Jeremy N Rich
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Jeremy N Richcomputer-science Degrees
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Computer Science
Jeremy N Rich's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Jeremy N Rich's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Glioma stem cells promote radioresistance by preferential activation of the DNA damage response (2006) (5832)
- Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. (2007) (1353)
- Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. (2006) (1323)
- Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. (2009) (1203)
- Cancer stem cells in glioblastoma (2015) (1144)
- Phase II Trial of Bevacizumab and Irinotecan in Recurrent Malignant Glioma (2007) (1067)
- Phase II trial of gefitinib in recurrent glioblastoma. (2004) (747)
- The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype (2009) (726)
- Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth (2013) (725)
- Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis. (2008) (723)
- Making a tumour's bed: glioblastoma stem cells and the vascular niche (2007) (703)
- Periostin Secreted by Glioblastoma Stem Cells Recruits M2 Tumor-associated Macrophages and Promotes Malignant Growth (2014) (651)
- Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells. (2013) (628)
- Integrin alpha 6 regulates glioblastoma stem cells. (2010) (627)
- Notch Promotes Radioresistance of Glioma Stem Cells (2009) (612)
- Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. (2004) (509)
- Cancer stem cells in radiation resistance. (2007) (480)
- Distinct requirements for Ras oncogenesis in human versus mouse cells. (2002) (465)
- HIF induces human embryonic stem cell markers in cancer cells. (2011) (461)
- Hypoxia inducible factors in cancer stem cells (2010) (419)
- Challenges to curing primary brain tumours (2019) (414)
- Targeting cancer stem cells through L1CAM suppresses glioma growth. (2008) (401)
- c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells (2008) (383)
- Brain Tumor Initiating Cells Adapt to Restricted Nutrition through Preferential Glucose Uptake (2013) (381)
- A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo. (2016) (368)
- Acidic stress promotes a glioma stem cell phenotype (2011) (343)
- Molecularly targeted therapy for malignant glioma (2007) (330)
- Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme. (2005) (326)
- Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth (2009) (324)
- High-Speed Coherent Raman Fingerprint Imaging of Biological Tissues (2014) (320)
- Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. (2017) (320)
- Gene expression profiling and genetic markers in glioblastoma survival. (2005) (318)
- Recent advances in the treatment of malignant astrocytoma. (2006) (318)
- Cancer Stem Cells: The Architects of the Tumor Ecosystem. (2019) (311)
- Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2 (2011) (304)
- Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth (2012) (299)
- Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A (2013) (279)
- Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. (2008) (277)
- Mitochondrial Control by DRP1 in Brain Tumor Initiating Cells (2015) (276)
- Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. (2009) (273)
- Development of novel targeted therapies in the treatment of malignant glioma (2004) (270)
- Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. (2002) (262)
- Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. (2000) (259)
- Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition. (2005) (255)
- Brain Cancer Stem Cells Display Preferential Sensitivity to Akt Inhibition (2008) (243)
- Phase II trial of temozolomide in patients with progressive low-grade glioma. (2003) (243)
- Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. (2011) (242)
- Targeting Glioma Stem Cells through Combined BMI1 and EZH2 Inhibition (2017) (240)
- Progress Report of a Phase I Study of the Intracerebral Microinfusion of a Recombinant Chimeric Protein Composed of Transforming Growth Factor (TGF)-α and a Mutated form of the Pseudomonas Exotoxin Termed PE-38 (TP-38) for the Treatment of Malignant Brain Tumors (2003) (240)
- Deadly teamwork: neural cancer stem cells and the tumor microenvironment. (2011) (228)
- Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer (2019) (226)
- Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma. (2010) (211)
- SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility. (2004) (207)
- Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells. (2015) (203)
- Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance. (2015) (199)
- Potential therapeutic implications of cancer stem cells in glioblastoma. (2010) (195)
- Phase 1 Trial of Gefitinib Plus Sirolimus in Adults with Recurrent Malignant Glioma (2006) (193)
- Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma. (2002) (188)
- Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results. (2006) (186)
- N 6 -methyladenine DNA Modification in Glioblastoma (2018) (183)
- Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions (2011) (180)
- A novel low‐molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth (2007) (179)
- Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness. (2010) (178)
- Elevated invasive potential of glioblastoma stem cells. (2011) (175)
- Bevacizumab Plus Irinotecan in Recurrent WHO Grade 3 Malignant Gliomas (2008) (174)
- Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth (2017) (170)
- Resistance to Tyrosine Kinase Inhibition by Mutant Epidermal Growth Factor Receptor Variant III Contributes to the Neoplastic Phenotype of Glioblastoma Multiforme (2004) (169)
- Cancer Stem Cell‐Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion (2016) (167)
- Bone-related Genes Expressed in Advanced Malignancies Induce Invasion and Metastasis in a Genetically Defined Human Cancer Model* (2003) (162)
- Cancer Stem Cell‐Specific Scavenger Receptor CD36 Drives Glioblastoma Progression (2014) (162)
- L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1 (2011) (160)
- Brain tumor stem cells: Molecular characteristics and their impact on therapy. (2014) (158)
- Therapeutic Targeting of Ependymoma as Informed by Oncogenic Enhancer Profiling (2017) (157)
- A genetically tractable model of human glioma formation. (2001) (157)
- MET signaling regulates glioblastoma stem cells. (2012) (155)
- AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells. (2018) (153)
- Biology of glioma cancer stem cells (2009) (152)
- Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells (2013) (152)
- Chemotherapy and cancer stem cells. (2007) (150)
- Glioblastoma Stem Cells: Driving Resilience through Chaos. (2020) (148)
- Laminin alpha 2 enables glioblastoma stem cell growth (2012) (147)
- Transcription elongation factors represent in vivo cancer dependencies in glioblastoma (2017) (147)
- Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells (2011) (145)
- Cancer stem cells in gliomas: Identifying and understanding the apex cell in cancer's hierarchy (2011) (144)
- Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy. (2017) (141)
- Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases (2007) (141)
- Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression. (2018) (138)
- Functional Enhancers Shape Extrachromosomal Oncogene Amplifications (2019) (136)
- Cancer stem cells: understanding tumor hierarchy and heterogeneity (2016) (132)
- EphA2 Promotes Infiltrative Invasion of Glioma Stem Cells in vivo through Crosstalk with Akt and Regulates Stem Properties (2014) (130)
- Hypoxia and hypoxia inducible factors in cancer stem cell maintenance. (2010) (128)
- Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential (2011) (127)
- Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival. (2011) (127)
- Purine synthesis promotes maintenance of brain tumor initiating cells in glioma (2017) (125)
- The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells. (2020) (124)
- Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy (2009) (123)
- Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy (2014) (122)
- The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma (2015) (122)
- Turning Cancer Stem Cells Inside Out: An Exploration of Glioma Stem Cell Signaling Pathways* (2009) (120)
- Phase II trial of irinotecan plus celecoxib in adults with recurrent malignant glioma (2005) (120)
- Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth (2010) (119)
- Using a stem cell-based signature to guide therapeutic selection in cancer. (2011) (117)
- Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock. (2019) (116)
- Secreted Protein Acidic, Rich in Cysteine (SPARC), Mediates Cellular Survival of Gliomas through AKT Activation* (2004) (116)
- Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity. (2012) (115)
- New treatment strategies for malignant gliomas (2006) (114)
- Notch signaling in cancer stem cells. (2012) (114)
- Designer Therapies for Glioblastoma Multiforme (2008) (113)
- Zika virus has oncolytic activity against glioblastoma stem cells (2017) (109)
- Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. (2019) (107)
- Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas (2007) (107)
- miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma (2013) (104)
- ZD6474, a Novel Tyrosine Kinase Inhibitor of Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor, Inhibits Tumor Growth of Multiple Nervous System Tumors (2005) (102)
- Diagnosis and treatment of high-grade astrocytoma. (2007) (101)
- Sema3C promotes the survival and tumorigenicity of glioma stem cells through Rac1 activation. (2014) (99)
- Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination (2017) (98)
- Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling. (2019) (96)
- A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost. (2008) (95)
- High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas. (2003) (94)
- Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance (2018) (94)
- Differential Connexin Function Enhances Self-Renewal in Glioblastoma (2014) (94)
- Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions (2020) (92)
- Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells. (2013) (92)
- MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin. (2015) (92)
- Transforming Growth Factor-β-mediated p15INK4BInduction and Growth Inhibition in Astrocytes Is SMAD3-dependent and a Pathway Prominently Altered in Human Glioma Cell Lines* (1999) (89)
- Tumor cells upregulate normoxic HIF-1α in response to doxorubicin. (2013) (89)
- Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair (2012) (86)
- Glioma Stem Cell Specific Super Enhancer Promotes Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling. (2019) (86)
- Bevacizumab continuation beyond initial bevacizumab progression among recurrent glioblastoma patients (2012) (84)
- Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis. (2019) (82)
- Deubiquitinase HAUSP Stabilizes REST and Promotes Maintenance of Neural Progenitor Cells (2010) (82)
- MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells. (2017) (80)
- Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma (2020) (80)
- An epigenetic gateway to brain tumor cell identity (2015) (79)
- Glioma stem cell maintenance: the role of the microenvironment. (2011) (78)
- Cancer stem cells in brain tumor biology. (2008) (77)
- Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance. (2010) (77)
- Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells (2019) (77)
- β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma. (2013) (76)
- Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression. (2014) (76)
- Profilin-1 Phosphorylation Directs Angiocrine Expression and Glioblastoma Progression through HIF-1α Accumulation (2014) (76)
- The role of transforming growth factor-beta in primary brain tumors. (2003) (74)
- The evolving landscape of glioblastoma stem cells. (2013) (74)
- Hyperthermia Sensitizes Glioma Stem-like Cells to Radiation by Inhibiting AKT Signaling. (2015) (74)
- Nicotinamide metabolism regulates glioblastoma stem cell maintenance. (2017) (72)
- Twisted tango: brain tumor neurovascular interactions (2011) (71)
- High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor. (2014) (70)
- Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme. (1992) (68)
- Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma (2011) (68)
- Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma. (2008) (67)
- Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events (2017) (66)
- Malignant glioma drug discovery – targeting protein kinases (2007) (66)
- Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma (2020) (66)
- Development of a Fluorescent Reporter System to Delineate Cancer Stem Cells in Triple‐Negative Breast Cancer (2015) (64)
- Cancer stem cells: master gatekeepers and regulators of cancer growth and metastasis Introduction (2016) (61)
- Autocrine VEGF-VEGFR2—Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth (2012) (59)
- Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models. (2016) (57)
- Aptamer identification of brain tumor-initiating cells. (2013) (57)
- Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma (2019) (55)
- Chemotherapy and novel therapeutic approaches in malignant glioma. (2005) (55)
- NDRG4 Is Required for Cell Cycle Progression and Survival in Glioblastoma Cells* (2009) (54)
- Phase II Trial of Gliadel plus O6-Benzylguanine in Adults with Recurrent Glioblastoma Multiforme (2009) (54)
- Tetraspanin CD9 stabilizes gp130 by preventing its ubiquitin-dependent lysosomal degradation to promote STAT3 activation in glioma stem cells (2016) (53)
- Improving the radiosensitivity of radioresistant and hypoxic glioblastoma. (2010) (52)
- Enhancement of Nitrosourea Activity in Medulloblastoma and Glioblastoma Multiforme (1992) (52)
- A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. (2019) (52)
- New approaches to primary brain tumor treatment (2006) (51)
- Antiangiogenic therapy in malignant glioma: promise and challenge. (2007) (51)
- Transforming growth factor‐β signaling in cancer (2001) (50)
- AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma. (2006) (49)
- Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma. (2004) (49)
- Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant glioma: phase I trial results. (2006) (46)
- EGFR mutations and sensitivity to gefitinib. (2004) (46)
- RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation. (2016) (46)
- Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity. (2005) (45)
- CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies. (2020) (45)
- CDC20 maintains tumor initiating cells (2015) (44)
- The Zinc Finger Transcription Factor ZFX Is Required for Maintaining the Tumorigenic Potential of Glioblastoma Stem Cells (2014) (44)
- Chromosomal Instability Affects the Tumorigenicity of Glioblastoma Tumor-Initiating Cells. (2016) (44)
- Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma. (2008) (44)
- Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma. (2019) (44)
- The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion (2007) (44)
- Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value (2017) (42)
- Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth (2015) (42)
- Seeing is Believing: Are Cancer Stem Cells the Loch Ness Monster of Tumor Biology? (2011) (40)
- Phase 1 trial of dasatinib plus erlotinib in adults with recurrent malignant glioma (2012) (40)
- Second messenger systems in human gliomas. (2007) (40)
- The ID1-CULLIN3 Axis Regulates Intracellular SHH and WNT Signaling in Glioblastoma Stem Cells. (2016) (39)
- Role of cysteine-rich 61 protein (CCN1) in macrophage-mediated oncolytic herpes simplex virus clearance. (2014) (39)
- Biomaterials and 3D Bioprinting Strategies to Model Glioblastoma and the Blood–Brain Barrier (2020) (39)
- Messenger RNA Methylation Regulates Glioblastoma Tumorigenesis. (2017) (37)
- Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities (2022) (37)
- The Emerging Role of Anti-Angiogenic Therapy for Malignant Glioma† (2008) (37)
- Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma. (2009) (35)
- Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma. (2012) (35)
- Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase (2020) (34)
- Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches (2019) (32)
- Autocrine VEGF – VEGFR 2 – Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth (2012) (32)
- Glioblastoma Stem Cells: A Neuropathologist's View (2010) (32)
- Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling. (2016) (32)
- Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines. (1999) (31)
- Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low‐grade glioma (2012) (31)
- Bevacizumab, a monoclonal antibody to vascular endothelial growth factor (VEGF), and irinotecan for treatment of malignant gliomas. (2006) (31)
- Mechanism of Action of Methotrexate Against Zika Virus (2018) (30)
- Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells (2014) (30)
- Squelching glioblastoma stem cells by targeting REST for proteasomal degradation (2009) (30)
- Lyn Facilitates Glioblastoma Cell Survival under Conditions of Nutrient Deprivation by Promoting Autophagy (2013) (30)
- Update on survival from the original phase II trial of bevacizumab and irinotecan in recurrent malignant gliomas (2008) (29)
- Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin (2020) (29)
- Chromatin remodeler HELLS maintains glioma stem cells through E2F3 and MYC. (2019) (28)
- Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade. (2020) (28)
- Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation (2020) (27)
- APOE4-VLDL Inhibits the HDL-Activated Phosphatidylinositol 3-Kinase/Akt Pathway via the Phosphoinositol Phosphatase SHIP2 (2006) (27)
- Cadherin-11 Regulates Motility in Normal Cortical Neural Precursors and Glioblastoma (2013) (27)
- Vandetanib, a novel multitargeted kinase inhibitor, in cancer therapy. (2006) (27)
- Outcome after bevacizumab clinical trial therapy among recurrent grade III malignant glioma patients (2012) (27)
- Tax-interacting protein 1 coordinates the spatiotemporal activation of Rho GTPases and regulates the infiltrative growth of human glioblastoma (2013) (27)
- Development of a Sox2 reporter system modeling cellular heterogeneity in glioma. (2015) (26)
- PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response (2020) (26)
- Phage display discovery of novel molecular targets in glioblastoma-initiating cells (2014) (26)
- Medical oncology: Treatment and management of malignant gliomas (2010) (25)
- Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells (2016) (25)
- Glioma Development: Where Did It All Go Wrong? (2011) (25)
- Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug (2021) (24)
- FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells (2020) (24)
- New Advances and Challenges of Targeting Cancer Stem Cells. (2017) (24)
- Genomics informs glioblastoma biology (2013) (24)
- Multiplex Flow Cytometry Barcoding and Antibody Arrays Identify Surface Antigen Profiles of Primary and Metastatic Colon Cancer Cell Lines (2013) (24)
- Inhibition of ID1–BMPR2 Intrinsic Signaling Sensitizes Glioma Stem Cells to Differentiation Therapy (2017) (23)
- Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma. (2004) (23)
- Acquisition of meiotic DNA repair regulators maintain genome stability in glioblastoma (2015) (22)
- Decoding the cancer stem cell hypothesis in glioblastoma. (2013) (22)
- The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina. (2014) (22)
- SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells (2020) (22)
- Type I Interferon Regulates a Coordinated Gene Network to Enhance Cytotoxic T Cell-Mediated Tumor Killing. (2020) (21)
- A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function (2018) (20)
- The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies. (2020) (19)
- The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking (2017) (19)
- Inhibiting DNA-PK induces glioma stem cell differentiation and sensitizes glioblastoma to radiation in mice (2021) (19)
- Bacterial flavohemoglobin: a molecular tool to probe mammalian nitric oxide biology. (2011) (18)
- Feedback circuitry between miR-218 repression and RTK activation in glioblastoma (2015) (18)
- Poly(ADP‐Ribose) Polymerase Inhibition Sensitizes Colorectal Cancer‐Initiating Cells to Chemotherapy (2018) (17)
- The dystroglycan receptor maintains glioma stem cells in the vascular niche (2019) (17)
- Final report: Phase I trial of imatinib mesylate, hydroxyurea, and vatalanib for patients with recurrent malignant glioma (MG) (2008) (16)
- Failure of human rhombic lip differentiation underlies medulloblastoma formation (2022) (16)
- Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme. (2007) (16)
- Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma (2017) (16)
- Lgr5 Marks Post-Mitotic, Lineage Restricted Cerebellar Granule Neurons during Postnatal Development (2014) (15)
- International Hermelin brain tumor symposium on matricellular proteins in normal and cancer cell-matrix interactions. (2004) (15)
- Bevacizumab and daily temozolomide for recurrent glioblastoma multiforme (GBM) (2008) (15)
- Pharmacokinetic drug interaction between AEE788 and RAD001 causing thrombocytopenia in patients with glioblastoma (2011) (14)
- Targeting A 20 Decreases Glioma Stem Cell Survival and Tumor Growth (2010) (14)
- Phase II trial of bevacizumab and irinotecan in the treatment of malignant gliomas (2007) (14)
- The Quest for Self-Identity: Not All Cancer Stem Cells Are the Same (2012) (14)
- ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance (2022) (13)
- The tailless root of glioma: cancer stem cells. (2014) (13)
- Treatment of Glioblastoma Using Multicomponent Silica Nanoparticles (2019) (13)
- Phase II study of bevacizumab plus erlotinib for recurrent malignant gliomas. (2009) (13)
- Phase II study of bevacizumab and erlotinib in patients with recurrent glioblastoma multiforme (2008) (13)
- Phase I trial of imatinib mesylate, hydroxyurea and vatalanib for patients with recurrent glioblastoma multiforme (GBM) (2007) (12)
- Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity (2022) (12)
- Targeting glioma-initiating cells in GBM: ABTC-0904, a randomized phase 0/II study targeting the Sonic Hedgehog-signaling pathway. (2014) (12)
- Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells. (2021) (12)
- Effect of bevacizumab (BEV) and irinotecan (CPT-11) on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in glioblastoma (GBM) patients (2008) (11)
- Satellite DNA and related diseases (2014) (11)
- Long-term survival from the initial trial of bevacizumab and irinotecan. (2010) (11)
- The Implications of the Cancer Stem Cell Hypothesis for Neuro-Oncology and Neurology. (2008) (11)
- Phase II open-label, safety, pharmacokinetic and efficacy study of 2-methoxyestradiol nanocrystal colloidal dispersion administered orally to patients with recurrent glioblastoma multiforme (2007) (11)
- Correction: Zika virus has oncolytic activity against glioblastoma stem cells (2017) (11)
- A phase I trial of imatinib, hydroxyurea and RAD001 for patients with recurrent malignant glioma. (2006) (11)
- Plasma cells shape the mesenchymal identity of ovarian cancers through transfer of exosome-derived microRNAs (2021) (11)
- Overall survival of primary glioblastoma (GBM) patients (pts) receiving carmustine (BCNU) wafers followed by radiation (RT) and concurrent temozolomide (TMZ) plus rotational multi-agent chemotherapy (2007) (11)
- Mitotic control of cancer stem cells. (2013) (10)
- Phase II study of bevacizumab and etoposide in patients with recurrent malignant glioma (2008) (10)
- USP33 deubiquitinates and stabilizes HIF‐2alpha to promote hypoxia response in glioma stem cells (2022) (10)
- Dynamic and transient cancer stem cells nurture melanoma (2010) (10)
- Protein Sumoylation with SUMO1 Promoted by Pin1 in Glioma Stem Cells Augments Glioblastoma Malignancy. (2020) (10)
- PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine. (2022) (9)
- An update on phase I study of dose-escalating imatinib mesylate plus standard-dosed temozolomide for the treatment of patients with malignant glioma. (2006) (9)
- A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells. (2022) (9)
- Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice. (2017) (8)
- Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) evaluation in glioblastoma (GBM) patients treated with bevacizumab (BEV) and irinotecan (CPT-11) (2007) (8)
- Molecularly targeted therapy in neuro-oncology. (2012) (8)
- Looking in the miR-ror: TGF-β-mediated activation of NF-κB in glioma. (2012) (8)
- Phase II trial of erlotinib plus sirolimus for recurrent glioblastoma multiforme (GBM) (2008) (7)
- Acute toxicity analysis of patients receiving surgery, Gliadel wafer implantation, and postoperative daily temozolomide with radiation therapy for primary high-grade glioma. (2006) (7)
- Growth factor receptors define cancer hierarchies. (2013) (7)
- TARGETING GLIOMA INITIATING CELLS IN GBM: ABTC-0904, A RANDOMIZED PHASE 0/II STUDY TARGETING THE SONIC HEDGEHOG-SIGNALING PATHWAY (2014) (7)
- A phase I trial of gefitinib (ZD1839) plus rapamycin for patients with recurrent malignant glioma (2005) (7)
- Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells. (2019) (7)
- Brain Cancer Stem Cells as Targets of Novel Therapies (2009) (7)
- Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases (2022) (7)
- Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches (2021) (7)
- Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome (2022) (7)
- Efficacy of imatinib mesylate plus hydroxyurea regimen in the treatment of recurrent malignant glioma: Phase II study results (2005) (6)
- Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle (2023) (6)
- Zika Virus Is Transmitted in Neural Progenitor Cells via Cell-to-Cell Spread, and Infection Is Inhibited by the Autophagy Inducer Trehalose (2020) (6)
- β2-microglobulin maintains glioblastoma stem cells and induces M2-like polarization of tumor-associated macrophages. (2022) (6)
- Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe (2021) (5)
- Impact on Health-Related Quality of Life of Induction Chemotherapy Compared With Concurrent Cisplatin and Radiation Therapy in Patients With Head and Neck Cancer. (2019) (5)
- Phase II trial of Gliadel plus O6-benzylguanine (O6-BG) for patients with recurrent glioblastoma multiforme. (2006) (5)
- Combination of bevacizumab, a monoclonal antibody to vascular endothelial growth factor (VEGF), and temozolomide: Study of cases. (2006) (5)
- Phage display targeting identifies EYA1 as a regulator of glioblastoma stem cell maintenance and proliferation (2021) (5)
- A novel low molecular weight inhibitor of focal adhesion kinase and insulin-like growth factor-1 receptor, TAE226, inhibits glioma growth. (2006) (5)
- CLIN-ONGOING CLINICAL TRIALS (2012) (5)
- Meningioma epigenetic grouping reveals biologic drivers and therapeutic vulnerabilities (2020) (5)
- The landscape of extrachromosomal circular DNA in medulloblastoma (2021) (5)
- Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells (2019) (5)
- TRP-ing up brain tumors (2012) (4)
- Phase II trial of iodine 131-labeled murine anti-tenascin monoclonal anti-body 81C6 (M81C6) via surgically created resection cavity in the treatment of patients with recurrent malignant brain tumors. (2004) (4)
- Molecular Targeting of Neural Cancer Stem Cells: TTAGGG, You're It! (2011) (4)
- Cancer stem cells A nuanced perspective (2016) (4)
- Cancer Cell Signaling: Methods and Protocols (2003) (4)
- A phase I dose escalation study of imatinib mesylate plus standard-dosed temozolomide in the treatment of patients with malignant glioma (2005) (4)
- CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity (2022) (4)
- Holding on to stemness (2012) (4)
- Phase II trial of imatinib mesylate and hydroxyurea for grade III malignant gliomas. (2006) (3)
- Cancer stem cells (2016) (3)
- Transforming Growth Factor-b-mediated p 15 INK 4 B Induction and Growth Inhibition in Astrocytes Is SMAD 3-dependent and a Pathway Prominently Altered in Human Glioma Cell Lines (1999) (3)
- SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus (2022) (3)
- 3 TGF-β: A Multipotential Cytokine (2008) (3)
- A delicate initiation: Lipolysis of lipid droplets fuels glioblastoma. (2021) (3)
- Phase II trial of imatinib mesylate and hydroxyurea for adults with recurrent/progressive low-grade glioma (2007) (2)
- The cancer stem cell: a new therapeutic paradigm? (2006) (2)
- HAUSP Stabilizes SOX2 through Deubiquitination to Maintain Self-renewal and Tumorigenic Potential of Glioma Stem Cells (2021) (2)
- Changing the fate of cancer, one splice at a time (2013) (2)
- Growth factor receptor signaling induces mitophagy through epitranscriptomic regulation (2022) (2)
- CELL BIOLOGY AND SIGNALING (2010) (2)
- Multicenter phase II trial of nab-paclitaxel and cisplatin (AP) followed by chemoradiation therapy (CRT) for locally advanced head and neck squamous cell carcinoma (HNSCC). (2018) (2)
- The effect ofl-amino acid oxidase on activity of melphalan against an intracranial xenograft (2004) (2)
- A vaccine for glioma (2021) (2)
- Capturing cancer stem cells (2008) (2)
- Phase I trial of temozolomide plus O6-benzylguanine on three different 5-day temozolomide regimens for patients with progressive glioblastoma multiforme (2008) (2)
- Tinzaparin prophylaxis in brain tumor patients (2007) (2)
- Patient-derived explants as tumor models. (2022) (2)
- Secreted protein acidic and rich in cysteine (SPARC) activates focal adhesion kinase and integrin-linked kinase to induce AKT-dependent glioma survival and invasion (2006) (2)
- APOE 4-VLDL Inhibits the HDL-Activated Phosphatidylinositol 3-Kinase / Akt Pathway via the Phosphoinositol Phosphatase SHIP 2 (2006) (2)
- Radiation and concurrent temozolomide followed by rotational multi-agent chemotherapy for glioblastoma (GBM) patients (2007) (2)
- Transcription Factor Complex Mediates IGF-I Receptor Signaling and Predicts Poor Prognosis in Lung Adenocarcinoma (2013) (1)
- Glioma stem cells activate platelets by plasma-independent thrombin production to promote glioblastoma tumorigenesis (2022) (1)
- Neurofibromatosis type 2 (2007) (1)
- Abstract 320: 3D-bioprinting of biomimetic multicellular glioblastoma tissues enable modeling of tumor-immune interactions (2020) (1)
- Results of a phase II trial with iodine 131-labeled murine antitenascin monoclonal antibody 81C6 (m81C6) via surgically created resection cavities in the treatment of patients with recurrent malignant brain tumors (2004) (1)
- Abstract 3311: IL6-Stat3 signaling promotes glioma stem cell (GSC) survival under hypoxia environment through inhibition of cell-death inducing gene Bnip3 (2011) (1)
- PTEN hamartomatous tumor syndromes (2006) (1)
- Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling (2022) (1)
- Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma (2021) (1)
- b -Catenin/POU5F1/SOX2 Transcription Factor Complex Mediates IGF-I Receptor Signaling and Predicts Poor Prognosis in Lung Adenocarcinoma (2013) (1)
- Reprogramming the microenvironment: tricks of tumor-derived astrocytes (2020) (1)
- Stem Cell Pathways in Brain Tumors (2012) (1)
- GLIOBLASTOMA STEM CELL-DERIVED PERICYTES AND TUMOR ANGIOGENESIS (2014) (1)
- Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions (2020) (1)
- CBMT-47. THE ROLE OF PHOSPHOFRUCTOKINASE-1 IN GLIOBLASTOMA MAINTENANCE AND MOTILITY (2018) (1)
- Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome (2022) (1)
- DNA Repair mechanisms in glioblastoma cancer stem cells (2013) (1)
- Single-cell Transcriptomics Resolves Intermediate Glial Progenitors and Uncovers a Pivotal Determinant of Cell Fate and Gliomagenesis (2019) (1)
- Targeting Microglial Metabolic Rewiring Synergizes with Immune Checkpoint Blockade Therapy for Glioblastoma. (2023) (1)
- 361 WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma (2021) (1)
- Brain Tumor Stem Cell Markers (2009) (1)
- Efficacy and immunologic effects of RNA-pulsed dendritic cell vaccines targeting human cytomegalovirus antigens in patients with glioblastoma (2008) (1)
- "PEAR-ing" Genomic and Epigenomic Analyses for Cancer Gene Discovery. (2015) (1)
- Abstract 3898: Glioma stem cells promote brain endothelial cell motility: a new mechanism for the direct interaction of glioma stem cells with endothelial cells. (2013) (1)
- Abstract 5205: Iron metabolism informs glioblastoma stem cell maintenance (2012) (1)
- Transforming Growth Factor-b-mediated p15 Induction and Growth Inhibition in Astrocytes Is SMAD3-dependent and a Pathway Prominently Altered in Human Glioma Cell Lines* (1999) (1)
- ME-15INTERACTION BETWEEN CANCER STEM CELLS AND MYELOID DERIVED SUPPRESSOR CELLS DRIVES IMMUNOSUPPRESSION AND GLIOBLASTOMA GROWTH. (2014) (1)
- SUFU: The Jekyll and Hyde of the Cerebellum. (2019) (1)
- Mouse cell depletion (2015) (1)
- Growth Factor Receptor Fusions Predict Therapeutic Sensitivity (2015) (1)
- ABERRANT SPLICING OF A BRAIN-ENRICHED ALTERNATIVE EXON ELIMINATES TUMOR SUPPRESSOR FUNCTION AND PROMOTES ONCOGENE FUNCTION DURING BRAIN TUMORIGENESIS (2014) (0)
- Abstract 5725: Epigenetic and transcriptional profiling reveal endosomal protein sorting as a glioblastoma cancer stem cell dependency (2020) (0)
- CBIO-28NIX PROMOTES GLIOBLASTOMA CELL SURVIVAL UNDER STRESS THROUGH MITOPHAGY (2015) (0)
- The Rationale for and Effects of Targeting TGF-β for Glioma Therapy (2008) (0)
- Hijacking a neurodevelopmental epigenomic program in metastatic dissemination of medulloblastoma (2022) (0)
- Abstract 4178: L1CAM and integrin αvβ3 mediate direct cell contact between cancer stem cells and endothelial cells: Promotion of endothelial cell migration and survival (2015) (0)
- OMRT-14. Small molecule circadian clock compounds exhibit potential as a novel therapy paradigm for glioblastoma (2021) (0)
- SPARC/Osteonectin expression induces glioma invasion and survival under serum-free conditions (2004) (0)
- Abstract 3327: Leptin receptors are expressed in breast cancer stem cells and leptin promotes their self-renewal and survival in mice (2011) (0)
- Irinotecan T herapy i n A dults W ith R ecurrent o r P rogressive Malignant G lioma (1999) (0)
- High-Dose C hemotherapy W ith A utologous S tem-Cell R escue in C hildren a nd A dults W ith N ewly D iagnosed P ineoblastomas (2003) (0)
- SC-13ID1-CULLIN3 AXIS REGULATES STEM CELL SIGNALING IN GLIOMA (2014) (0)
- STEM-15. IDENTIFYING NICHE-INDEPENDENT PRO-TUMORIGENIC FACTORS IN GLIOBLASTOMA (2017) (0)
- STEM-08. RNA BINDING PROTEIN ZFP36L2 REGULATES GLIOMA STEM CELL MAINTENANCE (2017) (0)
- Summary Dysregulated growth factor pathways promote tumor growth in many cancers (2015) (0)
- SC-08TRANSCRIPTIONAL AND POST-TRANSLATIONAL REGULATIONS OF c-Myc IN GLIOBLASTOMA STEM CELLS. (2014) (0)
- SC-32TARGETING PROLIFERATION AND INVASION IN GLIOBLASTOMA VIA MITOTIC KINESINS (2014) (0)
- IN THE SPOTLIGHT Mitotic Control of Cancer Stem Cells (2013) (0)
- 621 POSTER A phase I study of combination therapy with AEE788, a novel multitargeted inhibitor of ErbB and VEGF receptor family tyrosine kinases, and RAD001, a mTOR inhibitor in recurrent GBM patients (2006) (0)
- PDGF Signaling Promotes Mitophagy in Glioblastoma Stem Cells Through N 6-Methyladenosine (2021) (0)
- STEM-04. PLATELETS DRIVE GLIOBLASTOMA ONCOGENESIS BY ENHANCING THE GLIOMA STEM CELL PHENOTYPE (2020) (0)
- IMMU-47. HARNESSING ZIKA VIRUS (ZIKV) ONCOLYTIC ACTIVITY IN BRAIN TUMORS (2018) (0)
- CBIO-21. DNA HELICASE HELLS MAINTAINS GLIOMA STEM CELLS (2017) (0)
- Phase II Trial of Gliadel plus O 6-Benzylguanine in Adults with Recurrent GlioblastomaMultiforme (2009) (0)
- Stem Cell Markers As Determinants Of Rectal Cancer Recurrence (2011) (0)
- Tumor and Stem Cell Biology MET Signaling Regulates Glioblastoma Stem Cells (2012) (0)
- Direct Visualization of Tumor Propagation by Cancer Stem Cells and Associated Tissue Responses (2011) (0)
- STEM-18. RENIN-ANGIOTENSIN SYSTEM IDENTIFIED BY PHAGE DISPLAY SCREENING IS A NEW THERAPEUTIC TARGET FOR GLIOBLASTOMA AND REGULATES PROLIFERATION OF GLIOBLASTOMA STEM CELLS (2017) (0)
- Constitutive Activation of Ras and Inactivation of Ink4a/Arf Allele Induce a Fully Penetrant B-Cell Acute Lymphoblastic Leukemia Phenotype in Mice (2017) (0)
- Abstract P2-06-01: Development of a fluorescent reporter system to delineate self-renewing cells in triple negative breast cancer (2015) (0)
- TMOD-16. MODELING GLIOBLASTOMA THROUGH CANCER STEM CELL ORGANOIDS (2017) (0)
- STEM-14. RSAD1 IS A NOVEL TARGET IMPLICATED IN THE GLIOBLASTOMA STEM CELL STRESS RESPONSE (2017) (0)
- Abstract 3276: The tissue and cellular destination of therapeutic IgGs in glioblastoma (2016) (0)
- Phase II study of thalidomide and daily cyclophosphamide for adults with malignant glioma. (2004) (0)
- STEM-12. TARGETING GLIOMA STEM CELL MIRNA NETWORKS (2017) (0)
- Abstract C13: Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth (2009) (0)
- MANAGEMENT PERSPECTIVE (2010) (0)
- Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma (2020) (0)
- NIR Drives Glioblastoma Growth by Promoting Ribosomal DNA Transcription in Glioma Stem Cells. (2022) (0)
- STEM-06. NUCLEAR STRUCTURE MAINTAINS GLIOBLASTOMA STEM CELLS (2022) (0)
- Abstract 3370: DNA repair in glioma stem cell-mediated radiation resistance (2012) (0)
- tolerabil-Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme 1 Neuro-oNcology (2006) (0)
- Abstract 505: Small molecule circadian clock compounds display therapeutic potential in targeting glioblastoma stem cells (2023) (0)
- TMET-09. LOSS OF MAT2A COMPROMISES METHIONINE METABOLISM AND REPRESENTS A VULNERABILITY IN H3K27M MUTANT GLIOMAS (2022) (0)
- Na-K-2CI Cotransport in Intestinal Epithelial Cells (2001) (0)
- Semaphorin 3C Mediates Glioma Stem Cell Tumorigenicity (2015) (0)
- EPCO-36. GENOMIC INSTABILITY AND TRANSCRIPTOMIC SIGNATURES UNDERLYING EPIGENETIC MENINGIOMA SUBGROUPS REVEALS MECHANISMS OF IMMUNE INFILTRATION AND THERAPEUTIC VULNERABILITIES (2020) (0)
- MEDU-22. IDENTIFYING DRIVERS OF CHEMORESISTANCE IN GROUP 3 MEDULLOBLASTOMA THROUGH A CRISPR/CAS9 GENOME-WIDE ACTIVATION SCREEN (2017) (0)
- TMOD-13. RESEARCH RESOURCES FOR OLIGODENDROGLIOMA NOW AVAILABLE TO RESEARCH COMMUNITY (2020) (0)
- STEM-03. NOVEL METASTATIC BRAIN TUMOR TARGETS ISOLATED THROUGH PHAGE DISPLAY BIOPANNING AGAINST BRAIN METASTASIS-INITIATING CELLS (2018) (0)
- CBIO-20GLIOBLASTOMA SPECIFIC PROTEINS IDENTIFIED THROUGH COMBINED IN VITRO AND IN VIVO PHAGE DISPLAY BIOPANNING (2015) (0)
- Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma 1 (2004) (0)
- Tinzaparin prophylaxis against thromboembolic complications in brain tumor patients. (2006) (0)
- GLIOBLASTOMA SPECIFIC PROTEINS IDENTIFIED THROUGH COMBINED IN VITRO AND IN VIVO PHAGE (2015) (0)
- Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation (2022) (0)
- Radiosensitization of Glioblastoma Stem Cells by Targeting High-affinity Glucose Uptake (S43.001) (2015) (0)
- Prevalence of osteoporosis in glioma patients on enzyme inducing anticonvulsants (EIAC) and/or glucocorticoids (2007) (0)
- Thermoradiation Therapy Targets Glioblastoma Initiating Cells Through Downregulation of AKT (2013) (0)
- ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449 (2022) (0)
- SP143 Cancer stem cells and the microenvironment: The role of hypoxia (2009) (0)
- TMIC-01. THE DYSTROGLYCAN RECEPTOR MAINTAINS GLIOMA STEM CELLS IN THE VASCULAR NICHE (2019) (0)
- Hyperthermia Sensitizes Glioma Stem Cells to Radiation by Inhibiting AKT (2015) (0)
- Bayesian analysis of gene expression profiles links invasion related genes to poor survival in older glioblastoma patients (2005) (0)
- Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting (2023) (0)
- Abstract A45: Semaphorin 3C mediates glioma stem cell tumorigenicity and radioresistance (2015) (0)
- SREBP2 maintains glioblastoma stem cells through keeping the balance between cholesterol biosynthesis and uptake. (2023) (0)
- Integration of cancer stem cell maintenance and lipid metabolism by scavenger receptors. (2014) (0)
- AND COMPROMISES GLIOBLASTOMA (2014) (0)
- Radiosensitization of Glioblastoma Stem Cells through Targeting Metabolic Reprogramming. (2016) (0)
- A neurodevelopmental epigenetic programme mediated by SMARCD3–DAB1–Reelin signalling is hijacked to promote medulloblastoma metastasis (2023) (0)
- Reprogramming the microenvironment: tricks of tumor-derived astrocytes (2020) (0)
- STEM-17. THE GLIOMA STEM CELL PLATELET INTERACTION DRIVES GBM ONCOGENESIS IDENTIFYING A NOVEL THERAPEUTIC APPROACH (2021) (0)
- SC-22GLIOMA STEM CELLS INTERNALIZE BEVACIZUMAB FOUND IN THE PERIVASCULAR NICHE AND TARGET IT FOR RECYCLING OR DEGRADATION (2014) (0)
- Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy. (2022) (0)
- DRES-05. IDENTIFYING DRIVERS OF CHEMORESISTANCE IN GROUP 3 MEDULLOBLASTOMA THROUGH A GENOME-WIDE CRISPR/Cas9 ACTIVATION SCREEN (2017) (0)
- Signal transduction pathways as novel therapeutic targets in malignant glioma (2006) (0)
- Blood vessels in neurological development and disease: more than silent spectators (2010) (0)
- Abstract 5288: Glioma stem cells stimulate the motility of brain endothelial cells: Identification of cell-adhesion molecules mediating motility and direct interaction (2012) (0)
- News and Views Basic Science: Glioblastoma Stem Cells (2013) (0)
- Abstract IA13: The complexity of tumor cell hierarchies (2011) (0)
- LAB-METABOLIC PATHWAYS (2012) (0)
- STEM-36. A TRANSLATIONAL REPRESSION PROGRAM IS ASSOCIATED WITH THE STEM CELL STATE IN GLIOBLASTOMA (2017) (0)
- STEM-29. LAMINA ORGANIZATION PROMOTES MAINTENANCE OF BRAIN TUMOR INITIATING CELLS IN GLIOMA (2017) (0)
- Differential Connexin Func tion Enhances Self-Renewal in Glioblastoma Graphical (2015) (0)
- A Transcriptional State Driven by Yin Yang 1 Confers a Therapeutic Vulnerability in Glioblastoma Stem Cells (2020) (0)
- SCDT-23. VISUALIZATION OF BRAIN TUMOR BY NEAR-INFRARED FLUORESCENCE IMAGING VIA TUMOR-TARGETING NOVEL PEPTIDE IDENTIFIED BY PHAGE DISPLAY (2017) (0)
- N 6-methyladenine DNA Modification in Glioblastoma Graphical (2018) (0)
- STMC-38. EYA1 IDENTIFIED BY IN VITRO AND IN VIVO PHAGE DISPLAY BIOPANNING DEMONSTRATES ROLE IN GLIOBLASTOMA STEM CELL PROLIFERATION THROUGH ONCOGENE INTERACTION (2016) (0)
- PARP Inhibition Chemosensitizes Colorectal Cancer Stem Cells (2013) (0)
- Abstract 5192: Platelet derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity (2012) (0)
- IMST-39. IDO1 IS PROGNOSTIC FOR GLIOBLASTOMA PATIENT SURVIVAL AND CENTRALLY CORRELATES WITH POTENTLY IMMUNOSUPPRESSIVE MEDIATORS (2016) (0)
- STEM-13. IDENTIFICATION OF NOVEL TARGETS IN GLIOBLASTOMA STEM CELLS THROUGH CRISPR-Cas9 SCREENING (2017) (0)
- Abstract A47: Inhibition of histone methyltransferase with novel epipolythiodioxopiperazines (ETP) alkaloids in pediatric high-grade glioma (2018) (0)
- CBIO-15NON-METABOLIC FUNCTION OF PHOSPHOFRUCTOKINASE-1 IN GLIOBLASTOMA MAINTENANCE. (2015) (0)
- Abstract 3371: Targeting glioblastoma stem cell pathways through phage display screening (2012) (0)
- TAMI-59. METABOLIC REGULATION OF THE EPIGENOME DRIVES LETHAL INFANTILE EPENDYMOMA (2020) (0)
- Treatment Intensification for HPV-Unrelated Head and Neck Squamous Cell Carcinoma With Nab -Paclitaxel-Based Chemotherapy followed by Cisplatin and Radiation Therapy (2018) (0)
- EPEN-18. Oncogenic 3D genome conformations identify novel therapeutic targets in ependymoma (2020) (0)
- GENE-32. ACTIVE CHROMATIN REGULATORY MAPS IDENTIFY CORE CELL STATE DRIVERS OF GLIOBLASTOMA (2017) (0)
- Tumor and Stem Cell Biology Aptamer Identi fi cation of Brain Tumor – Initiating Cells (2013) (0)
- ET-36HYPERTHERMIA IMPROVES THE RADIOSENSITIVITY OF GLIOMA STEM CELLS BY INHIBITION OF AKT SIGNALING (2014) (0)
- P01.07 The Dystroglycan Complex Promotes Mesenchymal-Like Glioblastoma through Interaction with EphA Receptor Tyrosine Kinases (2017) (0)
- EXTH-75. IMAGING GLIOBLASTOMA STEM CELLS WITH 7-AMINO ACID-LENGTH TUMOR-HOMING PEPTIDE IDENTIFIED BY PHAGE DISPLAY BIOPANNING (2017) (0)
- MR-01MicroRNA-145 REGULATES JAM-A EXPRESSION AND COMPROMISES GLIOBLASTOMA MAINTENANCE (2014) (0)
- Radiation-induced IL-6 Secretion from Senescent Fibroblasts Increases Proliferation of Colorectal Cancer Stem Cells (2014) (0)
- STMC-30. TRAFFICKING AND EFFECT ON SURVIVAL OF BEVACIZUMAB IN GLIOBLASTOMA (2016) (0)
- Establishing a Colon Cancer Stem Cell Model to Study Tumor Chemoresistance (2012) (0)
- Abstract 5226: Glioma stem cells internalize perivascular bevacizumab via a non-canonical pathway and target it for recycling or degradation (2015) (0)
- STEM-24. CORE CLOCK GENES REGULATE CANCER STEM CELLS IN BRAIN TUMOR (2017) (0)
- ETMM-08 METABOLIC REGULATION OF THE EPIGENOME DRIVES LETHAL INFANTILE EPENDYMOMA (2021) (0)
- Editorial Board (2012) (0)
- SP-0002: Updates on stem cells and radioresistance (2014) (0)
- Reply to ‘Assembling the brain trust: the multidisciplinary imperative in neuro-oncology’ (2019) (0)
- STEM-21DISRUPTION OF FACILITATES CHROMATIN TRANSCRIPTION (FACT) SYNERGIZES WITH EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) INHIBITION AND PREFERENTIALLY TARGETS GLIOBLASTOMA STEM CELLS (2015) (0)
- STEM-22. TARGETING PYRIMIDINE SYNTHESIS ACCENTUATES MOLECULAR THERAPY RESPONSE IN GLIOBLASTOMA STEM CELLS (2019) (0)
- TMOD-34. DNA HELICASES HELB AND ATRX MAINTAIN GLIOMA STEM CELLS (2017) (0)
- STEM-12FATE OF BEVACIZUMAB IN GLIOBLASTOMA (2015) (0)
- STEM-08. PLATELETS DRIVES GLIOBLASTOMA ONCOGENESIS BY ENHANCING THE GLIOMA STEM CELL PHENOTYPE (2020) (0)
- STEM-10. BIDIRECTIONAL INTERACTION BETWEEN TUMOR-ASSOCIATED PLATELETS AND GLIOMA STEM CELLS IN GLIOBLASTOMA MULTIFORME (2019) (0)
- STEM-10. SUPER-ENHANCER SCREEN IDENTIFIES LIPID METABOLISM AS A CANCER STEM CELL DEPENDENCY IN GLIOBLASTOMA (2017) (0)
- Abstract 3318: Molecular targeting of brain tumor stem cells (2010) (0)
- EPEN-52. METABOLIC REGULATION OF THE EPIGENOME DRIVES LETHAL INFANTILE EPENDYMOMA (2020) (0)
- Abstract B68: miR-218 opposes an important RTK–HIF signaling pathway in Glioblastoma (2015) (0)
- FSMP-08. TARGETING PYRIMIDINE SYNTHESIS ACCENTUATES MOLECULAR THERAPY RESPONSE IN GLIOBLASTOMA STEM CELLS (2021) (0)
- HG-06INHIBITION OF EPIGENETIC REGULATION AS A THERAPY FOR PEDIATRIC HIGH GRADE GLIOMA (2015) (0)
- Treatment of adults with recurrent progressive low-grade glioma using imatinib mesylate and hydroxyurea (2008) (0)
- MOLECULAR MOTORS AS NOVEL TARGETS TO BLOCK GLIOMA DISPERSION AND PROLIFERATION. (2014) (0)
- IMMU-43. ZIKA VIRUS TO TREAT GLIOMA: TURNING COLD TUMORS HOT (2020) (0)
- DIRECT CELL CONTACT BETWEEN BRAIN ENDOTHELIAL CELLS AND GLIOMA STEM CELLS PROMOTES ENDOTHELIAL CELL MIGRATION (2014) (0)
- CS-21EphA2 PROMOTES INFILTRATIVE INVASION OF GLIOMA STEM CELLS IN VIVO THROUGH CROSSTALK WITH Akt AND REGULATES STEM PROPERTIES (2014) (0)
- STEM-43. GSK3β PROMOTES THE BMX-MEDIATED STAT3 ACTIVATION TO MAINTAIN GLIOBLASTOMA STEM CELLS (2017) (0)
- 3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma (2023) (0)
- TMIC-27. CONTACT-INDUCED BI-DIRECTIONAL PRO-SURVIVAL SIGNALING BETWEEN ENDOTHELIAL CELLS AND CANCER STEM-LIKE CELLS IN GLIOBLASTOMA (2016) (0)
- SC-11DIFFERENTIAL CONNEXIN FUNCTION ENHANCES SELF-RENEWAL IN GLIOBLASTOMA (2014) (0)
- Editorial Board (2009) (0)
- Abstract LB-65: Bevacizumab fate in glioblastoma: Mechanism of internalization by endothelial cells and glioma stem cells (2014) (0)
- Lending an ‘ELPing hand to tumor initiation (2015) (0)
- Phase I I T rial o f T emozolomide i n P atients W ith P rogressive Low-Grade G lioma (2003) (0)
- PO-340 Tumour heterogeneity in patient-derived glioblastoma organoids (2018) (0)
- Targeting Metabolic Reprogramming to Radiosensitize Glioblastoma Stem Cells (2019) (0)
- Hyperthermia Sensitizes Glioblastoma Stem Cells to Radiation (2012) (0)
- The Cancer Stem Cell Paradigm (2011) (0)
- Abstract A064: IDO1 expression stratifies glioblastoma patient survival and correlates with dominantly immunosuppressive pathways (2016) (0)
- Abstract 4044: Pharmacological targeting of the circadian clock, a new frontier for cancer therapy (2020) (0)
- TARGET IDENTIFICATION IN GLIOMA INITIATING CELLS. (2014) (0)
- STEM-14. THE WRAD COMPLEX REPRESENTS A THERAPEUTIC TARGET FOR CANCER STEM CELLS IN GLIOBLASTOMA (2021) (0)
- EPND-01. THE ACTIVE REGULATORY LANDSCAPE OF EPENDYMAL TUMORS. (2017) (0)
- Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression. (2012) (0)
- TAMI-18. DIFFERENTIAL LIPID METABOLISM IN CANCER MICROENVIRONMENTS LEADS TO A REQUIREMENT FOR FATTY ACID DESATURASES FADS1 AND FADS2 IN GBM CANCER STEM CELL MAINTENANCE (2021) (0)
- PDTM-23. THE ACTIVE REGULATORY LANDSCAPE OF EPENDYMAL TUMORS (2017) (0)
- LAB-STEM CELLS (2012) (0)
- Imatinib mesylate (STI-571, Gleevec®) offers combinatorial benefit with temozolomide (Temodar®) against gliomas (2005) (0)
- Abstract 6611: Functional characterization of a novel gene in the antigen presentation pathway allows specific immunotherapeutic targeting of glioblastoma cancer stem cells (2020) (0)
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What Schools Are Affiliated With Jeremy N Rich?
Jeremy N Rich is affiliated with the following schools:
