Jesús Avila

Jesús Avila's AcademicInfluence.com Rankings

Jesús Avila

Biology

#5496

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#7989

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Neuroscience

#619

World Rank

#646

Historical Rank

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Biology

Jesús Avila's Degrees

Masters Biology Stanford University

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Jesús Avila's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease (2019) (879)
Functional Recovery of Paraplegic Rats and Motor Axon Regeneration in Their Spinal Cords by Olfactory Ensheathing Glia (2000) (816)
Decreased nuclear β‐catenin, tau hyperphosphorylation and neurodegeneration in GSK‐3β conditional transgenic mice (2001) (798)
Role of tau protein in both physiological and pathological conditions. (2004) (788)
Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function (2000) (482)
Structural Insights and Biological Effects of Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418* (2003) (472)
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. (2001) (419)
Glycogen synthase kinase 3: a drug target for CNS therapies (2004) (418)
Olfactory ensheathing glia: properties and function (1998) (369)
GSK-3β, a pivotal kinase in Alzheimer disease (2014) (350)
Spatial learning deficit in transgenic mice that conditionally over‐express GSK‐3β in the brain but do not form tau filaments (2002) (333)
Glycogen synthase kinase‐3 inhibition is integral to long‐term potentiation (2007) (332)
Analysis of microtubule-associated protein tau glycation in paired helical filaments. (1994) (331)
Lithium inhibits Alzheimer's disease‐like tau protein phosphorylation in neurons (1997) (328)
Polymerization of τ into Filaments in the Presence of Heparin: The Minimal Sequence Required for τ ‐ τ Interaction (1996) (322)
A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo (2009) (321)
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? (2002) (302)
Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies. (2005) (295)
Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. (2003) (290)
GSK3: A possible link between beta amyloid peptide and tau protein (2010) (274)
Neuronal Induction of the Immunoproteasome in Huntington's Disease (2003) (263)
Tau phosphorylation and aggregation in Alzheimer's disease pathology (2006) (255)
Lithium protects cultured neurons against β‐amyloid‐induced neurodegeneration (1999) (250)
Full Reversal of Alzheimer's Disease-Like Phenotype in a Mouse Model with Conditional Overexpression of Glycogen Synthase Kinase-3 (2006) (244)
GSK3 and tau: two convergence points in Alzheimer's disease. (2012) (243)
Role of the Pi3k Regulatory Subunit in the Control of Actin Organization and Cell Migration (2000) (237)
Extracellular tau is toxic to neuronal cells (2006) (236)
Controlled proteolysis of tubulin by subtilisin: localization of the site for MAP2 interaction. (1984) (236)
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells (2008) (215)
Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly. (1984) (212)
Chronic lithium administration to FTDP‐17 tau and GSK‐3β overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre‐formed neurofibrillary tangles do not revert (2006) (210)
Revisiting the Role of Acetylcholinesterase in Alzheimer’s Disease: Cross-Talk with P-tau and β-Amyloid (2011) (205)
FTDP-17 Mutations in tau Transgenic Mice Provoke Lysosomal Abnormalities and Tau Filaments in Forebrain (2001) (204)
In Alzheimer's Disease, Heme Oxygenase Is Coincident with Alz50, an Epitope of τ Induced by 4‐Hydroxy‐2‐Nonenal Modification (2000) (200)
Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus (2004) (191)
Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease (1992) (190)
Tau – an inhibitor of deacetylase HDAC6 function (2009) (179)
Huntington's disease is a four-repeat tauopathy with tau nuclear rods (2014) (178)
Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model. (2003) (178)
A walk through tau therapeutic strategies (2019) (172)
Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells. (1993) (170)
Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice (2005) (166)
Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction. (1996) (164)
Regulation of microtubule dynamics by microtubule-associated protein expression and phosphorylation during neuronal development. (1994) (163)
Microtubule-associated protein tau is phosphorylated by protein kinase C on its tubulin binding domain. (1992) (162)
Alzheimer’s disease as an inflammatory disease (2017) (161)
A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease (2020) (153)
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models (2005) (149)
Tissue-nonspecific Alkaline Phosphatase Promotes the Neurotoxicity Effect of Extracellular Tau* (2010) (145)
A casein kinase II-related activity is involved in phosphorylation of microtubule-associated protein MAP-1B during neuroblastoma cell differentiation (1988) (145)
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles (2012) (144)
Evidence for the role of MAP1B in axon formation. (2001) (144)
Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo. (2015) (141)
Oxidative imbalance in alzheimer’s disease (2007) (140)
Review: postchaperonin tubulin folding cofactors and their role in microtubule dynamics. (2001) (138)
Atypical, non-standard functions of the microtubule associated Tau protein (2017) (138)
Role of Neuroinflammation in Adult Neurogenesis and Alzheimer Disease: Therapeutic Approaches (2013) (134)
The role of extracellular Tau in the spreading of neurofibrillary pathology (2014) (133)
Analysis of the expression, distribution and function of cyclin dependent kinase 5 (cdk5) in developing cerebellar macroneurons. (1997) (132)
Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells (2003) (131)
MAP1B Is Required for Netrin 1 Signaling in Neuronal Migration and Axonal Guidance (2004) (130)
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer’s disease (2008) (130)
DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease (2013) (130)
N-terminal Cleavage of GSK-3 by Calpain (2007) (128)
High Molecular Weight Neurofilament Proteins Are Physiological Substrates of Adduction by the Lipid Peroxidation Product Hydroxynonenal* (2002) (127)
Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration. (1999) (126)
Glycosaminoglycans and β-amyloid, prion and tau peptides in neurodegenerative diseases (2002) (125)
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. (2005) (124)
New perspectives on the role of tau in Alzheimer's disease. Implications for therapy. (2014) (123)
Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns (2016) (122)
Absence of CX3CR1 impairs the internalization of Tau by microglia (2017) (121)
Cooexpression of FTDP-17 tau and GSK-3β in transgenic mice induce tau polymerization and neurodegeneration (2006) (120)
Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. (2002) (120)
Localization of the tubulin binding site for tau protein. (1985) (117)
Estradiol Prevents Neural Tau Hyperphosphorylation Characteristic of Alzheimer's Disease (2005) (116)
Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4‐hydroxy‐2‐nonenal (2000) (114)
Deconstructing Mitochondrial Dysfunction in Alzheimer Disease (2013) (113)
The marine compound spisulosine, an inhibitor of cell proliferation, promotes the disassembly of actin stress fibers. (2000) (112)
Polymerization of tau peptides into fibrillar structures. The effect of FTDP‐17 mutations (1999) (112)
Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3. (2003) (111)
PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. (2016) (109)
Alpha-helix structure in Alzheimer's disease aggregates of tau-protein. (2002) (109)
Microtubule-associated protein 1B function during normal development, regeneration, and pathological conditions in the nervous system. (2004) (109)
The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer’s disease (2013) (108)
Role of glycogen synthase kinase-3 in Alzheimer’s disease pathogenesis and glycogen synthase kinase-3 inhibitors (2010) (108)
A role of MAP1B in Reelin-dependent neuronal migration. (2005) (108)
GSK-3β overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo (2013) (107)
Formation of aberrant phosphotau fibrillar polymers in neural cultured cells. (2002) (105)
Tau Dephosphorylation at Tau-1 Site Correlates with its Association to Cell Membrane (2004) (105)
Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease. (2009) (105)
Tubulin phosphorylation by casein kinase II is similar to that found in vivo (1987) (103)
Inhibition of Glycogen Synthase Kinase 3&bgr; During Heart Failure Is Protective (2007) (102)
Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits (2010) (98)
Tau Overexpression Results in Its Secretion via Membrane Vesicles (2012) (98)
GSK3beta-mediated phosphorylation of the microtubule-associated protein 2C (MAP2C) prevents microtubule bundling. (2000) (97)
Characteristics and consequences of muscarinic receptor activation by tau protein (2009) (96)
Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease. (1986) (95)
A cell division mutant of drosophila with a functionally abnormal spindle (1985) (94)
Glycogen Synthase Kinase-3 Plays a Crucial Role in Tau Exon 10 Splicing and Intranuclear Distribution of SC35 (2004) (93)
Regulation of GSK3 isoforms by phosphatases PP1 and PP2A (2010) (93)
Expression of the ghrelin and neurotensin systems is altered in the temporal lobe of Alzheimer's disease patients. (2010) (92)
The antitumoral compound Kahalalide F acts on cell lysosomes. (1996) (92)
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. (2006) (91)
Phosphorylation of alpha-tubulin carboxyl-terminal tyrosine prevents its incorporation into microtubules. (1987) (90)
Phosphorylation of tubulin by a calmodulin-dependent protein kinase. (1986) (89)
Tau Phosphorylation by GSK3 in Different Conditions (2012) (88)
Characterization of a double (amyloid precursor protein-tau) transgenic: Tau phosphorylation and aggregation (2005) (87)
Localization of the high affinity calcium-binding site on tubulin molecule. (1986) (85)
Phosphorylation of a neuronal-specific beta-tubulin isotype. (1990) (84)
Physicochemical characterization of the heat-stable microtubule-associated protein MAP2. (1986) (84)
Expression of unphosphorylated class III β‐tubulin isotype in neuroepithelial cells demonstrates neuroblast commitment and differentiation (1999) (83)
Selective alterations of neurons and circuits related to early memory loss in Alzheimer’s disease (2014) (83)
The role of glycogen synthase kinase 3 in the early stages of Alzheimers’ disease (2008) (82)
Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau (2007) (81)
Participation of structural microtubule‐associated proteins (MAPs) in the development of neuronal polarity (2002) (81)
Glycogen synthase kinase-3 (GSK-3) inhibitors for the treatment of Alzheimer's disease. (2010) (81)
Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease (2017) (80)
Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain (2000) (80)
Regulation of neuronal cytoskeleton by lysophosphatidic acid: role of GSK-3. (2002) (80)
The distribution and phosphorylation of the microtubule-associated protein MAP 1B in growth cones (1991) (77)
The role of GSK3 in Alzheimer disease (2009) (77)
The inhibition of phosphatidylinositol‐3‐kinase induces neurite retraction and activates GSK3 (2001) (77)
GSK3β overexpression induces neuronal death and a depletion of the neurogenic niches in the dentate gyrus (2010) (75)
MAP1B regulates microtubule dynamics by sequestering EB1/3 in the cytosol of developing neuronal cells (2013) (75)
Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer’s Disease-Associated Presenilin 1 Mutation (2017) (74)
Small heat shock proteins Hsp27 or αB‐crystallin and the protein components of neurofibrillary tangles: Tau and neurofilaments (2008) (74)
A New Mutation of the τ Gene, G303V, in Early-Onset Familial Progressive Supranuclear Palsy (2005) (74)
Role of glycosaminoglycans in determining the helicity of paired helical filaments. (1997) (73)
GSK-3 inhibitors for Alzheimer’s disease (2007) (72)
Characterization and structural aspects of the enhanced assembly of tubulin after removal of its carboxyl-terminal domain. (1986) (72)
Hyperexcitability and epileptic seizures in a model of frontotemporal dementia (2013) (72)
Absence of microglial CX3CR1 impairs the synaptic integration of adult-born hippocampal granule neurons (2018) (71)
In vitro assembly of tau protein: mapping the regions involved in filament formation. (2001) (71)
New Features about Tau Function and Dysfunction (2016) (71)
Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response. (2002) (71)
GSK-3 Mouse Models to Study Neuronal Apoptosis and Neurodegeneration (2011) (69)
Role of MAP1B in axonal retrograde transport of mitochondria. (2006) (68)
A discrete repeated sequence defines a tubulin binding domain on microtubule-associated protein tau. (1989) (68)
M1 muscarinic receptor activation protects neurons from β-amyloid toxicity. A role for Wnt signaling pathway (2004) (67)
Tau Protein and Adult Hippocampal Neurogenesis (2012) (67)
Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis (2016) (67)
Microtubule-associated protein MAP1B showing a fetal phosphorylation pattern is present in sites of neurofibrillary degeneration in brains of Alzheimer's disease patients. (1994) (66)
Association of casein kinase II with microtubules. (1989) (66)
Neuronal apoptosis and reversible motor deficit in dominant‐negative GSK‐3 conditional transgenic mice (2007) (66)
The FTDP‐17‐Linked Mutation R406W Abolishes the Interaction of Phosphorylated Tau with Microtubules (2000) (66)
MAP-1 and MAP-2 binding sites at the C-terminus of beta-tubulin. Studies with synthetic tubulin peptides. (1991) (66)
Tau Structures (2016) (65)
Expression of Somatostatin, cortistatin, and their receptors, as well as dopamine receptors, but not of neprilysin, are reduced in the temporal lobe of Alzheimer's disease patients. (2010) (65)
The Role of Microglia in the Spread of Tau: Relevance for Tauopathies (2018) (64)
BDNF production by olfactory ensheathing cells contributes to axonal regeneration of cultured adult CNS neurons (2007) (64)
Binding of Hsp90 to tau promotes a conformational change and aggregation of tau protein. (2009) (63)
Glycogen Synthase Kinase-3 Is Activated in Neuronal Cells by Gα12 and Gα13 by Rho-Independent and Rho-Dependent Mechanisms (2002) (63)
Extracellular Monomeric Tau Is Internalized by Astrocytes (2019) (63)
Zeta 14-3-3 protein favours the formation of human tau fibrillar polymers (2004) (63)
Role of cofactors B (TBCB) and E (TBCE) in tubulin heterodimer dissociation. (2007) (62)
Sulphated glycosaminoglycans prevent the neurotoxicity of a human prion protein fragment. (1998) (62)
A new mutation of the tau gene, G303V, in early-onset familial progressive supranuclear palsy. (2005) (62)
Biochemical, Ultrastructural, and Reversibility Studies on Huntingtin Filaments Isolated from Mouse and Human Brain (2004) (61)
Binding of heat-shock protein 70 (hsp70) to tubulin. (1994) (61)
Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy (2018) (61)
Localization of differentially phosphorylated isoforms of microtubule-associated protein 1B in cultured rat hippocampal neurons (1994) (61)
Tau regulates the localization and function of End‐binding proteins 1 and 3 in developing neuronal cells (2015) (60)
Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons (2002) (60)
Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons (2017) (58)
Characterisation of antimitotic products from marine organisms that disorganise the microtubule network: ecteinascidin 743, isohomohalichondrin-B and LL-15. (1996) (57)
Taurine, an inducer for tau polymerization and a weak inhibitor for amyloid-β-peptide aggregation (2007) (57)
The marine sphingolipid-derived compound ES 285 triggers an atypical cell death pathway (2007) (57)
Glycogen Synthase Kinase-3 Modulates Neurite Outgrowth in Cultured Neurons: Possible Implications for Neurite Pathology in Alzheimer's Disease. (1999) (56)
Immunotherapy for neurological diseases. (2008) (55)
Tau Phosphorylation, Aggregation, and Cell Toxicity (2006) (54)
Post-translational modifications of tau protein. (2006) (53)
Phosphorylation and dephosphorylation in the proline-rich C-terminal domain of microtubule-associated protein 2. (1996) (53)
Unraveling human adult hippocampal neurogenesis (2020) (53)
Phosphorylation of tubulin enhances its interaction with membranes (1986) (53)
Novel connection between newborn granule neurons and the hippocampal CA2 field (2015) (53)
Propagation of Tau via Extracellular Vesicles (2019) (53)
The tau gene A0 allele and progressive supranuclear palsy (1999) (53)
Effects of DNA on microtubule assembly. (1980) (52)
Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation. (2011) (51)
Tau factor polymers are similar to paired helical filaments of Alzheimer's disease (1988) (51)
Dual effects of increased glycogen synthase kinase-3β activity on adult neurogenesis. (2013) (51)
Glial fibrillary acidic protein is a major target of glycoxidative and lipoxidative damage in Pick's disease (2006) (51)
Tau pathology-mediated presynaptic dysfunction (2016) (50)
Function of tau protein in adult newborn neurons (2009) (50)
“Tau Oligomers,” What We Know and What We Don’t Know (2014) (49)
Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer’s disease (2019) (49)
Aluminum induces the in vitro aggregation of bovine brain cytoskeletal proteins (1990) (49)
Microtubule‐associated protein MAP2 preferentially binds to a dA/dT sequence present in mouse satellite DNA. (1983) (48)
Suppression of Parkin enhances nigrostriatal and motor neuron lesion in mice over-expressing human-mutated tau protein. (2006) (48)
Immortalized olfactory ensheathing glia promote axonal regeneration of rat retinal ganglion neurons (2003) (48)
New insights into the role of glycogen synthase kinase-3 in Alzheimer's disease (2014) (48)
Peripherally triggered and GSK-3β-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen (2014) (48)
GSK3 inhibitors and disease. (2009) (48)
Tissue-nonspecific Alkaline Phosphatase Regulates Purinergic Transmission in the Central Nervous System During Development and Disease (2014) (47)
Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers. (2004) (47)
N-methyl-d-aspartate stimulates the dephosphorylation of the microtubule-associated protein 2 and potentiates excitatory synaptic pathways in the rat hippocampus (1993) (47)
GSK-3 and Tau: A Key Duet in Alzheimer’s Disease (2021) (46)
Tau antagonizes end-binding protein tracking at microtubule ends through a phosphorylation-dependent mechanism (2016) (46)
Tau aggregates and tau pathology. (2008) (46)
GSK3β Is Involved in the Relief of Mitochondria Pausing in a Tau-Dependent Manner (2011) (46)
Microtubule functions. (1992) (45)
GSK-3 dependent phosphoepitopes recognized by PHF-1 and AT-8 antibodies are present in different tau isoforms (2003) (45)
Preferential binding of hog brain microtubule-associated proteins to mouse satellite versus bulk DNA preparations (1978) (44)
Regulation of a site-specific phosphorylation of the microtubule-associated protein 2 during the development of cultured neurons (1998) (44)
The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau (2002) (44)
Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease. (2005) (44)
Characteristics of the binding of thioflavin S to tau paired helical filaments. (2006) (43)
Role for the α-helix in aberrant protein aggregation (2005) (42)
Glycogen synthase kinase 3 phosphorylates recombinant human tau protein at serine‐262 in the presence of heparin (or tubulin) (1995) (42)
Binding of microtubule proteins to DNA: specificity of the interaction. (1978) (42)
Semaphorin 3C preserves survival and induces neuritogenesis of cerebellar granule neurons in culture (2003) (42)
Abnormal tau phosphorylation in the thorny excrescences of CA3 hippocampal neurons in patients with Alzheimer's disease. (2011) (41)
Testing the ubiquitin–proteasome hypothesis of neurodegeneration in vivo (2004) (41)
Characterization of microtubule-associated protein MAP1B: phosphorylation state, light chains, and binding to microtubules. (1996) (41)
The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas (2020) (41)
Lithium, a Potential Protective Drug in Alzheimer’s Disease (2008) (41)
In vitro conditions for the self-polymerization of the microtubule-associated protein, tau factor. (1987) (40)
The role of the Maillard reaction in other pathologies: Alzheimer's disease. (1996) (40)
Tau isoform with three microtubule binding domains is a marker of new axons generated from the subgranular zone in the hippocampal dentate gyrus: implications for Alzheimer's disease. (2012) (40)
Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1. (2005) (40)
Enhaced induction of the immunoproteasome by interferon gamma in neurons expressing mutant huntingtin (2009) (40)
Heme catabolism and heme oxygenase in neurodegenerative disease. (2004) (39)
Reactive oxygen: its sources and significance in Alzheimer disease. (2002) (38)
MAP1B‐dependent Rac activation is required for AMPA receptor endocytosis during long‐term depression (2013) (38)
Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease (2019) (38)
Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective. (2019) (38)
Calmodulin binds to a tubulin binding site of the microtubule-associated protein tau (1990) (38)
Different Susceptibility to Neurodegeneration of Dorsal and Ventral Hippocampal Dentate Gyrus: A Study with Transgenic Mice Overexpressing GSK3β (2011) (38)
Tau kinases and phosphatases (2007) (37)
Microtubule-Associated Protein 1B Interaction with Tubulin Tyrosine Ligase Contributes to the Control of Microtubule Tyrosination (2007) (37)
The Ever-Changing Morphology of Hippocampal Granule Neurons in Physiology and Pathology (2016) (37)
Quantitation and characterization of the microtubule associated MAP2 in porcine tissues and its isolation from porcine (PK15) and human (HeLa) cell lines. (1982) (37)
Incorporation of tubulin subunits into dimers requires GTP hydrolysis. (1993) (37)
Microglia in Alzheimer’s Disease in the Context of Tau Pathology (2020) (37)
Thermodynamics of the Interaction between Alzheimer's Disease Related Tau Protein and DNA (2014) (37)
Limited proteolysis of tubulin and the localization of the binding site for colchicine. (1984) (37)
Phosphorylation of microtubule-associated proteins by protein kinase CK2 in neuritogenesis. (1994) (36)
A modified form of microtubule-associated tau protein is the main component of paired helical filaments. (1988) (36)
Tau in neurodegenerative diseases: Tau phosphorylation and assembly (2009) (36)
Beta-Amyloid Impairs Reelin Signaling (2013) (36)
Tau function and dysfunction in neurons: its role in neurodegenerative disorders. (2002) (36)
Decreased CX3CL1 Levels in the Cerebrospinal Fluid of Patients With Alzheimer’s Disease (2018) (35)
Soluble Tau has devastating effects on the structural plasticity of hippocampal granule neurons (2017) (35)
The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from β-amyloid neurotoxicity by acting on Wnt signaling components (2005) (35)
Blocking Effects of Human Tau on Squid Giant Synapse Transmission and Its Prevention by T-817 MA (2011) (35)
A Multilevel View of the Development of Alzheimer’s Disease (2020) (35)
Further understanding of tau phosphorylation: implications for therapy (2015) (35)
Somatic signature of brain-specific single nucleotide variations in sporadic Alzheimer's disease. (2014) (35)
Characterization of proteins immunologically related to brain microtubule-associated protein MAP-1B in non-neural cells. (1989) (34)
Glycogen synthase kinase-3 is activated in neuronal cells by Galpha12 and Galpha13 by Rho-independent and Rho-dependent mechanisms. (2002) (34)
Tau protein role in sleep-wake cycle. (2010) (34)
Localization of the Phosphorylation Sites for Different Kinases in the Microtubule‐Associated Protein MAP2 (1987) (34)
End binding protein‐1 (EB1) complements microtubule‐associated protein‐1B during axonogenesis (2005) (34)
Tau Spreading Mechanisms; Implications for Dysfunctional Tauopathies (2018) (34)
Binding of microtubule protein to DNA and chromatin: possibility of simultaneous linkage of microtubule to nucleic and assembly of the microtubule structure. (1981) (34)
Progressive supranuclear palsy and tau hyperphosphorylation in a patient with a C212Y parkin mutation. (2002) (34)
Alzheimer disease: Caspases first (2010) (34)
Cognitive Decline in Neuronal Aging and Alzheimer's Disease: Role of NMDA Receptors and Associated Proteins (2017) (34)
P24, a glycogen synthase kinase 3 (GSK 3) inhibitor. (2002) (33)
In Vivo Reprogramming Ameliorates Aging Features in Dentate Gyrus Cells and Improves Memory in Mice (2020) (33)
Abnormal meiotic spindles cause a cascade of defects during spermatogenesis in asp males of Drosophila. (1990) (33)
Adeno-associated viral vector serotype 9–based gene therapy for Niemann-Pick disease type A (2019) (32)
Dephosphorylated rather than hyperphosphorylated Tau triggers a pro-inflammatory profile in microglia through the p38 MAPK pathway (2018) (32)
Tau phosphorylation and assembly. (2004) (31)
Inhibition of PMCA activity by tau as a function of aging and Alzheimer's neuropathology. (2015) (31)
Understanding the relationship between GSK-3 and Alzheimer’s disease: a focus on how GSK-3 can modulate synaptic plasticity processes (2013) (31)
Location of the regions recognized by five commercial antibodies on the tubulin molecule. (1986) (31)
Forced swimming sabotages the morphological and synaptic maturation of newborn granule neurons and triggers a unique pro-inflammatory milieu in the hippocampus (2016) (31)
Acetylcholine receptors and tau phosphorylation. (2006) (30)
Tau protein provides DNA with thermodynamic and structural features which are similar to those found in histone-DNA complex. (2014) (30)
The zeta isozyme of protein kinase C binds to tubulin through the pseudosubstrate domain. (1997) (30)
Differential effects of tumor necrosis factor on the growth and differentiation of neuroblastoma and glioma cells. (1991) (30)
Tau deficiency leads to the upregulation of BAF‐57, a protein involved in neuron‐specific gene repression (2010) (29)
Tissue-type plasminogen activator (tPA) is the main plasminogen activator associated with isolated rat nerve growth cones (1994) (29)
Kidins220 accumulates with tau in human Alzheimer's disease and related models: modulation of its calpain-processing by GSK3β/PP1 imbalance. (2013) (29)
Sources of extracellular tau and its signaling. (2014) (29)
Nuclear localization of N‐terminal mutant huntingtin is cell cycle dependent (2002) (29)
The interaction between subunits in the tubulin dimer. (1985) (29)
Phosphorylation modulates the alpha-helical structure and polymerization of a peptide from the third tau microtubule-binding repeat. (2005) (28)
Role of the PI 3 K Regulatory Subunit in the Control of Actin Organization and Cell Migration (2000) (28)
Tangling with hypothermia (2004) (28)
Effect of specific proteolytic cleavages on tubulin polymer formation. (1988) (28)
NMDA-glutamate receptors regulate phosphorylation of dendritic cytoskeletal proteins in the hippocampus (1997) (28)
The in vitro formation of recombinant tau polymers: effect of phosphorylation and glycation. (1996) (28)
Phosphorylation of stathmin modulates its function as a microtubule depolymerizing factor (1998) (28)
Phosphorylation of Tau Protein Associated as a Protective Mechanism in the Presence of Toxic, C-Terminally Truncated Tau in Alzheimer's Disease (2013) (28)
Distribution of CK2, its substrate MAP1B and phosphatases in neuronal cells (2004) (27)
A protein related to brain microtubule-associated protein MAP1B is a component of the mammalian centrosome. (1994) (27)
Additional mechanisms conferring genetic susceptibility to Alzheimer’s disease (2015) (27)
PARK 2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer ’ s disease (2016) (27)
Tau is required for the function of extrasynaptic NMDA receptors (2019) (27)
Variations in in vivo phosphorylation at the proline-rich domain of the microtubule-associated protein 2 (MAP2) during rat brain development. (1995) (27)
Microtubule protein phosphorylation in neuroblastoma cells and neurite growth (1991) (27)
Inhibition of GSK3 dependent tau phosphorylation by metals. (2006) (27)
Assembly in vitro of tau protein and its implications in Alzheimer's disease. (2004) (27)
Identification of zinc-binding sites of proteins: zinc binds to the amino-terminal region of tubulin. (1988) (27)
Tau-related protein present in paired helical filaments has a decreased tubulin binding capacity as compared with microtubule-associated protein tau. (1991) (27)
Toward common mechanisms for risk factors in Alzheimer's syndrome (2017) (26)
Tau function and dysfunction in neurons (2002) (26)
Isolation of a phosphorylated soluble Tau fraction from Alzheimer's disease brain (1995) (26)
Role of tau N-terminal motif in the secretion of human tau by End Binding proteins (2019) (26)
Characterization of microtubule-associated protein phosphoisoforms present in isolated growth cones. (1995) (26)
Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies (2016) (26)
Tau aggregation followed by atomic force microscopy and surface plasmon resonance, and single molecule tau-tau interaction probed by atomic force spectroscopy. (2009) (26)
A Simple Model to Study Tau Pathology (2016) (26)
The mixture of "ecstasy" and its metabolites impairs mitochondrial fusion/fission equilibrium and trafficking in hippocampal neurons, at in vivo relevant concentrations. (2014) (26)
Role of tau protein on neocortical and hippocampal oscillatory patterns (2010) (26)
Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers (2005) (26)
Distribution and characteristics of betaII tubulin-enriched microtubules in interphase cells. (1999) (25)
Characterization of tau protein present in microtubules and paired helical filaments of Alzheimer's disease patient's brain (1990) (25)
Tau glycation is involved in aggregation of the protein but not in the formation of filaments. (1998) (25)
Microtubule-associated protein 1b, a neuronal marker involved in odontoblast differentiation. (2009) (25)
Triiodothyronine (T3) induces neurite formation and increases synthesis of a protein related to MAP 1B in cultured cells of neuronal origin. (1988) (25)
The role of the VQIVYK peptide in tau protein phosphorylation (2007) (25)
Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus (2018) (25)
Increase in Cytoplasmic Casein Kinase II‐Type Activity Accompanies Neurite Outgrowth After DNA Synthesis Inhibition in NIA‐103 Neuroblastoma Cells (1992) (25)
Alzheimer Center Reina Sofia Foundation: fighting the disease and providing overall solutions. (2010) (25)
The role of tau phosphorylation in transfected COS-1 cells (1995) (24)
Use of Okadaic Acid to Identify Relevant Phosphoepitopes in Pathology: A Focus on Neurodegeneration (2013) (24)
Sodium tungstate decreases the phosphorylation of tau through GSK3 inactivation (2006) (24)
Neuronal Microtubule-associated Protein 2D Is a Dual A-kinase Anchoring Protein Expressed in Rat Ovarian Granulosa Cells* (2004) (24)
Common mechanisms in neurodegeneration (2010) (24)
Phosphorylated tau in neuritic plaques of APPsw/Tauvlw transgenic mice and Alzheimer disease (2008) (24)
Differentiation of neuroblastoma cells correlates with an altered splicing pattern of tau RNA (1992) (24)
Tau phosphorylation in hippocampus results in toxic gain-of-function. (2010) (24)
Regulated expression of p14 (cofactor A) during spermatogenesis. (1999) (24)
Three-dimensional structure of human tubulin chaperone cofactor A. (2002) (24)
Creating a transatlantic research enterprise for preventing Alzheimer's disease (2009) (24)
Ephrin-B1 Promotes Dendrite Outgrowth on Cerebellar Granule Neurons (2002) (23)
Glycogen synthase kinase 3 phosphorylation of different residues in the presence of different factors: Analysis on tau protein (1996) (23)
Mitophagy Failure in APP and Tau Overexpression Model of Alzheimer's Disease. (2019) (23)
[19] Proteolytic modification of tubulin (1986) (23)
Structural and functional domains of tubulin (1985) (23)
Secretion of full-length tau or tau fragments in a cell culture model (2016) (23)
Decreased adult neurogenesis in hibernating Syrian hamster (2016) (22)
MDMA impairs mitochondrial neuronal trafficking in a Tau- and Mitofusin2/Drp1-dependent manner (2014) (22)
The Involvement of Cholinergic Neurons in the Spreading of Tau Pathology (2013) (22)
High level of amyloid precursor protein expression in neurite‐promoting olfactory ensheathing glia (OEG) and OEG‐derived cell lines (2003) (22)
Phospho-Tau Changes in the Human CA1 During Alzheimer’s Disease Progression (2019) (22)
Tau protein, the main component of paired helical filaments. (2006) (21)
Alzheimer's disease: A century of scientific and clinical research (2006) (21)
The Social Component of Environmental Enrichment Is a Pro-neurogenic Stimulus in Adult c57BL6 Female Mice (2019) (21)
Addition of protease inhibitors to culture medium of neuroblastoma cells induces both neurite outgrowth and phosphorylation of microtubule-associated protein MAP-1B. (1991) (21)
Quantitation and characterization of tau factor in porcine tissues. (1986) (21)
Looking for novel functions of tau. (2012) (21)
Sulfo-glycosaminoglycan content affects PHF-tau solubility and allows the identification of different types of PHFs (2002) (20)
Changes in tau phosphorylation in hibernating rodents (2013) (20)
Molecular genetic approaches to microtubule-associated protein function. (2000) (20)
GSK3β Overexpression in Dentate Gyrus Neural Precursor Cells Expands the Progenitor Pool and Enhances Memory Skills* (2016) (20)
Memantine inhibits calpain-mediated truncation of GSK-3 induced by NMDA: implications in Alzheimer's disease. (2009) (20)
Differences in structure and function between human and murine tau. (2019) (20)
Differential expression of microtubule-associated protein 1B phosphorylated isoforms in the adult rat nervous system (1997) (20)
Unusual properties of a cold-labile fraction of Atlantic cod (Gadus morhua) brain microtubules. (1989) (20)
Differences Between Human and Murine Tau at the N-terminal End (2020) (20)
Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1 (2017) (19)
In vitro tau fibrillization: mapping protein regions. (2006) (19)
Isolation of Microtubules and Microtubule Proteins (2008) (19)
Alterations in the nuclear architecture produced by the overexpression of tau protein in neuroblastoma cells. (2013) (19)
Induction of Paclitaxel Resistance by the Kaposi's Sarcoma-Associated Herpesvirus Latent Protein LANA2 (2007) (19)
Inhibition by Aplidine of the aggregation of the prion peptide PrP 106-126 into beta-sheet fibrils. (2003) (19)
Two modes of microtubule-associated protein 1B phosphorylation are differentially regulated during peripheral nerve regeneration (1999) (19)
Altered Ca 2 dependence of synaptosomal plasma membrane Ca 2-ATPase in human brain affected by Alzheimer ’ s disease (2009) (18)
Acetylsalicylic acid decreases tau phosphorylation at serine 422 (2006) (18)
Reelin reverts biochemical, physiological and cognitive alterations in mouse models of Tauopathy (2019) (18)
Tau modifiers as therapeutic targets for Alzheimer's disease. (2005) (17)
Tubulin folding is altered by mutations in a putative GTP binding motif. (1996) (17)
Downregulation of glycogen synthase kinase‐3β (GSK‐3β) protein expression during neuroblastoma IMR‐32 cell differentiation (1999) (17)
Alzheimer's Disease: Advances for a New Century (2012) (17)
Argyrophilic grain pathology as a natural model of tau propagation. (2014) (17)
Distinct X-chromosome SNVs from some sporadic AD samples (2015) (17)
GSK-3β Overexpression Alters the Dendritic Spines of Developmentally Generated Granule Neurons in the Mouse Hippocampal Dentate Gyrus (2017) (17)
Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD (2019) (16)
Differential accumulation of Tau phosphorylated at residues Thr231, Ser262 and Thr205 in hippocampal interneurons and its modulation by Tau mutations (VLW) and amyloid-β peptide (2019) (16)
Differential gene expression analysis of human entorhinal cortex support a possible role of some extracellular matrix proteins in the onset of Alzheimer disease (2010) (16)
Role for the alpha-helix in aberrant protein aggregation. (2005) (16)
Park2-null/tau transgenic mice reveal a functional relationship between parkin and tau. (2008) (16)
Expression of an altered form of tau in Sf9 insect cells results in the assembly of polymers resembling Alzheimer's paired helical filaments (2004) (16)
MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus (2018) (16)
Microtubule-associated protein-2 located in growth regions of rat hippocampal neurons is highly phosphorylated at its proline-rich region (2000) (16)
Overexpression of tau protein in COS-1 cells results in the stabilization of centrosome-independent microtubules and extension of cytoplasmic processes (1994) (16)
Calpain‐mediated truncation of GSK‐3 in post‐mortem brain samples (2009) (16)
Selenomethionine Incorporation into Amyloid Sequences Regulates Fibrillogenesis and Toxicity (2011) (16)
Autoinhibition of TBCB regulates EB1-mediated microtubule dynamics (2012) (16)
AD genetic risk factors and tau spreading (2015) (15)
GSK3α, not GSK3β, drives hippocampal NMDAR‐dependent LTD via tau‐mediated spine anchoring (2020) (15)
Cortistatin as a therapeutic target in inflammation (2007) (15)
Detection of tubulin-binding proteins by an overlay assay. (1988) (15)
Tau regulates the localization and function of End Binding proteins in neuronal cells (2015) (15)
Rearrangement of microtubule associated protein parallels the morphological transformation of neurons from dorsal root ganglion (1989) (15)
The need for better AD animal models (2014) (15)
Microtubule depolymerization and tau phosphorylation. (2013) (15)
Characterization by atomic force microscopy and cryoelectron microscopy of tau polymers assembled in Alzheimer's disease. (2001) (15)
The expression of casein kinase 2α′ and phosphatase 2A activity (1999) (15)
Secretion of full-length Tau or Tau fragments in cell culture models. Propagation of Tau in vivo and in vitro (2018) (14)
Tau and neuron aging. (2013) (14)
Beta-tubulin folding is modulated by the isotype-specific carboxy-terminal domain. (1995) (14)
Treating the lesions, not the disease. (2007) (14)
Overcoming cell death and tau phosphorylation mediated by PI3K-inhibition: a cell assay to measure neuroprotection. (2011) (14)
Coenzyme Q Induces Tau Aggregation, Tau Filaments, and Hirano Bodies (2008) (14)
Microtubule-associated protein, MAP2, is a calcium-binding protein. (1988) (14)
Regulation of EB1/3 proteins by classical MAPs in neurons (2014) (14)
Tau as a molecular marker of development, aging and neurodegenerative disorders. (2008) (14)
Involvement of γ and β Actin Isoforms in Mouse Neuroblastoma Differentiation (1996) (14)
Tau regulates the subcellular localization of calmodulin. (2011) (13)
Financial Intermediation and Entry−Deterrence: A survey (2009) (13)
Retroviral induction of GSK-3β expression blocks the stimulatory action of physical exercise on the maturation of newborn neurons (2016) (13)
Role of phosphorylated MAPIB in neuritogenesis (1994) (13)
Memory and neurogenesis in aging and Alzheimer's disease. (2010) (13)
Memory and exploratory impairment in mice that lack the Park-2 gene and that over-express the human FTDP-17 mutant Tau (2008) (13)
Untold New Beginnings: Adult Hippocampal Neurogenesis and Alzheimer's Disease. (2018) (13)
The removal of the carboxy-terminal region of tubulin favors its vinblastine-induced aggregation into spiral-like structures. (1986) (12)
RETRACTED: γ-Cleavage-Independent Functions of Presenilin, Nicastrin, and Aph-1 Regulate Cell-Junction Organization and Prevent Tau Toxicity In Vivo (2006) (12)
Expression of Tau Produces Aberrant Plasma Membrane Blebbing in Glial Cells Through RhoA-ROCK-Dependent F-Actin Remodeling. (2016) (12)
Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration (2021) (12)
Intra- and extracellular protein interactions with tau. (2010) (12)
A two-hybrid screening of human Tau protein: interactions with Alu-derived domain (2002) (12)
Tau‐positive nuclear indentations in P301S tauopathy mice (2017) (12)
HNK-1 Carrier Glycoproteins Are Decreased in the Alzheimer’s Disease Brain (2015) (12)
Calpain regulates N-terminal interaction of GSK-3β with 14-3-3ζ, p53 and PKB but not with axin (2011) (12)
The expression of casein kinase 2alpha' and phosphatase 2A activity. (1999) (12)
Nuclear localization of β-catenin in adult mouse thalamus correlates with low levels of GSK-3β (1999) (12)
Role of the carboxy terminal region of β tubulin on microtubule dynamics through its interaction with the GTP phosphate binding region (1993) (12)
Tau phosphorylation by glycogen synthase kinase 3β modulates enzyme acetylcholinesterase expression (2020) (12)
A mouse model to study tau pathology related with tau phosphorylation and assembly (2007) (12)
Distinct Functions for Mammalian CLASP1 and -2 During Neurite and Axon Elongation (2019) (12)
Altered levels of microtubule proteins in brains of Alzheimer's disease patients (2004) (11)
βII-tubulin and phospho-tau aggregates in Alzheimer's disease and Pick's disease (2005) (11)
Sodium butyrate induces major morphological changes in C6 glioma cells that are correlated with increased synthesis of a spectrin-like protein. (1989) (11)
A Trypanosoma cruzi monoclonal antibody that recognizes a superficial tubulin-like antigen. (1986) (11)
Hyperphosphorylated tau aggregates in the cortex and hippocampus of transgenic mice with mutant human FTDP-17 Tau and lacking the PARK2 gene (2009) (11)
TNAP Plays a Key Role in Neural Differentiation as well as in Neurodegenerative Disorders. (2015) (11)
Effects of high doses of iodide on thyroid secretion: evidence for the presence of iodinated membrane tubulin. (1985) (11)
The Tau Code (2009) (11)
Factors implicated in determining the structure of zinc tubulin-sheets: lateral tubulin-tubulin interaction is promoted by the presence of zinc. (1981) (11)
Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease (1987) (10)
Crosstalk between axonal classical microtubule-associated proteins and end binding proteins during axon extension: possible implications in neurodegeneration. (2014) (10)
Depletion of catalytic and regulatory subunits of protein kinase CK2 by antisense oligonucleotide treatment of neuroblastoma cells (1994) (10)
Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers (2020) (10)
Our Working Point of View of Tau Protein (2017) (10)
Common antigenic determinants of the tubulin binding domains of the microtubule-associated proteins MAP-2 and tau. (1990) (10)
Epigenetic control of somatostatin and cortistatin expression by β amyloid peptide (2012) (10)
Focal cerebral ischemia induces changes in oligodendrocytic tau isoforms in the damaged area (2020) (10)
A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer’s disease (2021) (10)
[The microtubule-associated protein tau in neurodegenerative diseases. Tauopathies]. (2001) (10)
The role of the cytoskeleton in the morphological changes occurring during neuronal differentiation (1996) (10)
The phosphorylated isoform of microtubule associated protein 1B (MAP1B) is expressed in the visual system of the tench (Tinca tinca, L) during optic nerve regeneration (1998) (10)
Effect of cortistatin on tau phosphorylation at Ser262 site (2008) (10)
Protein kinases involved in the phosphorylation of human tau protein in transfected COS-1 cells. (1996) (10)
Apolipoprotein E4 stimulates sulfation of glycosaminoglycans in neural cells. (2001) (10)
The detection of a spectrin-like protein in Trypanosoma cruzi with a polyclonal antibody. (1988) (10)
Microtubule-associated-protein MAP1 is not implicated in the polymerization of microtubules. (2005) (10)
Maturation Dynamics of the Axon Initial Segment (AIS) of Newborn Dentate Granule Cells in Young Adult C57BL/6J Mice (2019) (10)
Modifications of tau protein during neuronal cell death. (2001) (10)
The influence of aging in one tauopathy: Alzheimer 's disease. (2004) (10)
Tau Aggregation (2022) (10)
OP18/stathmin binds near the C-terminus of tubulin and facilitates GTP binding. (1999) (9)
Does MAP1B bind to tubulin through the interaction of alpha-helices? (1991) (9)
Carboxyl terminal sequences of β-tubulin involved in the interaction of HMW-MAPs. Studies using site-specific antibodies (1994) (9)
Is tau a prion-like protein? (2014) (9)
The Role of Chronic Stress as a Trigger for the Alzheimer Disease Continuum (2020) (9)
Transgenic mouse models with tau pathology to test therapeutic agents for Alzheimer's disease. (2002) (9)
EuroTau: towing scientists to tau without tautology (2017) (8)
The Expression and Localisation of G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channels Is Differentially Altered in the Hippocampus of Two Mouse Models of Alzheimer’s Disease (2021) (8)
A Proteomic Approach for the Involvement of the GAPDH in Alzheimer Disease in the Blood of Moroccan FAD Cases (2014) (8)
BetaII-tubulin and phospho-tau aggregates in Alzheimer's disease and Pick's disease. (2005) (8)
Frontotemporal Dementia-Associated N279K Tau Mutation Localizes at the Nuclear Compartment (2018) (8)
Distribution of the phosphorylated form of microtubule associated protein 1B in the fish visual system during optic nerve regeneration (2001) (8)
Nuclear localization of beta-catenin in adult mouse thalamus correlates with low levels of GSK-3beta. (1999) (8)
Glycogen synthase kinase-3β regulates fractalkine production by altering its trafficking from Golgi to plasma membrane: implications for Alzheimer’s disease (2016) (8)
Control of microtubule polymerization and stability (1995) (8)
Role of phosphorylated MAPlB in neuritogenesis. (1994) (8)
Overexpression of GSK-3β in Adult Tet-OFF GSK-3β Transgenic Mice, and Not During Embryonic or Postnatal Development, Induces Tau Phosphorylation, Neurodegeneration and Learning Deficits (2020) (7)
Validation of Suspected Somatic Single Nucleotide Variations in the Brain of Alzheimer's Disease Patients. (2017) (7)
Peripheral nervous system effects in the PS19 tau transgenic mouse model of tauopathy (2019) (7)
Tauopathy Analysis in P301S Mouse Model of Alzheimer Disease Immunized with DNA and MVA Poxvirus-Based Vaccines Expressing Human Full-Length 4R2N or 3RC Tau Proteins (2020) (7)
Similarities and Differences between Exome Sequences Found in a Variety of Tissues from the Same Individual (2014) (7)
Ultrastructural localization of fructose‐1,6‐bisphosphatase in mouse brain (2011) (7)
Alternative neural circuitry that might be impaired in the development of Alzheimer disease (2015) (7)
The localization of tau proteins on the microtubule surface. (1986) (6)
Variations in brain DNA (2014) (6)
Tau Kinase I Overexpression Induces Dentate Gyrus Degeneration (2010) (6)
Proteolytic modification of tubulin. (1986) (6)
Specific Profile of Tau Isoforms in Argyrophylic Grain Disease (2013) (6)
Phospho-Tau Accumulation and Structural Alterations of the Golgi Apparatus of Cortical Pyramidal Neurons in the P301S Tauopathy Mouse Model (2017) (6)
Alzheimer disease-like cellular phenotype of newborn granule neurons can be reversed in GSK-3β-overexpressing mice (2013) (6)
Tau mRNA 3′UTR-to-CDS ratio is increased in Alzheimer disease (2017) (6)
Is tau a suitable therapeutical target in tauopathies? (2010) (6)
Downregulation of glycogen synthase kinase-3beta (GSK-3beta) protein expression during neuroblastoma IMR-32 cell differentiation. (1999) (5)
Commentary: Genome-wide association study identifies 74 loci associated with educational attainment (2017) (5)
The combined use of limited proteolysis and differential peptide staining for protein characterization. (1986) (5)
crystal structure of Glycogen synthase kinase 3 in complexed with inhibitor (2004) (5)
Tau Protein as a New Regulator of Cellular Prion Protein Transcription (2020) (5)
Collagenous structures present in brain contain epitopes shared by collagen and microtubule-associated protein tau. (1990) (5)
Protein kinases associated with isolated mitotic spindles from mammalian cells: identification of a casein kinase II-like enzyme. (1992) (5)
Motor alterations are reduced in mice lacking the PARK2 gene in the presence of a human FTDP-17 mutant form of four-repeat tau (2008) (5)
Prospects on the origin of Alzheimer's disease. (2010) (5)
Characterization of Alzheimer paired helical filaments by electron microscopy (2005) (5)
Editorial: Shaping the Brain by Neuronal Cytoskeleton: From Development to Disease and Degeneration (2020) (5)
Differential association of the different brain microtubule proteins in different in vitro assembly conditions. (1985) (5)
Incorporation of the high-molecular-weight microtubule-associated protein 2 (MAP2) into microtubules at steady state in vitro. (1980) (5)
The Role of Glycogen Synthase Kinase-3 (GSK-3) in Alzheimer’s Disease (2011) (4)
Microtubule-associated protein tau in murine kidney: role in podocyte architecture (2022) (4)
Animal models for neurodegenerative diseases (2011) (4)
Microtubule dynamics (1990) (4)
The centromere protein CENP-B behaves as a microtubule-associated protein. (1991) (4)
What’s in a Gene? The Outstanding Diversity of MAPT (2022) (4)
Versatile use of rtTA-expressing retroviruses in the study of neurodegeneration (2016) (4)
Protein Biomarkers for the Diagnosis of Alzheimer’s Disease at Different Stages of Neurodegeneration (2020) (4)
DNA polymerase activity, probably DNA polymerase alpha, remains associated to microtubules after successive polymerization cycles. (1980) (4)
Quantitative determination of tubulin and characterization of tubulin forms during development in Drosophila melanogaster. (1985) (4)
Analysis of drug-tubulin interaction by trypsin cleavage: comparison for colchicine, podophyllotoxin, griseofulvin, vinblastine and taxol. (1986) (4)
Excitotoxicity induced by kainic acid provokes glycogen synthase kinase-3 truncation in the hippocampus (2015) (4)
Kidins 220 accumulates with tau in human Alzheimer ’ s disease and related models : modulation of its calpain-processing by GSK 3 b / PP 1 imbalance (2013) (4)
Impaired adult hippocampal neurogenesis in a mouse model for Alzheimer’s disease (2013) (4)
New Beginnings in Alzheimer's Disease: The Most Prevalent Tauopathy. (2018) (4)
p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function (2022) (4)
Long runs of homozygosity are associated with Alzheimer’s disease (2021) (4)
Involvement of gamma and beta actin isoforms in mouse neuroblastoma differentiation. (1996) (4)
GSK-3 β, Adult Neurogenesis and Neurodegeneration (2012) (3)
CHAPTER 5 – The microtubule cytoskeleton in neuronal development and degeneration (1993) (3)
GSK3β overexpression driven by GFAP promoter improves rotarod performance (2019) (3)
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer’s disease and three causality networks of AD: the GR@ACE project (2019) (3)
Centro de Biologia Molecular "Severo Ochoa": a center for basic research into Alzheimer's disease. (2010) (3)
Neuronal nuclear tau and neurodegeneration (2022) (3)
A Possible Role for GSK3 in the Impaired Neurogenesis and Memory Loss Associated with Alzheimer's Disease and Aging (2011) (3)
Neuronal Models for Studying Tau Pathology (2010) (3)
The in vitro formation of recombinant τ polymers (1996) (3)
Muscarinic receptors and Alzheimer’s disease (2011) (3)
Oxidative Damage and Antioxidant Responses in Alzheimer's Disease (2002) (3)
Quantitation of microtubule-associated protein MAP-1B in brain and other tissues. (1989) (3)
Removal of the carboxy terminus of beta-tubulin subunit produces lateral annealing of microtubules with different orientations. (1990) (3)
Comparative measurement by radioimmunoassay of the brain microtubule-associated protein MAP2 (1981) (3)
Profiling of Argonaute-2-loaded microRNAs in a mouse model of frontotemporal dementia with parkinsonism-17. (2018) (3)
Differential phosphorylation of microtubule proteins by ATP and GTP (2004) (3)
Tau triggers tear secretion by interacting with muscarinic acetylcholine receptors in New Zealand white rabbits. (2014) (2)
Alzheimer’s Disease and Empathic Abilities: The Proposed Role of the Cingulate Cortex (2021) (2)
Binding of tau protein to the ends of ex vivo paired helical filaments. (2008) (2)
Calcium binding properties of the beta tubulin subunit from chicken erythrocytes. (1989) (2)
Protocols for Monitoring the Development of Tau Pathology in Alzheimer's Disease. (2016) (2)
Characterization of tubulin isotype-specific antibodies by electrophoretic mobility shift assay. (1998) (2)
human tubulin chaperone cofactor a (2002) (2)
Preface. Alzheimer's disease: advances for a new century. (2013) (2)
ELEVATED ACETYLCHOLINESTERASE LEVELS BY HYPERPHOSPHORYLATED TAU OVEREXPRESSION (2014) (2)
Iodination of proteins on nitrocellulose blotting paper. (1988) (2)
A putative beta-tubulin phosphate-binding motif is involved in lateral microtubule protofilament interactions. (1997) (2)
Phosphorylated microtubule associated protein (MAP1B-Phos) in the retina during regeneration of the fish optic nerve. (1996) (2)
The Carboxyterminal Region of Tubulin Regulates Its Assembly into Microtubules (1986) (2)
Interaction of contractile proteins with DNA. (1978) (2)
Phosphorylation of neuronal microtubule proteins (1988) (2)
IDH-Tau-EGFR triad defines the neovascular landscape of diffuse gliomas by controlling mesenchymal differentiation (2019) (2)
Regulatory aspects of the colchicine interactions with tubulin (2004) (1)
Microtubule Proteins in Neuronal Cells (2018) (1)
Animal Models with Modified Expression of GSK‐3 for the Study of Its Physiology and of Its Implications in Human Pathologies (2006) (1)
Purification of brain microtubule-associated protein MAP1A (1994) (1)
p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model (2022) (1)
Tau protein interaction with M1 and M3 muscarinic receptors (2009) (1)
GSK‐3, a Key Player in Alzheimer's Disease (2006) (1)
Interaction of an Na+-channel toxin, purified from scorpion venom, with micro tubule proteins in vitro (1985) (1)
Fragmentation of the Golgi Apparatus in Neuroblastoma Cells Is Associated with Tau-Induced Ring-Shaped Microtubule Bundles. (2018) (1)
Novel function of Tau in regulating the effects of external stimuli on adult neurogenesis (2016) (1)
Author Correction: Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1 (2018) (1)
Introduction: Intercellular signals and the cytoskeleton (1996) (1)
Editorial: Untangling the Role of Tau in Physiology and Pathology (2020) (1)
Role of polyglycine repeats in the regulation of glycogen synthase kinase activity. (2008) (1)
Inge Grundke-Iqbal: A Legacy of Tau in the Etiology of Alzheimer Disease (1937–2012) (2012) (1)
Human Brain Single Nucleotide Polymorphism: Validation of DNA Sequencing (2018) (1)
Specific Peptide from the Novel W-Tau Isoform Inhibits Tau and Amyloid β Peptide Aggregation In Vitro (2022) (1)
Separate effect of hydroxyurea on the initiation and elongation of DNA synthesis in BHK cells (1978) (1)
Distribution & phosphorylation of the microtubule-associated protein, 1B, in growth cones (1990) (1)
Eladio Viñuela (1937-1999), the molecular biology pioneer in Spain. (1999) (1)
GSK3, tau, neurogenesis and memory loss in Alzheimer's disease (2011) (1)
122 Marine (MA) depsipeptides (DEP) with activity (A) against solid tumours (ST) models (1995) (1)
Identification of the microtubule-associated protein map2 and its binding sites on metaphase chromosomes from cultured cells (2004) (1)
The Role of TGF-β1 in Promoting Microglial Aβ Phagocytosis (2020) (1)
TNAP upregulation is a critical factor in Tauopathies and its blockade ameliorates neurotoxicity and increases life-expectancy (2022) (1)
Functional protection in J20/VLW mice: a model of non-demented with Alzheimer's disease neuropathology. (2021) (1)
The IDH-Tau-EGFR triad defines diffuse glioma pathology by controlling mesenchymal differentiation and neo-vascular fitness (2019) (1)
A calcium binding protein from Drosophila melanogaster which activates cAMP phosphodiesterase: comparison of this protein with porcine brain calmodulin. (1986) (1)
Atypical, non-standard functions of the microtubule associated Tau protein (2017) (1)
10 The Role of Glycogen Synthase Kinase-3 ( GSK-3 ) in Alzheimer ’ s Disease (2012) (0)
GSK‐3β S9A overexpression leads murine hippocampal neural precursors to acquire an astroglial phenotype in vivo (2021) (0)
European Alzheimer Disease Funding (2006) (0)
The role of PKD1 in brain injury: ROS detoxification and neuroprotection (2018) (0)
Oral Sessions: O3-13: Therapeutics: Neuroprotection P549 modulate cell signaling networks. BVR-A interacts with members of the mitogen activated protein kinase family, in particular, ERK1/2, and regulates the expression of oxidative-stress (OS)-responsive genes such as heme-oxygenase-1 or inducible (2013) (0)
Phosphorylation, Microtubule Binding and Aggregation of Tau Protein in Alzheimer's Disease (2002) (0)
[Biochemistry of neoplastic transformation: changes at the molecular level which affect the form and regulation of cell growth. Possible relation between other processes]. (1983) (0)
Preface: Alzheimer’s Disease: New Beginnings (2018) (0)
A 205 kDa protein from non-neuronal cells in culture contains tubulin binding epitopes (1995) (0)
Highlights from the latest articles in Alzheimer\'s disease (2011) (0)
Tissue-nonspecific Alkaline Phosphatase Blockade Ameliorates Behavioural Deficits and Life-expectancy on Tauopathies (2020) (0)
TAU SECRETION AND PROPAGATION (2017) (0)
Boronate-tau mediated uptake in neurons. (2014) (0)
B24 Huntington’s Disease As A Tauopathy (2014) (0)
Inhibition of Glycogen Synthase Kinase 3 (cid:1) During Heart Failure Is Protective Integrative Physiology (2007) (0)
Cognitive and GABAergic protection by hAPPSw,Ind and hTauVLW coexpression: a model of Non-Demented with Alzheimer’s disease Neuropathology (2020) (0)
Structure and Function of Tubulin Regions (2018) (0)
Autosomal Recessive Alzheimer’s disease (arAD): homozygosity mapping of genomic regions containing arAD loci (2020) (0)
Modulation by Phosphorylation of Microtubule Protein Function in the Development of Neural Processes (1994) (0)
PKD1 as a possible therapeutic target in neurodegenerative diseases (2016) (0)
Study of the Function of Microtubule Proteins (1999) (0)
Glycogen synthase kinase-3 b regulates fractalkine production by altering its trafficking from Golgi to plasma membrane : implications for Alzheimer ’ s disease (2016) (0)
P3-318 Tau assembly in vitro. Dissection of the molecule (2006) (0)
Birth of JAD: 20 Years Later (2018) (0)
Interaction between microtubule associated protein MAP2 and pericentromeric DNA. Preferential binding of the protein to a poly dA/dT rich sequence (1984) (0)
Mechanisms of PKD inactivation in excitotoxic brain damage: How PKD activity protects neurons from death (2017) (0)
The First Decade ( 1964-1972 ) Research Article (2018) (0)
Impaired adult hippocampal neurogenesis in Alzheimer?s disease (2013) (0)
“Ecstasy” impairs mitochondrial trafficking in hippocampal neurons by a Tau phosphorylation-dependent mechanism involving GSK3β (2013) (0)
Co-expression of FTDP-17 Human Tau and GSK-3ß (or APPSW) in Transgenic Mice: Induction of Tau Polymerization and Neurodegeneration (2008) (0)
What rendersTAU toxic (2013) (0)
A Possible Role for GSK 3 in the Impaired Neurogenesis and Memory Loss Associated with Alzheimer ’ s Disease and Aging (2011) (0)
757 Posttranslational modifications of tau and the formation of paired helical filaments (1996) (0)
The interaction between a Na+-channel toxin and brain microtubule proteins in vitro. (1986) (0)
Controlled proteolysis of tubulin with subtilisin: structural changes and functional consequences (1984) (0)
Tau phosphorylation and assembly in tauopathies (2005) (0)
PL-02-03 Tau and tauopathies (2006) (0)
OBSERVATION A New Mutation of the Gene , G 303 V , in Early-Onset Familial Progressive Supranuclear Palsy (0)
P3-317 Toxicity of tau in aggregated and non aggregated form (2006) (0)
Role of glycogen synthase kinase-3 in Alzheimer's disease pathogenesis and glycogen (2010) (0)
O2-05-01 Different ways for tau assembly (2004) (0)
S4-03-06 Exploring reversal of Alzheimer’s disease like phenotype in a mouse model with conditional overexpression of GSK-3 (2006) (0)
O2-05-08 Potential protective effects of lithium in Alzheimer’s disease animal models (2006) (0)
Tau contributes to GSK3 induced hippocampal degeneration and learning deficits that are reduced in tau k.o. mice (2009) (0)
TAU TRANSPORT FROM CELL TO CELL (2014) (0)
Tau Phosphorylation as a Therapeutic Target in Alzheimer’s Disease (2016) (0)
Corrigendum to “Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease” (2021) (0)
Phosphorylation and aggregation of tau protein (2000) (0)
B45 TAU-positive nuclear indentations in P301S tauopathy mice (2016) (0)
Dialysis Transplantation The role of the Maillard reaction in other pathologies : Alzheimer ' s disease (2005) (0)
O1-06-02: Extracellular Tau is toxic for neuronal cells (2008) (0)
Coexistence of amyloid-β and Tau hyperphosphorylation rescues cognitive and electrophysiological deficiencies in a mouse model of Alzheimer's disease (2020) (0)
RELATIONSHIP BETWEEN PHOSPHO-TAU ACCUMULATION AND STRUCTURAL ALTERATIONS OF NEURONAL GOLGI APPARATUS IN ALZHEIMER’S DISEASE PATIENTS AND P301S TAUOPATHY MOUSE MODEL (2017) (0)
P3-322 Effect of acetylcholine and cortistatin on tau phosphorylation at Ser 262 site (2006) (0)
Alzheimer's Disease & Parkinsonism (2012) (0)
Tau Exon 10 Inclusion by PrPC through Downregulating GSK3β Activity (2021) (0)

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What Schools Are Affiliated With Jesús Avila?

Jesús Avila is affiliated with the following schools:

University of Milan
University of Cantabria
Autonomous University of Madrid

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