Jerry Young Niederkorn

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Jerry Young Niederkorn

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Philosophy
Biology

Jerry Young Niederkorn's Degrees

Doctorate Medicine Stanford University

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Jerry Young Niederkorn's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

See no evil, hear no evil, do no evil: the lessons of immune privilege (2006) (424)
IL-17 disrupts corneal barrier following desiccating stress (2009) (347)
Desiccating Stress Induces T Cell-Mediated Sjögren’s Syndrome-Like Lacrimal Keratoconjunctivitis1 (2006) (324)
Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma. (2007) (291)
Immunosuppressive factors secreted by human amniotic epithelial cells. (2005) (279)
Immune privilege and immune regulation in the eye. (1990) (276)
Induction of anterior chamber-associated immune deviation requires an intact, functional spleen (1981) (269)
A Novel Role for TGF-β and IL-10 in the Induction of Immune Privilege (1998) (249)
The pathophysiology of Acanthamoeba keratitis. (2006) (245)
The pathogenesis of Acanthamoeba keratitis. (1999) (227)
The immune privilege of corneal allografts. (1999) (222)
Progress in Retinal and Eye Research (208)
Promotion of murine orthotopic corneal allograft survival by systemic administration of anti-CD4 monoclonal antibody. (1991) (174)
Resistance of Acanthamoeba castellanii Cysts to Physical, Chemical, and Radiological Conditions (2002) (170)
Immune privilege in the anterior chamber of the eye. (2002) (157)
Systemic immune unresponsiveness induced in adult mice by anterior chamber presentation of minor histocompatibility antigens (1980) (144)
Ocular Surface APCs Are Necessary for Autoreactive T Cell-Mediated Experimental Autoimmune Lacrimal Keratoconjunctivitis (2011) (132)
Human Uveal Melanoma Cells Produce Macrophage Migration-Inhibitory Factor to Prevent Lysis by NK Cells1 (2000) (131)
Anterior chamber-associated immune deviation promotes corneal allograft survival. (1996) (126)
Characterization of the suppressor cell(s) responsible for anterior chamber-associated immune deviation (ACAID) induced in BALB/c mice by P815 cells. (1985) (126)
Ocular disease induced in mice by anterior chamber inoculation of herpes simplex virus. (1984) (122)
Phagocytosis of particulate antigens by corneal epithelial cells stimulates interleukin-1 secretion and migration of Langerhans cells into the central cornea. (1989) (121)
Immune Mechanisms of Corneal Allograft Rejection (2007) (120)
Effect of steroids on Acanthamoeba cysts and trophozoites. (2001) (117)
Autoimmunity at the ocular surface: pathogenesis and regulation (2010) (115)
Alloantigens placed into the anterior chamber of the eye induce specific suppression of delayed-type hypersensitivity but normal cytotoxic T lymphocyte and helper T lymphocyte responses. (1983) (113)
The role of contact lenses, trauma, and Langerhans cells in a Chinese hamster model of Acanthamoeba keratitis. (1993) (113)
The immune privilege of corneal grafts (2003) (112)
A novel role for TGF-beta and IL-10 in the induction of immune privilege. (1998) (110)
Isolation and characterization of a unique natural killer cell inhibitory factor present in the anterior chamber of the eye. (1996) (109)
PD-L1: PD-1 interaction contributes to the functional suppression of T-cell responses to human uveal melanoma cells in vitro. (2008) (103)
CD4+ T-Cell–Mediated Mechanisms of Corneal Allograft Rejection: Role of Fas-Induced Apoptosis (2005) (99)
Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings. (2010) (97)
Age-related T-cell cytokine profile parallels corneal disease severity in Sjogren's syndrome-like keratoconjunctivitis sicca in CD25KO mice. (2010) (95)
The role of macrophages in Acanthamoeba keratitis. (1996) (93)
Corneal Transplantation and Immune Privilege (2013) (93)
Mannose Induces the Release of Cytopathic Factors from Acanthamoeba castellanii (1998) (93)
Inhibition of metastasis of intraocular melanomas by adenovirus-mediated gene transfer of plasminogen activator inhibitor type 1 (PAI-1) in an athymic mouse model. (1997) (91)
Pathogenic Acanthamoeba spp. Secrete a Mannose-Induced Cytolytic Protein That Correlates with the Ability To Cause Disease (2003) (89)
Role of Th1 and Th2 cells in anterior chamber‐associated immune deviation (1996) (83)
Emerging concepts in CD8(+) T regulatory cells. (2008) (82)
NK Cells Promote Th-17 Mediated Corneal Barrier Disruption in Dry Eye (2012) (82)
In vivo and in vitro collagenolytic activity of Acanthamoeba castellanii. (1990) (82)
Immune escape mechanisms of intraocular tumors (2009) (82)
IMMUNOLOGY AND IMMUNOMODULATION OF CORNEAL TRANSPLANTATION (2002) (80)
Ocular Immune Privilege Promoted by the Presentation of Peptide on Tolerogenic B Cells in the Spleen. II. Evidence for Presentation by Qa-11 (2001) (76)
High-risk corneal allografts and why they lose their immune privilege (2010) (74)
CD25+, interleukin‐10‐producing CD4+ T cells are required for suppressor cell production and immune privilege in the anterior chamber of the eye (2003) (73)
The role of cytotoxic T lymphocytes in corneal allograft rejection. (2000) (72)
Intracameral inoculation of herpes simplex virus type I induces anterior chamber associated immune deviation. (1982) (72)
Antigen presentation by Langerhans cells in vivo: donor-derived Ia+ Langerhans cells are required for induction of delayed-type hypersensitivity but not for cytotoxic T lymphocyte responses to alloantigens. (1986) (71)
Susceptibility of corneas from various animal species to in vitro binding and invasion by Acanthamoeba castellanii [corrected]. (1992) (70)
The induction of anterior chamber-associated immune deviation. (2007) (70)
Mechanisms of immune privilege in the eye and hair follicle. (2003) (70)
Autoantibodies contribute to the immunopathogenesis of experimental dry eye disease. (2012) (67)
Characterization of a plasminogen activator produced by Acanthamoeba castellanii. (1995) (65)
The effect of oral immunization on corneal allograft survival. (1996) (65)
PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation. (2009) (65)
History and Physiology of Immune Privilege (2010) (64)
Desiccating stress induces CD4+ T-cell-mediated Sjögren's syndrome-like corneal epithelial apoptosis via activation of the extrinsic apoptotic pathway by interferon-γ. (2011) (64)
Severing Corneal Nerves in One Eye Induces Sympathetic Loss of Immune Privilege and Promotes Rejection of Future Corneal Allografts Placed in Either Eye (2015) (64)
Exacerbation of Acanthamoeba Keratitis in Animals Treated with Anti-Macrophage Inflammatory Protein 2 or Antineutrophil Antibodies (2001) (62)
A pig model of Acanthamoeba keratitis: transmission via contaminated contact lenses. (1992) (62)
Fate of MHC-matched corneal allografts in Th1-deficient hosts. (2004) (61)
Role of TRAIL and IFN-γ in CD4+ T Cell-Dependent Tumor Rejection in the Anterior Chamber of the Eye 1 (2003) (61)
Destructive and nondestructive patterns of immune rejection of syngeneic intraocular tumors. (1987) (61)
Peripheral Tolerance Via the Anterior Chamber of the Eye: Role of B Cells in MHC Class I and II Antigen Presentation1 (2006) (60)
The Th1/Th2 paradigm in ocular allergy (2005) (59)
Enucleation in consort with immunologic impairment promotes metastasis of intraocular melanomas in mice. (1984) (59)
Role of Contact Lens Wear, Bacterial Flora, and Mannose-Induced Pathogenic Protease in the Pathogenesis of Amoebic Keratitis (2005) (59)
Role of interferon-γ in a mouse model of allergic conjunctivitis (2005) (59)
Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion. (2007) (58)
Ocular Immune Privilege and Ocular Melanoma: Parallel Universes or Immunological Plagiarism? (2012) (58)
The immunobiology of Acanthamoeba keratitis. (1999) (58)
Pathways of corneal and ocular surface inflammation: a perspective from the cullen symposium. (2005) (57)
Effects of mannose on Acanthamoeba castellanii proliferation and cytolytic ability to corneal epithelial cells. (2003) (57)
Cutting Edge: Atopy Promotes Th2 Responses to Alloantigens and Increases the Incidence and Tempo of Corneal Allograft Rejection1 (2005) (56)
γδ T Cells Promote Anterior Chamber-Associated Immune Deviation and Immune Privilege through Their Production of IL-101 (2006) (56)
In vitro expanded CD4+CD25+Foxp3+ regulatory T cells maintain a normal phenotype and suppress immune-mediated ocular surface inflammation. (2008) (56)
Intracamerally induced concomitant immunity: mice harboring progressively growing intraocular tumors are immune to spontaneous metastases and secondary tumor challenge. (1983) (54)
Immune Privilege of Corneal Allografts (2010) (54)
CD4+ T-Cell–Independent Rejection of Corneal Allografts (2006) (53)
Advances on Non-CD4 + Foxp3+ T Regulatory Cells: CD8+, Type 1, and Double Negative T Regulatory Cells in Organ Transplantation (2015) (53)
Effect of cytokine-induced migration of Langerhans cells on corneal allograft survival (1995) (53)
Characterization and pathogenic potential of a soil isolate and an ocular isolate of Acanthamoeba castellanii in relation to Acanthamoeba keratitis. (1992) (53)
Failure of Acanthamoeba castellanii to produce intraocular infections. (2005) (53)
IL-17A–Dependent CD4+CD25+ Regulatory T Cells Promote Immune Privilege of Corneal Allografts (2011) (52)
Disruption of TGF-β Signaling Improves Ocular Surface Epithelial Disease in Experimental Autoimmune Keratoconjunctivitis Sicca (2011) (52)
Role of mucosal IgA in the resistance to Acanthamoeba keratitis. (1998) (51)
Expression of a nonclassical MHC class Ib molecule in the eye. (1999) (51)
Differential expression of chemokine receptors on uveal melanoma cells and their metastases. (2008) (50)
Chemotactic response of macrophages to Acanthamoeba castellanii antigen and antibody-dependent macrophage-mediated killing of the parasite. (1992) (50)
Effect of alloantibodies on corneal allograft survival. (2002) (50)
Monoclonal IgA antibodies protect against Acanthamoeba keratitis. (1999) (49)
Splenic B cells act as antigen presenting cells for the induction of anterior chamber-associated immune deviation. (2003) (48)
Cornea: Window to Ocular Immunology. (2011) (48)
Mechanisms of Corneal Graft Rejection: The Sixth Annual Thygeson Lecture, Presented at the Ocular Microbiology and Immunology Group Meeting, October 21, 2000 (2001) (47)
Effect of LFA-1 and ICAM-1 antibody treatment on murine corneal allograft survival. (1994) (45)
ANALYSIS OF ANTIBODY PRODUCTION INDUCED BY ALLOGENEIC TUMOR CELLS INOCULATED INTO THE ANTERIOR CHAMBER OF THE EYE (1982) (45)
Immunologic evaluation of spontaneous regression of an intraocular murine melanoma. (1990) (44)
Systemic immune response to Acanthamoeba keratitis in the Chinese hamster. (1997) (44)
Successful Immunization Against Acanthamoeba Keratitis in a Pig Model (1995) (44)
Heterotopic corneal grafting in mice: a new approach to the study of corneal alloimmunity. (1982) (44)
IL-17 Promotes Immune Privilege of Corneal Allografts (2010) (43)
Preliminary findings in corneal allograft rejection in patients with keratoconus. (2003) (43)
Spontaneous autoimmune dacryoadenitis in aged CD25KO mice. (2010) (43)
Role of interferon-gamma in a mouse model of allergic conjunctivitis. (2005) (42)
Anterior chamber-associated immune deviation. (1999) (42)
Adaptive immune responses to Acanthamoeba cysts. (2002) (42)
New Twists to an Old Story: Novel Concepts in the Pathogenesis of Allergic Eye Disease (2013) (41)
Immune regulatory mechanisms in allergic conjunctivitis: insights from mouse models (2008) (41)
Two different regulatory T cell populations that promote corneal allograft survival. (2010) (41)
In vitro and in vivo tumoricidal properties of a pathogenic/free-living amoeba. (1993) (40)
CD8+ Cells Regulate the T helper-17 Response in an Experimental Murine Model of Sjögren Syndrome (2013) (39)
Evaluation of ocular surface inflammation in the presence of dry eye and allergic conjunctival disease. (2005) (39)
Ultrastructural and immunohistological characterization of the sirc corneal cell line (1990) (37)
Are corneal cells susceptible to antibody-mediated killing in corneal allograft rejection? (2003) (37)
Evidence that the fate of class II-disparate corneal grafts is determined by the timing of class II expression. (1991) (36)
In vitro characterization of Acanthamoeba castellanii cytopathic effect. (1995) (36)
Inhibition of chemokine receptor expression on uveal melanomas by CXCR4 siRNA and its effect on uveal melanoma liver metastases. (2009) (36)
Pathobiology and Immunobiology of Acanthamoeba Keratitis: Insights from Animal Models  (2017) (36)
THE INTERACTION OF ACANTHAMOEBA CASTELLANII CYSTS WITH MACROPHAGES AND NEUTROPHILS (2002) (35)
Oral immunisation as a strategy for enhancing corneal allograft survival (1997) (35)
The immunobiology of Acanthamoeba keratitis. (2006) (35)
Suppressed cellular immunity in mice harboring intraocular melanomas. (1984) (35)
Apoptosis as a mechanism of cytolysis of tumor cells by a pathogenic free-living amoeba (1994) (35)
Impact of oral immunization with Acanthamoeba antigens on parasite adhesion and corneal infection. (1998) (35)
The immunogenic privilege of corneal allografts. (1989) (35)
NKT cell exacerbation of liver metastases arising from melanomas transplanted into either the eyes or spleens of mice. (2011) (35)
Histopathology of rejected orthotopic corneal grafts in the rat. (1989) (34)
Antibody-dependent neutrophil-mediated killing of Acanthamoeba castellanii. (1994) (33)
Immunoregulation of intraocular tumours (1997) (33)
Immunogenicity and immune privilege of corneal allografts. (2007) (33)
Regional immunity and immune privilege. (2007) (32)
Apoptosis as a mechanism of cytolysis of tumor cells by a pathogenic free-living amoeba. (1994) (32)
Oral Immunization with Acanthamoeba castellanii Mannose-Binding Protein Ameliorates Amoebic Keratitis (2006) (32)
Corneal allografts induce cytotoxic T cell but not delayed hypersensitivity responses in mice. (1985) (32)
Induction of anterior chamber-associated immune deviation (ACAID) by allogeneic intraocular tumors does not require splenic metastases. (1982) (31)
Development, Alteration and Real Time Dynamics of Conjunctiva-Associated Lymphoid Tissue (2013) (31)
Expression and possible function of IL-2 and IL-15 receptors on human uveal melanoma cells. (2004) (31)
Immune privilege of the eye and fetus: parallel universes? (2005) (31)
Expression of HLA class I and II antigens on cells of the human trabecular meshwork. (1987) (31)
Enucleation-induced metastasis of intraocular melanomas in mice. (1984) (31)
Spontaneous immune rejection of intraocular tumors in mice. (1985) (31)
The immunology of corneal transplantation. (1999) (31)
Phenotypic analysis of oral tolerance to alloantigens: evidence that the indirect pathway of antigen presentation is involved1 (2002) (29)
Anterior chamber–associated immune deviation and its impact on corneal allograft survival (2006) (28)
CD4+ T‐cell‐dependent tumour rejection in an immune‐privileged environment requires macrophages (2008) (28)
Allergic Airway Hyperreactivity Increases the Risk for Corneal Allograft Rejection (2009) (28)
Role of tumor necrosis factor receptor expression in anterior chamber-associated immune deviation (ACAID) and corneal allograft survival. (2004) (28)
Expansion of B Cells Is Necessary for the Induction of T-Cell Tolerance Elicited through the Anterior Chamber of the Eye (2007) (27)
The role of the innate and adaptive immune responses in Acanthamoeba keratitis. (2002) (27)
Regulatory T cells and the eye. (2007) (26)
Reduction of liver metastasis of intraocular melanoma by interferon-beta gene transfer. (2003) (26)
Differential Roles of CD8+ and CD8− T Lymphocytes in Corneal Allograft Rejection in ‘High‐Risk’ Hosts (2006) (26)
Feline uveal melanomas induced with feline sarcoma virus: potential model of the human counterpart. (1981) (25)
Conditions affecting enhanced corneal allograft survival by oral immunization. (1998) (24)
Prevention of the induction of allospecific cytotoxic T lymphocyte and delayed-type hypersensitivity responses by ultraviolet irradiation of corneal allografts. (1990) (23)
Downregulation of survivin expression enhances sensitivity of cultured uveal melanoma cells to cisplatin treatment. (2006) (23)
T cell subsets in the immune rejection of murine heterotopic corneal allografts. (1986) (22)
Allergic Conjunctivitis Exacerbates Corneal Allograft Rejection by Activating Th1 and Th2 Alloimmune Responses (2010) (22)
Spontaneous corneal neovascularization in nude mice. Local imbalance between angiogenic and anti-angiogenic factors. (1993) (22)
Effect of immunization with the mannose-induced Acanthamoeba protein and Acanthamoeba plasminogen activator in mitigating Acanthamoeba keratitis. (2007) (22)
Role of suppressor T cells in herpes simplex virus-induced immune deviation (1984) (21)
NKT cells are necessary for maximal expression of allergic conjunctivitis. (2010) (21)
The nature of antigen in the eye has a profound effect on the cytokine milieu and resultant immune response (1998) (20)
Immune Response and the Eye (2007) (20)
Role of NKT cells in anterior chamber-associated immune deviation (2003) (20)
The immunopathology of intraocular tumour rejection (1991) (20)
Immunological analysis of a destructive pattern of intraocular tumor resolution. (1988) (20)
Efferent blockade of delayed-type hypersensitivity responses in the anterior chamber of the eye. (1990) (20)
Class I disparate corneal grafts enjoy afferent but not efferent blockade of the immune response. (1991) (20)
NKT cells act through third party bone marrow‐derived cells to suppress NK cell activity in the liver and exacerbate hepatic melanoma metastases (2015) (20)
ROLE OF ACTIVATED MACROPHAGES IN ACANTHAMOEBA KERATITIS (2004) (19)
Paradigm shifts in the role of CD4+ T cells in keratoplasty. (2010) (19)
Interleukin-1 abrogates anterior chamber-associated immune deviation. (1990) (19)
Trichinella pseudospiralis larvae express natural killer (NK) cell-associated asialo-GM1 antigen and stimulate pulmonary NK activity (1988) (19)
Adoptive transfer of immunity to intraocular tumors in mice. (1984) (19)
Uveal melanoma expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors and susceptibility to TRAIL-induced apoptosis. (2004) (18)
γδ T cells are required for maximal expression of allergic conjunctivitis. (2011) (18)
Immunology of intraocular tumors. (2005) (18)
High-risk Corneal Allografts Are Capable of Stimulating Complement Dependent Cytolytic Antibodies (2000) (18)
In situ suppression of delayed-type hypersensitivity: another mechanism for sustaining the immune privilege of the anterior chamber. (1991) (17)
Effect of donor Langerhans cells on corneal graft rejection. (1992) (17)
Trichinella spiralis and Trichinella pseudospiralis induce collagen synthesis by host fibroblasts in vitro and in vivo. (1995) (17)
The diagnosis and management of Acanthamoeba keratitis. (2000) (17)
CD8+ T Cells Circumvent Immune Privilege in the Eye and Mediate Intraocular Tumor Rejection by a TNF-α-Dependent Mechanism1 (2007) (17)
Lymphoma allografts abrogate immune privilege within the anterior chamber of the eye. (1986) (17)
Emergence of a dominant cytotoxic T lymphocyte antitumor effector from tumor-infiltrating cells in the anterior chamber of the eye (1990) (17)
The presence of donor-derived class II-positive cells abolishes immune privilege in the anterior chamber of the eye. (1991) (17)
Modulation of corneal and stromal matrix metalloproteinase by the mannose-induced Acanthamoeba cytolytic protein. (2008) (17)
Immune privilege in the anterior chamber of the eye: alloantigens and tumour-specific antigens presented into the anterior chamber simultaneously induce suppression and activation of delayed hypersensitivity to the respective antigens. (1992) (16)
Presentation of the H-Y antigen on Langerhans' cell-negative corneal grafts downregulates the cytotoxic T cell response and converts responder strain mice into phenotypic nonresponders (1988) (16)
Third International Workshop on Langerhans cells: discussion overview. (1992) (16)
Immunogenetic basis for immunologic privilege in the anterior chamber of the eye (2004) (16)
Role of IFN‐γ in the establishment of anterior chamber‐associated immune deviation (ACAID)‐induced CD8+ T regulatory cells (2012) (16)
Resistance and susceptibility of human uveal melanoma cells to TRAIL-induced apoptosis. (2004) (15)
IFN‐γ Blocks CD4+CD25+ Tregs and Abolishes Immune Privilege of Minor Histocompatibility Mismatched Corneal Allografts (2013) (15)
EXOGENOUS RECOMBINANT INTERLEUKIN‐2 ABROGATES ANTERIOR‐CHAMBER‐ASSOCIATED IMMUNE DEVIATION (1987) (15)
T cell subsets involved in the rejection of metastases arising from intraocular melanomas in mice. (1987) (14)
Enhanced pulmonary natural killer cell activity during murine encephalitozoonosis. (1985) (14)
Promotion of corneal allograft survival with leflunomide. (1994) (14)
REVIEW Immunology of Intraocular Tumors (2005) (13)
The biology of Acanthamoeba keratitis. (2020) (13)
The Eye Sees Eye to Eye With the Immune System: The 2019 Proctor Lecture (2019) (13)
Intracorneal instillation of latex beads induces macrophage-dependent protection against Acanthamoeba keratitis. (2006) (13)
CD8+ T cells circumvent immune privilege in the eye and mediate intraocular tumor rejection by a TNF-alpha-dependent mechanism. (2007) (13)
Histopathologic analysis of intraocular allogeneic tumors in mice. (1985) (12)
Role of Fas ligand in uveal melanoma-induced liver damage (2001) (12)
Reduction of enucleation-induced metastasis in intraocular melanoma by periorbital irradiation. (1987) (12)
Suicide enzyme inhibition as a chemotherapeutic strategy for controlling metastases derived from intraocular melanomas. (1987) (12)
Effect of Corneal Nerve Ablation on Immune Tolerance Induced by Corneal Allografts, Oral Immunization, or Anterior Chamber Injection of Antigens (2017) (12)
Role of interferon‐γ and cytotoxic T lymphocytes in intraocular tumor rejection (2016) (12)
The immunopathogenesis of ocular tumors (1995) (12)
Ocular immune privilege is circumvented by CD4+ T cells, leading to the rejection of intraocular tumors in an IFN‐γ‐dependent manner (2007) (12)
Epigenetic regulation of CXCR4 expression by the ocular microenvironment. (2013) (11)
Vascularization of corneas of hairless mutant mice. (1990) (11)
ACCEPTANCE OF H‐Y‐DISPARATE CORNEAL GRAFTS DESPITE CONCOMITANT IMMUNIZATION OF THE RECIPIENT (1991) (11)
Abrogating TNF-α expression prevents bystander destruction of normal tissues during iNOS-mediated elimination of intraocular tumors. (2011) (11)
Rationale for immune response and the eye. (2007) (11)
IFN– Promotes Goblet Cell Loss in Response to Desiccating Ocular Stress (2006) (11)
Immunology of Corneal Allografts: Insights from Animal Models. (2015) (11)
Growth and Metastasis of Intraocular Tumors in Aged Mice (2016) (10)
Effect of transforming growth factor-beta on plasminogen activator production of cultured human uveal melanoma cells. (1996) (10)
Immune privilege in the anterior chamber of the eye is not extended to intraocular Listeria monocytogenes. (1997) (9)
Regional differences in immune regulation: The immunogenic privilege of corneal allografts (1988) (9)
Trichinella pseudospiralis overcomes innate resistance of the chinese hamster to Trichinella spiralis (1991) (9)
Promotion of syngeneic intraocular tumor growth in mice by anterior chamber-associated immune deviation. (1983) (9)
MHC matching improves corneal allograft survival in mice with Th2-immune bias. (2002) (9)
Induction of Contrasuppressor Cells and Loss of Immune Privilege Produced by Corneal Nerve Ablation (2018) (8)
Corneal Nerve Ablation Abolishes Ocular Immune Privilege by Downregulating CD103 on T Regulatory Cells (2020) (8)
Effect of acute versus chronic Trichinella pseudospiralis infections on systemic cell-mediated immunity. (1991) (8)
Efficacy of Dacarbazine (DTIC) in preventing metastases arising from intraocular melanomas in mice (1992) (8)
Reconsidering the immunologic privilege and lymphatic drainage of the anterior chamber of the eye. (1989) (8)
Induction of anterior chamber-associated immune deviation (acaid) does not require splenic metastasis of allogenic intraocular tumors. Abstr. (1982) (8)
Spontaneous Autoimmune Inflammation of the Ocular Surface Mucosa in Aged CD4-DNTGFβRII Mice (2011) (7)
Effect of Langerhans' cells on cytotoxic T lymphocyte responses to major and minor alloantigens expressed on heterotopic corneal allografts. (1987) (6)
Prevention of metastasis of intraocular melanoma in mice treated with difluoromethylornithine (2004) (6)
Role of tear anti-acanthamoeba IgA in Acanthamoeba keratitis. (2000) (5)
Immunology of Uveal Melanoma: Immunosuppressive Factors and the Basis for Immunotherapy (2003) (5)
NK cells in the eye (2010) (5)
Deviant immune responses to allogeneic tumor cells placed into the anterior chamber protect the intraocular neoplasm, but prevent metastases. (1983) (5)
Dynamic Immunoregulatory Processes that Sustain Immune Privilege in the Eye (2010) (5)
'Subthreshold stimulation' of allospecific delayed hypersensitivity by corneal allografts. (1993) (5)
IFN‐γ‐independent intraocular tumor rejection is mediated by a macrophage‐dependent process that leaves the eye intact (2012) (5)
Dose distribution around a 3.0-mm type 6702 I-125 seed. (1990) (5)
Is cataract formation an autoimmune phenomenon? (1987) (4)
A renewed appreciation for ocular immune privilege. (2005) (4)
Abrogation of anterior-chamber-induced suppression of delayed-type hypersensitivity responses by monoclonal anti-I-J antibodies. (1984) (4)
Immune privilege of the eye (2003) (4)
Corneal immune privilege. (2005) (4)
Natural Killer T Cells Contribute to Neutrophil Recruitment and Ocular Tissue Damage in a Model of Intraocular Tumor Rejection (2016) (4)
A mechanism for anti-asialo GM 1 antibody-induced anaphylactoid response in mice infected with Trichinella pseudospiralis. (1989) (4)
Plasmacytoid Dendritic Cells are the Primary Source of IFN-α During the Immunopathogenesis of Desiccating Stress-Induced Dry Eye Disease (2013) (4)
Induction of Anterior Chamber-Associated Immune Deviation Requires an Intact, Functional Spleen (2007) (4)
UVB irradiation renders corneal allografts tolerogenic for allospecific delayed hypersensitivity responses. (1993) (4)
Spontaneous Autoimmune Dacryoadenitis in Aged CD25KO (2009) (3)
IL-17–Dependent, IFN-γ–Independent Tumor Rejection Is Mediated by Cytotoxic T Lymphocytes and Occurs at Extraocular Sites, but Is Excluded from the Eye (2011) (3)
Transplantation of the B16-F10 melanoma to the anterior chamber of the eye uniquely fails to elicit elevation in plasma proteinase activity. (1986) (3)
Protective immunity against tetrathyridia of Mesocestoides corti (Cestoda): adoptive transfer by spleen cells. (1977) (3)
CD8 T Cells Circumvent Immune Privilege in the Eye and Mediate Intraocular Tumor Rejection by a TNF- -Dependent Mechanism (2007) (3)
Mouse model of brachytherapy in consort with enucleation for treatment of malignant intraocular melanoma. (1990) (3)
Plasmacytoid Dendritic Cells are Modulated During the Immunopathogenesis of Desiccating Stress-Induced Experimental Dry Eye (2012) (2)
Corneas Exposed to Desiccating Stress Are Immunogenic and Induce T Cell Proliferation in Mice With Experimental Lacrimal Keratoconjunctivitis (LKC) (2008) (2)
Innate and adaptive immune responses to ocular Acanthamoeba infections (2008) (2)
Uveal melanoma: a model for exploring fundamental cancer biology (2005) (2)
“Corneal Nerves, CD11c+ Dendritic Cells and Their Impact on Ocular Immune Privilege” (2021) (2)
Immunization of Rats Against Mesocestoides corti (Cestoda) by Subcutaneous Vaccination of Living Tetrathyridia and by Passive Transfer With Serum (1977) (2)
Mechanisms of Corneal Graft Rejection (2001) (2)
Comprar Immunology, inflammation and diseases of the eye | Darlene A. Dartt | 9780123819741 | Academic Press (2011) (2)
Why Does Acanthamoeba castellanii Not Progress Beyond the Cornea to Produce Intraocular Infections (2005) (1)
Desiccating Stress to the Ocular Surface Induces a Transferable T–Cell Mediated Lacrimal Keratoconjunctivitis (2006) (1)
Passing of a giant. (2004) (1)
Impact of the Host Microbiota on the Development of Murine Desiccating Stress-Induced Dry Eye Disease (2014) (1)
Luminex Analysis of Tears From a CD4+ T Cell Adoptively Transferred Mouse Model of Sjögren’s Syndrome-Like Lacrimal Keratoconjunctivitis (2008) (1)
Anterior Chamber-Associated Immune Deviation (ACAID) promotes corneal allograft survival (1996) (1)
Penetrating keratoplasty to one eye abolishes immune privilege and promotes corneal allograft rejection in the opposite eye, even to grafts from unrelated donors (2013) (1)
The Role of IFN– in the Pathophysiology of TH2 Inflammation in the Mouse Model of Allergic Conjunctivitis (2004) (1)
Liver NKT cells enhance, rather than inhibit, liver metastases arising from intraocular melanomas in mice (2014) (0)
Generation and Characterization of Chimeric Complement Factor H Transgenic Mice With an At-Risk Mutation for Age-Related Macular Degeneration (2008) (0)
The Role of Allergic Conjunctivitis in the Exacerbation of Corneal Allograft Rejection (2011) (0)
Role of CD147 in Experimental Autoimmune Anterior Uveitis (EAAU) (2014) (0)
Parasite Eccentricities (2015) (0)
Allergic Conjunctivitis Increases the Incidence and Tempo of Immune–Mediated Corneal Allograft Rejection (2005) (0)
Chapter-16 Role of the Innate Immune System in Corneal Transplantation (2013) (0)
Role of the Mannose-Induced Acanthamoeba Protein and Acanthamoeba Plasminogen Activator as Immunogen for Mitigating Acanthamoeba Keratitis (2007) (0)
Potential Regulatory T Cell Mechanisms Of Immune Suppression In A Mouse Model Of Dry Eye (2013) (0)
Baseline Delayed-Type Hypersensitivity and Desiccating Stress- Induced Dry Eye are Significantly Influenced by Thermoneutral Housing Temperature (2015) (0)
Liver natural killer T cells enhance, rather than inhibit, liver metastases arising from intraocular melanomas in mice. (P2087) (2013) (0)
Th2 Alloimmune Responses Allograft Rejection by Activating Th1 and Allergic Conjunctivitis Exacerbates Corneal (2010) (0)
Towards a Mouse Model of AMD: Chimeric Complement Factor H Molecules Carrying the Y402H Variants Are Functional in vivo (2009) (0)
Corneal Allograft Survival Requires Interplay Between T Regulatory Cells and Interleukin-17A (2010) (0)
In vitro Expanded CD4+CD25+FoxP3+ Regulatory T Cells Inhibit Ocular Surface Inflammation in a Mouse Model of Dry Eye (2007) (0)
Immunology of the ocular surface/corneal graft: What happens when immune vigilance goes awry? (2005) (0)
Second corneal allografts ablate T regulatory cells that are induced by first corneal allografts and produce a permanent loss of immune privilege in both eyes (2015) (0)
Mitigation of Acanthamoeba keratitis by Activated Macrophages (2006) (0)
Interleukin-17 Promotes Immune Privilege of Corneal Allografts (2010) (0)
Oral Immunization With Acanthamoeba Mannose–Binding Protein Provides Protection Against Amoebic Keratitis (2004) (0)
Expression and Function of IL-2 and IL-15 Receptors on Human Uveal Melanoma Cells (2003) (0)
Immunogenic Role of Dry Eye Corneas in Lymphocyte Proliferation and Effect of TGF-ß1 and T Regulatory Cells in Dry Eye Cornea-Induced Lymphoproliferation (2007) (0)
Corneal nerve ablation in one eye induces Langerhans cell infiltration into both eyes and abolishes immune privilege in both eyes (2017) (0)
Prevent Lysis by NK Cells Macrophage Migration-Inhibitory Factor to Human Uveal Melanoma Cells Produce (2000) (0)
Role of Antigen-presenting Cells within Conjunctiva-associated Lymphoid Tissue in the Induction of Ocular Allergy (2018) (0)
Rapid Corneal Allograft Rejection with TH2 Cell Involvement in a Model of Atopic Conjunctivitis (2005) (0)
Alterations in Corneal Nerve Fiber Density and Pain Markers during the Progression of Desiccating Stress-Induced Dry Eye Disease (2012) (0)
Role of Contact Lens Wear, Bacterial Flora, and a Mannose-Induced Protease in the Pathogenesis of Acanthamoeba Keratitis (2005) (0)
Ocular Surface Antigen Presenting Cells are Necessary for the Generation of Autoreactive T cells during Experimental Dry Eye (2011) (0)
Role of Interferon–Gamma in Intraocular Tumor Rejection (2006) (0)
Cytokine Requirement, Molecular Mechanisms, and Kinetics of CD4+CD25+ T Regulatory Cells in the Establishment of Corneal Immune Privilege (2011) (0)
Therapeutic manipulation of ocular antigen-presenting cells in corneal transplantation (2007) (0)
Polarized Th1 and Th17 Cells Derived From a Mouse Model of Dry Eye Induce Ocular Surface Disease (2010) (0)
Autoimmune Lacrimal Keratoconjunctivitis Autoreactive T Cell-Mediated Experimental Ocular Surface APCs Are Necessary for (2011) (0)
Concomitant suppression of delayed-type hypersensitivity and stimulation of cytotoxic T-lymphocyte responses to anterior chamber allografts (1984) (0)
RejectionIncidence and Tempo of Corneal Allograft Responses to Alloantigens and Increases the Cutting Edge: Atopy Promotes Th2 (2005) (0)
Penetrating Keratoplasty To One Eye Abolishes Immune Privilege For Corneal Allografts Placed Into The Other Eye (2012) (0)
Effect of cholesterol on the growth and virulence of Acanthamoeba castellanii (1996) (0)
CD4+ T Cells, IFN and Macrophages Play an Important Role in the Spontaneous Eradication of an Intraocular Tumor (2003) (0)
Therapeutic potential of regulatory T cells to suppress ocular surface inflammation (2009) (0)
factors from IRIS ciliary body (I/CB) cell cultures upregulate bcl-2 which prevents apoptosis of corneal endothelial cells (1997) (0)
Mechanisms of immune deviation (2016) (0)
Apoptosis and homeostasis in the eye (2011) (0)
Th2-Mediated Airway Hyperreactivity Exacerbates Corneal Allograft Rejection (2008) (0)
The Fas/FasL system is involved in, but not required for CD4+ T cell–mediated corneal allograft rejection. (2004) (0)
Allergic Conjunctivitis Exacerbates Corneal Allograft Rejection by Rendering Effector Cells Resistant to T Regulatory Cell-mediated Suppression (2012) (0)
AMD-Like Changes in Cfh Transgenic Mice: Can Antigen-Specific Immunity Enhance the Phenotype? (2010) (0)
Comprar Ocular periphery and disorders | Darlene A. Dartt | 9780123820426 | Academic Press (2011) (0)
Immunopathogenesis of intraocular tumor rejection (1992) (0)
Erratum: Susceptibility of corneas from in vitro binding and invasion by acanthamoeba castellani (Investigative Ophthalmology and Visual Science (January 1992)) (1992) (0)
Tracking RPE Transplants Labeled by Retroviral Gene Transfer with Green Fluorescent Protein (1999) (0)
IL-10 Immune Privilege through Their Production Chamber-Associated Immune Deviation and T Cells Promote Anterior δγ (2006) (0)
Penetrating keratoplasty to one eye abolishes immune privilege for corneal allograft placed into the other eye. (P2164) (2013) (0)
Transplantation of cultured human amniotic epithelial cells onto the ocular surface (1997) (0)
Deregulation of Acanthamoeba castellanii steroidogenesis is amoebicidal and protects cultured corneal cells from Ac attack (2019) (0)
Lymphoma Allograffs Abrogate Immune Privilege Within the Anterior Chamber of the Eye (2005) (0)
Immunology of Uveal Melanoma: Immuno suppressive Factors and the Basis for Immunotherapy (2003) (0)
Interferon-gamma is required for protecting against intraocular tumor growth after peripheral immunization but not for the generation of tumor-specific cytotoxic T-lymphocytes. (2015) (0)
Expression Of Adhesion Molecules During Development Of Conjunctiva-Associated Lymphoid Tissue (2012) (0)
Class I and II Antigen Presentation Chamber of the Eye: Role of B Cells in MHC Peripheral Tolerance Via the Anterior (2006) (0)
Fluorescent antibody studies of sera and intestinal extracts from mice subcutaneously vaccinated with tetrathyridia of Mesocestoides corti (Cestoda). (1978) (0)
Role of Fas-Induced Apoptosis in the Immune Rejection of Corneal Allografts (2002) (0)
Mice with Desiccating Stress-Induced Dry Eye Develop Trigeminal Neuralgia, Despite Decreased Corneal Sensitivity and Nerve Fiber Degeneration (2013) (0)
Protective immunity against Acanthahoeba keratitis in a Chinese hamster model (1996) (0)
Characterization of the Mannose-Stimulated Acanthamoeba Castellanii Cytolytic Protein (2003) (0)
Cornea Autoantibodies Contribute to the Immunopathogenesis of Experimental Dry Eye Disease (2012) (0)
TRAIL–induced apoptosis as a mechanism of ocular immune privilege (2004) (0)
Chapter-15 Atopy as a Risk Factor for Corneal Allograft Rejection (2010) (0)
Immunological analysis of orally induced tolerance to corneal alloantigens (1997) (0)
Role of TNF- and iNOS in CD4+ T Cell-Mediated Immune Responses That Reject Intraocular Tumors but Destroy the Eye (2010) (0)
Erratum: A pig model of acanthamoeba keratitis: Transmission via contaminated contact lenses (Investigative Ophthalmology and Visual Science (January 1992)) (1992) (0)
Inhibition of Uveal Melanoma Metastasis by Suppression of CXCR4 Expression (2009) (0)
IL-17 Neutralization Mutes Inflammation in a Mouse Model of Experimental Autoimmune Lacrimal Keratoconjunctivitis (2009) (0)
Inhibition Of Interferon- Promotes Survival Of MHC-mismatched Corneal Allografts But Exacerbates Rejection Of MHC Plus Minor Histocompatibility Antigen-mismatched Corneal Allografts (2012) (0)
Conjunctival antigen presenting cells: Sentinels for ocular surface inflammation (2011) (0)
Stress-Induced Damage to the Ocular Surface Resembling Dry Eye can Occur Independently of Chronic T cell-mediated Disease (2014) (0)
Characterization of Intraepithelial Lymphocyte Populations and Their Changes in Response to Experimental Desiccating Stress (2011) (0)
Ultrastructure and Function of Conjunctiva-Associated Lymphoid Tissue in a Novel Mouse Model (2009) (0)
Anterior Chamber of the Eye Cell-Dependent Tumor Rejection in the T + in CD 4 γ Role of TRAIL and IFN-Y (2003) (0)
The Effect of Corneas From Dry Eye Mice on Peripheral Lymphocyte Proliferation (2006) (0)
Acanthamoeba castellanii Secretes a Novel 133 Kd Cytolytic Protein When Stimulated With Methyl -D-Manno-Pyranoside (2002) (0)
Subject Index Vol. 144, 2007 (2007) (0)
CD4+CD25+ Regulatory T Cells Contribute to the Immune Privilege of Corneal Allografts (2008) (0)
ROLEOFTEAR ANTI-ACANTHAMOEBAIgA IN ACANTHAMOEBA KERATITIS (2002) (0)
Autoantibodies Contribute to the Immunopathogenesis of Dry Eye in a Mouse Model of Autoimmune Lacrimal Keratoconjunctivitis (2011) (0)
Anterior chember-associated immune deviation: clonal deletion or active suppression? abstr. (1981) (0)
Allergic Asthma Exacerbates Corneal Allograft Rejection Mediated by a Mixed Th1 and Th2 Alloimmune Response (2009) (0)
Susceptibilty of murine corneal kpithklial and endothelial cells to lysis by complement-dependent alloantibody (1997) (0)
Klk13 is a Putative Autoantigen During the Immunopathogenesis of Experimental Autoimmune Lacrimal Keratoconjunctivis (2009) (0)
Role of B Cells and T Cells in ACAID (2005) (0)
Disruption of TGF-β Signaling Improves Dry Eye Disease (2011) (0)
Effect of severing corneal nerves on the induction of immune tolerance during corneal transplantation (2016) (0)
Immunobiology of Uveal Melanoma (2010) (0)
Immunology of Uveitis (2016) (0)
Chapter-12 Innate Immune System and its Impact on Immune Privilege in the Eye (2013) (0)
Immunopathogenesis in a Mouse Model of Lacrimal Keratoconjunctivitis is Antigen Specific (2010) (0)
The Ocular Surface Plays an Antigenic Role in the Initiation of a Mouse Model of Dry Eye Disease (2008) (0)
Privilege and Corneal Graft Survival T Cells Are Needed for Ocular Immune (2001) (0)
Innate T Cells Are Necessary for Maximal Expression of Allergic Conjunctivitis (2010) (0)
Atopy and Th2‐biased immune responses exacerbate rather than promote corneal allograft survival (2008) (0)
PD-L1 Expression by Human Uveal Melanoma Inhibits T-Cell Function (2008) (0)
Anterior chamber associated immune deviation can be induced in mice by herpes simplex virus. Abstr. (1982) (0)
Cloning and Characterization of the Acanthamoeba Mannose-Induced Protein (2009) (0)
Immunology of the Eye (2016) (0)
Heterotopic corneal allografts induce cytotoxic T-lymphocytes but not delayed hypersensitivity responses in mice (1985) (0)
Gene therapy for preventing the metastasis of intraocular melanoma (1996) (0)
Regulatory T cell mediated suppression of dendritic cells in a mouse model of dry eye (2014) (0)
Acanthamoeba keratitis primes humoral but not cellular immune responses (1996) (0)
Phenotypic characterization of aqueous humor-mediated suppression of natural killer cell activity (1996) (0)
The Functional Role of B Cells in a Mouse Model of Autoimmune Lacrimal Keratoconjunctivitis: Adoptive Transfer of Serum, but Not B Cells Alone, Mediates Ocular Surface Inflammation (2010) (0)
Immune System and the Eye (2008) (0)
Non–Phthisical Rejection of Intraocular Tumors Does Not Require TRAIL–Mediated Apoptosis (2005) (0)
T Cell Subsets in the Immune Rejection of Murine Heterotopic Corneal Allogrofts (2005) (0)
Ocular Surface Immunity & Inflammation (2005) (0)
Anatomy and Pathology Epigenetic Regulation of CXCR 4 Expression by the Ocular Microenvironment (2013) (0)
CD8+ T Regulatory Cells Require IFN- to Mediate Anterior Chamber-Associated Immune Deviation (ACAID) Suppression (2011) (0)
Increased Incidence and Accelerated Corneal Allograft Rejection in Mice With Allergic Conjunctivitis Requires Both Th1 and Th2 Cells and the Th1 Cytokine, Interferon-Gamma (2007) (0)
Role Of Interferon- And IL-17 In The Immune Rejection Of Intraocular Tumors (2011) (0)
Cullen Symposium on Corneal and Ocular Surface Inflammation, 2005 (2005) (0)
Ultraviolet irradiated corneal allografts include antigen scientific unresponsiveness (1991) (0)
Expanded Mouse CD4+CD25+FoxP3+ Regulatory T Cells Maintain a Normal Phenotype in vitro (2007) (0)
Anterior chamber associated immune deviation requires a functional spleen. Abstr. (1981) (0)
Tumor Infiltrating CD8+ T Cells Mediate Non-Phthisical Intraocular Tumor Rejection by a TNF- Dependent Mechanism (2008) (0)
Contents Vol. 144, 2007 (2007) (0)
Expression of indoleamine dioxygenase (IDO) by uveal melanomas and ocular cells (2004) (0)
Immunopathology and Infectious Diseases Spontaneous Autoimmune Dacryoadenitis in Aged CD 25 KO Mice (2010) (0)
Aqueous humor and iris ciliary body cell culture supernatants upregulate BCL-2 and downregulate Bax gene expression and suppress apoptosis in corneal endothelial cells (1996) (0)
Effects of IFN and Cyclosporin A (CsA) on Tear Production in a Mouse Model of Keratoconjunctivitis Sicca (KCS) (2003) (0)
IFN-γ, a TH1-Type Cytokine, is Functionally Important in TH2 Ocular Surface Inflammation in the Mouse Model of Allergic Conjunctivitis (2005) (0)
The role of NKT cells in immune evasion of liver metastases arising from intraocular tumors (74.12) (2012) (0)
J. Wayne Streilein, MD (1935-2004) (2005) (0)
Defective FasL expression is associated with increased resistance to melanoma liver metastases and enhanced natural killer cell activity. (2019) (0)
The generation of regulatory t cells in an in vitro model of the acaid spleen (1997) (0)
Severing corneal nerves induces the release of substance P which converts ocular surface CD11c+ cells to contrasuppressor cells that abolish ocular immune privilege. (2018) (0)

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