Jerry J. Buccafusco
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Philosophy Biology
Jerry J. Buccafusco's Degrees
- PhD Neuroscience University of California, Irvine
- Doctorate Medicine University of California, Irvine
Why Is Jerry J. Buccafusco Influential?
(Suggest an Edit or Addition)Jerry J. Buccafusco's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Cholinergic Hypothesis of Age and Alzheimer's Disease-Related Cognitive Deficits: Recent Challenges and Their Implications for Novel Drug Development (2003) (973)
- Guidelines on nicotine dose selection for in vivo research (2007) (747)
- Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder (2006) (514)
- Methods of Behavior Analysis in Neuroscience (2000) (449)
- Multi-functional drugs for various CNS targets in the treatment of neurodegenerative disorders. (2005) (360)
- m1–m5 Muscarinic Receptor Distribution in Rat CNS by RT‐PCR and HPLC (1994) (201)
- Broad-Spectrum Efficacy across Cognitive Domains by α7 Nicotinic Acetylcholine Receptor Agonism Correlates with Activation of ERK1/2 and CREB Phosphorylation Pathways (2007) (195)
- Functional Characterization of the Novel Neuronal Nicotinic Acetylcholine Receptor Ligand GTS-21 In Vitro and In Vivo (1997) (189)
- Beneficial effects of nicotine administered prior to a delayed matching-to-sample task in young and aged monkeys (1991) (156)
- Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance. (2005) (151)
- Pharmacological study of a cholinergic mechanism within the rat posterior hypothalamic nucleus which mediates a hypertensive response (1979) (144)
- Desensitization of Nicotinic Acetylcholine Receptors as a Strategy for Drug Development (2009) (138)
- Nicotine enhances delayed matching-to-sample performance by primates. (1988) (138)
- Lecozotan (SRA-333): A Selective Serotonin 1A Receptor Antagonist That Enhances the Stimulated Release of Glutamate and Acetylcholine in the Hippocampus and Possesses Cognitive-Enhancing Properties (2005) (125)
- CNS Targets for multi-functional drugs in the treatment of Alzheimer’s and Parkinson’s diseases (2005) (123)
- Relationship between the increased cell surface α7 nicotinic receptor expression and neuroprotection induced by several nicotinic receptor agonists (2001) (123)
- Autoimmunity in Alzheimer’s disease: increased levels of circulating IgGs binding Aβ and RAGE peptides (2004) (122)
- The role of central cholinergic neurons in the regulation of blood pressure and in experimental hypertension. (1996) (114)
- Repeated Exposures to Subthreshold Doses of Chlorpyrifos in Rats: Hippocampal Damage, Impaired Axonal Transport, and Deficits in Spatial Learning (2003) (112)
- Cognitive dysfunction in neuropsychiatric disorders: Selected serotonin receptor subtypes as therapeutic targets (2008) (111)
- Multiple central nervous system targets for eliciting beneficial effects on memory and cognition. (2000) (110)
- In Vivo Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107: Preclinical Considerations in Alzheimer's Disease (2010) (107)
- Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. Part II (1997) (106)
- An evaluation of the mechanism of scopolamine-induced impairment in two passive avoidance protocols (1988) (102)
- Symposium overview: the use of delayed matching-to-sample procedures in studies of short-term memory in animals and humans. (1998) (99)
- Central nicotinic receptor agonists ABT-418, ABT-089, and (–)-nicotine reduce distractibility in adult monkeys (1998) (95)
- Chronic, Intermittent Exposure to Chlorpyrifos in Rats: Protracted Effects on Axonal Transport, Neurotrophin Receptors, Cholinergic Markers, and Information Processing (2007) (88)
- ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys. (1997) (87)
- A reversible model of the cognitive impairment associated with schizophrenia in monkeys: potential therapeutic effects of two nicotinic acetylcholine receptor agonists. (2009) (79)
- Microtubule-associated targets in chlorpyrifos oxon hippocampal neurotoxicity (2007) (77)
- Enhanced delayed matching performance in younger and older macaques administered the 5-HT4 receptor agonist, RS 17017 (1998) (77)
- Repeated exposures to low-level chlorpyrifos results in impairments in sustained attention and increased impulsivity in rats. (2010) (74)
- Role of Central Cholinergic Neurons in Experimental Hypertension (1980) (72)
- Effects of chronic, low-level organophosphate exposure on delayed recall, discrimination, and spatial learning in monkeys and rats. (1998) (72)
- Cotinine, a neuroactive metabolite of nicotine: potential for treating disorders of impaired cognition. (2006) (72)
- Neuronal nicotinic receptor subtypes: defining therapeutic targets. (2004) (69)
- Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. I (1997) (68)
- Chronic, low-level exposure to diisopropylfluorophosphate causes protracted impairment of spatial navigation learning (1997) (67)
- Clonidine enhances delayed matching-to-sample performance by young and aged monkeys (1991) (67)
- Reversal of Scopolamine-Induced Deficits in Navigational Memory Performance by the Seed Oil of Celastrus paniculatus (1996) (66)
- Nitric Oxide Synthase Inhibition Impairs Spatial Navigation Learning and Induces Conditioned Taste Aversion (1997) (65)
- Animal Models of Cognitive Impairment (2006) (64)
- Effects of (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a selective ligand for nicotinic acetylcholine receptors, in tests of visual attention and distractibility in rats and monkeys. (2002) (63)
- The potential role of cotinine in the cognitive and neuroprotective actions of nicotine. (2003) (63)
- Chlorpyrifos, chlorpyrifos-oxon, and diisopropylfluorophosphate inhibit kinesin-dependent microtubule motility. (2007) (63)
- Scopolamine reversal of nicotine enhanced delayed matching-to-sample performance in monkeys (1993) (62)
- Deficits in spatial learning and nicotinic–acetylcholine receptors in older, spontaneously hypertensive rats (2000) (61)
- The Revival of Scopolamine Reversal for the Assessment of Cognition-Enhancing Drugs (2009) (60)
- Role of medullary I1-imidazoline and alpha 2-adrenergic receptors in the antihypertensive responses evoked by central administration of clonidine analogs in conscious spontaneously hypertensive rats. (1995) (60)
- The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures. (2010) (59)
- The scopolamine-reversal paradigm in rats and monkeys: the importance of computer-assisted operant-conditioning memory tasks for screening drug candidates (2008) (56)
- Clonidine protection from the toxicity of soman, an organophosphate acetylcholinesterase inhibitor, in the mouse. (1986) (56)
- Antinociceptive effect of spinal cholinergic stimulation: interaction with substance P. (1989) (56)
- Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties. (1997) (53)
- SIB-1553A, (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride, a subtype-selective ligand for nicotinic acetylcholine receptors with putative cognitive-enhancing properties: effects on working and reference memory performances in aged rodents and nonhuman primates. (2001) (53)
- Neuropharmacologic and behavioral actions of clonidine: interactions with central neurotransmitters. (1992) (52)
- The nicotine metabolite, cotinine, attenuates glutamate (NMDA) antagonist-related effects on the performance of the five choice serial reaction time task (5C-SRTT) in rats. (2012) (51)
- Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo. (2002) (50)
- Mechanism of the antihypertensive action of clonidine on the pressor response to physostigmine. (1980) (50)
- Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys. (2007) (49)
- The preclinical pharmacological profile of WAY-132983, a potent M1 preferring agonist. (2000) (49)
- Dose‐specific improvements in memory‐related task performance by rats and aged monkeys administered the nicotinic‐cholinergic antagonist mecamylamine (1999) (49)
- A comparison of the inhibitory effects of clonidine and guanfacine on the behavioral and autonomic components of morphine withdrawal in rats. (1984) (48)
- Improvement in performance of a delayed matching-to-sample task by monkeys following ABT-418: a novel cholinergic channel activator for memory enhancement (1995) (48)
- Selective serotonin 5-HT2A receptor antagonist EMD 281014 improves delayed matching performance in young and aged rhesus monkeys (2005) (47)
- Effects of concomitant cholinergic and adrenergic stimulation on learning and memory performance by young and aged monkeys. (1993) (47)
- Cardiovascular changes during morphine withdrawal in the rat: Effects of clonidine (1983) (46)
- Cholinergic modulation of working memory activity in primate prefrontal cortex. (2011) (44)
- Correlation of the amnestic effects of nicotinic antagonists with inhibition of regional brain acetylcholine synthesis in rats. (1991) (43)
- Spinal cholinergic neurons and the expression of morphine withdrawal symptoms in the rat (1987) (42)
- Supraspinal and spinal mediation of naloxone-induced morphine withdrawal in rats (1985) (42)
- Improvement in accuracy of delayed recall in aged and non-aged, mature monkeys after intramuscular or transdermal administration of the CNS nicotinic receptor agonist ABT-418 (1997) (40)
- Age-related differences in distractibility and response to methylphenidate in monkeys. (1998) (39)
- The effects of JWB1-84-1 on memory-related task performance by amyloid Aβ transgenic mice and by young and aged monkeys (2007) (39)
- The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys (2004) (39)
- Relative levels of cytoprotection produced by analogs of choline and the role of α7‐nicotinic acetylcholine receptors (2003) (38)
- Disconnection between activation and desensitization of autonomic nicotinic receptors by nicotine and cotinine (2007) (38)
- Preclinical Pharmacology of ABT‐418: A Prototypical Cholinergic Channel Activator for the Potential Treatment of Alzheimer's Disease (1995) (36)
- Changes in Cholinergic Parameters Associated with Failure of Conotruncal Septation in Embryonic Chick Hearts after Neural Crest Ablation (1985) (36)
- Mechanisms involved in the cardiovascular response to intracerebroventricular injection of noradrenaline and phentolamine (1977) (34)
- Estimation of working memory in macaques for studying drugs for the treatment of cognitive disorders. (2008) (34)
- Mechanism of the hypertensive response to central injection of nicotine in conscious rats (1993) (34)
- Spinal NMDA receptor — nitric oxide mediation of the expression of morphine withdrawal symptoms in the rat (1995) (34)
- Protractive effects of chronic treatment with an acutely sub-toxic regimen of diisopropylflurophosphate on the expression of cholinergic receptor densities in rats (2000) (34)
- Ganglioside metabolism in a transgenic mouse model of Alzheimer's disease: expression of Chol-1α antigens in the brain (2010) (33)
- Differential improvement in memory-related task performance with nicotine by aged male and female rhesus monkeys. (1999) (33)
- Potential cognitive actions of (n-propargly-(3r)-aminoindan-5-yl)-ethyl, methyl carbamate (tv3326), a novel neuroprotective agent, as assessed in old rhesus monkeys in their performance of versions of a delayed matching task (2003) (33)
- Anti-RAGE and Abeta immunoglobulin levels are related to dementia level and cognitive performance. (2009) (32)
- Cognitive effects of nicotinic cholinergic receptor agonists in nonhuman primates (1996) (32)
- Mechanism of the clonidine-induced protection against acetylcholinesterase inhibitor toxicity. (1982) (32)
- Participation of different brain regions in the anti-narcotic withdrawal action of clonidine in the dependent rat (1990) (32)
- Repeated, intermittent exposures to diisopropylfluorophosphate in rats: protracted effects on cholinergic markers, nerve growth factor-related proteins, and cognitive function (2011) (30)
- The acute effects of dimebolin, a potential Alzheimer's disease treatment, on working memory in rhesus monkeys (2011) (30)
- Autoradiographic comparison of muscarinic M1 and M2 binding sites in the CNS of spontaneously hypertensive and normotensive rats (1997) (30)
- Delayed Matching-to-Sample in Monkeys as a Model for Learning and Memory Deficits: Role of Brain Nicotinic Receptors (1989) (30)
- Regional brain acetylcholine kinetics: effects of reserpine. (1979) (29)
- A computer-assisted cognitive test battery for aged monkeys (2002) (27)
- Effect of the use-dependent, nicotinic receptor antagonist BTMPS in the forced swim test and elevated plus maze after cocaine discontinuation in rats (2010) (27)
- Memory-related task performance by aged rhesus monkeys administered the muscarinic M1-preferring agonist, talsaclidine (2002) (27)
- Prevention of precipitated withdrawal symptoms by activating central cholinergic systems during a dependence-producing schedule of morphine in rats (2000) (26)
- Enhanced attention in rhesus monkeys as a common factor for the cognitive effects of drugs with abuse potential (2003) (26)
- Role of α7 Nicotinic Acetylcholine Receptors in the Pressor Response to Intracerebroventricular Injection of Choline: Blockade by Amyloid Peptide Aβ1-42 (2004) (25)
- Hypertension following intrathecal injection of cholinergic agonists in conscious rats: role of endogenous acetylcholine. (1988) (25)
- Sex dimorphisms in the cognitive-enhancing action of the Alzheimer’s drug donepezil in aged Rhesus monkeys (2003) (25)
- Inhibition of regional brain acetylcholine biosynthesis by clonidine in spontaneously hypertensive rats (1984) (24)
- Donepezil-induced improvement in delayed matching accuracy by young and old rhesus monkeys (2007) (24)
- Long-term behavioral and learning abnormalities produced by the irreversible cholinesterase inhibitor soman: effect of a standard pretreatment regimen and clonidine. (1990) (23)
- Effect of β-Amyloid Peptide 1-42 on the Cytoprotective Action Mediated by α7 Nicotinic Acetylcholine Receptors in Growth Factor-Deprived Differentiated PC-12 Cells (2003) (23)
- Autoimmunity in Alzheimers Disease as Evidenced by Plasma Immunoreactivity Against RAGE and Aβ42: Complication of Diabetes (2006) (23)
- Behavioral effects of toxic doses of soman, an organophosphate cholinesterase inhibitor, in the rat: Protection afforded by clonidine (1988) (23)
- Clonidine protection from soman and echothiophate toxicity in mice. (1986) (23)
- Dorsal root lesions block the expression of morphine withdrawal elicited from the rat spinal cord (1985) (22)
- Isoarecolone‐induced enhancement of delayed matching to sample performance in monkeys: role of nicotinic receptors (1995) (22)
- Hippocampal CA1 cell loss in a non-human primate model of transient global ischemia: A pilot study (2007) (22)
- An Aqueous Orally Active Vaccine Targeted Against a RAGE/AB Complex as a Novel Therapeutic for Alzheimer’s Disease (2012) (22)
- Dahl salt-sensitive and salt-resistant rats: examination of learning and memory performance, blood pressure, and the expression of central nicotinic acetylcholine receptors (2001) (21)
- Role of spinal and supraspinal muscarinic receptors in the expression of morphine withdrawal symptoms in the rat (1993) (20)
- The sympathoexcitatory response following selective activation of a spinal cholinergic system in anesthetized rats. (1991) (20)
- Effects of scopolamine on visual evoked potentials in aging and dementia. (1991) (20)
- Multifunctional receptor-directed drugs for disorders of the central nervous system (2011) (20)
- The induction of surface β-amyloid binding proteins and enhanced cytotoxicity in cultured PC-12 and IMR-32 cells by advanced glycation end products (2006) (20)
- Spinal muscarinic cholinergic and nitric oxide systems in cardiovascular regulation. (1996) (20)
- Role of cholinergic neurons in the cardiovascular responses evoked by central injection of bradykinin or angiotensin II in conscious rats. (1985) (20)
- Effect of chronic central treatment with the acetylcholine analog methylcarbamylcholine on cortical nicotinic receptors: correlation between receptor changes and behavioral function. (1994) (20)
- Inhibition of nerve growth factor signaling by peroxynitrite (2001) (19)
- Nitric Oxide Synthase Inhibition Impairs Delayed Recall in Mature Monkeys (1997) (19)
- Potentiation of the carotid artery occlusion reflex by a cholinergic system in the posterior hypothalamic nucleus. (1982) (19)
- Contribution of pre- and post-synaptic components to heightened central cholinergic activity in spontaneously hypertensive rats (1989) (19)
- Effects of acetylcholine in the pulmonary circulation of rabbits. (1984) (19)
- Ranitidine analog, JWS‐USC‐75IX, enhances memory‐related task performance in rats (1999) (19)
- Inhibition of the morphine withdrawal syndrome by a novel muscarinic antagonist (4-DAMP). (1991) (19)
- Adrenergic agonists protect against soman, an irreversible acetylcholinesterase inhibitor. (1987) (18)
- Methods of Behavior Analysis in Neuroscience, Second Edition (2008) (18)
- Role of prostanoids in the regulation of central cholinergic receptor sensitivity. (1993) (18)
- The hypertensive response to injection of physostigmine into the hypothalamus of the unanesthetized rat. (1978) (18)
- Relationship between the induction of RAGE cell-surface antigen and the expression of amyloid binding sites (2007) (17)
- The 5‐HT3 receptor antagonist, RS‐56812, enhances delayed matching performance in monkeys (1996) (17)
- Autoimmunity in Alzheimer's disease as evidenced by plasma immunoreactivity against RAGE and Abeta42: complication of diabetes. (2006) (17)
- The pressor response to spinal cholinergic stimulation in spontaneously hypertensive rats (1990) (16)
- Brain neurotransmitters and the development and maintenance of experimental hypertension. (1986) (16)
- Inhibitory Avoidance Behavior and Memory Assessment (2000) (16)
- Kinetics of [3H]choline and [3H]acetylcholine metabolism in several regions of rat brain following intracerebroventricular injection of [3H]choline. Effects of haloperidol. (1982) (16)
- Cognitive Enhancing Drugs (2012) (16)
- Inhibition of nerve growth factor signaling by peroxynitrite. (2001) (15)
- Protection afforded by clonidine from the acute and chronic behavioral toxicity produced by the cholinesterase inhibitor soman. (1989) (15)
- Emerging cognitive enhancing drugs (2009) (15)
- Clonidine prevents the short-term down regulation of muscarinic receptors in mouse brain induced by the acetylcholinesterase inhibitor soman (1987) (15)
- Effects of stimulation or blockade of central nicotinic-cholinergic receptors on performance of a novel version of the rat stimulus discrimination task (2005) (15)
- Effect of amyloid peptides on the increase in TrkA receptor expression induced by nicotine in vitro and in vivo (2007) (14)
- Adaptive changes in M1 muscarinic receptors localized to specific rostral brain regions during and after morphine withdrawal (2000) (14)
- Cholinergic neurons and the cardiovascular response produced by central injection of substance P in the normotensive rat. (1986) (14)
- Cytotoxicity of Aβ 1-42, RAGE23-54, and An Aβ -RAGE Complex in PC-12 Cells (2007) (13)
- Alterations in the expression of the genes encoding specific muscarinic receptor subtypes in the hypothalamus of spontaneously hypertensive rats. (1995) (13)
- Increased expression of M2 muscarinic receptor mRNA and binding sites in the rostral ventrolateral medulla of spontaneously hypertensive rats (1997) (13)
- A rapid microtechnique for the estimation of muscarinic and nicotinic receptor binding parameters using 96-well filtration plates (1995) (12)
- (–)‐Nicotine increases mRNA encoding G3PDH and the vesicular acetylcholine transporter in vivo (1998) (12)
- Spinal muscarinic, glutamatergic and GABAergic receptor systems in cardiovascular regulation. (1997) (12)
- Effects of concomitant cholinergic and adrenergic stimulation on learning and memory performance by primates. (1992) (12)
- Protracted cognitive effects produced by clonidine in Macaca nemestrina performing a delayed matching task (2008) (11)
- Regulation of central muscarinic receptors after cholinesterase inhibition: Effect of clonidine (1993) (11)
- Inhibition of brain acetylcholine biosynthesis by methyldopa in spontaneously hypertensive rats (1984) (11)
- A 24-h access I.V. self-administration schedule of morphine reinforcement and the estimation of recidivism: Pharmacological modification by arecoline (2007) (11)
- Effect of Intrathecal Pretreatment With the Neurokinin Receptor Antagonist CP-99994 on the Expression of Naloxone-Precipitated Morphine Withdrawal Symptoms (1997) (11)
- Protection by clonidine from the cardiovascular changes and lethality following soman administration in the rat: role of brain acetylcholine. (1988) (11)
- Novel analogs of choline as potential neuroprotective agents. (2005) (10)
- Effect of administration of the nicotinic acetylcholine receptor antagonist BTMPS, during nicotine self-administration, on lever responding induced by context long after withdrawal (2010) (10)
- The effect of the acetylcholine transport blocker vesamicol on central cholinergic pressor neurons (1991) (10)
- The induction of surface beta-amyloid binding proteins and enhanced cytotoxicity in cultured PC-12 and IMR-32 cells by advanced glycation end products. (2006) (10)
- Prevention of morphine-induced muscarinic (M2) receptor adaptation suppresses the expression of withdrawal symptoms (1998) (10)
- Pharmacological analysis of the enhanced pressor response to central cholinergic stimulation in spontaneously hypertensive rats. (1990) (10)
- The Prototypical Ranitidine Analog JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models (2011) (10)
- Modification of spino-bulbar autonomic cholinergic systems by activation of alpha-adrenergic receptors. (1989) (10)
- Comparison of the ability of direct‐ and indirect‐acting nicotinic agonists to induce nicotinic receptor up‐regulation in rat cerebral cortex (1994) (9)
- Treatments for neuropathic pain differentially affect delayed matching accuracy by macaques: Effects of amitriptyline and gabapentin (2010) (9)
- Role of alpha7 nicotinic acetylcholine receptors in the pressor response to intracerebroventricular injection of choline: blockade by amyloid peptide Abeta1-42. (2004) (9)
- Pharmacological evaluation of methylcarbamylcholine-induced drinking behavior in rats (1994) (9)
- Selective antagonism by clonidine of the stereotyped and non-stereotyped motor activity elicited by atropine (1986) (9)
- Effect of beta-amyloid peptide 1-42 on the cytoprotective action mediated by alpha7 nicotinic acetylcholine receptors in growth factor-deprived differentiated PC-12 cells. (2003) (9)
- Cognitive Pharmacology in Aging Macaques (2006) (8)
- RAGE and Aβ Immunoglobulins: Relation to Alzheimer’s disease-related cognitive function (2010) (8)
- Functional central nicotinic acetylcholine receptor antagonism by systemic administration of Tinuvin 770 (BTMPS). (2005) (8)
- Spinal cholinergic modulation of cardiovascular tone and a somatosympathetic reflex response (1991) (8)
- Cholinergic actions of false neurotransmitters: Acetyldiethylcholine (1982) (8)
- Role of central biogenic amines on the protection afforded by clonidine against the toxicity of soman, an irreversible cholinesterase inhibitor. (1988) (7)
- Velnacrine maleate improves delayed matching performance by aged monkeys (1995) (7)
- Anomaly in aortic arch alters pathological outcome of transient global ischemia in Rhesus macaques (2009) (7)
- Localization of cholinergic neurons involved in the cardiovascular response to intrathecal injection of carbachol. (1993) (7)
- Cholinergic actions f false neurotransmitters: acetylpyrrolidinecholine (1981) (7)
- Precursors of cholinergic false transmitters: Central effects on blood pressure and direct interactions with cholinergic receptors (1988) (7)
- Cholinergic false transmitters: Physiological and biochemical actions in central and peripheral systems (1988) (7)
- Excitatory modulation by a spinal cholinergic system of a descending sympathoexcitatory pathway in rats (1992) (7)
- Effectiveness of alpha 2-adrenergic receptor stimulation in reducing the central toxicity following cholinesterase inhibition. (1992) (7)
- The Importance of Brainstem Cholinergic Neurons in the Pressor Response to Cocaine (2005) (6)
- MHP-133, a Drug with Multiple CNS Targets: Potential for Neuroprotection and Enhanced Cognition (2007) (6)
- The Behavioral Assessment of Sensorimotor Processes in the Mouse: Acoustic Startle, Locomotor Activity, RotaRod, and Beam Walking (2000) (5)
- Opposing influences on behavior mediated by muscarinic and nicotinic receptors in the rat posterior hypothalamic nucleus (2004) (5)
- The use-dependent, nicotinic antagonist BTMPS reduces the adverse consequences of morphine self-administration in rats in an abstinence model of drug seeking (2011) (5)
- Co-localization of apolipoprotein E and β-amyloid in plaques and cerebral blood vessels of aged non-human primates (1998) (5)
- Cocaine‐Induced Expression Differences in Glutamate Receptor Subunits and Transporters in Amygdalae of Taste Aversion‐Prone and Taste Aversion‐Resistant Rats (2003) (5)
- In vivo and in vitro cholinesterase inhibitor property of the antitumor agent caracemide. (1990) (5)
- Nicotine and cognition in young and aged nonhuman primates (2001) (4)
- Inactivation of kallikrein and kininases and stabilization of whole rat brain kinin levels following focused microwave irradiation (1986) (4)
- Evaluation of two rodent delayed-response memory tasks A method with retractable levers versus a method with closing doors (2000) (4)
- The cholinergic hypothesis — past and present (2004) (4)
- Effect of methyldopa on brain cholinergic neurons involved in cardiovascular regulation. A study in conscious spontaneously hypertensive rats. (1984) (4)
- Localization of ubiquitin in the plaques of five aged primates by dual-label fluorescent immunohistochemistry (1997) (4)
- ABT-418: A Novel Cholinergic Channel Activator (ChCA) for the Potential Treatment of Alzheimer’s Disease (1994) (4)
- Synthesis and in vivo and in vitro evaluation of isoarecolone and derivatives (1998) (3)
- Mouse Genetic Models (2006) (3)
- Changes in regional brain synaptosomal high affinity choline uptake during the development of hypertension in spontaneously hypertensive rats (1987) (3)
- Cognitive Impairment following Traumatic Brain Injury (2006) (3)
- Influence of clonidine on experimental hypertension induced by cholinergic stimulation (1980) (3)
- Cocaine‐Induced Expression Differences of 5‐HT3 Receptors and Na+/K+‐APTase Pump Subunits in Amygdalae of Taste‐Aversion‐Prone and Taste‐Aversion‐Resistant Rats (2003) (3)
- Microinjection of vehicle into the nucleus basalis magnocellularis results in task-specific impairment of passive avoidance responding (1988) (3)
- Novel pyridinium derivatives as inhibitors for acetylcholinesterase. (1996) (3)
- Spontaneous morphine withdrawal from the rat spinal cord (1985) (2)
- α7 NNR allosteric modulation in behavioral models of cognition (2011) (2)
- ABT — 418, a Novel Nicotinic Agonist (1994) (2)
- The electromyographic signal as a presymptomatic indicator of organophosphates in the body (2006) (2)
- Long term treatment with clonidine during the development of hypertension in spontaneously hypertensive rats. (1985) (2)
- ABT-089: An Orally Effective Cholinergic Channel Modulator (ChCM) with Cognitive Enhancement and Neuroprotective Action (1997) (2)
- Drugs with multiple CNS targets (2004) (1)
- Dementia and Pharmacotherapy: Memory Drugs (2007) (1)
- Assessment of Distractibility in Non-Human Primates Performing a Delayed Matching-to-Sample Task (2000) (1)
- About the series (2006) (1)
- The use of the scopolamine-induced cognitive impairment model to translate on-target activity for ABT-894 from rodents/monkeys to humans: Preclinical evidences (2011) (1)
- Contextually Induced Drug Seeking During Protracted Abstinence in Rats (2009) (1)
- Erratum: MHP-133, a drug with multiple CNS targets: Potential for neuroprotection and enhanced cognition (Neurochemical Research 32, 7, (1224-1237) DOI: 10.1007/s11064-007-9294-0) (2007) (1)
- Neuronal nicotinic receptor agonists as potential therapeutic agents for Alzheimer's disease (1999) (1)
- Inhibition of Brain Acetylcholine Biosynthesis by Clonidine and Methyldopa: Relevance to Hypertensive Disease (1986) (0)
- O4-04-01: Prolonged cognitive enhancement exhibited by monkeys after single doses of clonidine (2008) (0)
- Altered Thioredoxin System in the Retina of Aged Mice Overexpressing Amyloid Beta (2009) (0)
- Histological and behavioral characterization of a non-human primate stroke model: A pilot study (2006) (0)
- Faculty Opinions recommendation of The endogenous cannabinoid system modulates nicotine reward and dependence. (2008) (0)
- The scopolamine-induced deficit model is a viable translational approach that can expedite decision making in clinical development: Preclinical evidence (2009) (0)
- Model Applications and Future Developments (2006) (0)
- Functional interaction of Abeta1-42 peptide with alpha7 nicotinic receptors (2001) (0)
- Stimulation of Brain Nicotinic Acetylcholine Receptors (nAChR) and Inhibition of Brain Acetylcholinesterase (AChE) Activity (1997) (0)
- An Aqueous Orally Active Vaccine Targeted Against a RAGE/AB Complex as a Novel Therapeutic for Alzheimer’s Disease (2012) (0)
- Faculty Opinions recommendation of Amyloid beta protein modulates glutamate-mediated neurotransmission in the rat basal forebrain: involvement of presynaptic neuronal nicotinic acetylcholine and metabotropic glutamate receptors. (2007) (0)
- [Table, Ordering Information]. (2009) (0)
- Conditioned Place Preference: An Approach to Evaluating Positive and Negative Drug-Induced Stimuli (2000) (0)
- Chronic Organophosphorus Exposure and Cognition. (1998) (0)
- Acetylcholine — Prostanoid Interaction in the Pulmonary Circulation (1986) (0)
- Faculty Opinions recommendation of A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. (2009) (0)
- Effect of the use‐dependent nicotinic receptor antagonist BTMPS on cocaine withdrawal (2007) (0)
- Regional brain distribution of cathepsin D activity: its inhibition in vivo following central infusion of pepstatin in the rat. (1982) (0)
- Protection against Acetylcholinesterase Inhibitor Toxicity by Alpha- Adrenergic Agonists (1992) (0)
- P2-477: Evidence for broad spectrum symptomatic efficacy across cognitive domains and potential for disease modification in Alzheimer's disease revealed by the novel alpha-7 neuronal nicotinic receptor agonist A-582941 (2008) (0)
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