Jessica Kandel
#70,078
Most Influential Person Now
American physician
Jessica Kandel's AcademicInfluence.com Rankings
Jessica Kandelphilosophy Degrees
Philosophy
#12354
World Rank
#17152
Historical Rank
#2416
USA Rank
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#9196
World Rank
#11621
Historical Rank
#1599
USA Rank
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Philosophy
Jessica Kandel's Degrees
- Doctorate Medicine Harvard University
Why Is Jessica Kandel Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jessica Kandel is the Mary Campau Ryerson Professor of Surgery and the Vice-Chair for Academic Affairs in the Department of Surgery at the University of Chicago. Education Kandel graduated summa cum laude from Yale University in 1981, and completed her MD degree at Columbia University in 1985. She then went on to a General Surgery residency at the Massachusetts General Hospital in Boston . During her residency, Kandel completed a two-year surgical research fellowship with Dr. Judah Folkman at the Boston Children's Hospital, investigating mechanisms of tumor angiogenesis .
Jessica Kandel's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma (1991) (534)
- Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma (2002) (326)
- Regression of established tumors and metastases by potent vascular endothelial growth factor blockade (2003) (239)
- Phase I trial and pharmacokinetic study of bevacizumab in pediatric patients with refractory solid tumors: a Children's Oncology Group Study. (2008) (232)
- VEGF blocking therapy in the treatment of cancer (2003) (177)
- A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis. (2008) (161)
- Endothelial-Monocyte Activating Polypeptide Ii, a Novel Antitumor Cytokine That Suppresses Primary and Metastatic Tumor Growth and Induces Apoptosis in Growing Endothelial Cells (1999) (123)
- A Multi-Cancer Mesenchymal Transition Gene Expression Signature Is Associated with Prolonged Time to Recurrence in Glioblastoma (2012) (121)
- Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor. (2000) (112)
- Vascular remodeling marks tumors that recur during chronic suppression of angiogenesis. (2004) (107)
- Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo (2011) (107)
- Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors. (2012) (107)
- Ultrasonography/MRI Versus CT for Diagnosing Appendicitis (2014) (104)
- Vascular remodeling and clinical resistance to antiangiogenic cancer therapy. (2004) (89)
- Management of lymphatic malformations in children (2015) (84)
- Notch: a key regulator of tumor angiogenesis and metastasis. (2012) (80)
- Angiopoietin-1/Tie-2 activation contributes to vascular survival and tumor growth during VEGF blockade. (2009) (76)
- Genomic Profiling Maps Loss of Heterozygosity and Defines the Timing and Stage Dependence of Epigenetic and Genetic Events in Wilms' Tumors (2005) (71)
- Combination antiangiogenic therapy: increased efficacy in a murine model of Wilms tumor. (2001) (71)
- Association of plasma lipoproteins with postheparin lipase activities. (1986) (71)
- PDE-constrained multispectral imaging of tissue chromophores with the equation of radiative transfer (2010) (69)
- Sustained VEGF Blockade Results in Microenvironmental Sequestration of VEGF by Tumors and Persistent VEGF Receptor-2 Activation (2008) (67)
- Highly specific antiangiogenic therapy is effective in suppressing growth of experimental Wilms tumors. (2001) (64)
- Contrast ultrasound imaging for identification of early responder tumor models to anti-angiogenic therapy. (2012) (60)
- Pediatric lymphatic malformations: evolving understanding and therapeutic options (2016) (60)
- Effective therapy of a vascular tumor of infancy with vincristine. (2001) (59)
- Biomolecular markers and involution of hemangiomas. (2004) (57)
- Multiple Cutaneous Infantile Hemangiomas Associated With Hepatic Angiosarcoma: Case Report and Review of the Literature (2006) (56)
- Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature. (2004) (55)
- Primary nephrectomy and intraoperative tumor spill: report from the Children's Oncology Group (COG) renal tumors committee. (2013) (52)
- Suppression of primary tumor growth in a mouse model of human neuroblastoma. (2000) (45)
- Distinct response of experimental neuroblastoma to combination antiangiogenic strategies. (2002) (45)
- All angiogenesis is not the same: Distinct patterns of response to antiangiogenic therapy in experimental neuroblastoma and Wilms tumor. (2001) (41)
- Novel use of an established agent: Topotecan is anti-angiogenic in experimental Wilms tumor. (2001) (40)
- Inhibition of cyclooxygenase-2 disrupts tumor vascular mural cell recruitment and survival signaling. (2006) (37)
- Notch suppresses angiogenesis and progression of hepatic metastases. (2015) (37)
- Anti-VEGF antibody in experimental hepatoblastoma: suppression of tumor growth and altered angiogenesis. (2003) (35)
- Thalidomide is anti-angiogenic in a xenograft model of neuroblastoma. (2003) (35)
- Notch and VEGF pathways play distinct but complementary roles in tumor angiogenesis (2013) (32)
- Surgical protocol violations in children with renal tumors provides an opportunity to improve pediatric cancer care: a report from the Children's Oncology Group (2016) (31)
- Aberrant Lymphatic Endothelial Progenitors in Lymphatic Malformation Development (2015) (31)
- Metastasis correlates with production of vascular endothelial growth factor in a murine model of human Wilms' tumor. (1999) (30)
- Ovarian repositioning in pediatric cancer patients: Flexible techniques accommodate pelvic radiation fields (2007) (29)
- Reduced Toxicity Conditioning and Allogeneic Hematopoietic Progenitor Cell Transplantation for Recessive Dystrophic Epidermolysis Bullosa. (2015) (27)
- TNP-470 promotes initial vascular sprouting in xenograft tumors. (2004) (27)
- Congenital Cutaneous Hemangioma Causing Cardiac Failure: A Case Report and Review of the Literature (2013) (25)
- p53 accumulation in favorable-histology Wilms tumor is associated with angiogenesis and clinically aggressive disease. (2002) (25)
- Human epidermal growth factor receptor signaling contributes to tumor growth via angiogenesis in her2/neu-expressing experimental Wilms' tumor. (2003) (24)
- Monitoring early tumor response to drug therapy with diffuse optical tomography. (2012) (24)
- Topotecan is anti-angiogenic in experimental hepatoblastoma. (2002) (24)
- Pediatric Modification of the Medically Necessary, Time-Sensitive Scoring System for Operating Room Procedure Prioritization During the COVID-19 Pandemic (2020) (23)
- Vascular endothelial growth factor blockade rapidly elicits alternative proangiogenic pathways in neuroblastoma. (2009) (23)
- Clinical Spectrum of Capillary Malformation–Arteriovenous Malformation Syndrome Presenting to a Pediatric Dermatology Practice: A Retrospective Study (2015) (22)
- Preoperative angiography with embolization and radiofrequency ablation as novel adjuncts to safe surgical resection of a large, vascular sacrococcygeal teratoma (2006) (22)
- Staphylococcus aureus alpha toxin activates Notch in vascular cells (2018) (21)
- Vascular characterization of clear cell sarcoma of the kidney in a child: a case report and review. (2009) (19)
- Initial Experience With Propranolol Treatment of Lymphatic Anomalies: A Case Series (2016) (19)
- Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma (2018) (19)
- Lack of evidence for tissue hypoxia as a contributing factor in anastomotic leak following colon anastomosis and segmental devascularization in rats (2017) (17)
- Severe Mycoplasma pneumoniae infection requiring extracorporeal membrane oxygenation with concomitant ischemic stroke in a child (2013) (17)
- A metastasizing model of anaplastic human Wilms tumor in the nude mouse. (1998) (16)
- Correlation of tumor-associated macrophages and clinicopathological factors in Wilms tumor (2013) (16)
- Pathological angiogenesis in a murine model of human Wilms' tumor. (1999) (16)
- Inhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor (2011) (14)
- Blockade of her2/neu decreases VEGF expression but does not alter HIF-1 distribution in experimental Wilms tumor. (2003) (13)
- Antiangiogenic therapy for the treatment of pediatric solid malignancies. (2004) (12)
- Contrast-enhanced sonography as a novel tool for assessment of vascular malformations (2010) (12)
- Quality and Extent of Locum Tenens Coverage in Pediatric Surgical Practices (2015) (11)
- Neonatal hepatic mesenchymal hamartoma causing cardiac failure and disseminated intravascular coagulopathy. (2009) (11)
- Perfusion-guided sonopermeation of neuroblastoma: a novel strategy for monitoring and predicting liposomal doxorubicin uptake in vivo (2020) (11)
- Evaluation of a water-soluble contrast protocol for nonoperative management of pediatric adhesive small bowel obstruction. (2019) (10)
- CM-AVM syndrome in a neonate: case report and treatment with a novel flow reduction strategy (2012) (10)
- How the microbiome is shaping our understanding of cancer biology and its treatment (2017) (8)
- Combined optical tomographic and magnetic resonance imaging of tumor bearing mice (2005) (7)
- Monitoring tumor growth and treatment in small animals with magnetic resonance and optical tomographic imaging (2006) (7)
- Inter-rater reliability of surgical reviews for AREN03B2: a COG renal tumor committee study. (2014) (7)
- Polyplex-microbubbles for improved ultrasound-mediated gene therapy (2013) (6)
- Resistance of a VEGF-producing tumor to anti-VEGF antibody: unimpeded growth of human rhabdoid tumor xenografts. (2002) (6)
- Real-time central review: A report of the first 3,000 patients enrolled on the Children’s Oncology Group Renal Tumor Biology and Risk Stratification protocol AREN03B2. (2014) (5)
- Optics InfoBase Conference Papers (2006) (4)
- Slug-based epithelial-mesenchymal transition gene signature is associated with prolonged time to recurrence in glioblastoma (2011) (4)
- Dynamic Fluorescence Imaging For The Detection of Vascular Changes in Anti-Angiogenic Drug Therapy (2010) (4)
- Bowel obstruction from intramural hematoma in two children treated with low molecular weight heparin: Case report and review of the literature (2014) (4)
- A phase I study of bevacizumab in children with refractory solid tumors: A Children's Oncology Group study. (2006) (4)
- Notch: Cell fate determination from vascular development to human vasculopathy (2004) (3)
- Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging (2010) (3)
- Polyplex-microbubbles for ultrasound-mediated gene therapy (2013) (3)
- Optical Tomographic and Magnetic Resonance Imaging of Tumor Growth and Regression in Mice treated with VEGF Blockade (2005) (3)
- Value-based surgery physician compensation model - review of the literature. (2022) (3)
- Image-guided esophageal anastomosis in esophageal atresia. (2012) (2)
- Serendipity: translational research, high quality care, and the children's hospital. Jay and Margie Grosfeld Lecture. (2014) (2)
- Cancer invasion associated gene expression signature is present in differentially expressed genes in the reprogramming of fibroblasts into stem cells (2011) (2)
- Evaluating tumor angiogenesis. (2013) (2)
- Early Detection of Tumor Vascular Response to Anti-Angiogenic Drugs with Optical Tomography (2010) (2)
- Fighting the Moral Distress of Idleness (2020) (2)
- Transport-theory based multispectral imaging with PDE-constrained optimization (2011) (2)
- Angiogenesis in Tumour Development and Metastasis (2010) (1)
- Pediatric Medically Necessary, Time-Sensitive Scoring Tool Facilitates Dynamic and Flexible Decision-Making and Triage for Procedures: In Reply to González Villarreal and Colleagues. (2020) (1)
- Human Cancer Cells Express Slug-based Epithelial-Mesenchymal Transition Gene Signature Obtained in Vivo (2011) (1)
- Comparing tumor response to VEGF blockade therapy using high frequency ultrasound imaging with size-selected microbubble contrast agents (2010) (1)
- Pediatric surgical transitional care. Preface. (2015) (1)
- Optical tomographic imaging of tumor response to anti-angiogenic drugs in small animals (2010) (0)
- Optical tomographic imaging of tumor hemodynamics during anti-VEGF treatment in mice (2006) (0)
- Optical tomographic monitoring of vascular responses to anti-angiogenic drugs in preclinical tumor models (2011) (0)
- Metronomic rapamycin is anti-angiogenic in Ewing's sarcoma (2008) (0)
- Abstract 1729: Novel liposomal topotecan formulation has a lower IC50 than the free form on neuroblastoma cells (2020) (0)
- Editorial (2019) (0)
- Methode de regression tumorale avec des inhibiteurs vegf (2004) (0)
- AML-1/Angiopoietin signaling contributes to hepatoblastoma recurrence during VEGF blockade (2006) (0)
- Changing paradigms in pediatric surgery. (2019) (0)
- Abstract 2325: Increase in neuroblastoma metastasis after dual inhibition of VEGF and Notch (2012) (0)
- Propranolol: A Potential Therapy for Lymphatic Malformations (2014) (0)
- Inhibition of host Notch function disrupts hepatic vasculature, and promotes tumor growth (2012) (0)
- Abstract 1282: Notch and VEGF regulate tumor endothelial cell survival (2010) (0)
- R. Peter Altman, MD, 1934 to 2011 (2011) (0)
- A Novel Anti-Angiogenic Factor Suppresses Hemangioma Growth • 353 (1996) (0)
- Abstract 376: Sonoporated size selected microbubblesand liposomal doxorubicinadditively induce apoptosis in neuroblastoma xenografts (2022) (0)
- Abstract 1132: Identification of synthetic lethal genes to MYCN-amplified neuroblastoma. (2013) (0)
- Perfusion-Guided Monitoring of Tumor Response to Sonoporation and Prediction of Liposomal Doxorubicin Uptake Using Microbubble Contrast Agents (2019) (0)
- Editorial: Changing paradigms in pediatric surgery. (2019) (0)
- Abstract 2809: Deficiency of Notch-1 signaling in liver increases neuroblastoma hepatic metastases. (2013) (0)
- Staphylococcus aureus alpha toxin activates Notch in vascular cells (2018) (0)
- Vascular Endothelial Growth Factor Expression and Pulmonary Development in Murine Fetal Heart-Lung Culture (1999) (0)
- Abstract 2055:Staphylococcus aureusalpha toxin activates Notch in endothelial cells (2018) (0)
- Availability of Resources for After-Hours Surgical Management of Eye Injuries (2018) (0)
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Jessica Kandel is affiliated with the following schools:
