Joachim Frank
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German-born American biophysicist and Nobel laureate
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Joachim Frankphysics Degrees
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Physics
Joachim Frank's Degrees
- PhD Physics Technical University of Munich
Why Is Joachim Frank Influential?
(Suggest an Edit or Addition)According to Wikipedia, Joachim Frank ; born September 12, 1940cryo-EM Life and career Frank was born in Siegen in the borough of Weidenau. After completing his Vordiplom degree in physics at the University of Freiburg and his Diplom under Walter Rollwagen's mentorship at the Ludwig Maximilian University of Munich with the thesis "Untersuchung der Sekundärelektronen-Emission von Gold am Schmelzpunkt" , Frank obtained his Ph.D. from the Technical University of Munich for graduate studies in Walter Hoppe's lab at the Max Planck Institut für Eiweiss- und Lederforschung with the dissertation Untersuchungen von elektronenmikroskopischen Aufnahmen hoher Auflösung mit Bilddifferenz- und Rekonstruktionsverfahren . The thesis explores the use of digital image processing and optical diffraction in the analysis of electron micrographs, and alignment of images using the cross-correlation function.
Joachim Frank's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. (1996) (2132)
- Three-Dimensional Electron Microscopy of Macromolecular Assemblies (2006) (895)
- Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics. (2008) (835)
- A ratchet-like inter-subunit reorganization of the ribosome during translocation (2000) (808)
- Locking and Unlocking of Ribosomal Motions (2003) (592)
- Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State (1996) (534)
- Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions (2001) (519)
- Molecular architecture of the human pre-mRNA 3' processing complex. (2009) (494)
- Three-dimensional reconstruction of single particles embedded in ice. (1992) (490)
- Three‐dimensional reconstruction from a single‐exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli (1987) (486)
- SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs (2008) (486)
- The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles. (1994) (442)
- Outcome of the First Electron Microscopy Validation Task Force Meeting (2012) (422)
- Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization (2007) (416)
- Focused-ion-beam thinning of frozen-hydrated biological specimens for cryo-electron microscopy (2007) (410)
- A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome (1995) (408)
- Structure of the signal recognition particle interacting with the elongation-arrested ribosome (2004) (407)
- Architecture of the Protein-Conducting Channel Associated with the Translating 80S Ribosome (2001) (403)
- Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation (2004) (402)
- Solution Structure of the E. coli 70S Ribosome at 11.5 Å Resolution (2000) (397)
- Use of multivariate statistics in analysing the images of biological macromolecules. (1981) (391)
- Electron tomography : methods for three-dimensional visualization of structures in the cell (2005) (382)
- Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex. (1997) (372)
- Structure of a mammalian ryanodine receptor (2014) (364)
- Computer averaging of electron micrographs of 40S ribosomal subunits. (1981) (360)
- Single-particle imaging of macromolecules by cryo-electron microscopy. (2002) (357)
- The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. (2011) (350)
- Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation. (1998) (337)
- Electron tomography : three-dimensional imaging with the transmission electron microscope (1992) (327)
- Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy (2003) (322)
- Cryo‐EM reveals an active role for aminoacyl‐tRNA in the accommodation process (2002) (312)
- SPIDER—A modular software system for electron image processing (1981) (305)
- Double-tilt electron tomography. (1995) (301)
- EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome (1999) (298)
- Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy (2003) (292)
- Study of the Structural Dynamics of the E. coli 70S Ribosome Using Real-Space Refinement (2003) (291)
- Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle (1994) (289)
- Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome (2004) (288)
- Three-dimensional architecture of the calcium channel/foot structure of sarcoplasmic reticulum (1989) (285)
- The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli (2005) (284)
- Structural Basis for Gating and Activation of RyR1 (2016) (283)
- A 9 Å Resolution X-Ray Crystallographic Map of the Large Ribosomal Subunit (1998) (272)
- Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM (2004) (270)
- Cryo-EM Visualization of a Viral Internal Ribosome Entry Site Bound to Human Ribosomes The IRES Functions as an RNA-Based Translation Factor (2004) (267)
- Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome. (2008) (249)
- Use of multivariate statistics in analysing the images of biological macromolecules (1981) (249)
- Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis (2009) (248)
- A cryo-electron microscopic study of ribosome-bound termination factor RF2 (2003) (234)
- Structure and dynamics of a processive Brownian motor: the translating ribosome. (2010) (225)
- Reconstruction of glutamine synthetase using computer averaging. (1978) (219)
- Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy. (2000) (216)
- Direct Visualization of A-, P-, and E-Site Transfer RNAs in the Escherichia coli Ribosome (1996) (209)
- Automated acquisition of cryo-electron micrographs for single particle reconstruction on an FEI Tecnai electron microscope. (2005) (205)
- The process of mRNA–tRNA translocation (2007) (204)
- Structures of modified eEF2·80S ribosome complexes reveal the role of GTP hydrolysis in translocation (2007) (202)
- The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. (2001) (202)
- Electron Tomography (1992) (201)
- Structure of mammalian eIF3 in the context of the 43S preinitiation complex (2015) (194)
- Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29 (2013) (193)
- Trajectories of the ribosome as a Brownian nanomachine (2014) (192)
- Escherichia coli 70 S ribosome at 15 A resolution by cryo-electron microscopy: localization of fMet-tRNAfMet and fitting of L1 protein. (1998) (191)
- Preparation of macromolecular complexes for cryo-electron microscopy (2007) (189)
- Signal-to-noise ratio of electron micrographs obtained by cross correlation (1975) (185)
- An Unbiased cDNA Library Prepared from Isolated Aplysia Sensory Neuron Processes Is Enriched for Cytoskeletal and Translational mRNAs (2003) (179)
- Visualization of protein S1 within the 30S ribosomal subunit and its interaction with messenger RNA (2001) (173)
- Three-dimensional reconstruction with contrast transfer function correction from energy-filtered cryoelectron micrographs: procedure and application to the 70S Escherichia coli ribosome. (1997) (173)
- The internal compartmentation of rat‐liver mitochondria: Tomographic study using the high‐voltage transmission electron microscope (1994) (171)
- Comprehensive molecular structure of the eukaryotic ribosome. (2009) (169)
- A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation. (2006) (168)
- Correspondence analysis of aligned images of biological particles. (1982) (167)
- Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit (2013) (165)
- Averaging of low exposure electron micrographs of non-periodic objects. (1975) (163)
- Channel opening and gating mechanism in AMPA-subtype glutamate receptors (2017) (162)
- Structure of the E. coli protein-conducting channel bound to a translating ribosome (2005) (162)
- Motif detection in quantum noise-limited electron micrographs by cross-correlation. (1977) (161)
- A common-lines based method for determining orientations for N > 3 particle projections simultaneously. (1996) (160)
- Three-dimensional reconstruction of the 70S Escherichia coli ribosome in ice: the distribution of ribosomal RNA (1991) (159)
- Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications (2004) (154)
- Visualization of Trna Movements on the Escherichia coli 70s Ribosome during the Elongation Cycle (2000) (154)
- Visualizing tmRNA Entry into a Stalled Ribosome (2003) (151)
- Computer processing of electron microscope images (1980) (146)
- Structural characterization of a dynein motor domain. (1998) (145)
- Three‐dimensional cryo‐electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 Å resolution (2000) (145)
- Location of translational initiation factor IF3 on the small ribosomal subunit. (1999) (145)
- RF3 Induces Ribosomal Conformational Changes Responsible for Dissociation of Class I Release Factors (2007) (143)
- Continuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM. (2016) (141)
- Ultrastructure of the calcium release channel of sarcoplasmic reticulum (1988) (141)
- Focused ion beam milling of vitreous water: prospects for an alternative to cryo‐ultramicrotomy of frozen‐hydrated biological samples (2006) (137)
- Ribosome dynamics: insights from atomic structure modeling into cryo-electron microscopy maps. (2006) (136)
- Estimation of variance in single-particle reconstruction using the bootstrap technique. (2006) (135)
- Single-particle reconstruction of biological macromolecules in electron microscopy – 30 years (2009) (134)
- Towards high-resolution three-dimensional imaging of native mammalian tissue: electron tomography of frozen-hydrated rat liver sections. (2006) (132)
- High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome (2013) (132)
- Structure of the E. coli protein-conducting channel bound to a translating ribosome (2006) (128)
- Advances in the field of single-particle cryo-electron microscopy over the last decade (2017) (119)
- Classification of macromolecular assemblies studied as ‘single particles’ (1990) (119)
- A NEW 3‐D RECONSTRUCTION SCHEME APPLIED TO THE 50S RIBOSOMAL SUBUNIT OF E. COLI (1986) (116)
- Electron tomographic analysis of frozen-hydrated tissue sections. (2002) (113)
- Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. (2005) (113)
- Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation. (2001) (112)
- A model of the translational apparatus based on a three-dimensional reconstruction of the Escherichia coli ribosome. (1995) (112)
- Multivariate statistical analysis of ribosome electron micrographs. L and R lateral views of the 40 S subunit from HeLa cells. (1982) (106)
- Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu (2009) (106)
- Three-dimensional reconstruction of the Escherichia coli 30 S ribosomal subunit in ice. (1996) (105)
- Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy (2016) (105)
- Three-dimensional imaging of biological complexity. (2002) (105)
- Structure of the STRA6 receptor for retinol uptake (2016) (105)
- The Role of Correlation Techniques in Computer Image Processing (1980) (105)
- Mechanism of Tetracycline Resistance by Ribosomal Protection Protein Tet(O) (2013) (105)
- Recent progress in the crystallographic studies of photosystem II. (2010) (104)
- The role of tRNA as a molecular spring in decoding, accommodation, and peptidyl transfer (2005) (101)
- Electron microscopy and computer image averaging of ice-embedded large ribosomal subunits from Escherichia coli. (1988) (100)
- Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset. (2004) (95)
- Three‐dimensional structure of the large ribosomal subunit from Escherichia coli. (1987) (95)
- Structural characterization of mRNA-tRNA translocation intermediates (2012) (94)
- The ABC-F protein EttA gates ribosome entry into the translation elongation cycle (2014) (92)
- Structure and activity of lipid bilayer within a membrane-protein transporter (2018) (91)
- A glycan gate controls opening of the SARS-CoV-2 spike protein (2021) (91)
- Determination of signal-to-noise ratios and spectral SNRs in cryo-EM low-dose imaging of molecules. (2009) (90)
- Ryanodine Receptor Structure and Function in Health and Disease. (2018) (89)
- A glycan gate controls opening of the SARS-CoV-2 spike protein (2021) (89)
- Effect of Buffer Conditions on the Position of tRNA on the 70 S Ribosome As Visualized by Cryoelectron Microscopy* (1999) (88)
- Interaction of the G' domain of elongation factor G and the C-terminal domain of ribosomal protein L7/L12 during translocation as revealed by cryo-EM. (2005) (88)
- Three-dimensional structure of the yeast ribosome. (1998) (88)
- Time-resolved cryo-electron microscopy: Recent progress. (2017) (88)
- Domain motions of EF-G bound to the 70S ribosome: insights from a hand-shaking between multi-resolution structures. (2000) (86)
- Alignment by Cross-Correlation (1992) (86)
- Direct structural localization of two toxin-recognition sites on an ACh receptor protein (1982) (85)
- Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements. (2006) (84)
- Movement of the decoding region of the 16 S ribosomal RNA accompanies tRNA translocation. (2000) (84)
- Structure of the colcemid-treated PtK1 kinetochore outer plate as determined by high voltage electron microscopic tomography (1993) (82)
- A Fast and Effective Microfluidic Spraying-Plunging Method for High-Resolution Single-Particle Cryo-EM. (2017) (79)
- Three-dimensional reconstruction of the 30 S ribosomal subunit from randomly oriented particles. (1984) (78)
- Integrity of the P-site is probed during maturation of the 60S ribosomal subunit (2012) (78)
- Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA (1999) (77)
- Automatic Particle Picking From Electron Micrographs (1995) (76)
- Three-dimensional cryoelectron microscopy of ribosomes. (2000) (76)
- Cryo-EM of the native structure of the calcium release channel/ryanodine receptor from sarcoplasmic reticulum. (1992) (76)
- Automatic selection of molecular images from electron micrographs (1983) (75)
- Eukaryotic initiation factor 3 does not prevent association through physical blockage of the ribosomal subunit-subunit interface. (1992) (75)
- Three-dimensional tomographic reconstruction in high voltage electron microscopy (1987) (74)
- Localization of the ribosomal protection protein Tet(O) on the ribosome and the mechanism of tetracycline resistance. (2001) (74)
- Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes (2017) (73)
- Late steps in bacterial translation initiation visualized using time-resolved cryo-EM (2019) (72)
- A marker-free alignment method for electron tomography. (1995) (72)
- Interactions of the release factor RF1 with the ribosome as revealed by cryo-EM. (2006) (71)
- Characterization of the nuclear export adaptor protein Nmd3 in association with the 60S ribosomal subunit (2010) (71)
- A study of heavy-light atom discrimination in bright-field electron microscopy using the computer. (1972) (71)
- Structural dynamics of ribosome subunit association studied by mixing-spraying time-resolved cryogenic electron microscopy. (2015) (69)
- Cryo-EM visualization of transfer messenger RNA with two SmpBs in a stalled ribosome (2006) (69)
- Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP (2013) (69)
- Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy (2003) (68)
- Definition and estimation of resolution in single-particle reconstructions. (2010) (68)
- EttA regulates translation by binding to the ribosomal E site and restricting ribosome-tRNA dynamics (2014) (68)
- Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis (2017) (64)
- The structure of the stalk surface layer of a brine pond microorganism: correlation averaging applied to a double layered lattice structure (1985) (64)
- Structure and structural variations of the Escherichia coli 30 S ribosomal subunit as revealed by three-dimensional cryo-electron microscopy. (1999) (63)
- Tomographic three-dimensional reconstruction of cilia ultrastructure from thick sections. (1986) (63)
- The structure of the 80S ribosome from Trypanosoma cruzi reveals unique rRNA components. (2005) (62)
- Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication (2003) (62)
- Fast automatic particle picking from cryo-electron micrographs using a locally normalized cross-correlation function: a case study. (2004) (62)
- Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex (2012) (62)
- Native 3D structure of eukaryotic 80s ribosome: morphological homology with E. coli 70S ribosome (1996) (62)
- Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit (2016) (61)
- Computer Processing of Electron Micrographs (1973) (60)
- Outcome of a workshop on archiving structural models of biological macromolecules. (2006) (59)
- Co- and post-translational translocation through the protein-conducting channel: analogous mechanisms at work? (2006) (59)
- Key Intermediates in Ribosome Recycling Visualized by Time-Resolved Cryoelectron Microscopy. (2016) (57)
- On the correction of the contrast transfer function in biological electron microscopy (1995) (57)
- Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits. (2007) (57)
- Retrieving functional pathways of biomolecules from single-particle snapshots (2020) (56)
- Electron Microscopy of Macromolecular Assemblies (1996) (56)
- Structural insights on the translation initiation complex: ghosts of a universal initiation complex (2007) (55)
- Fast 3D motif search of EM density maps using a locally normalized cross-correlation function. (2003) (55)
- Cryo‐electron microscopy as an investigative tool: the ribosome as an example (2001) (55)
- Electron microscopy of functional ribosome complexes. (2003) (54)
- Structural details of membrane-bound acetylcholine receptor from Tropedo marmorata. (1980) (53)
- Unsupervised classification of single particles by cluster tracking in multi-dimensional space. (2007) (53)
- Dynamical features of the Plasmodium falciparum ribosome during translation (2015) (52)
- Automated particle picking for low-contrast macromolecules in cryo-electron microscopy. (2014) (52)
- Conformational variability in Escherichia coli 70S ribosome as revealed by 3D cryo-electron microscopy. (1999) (51)
- The mechanism of translation (2017) (51)
- Low-dose automated electron tomography: a recent implementation. (1997) (51)
- Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G (2015) (51)
- Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM (2008) (51)
- Localization and dynamic behavior of ribosomal protein L30e (2005) (50)
- Studying ribosome structure by electron microscopy and computer-image processing. (1988) (50)
- Structural insights into cognate versus near‐cognate discrimination during decoding (2011) (50)
- Three-dimensional reconstruction of single particles negatively stained or in vitreous ice. (1992) (50)
- Structural and functional evidence for multiple channel complexes in the outer membrane of Neurospora crassa mitochondria. (1983) (49)
- THREE DIMENSIONAL RECONSTRUCTION WITH CONTRAST TRANSFER COMPENSATION FROM DEFOCUS SERIES (1997) (49)
- Structure of human GABAB receptor in an inactive state (2020) (48)
- Three-Dimensional Analysis of Mitochondrial Crista Ultrastructure in a Patient with Leigh Syndrome by In Situ Cryoelectron Tomography (2018) (48)
- Structural studies of the translational apparatus. (1999) (48)
- Image analysis of single macromolecules. (1989) (47)
- Herbicide binding and thermal stability of photosystem II isolated from Thermosynechococcus elongatus. (2006) (47)
- The ribosome--a macromolecular machine par excellence. (2000) (46)
- Visualization of macromolecular complexes using cryo-electron microscopy with FEI Tecnai transmission electron microscopes (2008) (46)
- Representation of three‐dimensionally reconstructed objects in electron microscopy by surfaces of equal density (1984) (46)
- Approach to the direct intramolecular localization of antigenic determinants in Androctonus australis hemocyanin with monoclonal antibodies by molecular immunoelectron microscopy. (1985) (46)
- Direct localization of the tRNA--anticodon interaction site on the Escherichia coli 30 S ribosomal subunit by electron microscopy and computerized image averaging. (1988) (45)
- The ribosome and the mechanism of protein synthesis (2006) (45)
- Negative staining characteristics of arrays of mitochondrial pore protein: use of correspondence analysis to classify different staining patterns. (1984) (45)
- An approach to examining model dependence in EM reconstructions using cross-validation. (2003) (45)
- A 360° single‐axis tilt stage for the high‐voltage electron microscope (1992) (44)
- Time‐dependent insulin oligomer reaction pathway prior to fibril formation: Cooling and seeding (2009) (44)
- Structure of the Channels in the Outer Mitochondrial Membrane: Electron Microscopic Studies of the Periodic Arrays Induced by Phospholipase a(2) Treatment of the Neurospora membrane. (1986) (44)
- A new non-crystallographic image-processing technique reveals the architecture of ribosomes. (1988) (43)
- Quaternary structure of Octopus vulgaris hemocyanin. Three-dimensional reconstruction from frozen-hydrated specimens and intramolecular location of functional units Ove and Ovb. (1994) (42)
- Functional conformations of the L11-ribosomal RNA complex revealed by correlative analysis of cryo-EM and molecular dynamics simulations. (2006) (42)
- Electron tomographic and other approaches for imaging molecular machines (2001) (42)
- Transfer RNA in the hybrid P/E state: Correlating molecular dynamics simulations with cryo-EM data (2007) (41)
- Particle-verification for single-particle, reference-based reconstruction using multivariate data analysis and classification. (2008) (41)
- Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM (2009) (41)
- Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation (2011) (41)
- Three-Dimensional Reconstruction of Nonperiodic Macromolecular Assemblies from Electron Micrographs (1986) (41)
- The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy (2018) (41)
- A twisted tRNA intermediate sets the threshold for decoding. (2003) (41)
- Approaches to large-scale structures. (1995) (41)
- Three-dimensional reconstruction of the ribosome from Escherichia coli. (1989) (40)
- Two promising future developments of cryo-EM: capturing short-lived states and mapping a continuum of states of a macromolecule. (2016) (39)
- Introduction: Principles of Electron Tomography (2007) (39)
- A method for differentiating proteins from nucleic acids in intermediate-resolution density maps: cryo-electron microscopy defines the quaternary structure of the Escherichia coli 70S ribosome. (2000) (39)
- Visualizing the transfer-messenger RNA as the ribosome resumes translation (2010) (38)
- Flavones inhibit the hexameric replicative helicase RepA. (2001) (38)
- Toward an understanding of the structural basis of translation (2003) (38)
- Interaction kinetics of tetramethylrhodamine transferrin with human transferrin receptor studied by fluorescence correlation spectroscopy. (1999) (38)
- Dimeric arrangement and structure of the membrane‐bound acetylcholine receptor studied by electron microscopy. (1982) (38)
- Fuzzy sets‐based classification of electron microscopy images of biological macromolecules with an application to ribosomal particles (1990) (38)
- Size determination of cyanobacterial and higher plant photosystem II by gel permeation chromatography, light scattering, and ultracentrifugation. (2005) (38)
- 3 Structure and Function of the Eukaryotic Ribosome and Elongation Factors (2007) (37)
- Ratchet-like movements between the two ribosomal subunits: their implications in elongation factor recognition and tRNA translocation. (2001) (37)
- Scaffolding as an Organizing Principle in Trans-translation (2007) (37)
- Particle picking by segmentation: a comparative study with SPIDER-based manual particle picking. (2005) (36)
- Molecular dynamics of EF‐G during translocation (2011) (36)
- Three-dimensional Architecture of Human α2-Macroglobulin Transformed with Methylamine (1993) (35)
- Investigation of the 50 S ribosomal subunit by electron microscopy and image analysis. (1985) (35)
- Three-dimensional Architecture of Human α2-Macroglobulin Transformed with Methylamine (1993) (35)
- Measurement of neuronal surface area using high-voltage electron microscope tomography (1992) (35)
- Classification by bootstrapping in single particle methods (2010) (34)
- Estimation of variance distribution in three-dimensional reconstruction. I. Theory. (1995) (34)
- Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1 (2013) (34)
- Reference-free particle selection enhanced with semi-supervised machine learning for cryo-electron microscopy. (2011) (34)
- Computer-averaged views of the 70 S monosome from Escherichia coli. (1986) (34)
- Efficient estimation of three-dimensional covariance and its application in the analysis of heterogeneous samples in cryo-electron microscopy. (2015) (33)
- Resolution in Electron Tomography (2007) (33)
- Exploration of parameters in cryo-EM leading to an improved density map of the E. coli ribosome. (2008) (33)
- Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel (2020) (33)
- Time-resolved fluorescence investigations of the interaction of the voltage-sensitive probe RH421 with lipid membranes and proteins. (1995) (33)
- Femtosecond dark-field imaging with an X-ray free electron laser. (2012) (33)
- Direct three-dimensional localization and positive identification of RNA helices within the ribosome by means of genetic tagging and cryo-electron microscopy. (1999) (32)
- Time-Resolved Cryo-electron Microscopy Using a Microfluidic Chip. (2018) (32)
- Architecture of Limulus polyphemus hemocyanin. (1982) (32)
- Three-dimensional reconstruction of native Androctonus australis hemocyanin. (1990) (32)
- Generalized single-particle cryo-EM--a historical perspective. (2016) (32)
- Folding kinetics and structure of OEP16. (2004) (31)
- Direct localization of the tRNAs within the elongating ribosome by means of neutron scattering (proton-spin contrast-variation). (1997) (31)
- Single-Particle Reconstruction of Biological Molecules-Story in a Sample (Nobel Lecture). (2018) (31)
- Three-dimensional reconstruction of Androctonus australis hemocyanin labeled with a monoclonal Fab fragment. (1995) (31)
- Affinity grid-based cryo-EM of PKC binding to RACK1 on the ribosome. (2013) (30)
- Averages of glutamine synthetase molecules as obtained with various skin and electron dose conditions. (1980) (30)
- Intermediate states during mRNA-tRNA translocation. (2012) (30)
- The characterization of structural variations within a crystal field. (1988) (30)
- Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells (2020) (30)
- New Insights into Ribosome Structure and Function. (2018) (29)
- CTF Challenge: Result summary. (2015) (29)
- Identification of Changing Ribosome Protein Compositions using Mass Spectrometry (2018) (29)
- Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex (2019) (29)
- Visualization of the eEF2-80S ribosome transition-state complex by cryo-electron microscopy. (2008) (29)
- Three-dimensional structure of the mammalian cytoplasmic ribosome. (1990) (29)
- SPIRE: the SPIDER reconstruction engine. (2007) (28)
- The Jigsaw Puzzle of mRNA Translation Initiation in Eukaryotes: A Decade of Structures Unraveling the Mechanics of the Process. (2018) (28)
- Ultrastructure of chromatin. II. Three-dimensional reconstruction of isolated fibers. (1991) (28)
- New Opportunities Created by Single-Particle Cryo-EM: The Mapping of Conformational Space (2018) (28)
- Protein crystallization screening through scattering techniques (1995) (28)
- Variations of the three-dimensional structure of the Escherichia coli ribosome in the range of overlap views. An application of the methods of multicone and local single-cone three-dimensional reconstruction. (1989) (27)
- Structure of frozen-hydrated triad junctions: a case study in motif searching inside tomograms. (2009) (27)
- A clarification of the terms used in comparing semi-automated particle selection algorithms in cryo-EM. (2011) (27)
- The Envelope of Electron Microscopic Transfer Functions for Partially Coherent Illumination (2018) (26)
- Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A (2018) (26)
- Tinkerbell--a tool for interactive segmentation of 3D data. (1997) (26)
- Three-dimensional immunoelectron microscopy of scorpion hemocyanin labeled with a monoclonal Fab fragment. (1993) (25)
- The movement of tRNA through the ribosome. (1998) (25)
- Determination of the ribosome structure to a resolution of 2.5 Å by single‐particle cryo‐EM (2017) (25)
- Three-dimensional reconstruction of mammalian 40 S ribosomal subunit. (1989) (25)
- Thermally induced aggregation of human transferrin receptor studied by light-scattering techniques. (1999) (24)
- Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis. (2004) (24)
- A model for co‐translational translocation: Ribosome‐regulated nascent polypeptide translocation at the protein‐conducting channel (2006) (24)
- Use of nonlinear mapping in multivariate image analysis of molecule projections. (1985) (24)
- Comparison of fungal 80 S ribosomes by cryo-EM reveals diversity in structure and conformation of rRNA expansion segments. (2007) (23)
- Molecular machines in biology : workshop of the cell (2011) (23)
- Methods for Averaging of Single Molecules and Lattice-Fragments (1980) (23)
- The ribosome at higher resolution--the donut takes shape. (1997) (23)
- Molding atomic structures into intermediate-resolution cryo-EM density maps of ribosomal complexes using real-space refinement. (2005) (22)
- Story in a sample-the potential (and limitations) of cryo-electron microscopy applied to molecular machines. (2013) (22)
- Hepatitis C Virus IRES RNA—Induced Changes in the Conformation of the 40S (2001) (22)
- Propagation of Conformational Coordinates Across Angular Space in Mapping the Continuum of States from Cryo-EM Data by Manifold Embedding (2020) (21)
- Cytochrome c binds to lipid domains in arrays of mitochondrial outer membrane channels. (1987) (21)
- Interaction of the fluorescent probe RH421 with ribulose-1,5-bisphosphate carboxylase/oxygenase and with Na+,K(+)-ATPase membrane fragments. (1996) (21)
- The ribosome-structure and functional ligand-binding experiments using cryo-electron microscopy. (1998) (21)
- Effect of excitation on the host–guest equilibrium constants of cyclodextrin complexes (1995) (21)
- Einige Erfahrungen mit der rechnerischen Analyse und Synthese von elektronenmikroskopischen Bildern hoher Auflösung (1970) (20)
- Three-dimensional reconstruction of a complex of human alpha 2-macroglobulin with monomaleimido Nanogold (Au1.4nm) embedded in ice. (1992) (20)
- In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors (2020) (20)
- Controlled focusing and stigmating in the conventional and scanning transmission electron microscope (1975) (20)
- Studies of Elongation Factor G-Dependent tRNA Translocation by Three-Dimensional Cryo-Electron Microscopy (2000) (20)
- Three-dimensional structure of 50 S Escherichia coli ribosomal subunits depleted of proteins L7/L12. (1988) (20)
- Computational Methods for Three-Dimensional Microscopy Reconstruction (2014) (19)
- Three-dimensional reconstruction of chromatin fibers. (1983) (19)
- The translation elongation cycle—capturing multiple states by cryo-electron microscopy (2017) (19)
- Haloarcula marismortui 50S subunit-complementarity of electron microscopy and X-Ray crystallographic information. (1999) (18)
- Molecular Machines in Biology (2011) (18)
- Interaction of fluorescence labeled single-stranded DNA with hexameric DNA-helicase RepA: a photon and fluorescence correlation spectroscopy study. (2001) (18)
- Electron microscopic stains as probes of the surface charge of mitochondrial outer membrane channels. (1984) (18)
- The layered organization of nucleosomes in 30 nm chromatin fibers (2004) (17)
- Intermolecular localization of epitopes within an oligomeric protein by immunoelectron microscopy and image processing (1988) (17)
- Image Analysis In Electron Microscopy (1979) (17)
- Three-dimensional reconstruction of mammalian 40 S ribosomal subunit embedded in ice. (1995) (17)
- Anwendung des Bilddifferenzverfahrens auf die Untersuchung von Strukturänderungen dünner Kohlefolien bei Elektronenbestrahlung (1970) (16)
- Identification of ions in experimental electrostatic potential maps (2018) (16)
- The role of multivariate image analysis in solving the architecture of the Limulus polyphemus hemocyanin molecule. (1984) (16)
- Effects of divalent metal ions and chelators on the structure of outer mitochondrial membranes from neurospora crassa. (1982) (15)
- A refined quaternary structure of Androctonus australis Hemocyanin. (2005) (15)
- Cryo-Electron Microscopy of the Translational Apparatus: Experimental Evidence for the Paths of mRNA, tRNA, and the Polypeptide Chain (2000) (15)
- Ribosomal dynamics explored by cryo-electron microscopy. (2001) (15)
- Animation of the dynamical events of the elongation cycle based on cryoelectron microscopy of functional complexes of the ribosome. (1999) (14)
- Shape changes and polarization of cells migrating through tissue. A high-voltage electron microscope and computer graphics study of serial thick sections. (1985) (14)
- Patch averaging of electron images of GP3*I crystals with variable thickness. (1992) (14)
- The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs (2019) (13)
- In vitro reconstitution and biophysical characterization of OEP16, an outer envelope pore protein of pea chloroplasts. (2000) (13)
- From DNA to proteins via the ribosome: Structural insights into the workings of the translation machinery (2010) (13)
- Three-dimensional structure of mitochondrial outer-membrane channels from fungus and liver (1984) (13)
- The parallelization of SPIDER on distributed-memory computers using MPI. (2007) (12)
- Quantitative Connection between Ensemble Thermodynamics and Single-Molecule Kinetics: A Case Study Using Cryogenic Electron Microscopy and Single-Molecule Fluorescence Resonance Energy Transfer Investigations of the Ribosome. (2015) (12)
- The group II intron ribonucleoprotein precursor is a large, loosely packed structure (2010) (12)
- Whither Ribosome Structure and Dynamics Research? (A Perspective). (2016) (12)
- Nanobubble-controlled nanofluidic transport (2020) (12)
- Flopping polypeptide chains and Suleika's subtle imperfections: analysis of variations in the electron micrograph of a purple membrane crystal. (1993) (12)
- Three-dimensional imaging techniques in electron microscopy. (1989) (12)
- Conformational Dynamics and Energy Landscapes of Ligand Binding in RyR1 (2017) (12)
- Microcalorimetric determination of the reaction enthalpy changes associated with the carboxylase and oxygenase reactions catalysed by ribulose 1,5-bisphosphate carboxylase/oxygenase (RUBISCO) (2000) (11)
- Thermodynamics and kinetics of sugar phosphate binding to D-ribulose 1,5-bisphosphate carboxylase/oxygenase (RUBISCO) (1998) (11)
- Three-dimensional matching of macromolecular structures obtained from electron microscopy: an application to the 70S and 50S E. coli ribosomal particles. (1988) (11)
- Estimation of variance distribution in three-dimensional reconstruction. II. Applications. (1995) (11)
- DNA helicase RepA: cooperative ATPase activity and binding of nucleotides. (2000) (11)
- The Ribosome Comes Alive. (2010) (10)
- POLARIS: path of least action analysis on energy landscapes (2019) (10)
- A library of RNA bridges (2006) (10)
- The active 80S ribosome-Sec61 complex. (2001) (10)
- Low-Dose Electron Microscopy of Individual Biological Macromolecules (1980) (10)
- Quantitative Characterization of Domain Motions in Molecular Machines. (2017) (10)
- Interrelatedness of 5S RNA sequences investigated by correspondence analysis (2005) (10)
- Interactions of Trimeric Purine Nucleoside Phosphorylases with Ground State Analogues—Calorimetric and Fluorimetric Studies (2003) (9)
- Structure of Ribosomes and Their Components by Advanced Techniques of Electron Microscopy and Computer Image Analysis (1986) (9)
- Three-dimensional reconstruction of cytochrome oxidase vesicle crystals prepared by cholate solubilization. (1985) (9)
- OPTIMAL USE OF IMAGE INFORMATION USING SIGNAL DETECTION AND AVERAGING TECHNIQUES (1978) (9)
- Two-Dimensional Averaging Techniques (1996) (9)
- Intramolecular localization of epitopes within an oligomeric protein by immunoelectron microscopy and image processing. (1988) (9)
- Particle migration analysis in iterative classification of cryo-EM single-particle data. (2014) (8)
- New strategies for determining ribosomal subunit structure from electron micrographs by single particle averaging methods. (1986) (8)
- Statistical significance of molecule projections by single particle averaging (1984) (8)
- Alignment, classification, and three-dimensional reconstruction of single particles embedded in ice. (1992) (8)
- Temperature induced crystallization transition in aqueous solutions of ß-cyclodextrin, heptakis(2,6-di-O-methyl)-ß-cyclodextrin (DIMEB), and heptakis(2,3,6-tri-O-methyl)-ß-cyclodextrin (TRIMEB) studied by differential scanning calorimetry (2002) (8)
- Selektion von Standard-Software : Kriterien und Methoden zur Beurteilung und Auswahl von Software-Produkten (1976) (8)
- Gesundheit, Krankheit : das Elend der Medizin (1985) (8)
- Comments on the interpretation of triplet excited-state decay data for the determination of the equilibrium constants in host–guest cyclodextrin complexes (1995) (7)
- Displaying 3D data on RNA secondary structures: coloRNA. (2007) (7)
- Tomographic Three-Dimensional Reconstruction of Patch-Clamped Membranes Imaged With The High-Voltage Electron Microscope (1990) (7)
- Methods for studying the dynamic behavior of biological macromolecules. (1982) (7)
- Simulation of cryo-EM ensembles from atomic models of molecules exhibiting continuous conformations (2019) (7)
- Colloidal properties of human transferrin receptor in detergent free solution. (2000) (7)
- Visualization of a group II intron in the 23S rRNA of a stable ribosome. (2006) (7)
- A Time‐Resolved Cryo‐EM Study of Saccharomyces cerevisiae 80S Ribosome Protein Composition in Response to a Change in Carbon Source (2020) (7)
- Addendum to "reconstruction of glutamine synthetase using computer averaging". (1979) (7)
- Image reconstruction of low and high dose micrographs of negatively stained glutamine synthetase (1978) (7)
- Three‐Dimensional Reconstruction of Human α2‐Macroglobulin and Refinement of the Localization of Thiol Ester Bonds with Monomaleimido Nanogold a (1994) (7)
- An assay for local quality in cryo-electron micrographs of single particles. (2002) (7)
- Feasibility of Focused Ion Beam Milling for Preparation of TEM Specimens of Biological Material Embedded in Vitreous Ice (2005) (7)
- Multivariate Statistical Analysis and Classification of Images (1996) (6)
- chapter 16 Three-Dimensional Reconstruction of Single Molecules (1981) (6)
- Localization of lipoyl-bearing domains in the alpha-ketoglutarate dehydrogenase multienzyme complex. (1984) (6)
- Single-Particle Cryo-Electron Microscopy: The Path Toward Atomic Resolution/ Selected Papers of Joachim Frank with Commentaries (2018) (6)
- Three-dimensional reconstruction of single molecules. (1981) (6)
- On the damage done to the structure of the Thermoplasma acidophilum proteasome by electron radiation (2018) (6)
- Effect of succinylation on images of negatively stained arrays of mitochondrial outer membrane channels. (1986) (6)
- KINETICS AND EQUILIBRIUM BINDING OF THE DYES TNS AND RH421 TO RIBULOSE 1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE (RUBISCO) (1997) (6)
- Influence of allosteric effectors on the kinetics and equilibrium binding of phosphoenolpyruvate (PEP) to phosphoenolpyruvate carboxylase (PEPC) from Zea mays. (2001) (6)
- Focused Ion Beam (FIB) Preparation Methods for 3-D Biological Cryo-TEM (2006) (6)
- Bilddifferenzverfahren in der Elektronenmikroskopie (1969) (6)
- tmRNA on its way through the ribosome (2011) (6)
- Interaction of different oligomeric states of hexameric DNA‐helicase RepA with single‐stranded DNA studied by analytical ultracentrifugation (2000) (6)
- Structure and activity of lipid bilayer within a membrane-protein transporter. (2018) (5)
- Multivariate Data Analysis and Classification of Images (2006) (5)
- Kinetics and equilibrium binding of phosphoenolpyruvate to phosphoenolpyruvate carboxylase from Zea mays (1999) (5)
- chapter 12 Introduction (1981) (5)
- Structural insights into cognate vs. near-cognate discrimination during decoding. (2014) (5)
- Use of SPIDER and SPIRE in image reconstruction (2012) (5)
- Three-dimensional architecture of human alpha 2-macroglobulin transformed with methylamine. (1993) (5)
- Three-Dimensional Reconstruction (1996) (5)
- Analysis of the irregular planar distribution of proteins in membranes (1985) (5)
- Identification of changing ribosome protein compositions using cryo-EM and mass spectrometry (2018) (5)
- A 360 degrees single-axis tilt stage for the high-voltage electron microscope. (1992) (5)
- Quantitative Analysis in Iterative Classification Schemes for Cryo-EM Application (2014) (5)
- Gewerkschaften in Europa (1977) (5)
- Masks for prescreening of molecule projections (1984) (5)
- Mapping of Antigenic Determinants in Androctonus Australis Hemocyanin: Preliminary Results (1986) (4)
- Time-resolved imaging of macromolecular processes and interactions. (2004) (4)
- Correlation averaging: Lattice separation and resolution assessment (1986) (4)
- "Just in Time": The Role of Cryo-Electron Microscopy in Combating Recent Pandemics. (2021) (4)
- Problems with the transorientation hypothesis. (2002) (4)
- Use of the Zernike Phase Plate for Electron Tomography of Frozen-Hydrated Specimens (2005) (4)
- Molecular Machines in Biology: Visualization of Molecular Machines by Cryo-Electron Microscopy (2011) (4)
- Recovery of Conformational Continuum From Single-Particle Cryo-EM Images: Optimization of ManifoldEM Informed by Ground Truth (2022) (4)
- Faraday communications. Application of iodine-laser temperature jump to an irreversible enzyme reaction. Reaction of ascorbic acid with hydrogen peroxide catalysed by peroxidase (1994) (4)
- On the Use of POCS for Restoring the “Missing Wedge” in Electron Tomography (1990) (3)
- Untersuchungen von elektronenmikroskopischen Aufnahmen hoher Auflösung mit Bilddifferenz- und Rekonstruktionsverfahren (1970) (3)
- High-resolution Cryo-EM Structure of the Trypanosoma brucei Ribosome: A Case Study (2014) (3)
- Major rearrangements in the 70 S ribosomal 3 D structure caused by a conformational switch in 16 S ribosomal RNA (2013) (3)
- EXPLORING THE DYNAMICS OF SUPRAMOLECULAR MACHINES WITH CRYO-ELECTRON MICROSCOPY (2014) (3)
- Corrigendum to “Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset” [J. Struct. Biol. 147 (2004) 283–290] (2004) (3)
- Profiling structured beams using injected aerosols (2012) (3)
- Ribosomal Dynamics: Intrinsic Instability of a Molecular Machine (2009) (3)
- Real-time structural dynamics of late steps in bacterial translation initiation visualized using time-resolved cryogenic electron microscopy (2018) (3)
- Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3-Tif6-Lsg1 Complex (2017) (3)
- Measurement of radioactive tracer microsphere blood flow with NaI (Tl)- and Ge-well type detectors (1982) (3)
- FIB Milling of Frozen-hydrated Cells and Tissue for TEM Cryo-Tomography (2008) (2)
- Ribosome dynamics: Progress in the characterization of mRNA-tRNA translocation by cryo-electron microscopy (2011) (2)
- Electron Tomographic Comparison of Frozen-Hydrated and Freeze-Substituted Sections of High-Pressure Frozen Rat-Liver Tissue (2003) (2)
- Image Averaging of Membrane-Bound Acetylcholine Receptor from Torpedo marmorata (1980) (2)
- Interaction Networks of Ribosomal Expansion Segments in Kinetoplastids. (2021) (2)
- Application of Tomographic 3D Reconstruction Methods To A Diverse Range of Biological Preparations (1990) (2)
- Critical Role for Saccharomyces cerevisiae Asc1p in Translational Initiation at Elevated Temperatures (2018) (2)
- Recovery of conformational continuum from single-particle cryo-EM data: Optimization of ManifoldEM informed by ground-truth studies (2021) (2)
- THE DYNAMICS OF THE RIBOSOME AS INFERRED BY CRYO-EM: INDUCED AND SELF-ORCANIZED MOTIONS (2004) (2)
- The Mechanism of aa-tRNA Entry into the Ribosome (2009) (2)
- Kinetics and molecular modelling of ligand binding to ribulose 1, 5‐bisphosphate carboxylase/oxygenase (RUBISCO) (1996) (2)
- Cryo-Electron Microscopy (Cryo-EM) Structure of a Cap-Independent Translational Enhancer of the Turnip Crinkle Virus (TCV) Bound to the Eukaryotic Ribosome (2012) (2)
- Cryo Electron Microscopy & Reconstruction (2012) (2)
- Geometric machine learning informed by ground truth: Recovery of conformational continuum from single-particle cryo-EM data of biomolecules (2021) (2)
- Contributions of single-particle cryoelectron microscopy toward fighting COVID-19 (2021) (2)
- Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes) (2014) (2)
- Found in Translation: Collection of Original Articles on Single-Particle Reconstruction and the Structural Basis of Protein Synthesis (2014) (2)
- Unterstützte Testausführung für automatisierte Fertigungsanlagen durch Verknüpfung von Testmanagement und E-CAD sowie Einbindung von Augmented Reality (2018) (2)
- Ribosome Structure and Shape (2001) (2)
- Fully Automated Particle Selection and Verification in Single-Particle Cryo-EM (2014) (2)
- In-situ observation of the formation of laser-induced periodic surface structures with extreme spatial and temporal resolution (2022) (2)
- Digital image enhancement for transmission electron microscopy (1978) (1)
- Multivariate Statistical Analysis and Tomographic Processing of Helical Objects (2002) (1)
- USE OF THE IMAGE DIFFERENCE METHOD FOR INVESTIGATION OF STRUCTURAL CHANGES OF THIN CARBON FOILS BY ELECTRON IRRADIATION. (1970) (1)
- Cover Picture: Recent Progress in the Crystallographic Studies of Photosystem II (ChemPhysChem 6/2010) (2010) (1)
- 33 High-resolution cryo-EM structure of the Trypanosoma brucei 80S: a unique eukaryotic ribosome (2013) (1)
- Critical Movements of a Single Diphthamide Residue of Eukaryotic Elongation Factor 2 Monitored by Cryo-EM (2007) (1)
- Detection of Object Movement in the Optical Diffractograms of Electron Micrographs (2018) (1)
- Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues (2005) (1)
- Fidelity of bacterial translation initiation: a stochastic kinetic model (2018) (1)
- Naturalistische Studie zur Wirksamkeit stationärer psychodynamischer Psychotherapie (2021) (1)
- Studying Kinetics by Counting Particles in Time-Resolved Cryo-EM (2019) (1)
- cryo-electron microscopy structure of the Trypanosoma brucei 80S ribosome (2013) (1)
- Schelte für den Boten der schlechten Nachricht. Gedanken eines Journalisten zur Debatte über die Berichterstattung zum Germanwings-Absturz (2015) (1)
- High-resolution cryo-EM structure of Trypanosoma brucei 80 S : A unique eukaryotic ribosome (2012) (1)
- Three-dimensional reconstruction at the molecular level (1992) (1)
- Single Particle Reconstruction by Electron Microscopy (2003) (1)
- Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA (2021) (1)
- Molecular Machines in Biology: Contents (2011) (1)
- Methods for three-dimensional reconstruction of cellular components within a thick section (1986) (1)
- Functional Site Determinations in Three Dimensions on Eukaryotic and Eubacterial Ribosomes (1993) (1)
- Quantitative three-dimensional reconstruction. Introduction. (1981) (1)
- New Avenues in Electron Microscopy of Transmembranous Biomolecular Assemblies (1987) (0)
- Estimation of the 3D Variance-Covariance Map in Cryo-Electron Microscopy (2010) (0)
- Coordinates of the N-terminal domain of ribosomal protein L11,C-terminal domain of ribosomal protein L7/L12 and a portion of the G' domain of elongation factor G, as fitted into cryo-em map of an Escherichia coli 70S*EF-G*GDP*fusidic acid complex (2005) (0)
- 1999 XIII International Biophysics Congress 19-24 September 1999 New Delhi Abstracts Suppl (2016) (0)
- Coordinates of RRF and EF-G fitted into Cryo-EM map of the 50S subunit bound with both EF-G (GDPNP) and RRF (2005) (0)
- Structural basis for gating and activation of RyR1 (30 uM Ca2+ dataset, all particles) (2016) (0)
- Domain-wise fitting of the crystal structure of T.thermophilus EF-G into the low resolution map of the release complex.Puromycin.EFG.GDPNP of E.coli 70S ribosome. (2003) (0)
- Coordinates of S12, L11 proteins and P-tRNA, from the 70S X-ray structure aligned to the 70S Cryo-EM map of E.coli ribosome (2003) (0)
- Advances in High Resolution Cryo-EM Studies: the Quartenary Structure of the 70S E.Coli Ribosome Revealed at 11.5Å Resolution. (2000) (0)
- Interactions of Trimeric Purine Nucleoside Phosphorylases with Ground State Analogues — Calorimetric and Fluorimetric Studies (2004) (0)
- The Ribosome – Ligand Interactions and Dynamics as Inferred by Cryo-EM (2002) (0)
- Tecnai F 30 Helium Microscope : Initial Results and Observations (2002) (0)
- Entwicklung einer korrosions- und verschleißbeständigen Eisenbasisschicht (2015) (0)
- The First Atomic Model of the Transfer-Messenger RNA in the Resume State (2011) (0)
- Cryo-EM structure of ryanodine receptor/Calstabin-2 complex (2014) (0)
- GluA2 bound to antagonist ZK and GSG1L in digitonin, state 1 (2017) (0)
- Structure of the 50S subunit of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1143 (2006) (0)
- Structure of the 40S rRNA and proteins and P/E tRNA for eukaryotic ribosome based on cryo-EM map of Thermomyces lanuginosus ribosome at 8.9A resolution (2009) (0)
- Protocols – 10 year Commentary-Advances in the field of cryo-electron microscopy over the last decade : A Commentary (2017) (0)
- The P-site and P/E-site tRNA structures fitted to P/I site codon. (2005) (0)
- Cryo-electron Microscopy of the Ribosome: Methods of Fitting, and Inference of Dynamics (2005) (0)
- Structure of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1056 (2014) (0)
- Coordinates of the A/T site tRNA model fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome (2003) (0)
- Structure of the 30S subunit of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1056 (2006) (0)
- Opening a new window into the cell with super-resolution imaging and in situ cryo-electron tomography (2020) (0)
- Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome (2002) (0)
- Toward a Cryo-Em Structure of the Ribosome Bound to BipA (2012) (0)
- Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP cryo-EM reconstruction (2007) (0)
- Activated GluA2 complex bound to glutamate, cyclothiazide, and STZ in digitonin (2017) (0)
- Elektrisch beheizter Hochtemperaturgassensor (1999) (0)
- Interpretation of Three-Dimensional Images of Macromolecules (1996) (0)
- Coordinates of 16S and 23S rRNAs fitted into the cryo-EM map of RF1-bound termination complex (2009) (0)
- The Structural Basis for Initiation Factor 2 Activation during Translation Initiation (2018) (0)
- Coordinates of 16S and 23S rRNAs fitted into the cryo-EM map of RF3-bound termination complex (2009) (0)
- GluA2-2xGSG1L bound to L-Quisqualate (2017) (0)
- Lipid Bilayer Structure in Native Cell Membrane Nanoparticles of Multidrug Exporter ACRB (2018) (0)
- Functional Interpretation of the Cryo-Electron Microscopy Map of the 30S Ribosomal Subunit from Escherichia coli (2000) (0)
- Enhanced Projections in Electron Micrographs of 40S Ribosomal Subunits from HeLa Cells (1981) (0)
- Coordinates of 16S and 23S rRNAs fitted into the cryo-EM map of EF-G-bound translocation complex (2009) (0)
- Protein backbone tracing and macromolecular motion by cryo-EM and single particle analysis (2008) (0)
- Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) (2019) (0)
- Reconstruction of the acto‐myosin interface: new approaches and new results (1999) (0)
- What's in the Black Box? - A Perspective on Software in Cryo-Electron Microscopy. (2021) (0)
- Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome (2004) (0)
- Exmaple for an Application: Calcium Release Channel (1996) (0)
- Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. This file, 1S1H, Contains 40S subunit. The 60S Ribosomal Subunit Is In File 1S1I. (2004) (0)
- Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 2) (2019) (0)
- Resistiver Galliumoxid-Wasserstoffsensor (2001) (0)
- Binding position of ribosome recycling factor (RRF) on the E. coli 70S ribosome (2004) (0)
- RF2 accommodated state bound 70S complex at long incubation time (2019) (0)
- Structural insights into aminoacyl-tRNA delivery by EF-Tu and translocation by EF-G (2008) (0)
- Conformational Heterogeneity of Macromolecules Analyzed by Cryo-Electron Microscopy (2006) (0)
- Coordinates of L11 with 58nts of 23S rRNA fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome (2003) (0)
- Separate Fitting of the Anticodon Loop Region of tRNA (nucleotide 26-42) in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome (2002) (0)
- Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction (2007) (0)
- Structure of the 50S subunit of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1056 (2006) (0)
- Cryo-Electron Microscopy Training at the Wadsworth Center (2000) (0)
- Localization of L11 protein on the E. coli ribosome and elucidation of its direct role in EF-G-dependent tRNA translocation (2000) (0)
- Tetracycline resistance protein Tet(O) bound to the ribosome (2013) (0)
- Transfer RNA in the hybrid P/E state (2007) (0)
- Structural insights into cognate vs. near-cognate discrimination during decoding. This entry contains the small subunit of a ribosome programmed with a near-cognate codon, A/T-site tRNA, P-site tRNA, mRNA and EF-Tu (2011) (0)
- Tomographic Reconstructions of 0.25 μm-Thick Serial Sections of a Mammalian Kinetochore (1990) (0)
- Structure of the 80S rRNA and proteins and P/E tRNA for eukaryotic ribosome based on cryo-EM map of Thermomyces lanuginosus ribosome at 8.9A resolution (2014) (0)
- GluA2-1xGSG1L bound to ZK (2017) (0)
- Modified E. coli tmRNA in the resume state with the tRNA-like domain in the ribosomal P site interacting with the SmpB (2010) (0)
- EF-Tu.kirromycin coordinates fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome (2003) (0)
- GluA2-2xGSG1L bound to ZK (2017) (0)
- The Cryo-EM Structure of the Ribosome Bound to BipA (2014) (0)
- Coordinates of tmRNA, SmpB, EF-Tu and h44 fitted into Cryo-EM map of the 70S ribosome and tmRNA complex (2005) (0)
- Structure of rabbit RyR1 (ryanodine dataset, all particles) (2016) (0)
- Dynamic structure of L11-rRNA complex (MDII) (2006) (0)
- Structural characterization of mRNA-tRNA translocation intermediates (30S ribosome of class 4a of the six classes) (2012) (0)
- A Time-Resolved CRYO-EM Study of Ribosome Subunit Association by Mixing-Spraying (2014) (0)
- Front Cover: Identification of Changing Ribosome Protein Compositions using Mass Spectrometry (2018) (0)
- Efficient Strategy for Processing Single Particle Data from a Cryo-EM Exposure Series (2005) (0)
- Cryo-em Study Of Trna Hybrid States Stabilized By Viomycin (2009) (0)
- Cryo-em Study Of Trna Hybrid States Stabilized By Viomycin (2009) (0)
- Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1 (2019) (0)
- Normal mode-based flexible fitted coordinates of a non-translocating SecYEG protein-conducting channel into the cryo-EM map of a SecYEG-nascent chain-70S ribosome complex from E. coli (2005) (0)
- GluA2-0xGSG1L bound to ZK (2017) (0)
- GluA2 bound to GSG1L in digitonin, state 1 (2017) (0)
- Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome (2003) (0)
- Structure of rabbit RyR1 (ryanodine dataset, class 2) (2016) (0)
- The Structure of The 70S E. Coli Rtoosome In Ice (1990) (0)
- GluA2 bound to GSG1L in digitonin, state 2 (2017) (0)
- Structural insights into cognate vs. near-cognate discrimination during decoding. This entry contains the large subunit of a ribosome programmed with a near-cognate codon. (2011) (0)
- Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP:sordarin cryo-EM reconstruction (2007) (0)
- Coordinates of 16S and 23S rRNAs fitted into the cryo-EM map of a pretranslocation complex (2009) (0)
- Structure of rabbit RyR1 (Caffeine/ATP/EGTA dataset, all particles) (2016) (0)
- Structure of rabbit RyR1 (ryanodine dataset, class 1) (2016) (0)
- Conformation of EF-G during translocation (2011) (0)
- RF2 pre-accommodated state bound Release complex 70S at 24ms (2019) (0)
- Elucidating Ribosomal Translocation with Internal Coordinate Flexible Fitting (2014) (0)
- Fitting of L11 protein and elongation factor G (domain G' and V) in the cryo-em map of E. coli 70S ribosome bound with EF-G and GMPPCP, a nonhydrolysable GTP analog (2001) (0)
- Visualization of ribosomal conformational changes during the initial selection process of decoding using cryo-EM (2007) (0)
- Components of the control 70S ribosome to provide reference for the RRF binding site (2004) (0)
- Merging data from cryo-EM and X-ray crystallography to reveal biomolecular function (2008) (0)
- Coordinates of RRF fitted into Cryo-EM map of the 70S post-termination complex (2005) (0)
- The Dynamics of Translation Studied by Cryo-Electron Microscopy (2000) (0)
- Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 1) (2019) (0)
- Visualizing tmRNA after its accommodation in the Ribosome (2009) (0)
- Faculty Opinions recommendation of Structures of the human and Drosophila 80S ribosome. (2013) (0)
- Visualizing tmRNA after its accommodation in the Ribosome (2009) (0)
- Cryo-EM structure of GluA2-2xSTZ complex at 7.8 Angstrom resolution (2016) (0)
- GluA2 bound to antagonist ZK and GSG1L in digitonin, state 2 (2017) (0)
- Fitting of L11 protein in the low resolution cryo-EM map of E.coli 70S ribosome (2001) (0)
- Cryo-EM Study of the Ribosome-Bound Release Factor 1 (2005) (0)
- Cryo-EM map of the CSFV IRES in complex with the small ribosomal 40S subunit and DHX29 (2013) (0)
- Cryo-EM structure of GluA2-0xSTZ at 8.7 Angstrom resolution (2016) (0)
- Three-dimensional analysis of mitochondrial crista ultrastructure in a Leigh Syndrome patient by in situ cryo-electron tomography (2018) (0)
- [Image differentiation procedures in electron microscopy]. (1969) (0)
- A scripting language approach to control software for cryo-electron microscopy (2002) (0)
- Determination of Resolution in Electron Tomography (2006) (0)
- Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment) (2020) (0)
- Author response: Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1 (2013) (0)
- Structure of cGMP-unbound F403V/V407A mutant TAX-4 reconstituted in lipid nanodiscs (2020) (0)
- Coordinates of S12, SH44, LH69 and SRL separately fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome (2003) (0)
- Two steps of resume and what next (2011) (0)
- Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3 Complex (2017) (0)
- A CRYO-EM Structure of a Minimal Translation Initiation System: Deletion in Self-Sufficient IRES Prevents Translocation (2014) (0)
- Classification of Projections in Single Particle Electron Microscopy using Common Line Similarity Measure (2011) (0)
- Fitting of the eEF2 crystal structure into the cryo-EM density map of the eEF2.80S.AlF4-.GDP complex (2008) (0)
- CLASSIFICATION BY BOOTSTRAPPING IN SINGLE PARTICLE METHODS Hstau (2010) (0)
- Fitting of L11 protein and elongation factor G (EF-G) in the cryo-em map of e. coli 70S ribosome bound with EF-G, GDP and fusidic acid (2001) (0)
- Decoding Center & Peptidyl transferase center from the X-ray structure of the Thermus thermophilus 70S ribosome, aligned to the low resolution Cryo-EM map of E.coli 70S Ribosome (2003) (0)
- Structure of rabbit RyR1 (Caffeine/ATP/Ca2+ dataset, class 1&2) (2016) (0)
- RF1 accommodated state bound Release complex 70S at long incubation time point (2019) (0)
- Cryo‐EM Studies of the Translocation Process (2006) (0)
- Computergestützte Interaktionsvorrichtung für Sehbehinderte und Blinde (1996) (0)
- Wachstumsmarkt Telekommunikation — Controlling für Netzbetreiber (1995) (0)
- Einzelpartikel-Rekonstruktion biologischer Moleküle - Geschichte in einer Probe (Nobel-Aufsatz) (2018) (0)
- Psychische Struktur und Mentalisierungsfähigkeit bei stationären depressiven Patienten im Langzeitverlauf (0)
- Corrigendum to “A clarification of the terms used in comparing semi-automated particle selection algorithms in cryo-EM” [J. Struct. Biol. 175 (2011) 348–352] (2015) (0)
- Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1 (2006) (0)
- Structure of cGMP-unbound WT TAX-4 reconstituted in lipid nanodiscs (2020) (0)
- Hydraulische In-situ-Bodensanierung (1991) (0)
- „Diese abscheulichen Bilder“ Kirche, Gewalt und Sexualität in den Augen der Öffentlichkeit (2013) (0)
- dynamic structures of the L11-rRNA complex (MDI) (2006) (0)
- Signal- und Gegensprechanlage für die Haustechnik (1995) (0)
- 70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA (2018) (0)
- Cryo-EM structure of GluA2-1xSTZ complex at 6.4 Angstrom resolution (2016) (0)
- Sensor und Verfahren zur selektiven, separaten Detektion von CO und/oder CH¶4¶ mit einen solchen neuen Sensor (1998) (0)
- Wer braucht heute noch die kirchliche Presse? Zehn (Chef-)Redakteure von Tageszeitungen zu den Perspektiven der katholischen Publizistik (2011) (0)
- Development of cryogenic correlated light electron microscopy methods to study mechanisms of intracellular trafficking and their relationships to the secretory pathway (2016) (0)
- Figure 19.8.3.1 (2012) (0)
- Artificial Spin Ice Inspired Computation using Nanomagnets (0)
- 70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2) (2018) (0)
- Structural and functional significance of the N-terminus of Cx 26 gap junction channels (2008) (0)
- RF1 pre-accommodated 70S complex at 24 ms (2019) (0)
- Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1143 (2014) (0)
- A cold look at transcription. (2002) (0)
- Structure of the 60S proteins for eukaryotic ribosome based on cryo-EM map of Thermomyces lanuginosus ribosome at 8.9A resolution (2009) (0)
- Advances in image processing for electron microscopy: Part I. (1988) (0)
- Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P/E-tRNA (2015) (0)
- Structural characterization of mRNA-tRNA translocation intermediates (50S ribosome of class2 of the six classes) (2012) (0)
- Cryo-EM structure of the mammalian eRF1-eRF3-associated termination complex (2012) (0)
- Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit (2003) (0)
- 50S subunit with EF-G(GDPNP) and RRF bound (2008) (0)
- FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME (2000) (0)
- Structure and Mechanism of Eukaryotic Translation Initiation (2016) (0)
- 70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3) (2018) (0)
- Coordinates of the A-site tRNA model fitted into the cryo-EM map of 70S ribosome in the pre-translocational state (2003) (0)
- [Structure of the murein sacculus of Spirillum serpens. Quantitative electron microscopy studies at high resolution]. (1969) (0)
- Structure of rabbit RyR1 (ryanodine dataset, class 3) (2016) (0)
- Model of tRNA(Leu)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM (2008) (0)
- Analysis Of Ribosomal Dynamics As Revealed By Cryo-EM And Flexible Fitting (2009) (0)
- Docking of the modified RF3 X-ray structure into cryo-EM map of E.coli 70S ribosome bound with RF3 (2007) (0)
- TRNA POSITIONS DURING THE ELONGATION CYCLE (2000) (0)
- Three-Dimensional Reconstruction of Native Androctonus Australis Hemocyanin (1990) (0)
- Abstracts (1968) (0)
- Cryo-EM structure of GluA2 bound to antagonist ZK200775 at 6.8 Angstrom resolution (2016) (0)
- Ternary complex-bound E.coli 70S ribosome. This entry consists of the 30S subunit, tRNAs and the ternary complex. (2009) (0)
- Structure of rabbit RyR1 (EGTA-only dataset, all particles) (2016) (0)
- Functional Study of the Ryanodine Receptor Type 1 using Cryo-Electron Microscopy (2017) (0)
- New challenges to image processing posed by cryo-Electron microscopy of single particles (1991) (0)
- Structure of rabbit RyR1 (EGTA-only dataset, class 1) (2016) (0)
- Use of Focused Ion Beam Milling for Preparation of Frozen-Hydrated Specimens for TEM Tomography (2007) (0)
- Orbweaver: A New Graphical User Interface for Particle Selection in Single-Particle Reconstruction with Cryo-Em (2011) (0)
- Ternary complex-bound E.coli 70S ribosome. (2014) (0)
- 70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4) (2018) (0)
- Structure of the 30S subunit of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1143 (2006) (0)
- Electron Tomography of Frozen-Hydrated Sections (2002) (0)
- Coordinates of S12, L11 proteins and E-site tRNA from 70S crystal structure separately fitted into the Cryo-EM map of E.coli 70S.EF-G.GDPNP complex. The atomic coordinates originally from the E-site tRNA were fitted in the position of the hybrid P/E-site tRNA. (2003) (0)
- Single-particle reconstructionof biological macromolecules inelectronmicroscopy ^ 30 years (2009) (0)
- Ternary complex-bound E.coli 70S ribosome. This entry consists of the 50S subunit. (2009) (0)
- Author Correction: Structure of human GABAB receptor in an inactive state (2020) (0)
- RF1 accommodated 70S complex at 60 ms (2019) (0)
- Structure of tmRNA-(SmpB)2 complex as inferred from cryo-EM (2007) (0)
- APE-SITE TRNA, THEORETICAL MODEL (1997) (0)
- Substrate and Inhibitor Binding to Ribulose 1,5-Bisphosphate Carboxylase / Oxygenase (Rubisco) (1995) (0)
- Single-Particle Cryo-Electron Microscopy (2019) (0)
- On Bootstrap Techniques For Classifying Projections in Single Particle Electron Microscopy (2010) (0)
- Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. (2014) (0)
- Faculty Opinions recommendation of 2.8-Å Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania. (2017) (0)
- Coordinates of L11 with 58nts of 23S rRNA fitted into the cryo-EM map of the 70S ribosome (2003) (0)
- What HVEM tomographic reconstruction methods tell us about biological ultrastructure: Present and future developments (1991) (0)
- Model of Phe-tRNA(Phe) in the ribosomal pre-accommodated state revealed by cryo-EM (2008) (0)
- Docking of the modified RF2 X-ray structure into the Low Resolution Cryo-EM map of RF2 E.coli 70S Ribosome (2003) (0)
- IF2, IF1, and tRNA fitted to cryo-EM data OF E. COLI 70S initiation complex (2005) (0)
- 70S ribosome-EF-Tu H84A complex with GppNHp (2018) (0)
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