Joan Massagué
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Professor of Cancer biology
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Joan Massaguéphilosophy Degrees
Philosophy
#1067
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#2014
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Logic
#136
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#319
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Biology Philosophy
Joan Massagué's Degrees
- PhD Biochemistry University of Barcelona
Why Is Joan Massagué Influential?
(Suggest an Edit or Addition)According to Wikipedia, Joan Massagué , is a Spanish biologist and the current director of the Sloan Kettering Institute at Memorial Sloan Kettering Cancer Center. He is also an internationally recognized leader in the study of both cancer metastasis and growth factors that regulate cell behavior, as well as a professor at the Weill Cornell Graduate School of Medical Sciences.
Joan Massagué's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- TGF-beta signal transduction. (1998) (7603)
- Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus (2003) (4921)
- Cancer Metastasis: Building a Framework (2006) (3874)
- Mechanisms of TGF-beta signaling from cell membrane to the nucleus. (2003) (3188)
- TGFβ in Cancer (2008) (3076)
- Genes that mediate breast cancer metastasis to lung (2005) (2922)
- The transforming growth factor-beta family. (1990) (2765)
- A multigenic program mediating breast cancer metastasis to bone. (2003) (2521)
- Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. (1986) (2449)
- Smad transcription factors. (2005) (2407)
- TGFβ signalling in context (2012) (2394)
- Metastasis: from dissemination to organ-specific colonization (2009) (2369)
- Cloning of p27 Kip1 , a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals (1994) (2268)
- Mechanism of activation of the TGF-β receptor (1994) (2136)
- Transcriptional control by the TGF‐β/Smad signaling system (2000) (2032)
- p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. (1994) (1928)
- Endogenous human microRNAs that suppress breast cancer metastasis (2008) (1889)
- Controlling TGF-β signaling (2000) (1752)
- TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders (2000) (1676)
- Genes that mediate breast cancer metastasis to the brain (2009) (1647)
- How cells read TGF-beta signals. (2000) (1609)
- Epithelial-Mesenchymal Transitions Twist in Development and Metastasis (2004) (1515)
- TGFβ signals through a heteromeric protein kinase receptor complex (1992) (1430)
- Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex (1995) (1411)
- Metastatic colonization by circulating tumour cells (2016) (1280)
- Tumor Self-Seeding by Circulating Cancer Cells (2009) (1183)
- How cells read TGF-β signals (2000) (1161)
- G1 cell-cycle control and cancer (2004) (1153)
- TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. (2005) (1086)
- Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. (1995) (1060)
- A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras. (1999) (1053)
- Integration of Smad and Forkhead Pathways in the Control of Neuroepithelial and Glioblastoma Cell Proliferation (2004) (1038)
- TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. (1999) (1025)
- Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer (2003) (1016)
- lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin (1994) (1006)
- TGFbeta signaling in growth control, cancer, and heritable disorders. (2000) (1002)
- Transforming Growth Factor-β Signaling in Immunity and Cancer. (2019) (929)
- Crystal structure of the p27Kip1 cyclin-dependent-kinase inibitor bound to the cyclin A–Cdk2 complex (1996) (926)
- Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. (1995) (908)
- TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4 (2008) (897)
- A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis (2012) (893)
- Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways (1996) (891)
- TGF- SIGNAL TRANSDUCTION (1998) (885)
- Controlling TGF-beta signaling. (2000) (882)
- Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation. (2012) (848)
- Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells. (1992) (846)
- Betaglycan presents ligand to the TGFβ signaling receptor (1993) (841)
- Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation (1990) (839)
- Transforming growth factor-beta. (1992) (802)
- TGFβ Signaling: Receptors, Transducers, and Mad Proteins (1996) (793)
- Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27 Kip1 ) of cyclin-dependent kinase 4 activation (1994) (792)
- Genetic determinants of cancer metastasis (2007) (784)
- Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. (2003) (781)
- Guidelines and definitions for research on epithelial–mesenchymal transition (2020) (778)
- Mechanism of activation of the TGF-beta receptor. (1994) (756)
- Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs (2011) (755)
- Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor. (1998) (753)
- Crystal Structure of a Smad MH1 Domain Bound to DNA Insights on DNA Binding in TGF-β Signaling (1998) (749)
- Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway (1999) (737)
- A human Mad protein acting as a BMP-regulated transcriptional activator (1996) (717)
- Mediators of vascular remodelling co-opted for sequential steps in lung metastasis (2007) (703)
- Membrane-anchored growth factors. (1993) (703)
- Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. (2005) (702)
- The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors (1987) (694)
- Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-beta. (1987) (689)
- Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways (2009) (688)
- The logic of TGFβ signaling (2006) (680)
- GS domain mutations that constitutively activate T beta R‐I, the downstream signaling component in the TGF‐beta receptor complex. (1995) (678)
- Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors (1993) (667)
- The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor. (1982) (653)
- The TGF-β family of growth and differentiation factors (1987) (647)
- Latent bone metastasis in breast cancer tied to Src-dependent survival signals. (2009) (647)
- Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs (1995) (637)
- Regulation of cell adhesion receptors by transforming growth factor-beta. Concomitant regulation of integrins that share a common beta 1 subunit. (1989) (631)
- Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis (2014) (624)
- Beyond tumorigenesis: cancer stem cells in metastasis (2007) (615)
- The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. (1997) (609)
- Repression of p15INK4b expression by Myc through association with Miz-1 (2001) (602)
- Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1 (1995) (602)
- Roles of TGFβ in metastasis (2009) (600)
- Receptors for the TGF-β family (1992) (595)
- Metastatic stem cells: sources, niches, and vital pathways. (2014) (591)
- A Smad Transcriptional Corepressor (1999) (572)
- Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta. (1993) (565)
- Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system (1991) (565)
- Molecular basis of metastasis. (2008) (565)
- Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer (2016) (563)
- Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. (2005) (549)
- WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis (2009) (545)
- A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. (2003) (539)
- Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development. (1997) (532)
- Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage. (1997) (530)
- Type beta transforming growth factor is an inhibitor of myogenic differentiation. (1986) (525)
- Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT (2016) (515)
- E2F4/5 and p107 as Smad Cofactors Linking the TGFβ Receptor to c-myc Repression (2002) (510)
- TGF beta signals through a heteromeric protein kinase receptor complex. (1992) (508)
- The TGF-β family and its composite receptors (1994) (506)
- TGFβ influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b (2001) (495)
- The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction (1989) (492)
- Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs. (2011) (492)
- Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors (1992) (485)
- A structural basis for mutational inactivation of the tumour suppressor Smad4 (1997) (479)
- Transforming growth factor β signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis (2003) (477)
- Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes. (1997) (472)
- Cell adhesion protein receptors as targets for transforming growth factor-β action (1987) (470)
- Contextual determinants of TGFβ action in development, immunity and cancer (2018) (461)
- Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells. (1983) (461)
- The logic of TGFbeta signaling. (2006) (455)
- OAZ Uses Distinct DNA- and Protein-Binding Zinc Fingers in Separate BMP-Smad and Olf Signaling Pathways (2000) (452)
- Origins of metastatic traits. (2013) (451)
- SMADs: mediators and regulators of TGF-β signaling (1998) (448)
- VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors. (2011) (426)
- TGF-β Tumor Suppression through a Lethal EMT (2016) (421)
- Crystal Structure of the Cytoplasmic Domain of the Type I TGF β Receptor in Complex with FKBP12 (1999) (419)
- Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells (1987) (413)
- Diverse Cell Surface Protein Ectodomains Are Shed by a System Sensitive to Metalloprotease Inhibitors (*) (1996) (412)
- Transforming growth factor beta regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans. (1988) (402)
- Balancing BMP signaling through integrated inputs into the Smad1 linker. (2007) (396)
- Transforming growth factor-alpha. A model for membrane-anchored growth factors. (1990) (395)
- Lung metastasis genes couple breast tumor size and metastatic spread (2007) (395)
- Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15 (1997) (394)
- Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. (2002) (392)
- Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin (1994) (389)
- Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4 (1997) (380)
- Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells (1994) (380)
- Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination (2000) (379)
- The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development (1993) (377)
- Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites (1994) (377)
- Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway. (1999) (376)
- Determinants of specificity in TGF-beta signal transduction. (1998) (373)
- The TGF beta receptor activation process: an inhibitor- to substrate-binding switch. (2001) (372)
- Therapy-induced tumour secretomes promote resistance and tumour progression (2015) (370)
- The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2. (1997) (366)
- Myc suppression of the p21Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage (2002) (366)
- Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. (1999) (363)
- Physical and Functional Interaction of SMADs and p300/CBP* (1998) (361)
- Selection of Bone Metastasis Seeds by Mesenchymal Signals in the Primary Tumor Stroma (2013) (359)
- p27Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. (1995) (349)
- Hematopoiesis Controlled by Distinct TIF1γ and Smad4 Branches of the TGFβ Pathway (2006) (340)
- Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila (1994) (339)
- Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1 (2003) (337)
- Mechanism of TGFβ receptor inhibition by FKBP12 (1997) (336)
- Is cancer a disease of self-seeding? (2006) (335)
- Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling. (2009) (332)
- Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program. (2001) (330)
- Type beta transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts. (1985) (329)
- Activation of signalling by the activin receptor complex (1996) (326)
- Cellular receptors for type beta transforming growth factor. Ligand binding and affinity labeling in human and rodent cell lines. (1985) (324)
- Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-beta (1989) (324)
- Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling. (2001) (322)
- Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells. (1988) (317)
- Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms. (1990) (315)
- Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity. (2002) (314)
- Ubiquitin-dependent degradation of TGF-β-activated Smad2 (1999) (312)
- Structural basis of Smad2 recognition by the Smad anchor for receptor activation. (2000) (311)
- Transforming growth factor-beta inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor. (1989) (304)
- Distinct altered patterns of p27KIP1 gene expression in benign prostatic hyperplasia and prostatic carcinoma. (1999) (303)
- Differential Interaction of the Cyclin-dependent Kinase (Cdk) Inhibitor p27Kip1 with Cyclin A-Cdk2 and Cyclin D2-Cdk4* (1997) (301)
- ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. (2009) (296)
- Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction. (1990) (294)
- Regulation of cell adhesion receptors by transforming growth factor-beta. Regulation of vitronectin receptor and LFA-1. (1989) (293)
- Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family (1995) (292)
- Direct Binding of Smad1 and Smad4 to Two Distinct Motifs Mediates Bone Morphogenetic Protein-specific Transcriptional Activation ofId1 Gene* (2002) (291)
- Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus. (2002) (290)
- TGF-beta receptors and actions. (1994) (287)
- Surviving at a Distance: Organ-Specific Metastasis. (2015) (284)
- A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis. (1992) (283)
- Analysis of tumor- and stroma-supplied proteolytic networks reveals a brain metastasis-promoting role for cathepsin S (2014) (279)
- Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor (1994) (278)
- Nucleocytoplasmic shuttling of signal transducers (2004) (275)
- Structural determinants of Smad function in TGF-β signaling. (2015) (275)
- Clinical implications of cancer self-seeding (2011) (271)
- Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor alpha to epidermal growth factor receptors promotes cell proliferation. (1990) (269)
- ID genes mediate tumor reinitiation during breast cancer lung metastasis (2007) (264)
- TGFbeta signaling: receptors, transducers, and Mad proteins. (1996) (262)
- Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis (2011) (260)
- The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF‐β receptors (1998) (256)
- A Poised Chromatin Platform for TGF-β Access to Master Regulators (2011) (255)
- Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. (1996) (252)
- C/EBPβ at the core of the TGFβ cytostatic response and its evasion in metastatic breast cancer cells (2006) (244)
- Betaglycan presents ligand to the TGF beta signaling receptor. (1993) (243)
- A rectal cancer organoid platform to study individual responses to chemoradiation (2019) (242)
- A FoxO–Smad synexpression group in human keratinocytes (2006) (241)
- Signaling activity of transforming growth factor beta type II receptors lacking specific domains in the cytoplasmic region (1993) (240)
- Integration of Smad and MAPK pathways: a link and a linker revisited. (2003) (238)
- Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway. (2006) (236)
- Epidermal growth factor-like transforming growth factor. I. Isolation, chemical characterization, and potentiation by other transforming factors from feline sarcoma virus-transformed rat cells. (1983) (235)
- Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation. (2004) (235)
- A Smad action turnover switch operated by WW domain readers of a phosphoserine code. (2011) (234)
- The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution (2020) (234)
- Rapamycin resistance tied to defective regulation of p27Kip1 (1996) (233)
- Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex (1995) (232)
- Smad1 Recognition and Activation by the ALK1 Group of Transforming Growth Factor-β Family Receptors* (1999) (232)
- Loss of receptors for transforming growth factor beta in human T-cell malignancies. (1994) (230)
- Targeting metastatic cancer (2021) (228)
- Myc Downregulation by Transforming Growth Factor β Required for Activation of the p15Ink4b G1 Arrest Pathway (1999) (228)
- Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II. (1991) (224)
- Identification and expression of two forms of the human transforming growth factor‐β‐binding protein endoglin with distinct cytoplasmic regions (1993) (222)
- Serine/threonine kinase receptors: mediators of transforming growth factor beta family signals. (1996) (219)
- MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer. (2011) (219)
- Role of transforming growth factor-β in chondrogenic pattern formation in the embryonic limb: Stimulation of mesenchymal condensation and fibronectin gene expression by exogenenous TGF-β and evidence for endogenous TGF-β-like activity (1991) (219)
- SMADs: mediators and regulators of TGF-beta signaling. (1998) (216)
- Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries. (1980) (213)
- The actions of insulin-like growth factors I and II on cultured Sertoli cells. (1984) (208)
- The transforming growth factor-beta receptor type III is a membrane proteoglycan. Domain structure of the receptor. (1988) (204)
- Regenerative lineages and immune-mediated pruning in lung cancer metastasis (2019) (203)
- Multiple Modes of Repression by the Smad Transcriptional Corepressor TGIF* (1999) (203)
- TGF-β-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition. (2013) (202)
- TGF‐β Receptors and TGF‐β Binding Proteoglycans: Recent Progress in Identifying Their Functional Properties (1990) (201)
- Epigenetic expansion of VHL-HIF signal output drives multi-organ metastasis in renal cancer (2012) (198)
- Human platelet-derived transforming growth factor-beta stimulates parameters of bone growth in fetal rat calvariae. (1986) (195)
- Transforming growth factor-beta switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin. (1989) (194)
- Cleavage of the membrane precursor for transforming growth factor alpha is a regulated process. (1991) (191)
- Nomenclature: Vertebrate Mediators of TGFβ Family Signals (1996) (189)
- Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis (2017) (186)
- The nuclear import function of Smad2 is masked by SARA and unmasked by TGFb-dependent phosphorylation (2000) (182)
- TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1 (2020) (181)
- Cellular distribution of type I and type II receptors for transforming growth factor-beta. (1986) (181)
- Epidermal growth factor signaling via Ras controls the Smad transcriptional co‐repressor TGIF (2001) (175)
- Engagement of bone morphogenetic protein type IB receptor and Smad1 signaling by anti-Müllerian hormone and its type II receptor. (2000) (175)
- Dephosphorylation of the Linker Regions of Smad1 and Smad2/3 by Small C-terminal Domain Phosphatases Has Distinct Outcomes for Bone Morphogenetic Protein and Transforming Growth Factor-β Pathways* (2006) (174)
- The antiproliferative effect of type beta transforming growth factor occurs at a level distal from receptors for growth-activating factors. (1986) (170)
- Glycogen synthase: A new activity ratio assay expressing a high sensitivity to the phosphorylation state (1979) (161)
- Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. (2007) (159)
- TβR-I(6A) Is a Candidate Tumor Susceptibility Allele (1999) (158)
- Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system. (1991) (155)
- Complementation between kinase‐defective and activation‐defective TGF‐beta receptors reveals a novel form of receptor cooperativity essential for signaling. (1996) (154)
- C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells. (2006) (153)
- Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization (2018) (152)
- Smad4/DPC4 Silencing and Hyperactive Ras Jointly Disrupt Transforming Growth Factor-β Antiproliferative Responses in Colon Cancer Cells* (1999) (150)
- Two distinct transmembrane serine/threonine kinases from Drosophila melanogaster form an activin receptor complex (1994) (147)
- E2F and Histone Deacetylase Mediate Transforming Growth Factor β Repression of cdc25A during Keratinocyte Cell Cycle Arrest (1999) (146)
- Binding of two growth factor families to separate domains of the proteoglycan betaglycan. (1992) (144)
- TGF-β singaling and cancer: structural and functional consequences of mutations in Smads (1998) (140)
- p 27 Kip 1 , a cyclin-Cdk inhibitor , links transforming growth factor-13 and contact inhibition to cell cycle arrest (2007) (138)
- TGF‐β control of stem cell differentiation genes (2012) (137)
- Unique players in the BMP pathway: Small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling (2006) (137)
- The Smad transcriptional corepressor TGIF recruits mSin3. (2001) (133)
- Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism (1995) (132)
- Mammalian antiproliferative signals and their targets. (1995) (132)
- Receptors for the TGF-beta family. (1992) (132)
- Distinct Oligomeric States of SMAD Proteins in the Transforming Growth Factor-β Pathway* (2000) (132)
- Platelets and metastasis revisited: a novel fatty link. (2004) (132)
- The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons. (1996) (131)
- Distinct Domain Utilization by Smad3 and Smad4 for Nucleoporin Interaction and Nuclear Import* (2003) (131)
- Heterodimeric transforming growth factor beta. Biological properties and interaction with three types of cell surface receptors. (1988) (125)
- Type beta transforming growth factor from feline sarcoma virus-transformed rat cells. Isolation and biological properties. (1984) (123)
- Sorting out breast-cancer gene signatures. (2007) (123)
- TGF‐β receptors (1992) (122)
- Phase II trial of saracatinib (AZD0530), an oral SRC-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer. (2011) (121)
- Smad 6 inhibits BMP / Smad 1 signaling by specifically competing with the Smad 4 tumor suppressor (1998) (121)
- Controlling TGF- b signaling (2000) (119)
- Multiple signals activate cleavage of the membrane transforming growth factor-alpha precursor. (1991) (118)
- Surviving at a distance: organ specific metastasis. (2015) (118)
- Cleavage of membrane-anchored growth factors involves distinct protease activities regulated through common mechanisms. (1992) (116)
- Genome-wide Impact of the BRG1 SWI/SNF Chromatin Remodeler on the Transforming Growth Factor β Transcriptional Program* (2008) (116)
- Stimulation by insulin-like growth factors is required for cellular transformation by type beta transforming growth factor. (1985) (116)
- Subunit structure of a high-affinity receptor for type beta-transforming growth factor. Evidence for a disulfide-linked glycosylated receptor complex. (1985) (115)
- The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGFα into soluble growth factor (1992) (115)
- Identification of a Drosophila activin receptor. (1993) (114)
- Carboxy-terminally truncated Gli3 proteins associate with Smads (1998) (114)
- The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells. (2017) (114)
- Molecular Pathways: VCAM-1 as a Potential Therapeutic Target in Metastasis (2012) (113)
- The high affinity insulin receptor mediates growth stimulation in rat hepatoma cells. (1982) (113)
- A unique proteolytic cleavage site on the beta subunit of the insulin receptor. (1981) (113)
- Breast cancer banishes p27 from nucleus (2002) (113)
- Characterization of high molecular weight transforming growth factor alpha produced by rat hepatocellular carcinoma cells. (1988) (111)
- Ubiquitin-dependent degradation of TGF-beta-activated smad2. (1999) (111)
- Identifying site-specific metastasis genes and functions. (2005) (110)
- Transforming growth factor beta induces myoblast differentiation in the presence of mitogens. (1992) (110)
- Biologically active precursor for transforming growth factor type alpha, released by retrovirally transformed cells. (1986) (108)
- Early gene responses to transforming growth factor-beta in cells lacking growth-suppressive RB function (1991) (107)
- Role of disulfides in the subunit structure of the insulin receptor. Reduction of class I disulfides does not impair transmembrane signalling. (1982) (107)
- [17] Identification of receptor for type-β transforming growth factor (1987) (106)
- BF-1 Interferes with Transforming Growth Factor β Signaling by Associating with Smad Partners (2000) (105)
- Role of the Juxtamembrane Domains of the Transforming Growth Factor-α Precursor and the β-Amyloid Precursor Protein in Regulated Ectodomain Shedding* (1997) (104)
- Type I transforming growth factor beta receptor maps to 9q22 and exhibits a polymorphism and a rare variant within a polyalanine tract. (1998) (104)
- The transforming growth factors (1985) (104)
- A surface component on GH3 pituitary cells that recognizes transforming growth factor-beta, activin, and inhibin. (1988) (103)
- Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer (2014) (103)
- Identification of a nerve growth factor receptor protein in sympathetic ganglia membranes by affinity labeling. (1981) (102)
- Smad Transcriptional Corepressors in TGFβ Family Signaling (2001) (102)
- Control of junB and extracellular matrix protein expression by transforming growth factor-beta 1 is independent of simian virus 40 T antigen-sensitive growth-sensitive growth-inhibitory events (1991) (101)
- Inhibition of the Transforming Growth Factor β1 Signaling Pathway by the AML1/ETO Leukemia-associated Fusion Protein* (2000) (100)
- Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways. (2012) (98)
- Transforming growth factor-beta (TGF-beta) receptor proteoglycan. Cell surface expression and ligand binding in the absence of glycosaminoglycan chains. (1989) (97)
- Integral membrane glycoprotein properties of the prohormone pro-transforming growth factor-α (1987) (97)
- L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer (2020) (96)
- Extracellular matrix players in metastatic niches (2012) (95)
- Mad Upregulation and Id2 Repression Accompany Transforming Growth Factor (TGF)-β-mediated Epithelial Cell Growth Suppression* (2003) (95)
- The TGF-beta family and its composite receptors. (1994) (95)
- Affinity labeling of multiplication stimulating activity receptors in membranes from rat and human tissues. (1981) (94)
- Insulin action rapidly modulates the apparent affinity of the insulin-like growth factor II receptor. (1983) (94)
- Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients (2021) (91)
- Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2 (2011) (90)
- TGF-β Inhibition and Immunotherapy: Checkmate. (2018) (90)
- Cyclins, Cdks, and cyclin kinase inhibitors. (1994) (90)
- Transforming growth factor-beta modulates the high-affinity receptors for epidermal growth factor and transforming growth factor-alpha (1985) (90)
- Reconstitution and transphosphorylation of TGF‐beta receptor complexes. (1994) (89)
- Signaling Activity of Homologous and Heterologous Transforming Growth Factor-β Receptor Kinase Complexes (*) (1995) (86)
- TGF‐β signaling in development and disease (2012) (86)
- Isoform-specific transforming growth factor-beta binding proteins with membrane attachments sensitive to phosphatidylinositol-specific phospholipase C. (1991) (84)
- TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads. (1998) (83)
- Evidence for the involvement of protein kinase activity in transforming growth factor-beta signal transduction (1992) (82)
- TbetaR-I(6A) is a candidate tumor susceptibility allele. (1999) (82)
- Juxtacrine cell signaling molecules. (1993) (81)
- Cell adhesion to collagen and decreased myogenic gene expression implicated in the control of myogenesis by transforming growth factor beta. (1990) (81)
- Features of a Smad3 MH1-DNA Complex (2003) (79)
- The TGF-beta family of growth and differentiation factors. (1987) (77)
- Internalization of transforming growth factor‐β and its receptor in BALB/c 3T3 fibroblasts (1986) (76)
- Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line. (2001) (76)
- Nomenclature: vertebrate mediators of TGFbeta family signals. (1996) (73)
- A very private TGF-beta receptor embrace. (2008) (73)
- BMP signaling and vertebrate limb development. (1997) (72)
- Modeling metastasis in the mouse. (2010) (70)
- Role of transforming growth factor-beta in chondrogenic pattern formation in the embryonic limb: stimulation of mesenchymal condensation and fibronectin gene expression by exogenenous TGF-beta and evidence for endogenous TGF-beta-like activity. (1991) (70)
- Smad transcriptional corepressors in TGF beta family signaling. (2001) (68)
- Metastasis-Initiating Cells and Ecosystems. (2021) (67)
- RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation (2014) (66)
- Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation (2019) (65)
- Purification of the transforming growth factor-beta (TGF-beta) binding proteoglycan betaglycan. (1991) (63)
- Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors (2017) (63)
- Understanding the molecular mechanisms driving metastasis (2017) (63)
- Diverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analog. (2010) (62)
- Signalling change: signal transduction through the decades (2013) (60)
- Structural properties of a soluble bioactive precursor for transforming growth factor-alpha. (1988) (60)
- Activated release of membrane-anchored TGF-alpha in the absence of cytosol (1993) (59)
- The insulin receptor: structural features (1981) (56)
- Insulin control of rat hepatocyte glycogen synthase and phosphorylase in the absence of glucose (1977) (55)
- TGF-beta receptors and TGF-beta binding proteoglycans: recent progress in identifying their functional properties. (1990) (55)
- Multiple type‐β transforming growth factors and their receptors (1987) (54)
- Generation of transforming growth factor-alpha from the cell surface by an O-glycosylation-independent multistep process. (1990) (53)
- Interaction of Transforming Growth Factor-β Receptor I with Farnesyl-protein Transferase-α in Yeast and Mammalian Cells* (1996) (52)
- Metastatic Competence Can Emerge with Selection of Preexisting Oncogenic Alleles without a Need of New Mutations. (2015) (52)
- Transforming growth factor receptor gene TGFBR2 maps to human chromosome band 3p22. (1994) (50)
- Multimodality imaging of TGFβ signaling in breast cancer metastases (2009) (49)
- Multiple Redox Forms of the Insulin Receptor in Native Liver Membranes (1980) (49)
- Cyclin-dependent kinase inhibitor p57KIP2 in soft tissue sarcomas and Wilms'tumors. (1996) (47)
- Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. (2019) (46)
- Breast cancer tumor size, nodal status, and prognosis: biology trumps anatomy. (2011) (46)
- HER2 silences tumor suppression in breast cancer cells by switching expression of C/EBPß isoforms. (2010) (45)
- Crossing receptor boundaries (1996) (44)
- Cyclin-dependent Kinase Inhibitors Uncouple Cell Cycle Progression from Mitochondrial Apoptotic Functions in DNA-damaged Cancer Cells* (2005) (43)
- Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling (2019) (43)
- Ubiquitin-dependent degradation of (1999) (42)
- Affinity labeling of a transforming growth factor receptor that does not interact with epidermal growth factor. (1982) (41)
- Identification of receptors for type-beta transforming growth factor. (1987) (41)
- Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism (2020) (41)
- Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization (2019) (41)
- ID1 mediates escape from TGF-β tumor suppression in pancreatic cancer. (2019) (40)
- Field Cancerization: Something New Under the Sun (2012) (39)
- Ubiquitin removal in the TGF-β pathway (2012) (36)
- Transforming growth factors. Isolation, characterization, and interaction with cellular receptors. (1985) (36)
- Dexamethasone enhancement of betaglycan (TGF-beta type III receptor) gene expression in osteoblast-like cells. (1994) (35)
- Transforming growth factor-β receptors and binding proteoglycans (1990) (34)
- Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines (2020) (34)
- The type II TGF-beta receptor signals diverse responses in cooperation with the type I receptor. (1992) (34)
- Metastatic Colonization (2016) (33)
- Interrelationships among receptor structures for insulin and peptide growth factors. (1983) (33)
- Subunit structure and dynamics of the insulin receptor. (1982) (33)
- Genomic organization of the human p57KIP2 gene and its analysis in the G401 Wilms' tumor assay. (1996) (32)
- The inactivation of glycogen phosphorylase is not a prerequisite for the activation of liver glycogen synthase (1979) (32)
- Erratum: Transforming growth factor β-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation (Proceedings of the National Academy of Sciences of the United States of America (October 19, 2004) 101, 42 (15231-15236)) (2004) (32)
- Insulin counteraction of α-adrenergic effects on liver glycogen metabolism (1978) (32)
- Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer. (2021) (32)
- Parallel Decreases in the Expression of Receptors for Insulin and Insulin-like Growth Factor I in a Mutant Human Fibroblast Line (1983) (31)
- Tissue factor-specific ultra-bright SERRS nanostars for Raman detection of pulmonary micrometastases. (2017) (29)
- Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway (2005) (25)
- Negative regulators of growth. (1992) (25)
- Mechanisms in TGF-beta action. (1991) (24)
- Different Sensitivity of the Transforming Growth Factor-β Cell Cycle Arrest Pathway to c-Myc and MDM-2* (2000) (24)
- A helping hand from proteoglycans (1991) (24)
- Role of the juxtamembrane domains of the transforming growth factor-alpha precursor and the beta-amyloid precursor protein in regulated ectodomain shedding. (1997) (24)
- Affinity labeling of a nerve growth factor receptor component on rat pheochromocytoma (PC12) cells. (1982) (22)
- MITI minimum information guidelines for highly multiplexed tissue images (2021) (22)
- Opposite Smad and Chicken Ovalbumin Upstream Promoter Transcription Factor Inputs in the Regulation of the Collagen VII Gene Promoter by Transforming Growth Factor-β* (2004) (21)
- Transforming growth factor-α (1991) (21)
- Intracerebral infusion of the bispecific targeted toxin DTATEGF in a mouse xenograft model of a human metastatic non-small cell lung cancer (2012) (17)
- Transforming growth factor-beta receptors and binding proteoglycans. (1990) (16)
- Wounding Smad (1999) (15)
- Multiple type-beta transforming growth factors and their receptors. (1987) (15)
- Arresting supporters: targeting neutrophils in metastasis (2016) (13)
- Publisher Correction: Contextual determinants of TGFβ action in development, immunity and cancer (2018) (12)
- Multiple phosphorylation of rabbit muscle glycogen synthase by glycogen synthase kinase‐1 (1979) (11)
- New concepts in tissue-specific metastases. (2003) (11)
- Supplemental Data Balancing BMP Signaling through Integrated Inputs into the Smad 1 Linker (2007) (10)
- [14] Affinity cross-linking of receptors for insulin and the insulin-like growth factors I and II (1985) (10)
- Modulation of type α transforming growth factor receptors by a phorbol ester tumor promoter (1985) (9)
- Identification of receptor proteins for type-alpha transforming growth factor. (1987) (9)
- Corrigendum: Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer (2017) (9)
- H3K18ac Primes Mesendodermal Differentiation upon Nodal Signaling (2019) (8)
- XTrR-I is a TGFβ receptor and overexpression of a truncated form of the receptor inhibits axis formation and dorsalising activity (1998) (8)
- Hypoxia signaling--license to metastasize. (2013) (8)
- Targeting S100A9–ALDH1A1–Retinoic Acid Signaling to Suppress Brain Relapse in EGFR-Mutant Lung Cancer (2022) (8)
- Author Correction: Guidelines and definitions for research on epithelial–mesenchymal transition (2021) (7)
- Erratum: Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway (Proceedings of the National Academy of Sciences of the United States of America) (September 27, 2005) 102 (13909-13914) DOI: 10.1073/pnas.0506517102)) (2006) (6)
- Type , 8 Transforming Growth Factor from Feline Sarcoma Virus-transformed Rat Cells (2001) (6)
- [Receptors and functions of TGF-beta, a crucial cytokine in wound healing]. (2003) (6)
- Responsiveness to Transforming Growth Factor-@ (TGF-@) Restored by Genetic Complementation between Cells Defective in TGF-P Receptors I and 11” (2001) (6)
- Networks of tumor suppressors (2000) (6)
- TGF-β in developmental and fibrogenic EMTs (2022) (6)
- Transforming Growth Factor-@ Stimulates the Expression of Fibronectin and Collagen and Their Incorporation i to the Extracellular Matrix (2001) (6)
- [10] Purification of type-α transforming growth factor from transformed cells (1987) (5)
- Anti-tumor effects of an ID antagonist with no observed acquired resistance (2021) (5)
- The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos (2021) (5)
- Synthesis of glycogen from fructose in the presence of elevated levels of glycogen phosphorylase a in rat hepatocytes (1980) (5)
- 11 Growth Control by TGF-β: Mechanisms Controlling Cell Cycle Progression and Apoptosis (2008) (5)
- The subcellular locations of plŜ **̂ "̂ ^ and p27Kipi coordinate their inhibitory interactions with cdk4 and cdk2 (2007) (5)
- Mechanisms in TGF‐β Action (2007) (5)
- CHAPTER 4 – Mechanisms of Biological Signaling by the Insulin Receptor (1984) (4)
- Cell regulation. (2008) (4)
- 18 – Invasion and Metastasis (2015) (4)
- Anti-tumor effects of an Id antagonist with no acquired resistance (2020) (4)
- Mechanism of TGFβ receptor inhibition by FKBP12 case of the activin-binding protein follistatin (Nakamura (2013) (4)
- Growth Stimulation by Cell to Cell Contact and Growth Suppression: Two Aspects of the Biology of Transforming Growth Factors (1990) (3)
- Development of a Mouse Model of Leptomeningeal Metastasis (P7.014) (2014) (3)
- A rectal cancer model establishes a platform to study individual responses to chemoradiation (2019) (3)
- Mechanism for Tumor Progression in Lymphomatoid Papulosis: Hypothesis Based on Studies of Tumor Cell Lines Clonally Derived from Lymphomatoid Papulosis (1994) (3)
- STRUCTURAL FEATURES OF THE INSULIN EFFECTOR SYSTEM: RELATION TO HEXOSE TRANSPORT ACTIVATION (1980) (3)
- Advances in Brief T b RI ( 6 A ) Is a Candidate Tumor Susceptibility Allele 1 (1999) (3)
- Transforming Grown Factor-β Signaling in Immunity and Cancer (2020) (3)
- Author response: Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization (2019) (2)
- Erratum to: Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization (Nature Cell Biology, (2018), 20, 8, (966-978), 10.1038/s41556-018-0138-8) (2019) (2)
- Phase I trial of the TNF-α inhibitor certolizumab plus chemotherapy in stage IV lung adenocarcinomas (2022) (2)
- Author Correction: L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer (2020) (2)
- Purification of type-alpha transforming growth factor from transformed cells. (1987) (2)
- BM-06MECHANISTIC INVESTIGATIONS OF LEPTOMENINGEAL METASTASIS FROM SOLID TUMORS. (2014) (2)
- Direct modulation of insulin-like growth factor-II receptor affinity by insulin action in adipocytes and H-35 hepatoma cells (1982) (2)
- Cytotoxic lymphocytes use mechanosurveillance to target biophysical vulnerabilities in cancer (2020) (2)
- Abstract #5667: ADAMTS1 and MMP1 promote breast cancer bone metastasis through a bone stromal cell-mediated osteolytic signaling cascade (2009) (2)
- Transforming Growth Factor-/3 Modulates the High-affinity Receptors for Epidermal Growth Factor and Transforming Growth Factor-c (2002) (2)
- Modulation of type alpha transforming growth factor receptors by a phorbol ester tumor promoter. (1985) (2)
- Guidelines and definitions for research on epithelial–mesenchymal transition (2020) (1)
- Labeling and Isolation of Fluorouracil Tagged RNA by Cytosine Deaminase Expression. (2019) (1)
- Cell multiplication. (1997) (1)
- Publisher Correction: TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1 (2020) (1)
- STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma (2023) (1)
- Abstract SY19-01: TGFβ and immune evasion in metastatic cancer (2021) (1)
- Receptors for nerve growth factor in responsive peripheral neurons. (1983) (1)
- NEDD4L WW2 domain in complex with a Smad7 derived peptide (2012) (0)
- Abstract 5763: VCAM1 mediates aggressive bone metastasis outbreak from tumor dormancy by engaging α4β1-positive osteoclast progenitor cells (2010) (0)
- 52. BrMPANEL: A PUBLIC RESOURCE OF ORGANOTROPIC CELL LINES (2020) (0)
- Abstract 2844: Systems biology analysis of tumor and stromal genes in different metastatic microenvironments (2011) (0)
- Abstract LT016: Mechanosurveillance eliminates disseminated cancer cells by sensing their mechanical compliance (2021) (0)
- BMET-03SOLID TUMORS EXPLOIT INNATE IMMUNITY TO GENERATE LEPTOMENINGEAL METASTASES (2015) (0)
- Structure of the second domain of human Nedd4L in complex with a phosphorylated pTPY motif derived from human Smad3 (2011) (0)
- Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization (2018) (0)
- IN THE SPOTLIGHT Hypoxia Signaling—License to Metastasize (2013) (0)
- Receptor of the third kind (1993) (0)
- Making indigenous arbuscular mycorrhizal fungi beneficial for crop plants - Can soil mixing help? (2016) (0)
- 1: Chemokine networks regulate the balance of pro-and anti-tumor granulocytes that determine metastatic progression in breast cancer models (2013) (0)
- TIF1γ Knockdown Enhances Hematopoietic Stem Cell Self Renewal with Preferential Myeloid Differentiation and Delayed Erythropoiesis (2011) (0)
- Abstract IA25: Metastasis pathways (2013) (0)
- Author response: The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos (2021) (0)
- Publisher Correction: Contextual determinants of TGFβ action in development, immunity and cancer (2018) (0)
- Author Correction: Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization (2018) (0)
- Smurf1 WW2 domain in complex with a Smad7 derived peptide (2012) (0)
- Abstract IA-19: Deconstructing metastasis (2009) (0)
- Author response: Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer (2014) (0)
- Kathryn Anderson, grand dame of developmental biology (2021) (0)
- Dissecting and Targeting Latent Metastasis (2014) (0)
- A phase I trial of certolizumab plus chemotherapy in patients with stage IV lung adenocarcinomas. (2016) (0)
- TMOD-36. PRECISE INVESTIGATION OF CANCER STEM CELLS IN A MOUSE GLIOBLASTOMA MODEL (2018) (0)
- Alteration in number and affinity of insulin receptors on insulin-resistant cloudman melanoma cells. Abstr. (1983) (0)
- Abstract IA006: Metastasis initiating cells and ecosystems (2021) (0)
- Abstract 2825: Mechanosurveillance by immunity targets mechanical compliance of metastatic cells (2021) (0)
- Crystal structure of Smad3-MH1 bound to DNA at 2.4 A resolution (2004) (0)
- Table of Contents (1995) (0)
- Abstract IA18: Latency and immune evasion of metastatic stem cells (2016) (0)
- Cellular Distribution of Type I and Type I1 Receptors for Transforming Growth Factor$* Affinity labeling of target cells (2001) (0)
- Abstract A01: Investigating clonal heterogeneity and transcriptional vulnerabilities in latent metastasis (2016) (0)
- Abstract PL03-02: Microenvironment survival signals for disseminated cancer cells (2011) (0)
- The transcription factor Rreb1 regulates epithelial architecture and invasiveness in gastrulating mouse embryos (2020) (0)
- TMIC-02. TARGETING CARCINOMA–ASTROCYTE GAP JUNCTIONS IN BRAIN METASTASIS (2016) (0)
- Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1 (2022) (0)
- complex.tion within the receptor signaling by a mutation that prevents Disruption of transforming growth factor beta (2013) (0)
- 2 Micrometastasis Niches, Signals and Pathways (2012) (0)
- Structure of the second WW domain from human YAP in complex with a human Smad1 derived peptide (2011) (0)
- CRYSTAL STRUCTURE OF THE SMAD4 TUMOR SUPPRESSOR C-TERMINAL DOMAIN (1998) (0)
- Abstract A12: L1CAM defines the regenerative origin of metastasis initiating cells in colorectal cancer (2020) (0)
- Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors (2017) (0)
- Chapter 3. Osteoclast Biology and Bone Resorption (2008) (0)
- Abstract PR004: Mechanistic basis for TGF-β-induced fibrogenic EMTs in metastasis (2023) (0)
- Cell cycle control by TGF-β signals (1999) (0)
- Physiopathologic Role of TGF-b in Nephropathies of Diverse Etiologies. (2003) (0)
- Signaling Activity of Transforming Growth Factor 3 Receptors Lacking Specific Domains in the Cytoplasmic Region Type II (0)
- Structure of first WW domain of human YAP in complex with a human Smad1 doubly-phosphorilated derived peptide. (2011) (0)
- Abstract C8: Bone metastasis seed preselection by the primary tumor stroma (2013) (0)
- YAP WW1 in complex with a Smad7 derived peptide (2012) (0)
- MEMBRANE-ANCHORE D GROWTH FACTORS (1993) (0)
- Distinct tumor architectures for metastatic colonization of the brain (2023) (0)
- Transforming growth factor-alpha. (1991) (0)
- OpposingBMPandEGF signallingpathways convergeon theTGF-b familymediatorSmad 1 (1997) (0)
- IN1 ABC2 AWARD ABSTRACT: ORIGINS OF METASTATIC TRAITS (2013) (0)
- Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation (2019) (0)
- Transforming Growth Factor β and Growth Suppression1 (1992) (0)
- Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide (2011) (0)
- Anti-tumor effects of an ID antagonist with no observed acquired resistance (2021) (0)
- Abstract IA13: Niches and pathways of latent and overt metastasis (2013) (0)
- SMAD phosphorylation and the TGF-beta pathway (2010) (0)
- Abstract 3015: Precise investigation of cancer stem cells in mouse glioblastoma (2018) (0)
- Author Correction: Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization (2018) (0)
- Structure of the first WW domain of human Smurf1 in complex with a mono-phosphorylated human Smad1 derived peptide (2011) (0)
- collagen and mechanical forces Biomechanics of the lung parenchyma: critical roles of (2005) (0)
- YAP WW2 in complex with a Smad7 derived peptide (2012) (0)
- Contextual determinants of TGFβ action in development, immunity and cancer (2018) (0)
- Abstract B40: Paracrine interactions through CXCL1/2 chemokines promote breast cancer metastasis and chemoresistance (2012) (0)
- Smurf2 WW3 domain in complex with a Smad7 derived peptide (2012) (0)
- The TGFβ pathway in basic oncology (2005) (0)
- Abstract IA18: A brain metastasis-promoting role for cathepsin S identified from analysis of tumor- and stroma-supplied proteolytic networks (2015) (0)
- TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1 (2020) (0)
- Abstract SY20-03: Metastatic latency and immune evasion by cancer stem cells (2016) (0)
- Third WW domain of human Nedd4L in complex with doubly phosphorylated human smad3 derived peptide (2011) (0)
- CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12 (2001) (0)
- Insulin counteraction of alpha-adrenergic effects on liver glycogen metabolism. (1978) (0)
- Abstract 209: Metastatic colonization in the perivascular niche: A mechanotransduction perspective (2019) (0)
- Abstract A29: Cooption of the reactive stroma by brain metastasis relies on protease inhibitors (2013) (0)
- Abstract 5713: Reprogramming of serine metabolism during breast cancer progression (2020) (0)
- Targeting metastatic cancer (2021) (0)
- Abstract 4990: Regenerative origin of colorectal metastasis stem cells (2018) (0)
- Abstract A30: AKT activation as a mechanism of escape from TGFβ-mediated lethal EMT (2016) (0)
- Publisher Correction: TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1 (2020) (0)
- Congratulations for ten years of science (2015) (0)
- Abstract PR06: Metastatic latency and immune evasion mediated by autocrine WNT inhibition (2016) (0)
- Structure of the first domain of human PIN1 in complex with a human Smad3 derived peptide. (2011) (0)
- Regenerative lineages and immune-mediated pruning in lung cancer metastasis (2020) (0)
- Immunostaining Protocol: P-Stat3 (Xenograft and Mice). (2014) (0)
- Structure of the second domain of human Smurf1 in complex with a human Smad1 derived peptide (2011) (0)
- Affinity Labelling Techniques for Low-Abundance Membrane Components: Peptide Hormone Receptors and the D-Glucose Transporter (1984) (0)
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