Joel Dudley
#91,718
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American medical researcher
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Joel Dudleylaw Degrees
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Joel Dudleycomputer-science Degrees
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Joel Dudley's Degrees
- PhD Biomedical Informatics Stanford University
- Doctorate Medicine Stanford University
Why Is Joel Dudley Influential?
(Suggest an Edit or Addition)According to Wikipedia, Joel Dudley is currently Associate Professor of Genetics and Genomic Sciences and founding Director of the Institute for Next Generation Healthcare at the Icahn School of Medicine at Mount Sinai. In March, 2018 Dr. Dudley was named Executive Vice President for Precision Health for the Mount Sinai Health System . In 2017 he was awarded an Endowed Professorship by Mount Sinai in Biomedical Data Science. Prior to Mount Sinai, he held positions as Co-founder and Director of Informatics at NuMedii, Inc. and Consulting Professor of Systems Medicine in the Department of Pediatrics at Stanford University School of Medicine. His work is focused at the nexus of -omics, digital health, artificial intelligence , scientific wellness, and healthcare delivery. His work has been featured in the Wall Street Journal, Scientific American, MIT Technology Review, CNBC, and other popular media outlets. He was named in 2014 as one of the 100 most creative people in business by Fast Company magazine. He is co-author of the book Exploring Personal Genomics from Oxford University Press. Dr. Dudley received a BS in Microbiology from Arizona State University and an MS and PhD in Biomedical Informatics from Stanford University School of Medicine.
Joel Dudley's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. (2007) (29050)
- MEGA: A biologist-centric software for evolutionary analysis of DNA and protein sequences (2008) (3327)
- Molecular Evolutionary Genetics Analysis (2007) (1926)
- Deep learning for healthcare: review, opportunities and challenges (2018) (1367)
- Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records (2016) (1167)
- Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes (2012) (1128)
- TimeTree: a public knowledge-base of divergence times among organisms (2006) (1109)
- Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia (2016) (831)
- Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data (2011) (696)
- Clinical assessment incorporating a personal genome (2010) (692)
- Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease (2011) (517)
- Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus (2018) (476)
- Identification of type 2 diabetes subgroups through topological analysis of patient similarity (2015) (448)
- Exploiting drug-disease relationships for computational drug repositioning (2011) (432)
- Artificial Intelligence in Cardiology. (2018) (428)
- Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets (2010) (320)
- A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. (2013) (301)
- Machine learning in cardiovascular medicine: are we there yet? (2018) (288)
- Machine-Learning Algorithms to Automate Morphological and Functional Assessments in 2D Echocardiography. (2016) (263)
- Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics (2015) (248)
- Necroptosis activation in Alzheimer's disease (2017) (239)
- Natural Language Processing of Clinical Notes on Chronic Diseases: Systematic Review (2019) (214)
- In silico methods for drug repurposing and pharmacology (2016) (211)
- L1000CDS2: LINCS L1000 characteristic direction signatures search engine (2016) (200)
- Deep learning predicts hip fracture using confounding patient and healthcare variables (2018) (185)
- Androgen Deprivation Therapy and Future Alzheimer's Disease Risk. (2016) (161)
- The Asthma Mobile Health Study, a large-scale clinical observational study using ResearchKit (2017) (160)
- Translational bioinformatics in the era of real-time biomedical, health care and wellness data streams (2016) (155)
- Phased Whole-Genome Genetic Risk in a Family Quartet Using a Major Allele Reference Sequence (2011) (149)
- Genome-wide significant loci: how important are they? Systems genetics to understand heritability of coronary artery disease and other common complex disorders. (2015) (147)
- Multiplex qPCR discriminates variants of concern to enhance global surveillance of SARS-CoV-2 (2021) (146)
- Unifying immunology with informatics and multiscale biology (2014) (144)
- In silico research in the era of cloud computing (2010) (129)
- Disease signatures are robust across tissues and experiments (2009) (127)
- Type 2 Diabetes Risk Alleles Demonstrate Extreme Directional Differentiation among Human Populations, Compared to Other Diseases (2012) (117)
- Gold Nanoparticle Reprograms Pancreatic Tumor Microenvironment and Inhibits Tumor Growth. (2016) (115)
- Predictive Modeling of Hospital Readmission Rates Using Electronic Medical Record-Wide Machine Learning: A Case-Study Using Mount Sinai Heart Failure Cohort (2017) (114)
- A targetable GATA2-IGF2 axis confers aggressiveness in lethal prostate cancer. (2015) (110)
- The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report (2016) (105)
- Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease (2016) (102)
- Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS (2018) (100)
- Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach. (2016) (99)
- Translational bioinformatics in the cloud: an affordable alternative (2010) (99)
- Cognitive Machine-Learning Algorithm for Cardiac Imaging: A Pilot Study for Differentiating Constrictive Pericarditis From Restrictive Cardiomyopathy. (2016) (98)
- Early life stress alters transcriptomic patterning across reward circuitry in male and female mice (2019) (98)
- Genomic and network patterns of schizophrenia genetic variation in human evolutionary accelerated regions. (2015) (93)
- Systematic functional regulatory assessment of disease-associated variants (2013) (89)
- Differentially Expressed RNA from Public Microarray Data Identifies Serum Protein Biomarkers for Cross-Organ Transplant Rejection and Other Conditions (2010) (87)
- Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States (2021) (83)
- Computational and experimental advances in drug repositioning for accelerated therapeutic stratification. (2015) (78)
- Phylomedicine: an evolutionary telescope to explore and diagnose the universe of disease mutations. (2011) (77)
- Proposed Requirements for Cardiovascular Imaging-Related Machine Learning Evaluation (PRIME): A Checklist: Reviewed by the American College of Cardiology Healthcare Innovation Council. (2020) (76)
- Development and clinical application of an integrative genomic approach to personalized cancer therapy (2016) (76)
- FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease (2008) (76)
- Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology (2017) (75)
- Disease Heritability Inferred from Familial Relationships Reported in Medical Records (2018) (71)
- Bioinformatics software for biologists in the genomics era (2007) (70)
- Mapping the effects of drugs on the immune system (2015) (70)
- Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning (2017) (68)
- Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. (2016) (68)
- Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine (2017) (67)
- Extreme Evolutionary Disparities Seen in Positive Selection across Seven Complex Diseases (2010) (65)
- Open chromatin profiling of human postmortem brain infers functional roles for non‐coding schizophrenia loci (2017) (64)
- Identification of Discriminating Biomarkers for Human Disease Using Integrative Network Biology (2008) (62)
- Drug Discovery in a Multidimensional World: Systems, Patterns, and Networks (2010) (61)
- Age-stratified risk of unexpected uterine sarcoma following surgery for presumed benign leiomyoma. (2015) (60)
- Automated disease cohort selection using word embeddings from Electronic Health Records (2018) (59)
- Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. (2017) (58)
- Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits (2019) (57)
- Toward clinical genomics in everyday medicine: perspectives and recommendations (2016) (57)
- Isolation and Identification of the Follicular Microbiome: Implications for Acne Research. (2017) (57)
- Expression-based drug screening of neural progenitor cells from individuals with schizophrenia (2018) (56)
- A Quick Guide for Developing Effective Bioinformatics Programming Skills (2009) (55)
- Automated Detection of Off-Label Drug Use (2014) (54)
- REDD1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoids (2014) (54)
- ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression (2011) (53)
- Association of Hemoglobin A1c Levels With Use of Sulfonylureas, Dipeptidyl Peptidase 4 Inhibitors, and Thiazolidinediones in Patients With Type 2 Diabetes Treated With Metformin (2018) (51)
- Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden (2018) (51)
- Intracoronary Imaging, Cholesterol Efflux, and Transcriptomes After Intensive Statin Treatment: The YELLOW II Study. (2017) (50)
- Alterations in innate immunity and epithelial cell differentiation are the molecular pillars of hidradenitis suppurativa (2019) (50)
- Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain (2015) (49)
- The next generation of precision medicine: observational studies, electronic health records, biobanks and continuous monitoring. (2018) (49)
- Deep representation learning of electronic health records to unlock patient stratification at scale (2020) (49)
- Disease Risk Factors Identified Through Shared Genetic Architecture and Electronic Medical Records (2014) (48)
- EHDViz: clinical dashboard development using open-source technologies (2016) (48)
- Deep Learning to Predict Patient Future Diseases from the Electronic Health Records (2016) (47)
- Cognitive Machine-Learning Algorithm for Cardiac ImagingCLINICAL PERSPECTIVE (2016) (47)
- Integrative network analysis identifies novel drivers of pathogenesis and progression in newly diagnosed multiple myeloma (2017) (46)
- Mutation-derived Neoantigen-specific T-cell Responses in Multiple Myeloma (2019) (45)
- Content-based microarray search using differential expression profiles (2010) (45)
- Automated cell type discovery and classification through knowledge transfer (2017) (44)
- Supplementary Materials for Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease (2011) (43)
- Human genomic disease variants: A neutral evolutionary explanation (2012) (43)
- Overcoming obstacles to repurposing for neurodegenerative disease (2014) (42)
- PCR assay to enhance global surveillance for SARS-CoV-2 variants of concern (2021) (41)
- High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors (2017) (41)
- Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks (2016) (40)
- MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data. (2018) (38)
- Enabling Integrative Genomic Analysis of High Impact Human Diseases Through Text Mining (2007) (37)
- Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci (2016) (36)
- Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics. (2015) (32)
- Uncovering exposures responsible for birth season – disease effects: a global study (2017) (32)
- STORMSeq: An Open-Source, User-Friendly Pipeline for Processing Personal Genomics Data in the Cloud (2014) (31)
- Deep representation learning of electronic health records to unlock patient stratification at scale. (2020) (30)
- Predicting age by mining electronic medical records with deep learning characterizes differences between chronological and physiological age (2017) (30)
- MEWS++: Enhancing the Prediction of Clinical Deterioration in Admitted Patients through a Machine Learning Model (2020) (29)
- Reflecting health: smart mirrors for personalized medicine (2018) (29)
- Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells (2017) (28)
- Novel Therapeutics Identification for Fibrosis in Renal Allograft Using Integrative Informatics Approach (2017) (27)
- Transcriptional Profiling of Egg Allergy and Relationship to Disease Phenotype (2016) (27)
- Accelerators: Sparking Innovation and Transdisciplinary Team Science in Disparities Research (2017) (27)
- Artificial Intelligence-Based Assessment of Left Ventricular Filling Pressures From 2-Dimensional Cardiac Ultrasound Images. (2017) (27)
- Cell-specific prediction and application of drug-induced gene expression profiles (2017) (27)
- Rapamycin Modulates Glucocorticoid Receptor Function, Blocks Atrophogene REDD1, and Protects Skin from Steroid Atrophy. (2018) (26)
- Translational Bioinformatics Approaches to Drug Development. (2013) (26)
- Data-Driven Identification of Risk Factors of Patient Satisfaction at a Large Urban Academic Medical Center (2016) (26)
- Interpretome: A Freely Available, Modular, and Secure Personal Genome Interpretation Engine (2011) (25)
- PI3K inhibitors protect against glucocorticoid-induced skin atrophy (2019) (25)
- Personalized medicine: from genotypes, molecular phenotypes and the quantified self, towards improved medicine. (2014) (25)
- An Integrative Pipeline for Multi-Modal Discovery of Disease Relationships (2014) (23)
- Genomic Analysis of Kidney Allograft Injury Identifies Hematopoietic Cell Kinase as a Key Driver of Renal Fibrosis. (2017) (23)
- Predicting Future Cardiovascular Events in Patients With Peripheral Artery Disease Using Electronic Health Record Data (2019) (23)
- Precision Medicine for Relapsed Multiple Myeloma on the Basis of an Integrative Multiomics Approach (2018) (22)
- Designing Robust N-of-1 Studies for Precision Medicine: Simulation Study and Design Recommendations (2019) (22)
- Interpreting functional effects of coding variants: challenges in proteome-scale prediction, annotation and assessment (2016) (22)
- PatientExploreR: an extensible application for dynamic visualization of patient clinical history from electronic health records in the OMOP common data model (2019) (22)
- Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington’s Disease (2016) (21)
- Regulatory T-cell Genes Drive Altered Immune Microenvironment in Adult Solid Cancers and Allow for Immune Contextual Patient Subtyping (2017) (21)
- An integrative method for scoring candidate genes from association studies: application to warfarin dosing (2010) (19)
- MicroRNA‐195 controls MICU1 expression and tumor growth in ovarian cancer (2020) (19)
- Evolutionary meta-analysis of association studies reveals ancient constraints affecting disease marker discovery. (2012) (19)
- Privacy-Preserving Methods for Feature Engineering Using Blockchain: Review, Evaluation, and Proof of Concept (2019) (19)
- Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States (2021) (19)
- Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy (2018) (18)
- Evaluation of direct-to-consumer low-volume lab tests in healthy adults. (2016) (18)
- Leveraging Big Data to Transform Drug Discovery. (2019) (17)
- Pharmacological risk factors associated with hospital readmission rates in a psychiatric cohort identified using prescriptome data mining (2018) (17)
- Building a Secure Biomedical Data Sharing Decentralized App (DApp): Tutorial (2019) (17)
- Evaluation of direct-to-consumer low-volume lab tests in healthy adults. (2016) (17)
- Institutional profile: translational pharmacogenomics at the Icahn School of Medicine at Mount Sinai. (2017) (17)
- Dynamism in gene expression across multiple studies. (2010) (16)
- Arti fi cial Intelligence in Cardiology (2018) (16)
- Exploring Personal Genomics (2013) (16)
- The whole is greater than the sum of its parts: combining classical statistical and machine intelligence methods in medicine (2018) (15)
- Scaling structural learning with NO-BEARS to infer causal transcriptome networks (2019) (15)
- Integrative Analysis of Disease Signatures Shows Inflammation Disrupts Juvenile Experience-Dependent Cortical Plasticity (2016) (15)
- Replicating Cardiovascular Condition-Birth Month Associations (2016) (15)
- Patient similarity network of newly diagnosed multiple myeloma identifies patient subgroups with distinct genetic features and clinical implications (2020) (15)
- Integrative network modeling approaches to personalized cancer medicine. (2015) (15)
- Computational prediction and experimental validation associating FABP-1 and pancreatic adenocarcinoma with diabetes (2011) (15)
- Exploring the Reproducibility of Probabilistic Causal Molecular Network Models> (2017) (15)
- Integrative Approach to Pain Genetics Identifies Pain Sensitivity Loci across Diseases (2012) (14)
- Identifying Acute Low Back Pain Episodes in Primary Care Practice From Clinical Notes: Observational Study (2020) (14)
- Comparison of automated and human assignment of MeSH terms on publicly-available molecular datasets (2011) (14)
- Identification of cell surface targets through meta-analysis of microarray data. (2012) (14)
- Modern Methods for Delineating Metagenomic Complexity. (2015) (14)
- Influence of age on androgen deprivation therapy-associated Alzheimer’s disease (2016) (14)
- Clinical evaluation incorporating a personal genome (2010) (14)
- Automated phenotyping of patients with non-alcoholic fatty liver disease reveals clinically relevant disease subtypes (2019) (13)
- miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease (2020) (13)
- The Rapid Prediction of Carbapenem Resistance in Patients With Klebsiella pneumoniae Bacteremia Using Electronic Medical Record Data (2018) (13)
- Transcriptomic network interactions in the human skin treated with topical glucocorticoid clobetasol propionate. (2019) (13)
- Causal inference on electronic health records to assess blood pressure treatment targets: An application of the parametric g formula (2018) (13)
- High-Throughput Identification of the Plasma Proteomic Signature of Inflammatory Bowel Disease (2018) (13)
- Sepsis in the era of data-driven medicine: personalizing risks, diagnoses, treatments and prognoses (2019) (13)
- Longitudinal Autonomic Nervous System Measures Correlate With Stress and Ulcerative Colitis Disease Activity and Predict Flare. (2020) (13)
- Reply: Deep Learning With Unsupervised Feature in Echocardiographic Imaging. (2017) (12)
- Longitudinal data in peripheral blood confirm that PM20D1 is a quantitative trait locus (QTL) for Alzheimer’s disease and implicate its dynamic role in disease progression (2020) (12)
- Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia (2018) (12)
- Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits (2019) (10)
- Critical period plasticity-related transcriptional aberrations in schizophrenia and bipolar disorder (2019) (10)
- Weighted Gene Co-Expression Network Analysis (WGCNA) Identifies Highly Proliferative Myeloma Subgroup Responsive to CDK4/ARK5 Inhibition (2014) (10)
- Adaptive Landscape of Protein Variation in Human Exomes (2018) (10)
- Phe2vec: Automated disease phenotyping based on unsupervised embeddings from electronic health records (2020) (10)
- Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans (2019) (9)
- Sleep in the Natural Environment: A Pilot Study (2020) (9)
- Estimate of disease heritability using 7.4 million familial relationships inferred from electronic health records (2016) (9)
- Intracoronary Imaging, Cholesterol Efflux, and Transcriptomics after Intensive Statin Treatment in Diabetes (2017) (9)
- Molecular systems evaluation of oligomerogenic APPE693Q and fibrillogenic APPKM670/671NL/PSEN1Δexon9 mouse models identifies shared features with human Alzheimer's brain molecular pathology (2015) (9)
- Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy. (2019) (9)
- Important role of kallikrein 6 for the development of keratinocyte proliferative resistance to topical glucocorticoids (2016) (9)
- Integrative bioinformatics identifies postnatal lead (Pb) exposure disrupts developmental cortical plasticity (2018) (9)
- Loss-of-function of neuroplasticity-related genes confers risk for human neurodevelopmental disorders (2018) (9)
- A Network-Biology Informed Computational Drug Repositioning Strategy to Target Disease Risk Trajectories and Comorbidities of Peripheral Artery Disease (2018) (8)
- Erratum: Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells (Cell Reports (2016) 15(5) (1024–1036) (S2211124716303965) (10.1016/j.celrep.2016.03.090)) (2017) (8)
- Processing of Electronic Health Records using Deep Learning: A review (2018) (8)
- Latent physiological factors of complex human diseases revealed by independent component analysis of clinarrays (2010) (8)
- Biomarker and drug discovery for gastroenterology through translational bioinformatics. (2010) (8)
- Systems Medicine Approaches to Improving Understanding, Treatment, and Clinical Management of Neuroendocrine Prostate Cancer. (2016) (8)
- A transcriptomic model to predict increase in fibrous cap thickness in response to high-dose statin treatment: Validation by serial intracoronary OCT imaging (2019) (8)
- Clarifying the Potential Role of Microbes in Alzheimer’s Disease (2019) (8)
- Improved gastrointestinal health for irritable bowel syndrome with metagenome-guided interventions (2020) (8)
- Matching Cancer Genomes to Established Cell Lines for Personalized Oncology (2011) (8)
- Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin (2020) (8)
- Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis. (2022) (7)
- fragilityindex: An R Package for Statistical Fragility Estimates in Biomedicine (2019) (7)
- e-GRASP: an integrated evolutionary and GRASP resource for exploring disease associations (2016) (6)
- IMAGING BASED BIG DATA AND MACHINE LEARNING FRAMEWORK FOR RAPID PHENOTYPING OF LEFT VENTRICULAR DIASTOLIC FUNCTION (2016) (6)
- Integrative genomic meta-analysis reveals novel molecular insights into cystic fibrosis and ΔF508-CFTR rescue (2020) (6)
- Lyme Disease Patient Trajectories Learned from Electronic Medical Data for Stratification of Disease Risk and Therapeutic Response (2019) (6)
- An additional drug repurposing study for hidradenitis suppurativa/acne inversa (2020) (6)
- Drug Repositioning : Approaches and Applications for Neurotherapeutics (2017) (5)
- Longitudinal data in peripheral blood confirm that PM20D1 is a quantitative trait locus (QTL) for Alzheimer’s disease and implicate its dynamic role in disease progression (2020) (5)
- CANDI: an R package and Shiny app for annotating radiographs and evaluating computer-aided diagnosis (2018) (5)
- KRCC1: A potential therapeutic target in ovarian cancer (2019) (5)
- Automatic processing of Electronic Medical Records using Deep Learning (2018) (4)
- E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients (2018) (4)
- Enhancing high-content imaging for studying microtubule networks at large-scale (2019) (4)
- A Novel Approach to Safer Glucocorticoid Receptor–Targeted Anti-lymphoma Therapy via REDD1 (Regulated in Development and DNA Damage 1) Inhibition (2020) (4)
- Evaluation of patient re-identification using laboratory test orders and mitigation via latent space variables (2018) (4)
- Predictive Modelling of Susceptibility to Substance Abuse, Mortality and Drug-Drug Interactions in Opioid Patients (2021) (4)
- Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis (2021) (3)
- Molecular systems evaluation of oligomerogenic APPE693Q and fibrillogenic APPKM670/671NL/PSEN1Δexon9 mouse models identifies shared features with human Alzheimer’s brain molecular pathology (2016) (3)
- Correction: Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden (2018) (3)
- Corrigendum: Unifying immunology with informatics and multiscale biology (2014) (3)
- Patient Similarity Network of Multiple Myeloma Identifies Patient Sub-groups with Distinct Genetic and Clinical Features (2020) (3)
- Predictive modeling of susceptibility to substance abuse, mortality and drug-drug interactions in opioid patients (2018) (3)
- Deep phenotyping predicts Huntington's genotype (2016) (3)
- Further evidence of increased human Herpesvirus in Alzheimer’s disease (2019) (3)
- Rapid Therapeutic Recommendations in the Context of a Global Public Health Crisis using Translational Bioinformatics Approaches: A proof-of-concept study using Nipah Virus Infection (2018) (3)
- Meta-analysis of Cytometry Data Reveals Racial Differences in Immune Cells (2017) (3)
- Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci. (2018) (3)
- Integrative chemogenomic analysis identifies small molecules that partially rescue ΔF508‐CFTR for cystic fibrosis (2021) (2)
- A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report (2018) (2)
- Racial and Sex Differences in Stroke Risk in Patients With Atrial Fibrillation. (2019) (2)
- Healthcare Data Mining with Matrix Models (2016) (2)
- Cell-Type Specific open Chromatin Profiling in Human Postmortem Brain Infers Functional Roles For Non-Coding Schizophrenia LOCI (2016) (2)
- Deep learning-based brain transcriptomic signatures associated with the neuropathological and clinical severity of Alzheimer’s disease (2021) (2)
- Compendia of Public Gene Expression Data Discovery and Preclinical Validation of Drug Indications Using (2011) (2)
- Single-Cell RNA Sequencing Reveals Distinct Transcriptomic Profiles of Multiple Myeloma with Implications for Personalized Medicine (2017) (2)
- Abstract 4610: A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors (2014) (2)
- Deciphering Neuronal Broad Histone H3k4me3 Domains Associated with Gene-Regulatory Networks and Conserved Epigenomic Landscapes In The Human Brain (2017) (2)
- Prioritizing Small Molecule as Candidates for Drug Repositioning using Machine Learning (2018) (2)
- A Wipe-Based Stool Collection and Preservation Kit for Microbiome Community Profiling (2021) (2)
- Increased HLA-E Expression Correlates with Early Relapse in Multiple Myeloma (2018) (2)
- Network Modeling Reveals CDC42BPA and CLEC11A As Novel Driver Genes of t(4; 14) Multiple Myeloma (2016) (2)
- Clonal Evolution in Newly Diagnosed Multiple Myeloma Patients: A Follow-up Study from the Mmrf Commpass Genomics Project (2017) (2)
- An Integrative Informatics Approach to Identify Drug Targets and Therapies for Chronic Allograft Nephropathy After Kidney Transplantation.: Abstract# 2928 (2014) (1)
- A MACHINE LEARNING MODEL PREDICTS INDIVIDUALS WHO IMPROVE CORONARY ARTERY PLAQUE FIBROUS CAP THICKNESS FOLLOWING HIGH-INTENSITY STATIN THERAPY (2018) (1)
- Pleiotropic Variability Score: A Genome Interpretation Metric to Quantify Phenomic Associations of Genomic Variants (2021) (1)
- A MACHINE LEARNING MODEL PREDICTS INDIVIDUALS WHO IMPROVE CORONARY ARTERY PLAQUE FIBROUS CAP THICKNESS FOLLOWING HIGH-INTENSITY STATIN THERAPY (2018) (1)
- Designing robust N-of-1 studies for precision medicine (2018) (1)
- Reply to R.L. Bowen et al, M. Froehner et al, J.L. Leow et al, and C. Brady et al. (2016) (1)
- Multiscale analysis of acne connects molecular subnetworks with disease status (2019) (1)
- A Machine Learning Approach Identifies a 30-Gene Model That Predicts Sensitivity to Selinexor in Multiple Myeloma (2019) (1)
- A Marketplace for Health: Opportunities and Challenges for Biomedical Blockchains (Preprint) (2019) (1)
- Validation of a transcriptome-based assay for classifying cancers of unknown primary origin (2022) (1)
- Erratum to: e-GRASP: an integrated evolutionary and GRASP resource for exploring disease associations (2017) (1)
- Quantifying multi-ethnic representation in genetic studies of high mortality diseases (2012) (1)
- Saracatinib Is a Potential Novel Therapeutic for Pulmonary Fibrosis (2020) (1)
- Integrative Network Analysis of Newly Diagnosed Multiple Myeloma Identifies a Novel RNA-Seq Based High Riskgene Signature (2016) (1)
- Identification of therapeutic targets from genetic association studies using hierarchical component analysis (2020) (1)
- Learning and Mapping Lyme Disease Patient Trajectories from Electronic Medical Data for Stratification of Disease Risk and Therapeutic Response (2017) (1)
- Abstract 19489: Pharmacological Factors Associated With Congestive Heart Failure Hospital Readmission: A Case-Study Using 15,768 Heart Failure Patients From Two Health Systems (2016) (1)
- Application of I-COMO device towards geographic disease enrichment pattern revealed from electronic medical record at a large Urban academic medical center (2017) (0)
- Getting started with personal genomics (2013) (0)
- Rare and novel variants (2013) (0)
- Su1858 Integrative Networks Identify Novel Regulators of Susceptibility and Pathogenesis of Inflammatory Bowel Disease (2016) (0)
- 553 Sexual dimorphism in adverse effects of topical glucocorticoids is driven by the differential regulation of atrophogene REDD1 in male and female skin (2017) (0)
- Bioconjugated Lipid Polymer Hybrid Nanoparticles Targeting Myocardial Ischemic Reperfusion Injury to Reduce Infarction Size (2015) (0)
- BCI‐838, an orally active mGluR2/3 antagonist pro‐drug, mimics the beneficial effects of physical exercise on neurogenesis, behavior and exercise‐related molecular pathways in an Alzheimer’s disease mouse model (2022) (0)
- Dudley 1..6 (2011) (0)
- Rolling up codes for TKA (2018) (0)
- 407 Novel transcriptomic network interactions in the human skin treated with topical glucocorticoid (2019) (0)
- 17: MEWS++: PREDICTING CLINICAL DETERIORATION IN ADMITTED PATIENTS USING A NOVEL MACHINE LEARNING MODEL (2020) (0)
- Abstract 4307: Influence of age on androgen deprivation therapy-associated Alzheimer's disease (2016) (0)
- NBTS 09Novel insights on the molecular targets of environmental exposures during pregnancy using placental multi'omics data integration in the National Children's Study (NCS) (2014) (0)
- Personal genomics and the environment (2013) (0)
- 481 Isolating and identifying the acne skin microbiome (2016) (0)
- An Integrative Network Approach for Genomic Discovery and Personalized Therapy in Relapsed Multiple Myeloma (2014) (0)
- Cross-TissueRegulatory G eneNetworks in Coronary Artery Disease Graphical Abstract Highlights (2016) (0)
- Genetic trait associations (2013) (0)
- EFFECT OF ESCIN, THE ACTIVE INGREDIENT OF HORSE CHESTNUT SEED EXTRACT ON ATHEREROSCLEROTIC PLAGUE STABILIZATION (2021) (0)
- Identification and genetic validation of drug-comorbidity interactions in type 2 diabetes using data-driven disease trajectory analysis (2019) (0)
- Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in In Vitro, In Vivo and Ex Vivo Models of Pulmonary Fibrosis (2022) (0)
- Abstract 10647: Translational Systems Genetics, Electronic Medical Record Analysis, and Molecular Imaging Reveal That the Antidepressant Trazodone Reduces Atherosclerosis as Well as Statins: Drug Discovery by Repurposing of Proven Safe Drugs (2018) (0)
- Visualizing personal genomics (2013) (0)
- BIOCHEMICAL VALIDATION OF PIPERLONGUMINE AS A POTENT THERAPEUTIC AGAINST NEUROENDOCRINE PROSTATE CANCER: PD37‐10 (2017) (0)
- Orally active mGluR2/3 metabotropic antagonist pro-drug mimics the beneficial effects of physical exercise on neurogenesis, behavior, and exercise-related molecular pathways in an Alzheimer’s disease mouse model (2022) (0)
- Designing Robust N-of-1 Studies for Precision Medicine: Simulation Study and Design Recommendations (Preprint) (2018) (0)
- SINGLE NUCLEI AND SINGLE WHOLE CELL SEQUENCING OF ALZHEIMER’S DISEASE (2019) (0)
- Patient-Specific Mutation-Derived Tumor Antigens As Targets for Cancer Immunotherapy in Multiple Myeloma (2015) (0)
- Adaptive landscape of protein variation in human (2018) (0)
- Abstract B230: Targeting mitochondria for metastatic lung adenocarcinoma specific lethality. (2013) (0)
- DEVELOPMENT OF A FULLY AUTOMATED PROCESSING CARTRIDGE FOR THE STR-TYPING OF SEXUAL ASSAULT SAMPLES (2006) (0)
- Building a Secure Biomedical Data Sharing Decentralized App (DApp): Tutorial (Preprint) (2019) (0)
- Abstract B023: Identification and biochemical validation of piperlongumine as a potent therapeutic against neuroendocrine prostate cancer (2018) (0)
- How Mount Sinai Health System Fosters Collaboration to Fight Cancer (2018) (0)
- Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans (2019) (0)
- 707 PI3-Kinase inhibitors represent a novel class of drug repurposing candidates to prevent/alleviate glucocorticoid-induced skin atrophy (2017) (0)
- The promise of genomics-based drug repurposing. (2014) (0)
- Identifying Acute Low Back Pain Episodes in Primary Care Practice From Clinical Notes: Observational Study (Preprint) (2019) (0)
- Supplemental Information Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells (2016) (0)
- Identifying Acute Low Back Pain Episodes in Primary Care Practice from Clinical Notes (2019) (0)
- 727 Use of PI3K/mTOR/Akt inhibitors as skin protectors to spare skin from glucocorticoid-induced atrophy (2019) (0)
- The Evolution of Mining Electronic Health Records in the Era of Deep Learning (2022) (0)
- Systematic Analysis of Environmental Chemicals That Dysregulate Critical Period Plasticity-Related Gene Expression Reveals Common Pathways That Mimic Immune Response to Pathogen (2020) (0)
- INVESTIGATION OF NOVEL DRUG TARGETS IMPLICATED IN HIGH-DOSE STATIN THERAPY FROM YELLOW-II TRIAL: TOWARDS PERSONALIZED LIPID LOWERING THERAPIES (2017) (0)
- Intracoronary Imaging, Cholesterol Efflux, and Transcriptomics after Intensive Statin Treatment in Diabetes (2017) (0)
- Abstract 3250: Computational drug repositioning and biochemical validation of piperlongumine as a potent therapeutic agent for neuroendocrine prostate cancer (2017) (0)
- A gentle introduction to genomics (2013) (0)
- ADAR1 Drives Disease Progression in Multiple Myeloma By Acting Both As an RNA Editor of Specific Transcripts and As a DNA Mutator of Their Cognate Genes (2019) (0)
- Geospatial Resolution of H uman and Bacterial Diversity with City-Scale Metagenomics Graphical Abstract Highlights (2015) (0)
- Abstract 131: Network-driven Drug Repositioning Unveils a New Anti-atherosclerotic Effect of an Old Compound (2020) (0)
- 345: Novel insights on molecular targets of environmental exposures during pregnancy using placental multiomics integration (2015) (0)
- Identification of serum protein biomarkers for small cell lung cancer. (2011) (0)
- Building a Secure Biomedical Data Sharing Decentralized App: Tutorial (2019) (0)
- Using integrative informatics to bridge toxicogenomics and disease biology (2013) (0)
- Practical and ethical considerations in personal genomics (2013) (0)
- ATHEROSCLEROTIC PLAQUE MORPHOLOGY IN RESPONSE TO HIGH INTENSITY LIPID LOWERING THERAPY BY MULTIMODALITY IMAGING AMONG WOMEN AND MEN: A YELLOW-II SUB-STUDY (2017) (0)
- Information extraction from clinical notes: A systematic review for Chronic Diseases (Preprint) (2018) (0)
- Aberrant a-to-I RNA Editing and Prognostic Impact of Adar in Multiple Myeloma Patients with 1q Amplification (2016) (0)
- Towards a Network-Based Molecular Taxonomy of Newly Diagnosed Multiple Myeloma (2015) (0)
- Big data, predictive modeling and data science in precision medicine (2016) (0)
- From DNA to physiology (2013) (0)
- Abstract 3772: A multi-scale survey to assess the impact of inflammatory diseases of the abdominal cavity and prostate cancer severity (2017) (0)
- Ancestry and Genealogy (2013) (0)
- FRI-246-Elimination of HCV in a Large Urban Health System in the United States: A Big-data Approach (2019) (0)
- SUN-253 Effects of Growth Hormone Stimulation on the Immunologic Cellular Landscape in Pediatric Patients (2019) (0)
- Better healthcare delivery using big data analytics and machine learning (2016) (0)
- Privacy-Preserving Methods for Feature Engineering Using Blockchain: Review, Evaluation, and Proof of Concept (Preprint) (2019) (0)
- Expression quantitative trait loci in placenta tissues from the national children’s study reveal developmental origins of human complex diseases (2014) (0)
- CL-01 Translation of Clinical Proteomics : Opportunities and Challenges (2013) (0)
- Repurposing the atypical antidepressant trazodone for atherosclerotic cardiovascular disease (2021) (0)
- Chapter 1 – Systems Immunology (2016) (0)
- EHDviz: Open source framework for building real-time biomedical and healthcare data visualizations and dashboards (2016) (0)
- 158. Decoding Brain Epigenome Maps with Broad Histone H3K4me3 Domains: Discovering Functional Epigenetic Patterns and Their Dynamics in Gene Regulatory Networks (2017) (0)
- A MULTISCALE SURVEY OF INFLAMMATORY DISEASES AND PROSTATE ONCOPHENOTYPES.: MP14‐08 (2017) (0)
- Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma (2017) (0)
- Using SNOMED CT For Translational Genomics Data Integration (2008) (0)
- Abstract 1027: Regulatory T-cell genes drive altered immune microenvironment in adult solid cancers and allow for immune contextual patient subtyping (2018) (0)
- 103 Computational Prediction and Experimental Validation of FABP-1 as a Putative Biomarker for Pancreatic Adenocarcinoma: A Novel Approach to Biomarker Discovery for Gastrointestinal Disorders (2010) (0)
- Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits (2019) (0)
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