion of metabolic profiling data in a systems biology framework (2010) (54)
- Robust algorithms for automated chemical shift calibration of 1D 1H NMR spectra of blood serum. (2008) (54)
- Identifying unknown metabolites using NMR-based metabolic profiling techniques (2020) (54)
- High‐resolution magic‐angle‐spinning 1H NMR spectroscopy reveals different responses in choline‐containing metabolites upon gene therapy‐induced programmed cell death in rat brain glioma (2005) (53)
- Virtual chromatographic resolution enhancement in cryoflow LC-NMR experiments via statistical total correlation spectroscopy. (2007) (52)
- Optimization of human plasma 1H NMR spectroscopic data processing for high-throughput metabolic phenotyping studies and detection of insulin resistance related to type 2 diabetes. (2008) (52)
- Use of 1H NMR‐determined diffusion coefficients to characterize lipoprotein fractions in human blood plasma (2002) (52)
- The metabolite profiles of the obese population are gender-dependent. (2014) (52)
- NMR spectroscopy of human post mortem cerebrospinal fluid: Distinction of Alzheimer's disease from control using pattern recognition and statistics (1993) (52)
- Technical and biological variation in UPLC-MS-based untargeted metabolic profiling of liver extracts: application in an experimental toxicity study on galactosamine. (2011) (52)
- Analytic properties of statistical total correlation spectroscopy based information recovery in 1H NMR metabolic data sets. (2009) (52)
- Dietary minerals in the gastrointestinal tract: hydroxypolymerisation of aluminium is regulated by luminal mucins. (1999) (51)
- Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome (2021) (51)
- NMR-based metabonomic studies on the biochemical effects of epicatechin in the rat. (2003) (51)
- 1H NMR studies on protein binding of histidine, tyrosine and phenylalanine in blood plasma (1989) (51)
- 19F-NMR and directly coupled HPLC-NMR-MS investigations into the metabolism of 2-bromo-4-trifluoromethylaniline in rat: a urinary excretion balance study without the use of radiolabelling. (1998) (50)
- Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data. (2002) (50)
- Structural shifts of gut microbiota as surrogate endpoints for monitoring host health changes induced by carcinogen exposure. (2010) (49)
- Gastro-intestinal availability of aluminium from tea. (1993) (49)
- 113Cd NMR studies of reconstituted seven-cadmium metallothionein: evidence for structural flexibility. (1985) (49)
- Intra- and interlaboratory reproducibility of ultra performance liquid chromatography-time-of-flight mass spectrometry for urinary metabolic profiling. (2012) (48)
- Identification of metabolites in human hepatic bile using 800 MHz 1H NMR spectroscopy, HPLC-NMR/MS and UPLC-MS. (2009) (48)
- Analysis of time-related metabolic fluctuations induced by ethionine in the rat. (2007) (47)
- Microbial-mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations. (2013) (47)
- Ion mobility spectrometry combined with ultra performance liquid chromatography/mass spectrometry for metabolic phenotyping of urine: Effects of column length, gradient duration and ion mobility spectrometry on metabolite detection (2017) (47)
- Metabolic profiling of the effects of D-galactosamine in liver spheroids using (1)H NMR and MAS-NMR spectroscopy. (2002) (47)
- High‐resolution diffusion and relaxation‐edited magic angle spinning 1H NMR spectroscopy of intact liver tissue (2003) (47)
- 2-Furoylglycine as a Candidate Biomarker of Coffee Consumption. (2015) (47)
- A metabonomic investigation of hepatotoxicity using diffusion-edited 1H NMR spectroscopy of blood serum. (2003) (47)
- Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation. (2008) (46)
- Vitamin E deficiency and metabolic deficits in neuronal ceroid lipofuscinosis described by bioinformatics. (2002) (46)
- Systematic Evaluation of Extraction Methods for Multiplatform-Based Metabotyping: Application to the Fasciola hepatica Metabolome (2012) (46)
- Solid phase extraction chromatography and NMR spectroscopy (SPEC-NMR) for the rapid identification of drug metabolites in urine. (1988) (46)
- Directly coupled CZE-NMR and CEC-NMR spectroscopy for metabolite analysis: paracetamol metabolites in human urine. (1998) (46)
- Characterisation of impurities in bulk drug batches of fluticasone propionate using directly coupled HPLC-NMR spectroscopy and HPLC-MS. (1997) (46)
- High-performance liquid chromatography linked to inductively coupled plasma mass spectrometry and orthogonal acceleration time-of-flight mass spectrometry for the simultaneous detection and identification of metabolites of 2-bromo-4-trifluoromethyl. (2001) (46)
- Metabolic profiling of rodent biological fluids via 1H NMR spectroscopy using a 1 mm microlitre probe. (2002) (45)
- A comparison of quantitative NMR and radiolabelling studies of the metabolism and excretion of Statil (3-(4-bromo-2-fluorobenzyl)-4-oxo-3H-phthalazin-1-ylacetic acid) in the rat. (2002) (45)
- Statistical total correlation spectroscopy editing of 1H NMR spectra of biofluids: application to drug metabolite profile identification and enhanced information recovery. (2009) (45)
- Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylaniline in the rat using 19F-NMR spectroscopy and directly coupled HPLC-NMR-MS. (1999) (45)
- Application of directly coupled LC-NMR-MS to the structural elucidation of metabolites of the HIV-1 reverse-transcriptase inhibitor BW935U83. (2000) (45)
- High-resolution magic angle spinning 1H-NMR spectroscopy studies on the renal biochemistry in the bank vole (Clethrionomys glareolus) and the effects of arsenic (As3+) toxicity (2001) (45)
- Magic angle spinning NMR and 1H-31P heteronuclear statistical total correlation spectroscopy of intact human gut biopsies. (2008) (44)
- 1H NMR studies of urine during fasting: Excretion of ketone bodies and acetylcarnitine (1986) (44)
- An Analytical Pipeline for Quantitative Characterization of Dietary Intake: Application To Assess Grape Intake. (2016) (44)
- Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis. (2006) (44)
- Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status (2004) (44)
- Qualitative high field 1H-NMR spectroscopy for the characterization of endogenous metabolites in earthworms with biochemical biomarker potential (2005) (44)
- High resolution nuclear magnetic resonance spectroscopy of biological samples as an aid to drug development. (1987) (43)
- Biochemical characterisation of para-aminophenol-induced nephrotoxic lesions in the F344 rat (2004) (43)
- Bariatric surgery modulates circulating and cardiac metabolites. (2014) (43)
- Impurity profiling in bulk pharmaceutical batches using 19F NMR spectroscopy and distinction between monomeric and dimeric impurities by NMR-based diffusion measurements. (1999) (42)
- Data-driven approach for metabolite relationship recovery in biological 1H NMR data sets using iterative statistical total correlation spectroscopy. (2011) (42)
- The comparative distribution of zinc, cadmium and mercury in selected tissues of the herring gull (Larus argentatus). (1981) (42)
- Hepatotoxin-induced hypertaurinuria: a proton NMR study (2005) (42)
- Heteronuclear 1H-31P statistical total correlation NMR spectroscopy of intact liver for metabolic biomarker assignment: application to galactosamine-induced hepatotoxicity. (2007) (42)
- HPLC/1H NMR spectroscopic studies of the reactive alpha-1-O-acyl isomer formed during acyl migration of S-naproxen beta-1-O-acyl glucuronide. (2001) (42)
- Age and Microenvironment Outweigh Genetic Influence on the Zucker Rat Microbiome (2014) (42)
- Quantitative structure-metabolism relationships for substituted benzoic acids in the rat. Computational chemistry, NMR spectroscopy and pattern recognition studies. (1992) (41)
- Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor (2021) (41)
- Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition (2005) (41)
- The influence of pharmacogenetics on fatty liver disease in the wistar and kyoto rats: a combined transcriptomic and metabonomic study. (2007) (40)
- Development and Validation of a High-Throughput Ultrahigh-Performance Liquid Chromatography-Mass Spectrometry Approach for Screening of Oxylipins and Their Precursors. (2015) (40)
- Analysis of Drug–Protein Binding Using Nuclear MagneticResonance Based Molecular Diffusion Measurements (1997) (40)
- Integrated Cytokine and Metabolic Analysis of Pathological Responses to Parasite Exposure in Rodents (2010) (40)
- Bile UPLC‐MS fingerprinting and bile acid fluxes during human liver transplantation (2011) (40)
- Compartmentation of metabolism probed by [2- 13 C ]alanine: improved 13 C NMR sensitivity using a CryoProbe detects evidence of a glial metabolon (2003) (39)
- Application of directly coupled HPLC-NMR-MS/MS to the identification of metabolites of 5-trifluoromethylpyridone (2-hydroxy-5-trifluoromethylpyridine) in hydroponically grown plants. (2000) (39)
- Aspergillosis of the sphenoid sinus: presentation as a pituitary mass and postoperative gallium-67 imaging. (1996) (39)
- Direct observation of resolved intracellular and extracellular water signals in intact human red blood cells using 1H MAS NMR spectroscopy (1997) (39)
- Systems parasitology: effects of Fasciola hepatica on the neurochemical profile in the rat brain (2010) (39)
- Liquid chromatography-mass spectrometry methods for urinary biomarker detection in metabonomic studies with application to nutritional studies. (2009) (39)
- 1H NMR spectroscopic investigations of tissue metabolite biomarker response to Cu II exposure in terrestrial invertebrates: identification of free histidine as a novel biomarker of exposure to copper in earthworms (1997) (39)
- Comparative biochemistry and short-term starvation effects on the earthworms Eisenia veneta and Lumbricus terrestris studied by 1H NMR spectroscopy and pattern recognition (2001) (39)
- Mass spectrometrically detected directly coupled high performance liquid chromatography/nuclear magnetic resonance spectroscopy/mass spectrometry for the identification of xenobiotic metabolites in maize plants. (2000) (38)
- 750 MHz HPLC-NMR spectroscopic studies on the separation and characterization of the positional isomers of the glucuronides of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid. (1996) (38)
- On-flow identification of metabolites of paracetamol from human urine using directly coupled CZE–NMR and CEC–NMR spectroscopy (1998) (38)
- Integrated Analytical and Statistical Two-Dimensional Spectroscopy Strategy for Metabolite Identification: Application to Dietary Biomarkers (2017) (38)
- A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer. (2019) (38)
- Implementation of Molecular Phenotyping Approaches in the Personalized Surgical Patient Journey (2012) (38)
- NMR Spectroscopic Windows on the Systemic Effects of SARS-CoV-2 Infection on Plasma Lipoproteins and Metabolites in Relation to Circulating Cytokines. (2021) (38)
- NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues. (2007) (38)
- Panorganismal Metabolic Response Modeling of an Experimental Echinostoma caproni Infection in the Mouse (2009) (37)
- Identification of the Positional Isomers of 2-Fluorobenzoic acid 1-O-Acyl Glucuronide by Directly Coupled HPLC-NMR (1995) (37)
- Mass directed peak selection, an efficient method of drug metabolite identification using directly coupled liquid chromatography-mass spectrometry-nuclear magnetic resonance spectroscopy. (2000) (37)
- Flow Injection Proton Nuclear Magnetic Resonance Spectroscopy Combined With Pattern Recognition Methods: Implications for Rapid Structural Studies and High Throughput Biochemical Screening (1997) (37)
- High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: application to the metabolites of 4-bromoaniline. (2000) (37)
- Development of a Rapid Microbore Metabolic Profiling Ultraperformance Liquid Chromatography-Mass Spectrometry Approach for High-Throughput Phenotyping Studies. (2016) (37)
- Variation in gut microbiota strongly influences individual rodent phenotypes. (2005) (37)
- Neonatal environment exerts a sustained influence on the development of the intestinal microbiota and metabolic phenotype (2015) (37)
- Cluster analysis statistical spectroscopy using nuclear magnetic resonance generated metabolic data sets from perturbed biological systems. (2009) (37)
- 1H and 2H NMR spectroscopic studies on the metabolism and biochemical effects of 2-bromoethanamine in the rat. (1995) (37)
- Evaluation of high resolution magic-angle coil spinning NMR spectroscopy for metabolic profiling of nanoliter tissue biopsies. (2012) (36)
- Proton NMR Spectroscopic Studies on Tissue Extracts of Invertebrate Species with Pollution Indicator Potential (1997) (36)
- Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome (2021) (36)
- Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies. (2009) (36)
- Characterization of metabolic responses to healthy diets and association with blood pressure: application to the Optimal Macronutrient Intake Trial for Heart Health (OmniHeart), a randomized controlled study. (2018) (36)
- Immunologic analysis of intraocular mononuclear cell infiltrates in uveitis. (1984) (35)
- Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations (2012) (35)
- A prospective analysis of mucosal microbiome-metabonome interactions in colorectal cancer using a combined MAS 1HNMR and metataxonomic strategy (2017) (35)
- The microanatomy of the distal tubules, collecting tubules and collecting ducts of the starling kidney. (1982) (35)
- Optimization and Application of Direct Infusion Nanoelectrospray HRMS Method for Large-Scale Urinary Metabolic Phenotyping in Molecular Epidemiology (2017) (35)
- The gut microbiota as a target for improved surgical outcome and improved patient care. (2009) (34)
- Large-scale human metabolic phenotyping and molecular epidemiological studies via 1H NMR spectroscopy of urine: investigation of borate preservation. (2009) (34)
- Direct characterization of drug glucuronide isomers in human urine by HPLC-NMR spectroscopy: application to the positional isomers of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid glucuronide. (1996) (34)
- Chiral metabonomics: 1H NMR-based enantiospecific differentiation of metabolites in human urine via direct cosolvation with β-cyclodextrin. (2012) (34)
- Metabolism of 4-fluoroaniline and 4-fluorobiphenyl in the earthworm Eisenia veneta characterized by high-resolution NMR spectroscopy with directly coupled HPLC-NMR and HPLC-MS (2002) (34)
- A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics: the INTERMAP Study. (2012) (33)
- Exploration of the direct metabolic effects of mercury II chloride on the kidney of Sprague-Dawley rats using high-resolution magic angle spinning 1H NMR spectroscopy of intact tissue and pattern recognition. (2006) (33)
- Evaluation of metabolic variation in normal rat strains from a statistical analysis of 1H NMR spectra of urine. (2004) (33)
- High-Throughput Microbore UPLC-MS Metabolic Phenotyping of Urine for Large-Scale Epidemiology Studies. (2015) (33)
- Integrated metabonomic-proteomic analysis of an insect-bacterial symbiotic system. (2010) (33)
- Mechanistic aspects and novel biomarkers of responder and non-responder phenotypes in galactosamine-induced hepatitis. (2009) (33)
- Nuclear magnetic resonance (NMR) and quantitative structure–activity relationship (QSAR) studies on the transacylation reactivity of model 1β-O-acyl glucuronides. II: QSAR modelling of the reaction using both computational and experimental NMR parameters (2004) (33)
- 750-MHz directly coupled HPLC-NMR: Application for the sequential characterization of the positional isomers and anomers of 2-, 3-, and 4-fluorobenzoic acid glucuronides in equilibrium mixtures (1995) (33)
- NMR spectroscopic studies on the haemolymph of the tobacco hornworm, Manduca sexta: assignment of 1H and 13C NMR spectra (1999) (33)
- 19F and 1H magnetic resonance strategies for metabolic studies on fluorinated xenobiotics: application to flurbiprofen [2-(2-fluoro-4-biphenylyl)propionic acid]. (1990) (33)
- Chemometric analysis of biofluids following toxicant induced hepatotoxicity: A metabonomic approach to distinguish the effects of 1-naphthylisothiocyanate from its products (2005) (33)
- Studies of the biochemical toxicology of uranyl nitrate in the rat (2009) (33)
- Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response. (2012) (33)
- Pharmacometabonomic investigation of dynamic metabolic phenotypes associated with variability in response to galactosamine hepatotoxicity. (2012) (32)
- Liquid chromatography coupled with high-field proton NMR for profiling human urine for endogenous compounds and drug metabolites. (1992) (32)
- Degradation of 4-Fluorobiphenyl by Mycorrhizal Fungi as Determined by 19F Nuclear Magnetic Resonance Spectroscopy and 14C Radiolabelling Analysis (1999) (32)
- Metabolic phenotype-microRNA data fusion analysis of the systemic consequences of Roux-en-Y gastric bypass surgery (2015) (32)
- Kidney lesions in pelagic seabirds with high tissue levels of cadmium and mercury (2009) (32)
- Quantitative structure-metabolism relationships (QSMR) using computational chemistry: pattern recognition analysis and statistical prediction of phase II conjugation reactions of substituted benzoic acids in the rat. (1999) (31)
- Investigation of the human metabolism of antipyrine using coupled liquid chromatography and nuclear magnetic resonance spectroscopy of urine. (1993) (31)
- Gut microbiota: Dietary and social modulation of gut microbiota in the elderly (2012) (31)
- Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions. (2008) (31)
- Characterization of Metabolites in IntactStreptomyces citricolorCulture Supernatants Using High-Resolution Nuclear Magnetic Resonance and Directly Coupled High-Pressure Liquid Chromatography–Nuclear Magnetic Resonance Spectroscopy☆ (1999) (31)
- Internal temperature calibration for 1H NMR spectroscopy studies of blood plasma and other biofluids (1994) (31)
- High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat. (1995) (31)
- Measurement of Internal Acyl Migration Reaction Kinetics Using Directly Coupled HPLC-NMR: Application for the Positional Isomers of Synthetic (2-Fluorobenzoyl)-d-glucopyranuronic Acid. (1996) (31)
- A Two-Way Interaction between Methotrexate and the Gut Microbiota of Male Sprague–Dawley Rats (2020) (30)
- Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets. (2004) (30)
- Piecewise multivariate modelling of sequential metabolic profiling data (2008) (30)
- Bidirectional correlation of NMR and capillary electrophoresis fingerprints: a new approach to investigating Schistosoma mansoni infection in a mouse model. (2010) (30)
- A high resolution proton nuclear magnetic resonance approach to the study of hepatocyte and drug metabolism. Application to acetaminophen. (1985) (30)
- Quantitative UPLC-MS/MS analysis of the gut microbial co-metabolites phenylacetylglutamine, 4-cresyl sulphate and hippurate in human urine: INTERMAP Study. (2012) (30)
- Intestinal ischemia/reperfusion injury: defining the role of the gut microbiome. (2009) (30)
- Quantitative structure-metabolism relationships for substituted benzoic acids in the rabbit: prediction of urinary excretion of glycine and glucuronide conjugates. (1996) (30)
- Dynamic biochemical information recovery in spontaneous human seminal fluid reactions via 1H NMR kinetic statistical total correlation spectroscopy. (2009) (29)
- NMR spectroscopic and theoretical chemistry studies on the internal acyl migration reactions of the 1-O-acyl-beta-D-glucopyranuronate conjugates of 2-, 3-, and 4-(trifluoromethyl) benzoic acids. (1996) (29)
- Metabolic Phenotypes of Carotid Atherosclerotic Plaques Relate to Stroke Risk: An Exploratory Study. (2016) (29)
- Relation of raw and cooked vegetable consumption to blood pressure: the INTERMAP Study (2012) (29)
- Integrative top-down system metabolic modeling in experimental disease states via data-driven Bayesian methods. (2008) (28)
- Identification of novel hydrazine metabolites by 15N-NMR. (1991) (28)
- Human sympathetic ophthalmia. Immunologic analysis of the vitreous and uvea. (1986) (28)
- Urinary metabolic phenotyping the slc26a6 (chloride-oxalate exchanger) null mouse model. (2012) (28)
- Chemical-exchange and paramagnetic T2 relaxation agents for water suppression in spin-echo proton nuclear magnetic resonance spectroscopy of biological fluids. (1987) (28)
- Chapter 1 – Metabonomics and Metabolomics Techniques and Their Applications in Mammalian Systems (2007) (28)
- Quantitative structure-toxicity relationships for halogenated substituted-benzenes to Vibrio fischeri, using atom-based semi-empirical molecular-orbital descriptors. (1999) (28)
- Characterization and quantification of metabolites of racemic ketoprofen excreted in urine following oral administration to man by 1H-NMR spectroscopy, directly coupled HPLC-MS and HPLC-NMR, and circular dichroism (2004) (28)
- Author Correction: Nutriome–metabolome relationships provide insights into dietary intake and metabolism (2020) (27)
- S-naproxen-beta-1-O-acyl glucuronide degradation kinetic studies by stopped-flow high-performance liquid chromatography-1H NMR and high-performance liquid chromatography-UV. (2001) (27)
- Global systems biology and personalized healthcare solutions. (2006) (27)
- A metabolic entropy approach for measurements of systemic metabolic disruptions in patho-physiological States. (2010) (27)
- Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health (2021) (27)
- Cephaloridine-induced nephrotoxicity in the Fischer 344 rat: proton NMR spectroscopic studies of urine and plasma in relation to conventional clinical chemical and histopathological assessments of nephronal damage (2005) (27)
- Proton NMR spectroscopy of bile for monitoring the excretion of endogenous and xenobiotic metabolites: application to para-aminophenol. (1989) (27)
- ¹H NMR-based metabonomics for investigating diabetes. (2009) (27)
- Metabolic phenotype modulation by caloric restriction in a lifelong dog study. (2013) (27)
- Statistical total correlation spectroscopy scaling for enhancement of metabolic information recovery in biological NMR spectra. (2012) (26)
- Proton NMR spectroscopic studies on the metabolism and biochemical effects of hydrazine in vivo (2005) (26)
- Optimized Phenotypic Biomarker Discovery and Confounder Elimination via Covariate-Adjusted Projection to Latent Structures from Metabolic Spectroscopy Data (2018) (26)
- 1H NMR spectroscopic and histopathological studies on propyleneimine-induced renal papillary necrosis in the rat and the multimammate desert mouse (Mastomys natalensis). (1997) (26)
- Use of an atmospheric solids analysis probe (ASAP) for high throughput screening of biological fluids: preliminary applications on urine and bile. (2010) (26)
- NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man. (1997) (26)
- Quantitation in gradient high performance liquid chromatography/inductively coupled mass spectrometry investigated using diclofenac and chlorpromazine. (2002) (26)
- Selective Inverse-Detected Long-Range HeteronuclearJ-Resolved NMR Spectroscopy and Its Application to the Measurement of3JCH (1995) (26)
- A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat urine. (2019) (25)
- A metabonomic analysis of insect development: 1H-NMR spectroscopic characterization of changes in the composition of the haemolymph of larvae and pupae of the tobacco hornworm, Manduca sexta (2008) (25)
- Application of directly coupled HPLC NMR to separation and characterization of lipoproteins from human serum. (2001) (25)
- Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier (2018) (25)
- Metabolism of 3-chloro-4-fluoroaniline in rat using [14C]-radiolabelling, 19F-NMR spectroscopy, HPLC-MS/MS, HPLC-ICPMS and HPLC-NMR (2006) (25)
- Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase. (2012) (25)
- Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: Measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS (2006) (25)
- BASIS: High-performance bioinformatics platform for processing of large-scale mass spectrometry imaging data in chemically augmented histology (2018) (25)
- A proton magnetic resonance study of the metabolism of N-methylformamide in the rat. (1986) (25)
- Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples (2020) (25)
- Use of directly coupled ion-exchange liquid chromatography-mass spectrometry and liquid chromatography-nuclear magnetic resonance spectroscopy as a strategy for polar metabolite identification. (2000) (25)
- Metabonomics in Diabetes Research (2007) (24)
- mQTL.NMR: an integrated suite for genetic mapping of quantitative variations of (1)H NMR-based metabolic profiles. (2015) (24)
- Statistical analysis in metabolic phenotyping (2021) (24)
- Studies on the relationship between acute testicular damage and urinary and plasma creatine concentration (2005) (24)
- Proton NMR monitoring of the onset and recovery of experimental renal damage. (1990) (24)
- High‐Resolution Magic Angle Spinning NMR Spectroscopy: Application to Biomedical Studies (2010) (24)
- Assignment of 1 H Nuclear Magnetic Resonance Visible Polyunsaturated Fatty Acids in BT 4 C Gliomas Undergoing Ganciclovir-Thymidine Kinase Gene Therapy-induced Programmed Cell Death 1 (2003) (24)
- Systems biology to battle vascular disease. (2010) (23)
- Proton magnetic resonance spectroscopy of human urine: Excretion of 1-(3'-carboxypropyl)-3,7-dimethylxanthine by man after dosing with oxpentifylline. (1987) (23)
- Effects of biliary cannulation and buthionine sulphoximine pretreatment on the nephrotoxicity of para-aminophenol in the Fischer 344 rat (2005) (23)
- Kidney lesions in juvenile starlings Sturnus vulgaris fed on a mercury-contaminated synthetic diet (1984) (23)
- 1H and 19F-nmr spectroscopic studies on the metabolism and urinary excretion of mono- and disubstituted phenols in the rat. (1996) (23)
- Comparative studies on the nephrotoxicity of 2-bromoethanamine hydrobromide in the Fischer 344 rat and the multimammate desert mouse (Mastomys natalensis) (2007) (23)
- Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension (2018) (23)
- Prediction of urinary sulphate and glucuronide conjugate excretion for substituted phenols in the rat using quantitative structure-metabolism relationships. (1995) (23)
- Application of the one-dimensional TOCSY pulse sequence in 750 MHz 1H-NMR spectroscopy for assignment of endogenous metabolite resonances in biofluids. (1994) (23)
- Human metabolic phenotyping and metabolome wide association studies. (2007) (23)
- Application of Capillary Electrophoresis–Mass Spectrometry to the Analysis of Urine Samples From Animals and Man Containing Paracetamol and Phenacetin and Their Metabolites (1997) (23)
- Association of Untargeted Urinary Metabolomics and Lung Cancer Risk Among Never-Smoking Women in China (2019) (23)
- Recent advances in high-resolution NMR spectroscopic methods in bioanalytical chemistry (1997) (23)
- Application of 1H NMR spectroscopy to the metabolic phenotyping of rodent brain extracts: A metabonomic study of gut microbial influence on host brain metabolism (2017) (23)
- Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1beta-O-acyl glucuronides. (2009) (23)
- Nutritional modulation of the metabonome: applications of metabolic phenotyping in translational nutritional research (2014) (22)
- Self-modeling curve resolution recovery of temporal metabolite signal modulation in NMR spectroscopic data sets: application to a life-long caloric restriction study in dogs. (2008) (22)
- Roux-en-Y gastric bypass-induced bacterial perturbation contributes to altered host-bacterial co-metabolic phenotype (2021) (22)
- The potential of 19F NMR spectroscopy for rapid screening of cell cultures for models of mammalian drug metabolism. (2001) (22)
- Integrated HPLC-MS and 1H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides (2010) (22)
- 1H NMR global metabolic phenotyping of acute pancreatitis in the emergency unit. (2014) (22)
- Longitudinal metabolic and gut bacterial profiling of pregnant women with previous bariatric surgery (2020) (22)
- LC-1H NMR used for determination of the elution order of S-naproxen glucuronide isomers in two isocratic reversed-phase LC-systems. (2001) (22)
- A rapid simple approach to screening pharmaceutical products using ultra-performance LC coupled to time-of-flight mass spectrometry and pattern recognition. (2008) (22)
- Dietary and Urinary Metabonomic Factors Possibly Accounting for Higher Blood Pressure of Black Compared With White Americans: Results of International Collaborative Study on Macro-/Micronutrients and Blood Pressure (2013) (22)
- The nPYc-Toolbox, a Python module for the pre-processing, quality-control and analysis of metabolic profiling datasets (2019) (22)
- NMR and QSAR studies on the transacylation reactivity of model 1β-O-acyl glucuronides. I: design, synthesis and degradation rate measurement (2004) (22)
- High-performance liquid chromatography-UV diode array, inductively coupled plasma mass spectrometry (ICMPS) and orthogonal acceleration time-of-flight mass spectrometry (oa-TOFMS) applied to the simultaneous detection and identification of metabolites of 4-bromoaniline in rat urine (2002) (22)
- Studies on the metabolism of 4-fluoroaniline and 4-fluoroacetanilide in rat: formation of 4-acetamidophenol (paracetamol) and its metabolites via defluorination and N-acetylation. (1999) (21)
- Dietary metabotype modelling predicts individual responses to dietary interventions (2020) (21)
- MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways (2016) (21)
- A pattern recognition approach to the comparison of PMR and clinical chemical data for classification of nephrotoxicity. (1990) (21)
- Weaning diet induces sustained metabolic phenotype shift in the pig and influences host response to Bifidobacterium lactis NCC2818 (2012) (21)
- Application of directly coupled high-performance liquid chromatography-nuclear magnetic resonance-mass spectrometry to the detection and characterisation of the metabolites of 2-bromo-4-trifluoromethylaniline in rat urine (1997) (20)
- A Unified Conceptual Framework for Metabolic Phenotyping in Diagnosis and Prognosis. (2019) (20)
- Urinary phenotyping indicates weight loss-independent metabolic effects of Roux-en-Y gastric bypass in mice. (2013) (20)
- Differences in Fecal Gut Microbiota, Short-Chain Fatty Acids and Bile Acids Link Colorectal Cancer Risk to Dietary Changes Associated with Urbanization Among Zimbabweans (2019) (20)
- Diffusion and Relaxation Edited Proton NMR Spectroscopy of Plasma Reveals a High-Fidelity Supramolecular Biomarker Signature of SARS-CoV-2 Infection (2021) (20)
- Metabolic profiling of CHO-AβPP695 cells revealed mitochondrial dysfunction prior to amyloid-β pathology and potential therapeutic effects of both PPARγ and PPARα Agonisms for Alzheimer's disease. (2015) (20)
- MWASTools: an R/bioconductor package for metabolome-wide association studies (2017) (20)
- Seminal oligouridinosis: low uridine secretion as a biomarker for infertility in spinal neurotrauma. (2008) (19)
- Enhanced effect of magnetic field gradients using multiple quantum NMR spectroscopy applied to self-diffusion coefficient measurement (1998) (19)
- NMR spectroscopic studies of the transacylation reactivity of ibuprofen 1-beta-O-acyl glucuronide. (2006) (19)
- 88MHz 113Cd-n.m.r. studies of native rat liver metallothioneins. (1983) (19)
- Broad-ranging natural metabotype variation drives physiological plasticity in healthy control inbred rat strains. (2011) (19)
- Integrative Modeling of Plasma Metabolic and Lipoprotein Biomarkers of SARS-CoV-2 Infection in Spanish and Australian COVID-19 Patient Cohorts. (2021) (19)
- Comparative biochemical effects of low doses of mercury II chloride in the F344 rat and the multimammate mouse (Mastomys natalensis). (1996) (19)
- Identification of the urinary metabolites of 4-bromoaniline and 4-bromo- [carbonyl - 13 C]-acetanilide in rat (2002) (19)
- Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat. (1999) (19)
- High-performance liquid chromatography directly coupled to 19F and 1H NMR for the analysis of mixtures of isomeric ester glucuronide conjugates of trifluoromethylbenzoic acids (1996) (19)
- Proton NMR analysis of plasma from renal failure patients: evaluation of sample preparation and spectral-editing methods. (1990) (19)
- The fine structure of dark or intercalated cells from the distal and collecting tubules of avian kidneys. (1983) (18)
- Modeling the effects of toxins in metabolic networks. (2007) (18)
- Metabolic Phenotype of Obesity in a Saudi Population. (2017) (18)
- The development and application of coupled HPLC-NMR spectroscopy. (1996) (18)
- In-vitro identification of distinctive metabolic signatures of intact varicose vein tissue via magic angle spinning nuclear magnetic resonance spectroscopy. (2012) (17)
- Recovery of underwater resonances by magnetization transferred NMR spectroscopy (RECUR-NMR). (2001) (17)
- Application of inductively coupled plasma mass spectrometry and high-performance liquid chromatography--with parallel electrospray mass spectrometry to the investigation of the disposition and metabolic fate of 2-, 3- and 4-iodobenzoic acids in the rat. (2004) (17)
- Development of a simple liquid chromatographic method for the separation of mixtures of positional isomers and anomers of synthetic 2-, 3- and 4-fluorobenzoic acid glucuronides formed via acyl migration reactions. (1996) (17)
- Determination of the relative NH proton lifetimes of the peptide analogue viomycin in aqueous solution by NMR-based diffusion measurement (1999) (17)
- 750 MHz HPLC-NMR spectroscopic identification of rat microsomal metabolites of phenoxypyridines. (1997) (17)
- Diagnostic Potential of the Plasma Lipidome in Infectious Disease: Application to Acute SARS-CoV-2 Infection (2021) (17)
- Urinary metabolic phenotyping for Alzheimer’s disease (2020) (17)
- Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol (2019) (17)
- Investigation of the metabolism of 14C/13C-practolol in rat using directly coupled radio-HPLC-NMR-MS (2000) (17)
- Selective Detection of 1H NMR Resonances of CHn Groups Using a Heteronuclear Maximum-Quantum Filter and Pulsed Field Gradients (1995) (17)
- Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series (2016) (16)
- NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat. (1997) (16)
- Statistical HOmogeneous Cluster SpectroscopY (SHOCSY): An Optimized Statistical Approach for Clustering of 1H NMR Spectral Data to Reduce Interference and Enhance Robust Biomarkers Selection (2014) (16)
- Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1‐cyano‐2‐hydroxy‐3‐butene in the rat (2009) (16)
- Kinetic studies on the intramolecular acyl migration of β-1-O-acyl glucuronides: Application to the glucuronides of (R)- and (S)-ketoprofen, (R)- and (S)-hydroxy-ketoprofen metabolites, and tolmetin by 1H-NMR spectroscopy (2005) (16)
- Systemic Characterization of an Obese Phenotype in the Zucker Rat Model Defining Metabolic Axes of Energy Metabolism and Host-Microbial Interactions. (2016) (15)
- Analysis of biological fluids by high-field nuclear magnetic resonance spectroscopy (1989) (15)
- Non-linear modeling of 1H NMR metabonomic data using kernel-based orthogonal projections to latent structures optimized by simulated annealing. (2011) (15)
- J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis. (2017) (15)
- SPUTNIK: an R package for filtering of spatially related peaks in mass spectrometry imaging data (2018) (15)
- The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR. (2002) (15)
- First example of hepatocyte transplantation to alleviate ornithine transcarbamylase deficiency, monitored by NMR-based metabonomics. (2009) (15)
- Investigation of the quantitative metabolic fate and urinary excretion of 3-methyl-4-trifluoromethylaniline and 3-methyl-4-trifluoromethylacetanilide in the rat. (1999) (15)
- Application of directly coupled high performance liquid chromatography-NMR-mass spectometry and 1H NMR spectroscopic studies to the investigation of 2,3-benzofuran metabolism in Sprague-Dawley rats. (2002) (15)
- Topics in Xenobiochemistry: Do metabolic pathways exist for xenobiotics? The micro-metabolism hypothesis (2003) (15)
- Determination of platinum in urine, ultrafiltrate, and whole plasma by isotope dilution gas chromatography-mass spectrometry compared to electrothermal atomic absorption spectrometry. (1993) (15)
- Studies on the metabolism of fluorinated xenobiotics in the rat using 19F-NMR and 1H-NMR spectroscopy. (1990) (15)
- Reviewers peering from under a pile of ‘omics’ data (2006) (15)
- NMR studies of crab and plaice metallothioneins. (1986) (15)
- Bacterial adaptation to the gut environment favors successful colonization (2011) (15)
- High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma. (2010) (15)
- Addressing the challenge of limited sample volumes in in vitro studies with capillary-scale microfluidic LC-MS/MS. (2011) (14)
- Hepatotoxin-induced hypertyrosinemia and its toxicological significance (2007) (14)
- Ultra-Performance Liquid Chromatography–High-Resolution Mass Spectrometry and Direct Infusion–High-Resolution Mass Spectrometry for Combined Exploratory and Targeted Metabolic Profiling of Human Urine (2018) (14)
- Asymptomatic 5-oxoprolinuria detected by proton magnetic resonance spectroscopy. (1993) (14)
- Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery (2017) (14)
- Chemical shift calibration of 1H MAS NMR liver tissue spectra exemplified using a study of glycine protection of galactosamine toxicity (2009) (14)
- X-ray microanalysis of proximal and distal tubule cells in the mouse kidney, and the influence of cadmium on the concentration of natural intracellular elements. (1983) (13)
- Investigation of the metabolic fate of 2-, 3- and 4-bromobenzoic acids in bile-duct-cannulated rats by inductively coupled plasma mass spectrometry and high-performance liquid chromatography/inductively coupled plasma mass spectrometry/electrospray mass spectrometry. (2005) (13)
- High-field deuterium nuclear magnetic resonance spectroscopic monitoring of the pharmacokinetics of selectively deuterated benzoic acid in man. (1994) (13)
- Identification and quantification of metabolites of 2,3,5,6-tetrafluoro-4-trifluoromethylaniline in rat urine using 19F nuclear magnetic resonance spectroscopy, high-performance liquid chromatography-nuclear magnetic resonance spectroscopy and high-performance liquid chromatography-mass spectrometry (2000) (13)
- Roux-en-Y gastric bypass surgery in Zucker rats induces bacterial and systemic metabolic changes independent of caloric restriction-induced weight loss (2021) (13)
- COMET and the challenge of drug safety screening. (2007) (13)
- A novel LC-MS approach for the detection of metabolites in DMPK studies. (2010) (13)
- Nuclear Magnetic Resonance Spectroscopy: A Non-Invasive Probe of Kidney Metabolism and Function (1998) (13)
- Integrated Histopathological and Urinary Metabonomic Investigation of the Pathogenesis of Microcystin-LR Toxicosis (2013) (13)
- High-performance liquid chromatography/inductively coupled plasma mass spectrometry with iodine-specific detection for profiling the metabolites produced in the earthworm Eisenia veneta by exposure to 2-fluoro-4-iodoaniline. (2003) (13)
- 1H-NMR spectroscopy of biofluids and the investigation of xenobiotic-induced changes in liver biochemistry. (1990) (13)
- Synthesis of a series of phenylacetic acid 1-β-O-acyl glucosides and comparison of their acyl migration and hydrolysis kinetics with the corresponding acyl glucuronides. (2011) (13)
- Selective Detection of 1H NMR Resonances of 13CHn Groups Using Two-Dimensional Maximum-Quantum Correlation Spectroscopy (1995) (13)
- Urinary Metabolic Phenotyping of Women with Lower Urinary Tract Symptoms. (2017) (12)
- Determination of tellurium in urine by isotope dilution gas chromatography/mass spectrometry using (4-fluorophenyl)magnesium bromide as a derivatizing agent and a comparison with electrothermal atomic absorption spectrometry. (1994) (12)
- A multiplexed targeted assay for high-throughput quantitative analysis of serum methylamines by ultra performance liquid chromatography coupled to high resolution mass spectrometry. (2016) (12)
- NMR spectroscopic diffusion, chemical shift and linewidth measurements of low‐affinity binding of ibuprofen enantiomers to human serum albumin (1999) (12)
- Deuterium NMR spectroscopy of biofluids for the identification of drug metabolites: application to N,N-dimethylformamide. (1993) (12)
- Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes. (2010) (12)
- Two‐dimensional 1H1H and 13C1H maximum‐quantum correlation NMR spectroscopy with application to the assignment of the NMR spectra of the bile salt sodium taurocholate (1995) (12)
- Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanilic acid formation using computational chemistry (2002) (12)
- An NMR-based metabolomic approach to the analysis of the effects of xenobiotics on endogenous metabolite levels in plants (2004) (12)
- Studies on the comparative toxicity of S-(1,2-dichlorovinyl)-L-cysteine, S-(1,2-dichlorovinyl)-L-homocysteine and 1,1,2-trichloro-3,3,3-trifluoro-1-propene in the Fischer 344 rat (2009) (12)
- Comparative distributions of zinc, cadmium and mercury in the tissues of experimental mice. (1984) (12)
- A 1H NMR spectroscopic study of the biochemical effects of ifosfamide in the rat: evaluation of potential biomarkers (2000) (12)
- 1 H NMR and UPLC-MS E statistical heterospectroscopy: Characterization of drug metabolites (Xenometabolome) in epidemiological studies (Analytical Chemistry (2008) 80, (6835-6844)) (2008) (12)
- Degradation of 4-fluorobiphenyl in soil investigated by 19F NMR spectroscopy and 14C radiolabelling analysis. (1999) (12)
- Proton nuclear magnetic resonance of urine and bile from paracetamol dosed rats. (1990) (12)
- A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS. (2021) (12)
- 1H NMR spectroscopic studies on the reactions of haloalkylamines with bicarbonate ions: formation of N-carbamates and 2-oxazolidones in cell culture media and blood plasma. (1995) (12)
- Investigation of the feasibility of directly-coupled HPLC-NMR with 2H detection with application to the metabolism of N-dimethylformamide-d7. (1997) (11)
- Proton NMR studies on the effects of uranyl nitrate on the biochemical composition of rat urine and plasma. (1990) (11)
- An integrated ceramic, micro-fluidic device for the LC/MS/MS analysis of pharmaceuticals in plasma. (2015) (11)
- The metabolism of 2-trifluormethylaniline and its acetanilide in the rat by 19F NMR monitored enzyme hydrolysis and 1H/19F HPLC-NMR spectroscopy. (2003) (11)
- Characterisation of putative pentose-containing conjugates as minor metabolites of 4-bromoaniline present in the urine of rats following intraperitoneal administration. (2003) (11)
- Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women (2018) (11)
- Quantitative structure-toxicity relationships for halobenzenes in two species of bioluminescent bacteria, Pseudomonas fluorescens and Vibrio fischeri, using an atom-centered semi-empirical molecular-orbital based model (1999) (11)
- Systematic Isolation and Structure Elucidation of Urinary Metabolites Optimized for the Analytical-Scale Molecular Profiling Laboratory (2019) (11)
- Diffusion Coefficient Measurement by High Resolution NMR Spectroscopy: Biochemical and Pharmaceutical Applications (1999) (11)
- Metabolic phenotyping for discovery of urinary biomarkers of diet, xenobiotics and blood pressure in the INTERMAP Study: an overview (2017) (11)
- 19 F-NMR and directly coupled 19 F/ 1 H-HPLC-NMR spectroscopic investigations of the metabolism of the model ecotoxin 3-trifluoromethylaniline in the earthworm species Eisenia veneta (2002) (10)
- NMR-monitored solid-phase extraction of phenolphthalein glucuronide on phenylboronic acid and C18 bonded phases. (1991) (10)
- Development of a Pipeline for Exploratory Metabolic Profiling of Infant Urine. (2016) (10)
- Cadmium complexes of dicysteinoethylenediaminetetraacetic acid exhibit cadmium-113 NMR shifts and cadmium-113-cadmium-113 couplings similar to those of metallothionein (1984) (10)
- Modeling Longitudinal Metabonomics and Microbiota Interactions in C57BL/6 Mice Fed a High Fat Diet. (2016) (10)
- Early immune pathology and persistent dysregulation characterise severe COVID-19 (2020) (10)
- Assignment of the 750 MHz 1H NMR resonances from a mixture of transacylated ester glucuronic acid conjugates with the aid of oversampling and digital filtering during acquisition. (1995) (10)
- Early intervention with Bifidobacterium lactis NCC2818 modulates the host-microbe interface independent of the sustained changes induced by the neonatal environment (2017) (10)
- A validated UPLC-MS/MS assay for the quantification of amino acids and biogenic amines in rat urine. (2019) (10)
- Characterization of metabolites in intact Streptomyces citricolor culture supernatants using high-resolution nuclear magnetic resonance and directly coupled high-pressure liquid chromatography-nuclear magnetic resonance spectroscopy. (1999) (10)
- Metabolism of 2-fluoro-4-iodoaniline in earthworm Eisenia veneta using 19F-NMR spectroscopy, HPLC-MS, and HPLC-ICPMS (127I) (2007) (10)
- pJRES Binning Algorithm (JBA): a new method to facilitate the recovery of metabolic information from pJRES 1H NMR spectra (2018) (10)
- Low Volume in Vitro Diagnostic Proton NMR Spectroscopy of Human Blood Plasma for Lipoprotein and Metabolite Analysis: Application to SARS-CoV-2 Biomarkers (2021) (10)
- Improvement in the characterization of minor drug metabolites from HPLC-NMR studies through the use of quantified maximum entropy processing of NMR spectra. (1994) (10)
- Cellular acidosis in rodents exposed to cadmium is caused by adaptation of the tissue rather than an early effect of toxicity. (2007) (9)
- 2.7.5. HPLC/NMR and related hyphenated NMR methods (2000) (9)
- Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment (2019) (9)
- Application of the FLIPSY pulse sequence for increased sensitivity in 1H NMR-based metabolic profiling studies. (2008) (9)
- Systems toxicology: modelling biomarkers of glutathione homeostasis and paracetamol metabolism. (2015) (9)
- Urinary metabolites of 2-bromoethanamine identified by stable isotope labelling: evidence for carbamoylation and glutathione conjugation (2011) (9)
- Probing molecular dynamics in chromatographic systems using high-resolution 1H magic-angle-spinning NMR spectroscopy: interaction between p-Xylene and C18-bonded silica. (2004) (9)
- Studies on the biochemical effects of the aldose reductase inhibitor 2,7-difluorospirofluorene-9,5'-imidazolidine-2',4'-dione (Al 1576, HOE 843). Detection of D-glucaric and D-glucuronic acid excretion by high resolution 1H and 13C NMR spectroscopy. (1992) (9)
- The pathophysiology of human obstructive cholestasis is mimicked in cholestatic Gold Syrian hamsters. (2018) (9)
- Quantitative urinalysis of the mercapturic acid conjugates of allyl formate using high-resolution NMR spectroscopy. (2006) (8)
- A Nuclear Magnetic Resonance Approach to Investigate the Biochemical and Molecular Effects of Nephrotoxins (1987) (8)
- The Modulation of Drug Efficacy and Toxicity by the Gut Microbiome (2015) (8)
- Biofluids Studied By NMR (1999) (8)
- -Omics dreams of personalized healthcare. (2006) (8)
- Rapid multi-component detection of fluorinated drug metabolites in whole urine from a ‘cassette’ dose study using high resolution 19F NMR spectroscopy (1999) (8)
- Isotopic enrichment enhancement in metabonomic analysis of UPLC-MS data sets (2007) (8)
- Automatic Spectroscopic Data Categorization by Clustering Analysis (ASCLAN): A Data-Driven Approach for Distinguishing Discriminatory Metabolites for Phenotypic Subclasses. (2016) (8)
- Abstract 3977: iKnife: Rapid evaporative ionization mass spectrometry (REIMS) enables real-time chemical analysis of the mucosal lipidome for diagnostic and prognostic use in colorectal cancer (2016) (8)
- A study of the metabolism of dimethylformamide in the rat by high resolution proton NMR spectroscopy. (1989) (8)
- Translational utility of a hierarchical classification strategy in biomolecular data analytics (2017) (8)
- 19F NMR Studies of the Metabolism of Trifluoromethylaniline (1988) (7)
- Impact of the gut microbiota on inflammation, obesity, and metabolic disease (2016) (7)
- Observation of Separate J-Resolved 1H-NMR Spectra from CH, CH2, and CH3 Groups Using a Maximum-Quantum Filter (1995) (7)
- Application of 1 H- and 19 F-NMR spectroscopy in the investigation of the urinary and biliary excretion of 3,5-, 2,4-ditrifluoromethylbenzoic and pentafluorobenzoic acids in rat (2002) (7)
- 19F NMR spectroscopic investigation into the absorption and metabolism of 3-trifluoromethylaniline in Eisenia veneta. (2003) (7)
- Integrated fecal microbiome–metabolome signatures reflect stress and serotonin metabolism in irritable bowel syndrome (2022) (7)
- Development of nanoelectrospray high resolution isotope dilution mass spectrometry for targeted quantitative analysis of urinary metabolites: application to population profiling and clinical studies† (2015) (7)
- Encyclopedia of Spectroscopy and Spectrometry, 2nd Edition (2010) (7)
- Quantitative structure―chromatography relationships : prediction of TLC behavior using theoretically derived molecular properties (1991) (7)
- Raised transaminase activity of blood plasma from rats with experimentally-induced kidney damage detected by spin-echo 1H-NMR spectroscopy. (1993) (6)
- Use of high-field nuclear magnetic resonance spectroscopy for the analysis of biological fluids (1991) (6)
- Biomedical and Pharmaceutical Applications of HPLC–NMR and HPLC–NMR–MS (2003) (6)
- Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota (2018) (6)
- (1)H NMR spectroscopic studies on the characterization of renal cell lines and identification of novel potential markers of in vitro nephrotoxicity. (1996) (6)
- Quantitative Investigation of Probabilistic Spectral Processing Methods Using Simulated NMR Data (2001) (6)
- Surgical systems biology and personalized longitudinal phenotyping in critical care. (2012) (6)
- Metabolic Phenotyping Using UPLC–MS and Rapid Microbore UPLC–IM–MS: Determination of the Effect of Different Dietary Regimes on the Urinary Metabolome of the Rat (2020) (5)
- Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women (2018) (5)
- Development and validation of a high performance liquid chromatography-tandem mass spectrometry method for the absolute analysis of 17 α D-amino acids in cooked meals. (2020) (5)
- APPLICATION OF HIGH RESOLUTION H-NMR SPECTROSCOPY TO THE DETECTION OF PENICILLAMINE AND ITS METABOLITES IN HUMAN URINE (1988) (5)
- Molecular Phenomic Approaches to Deconvolving the Systemic Effects of SARS-CoV-2 Infection and Post-acute COVID-19 Syndrome (2021) (5)
- Network Mapping of Molecular Biomarkers Influencing Radiation Response in Rectal Cancer. (2019) (5)
- J-Edited DIffusional Proton Nuclear Magnetic Resonance Spectroscopic Measurement of Glycoprotein and Supramolecular Phospholipid Biomarkers of Inflammation in Human Serum. (2022) (5)
- Detection of mono- and di-hexoses as metabolites of 4-bromoaniline using HPLC-TOF-MS/MS (2003) (5)
- Liquid chromatography directly and jointly combined with nuclear magnetic resonance spectroscopy and mass spectrometry (1998) (5)
- Metabonomics and Metabolomics (2006) (5)
- Exploration of Human Serum Lipoprotein Supramolecular Phospholipids Using Statistical Heterospectroscopy in n-Dimensions (SHY-n): Identification of Potential Cardiovascular Risk Biomarkers Related to SARS-CoV-2 Infection. (2022) (4)
- Direct low field J-edited diffusional proton NMR spectroscopic measurement of COVID-19 inflammatory biomarkers in human serum. (2022) (4)
- Studies on the effects of L(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) on 4-aminophenol-induced nephrotoxicity in the Fischer 344 rat. (1993) (4)
- Improved Spatial Resolution of Metabolites in Tissue Biopsies Using High-Resolution Magic-Angle-Spinning Slice Localization NMR Spectroscopy. (2020) (4)
- Comparison of Maximum Quantum Filtered NMR Spectroscopy (MAXY NMR) and Other Two‐Dimensional NMR Approaches for Resonance Assignment of Peptides (1996) (4)
- Investigation of basic mobile phases with positive ESI LC-MS for metabonomics studies. (2012) (4)
- Microbiome Inhibition of IRAK-4 by Trimethylamine Mediates Metabolic and Immune Benefits in High-Fat-Diet-induced Insulin Resistance (2018) (4)
- Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-N-oxide. (2022) (4)
- Diagnosis of borderline ovarian tumours by rapid evaporative ionisation mass spectrometry (REIMS) using the surgical intelligent knife (iKnife) (2016) (4)
- Studies on the effects ofl(αS,5S)-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) on 4-aminophenol-induced nephrotoxicity in the Fischer 344 rat (2005) (4)
- Quantitative structure-toxicity relationships for chlorophenols to bioluminescent lux-marked bacteria using atom-based semi-empirical molecular-orbital descriptors. (1999) (4)
- Strategic applications of proton nuclear magnetic resonance spectroscopy in clinical biochemistry and analytical toxicology (1991) (4)
- The Role of Nuclear Magnetic Resonance Spectroscopy in Drug Metabolism (1999) (4)
- Spatially resolved profiling of colorectal cancer lipid biochemistry via DESI imaging mass spectrometry to reveal morphology-dependent alterations in fatty acid metabolism. (2016) (4)
- d 3 D-DESI imaging reveal the hidden metabolic heterogeneity of cancer † (2017) (4)
- Probing the reactivity of the zinc and cadmium ions bound to rabbit liver metallothioneins with EDTA. (1987) (3)
- Pharmacometabonomics and Predictive Metabonomics: New Tools for Personalized Medicine (2016) (3)
- The histology and fine structure of the ureter of the European starling (Sturnus vulgaris). (1983) (3)
- Multivariate Data Analysis Methods for NMR‐based Metabolic Phenotyping in Pharmaceutical and Clinical Research (2015) (3)
- Physiological Variation in Laboratory Animals and Humans (2005) (3)
- The metabolic fate and effects of 2-Bromophenol in male Sprague–Dawley rats (2019) (3)
- Peer Reviewed: Advancing Hyphenated Chromatographic Systems. (2000) (3)
- Network analysis of mass spectrometry imaging data from colorectal cancer identifies key metabolites common to metastatic development (2017) (3)
- Standardisation of Reporting Methods for Metabolic Analyses : A Draft Policy Document from the Standard Metabolic Reporting Structures (2005) (3)
- Correction to 2-Furoylglycine as a Candidate Biomarker of Coffee Consumption. (2016) (3)
- A targeted ultra performance liquid chromatography - Tandem mass spectrometric assay for tyrosine and metabolites in urine and plasma: Application to the effects of antibiotics on mice. (2020) (3)
- An NMR study of the metabolic fate of 2-, 3- and 4-fluorobenzyl alcohols in the rat: detection of N-acetylcysteinyl conjugates as minor metabolites in urine. (2003) (3)
- Response to Comment on “Optimized Preprocessing of Ultra-Performance Liquid Chromatography/Mass Spectrometry Urinary Metabolic Profiles for Improved Information Recovery” (2011) (3)
- A patient-centric modeling framework captures recovery from SARS-CoV-2 infection (2023) (3)
- High Resolution 1H NMR Spectroscopic Monitoring of Extraction of Model Glucuronides on Phenylboronic Acid and C18 Bonded Phases (1994) (3)
- Investigation of water environments in a C18 bonded silica phase using 1H magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy. (2001) (3)
- UPLC-MS, HPLC-radiometric, and NMR-spectroscopic studies on the metabolic fate of 3-fluoro-[U-14C]-aniline in the bile-cannulated rat (2010) (3)
- Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome (2021) (3)
- Obesity and Cage Environment Modulate Metabolism in the Zucker Rat: A Multiple Biological Matrix Approach to Characterizing Metabolic Phenomena. (2019) (3)
- Modernizing dietary assessment (2017) (2)
- Proton NMR Studies on the Metabolism and Biochemical Effects of Hydrazine In Vivo (1988) (2)
- Dietary fibre to reduce colon cancer risk in Alaska Native people: the Alaska FIRST randomised clinical trial protocol (2021) (2)
- Microbial–host metabolic systems interactions and the gut–brain axis: protective effects of microbial propionate upon the blood–brain barrier (2017) (2)
- Characterisation of the vaginal microbiome in cervical intraepithelial neoplasia (2016) (2)
- Enhancing the accuracy of surgical wound excision following burns trauma via application of Rapid Evaporative IonisationMass Spectrometry (REIMS). (2022) (2)
- Neuroendocrine Neoplasms: Identification of Novel Metabolic Circuits of Potential Diagnostic Utility (2021) (2)
- Conception, Implementation and Operation of Large-Scale Metabolic Phenotyping Centres: Phenome Centres (2019) (2)
- The Microbial Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function (2018) (2)
- Comprehensive Lipidomic Workflow for Multicohort Population Phenotyping Using Stable Isotope Dilution Targeted Liquid Chromatography-Mass Spectrometry. (2023) (2)
- Chapter 10 Biomedical applications of directly–coupled chromatography—nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) (2003) (2)
- High Resolution Nuclear Magnetic Resonance Spectroscopy in Clinical Chemistry and Disease Diagnosis (1989) (2)
- Liquid chromatography coupled with high-field proton nuclear magnetic resonance spectroscopy : current status and future prospects (1993) (2)
- Modeling People and Populations: Exploring Medical Visualization Through Immersive Interactive Virtual Environments (2016) (2)
- An Overview of Metabonomics (2005) (2)
- Microbiome Determinants and Physiological Effects of the Benzoate-Hippurate Microbial-Host Co-Metabolic Pathway (2019) (2)
- Su2092 A High Fat Lower Fiber Dietary Intervention Perturbs the Urinary Metabonome and Gut Microbial Co-Metabolic Processes in a Population of African and African Americans (2014) (2)
- Metabolism of [14C]-5-chloro-1,3-benzodioxol-4-amine in male Wistar-derived rats following intraperitoneal administration (2007) (2)
- The metabolism and excretion of [14c] 2- and 4-chlorobenzoic acids in the rat. (2000) (2)
- 2012 Scientific Session of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) San Diego, California, USA, 7–10 March 2012 Poster Presentations (2012) (2)
- Comparison of N-methylformamide-induced hepatotoxicity and metabolism in rats and mice. (1986) (2)
- Proton Nmr Spectroscopy of Bile as a Marker of Liver Function in Liver Transplant Patients (1990) (2)
- Erratum: Ethyl glucoside in human urine following dietry exposure: Detection by 1H NMR spectroscopy as a result of metabonomic screening of humans (Analyst (2004) 129 (259) DOI: 10.1039/b314316n) (2004) (2)
- Overview of the Nomenclature and Network of Contributors to the Development of Bioreactors for Human Gut Simulation Using Bibliometric Tools: A Fragmented Landscape (2022) (2)
- Multivariate metabotyping of plasma accurately predicts survival in patients with decompensated cirrhosis * (2017) (2)
- Metabonomics: NMR Techniques (2008) (1)
- Chapter 19 – Global Systems Biology Through Integration of “Omics” Results (2007) (1)
- Characterizing the metabolic effects of the selective inhibition of gut microbial β-glucuronidases in mice (2022) (1)
- Unmet medical needs (2019) (1)
- Application of 1H NMR Urinalysis to the Examination of Nephrotoxic Lesions Induced by Mercuric Chloride, Hexachloro-1, 3-Butadiene, and Propyleneimine (1989) (1)
- Novel drug metabolism and excretion studies using high resolution proton nmr spectroscopy (1985) (1)
- Metabolomics in the Cloud: Scaling Computational Tools to Big Data (2019) (1)
- Abstract 4974: Prospective study of untargeted urinary metabolomics and risk of lung cancer among female never-smokers in Shanghai, China (2018) (1)
- Kisspeptin stimulates insulin secretion and modulates serum metabolites in humans (2018) (1)
- Effects of gut-derived trimethylamines on the blood–brain barrier (2018) (1)
- Revised method of proton NMR urinalysis for detecting inborn errors of metabolism: a critique. (1988) (1)
- Phenotyping the Patient Journey (2016) (1)
- The Metabolic Window into Systems Biology (2007) (1)
- Metabolic Phenotyping: History, Status, and Prospects (2019) (1)
- Chapter 12:Metabonomics and Global Systems Biology (2007) (1)
- Future Visions for Clinical Metabolic Phenotyping: Prospects and Challenges (2016) (1)
- 1869: Nuclear Magnetic Resonance Based Metabonomic Investigation of Semen, Urine and Plasma Metabolite Profiles in Healthy Volunteers and Men with Spinal Cord Injury (2007) (1)
- Mo1905 Microbiome-Metabonome Linked Analysis of Ascending Colon Cancer by 1HNMR MAS Spectrometry and 16S rRNA Gene Analysis (Metataxonomics) (2014) (1)
- Use of cyclodextrins and their derivatives for chiral analysis by high field nuclear magnetic resonance spectroscopy (1992) (1)
- Deep learning and 3D-DESI imaging reveal the hidden metabolic heterogeneity of cancer † Society of Chemistry (2017) (1)
- Tu1477 Near Real Time Characterisation of Colorectal Cancer and Adenomatous Polyps Using Rapid Evaporative Ionisation Mass Spectrometry (Reims) (2014) (1)
- 24 - A novel route to controlling Clostridioides Difficile growth via short chain fatty acid and bile acid modulation (2018) (1)
- The Application of High Resolution Proton NMR Spectroscopy to the Detection of Drug Metabolites in Biological Samples (1986) (1)
- Chapter 5 Chromatographic and Electrophoretic Separations Combined with Mass Spectrometry for Metabonomics (2011) (1)
- 19 Metabonomic approaches to the understanding of direct and idiosyncratic drug toxicity (2003) (1)
- Comparative nephrotoxicity of cadmium and mercury in experimental animals in relation to tissue metal pharmacodynamics (1981) (1)
- Towards elucidating a universal panel of diagnostic biomarkers for early hepatocellular carcinoma (2018) (1)
- Cadmium and mercury in seabirds. (1984) (1)
- Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations (2012) (1)
- NMR-based Metabonomics Techniques and Applications (2008) (1)
- Differential susceptibility to n methylformamide induced hepatotoxicity in rats and mice (1985) (1)
- High glucose and low lactate: a metabolic signature of hypertension in human serum? (2008) (1)
- METABONOMICS a generic platform for the investigation of drug toxicity , altered gene function and disease processes (1)
- Abstract P179: Relation of Diet-Induced Metabolic Acidosis to Blood Pressure (2014) (1)
- Novel data processing and image co-registration algorithm for region-specific lipid profiling in colorectal cancer tissue using DESI imaging mass spectrometry. (2013) (1)
- Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy (Analytical Chemistry (2007) 79 (2629-2640)) (2008) (1)
- Systemic long-term metabolic effects of acute non-severe paediatric burn injury (2022) (1)
- Abstract P280: Urinary Hippurate and Proline Betaine Excretion relative to Fleshy Fruit Intake and Blood Pressure: The INTERMAP Study (2014) (0)
- Nutriome–metabolome relationships provide insights into dietary intake and metabolism (2020) (0)
- Hexanoylglycin as a biomarker for the predisposition of weight gain and obesity (2013) (0)
- K-1Systems medicine, microbiomes and personalised healthcare (2015) (0)
- The iKnife: Analysis of diathermy plumes by high-resolution mass spectrometry provides real-time identification of colorectal cancer liver metastases (2012) (0)
- Retraction Note: Dietary metabotype modelling predicts individual responses to dietary interventions (2023) (0)
- Cadmium Complexes of Dicysteinoethylenediaminetetraacetic Acid Exhibit113Cd NMR Shifts and113Cd-113Cd Couplings Similar to Those of Metallothionein. (1984) (0)
- URINARY METABOLIC PHENOTYPE OF BLOOD PRESSURE (2021) (0)
- Application of high resolution 1H-NMR spectroscopy to the detection of penicillamine and its metabolites in human urine. (1988) (0)
- Highresolution 1Hn.m.r. studies ofvertebrate blood andplasma (1983) (0)
- 722 COMPREHENSIVE METABOLIC PROFILING IN RISK STRATIFICATION OF HUMAN CAROTID ATHEROSCLEROSIS (2011) (0)
- Propionate has protective and anti-inflammatory effects on the blood–brain barrier (2018) (0)
- Differential Impacts of Dietary Modification on Individual Metabolic Phenotypes and their Relationship to Blood Pressure: Evidence of Latent Dietary Responder Sub-phenotypes (2017) (0)
- Cephaloridine-induced nephrotoxicity in the fischer 344 rat proton NMR spectroscopic studies of urine and plasma in relation to conventional clinical chemical and histopathological assessments of nephronal damage (1993) (0)
- OP-EHEA190237_online 2883..2898 (2019) (0)
- Abstract 839: Network-driven analytics of published tissue-based biomarkers to predict response to neoadjuvant therapy in rectal cancer (2017) (0)
- The identification of a marker of phospholipidosis using biofluid 1H NMR spectroscopy (2000) (0)
- The Development of a Metabonomic‐Based Drug Safety Testing Paradigm (2008) (0)
- Abstract 5269: Discovery and validation of plasma acylcarnitines for the early diagnosis of hepatocellular carcinoma (2019) (0)
- Biology 2401 Human Anatomy & Physiology (2009) (0)
- Sa022 A HIGH-FIBER LOW-FAT DIET INCREASES FECAL LEVELS OF LITHOCHOLIC ACID DERIVATIVE 3-KETOCHOLANIC ACID (2021) (0)
- Isovalerylglycin as a biomarker for predisposition to weight gain and obesity (2013) (0)
- A method for the quality control and standardization of medicinal plant products (2000) (0)
- Metabolism and Metabolites: Putting Proteomes into Perspective (2005) (0)
- Evaluation of high resolution magic-angle coil spinning NMR ( HR-MACS-NMR ) spectroscopy for metabolic profiling of nanoliter tissue biopsies (2015) (0)
- We-P11:201 Metabonomic characterization of nutritional and environmental signatures in human population studies (2006) (0)
- NMR spectroscopy and pattern recognition methods. Novel findings associated with alterations in nicotinic acid metabolism within autistic individuals showing increased urinary excretion of N-methyl-2-pyridone-5- carboxamide, N-methyl nicotinic acid and N-methyl nicotinamide, indicate a perturbation (2015) (0)
- FINAL ID: 24 TITLE: A NOVEL ROUTE TO CONTROLLING CLOSTRIDIOIDES DIFFICILE GROWTH VIA SHORT CHAIN FATTY ACID AND BILE ACID MODULATION (2018) (0)
- PP122 WEANING DIET IMPACTS THE ACTION OF BIFIDOBACTERIUM LACTIS IN THE PIG AND INITIATES A SUSTAINABLE METABOLIC REPROGRAMMING EVENT (2010) (0)
- More spin: Magic angle spinning proton NMR studies of biopsy size pancreatic samples (2004) (0)
- Prospective Study of Untargeted Urinary Metabolomics and Risk of Lung Cancer among Never-Smoking Women in Shanghai, China (2018) (0)
- Identifying unknown metabolites using NMR-based metabolic profiling techniques (2020) (0)
- Proton Nuclear Magnetic Spectroscopy: A Novel Method for the Study of Solid Phase Extraction (1994) (0)
- Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series (2016) (0)
- A network-based data-mining approach to investigate indole-related microbiota-host co-metabolism (2019) (0)
- Statistical Tools for Molecular Covariance Spectroscopy (2017) (0)
- Development and validation of a High Performance Liquid Chromatography-Tandem Mass Spectrometry method for the absolute analysis of 17 α D-amino acids in cooked meals. Authors: (2020) (0)
- Abstract 459: Lipidomic analysis of extracellular vesicles and its potential for the identification of body fluid-based biomarkers for breast cancer diagnosis (2021) (0)
- Metabolic consequences of non-severe burn injury are associated with increased plasma markers of inflammation and cardiovascular disease risk (2023) (0)
- NMR and pattern recognition studies on the biochemistry of black tea-derived polyphenolic compounds in the rat. (2001) (0)
- OP165 Targeted chemical analysis of the colon cancer microbiome using desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) (2016) (0)
- Correction to “Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection” (2021) (0)
- Exploring the Contribution of Metabolic Profiling to Epidemiological Studies (2008) (0)
- Roux-en-Y Gastric bypass-induced bacterial perturbation contributed to an altered metabolic phenotype (2021) (0)
- Microbe-derived indole tunes organ-function and links microbe metabolites to biological ageing (2023) (0)
- The microbial–mammalian metabolic and signalling axis in cardiometabolic diseases (2013) (0)
- The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk (2017) (0)
- Strategy for improved characterization of human metabolic phenotypes using a COmbined Multi-block Principal components Analysis with Statistical Spectroscopy (COMPASS) (2020) (0)
- Faculty Opinions recommendation of Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice. (2010) (0)
- An NMR-Based Model to Investigate the Metabolic Phenoreversion of COVID-19 Patients throughout a Longitudinal Study (2022) (0)
- Early intervention with Bifidobacterium lactis NCC2818 modulates the host-microbe interface independent of the sustained changes induced by the neonatal environment (2017) (0)
- Mas H1 Nmr Assessment of Donor Livers Prior to Transplantation (2004) (0)
- Metabolic Profiling and Population Screening of Analgesic Usage in NMR-Spectroscopy-based Large-scale Epidemiologic Studies (2009) (0)
- Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery (2017) (0)
- Sa1860 - Metabolic Phenotyping of African and Alaskan Indigenous Populations Demonstrates that Urbanization Modifies Gut Microbiome Metabolic Functions Associated with Colon Cancer Risk (2018) (0)
- BASIS: High-performance bioinformatics platform for processing of large-scale mass spectrometry imaging data in chemically augmented histology (2018) (0)
- Roux-en-Y gastric bypass-induced bacterial perturbation contributes to altered host-bacterial co-metabolic phenotype (2021) (0)
- REVIEWS IN BASIC AND CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2014) (0)
- Characterization of diet-dependent temporal changes in circulating short-chain fatty acid concentrations: A randomized crossover dietary trial (2022) (0)
- the Human Microbiome The Application of Ecological Theory Toward an Understanding of (2012) (0)
- Irons status affects non-alcoholic fatty liver disease through the gut microbiome (2021) (0)
- A data-driven approach to identify discriminatory biomarkers from proton nuclear magnetic (NMR) resonance data (2015) (0)
- ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY (UPLC) COUPLED WITH TIME OF FLIGHT MASS SPECTROMETRY FOR COMPLEX MULTI-COMPONENT ANALYSES (2004) (0)
- Abstract P267: Relationship of Coffee Consumption and its Urinary Biomarker to Blood Pressure: The Intermap Study (2013) (0)
- PS-P02-8: HOST GENOMIC INFLUENCE ON THE GUT MICROBIAL METABOLITE-BLOOD PRESSURE RELATIONSHIP (2023) (0)
- 13th Annual meeting of the European Venous Forum, Thursday 28 June–Saturday 30 June 2012, Florence, Italy (2012) (0)
- Functional Insights from Analysis of Biological Fluids (1998) (0)
- Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol (2019) (0)
- Additional file 4: of Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier (2018) (0)
- IMP: Imperial Metagenomics Pipeline for high-throughput sequence data (2015) (0)
- SP1 Mapping of Gut Microbiome-Mammalian Metabolic Interactions by Metabonomics. (2007) (0)
- Models of Inhibition in Biological Networks (2007) (0)
- Faculty Opinions recommendation of Metabonomic evaluation of Schaedler altered microflora rats. (2007) (0)
- UrinaryExcretionof Acetaminophenand Its Metabolitesas Studiedby ProtonNMR Spectroscopy (2004) (0)
- Targeted lipidomics coupled with machine learning for authenticating the provenance of chicken eggs. (2022) (0)
- Ige-facilitated Binding Of Cockroach Allergen-ige Complexes To B Cells: An Assay To Monitor Efficacy During Immunotherapy? (2011) (0)
- Abstract P282: Effects of a Single Unit of Different Alcoholic Beverages on Urinary Excretion Profiles (2013) (0)
- Want to Publish in JPR? This Is What You Need to Know! (2022) (0)
- 1 A Multiplexed Targeted Assay for High-Throughput Quantitative Analysis of Serum 1 Methylamines by Ultra Performance Liquid Chromatography Coupled to High 2 Resolution Mass Spectrometry 3 (0)
- acid-induced fatty liver metabolic approach to understanding orotic An integrated reverse functional genomic and (2015) (0)
- Measurement of longitudinal relaxation times in crowded 1H NMR spectra using one- and two-dimensional maximum quantum (MAXY) NMR spectroscopy (2001) (0)
- Cannulation of the Bile Duct Protects Against Para-Aminophenol-Induced Nephrotoxicity in the Fischer 344 Rat (1989) (0)
- 1H Magic Angle Spinning NMR Spectroscopy of Tissues (2005) (0)
- Biomedical and pharmaceutical chemistry (1991) (0)
- Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women (2018) (0)
- 1106 INVERSE ASSOCIATIONS OF GUT MICROBIAL DERIVED CO-METABOLITES WITH BLOOD PRESSURE: THE INTERMAP STUDY (2012) (0)
- Sa1840 - The Colorectal Cancer Mucosal Microbiome is Defined by Disease Stage and the Tumour Metabonome (2018) (0)
- Application of novel solid phase extraction-NMR protocols for metabolic profiling of human urine. (2019) (0)
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What Schools Are Affiliated With Jeremy Kirk Nicholson?
Jeremy Kirk Nicholson is affiliated with the following schools:
