Jerzy Adamski
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Computer Science
Jerzy Adamski's Degrees
- PhD Computer Science University of Warsaw
- Masters Computer Science University of Warsaw
- Bachelors Computer Science University of Warsaw
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(Suggest an Edit or Addition)Jerzy Adamski's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Human metabolic individuality in biomedical and pharmaceutical research (2011) (929)
- Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach (2013) (784)
- Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum (2008) (691)
- Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation (2013) (662)
- A genome-wide perspective of genetic variation in human metabolism (2010) (639)
- Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations (2009) (617)
- Novel biomarkers for pre-diabetes identified by metabolomics (2012) (587)
- Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting (2010) (544)
- Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts. (2015) (401)
- Differences between Human Plasma and Serum Metabolite Profiles (2011) (386)
- Genetic diagnosis of Mendelian disorders via RNA sequencing (2017) (385)
- The role of 17 beta-hydroxysteroid dehydrogenases (2004) (335)
- The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (2009) (333)
- Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers (2011) (325)
- Rapamycin extends murine lifespan but has limited effects on aging. (2013) (313)
- 17beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes. (1999) (304)
- The dynamic range of the human metabolome revealed by challenges (2012) (301)
- Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data (2011) (296)
- Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance (2013) (295)
- Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics (2012) (274)
- Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D. (2002) (271)
- Human serum metabolic profiles are age dependent (2012) (247)
- Metabolomics for clinical use and research in chronic kidney disease (2017) (218)
- Molecular cloning of a novel widely expressed human 80 kDa 17 beta-hydroxysteroid dehydrogenase IV. (1995) (217)
- Atlas of Circadian Metabolism Reveals System-wide Coordination and Communication between Clocks (2018) (208)
- Targeted Metabolomics Identifies Reliable and Stable Metabolites in Human Serum and Plasma Samples (2014) (197)
- Integrated view on 17beta-hydroxysteroid dehydrogenases (2009) (196)
- Introducing the German Mouse Clinic: open access platform for standardized phenotyping (2005) (192)
- 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: Protein structures, functions, and recent progress in inhibitor development (2011) (186)
- The effect of antisense inhibition of urokinase receptor in human squamous cell carcinoma on malignancy. (1994) (180)
- Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels (2015) (179)
- Gender-specific pathway differences in the human serum metabolome (2015) (178)
- Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits (2013) (177)
- Interlaboratory Reproducibility of a Targeted Metabolomics Platform for Analysis of Human Serum and Plasma. (2017) (173)
- Mining the Unknown: A Systems Approach to Metabolite Identification Combining Genetic and Metabolic Information (2012) (156)
- DNA Methylation of Lipid-Related Genes Affects Blood Lipid Levels (2015) (153)
- Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency. (1998) (153)
- Evidence Supporting a Key Role of Lp-PLA2-Generated Lysophosphatidylcholine in Human Atherosclerotic Plaque Inflammation (2012) (152)
- A reference map of potential determinants for the human serum metabolome (2020) (152)
- A guide to 17β-hydroxysteroid dehydrogenases (2001) (152)
- Phytoestrogens inhibit human 17β-hydroxysteroid dehydrogenase type 5 (2001) (148)
- Toll-like receptor heterodimer variants protect from childhood asthma. (2008) (146)
- A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population. (2016) (144)
- Childhood Obesity Is Associated with Changes in the Serum Metabolite Profile (2012) (140)
- Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. (2003) (134)
- Steroids in teleost fishes: A functional point of view (2015) (130)
- A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection (2011) (129)
- Determination of cDNA, gene structure and chromosomal localization of the novel human 17β‐hydroxysteroid dehydrogenase type 7 (1999) (125)
- Multifunctionality of human 17β-hydroxysteroid dehydrogenases (2006) (125)
- Gene structure and regulation of the murine epithelial calcium channels ECaC1 and 2. (2001) (124)
- Porcine 80-kDa Protein Reveals Intrinsic 17-Hydroxysteroid Dehydrogenase, Fatty Acyl-CoA-hydratase/Dehydrogenase, and Sterol Transfer Activities (*) (1996) (124)
- Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes. (2015) (122)
- Reliability of Serum Metabolite Concentrations over a 4-Month Period Using a Targeted Metabolomic Approach (2011) (122)
- Metabolic Profiling Reveals Distinct Variations Linked to Nicotine Consumption in Humans — First Results from the KORA Study (2008) (122)
- Vitamin D signaling is modulated on multiple levels in health and disease (2006) (120)
- Variation of serum metabolites related to habitual diet: a targeted metabolomic approach in EPIC-Potsdam (2013) (114)
- Peroxisomal bifunctional protein deficiency revisited: resolution of its true enzymatic and molecular basis. (1999) (113)
- Targeted metabolomics profiles are strongly correlated with nutritional patterns in women (2012) (112)
- Methanobactin reverses acute liver failure in a rat model of Wilson disease. (2016) (107)
- Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk. (2015) (107)
- Metabolites associate with kidney function decline and incident chronic kidney disease in the general population. (2013) (107)
- Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study (2013) (106)
- IKKα controls canonical TGFβ–SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells (2010) (105)
- Serum metabolite concentrations and decreased GFR in the general population. (2012) (104)
- Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies (2018) (104)
- Effect of Empagliflozin on the Metabolic Signature of Patients With Type 2 Diabetes Mellitus and Cardiovascular Disease. (2017) (103)
- Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes (2015) (103)
- Mouse phenotyping. (2011) (103)
- Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study (2018) (103)
- Zebrafish and steroids: What do we know and what do we need to know? (2013) (100)
- Discovery of phosphatidylcholines and sphingomyelins as biomarkers for ovarian endometriosis. (2012) (99)
- Body Fat Free Mass Is Associated with the Serum Metabolite Profile in a Population-Based Study (2012) (98)
- Amino acids, lipid metabolites, and ferritin as potential mediators linking red meat consumption to type 2 diabetes. (2015) (97)
- Molecular cloning and amino acid sequence of the porcine 17β‐estradiol dehydrogenase (1994) (95)
- Targeted Metabolomics of Dried Blood Spot Extracts (2013) (94)
- Metabolite Profiling and Cardiovascular Event RiskCLINICAL PERSPECTIVE (2015) (94)
- Metabolomics platforms for genome wide association studies--linking the genome to the metabolome. (2013) (93)
- Linking diet, physical activity, cardiorespiratory fitness and obesity to serum metabolite networks: findings from a population-based study (2014) (93)
- Long-Term Stability of Human Plasma Metabolites during Storage at -80 °C. (2018) (92)
- Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism. (2002) (92)
- Unique multifunctional HSD17B4 gene product: 17beta-hydroxysteroid dehydrogenase 4 and D-3-hydroxyacyl-coenzyme A dehydrogenase/hydratase involved in Zellweger syndrome. (1999) (87)
- Requirement of the RNA-editing Enzyme ADAR2 for Normal Physiology in Mice* (2011) (87)
- Questionnaire-based self-reported nutrition habits associate with serum metabolism as revealed by quantitative targeted metabolomics (2011) (87)
- Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. (2016) (87)
- Systemic first-line phenotyping. (2009) (86)
- Androgen metabolism via 17beta-hydroxysteroid dehydrogenase type 3 in mammalian and non-mammalian vertebrates: comparison of the human and the zebrafish enzyme. (2005) (85)
- Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. (2007) (83)
- Comprehensive metabolic profiling of chronic low-grade inflammation among generally healthy individuals (2017) (83)
- Purification and properties of oestradiol 17 beta-dehydrogenase extracted from cytoplasmic vesicles of porcine endometrial cells. (1992) (81)
- Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques (2018) (81)
- The Human Blood Metabolome-Transcriptome Interface (2015) (81)
- Pre-Analytical Sample Quality: Metabolite Ratios as an Intrinsic Marker for Prolonged Room Temperature Exposure of Serum Samples (2015) (81)
- Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice (2018) (79)
- APOA5 variants and metabolic syndrome in Caucasianss⃞s⃞ The online version of this article (available at http://www.jlr.org) contains supplementary data in the form of three tables, one figure. Published, JLR Papers in Press, September 3, 2007. (2007) (78)
- Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis. (2018) (78)
- Serum and plasma amino acids as markers of prediabetes, insulin resistance, and incident diabetes (2018) (78)
- Association of Atopic Dermatitis with Cardiovascular Risk Factors and Diseases. (2017) (76)
- Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma (2013) (75)
- A novel 17beta-hydroxysteroid dehydrogenase in the fungus Cochliobolus lunatus: new insights into the evolution of steroid-hormone signalling. (1999) (69)
- Changes in the serum metabolite profile in obese children with weight loss (2014) (69)
- Testosterone Increases Susceptibility to Amebic Liver Abscess in Mice and Mediates Inhibition of IFNγ Secretion in Natural Killer T Cells (2013) (69)
- Cytochrome c oxidase subunit 4 isoform 2‐knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology (2012) (68)
- Identification and characterization of 17β-hydroxysteroid dehydrogenases in the zebrafish, Danio rerio (2004) (66)
- Genome-wide association studies with metabolomics (2012) (65)
- Random Survival Forest in practice: a method for modelling complex metabolomics data in time to event analysis. (2016) (65)
- Long term conservation of human metabolic phenotypes and link to heritability (2014) (65)
- Mutation analysis of congenital cataracts in Indian families: identification of SNPS and a new causative allele in CRYBB2 gene. (2004) (64)
- The sequence of porcine 80 kDa 17β-estradiol dehydrogenase reveals similarities to the short chain alcohol dehydrogenase family, to actin binding motifs and to sterol carrier protein (1994) (64)
- Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms (2016) (63)
- Preservation of Metabolic Flexibility in Skeletal Muscle by a Combined Use of n-3 PUFA and Rosiglitazone in Dietary Obese Mice (2012) (63)
- High-throughput extraction and quantification method for targeted metabolomics in murine tissues (2017) (63)
- Evaluation of various biomarkers as potential mediators of the association between coffee consumption and incident type 2 diabetes in the EPIC-Potsdam Study. (2014) (62)
- Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus (2002) (61)
- Characterization of Human DHRS6, an Orphan Short Chain Dehydrogenase/Reductase Enzyme (2006) (61)
- Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts (2017) (61)
- Identification of Serum Metabolites Associated With Incident Hypertension in the European Prospective Investigation Into Cancer and Nutrition–Potsdam Study (2016) (61)
- Molecular characterization of mouse 17β-hydroxysteroid dehydrogenase IV (1995) (60)
- Metabolomics approach reveals effects of antihypertensives and lipid-lowering drugs on the human metabolism (2014) (59)
- Local estradiol metabolism in osteoblast- and osteoclast-like cells (1997) (59)
- The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models. (2009) (59)
- Identification of biomarkers for apoptosis in cancer cell lines using metabolomics: tools for individualized medicine (2013) (59)
- Molecular basis of d-bifunctional protein deficiency (2001) (59)
- Isolation and embryonic expression of the novel mouse gene Hic1, the homologue of HIC1, a candidate gene for the Miller-Dieker syndrome. (1999) (57)
- Removing the bottlenecks of cell culture metabolomics: fast normalization procedure, correlation of metabolites to cell number, and impact of the cell harvesting method (2016) (57)
- Down-regulation by nuclear factor kappaB of human 25-hydroxyvitamin D3 1alpha-hydroxylase promoter. (2004) (57)
- Variation in the human lipidome associated with coffee consumption as revealed by quantitative targeted metabolomics. (2009) (57)
- The Saliva Metabolome in Association to Oral Health Status (2019) (55)
- 17β-hydroxysteroid dehydrogenase type 7 — an ancient 3-ketosteroid reductase of cholesterogenesis (2001) (55)
- HSD17B4 overexpression, an independent biomarker of poor patient outcome in prostate cancer (2009) (54)
- Evolution of 17β-HSD type 4, a multifunctional protein of β-oxidation (2001) (54)
- Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p. (2000) (54)
- Recent advances in 17beta-hydroxysteroid dehydrogenases (2009) (53)
- TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants. (2009) (53)
- Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer Development In Vivo. (2018) (53)
- In search for function of two human orphan SDR enzymes: Hydroxysteroid dehydrogenase like 2 (HSDL2) and short-chain dehydrogenase/reductase-orphan (SDR-O) (2009) (53)
- A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies. (2013) (53)
- International Ring Trial of a High Resolution Targeted Metabolomics and Lipidomics Platform for Serum and Plasma Analysis. (2019) (52)
- Zebrafish 17beta-hydroxysteroid dehydrogenases: An evolutionary perspective (2009) (51)
- Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis. (2016) (50)
- Changing Metabolic Signatures of Amino Acids and Lipids During the Prediabetic Period in a Pig Model With Impaired Incretin Function and Reduced β-Cell Mass (2012) (50)
- Altered levels of acylcarnitines, phosphatidylcholines, and sphingomyelins in peritoneal fluid from ovarian endometriosis patients (2016) (49)
- Metabolic Signatures of Cultured Human Adipocytes from Metabolically Healthy versus Unhealthy Obese Individuals (2014) (49)
- Srgap3–/– mice present a neurodevelopmental disorder with schizophrenia‐related intermediate phenotypes (2012) (47)
- The organelles containing porcine 17 beta-estradiol dehydrogenase are peroxisomes. (1995) (47)
- Structure-based design, synthesis and in vitro characterization of potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone. (2009) (45)
- Metabolite profiling reveals new insights into the regulation of serum urate in humans (2013) (44)
- Zebrafish 20β-Hydroxysteroid Dehydrogenase Type 2 Is Important for Glucocorticoid Catabolism in Stress Response (2013) (44)
- Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice. (2019) (44)
- Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues (2016) (44)
- Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism. (2013) (43)
- Stability of targeted metabolite profiles of urine samples under different storage conditions (2016) (42)
- Flavonoids and cinnamic acid derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (2009) (42)
- Inhibition of 17beta-hydroxysteroid dehydrogenases by phytoestrogens: Comparison with other steroid metabolizing enzymes (2005) (42)
- Steroid metabolism in cnidarians: Insights from Nematostella vectensis (2009) (42)
- Molecular characterization of Patched‐associated rhabdomyosarcoma (2003) (41)
- Metabolomics meets machine learning: Longitudinal metabolite profiling in serum of normal versus overconditioned cows and pathway analysis. (2019) (41)
- Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts (2020) (40)
- Perspectives in Understanding the Role of Human 17β‐Hydroxysteroid Dehydrogenases in Health and Disease (2009) (40)
- An IgE-associated polymorphism in STAT6 alters NF-kappaB binding, STAT6 promoter activity, and mRNA expression. (2009) (40)
- High Mobility Group N Proteins Modulate the Fidelity of the Cellular Transcriptional Profile in a Tissue- and Variant-specific Manner* (2013) (40)
- Interaction of the MAGUK family member Acvrinp1 and the cytoplasmic domain of the Notch ligand Delta1. (2003) (40)
- The exceptional sensitivity of brain mitochondria to copper. (2018) (40)
- Release of lysophospholipid ‘find-me’ signals during apoptosis requires the ATP-binding cassette transporter A1 (2012) (40)
- Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis (2016) (40)
- BEMER Electromagnetic Field Therapy Reduces Cancer Cell Radioresistance by Enhanced ROS Formation and Induced DNA Damage (2016) (40)
- A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. (2011) (40)
- Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives (2017) (40)
- Cholesterol metabolism promotes B‐cell positioning during immune pathogenesis of chronic obstructive pulmonary disease (2018) (40)
- Innovations in phenotyping of mouse models in the German Mouse Clinic (2012) (39)
- Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington’s disease peripheral blood samples (2016) (38)
- Cross-omics analysis revealed gut microbiome-related metabolic pathways underlying atherosclerosis development after antibiotics treatment (2020) (38)
- Characterization of the HSD17B4 gene: d-specific multifunctional protein 2/17β-hydroxysteroid dehydrogenase IV (1999) (37)
- Introduction of an electron withdrawing group on the hydroxyphenylnaphthol scaffold improves the potency of 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) inhibitors. (2011) (37)
- Novel estrogen-related genes and potential biomarkers of ovarian endometriosis identified by differential expression analysis (2011) (37)
- The Hydroxysteroid (17β) Dehydrogenase Family Gene HSD17B12 Is Involved in the Prostaglandin Synthesis Pathway, the Ovarian Function, and Regulation of Fertility. (2016) (37)
- Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum (2013) (36)
- Plasma and Serum Metabolite Association Networks: Comparability within and between Studies Using NMR and MS Profiling (2017) (36)
- Structure of the gene for the human 17β-hydroxysteroid dehydrogenase type IV (1998) (36)
- Expression of Different 17β-Hydroxysteroid Dehydrogenase Types and Their Activities in Human Prostate Cancer Cells. (1997) (36)
- Expression analysis of estrogen-metabolizing enzymes in human endometrial cancer (2006) (36)
- A single night of sleep curtailment increases plasma acylcarnitines: Novel insights in the relationship between sleep and insulin resistance. (2016) (36)
- Discovery of a novel enzyme mediating glucocorticoid catabolism in fish: 20beta-Hydroxysteroid dehydrogenase type 2 (2012) (36)
- Heart-Specific Knockout of the Mitochondrial Thioredoxin Reductase (Txnrd2) Induces Metabolic and Contractile Dysfunction in the Aging Myocardium (2015) (35)
- Identification of chemically diverse, novel inhibitors of 17β-hydroxysteroid dehydrogenase type 3 and 5 by pharmacophore-based virtual screening (2011) (35)
- High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice (2014) (35)
- A challenge for medicinal chemistry by the 17β-hydroxysteroid dehydrogenase superfamily: an integrated biological function and inhibition study. (2013) (34)
- Bayesian independent component analysis recovers pathway signatures from blood metabolomics data. (2012) (34)
- Transcriptional regulation of human and murine 17beta-hydroxysteroid dehydrogenase type-7 confers its participation in cholesterol biosynthesis. (2006) (34)
- Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice (2016) (34)
- Genetic associations with lipoprotein subfractions provide information on their biological nature. (2012) (34)
- Metabolomics screening identifies reduced L-carnitine to be associated with progressive emphysema. (2016) (34)
- Inhibitory effects of fluorine-substituted estrogens on the activity of 17beta-hydroxysteroid dehydrogenases (2006) (34)
- Multifunctionality of human 17beta-hydroxysteroid dehydrogenases. (2006) (33)
- The Munich MIDY Pig Biobank – A unique resource for studying organ crosstalk in diabetes (2017) (33)
- Metabolic signatures in apoptotic human cancer cell lines. (2011) (33)
- The tissue distribution of porcine 17β-estradiol dehydrogenase and its induction by progesterone (1995) (33)
- Metabolomic profiles in individuals with negative affectivity and social inhibition: A population-based study of Type D personality (2013) (33)
- Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers (2017) (33)
- Structure-based phylogenetic analysis of short-chain alcohol dehydrogenases and reclassification of the 17beta-hydroxysteroid dehydrogenase family. (2001) (32)
- Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up (2014) (32)
- Characterization of 17 beta-hydroxysteroid dehydrogenase IV. (1996) (32)
- Pharmacokinetics of metformin in patients with gastrointestinal intolerance (2018) (32)
- 5′ flanking sequence of the human immediate early responsive gene ccn1 (cyr61) and mapping of polymorphic CA repeat sequence motifs in the human ccn1 (cyr61) locus (2001) (32)
- Models including plasma levels of sphingomyelins and phosphatidylcholines as diagnostic and prognostic biomarkers of endometrial cancer (2018) (31)
- Circulating glutamate concentration as a biomarker of visceral obesity and associated metabolic alterations (2018) (31)
- Rational design of novel mutants of fungal 17beta-hydroxysteroid dehydrogenase. (2007) (31)
- Retinal proteome alterations in a mouse model of type 2 diabetes (2013) (30)
- Cardiovascular Risk Factors Associated With Blood Metabolite Concentrations and Their Alterations During a 4-Year Period in a Population-Based Cohort (2016) (30)
- Identification of a Potential Biomarker for FABP4 Inhibition: The Power of Lipidomics in Preclinical Drug Testing (2011) (30)
- Metabolomics of Ramadan fasting: an opportunity for the controlled study of physiological responses to food intake (2014) (30)
- Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses. (2014) (30)
- Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study (2017) (29)
- Peroxisome targeting of porcine 17β‐hydroxysteroid dehydrogenase type IV/D‐specific multifunctional protein 2 is mediated by its C‐terminal tripeptide AKI (1999) (29)
- A guide to 17beta-hydroxysteroid dehydrogenases. (2001) (29)
- Ageing Investigation Using Two-Time-Point Metabolomics Data from KORA and CARLA Studies (2019) (29)
- 17β-Hydroxysteroid Dehydrogenase from Cochliobolus lunatus: Model Structure and Substrate Specificity (2000) (29)
- Key elements of metabolomics in the study of biomarkers of diabetes (2016) (28)
- Empagliflozin improves left ventricular diastolic function of db/db mice. (2020) (28)
- Cord Blood Lysophosphatidylcholine 16: 1 is Positively Associated with Birth Weight (2018) (28)
- Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma (2013) (28)
- Metabolomics reveals determinants of weight loss during lifestyle intervention in obese children (2013) (27)
- Plasma Metabolomics Reveal Alterations of Sphingo- and Glycerophospholipid Levels in Non-Diabetic Carriers of the Transcription Factor 7-Like 2 Polymorphism rs7903146 (2013) (27)
- Characterization of the human and mouse ETV1/ER81 transcription factor genes: role of the two alternatively spliced isoforms in the human (1999) (27)
- Type 2 diabetes is associated with postprandial amino acid measures. (2016) (27)
- Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation (2018) (26)
- Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders (2016) (26)
- HLX1 gene variants influence the development of childhood asthma. (2009) (26)
- IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4 (2006) (26)
- Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice (2017) (26)
- Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium (2019) (26)
- Important roles of the AKR1C2 and SRD5A1 enzymes in progesterone metabolism in endometrial cancer model cell lines. (2015) (26)
- 12-months metabolic changes among gender dysphoric individuals under cross-sex hormone treatment: a targeted metabolomics study (2016) (26)
- Expression and regulation of aromatase and 17β-hydroxysteroid dehydrogenase type 4 in human THP 1 leukemia cells (1995) (25)
- Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus (2019) (25)
- Circadian expression of steroidogenic cytochromes P450 in the mouse adrenal gland – involvement of cAMP‐responsive element modulator in epigenetic regulation of Cyp17a1 (2012) (25)
- Associations between thyroid hormones and serum metabolite profiles in an euthyroid population (2013) (25)
- House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions (2018) (25)
- Endocrinology Meets Metabolomics: Achievements, Pitfalls, and Challenges (2017) (25)
- IKK&agr; controls canonical TGF&bgr;–SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells (2013) (24)
- Mitochondrial Regulation of the 26S Proteasome. (2020) (24)
- Embryonic expression of cholesterogenic genes is restricted to distinct domains and colocalizes with apoptotic regions in mice. (2003) (24)
- Species Used for Drug Testing Reveal Different Inhibition Susceptibility for 17beta-Hydroxysteroid Dehydrogenase Type 1 (2010) (24)
- RDH12, a retinol dehydrogenase causing Leber's congenital amaurosis, is also involved in steroid metabolism (2007) (24)
- Short-term glucocorticoid treatment increases insulin secretion in islets derived from lean mice through multiple pathways and mechanisms (2009) (24)
- Changes in metabolite profiles caused by genetically determined obesity in mice (2013) (23)
- Nonadditive Effects of Genes in Human Metabolomics (2015) (23)
- Expression of 17β-hydroxysteroid dehydrogenases in mesophilic and extremophilic yeast (2001) (23)
- Human 17beta-hydroxysteroid dehydrogenase type 5 is inhibited by dietary flavonoids. (2002) (23)
- Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study (2022) (22)
- IKKα controls canonical TGFβ-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells (2011) (22)
- Stiff-man syndrome: identification of 17β-hydroxysteroid dehydrogenase type 4 as a novel 80-kDa antineuronal antigen (2002) (22)
- Systemic Regulation of Host Energy and Oogenesis by Microbiome-Derived Mitochondrial Coenzymes. (2021) (22)
- Assignment of Human 17β-Hydroxysteroid Dehydrogenase IV to Chromosome 5q2 by Fluorescencein SituHybridization (1996) (22)
- Bioinformatic identification and characterization of new members of short-chain dehydrogenase/reductase superfamily (2006) (22)
- Absence of 11-keto reduction of cortisone and 11-ketotestosterone in the model organism zebrafish. (2017) (21)
- Cross-Laboratory Standardization of Preclinical Lipidomics Using Differential Mobility Spectrometry and Multiple Reaction Monitoring (2021) (21)
- Significance of individual amino acid residues for coenzyme and substrate specificity of 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus. (2003) (21)
- Potential Use of Gluconate in Cancer Therapy (2019) (21)
- LysoPC-acyl C16:0 is associated with brown adipose tissue activity in men (2017) (21)
- Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample (2017) (21)
- Low-parachor solvents extraction and thermostated micro-thin-layer chromatography separation for fast screening and classification of spirulina from pharmaceutical formulations and food samples. (2011) (21)
- Searching for the physiological function of 17β-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus: studies of substrate specificity and expression analysis (2001) (20)
- Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele (2014) (20)
- Pleiotropic Functions for Transcription Factor Zscan10 (2014) (20)
- Metabolic Fingerprints of Circulating IGF-1 and the IGF-1/IGFBP-3 Ratio: A Multifluid Metabolomics Study. (2016) (20)
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- Associations between adipose tissue volume and small molecules in plasma and urine among asymptomatic subjects from the general population (2020) (9)
- The Pathologic Effect of a Novel Neomorphic Fgf9Y162C Allele Is Restricted to Decreased Vision and Retarded Lens Growth (2011) (9)
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- Paramount importance of sample quality in pre-clinical and clinical research—Need for standard operating procedures (SOPs) (2019) (5)
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- Correlation guided Network Integration (CoNI) reveals novel genetic regulators of hepatic metabolism (2020) (2)
- Potential involvement of extracellular citrate in brain tumor progression. (2021) (2)
- Targeted assessment of the metabolome in skeletal muscle and in serum of dairy cows supplemented with conjugated linoleic acid during early lactation. (2021) (2)
- The search for predictive metabolic biomarkers for incident T2DM (2018) (2)
- Pre- versus post-operative untargeted plasma nuclear magnetic resonance spectroscopy metabolomics of pheochromocytoma and paraganglioma (2021) (2)
- Fecal Bile Acids and Neutral Sterols Are Associated with Latent Microbial Subgroups in the Human Gut (2022) (2)
- Metabolic signature associated with parameters of the complete blood count in apparently healthy individuals (2019) (2)
- Associations between usual food intake and fecal sterols and bile acids: results from the KORA FF4 study. (2019) (2)
- Expression of Different 17b-Hydroxysteroid Dehydrogenase Types and Their Activities in Human Prostate Cancer Cells* (1997) (2)
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- Integration of steroid research: Perspectives on environment factors, homeostasis in health, and disease treatment (2011) (1)
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- 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus: structural and functional aspects. (2001) (1)
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- Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids (2014) (1)
- Clinical studies in CKD (2012) (1)
- Skeletal Muscle Metabolomics for Metabolic Phenotyping and Biomarker Discovery (2019) (1)
- Network based conditional genome wide association analysis of human metabolomics (2016) (1)
- A reference map of potential determinants for the human serum metabolome (2020) (1)
- pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms (2017) (1)
- Pre-receptor steroid metabolism as target for pharmacological treatment (2009) (1)
- Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma (2013) (1)
- Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1 (2023) (1)
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- Human serum metabolic profiles are age dependent: Metabolic profiles associated with age (2012) (1)
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- Transcription factor binding site analysis. (2015) (1)
- Metabolomics of Ramadan fasting: an opportunity for the controlled study of physiological responses to food intake (2014) (1)
- Circulating steroid levels as correlates of adipose tissue phenotype in premenopausal women (2018) (1)
- Lab methods / biomarkers (2013) (1)
- Metabolomic profiling of the lung in a murine model of emphysema (2014) (1)
- Levels of Atg5 determine pancreatic tumor formation and metastasis in mice (2018) (1)
- Stability of targeted metabolite profiles of urine samples under different storage conditions (2016) (1)
- Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts (2023) (1)
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- Cinnamon: does it hold its promises in cows? Using non-targeted blood serum metabolomics profiling to test the effects of feeding cinnamon to dairy cows undergoing lactation-induced insulin resistance (2017) (0)
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- Down-regulation by secreted frizzled related protein 4 (sFRP4) of human 25-hydroxyvitamin D3 1alpha-hydroxylase promoter activity (2005) (0)
- Metabolite profiling reveals new insights into the regulation of serum urate in humans (2013) (0)
- Response to Comment on Adam et al. Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues. Diabetes 2016;65:3776–3785 (2017) (0)
- Sex-specific metabolic profiles of androgens and its main binding protein SHBG in a middle aged population without diabetes (2017) (0)
- Metabolomics reveals determinants of weight loss during lifestyle intervention in obese children (2013) (0)
- Machine learning approaches revealed metabolic signatures of incident chronic kidney disease in persons with pre-and type 2 diabetes (2020) (0)
- Thank you to all of our reviewers in 2020 (2021) (0)
- Gender-specific pathway differences in the human serum metabolome (2015) (0)
- SUN-LB97 Targeted Metabolomics as a Screening Tool in the Diagnosis of Endocrine Hypertension (2020) (0)
- Associations between adipose tissue volume and small molecules in plasma and urine among asymptomatic subjects from the general population (2020) (0)
- Metabolic footprint of the GLP-1 receptor agonist liraglutide in adolescent transgenic pigs with impaired incretin function (2014) (0)
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- Associations between thyroid hormones and serum metabolite profiles in an euthyroid population (2013) (0)
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- 17 beta-Hydroxysteroid dehydrogenase activity correlates with the type-2 17 beta-hydroxysteroid dehydrogenase mRNA abundance in human meningioma tumors. (1996) (0)
- LSC Abstract – Systemic and local metabolomics profiling reveals novel insights into the progression of emphysema (2016) (0)
- The plasma lipidomic signature of Abcb4–/– mice with secondary biliary fibrosis (2010) (0)
- Fgf9Y162C Mutation Alters Information Processing and Social Memory in Mice (2017) (0)
- Pilot study on the effects of cross-sex hormone treatment in transsexual persons on metabolism by means of metabolomics profiling (2015) (0)
- SrGAP3/MEGAP knockout mice express schizophrenia-related endophenotypes (2011) (0)
- Animal Cytogenetics and Comparative Mapping (2001) (0)
- Associations of endogenous androgens and sex hormone-binding globulin with kidney function and chronic kidney disease (2022) (0)
- SAT-740 Plasma Glucocorticoids and Mineralocorticoids Are Associated to Metabolic Syndrome Features in Women (2020) (0)
- Circulating glutamate concentration as a 3 biomarker of visceral obesity and associated 4 metabolic alterations 5 6 (2020) (0)
- Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives (2017) (0)
- Bezafibrate Reduces Elevated Hepatic Fumarate in Insulin-Deficient Mice (2022) (0)
- Induction of the nicotinamide riboside kinase NAD+ salvage pathway in skeletal muscle of H6PDH KO mice (2019) (0)
- Comprehensive metabolic characterization of serum osteocalcin action in a large non-diabetic sample (2017) (0)
- Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele (2013) (0)
- Lipid Dependence of D-3-yroxybutyrat Dehydrogenase (BDH) - Lipid Activation of 17β-Steroid Dehydrogenase-BDH Fusion Proteins (2007) (0)
- Adaptive mitochondrial regulation of the proteasome (2020) (0)
- The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes (2020) (0)
- Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles (2013) (0)
- Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington’s disease peripheral blood samples (2016) (0)
- Running title: Pfeiffer et al.; genome-wide DNA methylation and blood lipid levels (2015) (0)
- Mission to steroids (2009) (0)
- Correction to: A network-based conditional genetic association analysis of the human metabolome (2019) (0)
- Targeted metabolomics to predict the primary success of metformin monotherapy in type 2 diabetes (2016) (0)
- Functional characterization of two 20β-hydroxysteroid dehydrogenase type 2 homeologs from Xenopus laevis reveals multispecificity (2021) (0)
- Honoring a colleague and friend, Charles H. Blomquist (2010) (0)
- Identification of putative biomarkers for type 2 diabetes using metabolomics in the Korea Association REsource (KARE) cohort (2016) (0)
- Part B of the proposal Short web-based version Proposal full title : New technologies for targeted metabolomics (2008) (0)
- Preface (2010) (0)
- Distribution of phenotypes in hsd20b2 morphant zebrafish larvae. (2013) (0)
- Mitochondrial metabolism regulates cellular proteostasis (2020) (0)
- Characterization of human DHRS6, an orphan SDR enzyme: a novel, cytosolic type 2 R-β-hydroxybutyrate dehydrogenase (2005) (0)
- Y-Chromosome Genes Strongly Expressed in Acute Myeloid Leukaemia. (2007) (0)
- Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice (2018) (0)
- LysoPC-acyl C16:0 is associated with brown adipose tissue activity in men (2017) (0)
- Acylcarnitine profiles in serum and skeletal muscle and mRNA expression of the carnitine acyltransferases - CPT1B and CPT2 in muscle of dairy cows around parturition (2017) (0)
- Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies (2018) (0)
- STAT6 Expression Is Influenced By A Functional IgE-associated Polymorphism And Exposure To A Farming Environment (2010) (0)
- Endometrial cancer diagnostic and prognostic algorithms based on proteomics, metabolomics, and clinical data: a systematic review (2023) (0)
- Changes in metabolite profiles caused by genetically determined obesity in mice (2013) (0)
- Metabolic Signatures Elucidate the Effect of Body Mass Index on Type 2 Diabetes (2023) (0)
- Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms (2016) (0)
- University of Groningen Pre-Analytical Sample Quality (2015) (0)
- University of Dundee Processes Underlying Glycemic Deterioration in Type 2 Diabetes IMI DIRECT Consortium; Bizzotto, Roberto; Jennison, Christopher; Jones, Angus G.; Kurbasic, (2020) (0)
- Dynamic patterns of postprandial metabolic responses to three dietary challenges (2022) (0)
- Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study (2020) (0)
- Lessons from the Singapore cohorts showcase symposium-open call for collaborations. (2023) (0)
- DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function (2021) (0)
- Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes (2017) (0)
- Correction to: The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study (2020) (0)
- Endocrinology meets metabolomics : 1 achievements , pitfalls , and challenges 2 3 4 (2017) (0)
- FUNCTIONS OF 17BETA -HYDROXYSTEROID DEHYDROGENASE TYPE 4 (1998) (0)
- Physiology and Endocrinology 2 (2017) (0)
- Exposure to disinfection byproducts and risk of type 2 diabetes: a nested case–control study in the HUNT and Lifelines cohorts (2019) (0)
- H6PDH deficiency in muscle impacts amino acid metabolism (2014) (0)
- Gene Expression Pattern E expression of cholesterogenic genes is restricted to distinct domains and colocalizes with apoptotic regions in mice (2003) (0)
- Targeted metabolomics profiles are strongly correlated with nutritional patterns in women (2012) (0)
- Allele-Specific NF-ΚB-Binding Alters STAT6 Expression and Contributes to Genetic IgE Control. (2009) (0)
- EP555 Biomarkers for diagnosis and prognosis of endometrial carcinoma: BioEndoCar (2019) (0)
- Muscle and serum acylcarnitine profiles in dairy cows during the periparturient period [invited] (2016) (0)
- Abstract 464: BioEndoCar: in search of new Biomarkers for Diagnosis and Prognosis of Endometrial Carcinoma (2021) (0)
- Genome-wide association studies with metabolomics (2012) (0)
- Linkage of 17f-oestradiol dehydrogenase to actin by -( y-glutamyl)-lysine in porcine endometrial cells* (2005) (0)
- Introduction to metabolomics (2020) (0)
- Plasma metabolomics profile in patients with Cushing's syndrome (2016) (0)
- 10-28 Ali14, a Novel Gain-of-Function Mutation in Phospholipase C gamma 2, Causes Inflammatory Arthritis in the Mouse (2010) (0)
- Postprandial metabolite profiles associated with type 2 diabetes clearly stratify individuals with impaired fasting glucose (2017) (0)
- Differentiation between estradiol-17β dehydrogenase and estrone reductase by properties and assignments to cytoplasmic structures of porcine endometrium cells (1989) (0)
- PARATHYROID HORMONE TRANSLATIONAL AND CLINICAL ASPECTS Clinical and Biochemical Characterization of Risk Factors for Vertebral Fractures in Patients with Hypoparathyroidism (2020) (0)
- Genome-wide DNA methylation analysis reveals several loci important for blood lipid levels (2015) (0)
- Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics (2011) (0)
- Review Process File (2012) (0)
- Long term conservation of human metabolic phenotypes and link to heritability (2014) (0)
- Predicting and elucidating the etiology of fatty liver disease using a machine learning-based approach: an IMI DIRECT study (2020) (0)
- Short-Term Air Pollution Exposure Is Associated With Metabolite Levels In Two Cohorts From Augsburg, Germany (2015) (0)
- A metabolite ratio associates with measures of insulin secretion and altered risk of type 2 diabetes; a DIRECT study (2016) (0)
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What Schools Are Affiliated With Jerzy Adamski?
Jerzy Adamski is affiliated with the following schools:
