JoAnne Flynn
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American microbiologist and immunologist
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JoAnne Flynnbiology Degrees
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Immunology
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Microbiology
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Biology
JoAnne Flynn's Degrees
- PhD Microbiology Stanford University
- Doctorate Immunology Stanford University
Why Is JoAnne Flynn Influential?
(Suggest an Edit or Addition)According to Wikipedia, JoAnne L. Flynn is an American microbiologist and immunologist. She is a distinguished professor at the University of Pittsburgh School of Medicine where she researches mycobacterium tuberculosis pathogenesis and immunology. She was president of the American Association of Immunologists.
JoAnne Flynn's Published Works
Published Works
- An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection (1993) (2541)
- SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues (2020) (1833)
- Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice. (1995) (1779)
- The spectrum of latent tuberculosis: rethinking the biology and intervention strategies (2009) (1276)
- Immunology of tuberculosis. (2003) (1191)
- Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. (1992) (848)
- IL-17 Production Is Dominated by γδ T Cells rather than CD4 T Cells during Mycobacterium tuberculosis Infection1 (2006) (730)
- Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates (2008) (584)
- Effects of Tumor Necrosis Factor Alpha on Host Immune Response in Chronic Persistent Tuberculosis: Possible Role for Limiting Pathology (2001) (567)
- Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis. (1999) (552)
- Tuberculosis: What We Don’t Know Can, and Does, Hurt Us (2010) (503)
- Tuberculosis: Latency and Reactivation (2001) (485)
- Activation of human dendritic cells following infection with Mycobacterium tuberculosis. (1997) (477)
- Experimental Mycobacterium tuberculosis Infection of Cynomolgus Macaques Closely Resembles the Various Manifestations of Human M. tuberculosis Infection (2003) (453)
- Understanding Latent Tuberculosis: A Moving Target (2010) (446)
- IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. (2006) (440)
- Latent tuberculosis: mechanisms of host and bacillus that contribute to persistent infection. (2003) (420)
- Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension (2006) (390)
- Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection (2011) (386)
- Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model (2009) (384)
- Depletion of Cd4+ T Cells Causes Reactivation of Murine Persistent Tuberculosis despite Continued Expression of Interferon γ and Nitric Oxide Synthase 2 (2000) (377)
- IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection. (1995) (369)
- Macrophages and control of granulomatous inflammation in tuberculosis (2011) (350)
- Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis (2001) (346)
- Immunology of tuberculosis and implications in vaccine development. (2004) (336)
- Heterogeneity in tuberculosis (2017) (315)
- Immune evasion by Mycobacterium tuberculosis: living with the enemy. (2003) (296)
- Lessons from experimental Mycobacterium tuberculosis infections. (2006) (294)
- Prevention of tuberculosis in macaques after intravenous BCG immunization (2020) (279)
- Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms (2013) (278)
- HIV-1/Mycobacterium tuberculosis Coinfection Immunology: How Does HIV-1 Exacerbate Tuberculosis? (2011) (277)
- Tumor necrosis factor and chemokine interactions in the formation and maintenance of granulomas in tuberculosis. (2005) (273)
- Sterilization of granulomas is common in both active and latent tuberculosis despite extensive within-host variability in bacterial killing (2013) (271)
- Fate of Mycobacterium tuberculosis within Murine Dendritic Cells (2001) (249)
- Early Events in Mycobacterium tuberculosis Infection in Cynomolgus Macaques (2006) (245)
- Reactivation of Latent Tuberculosis: Variations on the Cornell Murine Model (1999) (244)
- Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization (2015) (243)
- Effects of aminoguanidine on latent murine tuberculosis. (1998) (241)
- IFN-γ from CD4 T Cells Is Essential for Host Survival and Enhances CD8 T Cell Function during Mycobacterium tuberculosis Infection (2013) (235)
- Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model. (2010) (220)
- Early Emergence of CD8+ T Cells Primed for Production of Type 1 Cytokines in the Lungs of Mycobacterium tuberculosis-Infected Mice (1999) (212)
- The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection. (2012) (209)
- Antimicrobial activity of MHC class I-restricted CD8+ T cells in human tuberculosis. (2000) (207)
- The protective immune response to Mycobacterium tuberculosis. (1995) (192)
- The immunological aspects of latency in tuberculosis. (2004) (188)
- Adjuvanting a subunit COVID-19 vaccine to induce protective immunity (2021) (188)
- Latent tuberculosis: what the host “sees”? (2011) (179)
- CD8+ CTL from Lungs of Mycobacterium tuberculosis-Infected Mice Express Perforin In Vivo and Lyse Infected Macrophages1 (2000) (178)
- CD4+ T Cells Are Required for the Development of Cytotoxic CD8+ T Cells During Mycobacterium tuberculosis Infection1 (2001) (171)
- The Inducible Nitric Oxide Synthase Locus Confers Protection against Aerogenic Challenge of Both Clinical and Laboratory Strains of Mycobacterium tuberculosis in Mice (2001) (169)
- Mycobacterium tuberculosis in Chemokine Receptor 2-Deficient Mice: Influence of Dose on Disease Progression (2002) (169)
- TNF Influences Chemokine Expression of Macrophages In Vitro and That of CD11b+ Cells In Vivo during Mycobacterium tuberculosis Infection1 (2004) (163)
- The role of B cells and humoral immunity in Mycobacterium tuberculosis infection. (2014) (162)
- Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load (2010) (160)
- Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens (2013) (159)
- Tumor Necrosis Factor Blockade in Chronic Murine Tuberculosis Enhances Granulomatous Inflammation and Disorganizes Granulomas in the Lungs (2008) (157)
- What's good for the host is good for the bug. (2005) (155)
- Tumor necrosis factor and tuberculosis. (2007) (152)
- Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography (2016) (152)
- Synergy between Individual TNF-Dependent Functions Determines Granuloma Performance for Controlling Mycobacterium tuberculosis Infection1 (2009) (152)
- Infection with Helicobacter pylori Is Associated with Protection against Tuberculosis (2010) (147)
- CD8+ T cells in tuberculosis. (2002) (145)
- CD8 T cells and Mycobacterium tuberculosis infection (2015) (143)
- CCR5-Deficient Mice Control Mycobacterium tuberculosis Infection despite Increased Pulmonary Lymphocytic Infiltration1 (2004) (141)
- CD40, but not CD40L, is required for the optimal priming of T cells and control of aerosol M. tuberculosis infection. (2003) (140)
- Chemokines and tuberculosis. (2003) (139)
- Dendritic Cell Trafficking and Antigen Presentation in the Human Immune Response to Mycobacterium tuberculosis 1 (2004) (139)
- CD8+ T Cells Participate in the Memory Immune Response to Mycobacterium tuberculosis (2001) (139)
- Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis (2017) (138)
- Non-human primates: a model for tuberculosis research. (2003) (136)
- Macrophage Polarization Drives Granuloma Outcome during Mycobacterium tuberculosis Infection (2014) (136)
- Immunology studies in non‐human primate models of tuberculosis (2015) (132)
- Neutralization of tumor necrosis factor (TNF) by antibody but not TNF receptor fusion molecule exacerbates chronic murine tuberculosis. (2007) (129)
- Immune responses in tuberculosis. (2000) (129)
- Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques (2012) (114)
- Activated B cells in the granulomas of nonhuman primates infected with Mycobacterium tuberculosis. (2012) (114)
- PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis (2014) (110)
- Modeling tuberculosis in nonhuman primates. (2014) (110)
- CD4 T cell depletion exacerbates acute Mycobacterium tuberculosis while reactivation of latent infection is dependent on severity of tissue depletion in cynomolgus macaques. (2012) (109)
- Vaccination with the T Cell Antigen Mtb 8.4 Protects Against Challenge with Mycobacterium tuberculosis1 (2001) (105)
- SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts (2020) (102)
- Differential Virulence and Disease Progression following Mycobacterium tuberculosis Complex Infection of the Common Marmoset (Callithrix jacchus) (2013) (99)
- CD4(+) regulatory T cells in a cynomolgus macaque model of Mycobacterium tuberculosis infection. (2010) (96)
- Differences in Reactivation of Tuberculosis Induced from Anti-TNF Treatments Are Based on Bioavailability in Granulomatous Tissue (2007) (96)
- B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response (2013) (95)
- CD4 T Cells Are Required for the Development of Cytotoxic CD8 T Cells During Mycobacterium tuberculosis Infection (2001) (93)
- The Importance of First Impressions: Early Events in Mycobacterium tuberculosis Infection Influence Outcome (2016) (92)
- TNF and IL-10 are major factors in modulation of the phagocytic cell environment in lung and lymph node in tuberculosis: a next-generation two-compartmental model. (2010) (90)
- Differential Risk of Tuberculosis Reactivation among Anti-TNF Therapies Is Due to Drug Binding Kinetics and Permeability (2012) (89)
- Infection Dynamics and Response to Chemotherapy in a Rabbit Model of Tuberculosis using [18F]2-Fluoro-Deoxy-d-Glucose Positron Emission Tomography and Computed Tomography (2012) (87)
- Profiling Antibodies to Mycobacterium tuberculosis by Multiplex Microbead Suspension Arrays for Serodiagnosis of Tuberculosis (2007) (87)
- PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis (2016) (86)
- Contribution of CD8+ T cells to control of Mycobacterium tuberculosis infection. (2006) (85)
- Contribution of CD8+ T Cells to Control of Mycobacterium tuberculosis Infection1 (2006) (85)
- The End of the Binary Era: Revisiting the Spectrum of Tuberculosis (2018) (81)
- Long-Term Control of Mycobacterium tuberculosis Infection Is Mediated by Dynamic Immune Responses1 (2005) (80)
- Rhesus Macaques Are More Susceptible to Progressive Tuberculosis than Cynomolgus Macaques: a Quantitative Comparison (2017) (79)
- Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques (2016) (77)
- Induction of M3-Restricted Cytotoxic T Lymphocyte Responses by N-Formylated Peptides Derived from Mycobacterium tuberculosis (2001) (75)
- Abatacept treatment does not exacerbate chronic Mycobacterium tuberculosis infection in mice. (2007) (73)
- Simian Immunodeficiency Virus-Induced Changes in T Cell Cytokine Responses in Cynomolgus Macaques with Latent Mycobacterium tuberculosis Infection Are Associated with Timing of Reactivation (2011) (72)
- Experimental Pneumocystis carinii pneumonia in simian immunodeficiency virus-infected rhesus macaques. (2003) (63)
- Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates. (2017) (63)
- In Situ Studyof Abundant Expression of Proinflammatory Chemokines and Cytokines inPulmonary Granulomas That Develop in Cynomolgus MacaquesExperimentally Infected with Mycobacteriumtuberculosis (2003) (62)
- The role of B cells and humoral immunity in Mycobacterium tuberculosis infection. (2013) (61)
- New approaches to tuberculosis surveillance in nonhuman primates. (2008) (61)
- Long-Term Control of Mycobacterium tuberculosis Infection Is Mediated by Dynamic Immune Responses (2005) (61)
- Computational Modeling Predicts IL-10 Control of Lesion Sterilization by Balancing Early Host Immunity–Mediated Antimicrobial Responses with Caseation during Mycobacterium tuberculosis Infection (2015) (61)
- A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment. (2015) (60)
- A comparison of random vs. chemotaxis-driven contacts of T cells with dendritic cells during repertoire scanning. (2008) (59)
- Recombinant bacille Calmette-Guérin priming against measles. (1995) (58)
- The Chemokine Receptor CXCR3 Attenuates the Control of Chronic Mycobacterium tuberculosis Infection in BALB/c Mice1 (2007) (57)
- Proteome-scale antibody responses and outcome of Mycobacterium tuberculosis infection in nonhuman primates and in tuberculosis patients. (2012) (57)
- Cytotoxicity and Secretion of Gamma Interferon Are Carried Out by Distinct CD8 T Cells during Mycobacterium tuberculosis Infection (2009) (57)
- Predicting lymph node output efficiency using systems biology. (2013) (54)
- Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques (2018) (54)
- Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques (2018) (54)
- A Novel Sample Processing Method for Rapid Detection of Tuberculosis in the Stool of Pediatric Patients Using the Xpert MTB/RIF Assay (2016) (53)
- Granzyme B‐expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis‐infected cynomolgus macaques (2015) (51)
- A Sterilizing Tuberculosis Treatment Regimen Is Associated with Faster Clearance of Bacteria in Cavitary Lesions in Marmosets (2015) (48)
- Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques (2017) (43)
- Induction of Mycobacterium tuberculosis-Specific Primary and Secondary T-Cell Responses in Interleukin-15-Deficient Mice (2005) (42)
- Tuberculosis: global approaches to a global disease. (2010) (42)
- The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans. (2015) (39)
- Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1–Expressing Immune Cells (2017) (39)
- Interleukin-12 Therapy Reduces the Number of Immune Cells and Pathology in Lungs of Mice Infected with Mycobacterium tuberculosis (2004) (39)
- Active transforming growth factor-β is associated with phenotypic changes in granulomas after drug treatment in pulmonary tuberculosis (2016) (38)
- Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control (2022) (37)
- Detection and treatment of subclinical tuberculosis. (2012) (36)
- Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques (2019) (35)
- Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes (2017) (35)
- Alterations in T lymphocyte profiles of bronchoalveolar lavage fluid from SIV- and Pneumocystis carinii-coinfected rhesus macaques. (2002) (34)
- Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome (2016) (34)
- Major histocompatibility complex class I-restricted T cells are necessary for protection against M. tuberculosis in mice. (1993) (34)
- Early Whole Blood Transcriptional Signatures Are Associated with Severity of Lung Inflammation in Cynomolgus Macaques with Mycobacterium tuberculosis Infection (2016) (32)
- Identifying mechanisms driving formation of granuloma-associated fibrosis during Mycobacterium tuberculosis infection. (2017) (32)
- IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Mycobacterium tuberculosis Infection (2019) (30)
- Robust IgM responses following intravenous vaccination with Bacille Calmette–Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques (2021) (30)
- The Purinergic P2X7 Receptor Is Not Required for Control of Pulmonary Mycobacterium tuberculosis Infection (2005) (30)
- Low Levels of T Cell Exhaustion in Tuberculous Lung Granulomas (2018) (29)
- Pulmonary Tuberculosis in Monkeys (2010) (29)
- Effect of mycobacterial infection on virus loads and disease progression in simian immunodeficiency virus-infected rhesus monkeys. (2000) (28)
- Role of Tl and T2 Cytokines in the Response to Mycobacterium tuberculosis (1996) (28)
- Lymph nodes—The neglected battlefield in tuberculosis (2020) (27)
- Comparison of the effects of pathogenic simian human immunodeficiency virus strains SHIV-89.6P and SHIV-KU2 in cynomolgus macaques. (2008) (27)
- A new method to evaluate macaque health using exhaled breath: A case study of M. tuberculosis in a BSL-3 setting. (2017) (26)
- SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis (2020) (26)
- Identification of Mycobacterium tuberculosis using volatile biomarkers in culture and exhaled breath (2018) (25)
- Large Scale Comparison of Innate Responses to Viral and Bacterial Pathogens in Mouse and Macaque (2011) (25)
- New insights into mathematical modeling of the immune system (2006) (25)
- The spectrum of latent tuberculosis: rethinking the goals of prophylaxis (2014) (23)
- CD 4 Regulatory T cells in a Cynomolgus Macaque Model of Mycobacterium tuberculosis Infection 1 , 2 , 3 (2011) (22)
- The mutation rate of mycobacterial repetitive unit loci in strains of M. tuberculosis from cynomolgus macaque infection (2013) (22)
- Afferent and efferent interfaces of lymph nodes are distinguished by expression of lymphatic endothelial markers and chemokines. (2007) (22)
- Inoculation Dose of Mycobacterium tuberculosis Does Not Influence Priming of T Cell Responses in Lymph Nodes (2013) (21)
- Aberrant TGF‐β signaling reduces T regulatory cells in ICAM‐1‐deficient mice, increasing the inflammatory response to Mycobacterium tuberculosis (2009) (20)
- Evaluation of IL-1 Blockade as an Adjunct to Linezolid Therapy for Tuberculosis in Mice and Macaques (2020) (20)
- Monocyte-Derived IL-5 Reduces TNF Production by Mycobacterium tuberculosis–specific CD4 T Cells during SIV/M. tuberculosis Coinfection (2013) (19)
- Mutual attraction: Does it benefit the host or the bug? (2004) (19)
- Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates (2021) (18)
- Animal Models of Tuberculosis (2005) (18)
- Plasma antibody profiles in non‐human primate tuberculosis (2014) (18)
- Diversity of Human and Macaque Airway Immune Cells at Baseline and during Tuberculosis Infection. (2016) (16)
- Profiling the airway in the macaque model of tuberculosis reveals variable microbial dysbiosis and alteration of community structure (2018) (16)
- A Systems Biology Approach for Understanding Granuloma Formation and Function in Tuberculosis (2013) (15)
- A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination (2019) (14)
- Spatial Organization and Recruitment of Non-Specific T Cells May Limit T Cell-Macrophage Interactions Within Mycobacterium tuberculosis Granulomas (2021) (14)
- Measurement of leukocyte trafficking kinetics in macaques by serial intravascular staining (2021) (13)
- Very Low Doses of Mycobacterium tuberculosis Yield Diverse Host Outcomes in Common Marmosets (Callithrix jacchus). (2016) (12)
- Spectrum of latent tuberculosis — existing tests cannot resolve the underlying phenotypes: author's reply (2010) (12)
- Why is IFN-γ insufficient to control tuberculosis? (1999) (12)
- Experimental Animal Models of Tuberculosis (2017) (12)
- Noninvasive Test for Tuberculosis Detection among Primates (2015) (12)
- Multimodal profiling of lung granulomas reveals cellular correlates of tuberculosis control (2021) (11)
- Prospective Discrimination of Controllers From Progressors Early After Low-Dose Mycobacterium tuberculosis Infection of Cynomolgus Macaques using Blood RNA Signatures (2018) (10)
- Why is IFN-gamma insufficient to control tuberculosis? (1999) (10)
- Modeling pathogen and host: in vitro, in vivo and in silico models of latent Mycobacterium tuberculosis infection (2005) (10)
- Recombinant BCG as an antigen delivery system. (1994) (10)
- Single-cell profiling of tuberculosis lung granulomas reveals functional lymphocyte signatures of bacterial control (2020) (9)
- In vivo imaging in an ABSL-3 regional biocontainment laboratory. (2014) (9)
- Integrating Non-human Primate, Human, and Mathematical Studies to Determine the Influence of BCG Timing on H56 Vaccine Outcomes (2018) (8)
- Tuberculosis Research using Nonhuman Primates (2012) (7)
- Mycobacterial infections and the inflammatory seesaw. (2010) (7)
- Measuring T-cell function in animal models of tuberculosis by ELISPOT. (2005) (7)
- Challenges and future in vaccines, drug development, and immunomodulatory therapy. (2014) (7)
- T cell transcription factor expression evolves over time in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques (2022) (6)
- Overcoming math anxiety: Malthus meets Koch (2005) (6)
- Developing vaccines to prevent sustained infection with Mycobacterium tuberculosis: Conference proceedings: National Institute of Allergy and Infectious Diseases, Rockville, Maryland USA, November 7, 2014. (2015) (5)
- Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates (2021) (5)
- Retention of 64Cu-FLFLF, a Formyl Peptide Receptor 1-Specific PET Probe, Correlates with Macrophage and Neutrophil Abundance in Lung Granulomas from Cynomolgus Macaques. (2021) (5)
- Strategies for Achieving Gender Equity and Work–Life Integration in Physician–Scientist Training (2021) (5)
- Immune cell interactions in tuberculosis (2022) (5)
- Pharmacokinetics of tedizolid, sutezolid, and sutezolid-M1 in non-human primates. (2020) (5)
- The role of IL-10 during early M. tuberculosis infection in a non-human primate model (2017) (4)
- Developing tuberculosis vaccines for people with HIV: consensus statements from an international expert panel. (2022) (3)
- Spatial and temporal evolution of lung granulomas in a cynomolgus macaque model of Mycobacterium tuberculosis infection. (2018) (3)
- ABATACEPT TREATMENT DOES NOT IMPAIR HOST RESISTANCE TO CHRONIC MYCOBACTERIUM TUBERCULOSIS INFECTION IN MICE: 148 (2006) (3)
- Title: SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and prolonged shedding of infectious virus from both respiratory and gastrointestinal tracts (2020) (3)
- Vaccination route has an impact on level of protection of non-human primates from tuberculosis (2016) (3)
- Evaluation of IL-1 blockade as a host-directed therapy for tuberculosis in mice and macaques (2019) (2)
- Erratum: Contribution of CD8+ T cells to control of Mycobacterium tuberculosis infection (Journal of Immunology (2006) 176 (4296-4314)) (2006) (2)
- Copper-64-labeled CB-TE1K1P conjugates of MCP-1 for PET imaging of macrophages in tuberculosis granulomas (2014) (2)
- Infection tuberculosis Mycobacterium Cells In Vivo during + Macrophages In Vitro and That of CD 11 b TNF Influences Chemokine Expression of (2004) (2)
- Robust IgM responses following vaccination are associated with prevention of Mycobacterium tuberculosis infection in macaques (2021) (2)
- Corrigendum: Spatial Organization and Recruitment of Non-Specific T Cells May Limit T Cell-Macrophage Interactions Within Mycobacterium tuberculosis Granulomas (2021) (1)
- Predicting vaccine efficacy against tuberculosis using immunologic and radiologic markers in the non-human primate model (VAC7P.974) (2014) (1)
- infection in non-human primates and in tuberculosis patients (2012) (1)
- Immunodominance in Tuberculosis (2006) (1)
- Variations on the Cornell Murine Model Reactivation of Latent Tuberculosis (2013) (1)
- PET imaging of immune cells in a macaque tuberculosis model (2015) (1)
- The mutation rate of mycobacterial repetitive unit loci in strains of M. tuberculosisfrom cynomolgus macaque infection (2013) (1)
- Temporal and Spatial Analyses of TB Granulomas to Predict Long-Term Outcomes (2020) (1)
- Characterization of immunomodulatory cytokine IL-27 in tuberculosis infection. (2016) (1)
- Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques (2019) (1)
- MINIREVIEW Tuberculosis: Latency and Reactivation (2001) (1)
- Neutrophils in granulomas from Mycobacterium tuberculosis-infected macaques express granzyme B in response to mycobacterial products and pro-inflammatory signals (INC7P.406) (2014) (1)
- Identification and characterization of the T cell receptor (TCR) repertoire of the cynomolgus macaque (Macaca Fascicularis) (2022) (1)
- Characterizing the spectrum of latent Mtb infection in the cynomolgus macaque model: Clinical, immunologic, and PET CT features of evolution. (2023) (1)
- T cell transcription factor expression evolves as adaptive immunity matures in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques (2022) (1)
- ICAM‐1 expression is required for regulatory T cell localization in the lungs of M tuberculosis infected mice (2007) (0)
- JoAnne Flynn: BCG IV vaccination induces sterilising M.tb JoAnne IV vaccination induces sterilising M.tb (2022) (0)
- T cell cytokine profile of early tuberculosis infection and disease in Cynomolgus macaque model (P3335) (2013) (0)
- Blood Transcriptional Correlates of BCG-Induced Protection Against Tuberculosis in Rhesus Macaques (2022) (0)
- Reverse Immunology: An approach to identify Mtb antigens recognized by T cells (2022) (0)
- TNF and Tuberculosis (2006) (0)
- Distributable, Metabolic PET Reporting of Tuberculosis (2023) (0)
- At the Interface of Microbiology and Immunology (2020) (0)
- Limited frequency of cytokine-producing T cells in tuberculosis lung granulomas (MPF6P.736) (2014) (0)
- Arginase Isoforms Expression of Nitric Oxide Synthase and Populations of Macrophage Subsets and Granulomas Are Delineated by Distinct Microenvironments in Tuberculous (2013) (0)
- SIV and CD4 depletion distinctly reactivate latent Mycobacterium. tuberculosis infection (2020) (0)
- Epitope mapping of Mycobacterium tuberculosis proteins using a non-human primate model of infection (2019) (0)
- Blood transcriptional signatures of early tuberculosis infection and disease in cynomolgus macaque model (MPF6P.658) (2015) (0)
- CD4 T cells are important in protection against M. tuberculosis reinfection in cynomolgus macaques (2020) (0)
- Practical considerations for a TB controlled human infection model (TB-CHIM); the case for TB-CHIM in Africa, a systematic review of the literature and report of 2 workshop discussions in UK and Malawi (2023) (0)
- Profiling the airway in the macaque model of tuberculosis reveals variable microbial dysbiosis and alteration of community structure (2018) (0)
- Preclinical PET/CT imaging in a non-human primate model of tuberculosis (2009) (0)
- Temporal patterns in single cell immune profile of tuberculosis lung granulomas (2020) (0)
- Infection Mycobacterium tuberculosis during Antimicrobial Responses with Caseation Mediated - Early Host Immunity Control of Lesion Sterilization by Balancing Computational Modeling Predicts IL-10 (2014) (0)
- CD8 T cells are critical for control of acute M. tuberculosis infection in the non‐human primate (2008) (0)
- In silico identification and synthesis of a multi-drug loaded MOF for treating tuberculosis. (2022) (0)
- Cell Responses in Lymph Nodes Does Not Influence Priming of T tuberculosis Mycobacterium Inoculation Dose of (2013) (0)
- Response from Flynn and Bloom (1993) (0)
- Identifying third signal cytokines for development of differently functioning CD8 T cells in Mycobacterium tuberculosis infection (70.4) (2012) (0)
- Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas (2023) (0)
- Cynomolgus macaque neutrophils express IL-4 and IL-10 in response to Mycobacterium tuberculosis bacilli (2016) (0)
- Reviews and comment from the nature publishing group (2004) (0)
- CD8 T cells and Mycobacterium tuberculosis infection (2015) (0)
- Moving Target Understanding Latent Tuberculosis: A (2010) (0)
- Tuberculosis: Looking to the granuloma for answers (2011) (0)
- Bacteria load and hypoxia contribute to glucose uptake by macrophages and T cells in cynomolgus macaque granulomas (2022) (0)
- 2347. Blood Transcriptional Correlates of Vaccine-Induced Protection Against TB in Macaques (2022) (0)
- CD8 T cell response to Mycobacterium tuberculosis (2008) (0)
- Structural-functional relationships of TNF-alpha antagonists: next steps. (2007) (0)
- The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th Annual Research Conference, New Orleans, Louisiana, USA, 15-17 July 2001. Abstracts. (2002) (0)
- Infection Mycobacterium tuberculosis During T Cells + Development of Cytotoxic CD8 T Cells Are Required for the + CD4 (2001) (0)
- Mycobacterium tuberculosis Protects Against Challenge with Vaccination with the T Cell Antigen Mtb 8.4 (2001) (0)
- Preclinical PET/CT imaging in a biosafety level 3 (BSL-3) biocontainment environment (2009) (0)
- Prevention of tuberculosis in macaques after intravenous BCG immunization (2020) (0)
- Unraveling the role of fibrosis in the TB Granuloma (2019) (0)
- Priming of multifunctional Mycobacterium tuberculosis-specific CD8 T cells (132.13) (2009) (0)
- CT and 18F-FDG PET abnormalities in contacts with recent tuberculosis infections but negative chest X-ray (2022) (0)
- Deciphering multicellular microenvironment of tuberculosis lung granulomas associated with bacterial control using high-throughput single-cell mRNA sequencing (2019) (0)
- Binding Kinetics and Permeability among Anti-TNF Therapies Is Due to Drug Differential Risk of Tuberculosis Reactivation (2012) (0)
- Macrophages and neutrophils in necrotic granulomas from cynomolgus macaques and humans localize to distinct microenvironments and express nitric oxide synthase and arginase enzymes. (117.11) (2012) (0)
- Mycobacterium tuberculosis to Response Presentation in the Human Immune Dendritic Cell Trafficking and Antigen (2004) (0)
- Early in vivo infection dynamics in non-human primates infected with Mycobacterium tuberculosis (MPF3P.813) (2014) (0)
- Associated with Timing of Reactivation Infection Are Mycobacterium tuberculosis Cynomolgus Macaques with Latent Changes in T Cell Cytokine Responses in Simian Immunodeficiency Virus-Induced (2011) (0)
- Identification and characterization of the T cell receptor (TCR) repertoire of the cynomolgus macaque (Macaca Fascicularis) (2022) (0)
- JoAnne Flynn: BCG IV vaccination induces sterilising M.tb sterilising M.tb immunity.immunity. (2022) (0)
- The role of lymphocyte subsets in preventing tuberculosis following intravenous vaccination with BCG (2022) (0)
- Defining the role of CD8 T cell subsets in tuberculosis in non-human primates (2020) (0)
- mCherry-expressing Mycobacterium tuberculosis gives insight into host cell tropism and immune pressure at the single bacterium level in macaques with tuberculosis (2021) (0)
- CT-based attenuation correction for a pre-clinical PET/CT imaging platform (2009) (0)
- Immunogenicity of TB vaccine H56 in non-human primates (VAC4P.1113) (2015) (0)
- Faculty Opinions recommendation of Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory. (2001) (0)
- Immunomodulatory effects of IL-10 in tuberculosis granulomas of non-human primates (MPF1P.772) (2014) (0)
- Characterization of a potential host-directed therapy against TB in non-human primates (2019) (0)
- Concomitant immunity to M. tuberculosis infection (2022) (0)
- Estimating total numbers of Mycobacterium tuberculosis in lymph nodes of cynomolgus and rhesus macaques (2016) (0)
- Faculty Opinions recommendation of Separable effector T cell populations specialized for B cell help or tissue inflammation. (2001) (0)
- Sterilizing immunity: New opportunities for rational TB vaccine design (2021) (0)
- Transiently Diminished Levels of IFN-Mice Deficient in CD 4 T Cells Have (1999) (0)
- The precarious balance of immune response to Mycobacterium tuberculosis … are T regulatory cells predictive of infection outcome in a non-human primate model of tuberculosis? (43.5) (2007) (0)
- The HIV-1 Tat Team Gets Bigger (2010) (0)
- Optimizing tuberculosis treatment efficacy: comparing the standard regimen with Moxifloxacin-containing regimens (2022) (0)
- Predicting vaccine efficacy against tuberculosis using immunologic and radiologic measures in the non-human primate model (2016) (0)
- Coinfection tuberculosis M. specific CD4 T Cells during SIV/ - Mycobacterium tuberculosis Production by Monocyte-Derived IL-5 Reduces TNF (2013) (0)
- PermeabilityDue to Drug Binding Kinetics and Reactivation among Anti-TNF Therapies Is Differential Risk of Tuberculosis (2012) (0)
- Dynamic T Cell Responses During Tuberculosis--Studies in the Lungs (2004) (0)
- 1 Looking at an Oscillating Wire in a Soap Film (0)
- Primate PET scanner count rate analysis with [F-18]FDG dosed nonhuman primates (2009) (0)
- Multivariate Analysis Establishes Airway T Cells as a Correlate of IV BCG-Mediated Protection Against Tuberculosis in Rhesus Macaques (2022) (0)
- Drug treatment of tuberculosis diminishes but does not abolish the protection against secondary M. tuberculosis challenge (2019) (0)
- Vaccination with intravenous BCG protects macaques with pre-existing SIV infection from tuberculosis (2023) (0)
- Neutrophils in pulmonary granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques upregulate granzyme B expression in response to mycobacterial products and pro-inflammatory signals (P3058) (2013) (0)
- Mycobacterium tuberculosis-specific CD4 T cells expressing transcription factors associate with bacterial control in granulomas (2022) (0)
- Intravenous Bacille Calmette-Guerin provides protection across a dose spectrum in a Rhesus macaque model of tuberculosis (2019) (0)
- [18F]-FDG PET/CT characterisation of progressive HIV-associated tuberculosis (2016) (0)
- Which comes first Tregs or TB? (2008) (0)
- 1 Profiling Antibodies to Mycobacterium tuberculosis ( M . tb . ) by Multiplex Microbead 1 Suspension Arrays for Serodiagnosis of TB 2 (2007) (0)
- Vaccine-Elicited T cells are Important for Intravenous BCG Mediated Protection in a Rhesus macaque Model of Tuberculosis (2020) (0)
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