Jerson Lima
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(Suggest an Edit or Addition)According to Wikipedia, Jerson Lima Silva , usually known as Jerson Lima, is a Brazilian biophysicist. He is known for his pioneering research in the field of structural biology, publishing important studies on protein folding and the relationship between protein aggregates and diseases such as cancer, prion diseases and Parkinson's disease.
Jerson Lima's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. (2005) (543)
- Pressure stability of proteins. (1993) (473)
- Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro (1994) (391)
- Pressure provides new insights into protein folding, dynamics and structure. (2001) (350)
- Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection (1992) (346)
- Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages (1995) (313)
- Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes (1996) (296)
- Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta) (1991) (286)
- Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells (1996) (255)
- Evidence of the presence of T helper type 17 cells in chronic lesions of human periodontal disease. (2009) (254)
- Cytokine pattern determines the progression of experimental periodontal disease induced by Actinobacillus actinomycetemcomitans through the modulation of MMPs, RANKL, and their physiological inhibitors. (2006) (224)
- DNA Converts Cellular Prion Protein into the β-Sheet Conformation and Inhibits Prion Peptide Aggregation* (2001) (206)
- Mutant p53 Aggregates into Prion-like Amyloid Oligomers and Fibrils (2012) (200)
- Cytosolic-free calcium elevation in Trypanosoma cruzi is required for cell invasion (1994) (200)
- IL-10 mediates susceptibility to Trypanosoma cruzi infection. (1994) (197)
- The preaggregated state of an amyloidogenic protein: hydrostatic pressure converts native transthyretin into the amyloidogenic state. (2000) (197)
- Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: tissue parasitism and endogenous IFN-gamma as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi. (2000) (192)
- Anti-CD4 abrogates rejection and reestablishes long-term tolerance to syngeneic newborn hearts grafted in mice chronically infected with Trypanosoma cruzi (1992) (162)
- Dissociation of amyloid fibrils of α-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities (2003) (160)
- Pressure dissociation and conformational drift of the beta dimer of tryptophan synthase. (1986) (159)
- Fibrillar aggregates of the tumor suppressor p53 core domain. (2003) (158)
- Modulation of chemokine production and inflammatory responses in interferon-gamma- and tumor necrosis factor-R1-deficient mice during Trypanosoma cruzi infection. (2001) (152)
- High-pressure chemical biology and biotechnology. (2014) (149)
- Prion-like aggregation of mutant p53 in cancer. (2014) (146)
- The dual role of p55 tumour necrosis factor‐α receptor in Actinobacillus actinomycetemcomitans‐induced experimental periodontitis: host protection and tissue destruction (2006) (144)
- Dissociation of a native dimer to a molten globule monomer. Effects of pressure and dilution on the association equilibrium of arc repressor. (1992) (132)
- The use of hydrostatic pressure as a tool to study viruses and other macromolecular assemblages. (1996) (130)
- Oleic acid modulation of the immune response in wound healing: a new approach for skin repair. (2011) (123)
- Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors. (2011) (111)
- Intriguing nucleic-acid-binding features of mammalian prion protein. (2008) (106)
- Saliva of Rhipicephalus sanguineus tick impairs T cell proliferation and IFN-gamma-induced macrophage microbicidal activity. (1998) (102)
- Nitric oxide-induced apoptotic cell death in the acute phase of Trypanosoma cruzi infection in mice. (1998) (102)
- Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins† (2009) (98)
- Arc repressor will not denature under pressure in the absence of water. (1994) (95)
- Hydration and packing effects on prion folding and beta-sheet conversion. High pressure spectroscopy and pressure perturbation calorimetry studies. (2004) (95)
- Differential expression of chemokines and chemokine receptors in inflammatory periapical diseases. (2005) (94)
- Effects of hydrostatic pressure on a membrane-enveloped virus: high immunogenicity of the pressure-inactivated virus (1992) (94)
- Low temperature and pressure stability of picornaviruses: implications for virus uncoating. (1999) (93)
- Leukotriene B4 Induces Nitric Oxide Synthesis in Trypanosoma cruzi-Infected Murine Macrophages and Mediates Resistance to Infection (2002) (86)
- LexA Repressor Forms Stable Dimers in Solution (2000) (86)
- New insights into the mechanisms of protein misfolding and aggregation in amyloidogenic diseases derived from pressure studies. (2004) (84)
- Hydrostatic pressure rescues native protein from aggregates. (1999) (84)
- Tumour necrosis factor‐alpha and leukotriene B4 mediate the neutrophil migration in immune inflammation (2001) (84)
- Prion Protein Complexed to N2a Cellular RNAs through Its N-terminal Domain Forms Aggregates and Is Toxic to Murine Neuroblastoma Cells*S⃞ (2008) (81)
- Molten-globule conformation of Arc repressor monomers determined by high-pressure 1H NMR spectroscopy. (1993) (79)
- The anti-Parkinsonian drug selegiline delays the nucleation phase of α-synuclein aggregation leading to the formation of nontoxic species. (2011) (78)
- The aggregation of mutant p53 produces prion-like properties in cancer (2014) (76)
- Human leukocyte antigen-G expression after kidney transplantation is associated with a reduced incidence of rejection. (2008) (76)
- Structural insights into the interaction between prion protein and nucleic acid. (2006) (75)
- Periodontitis and arthritis interaction in mice involves a shared hyper-inflammatory genotype and functional immunological interferences (2010) (74)
- Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species. (2005) (73)
- KM(+), a lectin from Artocarpus integrifolia, induces IL-12 p40 production by macrophages and switches from type 2 to type 1 cell-mediated immunity against Leishmania major antigens, resulting in BALB/c mice resistance to infection. (2001) (73)
- Pressure-induced dissociation of brome mosaic virus. (1988) (72)
- Cold denaturation of a repressor-operator complex: the role of entropy in protein-DNA recognition. (1994) (72)
- Anomalous pressure dissociation of large protein aggregates. Lack of concentration dependence and irreversibility at extreme degrees of dissociation of extracellular hemoglobin. (1989) (71)
- A hypothesis to reconcile the physical and chemical unfolding of proteins (2015) (70)
- Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer. (2018) (69)
- Involvement of NO in the failure of neutrophil migration in sepsis induced by Staphylococcus aureus (2002) (69)
- Interferon-gamma and tumor necrosis factor-alpha determine resistance to Paracoccidioides brasiliensis infection in mice. (2000) (68)
- Inactivation of simian immunodeficiency virus by hydrostatic pressure. (1995) (68)
- Expression of suppressors of cytokine signaling in diseased periodontal tissues: a stop signal for disease progression? (2006) (68)
- Mitochondrial damage as an early event of monensin-induced cell injury in cultured fibroblasts L929. (2005) (67)
- Hydration and packing are crucial to amyloidogenesis as revealed by pressure studies on transthyretin variants that either protect or worsen amyloid disease. (2003) (65)
- Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease? (2016) (64)
- The amino-terminal PrP domain is crucial to modulate prion misfolding and aggregation. (2005) (64)
- Experimental periodontitis in mice selected for maximal or minimal inflammatory reactions: increased inflammatory immune responsiveness drives increased alveolar bone loss without enhancing the control of periodontal infection. (2009) (61)
- Pressure denaturation of the bacteriophage P22 coat protein and its entropic stabilization in icosahedral shells. (1994) (60)
- Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor (2013) (60)
- High-pressure NMR study of the dissociation of Arc repressor. (1994) (57)
- Heparin binding by murine recombinant prion protein leads to transient aggregation and formation of RNA-resistant species. (2011) (56)
- Heparin binding confers prion stability and impairs its aggregation (2014) (56)
- Pressure-inactivated yellow fever 17DD virus: implications for vaccine development. (2008) (56)
- Structure of the Ebola Fusion Peptide in a Membrane-mimetic Environment and the Interaction with Lipid Rafts* (2007) (56)
- Cognate DNA stabilizes the tumor suppressor p53 and prevents misfolding and aggregation. (2009) (56)
- beta-Chemokines enhance parasite uptake and promote nitric oxide-dependent microbiostatic activity in murine inflammatory macrophages infected with Trypanosoma cruzi. (1999) (55)
- The p53 Core Domain Is a Molten Globule at Low pH (2009) (55)
- Inducible cyclooxygenase released prostaglandin mediates immunosuppression in acute phase of experimental Trypanosoma cruzi infection. (2005) (54)
- Modulation of Prion Protein Oligomerization, Aggregation, and β-sheet Conversion by 4,4′-Dianilino-1,1′-binaphthyl-5,5′-sulfonate (bis-ANS)* (2004) (54)
- Pressure-induced formation of inactive triple-shelled rotavirus particles is associated with changes in the spike protein Vp4. (2001) (54)
- Nonspecific prion protein-nucleic acid interactions lead to different aggregates and cytotoxic species. (2012) (54)
- The role of IL-12 in experimental Trypanosoma cruzi infection. (1998) (54)
- Partially folded states of the capsid protein of cowpea severe mosaic virus in the disassembly pathway. (1997) (53)
- Reversible aggregation plays a crucial role on the folding landscape of p53 core domain. (2004) (53)
- Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s disease (2019) (52)
- The “Jekyll and Hyde” Actions of Nucleic Acids on the Prion-like Aggregation of Proteins* (2016) (51)
- Modulation of mucosal immunity in a murine model of food‐induced intestinal inflammation (2007) (51)
- Folding of a pressure-denatured model protein. (1999) (50)
- Different degrees of cooperativity of the Ca2+-induced changes in fluorescence intensity of solubilized sarcoplasmic reticulum ATPase. (1981) (50)
- Nitric oxide is involved in the lesions of the peripheral autonomic neurons observed in the acute phase of experimental Trypanosoma cruzi infection. (1999) (49)
- Dopamine affects the stability, hydration, and packing of protofibrils and fibrils of the wild type and variants of alpha-synuclein. (2007) (48)
- Reversible pressure dissociation of R17 bacteriophage. The physical individuality of virus particles. (1993) (47)
- Resveratrol prevents p53 aggregation in vitro and in breast cancer cells (2018) (47)
- Cancer Chemoprevention by Resveratrol: The p53 Tumor Suppressor Protein as a Promising Molecular Target (2017) (47)
- Cold denaturation of an icosahedral virus. The role of entropy in virus assembly. (1995) (47)
- Pressure induces folding intermediates that are crucial for protein-DNA recognition and virus assembly. (2002) (47)
- Conversion of wild-type p53 core domain into a conformation that mimics a hot-spot mutant. (2003) (46)
- Protein folding and aggregation: two sides of the same coin in the condensation of proteins revealed by pressure studies. (2006) (46)
- Hydrostatic Pressure Induces the Fusion-active State of Enveloped Viruses* (2002) (45)
- Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex* (2016) (45)
- Tumor necrosis factor-alpha -308G/A single nucleotide polymorphism and red-complex periodontopathogens are independently associated with increased levels of tumor necrosis factor-alpha in diseased periodontal tissues. (2009) (45)
- Differences in pressure stability of the three components of cowpea mosaic virus: implications for virus assembly and disassembly. (1994) (44)
- Role of entropic interactions in viral capsids: single amino acid substitutions in P22 bacteriophage coat protein resulting in loss of capsid stability. (1995) (44)
- Aggregation tendencies in the p53 family are modulated by backbone hydrogen bonds (2016) (42)
- p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells (2019) (42)
- Induction of cell-mediated immunity during early stages of infection with intracellular protozoa. (1998) (41)
- Fourier transform infrared spectroscopy provides a fingerprint for the tetramer and for the aggregates of transthyretin. (2006) (40)
- DNA tightens the dimeric DNA-binding domain of human papillomavirus E2 protein without changes in volume. (2000) (40)
- Osmolytes protect mitochondrial F(0)F(1)-ATPase complex against pressure inactivation. (2001) (39)
- Effect of hydrostatic pressure on the mitochondrial ATP synthase. (1988) (38)
- Migration of vesicular stomatitis virus glycoprotein to the nucleus of infected cells. (1996) (38)
- Mimicry of the calcium-induced conformational state of troponin C by low temperature under pressure. (1996) (37)
- Pressure-inactivated FMDV: a potential vaccine. (2004) (37)
- Transient Transfection of a Wild-Type p53 Gene Triggers Resveratrol-Induced Apoptosis in Cancer Cells (2012) (37)
- Reassembly of a large multisubunit protein promoted by nonprotein factors. Effects of calcium and glycerol on the association of extracellular hemoglobin. (1991) (36)
- Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer (2015) (36)
- Liquid-liquid phase transitions and amyloid aggregation in proteins related to cancer and neurodegenerative diseases. (2019) (35)
- Oncogenic Gain of Function in Glioblastoma Is Linked to Mutant p53 Amyloid Oligomers (2020) (34)
- Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain (2017) (34)
- Activation of cytokines corroborate with development of inflammation and autoimmunity in thromboangiitis obliterans patients (2012) (34)
- The hypothesis of the catalytic action of nucleic acid on the conversion of prion protein. (2005) (33)
- Tetramerization of the LexA repressor in solution: implications for gene regulation of the E.coli SOS system at acidic pH. (2006) (33)
- Dentin Sialoprotein and Phosphoprotein Induce Neutrophil Recruitment: A Mechanism Dependent on IL-1β, TNF-α, and CXC Chemokines (2004) (33)
- Inhibition of Mayaro virus infection by bovine lactoferrin. (2014) (33)
- Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion. (2011) (32)
- The peculiar interaction between mammalian prion protein and RNA (2008) (32)
- Intermediate states of assembly in the dissociation of gastropod hemocyanin by hydrostatic pressure. (1994) (32)
- Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues (2020) (32)
- Self-association and modification of calcium binding in solubilized sarcoplasmic reticulum adenosinetriphosphatase. (1983) (32)
- Conformational changes in bovine lactoferrin induced by slow or fast temperature increases (2008) (31)
- Characterization of a Partially Folded Monomer of the DNA-binding Domain of Human Papillomavirus E2 Protein Obtained at High Pressure* (1998) (30)
- The Status of p53 Oligomeric and Aggregation States in Cancer (2020) (30)
- Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands† (2021) (30)
- PrP interactions with nucleic acids and glycosaminoglycans in function and disease. (2010) (30)
- Virus Maturation Targets the Protein Capsid to Concerted Disassembly and Unfolding* (2000) (29)
- Dissecting the role of protein–protein and protein–nucleic acid interactions in MS2 bacteriophage stability (2006) (29)
- Intensification of acute Trypanosoma cruzi myocarditis in BALB/c mice pretreated with low doses of cyclophosphamide or gamma irradiation. (1990) (29)
- Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer (2018) (28)
- Concentration dependence of the subunit association of oligomers and viruses and the modification of the latter by urea binding. (1996) (28)
- Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core (2016) (28)
- The role of RNA in mammalian prion protein conversion (2012) (28)
- Pathological implications of nucleic acid interactions with proteins associated with neurodegenerative diseases (2014) (27)
- Slab gel electrophoresis of oligomeric proteins under high hydrostatic pressure. I. Description of the system and demonstration of the pressure dissociation of a dimer. (1987) (27)
- Aggravation of both Trypanosoma cruzi and murine leukemia virus by concomitant infections. (1993) (27)
- The Metastable State of Nucleocapsids of Enveloped Viruses as Probed by High Hydrostatic Pressure* (2001) (27)
- On the entry of an emerging arbovirus into host cells: Mayaro virus takes the highway to the cytoplasm through fusion with early endosomes and caveolae-derived vesicles (2017) (25)
- Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s disease (2019) (25)
- Structure of a Membrane-binding Domain from a Non-enveloped Animal Virus (2006) (25)
- Dentin sialoprotein and phosphoprotein induce neutrophil recruitment: a mechanism dependent on IL-1beta, TNF-beta, and CXC chemokines. (2004) (24)
- Liquid‐liquid phase separation and fibrillation of the prion protein modulated by a high‐affinity DNA aptamer (2020) (24)
- High-pressure applications in medicine and pharmacology (2004) (24)
- Local heterogeneity in the pressure denaturation of the coiled-coil tropomyosin because of subdomain folding units. (2001) (24)
- Positive Contribution of Hydration on DNA Binding by E2c Protein from Papillomavirus* (2004) (24)
- Envelope Lipid-packing as a Critical Factor for the Biological Activity and Stability of Alphavirus Particles Isolated from Mammalian and Mosquito Cells* (2010) (24)
- Formation of a denatured dimer limits the thermal stability of Arc repressor. (1997) (24)
- Measuring the Strength of Interaction between the Ebola Fusion Peptide and Lipid Rafts: Implications for Membrane Fusion and Virus Infection (2011) (23)
- Reciprocal remodeling upon binding of the prion protein to its signaling partner hop/STIl (2009) (23)
- Pressure and low temperature effects on the fluorescence emission spectra and lifetimes of the photosynthetic components of cyanobacteria. (1992) (23)
- Cavity defects in the procapsid of bacteriophage P22 and the mechanism of capsid maturation. (1999) (22)
- VP4 protein from human rhinovirus 14 is released by pressure and locked in the capsid by the antiviral compound WIN. (2007) (21)
- Tumor necrosis factor-related apoptosis-inducing ligand mediates the resolution of allergic airway inflammation induced by chronic allergen inhalation (2014) (21)
- Monomer-dimer association constant of solubilized sarcoplasmic reticulum ATPase. (1985) (21)
- Protein-RNA Interactions and Virus Stability as Probed by the Dynamics of Tryptophan Side Chains* (2002) (21)
- Bioactive Compounds and Metabolites from Grapes and Red Wine in Breast Cancer Chemoprevention and Therapy (2020) (21)
- Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells (2019) (21)
- Role of hydration in the closed-to-open transition involved in Ca2+ binding by troponin C. (2003) (21)
- Pressure-temperature folding landscape in proteins involved in neurodegenerative diseases and cancer. (2013) (20)
- Distinct Roles of Th17 and Th1 Cells in Inflammatory Responses Associated with the Presentation of Paucibacillary Leprosy and Leprosy Reactions (2017) (20)
- Effects of hydrostatic pressure on the Leptospira interrogans: high immunogenicity of the pressure-inactivated serovar hardjo. (2001) (20)
- Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C (2017) (20)
- The Structural Dynamics of the Flavivirus Fusion Peptide–Membrane Interaction (2012) (20)
- RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction (2019) (19)
- Energy coupling between DNA binding and subunit association is responsible for the specificity of DNA‐Arc interaction (1993) (19)
- The adjuvant effect of jacalin on the mouse humoral immune response to trinitrophenyl and Trypanosoma cruzi. (1999) (19)
- Hydration, cavities and volume in protein folding, aggregation and amyloid assembly (2009) (19)
- Resveratrol, Curcumin and Piperine Alter Human Glyoxalase 1 in MCF-7 Breast Cancer Cells (2020) (19)
- Different urea stoichiometries between the dissociation and denaturation of tobacco mosaic virus as probed by hydrostatic pressure. (2008) (17)
- Intranasal Immunization with a Colloid-Formulated Bacterial Extract Induces an Acute Inflammatory Response in the Lungs and Elicits Specific Immune Responses (2004) (17)
- Moniliophthora perniciosa Necrosis- and Ethylene-Inducing Protein 2 (MpNep2) as a Metastable Dimer in Solution: Structural and Functional Implications (2012) (17)
- Mutations in the hydrophobic core and in the protein-RNA interface affect the packing and stability of icosahedral viruses. (2003) (16)
- Allosteric Transmission along a Loosely Structured Backbone Allows a Cardiac Troponin C Mutant to Function with Only One Ca2+ Ion* (2017) (16)
- Inactivation of classical swine fever virus: association of hydrostatic pressure and ultraviolet irradiation. (2003) (16)
- Polyclonal F(ab’)2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency (2021) (16)
- Pressure-induced fusogenic conformation of vesicular stomatitis virus glycoprotein. (2003) (16)
- The intrinsically disordered C terminus of troponin T binds to troponin C to modulate myocardial force generation (2019) (16)
- The fusogenic state of mayaro virus induced by low pH and by hydrostatic pressure (2007) (16)
- Effects of hydrostatic pressure on the stability and thermostability of poliovirus: a new method for vaccine preservation. (2009) (15)
- Virus stability and protein-nucleic acid interaction as studied by high-pressure effects on nodaviruses. (2004) (15)
- Recent Synthetic Approaches towards Small Molecule Reactivators of p53 (2020) (15)
- Intramolecular Dynamics within the N-Cap-SH3-SH2 Regulatory Unit of the c-Abl Tyrosine Kinase Reveal Targeting to the Cellular Membrane*♦ (2013) (15)
- The proapoptotic protein Smac/DIABLO dimer has the highest stability as measured by pressure and urea denaturation. (2008) (15)
- Modulation of p53 and prion protein aggregation by RNA. (2019) (15)
- Synthesis and anti-prion activity evaluation of aminoquinoline analogues. (2010) (15)
- Hydration and Packing Effects on Prion Folding and β-Sheet Conversion (2004) (14)
- Equine hyperimmune globulin raised against the SARS-CoV-2 spike glycoprotein has extremely high neutralizing titers (2020) (14)
- B Cell-Deficient Mice Display Enhanced Susceptibility to Paracoccidioides brasiliensis Infection (2013) (13)
- Free-energy linkage between folding and calcium binding in EF-hand proteins. (2008) (13)
- Increase in fatty acids and flotillins upon resveratrol treatment of human breast cancer cells (2019) (13)
- Fine modulation of the respiratory syncytial virus M2-1 protein quaternary structure by reversible zinc removal from its Cys(3)-His(1) motif. (2013) (12)
- Insights into the intramolecular coupling between the N- and C-domains of troponin C derived from high-pressure, fluorescence, nuclear magnetic resonance, and small-angle X-ray scattering studies. (2013) (12)
- Volume and energy folding landscape of prion protein revealed by pressure. (2005) (12)
- Effects of Naturally Occurring Polyols and Urea on Mitochondrial F0F1ATPase (2000) (11)
- Biophysical characterization of p53 core domain aggregates. (2019) (11)
- Enhanced prion protein stability coupled to DNA recognition and milieu acidification. (2009) (11)
- A Contribution of the Mitochondrial Adenosinetriphosphatase Inhibitor Protein to the Thermal Stability of the F0F1-ATPase Complex (1997) (11)
- Exploring the polymorphism, conformational dynamics and function of amyloidogenic peptides and proteins by temperature and pressure modulation. (2020) (11)
- Volume and free energy of folding for troponin C C-domain: linkage to ion binding and N-domain interaction. (2008) (11)
- Virus inactivation by anilinonaphthalene sulfonate compounds and comparison with other ligands. (2000) (11)
- Pressure effects on the interaction between natural inhibitor protein and mitochondrial F1-ATPase. (1998) (10)
- Full Inactivation of Human Influenza Virus by High Hydrostatic Pressure Preserves Virus Structure and Membrane Fusion While Conferring Protection to Mice against Infection (2013) (10)
- Immunolocalization and pathological alterations following Strongyloides venezuelensis infection in the lungs and the intestine of MHC class I or II deficient mice. (2008) (9)
- Structural studies of MS2 bacteriophage virus particle disassembly by nuclear magnetic resonance relaxation measurements. (2003) (9)
- Pro-Oxidant Effect of Resveratrol on Human Breast Cancer MCF-7 Cells is Associated with CK2 Inhibition (2021) (9)
- Effects of Pressure on Large Multimeric Proteins and Viruses (1993) (9)
- Intranasal Immunization with Pressure Inactivated Avian Influenza Elicits Cellular and Humoral Responses in Mice (2015) (9)
- The interplay between a GC-rich oligonucleotide and copper ions on prion protein conformational and phase transitions. (2021) (9)
- Permeability alteration of the sarcolemmal membrane, particularly at the site of macrophage contact, in experimental chronic Trypanosoma cruzi myocarditis in mice. (1990) (8)
- Evaluation of some organic compounds on bloodstream forms of Trypanosoma cruzi. (1992) (8)
- Natural killer cells and interleukin-12 in patients with advanced cervical cancer under neoadjuvant chemotherapy. (1996) (8)
- The push-and-pull hypothesis in protein unfolding, misfolding and aggregation. (2017) (8)
- Ca(2+) and Mg(2+) binding to weak sites of TnC C-domain induces exposure of a large hydrophobic surface that leads to loss of TnC from the thin filament. (2006) (8)
- Erratum to “Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors” [Int. J. Biochem. Cell Biol. 43 (1) (2011) 60–64] (2011) (8)
- Reduced immunologic cell performance as a prognostic parameter for advanced cervical cancer. (2000) (8)
- Potent neutralizing equine antibodies raised against recombinant SARS-CoV-2 spike protein for COVID-19 passive immunization therapy (2020) (8)
- Biophysical and morphological studies on the dual interaction of non-octarepeat prion protein peptides with copper and nucleic acids (2014) (7)
- Hematopoietic SCT modulates gut inflammation in experimental inflammatory bowel disease (2010) (7)
- Effects of Hydrostatic Pressure on Viruses (2008) (7)
- Structural insights into the stabilization of the human immunodeficiency virus type 1 capsid protein by the cyclophilin-binding domain and implications on the virus cycle. (2015) (6)
- Second-Generation RT-QuIC Assay for the Diagnosis of Creutzfeldt-Jakob Disease Patients in Brazil (2020) (6)
- Mice Vaccination with High Hydrostatic Pressure-Inactivated H3N8 Virus Protects Against Experimental Avian Flu (2012) (6)
- Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C virus core protein (2016) (6)
- B cells are involved in the modulation of pathogenic gut immune response in food‐allergic enteropathy (2008) (6)
- Nucleic acid actions on abnormal protein aggregation, phase transitions and phase separation. (2022) (5)
- Conformational selection, dynamic restriction and the hydrophobic effect coupled to stabilization of the BIR3 domain of the human X-linked inhibitor of apoptosis protein by the tetrapeptide AVPI. (2010) (5)
- Endothelin-1 receptors play a minor role in the protection against acute Trypanosoma cruzi infection in mice. (2007) (5)
- Pressure-Inactivated Virus: A Promising Alternative for Vaccine Production. (2015) (5)
- Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy† (2021) (5)
- Process intensification for the production of yellow fever virus‐like particles as potential recombinant vaccine antigen (2021) (5)
- A biophysical characterization of the interaction of a hepatitis C virus membranotropic peptide with micelles. (2016) (4)
- SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice (2023) (4)
- Antibody‐dependent cellular cytotoxicity in chronic human Chagas disease (1983) (4)
- Stability of different influenza subtypes: How can high hydrostatic pressure be a useful tool for vaccine development? (2017) (4)
- Resveratrol Modifies Lipid Composition of Two Cancer Cell Lines (2020) (4)
- Liquid-liquid phase separation and aggregation of the prion protein globular domain modulated by a high-affinity DNA aptamer (2019) (4)
- Yellow Fever Vaccine Protects Resistant and Susceptible Mice Against Zika Virus Infection (2019) (4)
- Rabbit PrP Is Partially Resistant to in vitro Aggregation Induced by Different Biological Cofactors (2021) (3)
- Green Tea (Camellia sinensis) Extract Induces p53-Mediated Cytotoxicity and Inhibits Migration of Breast Cancer Cells (2021) (3)
- Synergistic effect of curcumin, piperine and resveratrol in MCF-7 and MDA MB-231 breast cancer cells. (2020) (3)
- The drifted and molten-globule state of proteins dissociated by pressure (1993) (3)
- Chemokine profile during allogeneic heart transplant rejection. (1999) (3)
- Controlling β-Amyloid Oligomerization by the Use of Naphthalene Sulfonates (2005) (3)
- Unveiling the Role of the Integrated Endoplasmic Reticulum Stress Response in Leishmania Infection – Future Perspectives (2016) (3)
- In Vitro Prion Amplification Methodology for Inhibitor Screening. (2018) (3)
- p53 Aggregation and prionoid effect and the modulation of this process by PRIMA‐1 and its active metabolite, 2‐methylene‐3‐quinuclidinone hydrate (754.4) (2014) (3)
- High pressure studies on the misfolding and aggregation of p53 in cancer and of α-synuclein in Parkinson’s disease (2019) (3)
- Carbohydrates Protect Mitochondrial F0F1-ATPase Complex against Thermal Inactivation (2000) (2)
- Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum (2021) (2)
- Highlights of the 3rd International Conference on High Pressure Bioscience and Biotechnology. (2005) (2)
- Yellow fever vaccine protects mice against Zika virus infection (2021) (2)
- Protein of a thousand faces: The tumor-suppressive and oncogenic responses of p53 (2022) (2)
- Title Aggregation-primed molten globule conformers of the p 53 core domain provide potential tools for studying p 53 C aggregation in cancer (2018) (2)
- In vitro transfer of cellular immunity to synthetic peptides of HIV-1 to human lymphocytes with exogenous RNA. (1996) (2)
- Response to Radulescu and Brenig: Infectious nucleic acids in prion disease: halfway there (2009) (2)
- Chagas's disease: humoral and cellular immune response. (1980) (1)
- Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice (2022) (1)
- Anticancer Therapeutic Strategies Targeting p53 Aggregation (2022) (1)
- Evolutionary Role of Water-Accessible Cavities in Src Homology 2 (SH2) Domains. (2022) (1)
- Immunohistochemical and ultrastructural evaluation of gametes and embryos of goats infected with CAEV. (2010) (1)
- Structural Behavior of Cardiac Troponin C Variants Present in Cardiomyopathic Patients (2015) (1)
- Backbone resonance assignments of the human p73 DNA binding domain (2016) (1)
- The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer. (2022) (1)
- Science and technology to combat dengue virus. (2009) (1)
- Understanding the p53 Aggregation Process through its Activators Resveratrol and PRIMA‐1 (2015) (1)
- Cryo-EM to visualize the structural organization of viruses (2021) (1)
- c-Abl regulatory unit dynamics reveal protein localization 1 Intramolecular dynamics within the NCap-SH 3-SH 2 regulatory unit of the c-Abl tyrosine kinase reveal targeting to the cellular membrane (2013) (1)
- Figure S1 - Small angle X-ray scattering Data set for MpNep2 monomer and dimer (2013) (0)
- Resveratrol prevents p53 core domain aggregation (754.1) (2014) (0)
- THE ANTI-PARKINSONIAN DRUG SELEGILINE (R(-)-DEPRENYL) INHIBITS THE NUCLEATION PHASE OF a-SYNUCLEIN AGGREGATION. (2008) (0)
- Chemopreventive effects of resveratrol derivatives on breast cancer cells (1011.5) (2014) (0)
- Protein Structure and Biology (2013) (0)
- Resveratrol Induces Reactive Oxygen Species Production and Apoptosis in Breast Cancer Cells (2010) (0)
- Evaluation of the pathophysiological role of PrP:RNA interaction (2011) (0)
- Cellular insights into the role of resveratrol on p53 modulation (2011) (0)
- bLf-PrP interaction: the antiprion effect of bovine lactoferrin (2022) (0)
- Studies on the utilization of a thioaptamer for the rescue of p53 and its mutants (2011) (0)
- PRIMA-1 inhibits Y220C p53 amyloid aggregation and synergizes with cisplatin in hepatocellular carcinoma (2023) (0)
- The Effect of High Hydrostatic Pressure on α‐Synuclein Fibrils Probed by NMR (2015) (0)
- SARS-CoV-2 spike protein induces long-term TLR4-mediated synapse and cognitive loss recapitulating Post-COVID syndrome (2022) (0)
- Targeting the Prion-like Aggregation of α-synuclein in Parkinson's Disease and Mutant p53 in Cancer (2018) (0)
- Conformational stability of SARS-CoV-2 glycoprotein spike variants (2022) (0)
- Structure and Stability of Wildtype and F29W Mutant Forms of the N-Domain of Avian Troponin C Subjected to High Pressures (1999) (0)
- Pressure studies on protein folding, misfolding, protein-DNA interactions and amyloidogenesis (2002) (0)
- Direct involvement of RNA in mammalian prion protein aggregation : Involvement of RNA in rPrP aggregation (2018) (0)
- Abstract 4482: Osteopontin, p53 and PTEN isoforms expression patterns in endometrium carcinoma cell lines (2017) (0)
- Structural analysis of Ebola virus fusion peptides in SDS micelles by spectroscopy approaches (2003) (0)
- Correction: Measuring the Strength of Interaction between the Ebola Fusion Peptide and Lipid Rafts: Implications for Membrane Fusion and Virus Infection (2011) (0)
- Production of yellow fever VLPs by perfusion cultivation of stable recombinant HEK293 cells (2020) (0)
- Paper of the Weel J. Biol. Chem.-2013-Protein Structure and Folding-28346 (2015) (0)
- Uncovering the structural flexibility of SARS-CoV-2 glycoprotein spike variants (2022) (0)
- Biophysical and morphological studies on the dual interaction of non-octarepeat prion protein peptides with copper and nucleic acids (2014) (0)
- NMR Structure of Ebola fusion peptide in SDS micelles at pH 7 (2007) (0)
- Structural insights into the interaction between prion protein and heparin (2007) (0)
- COVID-19 and the Challenges of Chemotherapy: The Failure Case of Hydroxychloroquine in the Clinical Treatment of SARS-CoV-2 Infection (2021) (0)
- Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion (2022) (0)
- Green Tea Extract (Camellia sinensis) as a Potential Antitumoral Agent on Breast Cancer Cells (FS13-04-19). (2019) (0)
- Pressure Studies on Protein-Dna Interactions (1993) (0)
- Stabilization of Tyrosine Kinase c-Abl through Motions and a Membrane Tether♦ (2013) (0)
- Different urea stoichiometries between the dissociation and denaturation of tobacco mosaic virus as probed by hydrostatic pressure (2008) (0)
- Prion protein complexed to a DNA aptamer induce behavioral and synapse dysfunction in mice (2021) (0)
- Water Leakage Pathway Leads to Internal Hydration of the p53 Core Domain. (2022) (0)
- Isolation and Characterization of RNA Molecules Bound to Recombinant Mouse Prion Protein (2013) (0)
- Weak Domain Stability and Higher Ca 2+ Binding Affinity Contribute to Allostery between the D/E Linker and N-Helix of Cardiac Troponin C (2018) (0)
- Backbone resonance assignments of the human p73 DNA binding domain (2015) (0)
- Clinical and Biophysical Characterization of a Mutation in the N-Helix Region of Cardiac Troponin C: Evidence for an Allosteric Mechanism of Contractile Dysfunction (2018) (0)
- B Cell-Deficient Mice Display Enhanced Susceptibility to Paracoccidioides brasiliensis Infection (2013) (0)
- SARS-CoV-2 Spike protein alters microglial purinergic signaling (2023) (0)
- Figure S2 - HSQC spectrum for MpNep2 monomer and dimer (2013) (0)
- Immunogenicity analysis of sarscov2 viral particles inactivated with β-propiolactone or high hydrostatic pressure in vivo (2023) (0)
- Dynamic and Structural Allosteric Events between the D/E Linker and N-Domain of Cardiac Troponin C Reveal a Novel Mechanism for Cardiac Muscle Regulation (2019) (0)
- Slab Gel Electrophoresis Performed at High Hydrostatic Pressure: A New Approach for the Study of Oligomeric Proteins (1989) (0)
- Table S1 - Peptide match for MpNep2 monomer and dimer obtained by mass spectrometry (MS/MS) (2013) (0)
- 02.001-THE PROTECTIVE IMMUNITY TO PARACOCCIDIOIDES BRASILIENSIS ELICITED BY A TH2-INDUCING ANTIGENS FORMULATED IN MPL ADJUVANT (2005) (0)
- PNAS Plus Significance Statements (2015) (0)
- Structural Basis for Nucleic Acid Binding to the Prion Protein (2006) (0)
- Assembly of Toxic Amyloid Fibrils of p53 at Physiological Conditions: Is Tumor Mutant of p53 a Prionoid? (2011) (0)
- APPROACH FOR THE STUDY OF OLIGOmRIC PROTEINS (1989) (0)
- Prion protein complexed to RNA through the amino-terminal domain aggregates and is toxic to neuroblastoma cells (2007) (0)
- Pathological implications of nucleic acid interactions with proteins associated with neurodegenerative diseases (2014) (0)
- “Push and Pull” Hypothesis to Unify the Physical and Chemical Unfolding of Proteins (2015) (0)
- Immunosuppression by peritoneal BCG-induced granulomas in mice. (1990) (0)
- Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C (2017) (0)
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