Jérôme Pugin
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Philosophy
Jérôme Pugin's Degrees
- Doctorate Medicine University of Geneva
- PhD Medical Sciences University of Geneva
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(Suggest an Edit or Addition)Jérôme Pugin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Diagnosis of ventilator-associated pneumonia by bacteriologic analysis of bronchoscopic and nonbronchoscopic "blind" bronchoalveolar lavage fluid. (1991) (1001)
- Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. (2001) (884)
- Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. (1993) (876)
- Protection from septic shock by neutralization of macrophage migration inhibitory factor (2000) (787)
- CD14 is a pattern recognition receptor. (1994) (767)
- Inappropriate initial antimicrobial therapy and its effect on survival in a clinical trial of immunomodulating therapy for severe sepsis. (2003) (646)
- Cytokine-mediated inflammation in acute lung injury. (2003) (621)
- Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial. (2008) (565)
- Cytokine balance in the lungs of patients with acute respiratory distress syndrome. (2001) (548)
- Normal responses to injury prevent systemic inflammation and can be immunosuppressive. (2001) (526)
- The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. (1999) (446)
- Clinical characteristics and day-90 outcomes of 4244 critically ill adults with COVID-19: a prospective cohort study (2020) (422)
- Adding a dialysis dose to continuous hemofiltration increases survival in patients with acute renal failure. (2006) (397)
- Activation of human macrophages by mechanical ventilation in vitro. (1998) (369)
- Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1. (1996) (341)
- Balance between proinflammatory cytokines and their inhibitors in bronchial lavage from patients with status asthmaticus. (1999) (261)
- Local inflammatory responses following bronchial endotoxin instillation in humans. (2001) (238)
- Human neutrophils secrete gelatinase B in vitro and in vivo in response to endotoxin and proinflammatory mediators. (1999) (235)
- Endocan, a new endothelial marker in human sepsis* (2006) (224)
- Oropharyngeal Decontamination Decreases Incidence of Ventilator-Associated Pneumonia: A Randomized, Placebo-Controlled, Double-blind Clinical Trial (1991) (217)
- Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide. (1998) (216)
- Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human Diseases (2018) (214)
- Contribution of Toll-like receptors to the innate immune response to Gram-negative and Gram-positive bacteria. (2007) (212)
- Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study (2006) (211)
- Role of interleukin-10 in the intracellular sequestration of human leukocyte antigen-DR in monocytes during septic shock. (2002) (194)
- Innate Immune Functions of Immature Neutrophils in Patients With Sepsis and Severe Systemic Inflammatory Response Syndrome* (2013) (192)
- β-Adrenergic agonists exert their “anti-inflammatory” effects in monocytic cells through the IκB/NF-κB pathway (2000) (188)
- Pulmonary edema fluid from patients with acute lung injury augments in vitro alveolar epithelial repair by an IL-1beta-dependent mechanism. (2001) (175)
- A critical role for monocytes and CD14 in endotoxin-induced endothelial cell activation (1993) (159)
- Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort (2020) (157)
- Oropharyngeal decontamination decreases incidence of ventilator-associated pneumonia. A randomized, placebo-controlled, double-blind clinical trial. (1991) (153)
- Combination of steroids with infliximab or placebo in severe alcoholic hepatitis: a randomized controlled pilot study. (2002) (152)
- Validation of a commercially available SARS-CoV-2 serological immunoassay (2020) (150)
- Augmented renal clearance, low β-lactam concentrations and clinical outcomes in the critically ill: an observational prospective cohort study. (2015) (148)
- Role of MAP kinase activation in interleukin-8 production by human BEAS-2B bronchial epithelial cells submitted to cyclic stretch. (2002) (146)
- Participation of lipopolysaccharide-binding protein in lipopolysaccharide-dependent macrophage activation. (1992) (143)
- Phagocytosis of Gram‐negative bacteria by a unique CD14‐dependent mechanism (1997) (134)
- Pulmonary Edema Fluid from Patients with Early Lung Injury Stimulates Fibroblast Proliferation through IL-1β-Induced IL-6 Expression 1 (2004) (133)
- CD14-dependent Endotoxin Internalization via a Macropinocytic Pathway* (1998) (131)
- Hospital-acquired pneumonia in ICU. (2017) (121)
- Compartmentalization of the inflammatory response during acute pancreatitis: correlation with local and systemic complications. (2003) (117)
- Molecular mechanisms of lung cell activation induced by cyclic stretch (2003) (111)
- Lipopolysaccharide (LPS)-binding protein and soluble CD14 function as accessory molecules for LPS-induced changes in endothelial barrier function, in vitro. (1994) (107)
- The Role of the Macrophage (2007) (100)
- Cell Activation Mediated by Glycosylphosphatidylinositol-Anchored or Transmembrane Forms of CD14 (1998) (100)
- Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock. (2004) (95)
- Role of biomarkers in the management of antibiotic therapy: an expert panel review: I – currently available biomarkers for clinical use in acute infections (2013) (93)
- Mechanical Ventilation Affects Lung Function and Cytokine Production in an Experimental Model of Endotoxemia (2005) (90)
- CC chemokines and interleukin-5 in bronchial lavage fluid from patients with status asthmaticus. Potential implication in eosinophil recruitment. (2000) (86)
- Efficacy and safety of citrate-based anticoagulation compared to heparin in patients with acute kidney injury requiring continuous renal replacement therapy: a randomized controlled trial (2015) (86)
- Rapid changes in alcoholic hepatitis histology under steroids: correlation with soluble intercellular adhesion molecule-1 in hepatic venous blood. (2001) (81)
- How tissue injury alarms the immune system and causes a systemic inflammatory response syndrome (2012) (80)
- beta-adrenergic agonists exert their "anti-inflammatory" effects in monocytic cells through the IkappaB/NF-kappaB pathway. (2000) (78)
- Innate Immune Deficiency of Extremely Premature Neonates Can Be Reversed by Interferon-γ (2012) (76)
- Long-term prognosis after acute kidney injury requiring renal replacement therapy. (2009) (74)
- Conventional mechanical ventilation of healthy lungs induced pro-inflammatory cytokine gene transcription (2002) (68)
- Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia (2004) (62)
- Soluble MD-2 is an acute-phase protein and an opsonin for Gram-negative bacteria. (2008) (61)
- Role of biomarkers in the management of antibiotic therapy: an expert panel review II: clinical use of biomarkers for initiation or discontinuation of antibiotic therapy (2013) (60)
- The 2014–2015 Ebola outbreak in West Africa: Hands On (2016) (59)
- Procalcitonin is not an accurate marker of spontaneous bacterial peritonitis in patients with cirrhosis. (2001) (57)
- Characteristics of an ideal nebulized antibiotic for the treatment of pneumonia in the intubated patient (2016) (56)
- Immunostimulation is a rational therapeutic strategy in sepsis. (2007) (55)
- Clinical signs and scores for the diagnosis of ventilator-associated pneumonia. (2002) (54)
- The lectin‐like domain of tumor necrosis factor‐α increases membrane conductance in microvascular endothelial cells and peritoneal macrophages (1999) (54)
- COVID-19–related encephalopathy responsive to high-dose glucocorticoids (2020) (53)
- Pivotal Involvement of Fcγ Receptor IIA in the Neutralization of Lipopolysaccharide Signaling via a Potent Novel Anti-TLR4 Monoclonal Antibody 15C1* (2007) (52)
- Cyclic stretch of human lung cells induces an acidification and promotes bacterial growth. (2008) (52)
- Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality (2020) (52)
- Extreme elevations of serum lactic dehydrogenase differentiating pulmonary toxoplasmosis from Pneumocystis pneumonia. (1992) (51)
- Clinical features and viral kinetics in a rapidly cured patient with Ebola virus disease: a case report. (2015) (51)
- Coronavirus Disease 2019 (COVID-19): A critical care perspective beyond China (2020) (49)
- Lack of effect of combination antibiotic therapy on mortality in patients with pneumococcal sepsis (2005) (49)
- Streptococcal toxic shock syndrome in the intensive care unit (2018) (48)
- Activation of endothelial cells by endotoxin: direct versus indirect pathways and the role of CD14. (1995) (47)
- Oropharyngeal Decontamination Decreases Incidence of Ventilator-Associated Pneumonia. A Randomized, Placebo-Controlled, Double-Blind Clinical Trial (1992) (45)
- Increased FGF21 plasma levels in humans with sepsis and SIRS (2013) (45)
- Rapid diagnosis of gram negative pneumonia by assay of endotoxin in bronchoalveolar lavage fluid. (1992) (45)
- Tumor necrosis factor-alpha and interleukin-1 beta mediate human endothelial cell activation in blood at low endotoxin concentrations. (1995) (44)
- Is Dressler syndrome dead? (2004) (44)
- Mechanical ventilation of various human lung cells in vitro: identification of the macrophage as the main producer of inflammatory mediators. (1999) (43)
- Epoetin administrated after cardiac surgery: effects on renal function and inflammation in a randomized controlled study (2012) (43)
- Immune monitoring of patients with septic shock by measurement of intraleukocyte cytokines (2004) (40)
- Mild-stretch mechanical ventilation upregulates toll-like receptor 2 and sensitizes the lung to bacterial lipopeptide (2011) (39)
- First case of Candida auris in Switzerland: discussion about preventive strategies. (2018) (39)
- Year in review in intensive care medicine, 2005. II. Infection and sepsis, ventilator-associated pneumonia, ethics, haematology and haemostasis, ICU organisation and scoring, brain injury (2006) (39)
- Identification of respiratory microbiota markers in ventilator-associated pneumonia (2019) (37)
- Mental health outcomes of ICU and non-ICU healthcare workers during the COVID-19 outbreak: a cross-sectional study (2021) (36)
- Diagnostic bronchoalveolar lavage in patients with pneumonia produces sepsis-like systemic effects (2005) (35)
- Year in review in intensive care medicine, 2004. I. Respiratory failure, infection, and sepsis (2004) (35)
- French Intensive Care Society, International congress – Réanimation 2016 (2016) (33)
- Year in review in Intensive Care Medicine 2009: I. Pneumonia and infections, sepsis, outcome, acute renal failure and acid base, nutrition and glycaemic control (2010) (32)
- The crucial role of systemic responses in the innate (non-adaptive) host defense (2001) (31)
- Year in review in intensive care medicine, 2004. III. Outcome, ICU organisation, scoring, quality of life, ethics, psychological problems and communication in the ICU, immunity and hemodynamics during sepsis, pediatric and neonatal critical care, experimental studies (2005) (30)
- Implications of early respiratory support strategies on disease progression in critical COVID-19: a matched subanalysis of the prospective RISC-19-ICU cohort (2021) (30)
- Can calculation of energy expenditure based on CO2 measurements replace indirect calorimetry? (2017) (29)
- Year in review in Intensive Care Medicine 2010: III. ARDS and ALI, mechanical ventilation, noninvasive ventilation, weaning, endotracheal intubation, lung ultrasound and paediatrics (2011) (29)
- Is the ventilator responsible for lung and systemic inflammation ? (2002) (29)
- A first update on mapping the human genetic architecture of COVID-19 (2022) (27)
- Membrane interaction of TNF is not sufficient to trigger increase in membrane conductance in mammalian cells (1999) (27)
- Selective Antibody Intervention of Toll-like Receptor 4 Activation through Fc γ Receptor Tethering (2014) (27)
- Efficacy and safety of suvratoxumab for prevention of Staphylococcus aureus ventilator-associated pneumonia (SAATELLITE): a multicentre, randomised, double-blind, placebo-controlled, parallel-group, phase 2 pilot trial. (2021) (27)
- Prompt antibiotic administration and goal-directed hemodynamic support in patients with severe sepsis and septic shock (2007) (27)
- Is the measurement of monocytes HLA-DR expression useful in patients with sepsis? (2006) (27)
- Challenges in the culture-independent analysis of oral and respiratory samples from intubated patients (2014) (27)
- Preparedness and Reorganization of Care for Coronavirus Disease 2019 Patients in a Swiss ICU: Characteristics and Outcomes of 129 Patients (2020) (26)
- Impact of a multifaceted prevention program on ventilator-associated pneumonia including selective oropharyngeal decontamination (2018) (26)
- Influenza-associated aspergillosis in critically-ill patients—a retrospective bicentric cohort study (2020) (25)
- Ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: understanding nebulization of aminoglycosides and colistin (2020) (25)
- Increased release of sMD-2 during human endotoxemia and sepsis: a role for endothelial cells. (2008) (25)
- COVID‐19 encephalopathy: Clinical and neurobiological features (2021) (25)
- Characteristics, management, and prognosis of elderly patients with COVID-19 admitted in the ICU during the first wave: insights from the COVID-ICU study (2021) (24)
- Biomarkers of sepsis: is procalcitonin ready for prime time? (2002) (24)
- Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis* (2021) (23)
- Brief summary of French guidelines for the prevention, diagnosis and treatment of hospital-acquired pneumonia in ICU (2018) (23)
- Influence of positive end-expiratory pressure (PEEP) on histopathological and bacteriological aspects of pneumonia during low tidal volume mechanical ventilation (2004) (22)
- Long COVID neuropsychological deficits after severe, moderate or mild infection (2021) (22)
- Granulocyte colony‐stimulating factor (G‐CSF) downregulates its receptor (CD114) on neutrophils and induces gelatinase B release in humans (2000) (21)
- Role of proinflammatory activity contained in gastric juice from intensive care unit patients to induce lung injury in a rabbit aspiration model (2008) (21)
- Burden of illness imposed by severe sepsis in Switzerland. (2004) (20)
- Year in review in intensive care medicine. 2005. I. Acute respiratory failure and acute lung injury, ventilation, hemodynamics, education, renal failure (2006) (20)
- Dear SIRS, the concept of “alarmins” makes a lot of sense! (2008) (20)
- Year in review in Intensive Care Medicine, 2006. II. Infections and sepsis, haemodynamics, elderly, invasive and noninvasive mechanical ventilation, weaning, ARDS (2007) (19)
- Year in review in Intensive Care Medicine, 2008: II. Experimental, acute respiratory failure and ARDS, mechanical ventilation and endotracheal intubation (2009) (19)
- [ The intestine-liver-lung axis in septic syndrome]. (1991) (19)
- Benefits and risks of noninvasive oxygenation strategy in COVID-19: a multicenter, prospective cohort study (COVID-ICU) in 137 hospitals (2021) (18)
- Mitochondrial alarmins are tissue mediators of ventilator-induced lung injury and ARDS (2019) (16)
- Evolving Concepts in Sepsis and Septic Shock (2001) (16)
- Year in review in Intensive Care Medicine, 2008: I. Brain injury and neurology, renal failure and endocrinology, metabolism and nutrition, sepsis, infections and pneumonia (2008) (16)
- Year in review in Intensive Care Medicine 2009. Part III: Mechanical ventilation, acute lung injury and respiratory distress syndrome, pediatrics, ethics, and miscellanea (2010) (16)
- Toll-like Receptor Activation of Human Cells by Synthetic Triacylated Lipid A-like Molecules* (2012) (16)
- A high-risk gut microbiota configuration associates with fatal hyperinflammatory immune and metabolic responses to SARS-CoV-2 (2022) (15)
- Serial measurement of pancreatic stone protein for the early detection of sepsis in intensive care unit patients: a prospective multicentric study (2021) (15)
- Measured and Estimated Glomerular Filtration Rate in the ICU: A Prospective Study. (2020) (14)
- Easy-to-prescribe nutrition support in the intensive care in the era of COVID-19 (2020) (14)
- mRNA-based SARS-CoV-2 vaccination is associated with reduced ICU admission rate and disease severity in critically ill COVID-19 patients treated in Switzerland (2022) (13)
- Cooperation between PU.1 and CAAT/Enhancer-binding Protein β Is Necessary to Induce the Expression of the MD-2 Gene* (2009) (13)
- Acute portal hemodynamics and cytokine changesfollowing selective transarterial chemoembolization in patients with cirrhosis and hepatocellular carcinoma. (2003) (13)
- Therapeutic anticoagulation to prevent thrombosis, coagulopathy, and mortality in severe COVID‐19: The Swiss COVID‐HEP randomized clinical trial (2022) (12)
- Adrenomedullin: a vasodilator to treat sepsis? (2014) (12)
- Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration (2011) (12)
- The role of MD-2 in the opsonophagocytosis of Gram-negative bacteria (2009) (12)
- Soluble MD2 is an acute phase protein and an opsonin for Gram-negative bacteria (2007) (12)
- Mechanical Ventilation Alters the Development of Staphylococcus aureus Pneumonia in Rabbit (2016) (11)
- LPS binding protein and CD14 in the LPS dependent activation of cells. (1994) (11)
- Interstitial, Inflammatory and Occupational Lung Disease: Ventilator‐Induced Lung Injury An Inflammatory Disease? (1998) (11)
- Management and outcomes of pregnant women admitted to intensive care unit for severe pneumonia related to SARS-CoV-2 infection: the multicenter and international COVIDPREG study (2022) (11)
- Characteristics and prognosis of bloodstream infection in patients with COVID-19 admitted in the ICU: an ancillary study of the COVID-ICU study (2021) (11)
- Year in review in intensive care medicine, 2005. III. Nutrition, pediatric and neonatal critical care, and experimental (2006) (11)
- The impact of mechanical ventilation on the moxifloxacin treatment of experimental pneumonia caused by Streptococcus pneumoniae (2005) (11)
- The search for diagnostic markers in sepsis: many miles yet to go. (2012) (11)
- Year in review in Intensive Care Medicine, 2007. III. Ethics and legislation, health services research, pharmacology and toxicology, nutrition and paediatrics (2008) (10)
- Activation of human macrophages by mechanical ventilation in vitro. (1998) (9)
- Recognition of Bacteria and Bacterial Products by Host Immune Cells in Sepsis (1996) (9)
- Hemodynamics in experimental gastric juice induced aspiration pneumonitis (2007) (9)
- Functional connectivity underlying cognitive and psychiatric symptoms in post-COVID-19 syndrome: is anosognosia a key determinant? (2022) (9)
- Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease (2022) (9)
- The IASIS, INHALE and VAPORISE trials. Reasons for a triple failure: study design, aminoglycosides dosing and technique of nebulisation. (2020) (9)
- Extremely high-dose insulin requirement in a diabetic patient with COVID-19: a case report (2020) (9)
- Granulocyte colony-stimulating factor (G-CSF) downregulates its receptor (CD114) on neutrophils and induces gelatinase B release in humans. (2000) (9)
- Year in Review in Intensive Care Medicine, 2006. III. Circulation, ethics, cancer, outcome, education, nutrition, and pediatric and neonatal critical care (2007) (8)
- Year in review in Intensive Care Medicine 2010: II. Pneumonia and infections, cardiovascular and haemodynamics, organization, education, haematology, nutrition, ethics and miscellanea (2011) (8)
- Early Measurement of ROX Index in Intermediary Care Unit Is Associated with Mortality in Intubated COVID-19 Patients: A Retrospective Study (2022) (8)
- Year in review in Intensive Care Medicine 2010: I. Acute renal failure, outcome, risk assessment and ICU performance, sepsis, neuro intensive care and experimentals (2011) (8)
- b -Adrenergic agonists exert their “anti-inflammatory” effects in monocytic cells through the I k B/NF- k B pathway (2000) (8)
- Sepsis and the immune response (1999) (8)
- Mechanisms of Cellular Activation by Endotoxin1 (1995) (8)
- Year in review in intensive care medicine, 2004. II. Brain injury, hemodynamic monitoring and treatment, pulmonary embolism, gastrointestinal tract, and renal failure (2005) (8)
- Year in review in Intensive Care Medicine, 2008: III. Paediatrics, Ethics, outcome research and critical care organization, sedation, pharmacology and miscellanea (2009) (7)
- Impact of nutritional therapy during the first wave of the COVID-19 pandemic in intensive care patients: A retrospective observational study (2021) (7)
- Year in review in Intensive Care Medicine 2009: II. Neurology, cardiovascular, experimental, pharmacology and sedation, communication and teaching (2010) (7)
- Year in review in Intensive Care Medicine, 2006. I. Experimental studies. Clinical studies: brain injury, renal failure and endocrinology (2006) (7)
- Predicting 90-day survival of patients with COVID-19: Survival of Severely Ill COVID (SOSIC) scores (2021) (7)
- Suvratoxumab Reduces Staphylococcus Aureus Pneumonia in High-Risk ICU Patients: Results of the SAATELLITE Study (2019) (7)
- [Usefulness of procalcitonin in adults and children]. (2005) (7)
- Delayed intubation is associated with mortality in patients with severe COVID-19: A single-centre observational study in Switzerland (2022) (6)
- Mechanical ventilation and Streptococcus pneumoniae pneumonia alter mitochondrial homeostasis (2018) (6)
- Dynamics of disease characteristics and clinical management of critically ill COVID-19 patients over the time course of the pandemic: an analysis of the prospective, international, multicentre RISC-19-ICU registry (2022) (6)
- Clinical Metagenomics for the Diagnosis of Hospital-acquired Infections: Promises and Hurdles. (2017) (6)
- Frequency of Abnormally Low Neuropsychological Scores in Post-COVID-19 Syndrome: the Geneva COVID-COG Cohort (2022) (5)
- RADICAL study: rapid diagnosis of suspected bloodstream infections from direct blood testing using PCR/ESI-MS (2014) (5)
- Bacteremia, sepsis and shock (2005) (4)
- Early prone positioning in acute respiratory distress syndrome related to COVID-19: a propensity score analysis from the multicentric cohort COVID-ICU network—the ProneCOVID study (2022) (4)
- Early prone positioning in acute respiratory distress syndrome related to COVID-19: a propensity score analysis from the multicentric cohort COVID-ICU network—the ProneCOVID study (2022) (4)
- Pseudomembranous colitis: an unusual cause of neutrocytic ascites. (1999) (4)
- Hypophosphatemia on ICU Admission Is Associated with an Increased Length of Stay in the ICU and Time under Mechanical Ventilation (2022) (4)
- SARS‐CoV‐2 infection as a trigger of humoral response against apolipoprotein A‐1 (2021) (4)
- Brain functional connectivity alterations associated with neuropsychological performance 6–9 months following SARS‐CoV‐2 infection (2022) (4)
- 2839. Efficacy, Pharmacokinetics (PK), and Safety Profile of Suvratoxumab (MEDI4893), a Staphylococcus aureus Alpha Toxin (AT)-Neutralizing Human Monoclonal Antibody in Mechanically Ventilated Patients in Intensive Care Units; Results of the Phase 2 SAATELLITE Study Conducted by the Public-Private C (2019) (4)
- Single cell profiling in COVID-19 associated acute kidney injury reveals patterns of tubule injury and repair in human (2021) (3)
- Profiling genes in the ICU: Are we there yet? (2008) (3)
- Kinetic GFR Outperforms CKD-EPI for Slow Graft Function Prediction in the Immediate Postoperative Period Following Kidney Transplantation (2020) (3)
- Is anti-tumor necrosis factor therapy associated with increased mortality in patients with severe sepsis caused by pneumonia? (2004) (3)
- Decreased CRRT Filter Lifespan in COVID-19 ICU Patients (2021) (3)
- SARS-COV2- infection as a trigger of humoral response against apolipoprotein A-1 (2021) (3)
- Preparedness and Reorganization of Care for COVID-19 Patients in a Swiss Intensive Care Unit: Characteristics and Outcomes of the First 120 Patients (2020) (2)
- Year in review in Intensive Care Medicine, 2007. I. Experimental studies. Clinical studies: brain injury and neurology, renal failure and endocrinology (2008) (2)
- Nebulized antibiotics for ventilator-associated pneumonia: methodological framework for future multicenter randomized controlled trials (2021) (2)
- ESICM LIVES 2016: part two (2016) (2)
- Healthcare associated pneumonia in the intensive care unit (2018) (2)
- SPHN/PHRT: Forming a Swiss-Wide Infrastructure for Data-Driven Sepsis Research (2020) (2)
- Erratum to: Can calculation of energy expenditure based on CO2 measurements replace indirect calorimetry? (2017) (2)
- Retinal Manifestations in Patients with COVID-19: A Prospective Cohort Study (2022) (2)
- A COVID-19-Related Retinopathy Case Report (2022) (2)
- How Can We Help Healthcare Workers during a Catastrophic Event Such as the COVID-19 Pandemic? (2022) (2)
- [The diagnosis of pneumonia in the ventilated patient]. (1990) (2)
- 2160. Performance of the Cepheid Rapid PCR Test for Patient Screening and Association with Efficacy of Suvratoxumab, A Novel Anti-Staphylococcus aureus Monoclonal Antibody, During the Phase 2 SAATELLITE study (2019) (2)
- Early Prone Positioning in Acute Respiratory Distress Syndrome Related to COVID-19: A Propensity Score Analysis from the Multicentric Cohort COVID-ICU network. The ProneCOVID Study. (2021) (2)
- Toll-Like Receptors (2001) (1)
- 2142. Comparison of Molecular-Based vs. Conventional Culture-Based Screening Methods for Detection of Carriers of Extended-Spectrum β-Lactamases (ESBL) and Carbapenemases-Producing Enterobacteriacae (CPE) (2019) (1)
- Traitement du choc septique par épuration extracorporelle de l’endotoxine circulante (2013) (1)
- Year in Review 2007 (1)
- Correction to: Ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: understanding nebulization of aminoglycosides and colistin (2020) (1)
- Use of high-volume haemodiafiltration in patients with refractory septic shock and acute kidney injury (2012) (1)
- Excessive inflammatory and metabolic responses to acute SARS-CoV-2 infection are associated with a distinct gut microbiota composition (2021) (1)
- Impaired renal gluconeogenesis is a major determinant of acute kidney injury associated mortality (2019) (1)
- Year in Review 2007 (1)
- Limitation of life-sustaining therapies in critically ill patients with COVID-19: a descriptive epidemiological investigation from the COVID-ICU study (2023) (0)
- Author Correction: Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality (2020) (0)
- ORAL DECONTAMINATION AND VENTILATOR-ASSOCIATED PNEUMONIA. AUTHORS' REPLY (1991) (0)
- [Ebola: between anxiety and reason]. (2014) (0)
- Bacterial contamination of the hands of intensive care unit staff during respiratory tract care: preliminary results (2015) (0)
- Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality (2020) (0)
- [Palliative and intensive care collaborative approach in the management of therapeutic withdrawals: lessons learned from the COVID-19 experience]. (2020) (0)
- Correction to: Characteristics and prognosis of bloodstream infection in patients with COVID‑19 admitted in the ICU: an ancillary study of the COVID‑ICU study (2022) (0)
- Mechanical Stretch Causes Mitochondrial Dysfunction and the Release of Mitochondrial DAMPs in Alveolar Epithelial Cells (2019) (0)
- Bacterial contamination of the hands of intensive care unit staff during respiratory tract care: preliminary results (2015) (0)
- Mechanical ventilation and Streptococcus pneumoniae pneumonia alter mitochondrial homeostasis (2018) (0)
- A Radical Approach To Diagnosing Infection (2015) (0)
- Free Papers (2016) (0)
- Human endothelial cell responses to endotoxin are dramatically enhanced by human blood (1994) (0)
- Gram-negative and Gram-positive bacteria Contribution of Toll-like receptors to the innate immune response to (2013) (0)
- Protein Intake In Intensive Care Patients With Covid-19 – Comparison Before And After Optimization Of A Simplified Nutrition Protocol. (2023) (0)
- [Sepsis : particularities in the elderly patients]. (2016) (0)
- Growth Arrest-Specific Gene 6 product modulates innate immunity in sepsis (2008) (0)
- Downregulation of CD14 and toll-like receptors during human dendritic cell differentiation and maturation in vitro (2000) (0)
- ' s response to reviews Title : Epoetin administrated after cardiac surgery : effects on renal function and inflammation in a randomized controlled study (2012) (0)
- Acute renal failure - clinical studies - 2 (2009) (0)
- ANTIMICROBIAL ACTIVITY OF LOCAL ANAESTHETICS. REPLY (1992) (0)
- Expression-Induced IL-6 β Proliferation through IL-1 Early Lung Injury Stimulates Fibroblast Pulmonary Edema Fluid from Patients with Pugin and (2004) (0)
- P125: Promoting hand hygiene in intensive care: a permanent challenge (2013) (0)
- Distinct from That Used by Lipopolysaccharide Monocytic Cells via a CD 14-Dependent Pathway Lipoproteins and Synthetic Lipopeptides Activate Borrelia burgdorferi and Treponema pallidum (1998) (0)
- P125: Promoting hand hygiene in intensive care: a permanent challenge (2013) (0)
- [Why a post-intensive care consultation ?] (2018) (0)
- shock Soluble MD-2 activity in plasma from patients with severe sepsis and septic (2013) (0)
- Negative-pressure helmet restores cerebral hemodynamic parameters in sinking skin flap syndrome: a case report (2022) (0)
- Gram-negative bacteria Soluble MD-2 is an acute-phase protein and an opsonin for (2008) (0)
- Toll-like Receptor Activation of Human Cells by Synthetic (2012) (0)
- Acute TNFα levels predict cognitive impairment 6–9 months after COVID-19 infection (2023) (0)
- 005 Endocan, a potential new endothelial marker in human sepsis (2005) (0)
- 1557. Population Pharmacokinetics of Suvratoxumab (MEDI4893), an Extended Half-life Staphylococcus aureus Alpha Toxin-Neutralizing Human Monoclonal Antibody, in Healthy Adults and Patients on Mechanical Ventilation in Intensive Care Units (2019) (0)
- Oral Decontamination and Ventilator-Associated Pneumonia-Reply (1991) (0)
- An interventional quasi-experimental study to evaluate the impact of a rapid screening strategy in improving control of nosocomial extended-spectrum beta-lactamase-producing Enterobacterales and carbapenemase-producing organisms in critically ill patients (2022) (0)
- The 2014–2015 Ebola outbreak in West Africa: Hands On (2016) (0)
- Promoting hand hygiene in intensive care: “PCI Licence” (2015) (0)
- Role of Growth Arrest-Specific Gene 6 Product (Gas6) in Severe Sepsis. (2006) (0)
- Nonventilatory Management of ARDS (1989) (0)
- [Treatment of septic shock by removing blood endotoxin]. (2013) (0)
- Promoting hand hygiene in intensive care: “PCI Licence” (2015) (0)
- Massive Hemoptysis and Dyspnea in an 18-Year-Old Woman. (2021) (0)
- Author Correction: Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality (2020) (0)
- TNF-peptides for the treatment of edema (1999) (0)
- Effect of therapeutic anticoagulation on gas exchange in mechanically ventilated COVID-19 patients: A secondary analysis of the COVID-HEP trial (2023) (0)
- Use of antibodies for prevention of impacts caused by grampositive- and myco-bacteria (1995) (0)
- Performance of the Cepheid Methicillin-Resistant Staphylococcus aureus/S. aureus Skin and Soft Tissue Infection PCR Assay on Respiratory Samples from Mechanically Ventilated Patients for S. aureus Screening during the Phase 2 Double-Blind SAATELLITE Study (2022) (0)
- Growth Cyclic Stretch of Human Lung Cells Induces an Acidification (2002) (0)
- Intracerebral hemorrhage in ICU: is it worth treating? (2016) (0)
- Free Papers (2011) (0)
- Influenza-associated aspergillosis in critically-ill patients—a retrospective bicentric cohort study (2020) (0)
- TNF-peptides and their use for the treatment of edema (1999) (0)
- Unsupervised clustering reveals phenotypes of AKI in ICU COVID-19 patients (2022) (0)
- TNF-derived peptides for use in the treatment of edema. (1999) (0)
- Human Herpesvirus 6 Reactivation: A Rare Case of Acute Liver Failure and Literature Review (2023) (0)
- Molecules Cells by Synthetic Triacylated Lipid A-like Toll-like Receptor Activation of Human Immunology: (2014) (0)
- Limitation of life-sustaining therapies in critically ill patients with COVID-19: a descriptive epidemiological investigation from the COVID-ICU study (2023) (0)
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What Schools Are Affiliated With Jérôme Pugin?
Jérôme Pugin is affiliated with the following schools: