João Pedro de Magalhães
#58,256
Most Influential Person Now
Portuguese microbiologist and ageing researcher
João Pedro de Magalhães's AcademicInfluence.com Rankings
João Pedro de Magalhãesbiology Degrees
Biology
#5626
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#8152
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Microbiology
#468
World Rank
#529
Historical Rank
Genetics
#1255
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#1357
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Biochemistry
#2027
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#2169
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Biology
João Pedro de Magalhães's Degrees
- PhD Genetics Université de Namur
- Masters Biochemistry University of Porto
- Bachelors Biochemistry University of Porto
Why Is João Pedro de Magalhães Influential?
(Suggest an Edit or Addition)According to Wikipedia, Joao Pedro De Magalhaes is a Portuguese microbiologist. He studies aging through both computational and experimental approaches. His ultimate goal is to cure human aging. In 1999, he obtained his degree in Microbiology from Escola Superior de Biotecnologia. Under Olivier Toussaint, he obtained his PhD from the University of Namur in 2004. Then he did a postdoc in the George Church lab at Harvard Medical School from 2004 to 2008.
João Pedro de Magalhães's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Gene co-expression analysis for functional classification and gene–disease predictions (2017) (647)
- Meta-analysis of age-related gene expression profiles identifies common signatures of aging (2009) (616)
- Human Ageing Genomic Resources: Integrated databases and tools for the biology and genetics of ageing (2012) (505)
- A database of vertebrate longevity records and their relation to other life‐history traits (2009) (448)
- RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types (2019) (405)
- Human Ageing Genomic Resources: new and updated databases (2017) (374)
- An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts. (2007) (282)
- The role of DNA methylation in aging, rejuvenation, and age-related disease. (2012) (263)
- Insights into the Evolution of Longevity from the Bowhead Whale Genome (2015) (256)
- Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer (2016) (225)
- How ageing processes influence cancer (2013) (217)
- A review and appraisal of the DNA damage theory of ageing. (2011) (204)
- Stress, cell senescence and organismal ageing (2017) (202)
- The Human Ageing Genomic Resources: online databases and tools for biogerontologists (2009) (200)
- HAGR: the Human Ageing Genomic Resources (2004) (147)
- Genome-Environment Interactions That Modulate Aging: Powerful Targets for Drug Discovery (2012) (131)
- Next-generation sequencing in aging research: Emerging applications, problems, pitfalls and possible solutions (2010) (124)
- GenAge: a genomic and proteomic network map of human ageing (2004) (118)
- m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome (2020) (116)
- flowAI: automatic and interactive anomaly discerning tools for flow cytometry data (2016) (114)
- The Business of Anti-Aging Science. (2017) (111)
- GeneFriends: a human RNA-seq-based gene and transcript co-expression database (2014) (111)
- Cells discover fire: Employing reactive oxygen species in developmentand consequences for aging (2006) (105)
- The Influence of Genes on the Aging Process of Mice (2005) (105)
- Genomes optimize reproduction: aging as a consequence of the developmental program. (2005) (100)
- Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome (2012) (98)
- The DrugAge database of aging‐related drugs (2017) (97)
- RNA Sequencing Reveals Differential Expression of Mitochondrial and Oxidation Reduction Genes in the Long-Lived Naked Mole-Rat When Compared to Mice (2011) (93)
- A network pharmacology approach reveals new candidate caloric restriction mimetics in C. elegans (2015) (87)
- A comparison of human and mouse gene co-expression networks reveals conservation and divergence at the tissue, pathway and disease levels (2015) (86)
- A review of supervised machine learning applied to ageing research (2017) (86)
- Being cool: how body temperature influences ageing and longevity (2015) (86)
- Stress‐induced premature senescence in BJ and hTERT‐BJ1 human foreskin fibroblasts (2002) (85)
- Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity (2008) (85)
- LongevityMap: a database of human genetic variants associated with longevity. (2013) (85)
- Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease (2015) (85)
- From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing. (2004) (82)
- From humans to hydra: patterns of cancer across the tree of life (2018) (81)
- A meta-analysis of caloric restriction gene expression profiles to infer common signatures and regulatory mechanisms. (2012) (79)
- Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase (2004) (74)
- Enhancing Epitranscriptome Module Detection from m6A-Seq Data Using Threshold-Based Measurement Weighting Strategy (2018) (74)
- A multidimensional systems biology analysis of cellular senescence in aging and disease (2020) (74)
- The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations (2014) (73)
- Systematic analysis of the gerontome reveals links between aging and age-related diseases (2016) (73)
- The Digital Ageing Atlas: integrating the diversity of age-related changes into a unified resource (2014) (70)
- GeneFriends: An online co-expression analysis tool to identify novel gene targets for aging and complex diseases (2012) (67)
- Systems biology and longevity: an emerging approach to identify innovative anti-aging targets and strategies. (2010) (66)
- A data mining approach for classifying DNA repair genes into ageing-related or non-ageing-related (2011) (64)
- m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human (2020) (62)
- Programmatic features of aging originating in development: aging mechanisms beyond molecular damage? (2012) (62)
- Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization (2015) (58)
- Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities (2020) (58)
- Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence (2018) (57)
- Programmatic features of aging originating in development: aging mechanisms beyond molecular damage? (2012) (56)
- Accelerated protein evolution analysis reveals genes and pathways associated with the evolution of mammalian longevity (2013) (55)
- Biological Processes Modulating Longevity across Primates: A Phylogenetic Genome-Phenome Analysis (2018) (55)
- Dissecting the Gene Network of Dietary Restriction to Identify Evolutionarily Conserved Pathways and New Functional Genes (2012) (54)
- Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks (2012) (53)
- Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress‐induced premature senescence (2001) (52)
- RMDisease: a database of genetic variants that affect RNA modifications, with implications for epitranscriptome pathogenesis (2020) (52)
- A human tissue‐specific transcriptomic analysis reveals a complex relationship between aging, cancer, and cellular senescence (2019) (51)
- The effects of donor age on organ transplants: A review and implications for aging research (2018) (51)
- How ageing processes influence cancer (2013) (50)
- Cognitive aging as an extension of brain development: A model linking learning, brain plasticity, and neurodegeneration (2005) (50)
- Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging (2015) (49)
- A new approach for interpreting Random Forest models and its application to the biology of ageing (2018) (47)
- Mitochondrially encoded methionine is inversely related to longevity in mammals (2011) (45)
- From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing. (2004) (44)
- Analyses of human–chimpanzee orthologous gene pairs to explore evolutionary hypotheses of aging (2007) (43)
- Predicting the Pro-Longevity or Anti-Longevity Effect of Model Organism Genes with New Hierarchical Feature Selection Methods (2015) (40)
- miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer’s Disease (2020) (39)
- Targeting immune dysfunction in aging (2021) (39)
- The evolution of mammalian aging (2002) (38)
- The hoverfly and the wasp: A critique of the hallmarks of aging as a paradigm (2021) (38)
- Age-related gene-specific changes of A-to-I mRNA editing in the human brain (2010) (38)
- Gene Size Matters: An Analysis of Gene Length in the Human Genome (2021) (35)
- To help aging populations, classify organismal senescence (2019) (35)
- m5C-Atlas: a comprehensive database for decoding and annotating the 5-methylcytosine (m5C) epitranscriptome (2021) (35)
- A multidimensional systems biology analysis of cellular senescence in aging and disease (2019) (34)
- Open-minded scepticism: inferring the causal mechanisms of human ageing from genetic perturbations. (2005) (34)
- Telomeres and telomerase: a modern fountain of youth? (2004) (32)
- Cell resilience in species life spans: a link to inflammation? (2010) (31)
- Attention-based multi-label neural networks for integrated prediction and interpretation of twelve widely occurring RNA modifications (2021) (31)
- Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research. (2014) (31)
- The scientific quest for lasting youth: prospects for curing aging. (2014) (30)
- Machine learning for predicting lifespan-extending chemical compounds (2017) (30)
- An integrative analysis of the age-associated multi-omic landscape across cancers (2021) (30)
- Positive selection and gene duplications in tumour suppressor genes reveal clues about how cetaceans resist cancer (2020) (30)
- Winter is coming: the future of cryopreservation (2021) (29)
- Bioinformatics approaches for deciphering the epitranscriptome: Recent progress and emerging topics (2020) (29)
- Open-minded scepticism: inferring the causal mechanisms of human ageing from genetic perturbations (2005) (26)
- Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research (2014) (26)
- ConsRM: collection and large-scale prediction of the evolutionarily conserved RNA methylation sites, with implications for the functional epitranscriptome. (2021) (25)
- How bioinformatics can help reverse engineer human aging (2004) (25)
- Human Disease-Associated Mitochondrial Mutations Fixed in Nonhuman Primates (2005) (25)
- Fish oil supplements, longevity and aging (2016) (24)
- The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS (2021) (24)
- Species Selection in Comparative Studies of Aging and Antiaging Research (2006) (23)
- Is mammalian aging genetically controlled? (2004) (21)
- Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans (2017) (21)
- Circulating MicroRNAs in Young Patients with Acute Coronary Syndrome (2018) (20)
- Every gene can (and possibly will) be associated with cancer. (2021) (20)
- A review of the biomedical innovations for healthy longevity (2017) (20)
- Sex‐specific aging in animals: Perspective and future directions (2022) (19)
- Ageing transcriptome meta-analysis reveals similarities and differences between key mammalian tissues (2021) (18)
- Ageing-associated changes in the expression of lncRNAs in human tissues reflect a transcriptional modulation in ageing pathways (2019) (18)
- Ecological, biomedical and epidemiological approaches to understanding oxidative balance and ageing: what they can teach each other (2010) (18)
- A mathematical model of mortality dynamics across the lifespan combining heterogeneity and stochastic effects (2013) (17)
- Stress‐induced Premature Senescence (SIPS) (2005) (17)
- Molecular damage in aging (2021) (17)
- Topological Characterization of Human and Mouse m5C Epitranscriptome Revealed by Bisulfite Sequencing (2018) (16)
- Insights on cryoprotectant toxicity from gene expression profiling of endothelial cells exposed to ethylene glycol. (2015) (16)
- A Reassessment of Genes Modulating Aging in Mice Using Demographic Measurements of the Rate of Aging (2018) (15)
- Gathering insights on disease etiology from gene expression profiles of healthy tissues (2011) (15)
- Targeting aging mechanisms: pharmacological perspectives (2022) (14)
- A-to-I RNA editing does not change with age in the healthy male rat brain (2013) (14)
- Has gene duplication impacted the evolution of Eutherian longevity? (2016) (13)
- A scan for genes associated with cancer mortality and longevity in pedigree dog breeds (2020) (13)
- Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13 (2020) (13)
- Mutational Bias Plays an Important Role in Shaping Longevity-Related Amino Acid Content in Mammalian mtDNA-Encoded Proteins (2012) (13)
- Ageing research in the post-genome era: new technologies for an old problem. (2009) (12)
- m6A-TSHub: unveiling the context-specific m6A methylation and m6A-affecting mutations in 23 human tissues (2022) (11)
- Using deep learning to associate human genes with age-related diseases (2019) (11)
- scAgeCom: a murine atlas of age-related changes in intercellular communication inferred with the package scDiffCom (2021) (11)
- Endless paces of degeneration—applying comparative genomics to study evolution's moulding of longevity (2013) (11)
- Comparing enrichment analysis and machine learning for identifying gene properties that discriminate between gene classes (2020) (10)
- Reductions in hypothalamic Gfap expression, glial cells and α-tanycytes in lean and hypermetabolic Gnasxl-deficient mice (2016) (10)
- Genome‐Wide Patterns of Genetic Distances Reveal Candidate Loci Contributing to Human Population‐Specific Traits (2012) (10)
- Identification of polymorphisms in cancer patients that differentially affect survival with age (2017) (10)
- Ageing research in the post-genome era: new technologies for an old problem. (2009) (9)
- Ageing Transcriptome Meta-Analysis Reveals Similarities Between Key Mammalian Tissues (2019) (9)
- A proposal to sequence genomes of unique interest for research on aging. (2007) (9)
- The fog of genetics: what is known, unknown and unknowable in the genetics of complex traits and diseases (2019) (9)
- Longevity pharmacology comes of age. (2021) (8)
- MYCN/LIN28B/Let-7/HMGA2 pathway implicated by meta-analysis of GWAS in suppression of post-natal proliferation thereby potentially contributing to aging (2013) (8)
- Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine (2022) (8)
- WHISTLE Server: a high-accuracy genomic coordinate-based machine learning platform for RNA modification prediction. (2021) (8)
- Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection (2022) (8)
- The big, the bad and the ugly (2015) (8)
- The hyperfunction theory: An emerging paradigm for the biology of aging Ageing Research Reviews (2021) (7)
- RMDisease V2.0: an updated database of genetic variants that affect RNA modifications with disease and trait implication (2022) (7)
- Cellular reprogramming and the rise of rejuvenation biotech. (2022) (7)
- SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes (2020) (7)
- Alice's dilemma (2004) (7)
- Selection and local adaptation in capuchin monkeys revealed through fluorescence-activated cell sorting of feces (fecalFACS) (2020) (7)
- DirectRMDB: a database of post-transcriptional RNA modifications unveiled from direct RNA sequencing technology (2022) (7)
- An analysis and validation pipeline for large-scale RNAi-based screens (2013) (6)
- Ethical Perspectives in Biogerontology (2013) (6)
- The big, the bad and the ugly: Extreme animals as inspiration for biomedical research. (2015) (6)
- Bioinformatics in aging research: a workshop report. (2010) (6)
- A review of supervised machine learning applied to ageing research (2017) (5)
- Paternal genome effects on aging: evidence for a role of Rasgrf1 in longevity determination? (2011) (5)
- Age-associated differences in the cancer molecular landscape. (2022) (5)
- Paternal genome effects on aging: Evidence for a role of Rasgrf1 in longevity determination? (2011) (5)
- SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes (2020) (5)
- Evolution, structure and emerging roles of C1ORF112 in DNA replication, DNA damage responses, and cancer (2021) (5)
- Positive Selection and Enhancer Evolution Shaped Lifespan and Body Mass in Great Apes (2021) (5)
- GeneFriends 2021: Updated co-expression databases and tools for human and mouse genes and transcripts (2021) (4)
- Geographic encoding of transcripts enabled high-accuracy and isoform-aware deep learning of RNA methylation (2022) (4)
- Identifying Novel Osteoarthritis-Associated Genes in Human Cartilage Using a Systematic Meta-Analysis and a Multi-Source Integrated Network (2022) (4)
- A role for Ras signaling in modulating mammalian aging by the GH/IGF1 axis (2011) (4)
- GeneFriends: An online co-expression analysis tool to identify novel gene targets for aging and complex diseases (2012) (4)
- Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs. (2022) (3)
- Osh6 links yeast vacuolar functions to lifespan extension and TOR (2012) (3)
- A role for Ras signaling in modulating mammalian aging by the GH/IGF1 axis. (2011) (3)
- The evolution of ecological flexibility, large brains, and long lives: capuchin monkey genomics revealed with fecalFACS (2018) (3)
- Machine learning-based predictions of dietary restriction associations across ageing-related genes (2022) (3)
- In memory of Dr. Olivier Toussaint (2017) (3)
- A direct communication proposal to test the Zoo Hypothesis (2015) (3)
- A Human Tissue-Specific Transcriptomic Analysis Reveals that Ageing Hinders Cancer and Boosts Cellular Senescence (2019) (2)
- Integrative genomics of aging (2021) (2)
- Human disease-associated mitochondrial mutations fixed in nonhuman primates. (2005) (2)
- Human Ageing Genomic Resources: 2018 Update (2017) (2)
- An Integrative Analysis of the Age-Associated Genomic, Transcriptomic and Epigenetic Landscape across Cancers (2020) (2)
- Gene size matters: What determines gene length in the human genome? (2020) (2)
- 31. Cryoprotectant toxicity: Biochemical mechanisms and functional genomics (2015) (1)
- Intercellular communication analysis of the human retinal pigment epithelial and choroidal cells predicts pathways associated with aging, cellular senescence and age-related macular degeneration (2022) (1)
- Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome (2012) (1)
- The inherent challenges of classifying senescence—Response (2020) (1)
- Ageing as a software design flaw (2023) (1)
- Systematic analysis of the gerontome reveals links between aging and age-related diseases. (2016) (1)
- Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis. (2023) (1)
- The fog of genetics: Known unknowns and unknown unknowns in the genetics of complex traits and diseases (2019) (1)
- Is mammalian aging genetically controlled? (2003) (1)
- Population genomics of white faced capuchin monkeys (Cebus capucinus imitator) with unbiased fecal genomes (2018) (0)
- UNCORRECTED PROOF 1 A mathematical model of mortality dynamics across the lifespan 2 combining heterogeneity and stochastic effects (2013) (0)
- Machine-learning-based predictions of caloric restriction associations across ageing-related genes (2021) (0)
- Omics approaches and large-scale data analysis in ageing research 1 (2017) (0)
- Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging (2015) (0)
- Being cool: how body temperature influences ageing and longevity (2015) (0)
- Reductions in hypothalamic Gfap expression, glial cells and α-tanycytes in lean and hypermetabolic Gnasxl-deficient mice (2016) (0)
- Elaborating deconvolution of immune cell sub-populations from mixed transcriptomic data (2016) (0)
- Mathematical Study of Mortality Dynamics in Heterogeneous Population Composed of Subpopulations Following the Exponential Law (2015) (0)
- Vulnerability of progeroid smooth muscle cells to biomechanical forces is 1 mediated by MMP 13 2 3 (2020) (0)
- A method for the permeabilization of live Drosophila melanogaster larvae to small molecules and cryoprotectants (2019) (0)
- A SYSTEMATIC META-ANALYSIS AND MULTI-SOURCE INFORMATION NETWORK IDENTIFY NOVEL OSTEOARTHRITIS-ASSOCIATED GENES (2022) (0)
- Proposal to Sequence an Organism of Unique Interest for Research on Aging : Heterocephalus glaber , the Naked Mole-Rat (2008) (0)
- PICKER-HG: a web server using random forests for classifying human genes into categories (2019) (0)
- Rilmenidine mimics caloric restriction via the nischarin I1-imidazoline receptor to extend lifespan in C. elegans (2021) (0)
- Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection (2022) (0)
- Winter is coming: the future of cryopreservation (2021) (0)
- Accelerated protein evolution analysis reveals genes and pathways associated with the evolution of mammalian longevity (2011) (0)
- Meet the Editorial Board Members (2015) (0)
- Evidence of a pan-tissue decline in stemness during human aging (2023) (0)
- Proposal to Sequence Genomes of Unique Interest for Research on Aging: Heterocephalus glaber, Cebus capucinus, and Balaena mysticetus (2007) (0)
- Single-cell gene regulation across aging tissues (2022) (0)
- Pan-cancer transcriptomic analysis reveals a tissue-specific loss of identity (2022) (0)
- Interpretable Ensembles of Classifiers for Uncertain Data with Bioinformatics Applications. (2022) (0)
- Trans Cohorts Metabolomic Modulation Following Long-Term Successful Therapy in HIV-Infection (2021) (0)
- Skin Aging in Long-Lived Naked Mole-Rats is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes. (2022) (0)
- A-to-I RNA editing does not change with age in the healthy male rat brain (2013) (0)
- Predicting Lifespan-Extending Chemical Compounds with Machine Learning and Biologically Interpretable Features (2022) (0)
- List of contributors (2021) (0)
- A comparison of human and mouse gene co-expression networks reveals conservation and divergence at the tissue, pathway and disease levels (2015) (0)
- Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1‐imidazoline receptor (2023) (0)
- GeneFriends: gene co-expression databases and tools for humans and model organisms (2022) (0)
- Mutational Bias Plays an Important Role in Shaping Longevity-Related Amino Acid Content in Mammalian mtDNA-Encoded Proteins (2012) (0)
- A scan for genes associated with cancer mortality and longevity in pedigree dog breeds (2020) (0)
- In memory of Dr. Olivier Toussaint (2017) (0)
- The genetics of a long life (2022) (0)
- Epigenetic fidelity in complex biological systems and implications for ageing (2023) (0)
- Machine learning-based predictions of dietary restriction associations across ageing-related genes (2022) (0)
- Chapter 13 Ethical Perspectives in Biogerontology (2012) (0)
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What Schools Are Affiliated With João Pedro de Magalhães?
João Pedro de Magalhães is affiliated with the following schools:
