Johannes Roth
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Computer Science
Johannes Roth's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Johannes Roth's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock (2007) (1272)
- Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein (2008) (884)
- S100 proteins expressed in phagocytes: a novel group of damage‐associated molecular pattern molecules (2007) (817)
- The endogenous Toll–like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer (2009) (719)
- Myeloid-related Protein (MRP) 8 and MRP14, Calcium-binding Proteins of the S100 Family, Are Secreted by Activated Monocytes via a Novel, Tubulin-dependent Pathway* (1997) (560)
- Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel (2010) (521)
- Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils (2010) (427)
- Alarmins: awaiting a clinical response. (2012) (413)
- Phagocyte-specific S100 proteins: a novel group of proinflammatory molecules. (2003) (408)
- Myeloid-related proteins 8 and 14 are specifically secreted during interaction of phagocytes and activated endothelium and are useful markers for monitoring disease activity in pauciarticular-onset juvenile rheumatoid arthritis. (2000) (396)
- Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes. (2007) (390)
- Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection (2011) (379)
- Mechanisms of Disease: a 'DAMP' view of inflammatory arthritis (2007) (356)
- S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity (2003) (354)
- Proinflammatory S100 proteins in arthritis and autoimmune disease. (2004) (339)
- Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis. (2004) (327)
- Loss of S100A9 (MRP14) Results in Reduced Interleukin-8-Induced CD11b Surface Expression, a Polarized Microfilament System, and Diminished Responsiveness to Chemoattractants In Vitro (2003) (320)
- Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation. (2004) (319)
- MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes. (2004) (318)
- Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells. (2005) (307)
- Identification of Human S100A9 as a Novel Target for Treatment of Autoimmune Disease via Binding to Quinoline-3-Carboxamides (2009) (297)
- Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut. (2012) (283)
- The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells (2010) (278)
- Influenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression (2008) (271)
- Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis (2005) (264)
- Calcium-dependent complex assembly of the myeloic differentiation proteins MRP-8 and MRP-14. (1991) (245)
- Staphylococcus aureus small-colony variants are adapted phenotypes for intracellular persistence. (2010) (241)
- Expression of the pro-inflammatory protein S100A12 (EN-RAGE) in rheumatoid and psoriatic arthritis. (2003) (232)
- S100A8/A9: From basic science to clinical application. (2016) (227)
- The Ca2+-binding Proteins S100A8 and S100A9 Are Encoded by Novel Injury-regulated Genes* (2001) (223)
- Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain. (1992) (219)
- Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial. (2010) (211)
- S100A12 Is Expressed Exclusively by Granulocytes and Acts Independently from MRP8 and MRP14* (1999) (210)
- The calcium‐binding proteins MRP8 and MRP14 form a membrane‐associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions (1992) (199)
- Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis (2007) (190)
- S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown origin. (2008) (186)
- Active involvement of alarmins S100A8 and S100A9 in the regulation of synovial activation and joint destruction during mouse and human osteoarthritis. (2012) (186)
- S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis. (2013) (178)
- The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1beta form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis. (2009) (177)
- Myeloid-Derived Suppressor Cells Regulate Growth of Multiple Myeloma by Inhibiting T Cells in Bone Marrow (2013) (177)
- Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4. (2012) (169)
- Glucocorticoids induce an activated, anti‐inflammatory monocyte subset in mice that resembles myeloid‐derived suppressor cells (2008) (165)
- Biophysical characterization of S100A8 and S100A9 in the absence and presence of bivalent cations. (2006) (161)
- Calcium-dependent tetramer formation of S100A8 and S100A9 is essential for biological activity. (2006) (159)
- Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations. (2004) (159)
- Phagocyte‐specific S100 proteins are released from affected mucosa and promote immune responses during inflammatory bowel disease (2008) (157)
- Elevated serum levels of calcium‐binding S100 proteins A8 and A9 reflect disease activity and abnormal differentiation of keratinocytes in psoriasis (2006) (147)
- MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program. (2007) (145)
- Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity (2014) (144)
- Staphylococcus aureus Panton‐Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome (2012) (138)
- Erk5 Activation Elicits a Vasoprotective Endothelial Phenotype via Induction of Krüppel-like Factor 4 (KLF4)* (2010) (136)
- Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis (2012) (136)
- Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18 (2012) (135)
- S100A12 (EN-RAGE) in monitoring Kawasaki disease (2003) (135)
- MRP8 and MRP14, S-100-like proteins associated with myeloid differentiation, are translocated to plasma membrane and intermediate filaments in a calcium-dependent manner (1993) (134)
- The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis (2012) (134)
- Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1β, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: rationale for combination treatment during arthritis. (2011) (133)
- Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritis. (2003) (132)
- S100A9 Interaction with TLR4 Promotes Tumor Growth (2012) (131)
- Nickel chloride and cobalt chloride, two common contact sensitizers, directly induce expression of intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and endothelial leukocyte adhesion molecule (ELAM-1) by endothelial cells. (1993) (129)
- Proinflammatory S100A12 can activate human monocytes via Toll-like receptor 4. (2013) (128)
- Increased perivascular synovial membrane expression of myeloid-related proteins in psoriatic arthritis. (2003) (128)
- Transcriptional profiling of IKK2/NF-κB— and p38 MAP kinasedependent gene expression in TNF-α—stimulated primary human endothelial cells (2004) (128)
- Calcium-induced noncovalently linked tetramers of MRP8 and MRP14 detected by ultraviolet matrix-assisted laser desorption/ionization mass spectrometry (1999) (127)
- Serum cytochrome c indicates in vivo apoptosis and can serve as a prognostic marker during cancer therapy (2005) (126)
- Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation (2018) (126)
- Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion (2015) (126)
- Activation of nuclear factor-kappa B and gene expression in human endothelial cells by the common haptens nickel and cobalt. (1995) (124)
- Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome (2007) (123)
- TNF induces distinct gene expression programs in microvascular and macrovascular human endothelial cells (2006) (123)
- MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis. (2015) (123)
- MRP8 and MRP14, S-100-like proteins associated with myeloid differentiation, are translocated to plasma membrane and intermediate filaments in a calcium-dependent manner. (1993) (123)
- Differential expression and response to anti‐TNFα treatment of infiltrating versus resident tissue macrophage subsets in autoimmune arthritis (2005) (121)
- Generation of a novel therapeutic peptide that depletes MDSC in tumor-bearing mice (2013) (120)
- Insulin or a closely related molecule is native to Escherichia coli. (1981) (119)
- Induction of nuclear factor‐κB responses by the S100A9 protein is Toll‐like receptor‐4‐dependent (2012) (118)
- Hyperzincaemia and hypercalprotectinaemia: a new disorder of zinc metabolism (2002) (118)
- Expression and role of myeloid-related protein-14 in clinical and experimental sepsis. (2009) (117)
- Sodium chloride promotes pro-inflammatory macrophage polarization thereby aggravating CNS autoimmunity. (2016) (115)
- Farber disease: clinical presentation, pathogenesis and a new approach to treatment (2007) (115)
- The binding of thyroxine by serum albumin as measured by fluorescence quenching. (1966) (115)
- Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study (2012) (110)
- Complex pattern of the myelo-monocytic differentiation antigens MRP8 and MRP14 during chronic airway inflammation. (1992) (109)
- Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases. (2019) (105)
- Phagocyte-specific S100A8/A9 Protein Levels During Disease Exacerbations and Infections in Systemic Lupus Erythematosus (2009) (104)
- S100-alarmin-induced innate immune programming protects newborn infants from sepsis (2017) (103)
- Calcium-induced noncovalently linked tetramers of MRP8 and MRP14 are confirmed by electrospray ionization-mass analysis (2000) (101)
- Early recruitment of phagocytes contributes to the vascular inflammation of giant cell arteritis (2004) (101)
- Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells. (2004) (97)
- Peroxisome Proliferator-Activated Receptor-γ Modulates the Response of Macrophages to Lipopolysaccharide and Glucocorticoids (2018) (94)
- More Than Suppression: Glucocorticoid Action on Monocytes and Macrophages (2019) (93)
- Essential Impact of NF-κB Signaling on the H5N1 Influenza A Virus-Induced Transcriptome1 (2009) (93)
- Inhibition of p38 Mitogen-activated Protein Kinase Impairs Influenza Virus-induced Primary and Secondary Host Gene Responses and Protects Mice from Lethal H5N1 Infection* (2013) (92)
- Expression and complex formation of S100-like proteins MRP8 and MRP14 by macrophages during renal allograft rejection. (1994) (91)
- Vitamin D receptor signaling contributes to susceptibility to infection with Leishmania major (2007) (91)
- Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis. (2008) (91)
- Methotrexate treatment in juvenile idiopathic arthritis: when is the right time to stop? (2004) (86)
- Analysis of the MRP8-MRP14 Protein-Protein Interaction by the Two-hybrid System Suggests a Prominent Role of the C-terminal Domain of S100 Proteins in Dimer Formation* (1999) (86)
- Increase of calcium levels in epithelial cells induces translocation of calcium-binding proteins migration inhibitory factor-related protein 8 (MRP8) and MRP14 to keratin intermediate filaments. (1995) (86)
- Expression of Toll-Like Receptors in Neonatal Sepsis (2005) (85)
- Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3. (2010) (85)
- Cellular events associated with inflammatory angiogenesis in the mouse cornea. (1991) (84)
- Elevated calprotectin levels reveal bowel inflammation in spondyloarthritis (2015) (84)
- S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll-like receptor 4: implications for bone destruction in murine antigen-induced arthritis. (2011) (83)
- Partial purification and characterization of an insulin-like material from spinach and Lemna gibba G3. (1987) (83)
- A subgroup of juvenile idiopathic arthritis patients who respond well to methotrexate are identified by the serum biomarker MRP8/14 protein. (2013) (82)
- Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions. (2014) (82)
- Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects (2019) (81)
- Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases. (2015) (81)
- In Vivo Optical Imaging of Cellular Inflammatory Response in Granuloma Formation Using Fluorescence-Labeled Macrophages (2009) (81)
- Expression of calcium-binding proteins MRP8 and MRP14 in inflammatory muscle diseases. (2003) (80)
- Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils (2020) (79)
- S100 proteins in rheumatic diseases (2018) (79)
- Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment (2017) (79)
- S100A8 and S100A9 in experimental osteoarthritis (2010) (78)
- Neutrophil-derived S100A12 as novel biomarker of inflammation in familial Mediterranean fever (2009) (78)
- Coordinate expression of activating Fc gamma receptors I and III and inhibiting Fc gamma receptor type II in the determination of joint inflammation and cartilage destruction during immune complex-mediated arthritis. (2003) (77)
- Expression of MRP8 and MRP14 by macrophages is a marker for severe forms of glomerulonephritis (2004) (75)
- Treatment efficacy of adipose-derived stem cells in experimental osteoarthritis is driven by high synovial activation and reflected by S100A8/A9 serum levels. (2014) (74)
- Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12. (2007) (73)
- The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF-κB and Hypoxia-Inducible Factor-1α1 (2007) (72)
- Alarmins S100A8/S100A9 aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis (2014) (71)
- Keratinocytes Determine Th1 Immunity during Early Experimental Leishmaniasis (2010) (71)
- Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis (2015) (71)
- Proteomic analysis of plasma identifies the Toll-like receptor agonists S100A8/A9 as a novel possible marker for systemic sclerosis phenotype (2014) (70)
- Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity (2018) (69)
- Early activation of cutaneous vessels and epithelial cells is characteristic of acute systemic onset juvenile idiopathic arthritis (2005) (69)
- Blockade of Myeloid-Derived Suppressor Cell Expansion with All-Trans Retinoic Acid Increases the Efficacy of Antiangiogenic Therapy. (2018) (68)
- LFA-1 contributes to signal I of T-cell activation and to the production of T(h)1 cytokines. (2010) (68)
- Transcriptome Assessment Reveals a Dominant Role for TLR4 in the Activation of Human Monocytes by the Alarmin MRP8 (2015) (68)
- Elevated S100A8/A9 and S100A12 Serum Levels Reflect Intraocular Inflammation in Juvenile Idiopathic Arthritis-Associated Uveitis: Results From a Pilot Study. (2015) (67)
- Neutrophil-derived S100A12 is profoundly upregulated in the early stage of acute Kawasaki disease. (2004) (66)
- Expression of myeloid-related protein-8 and -14 in patients with acute Kawasaki disease. (2006) (66)
- Expression and complex assembly of calcium‐binding proteins MRP8 and MRP14 during differentiation of murine myelomonocytic cells (1993) (65)
- The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes. (2003) (65)
- Candida albicans Triggers Activation of Distinct Signaling Pathways to Establish a Proinflammatory Gene Expression Program in Primary Human Endothelial Cells1 (2007) (65)
- Expression of surfactant protein-C, S100A8, S100A9, and B cell markers in renal allografts: investigation of the prognostic value. (2005) (64)
- Reprogramming of Monocytes by GM-CSF Contributes to Regulatory Immune Functions during Intestinal Inflammation (2015) (63)
- Soluble CD163 promotes recognition, phagocytosis and killing of Staphylococcus aureus via binding of specific fibronectin peptides (2012) (63)
- Different pathways leading to cutaneous leukocytoclastic vasculitis in mice (2001) (63)
- Myeloid related protein 8 and 14 secretion reflects phagocyte activation and correlates with disease activity in juvenile idiopathic arthritis treated with autologous stem cell transplantation (2003) (61)
- MRP8/14 serum levels as a predictor of response to starting and stopping anti-TNF treatment in juvenile idiopathic arthritis (2015) (61)
- Alarming consequences – autoinflammatory disease spectrum due to mutations in proline-serine-threonine phosphatase-interacting protein 1 (2016) (60)
- Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis (2007) (59)
- The Transcriptional Repressor cAMP Response Element Modulator α Interacts with Histone Deacetylase 1 to Repress Promoter Activity1 (2006) (59)
- Mrp14 Deficiency Ameliorates Amyloid β Burden by Increasing Microglial Phagocytosis and Modulation of Amyloid Precursor Protein Processing (2012) (59)
- MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes (2011) (59)
- Staphylococcal strains vary greatly in their ability to induce an inflammatory response in endothelial cells. (2010) (59)
- Cerebral Arterial Stenoses and Stroke: Novel Features of Aicardi-Goutières Syndrome Caused by the Arg164X Mutation in SAMHD1 Are Associated with Altered Cytokine Expression (2010) (57)
- Myeloid related proteins MRP8/MRP14 may predict disease flares in juvenile idiopathic arthritis. (2004) (57)
- The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis (2012) (55)
- Identification of a novel surface molecule, RM3/1, that contributes to the adhesion of glucocorticoid‐induced human monocytes to endothelial cells (1996) (55)
- The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion. (2015) (55)
- Myeloid‐Related Proteins 8 and 14 Contribute to Monosodium Urate Monohydrate Crystal–Induced Inflammation in Gout (2014) (55)
- Expression of calcium-binding proteins MRP8 and MRP14 is associated with distinct monocytic differentiation pathways in HL-60 cells. (1993) (55)
- H5N1 Virus Activates Signaling Pathways in Human Endothelial Cells Resulting in a Specific Imbalanced Inflammatory Response (2011) (55)
- Pervasive head-to-tail insertions of DNA templates mask desired CRISPR/Cas9-mediated genome editing events (2019) (54)
- Expression of the calcium-binding proteins MRP8 and MRP14 in monocytes is regulated by a calcium-induced suppressor mechanism. (1994) (52)
- Alarmin S100A9 Induces Proinflammatory and Catabolic Effects Predominantly in the M1 Macrophages of Human Osteoarthritic Synovium (2016) (52)
- High LDL levels lead to increased synovial inflammation and accelerated ectopic bone formation during experimental osteoarthritis. (2016) (52)
- The role of ceramide in receptor- and stress-induced apoptosis studied in acidic ceramidase-deficient Farber disease cells (2001) (50)
- Subcutaneous infection with S. aureus in mice reveals association of resistance with influx of neutrophils and Th2 response. (2011) (48)
- Validation of Relapse Risk Biomarkers for Routine Use in Patients With Juvenile Idiopathic Arthritis (2014) (48)
- Highly pathogenic avian influenza viruses inhibit effective immune responses of human blood‐derived macrophages (2012) (48)
- The Cyclic AMP Response Element Modulator Regulates Transcription of the TCR ζ-Chain1 (2005) (47)
- E‐SELECTIN EXPRESSION IN EXPERIMENTAL MODELS OF INFLAMMATION IN MICE (1996) (46)
- Gout Is a Chronic Inflammatory Disease in Which High Levels of Interleukin‐8 (CXCL8), Myeloid‐Related Protein 8/Myeloid‐Related Protein 14 Complex, and an Altered Proteome Are Associated With Diabetes Mellitus and Cardiovascular Disease (2015) (46)
- Interaction between S100A8/A9 and Annexin A6 Is Involved in the Calcium-induced Cell Surface Exposition of S100A8/A9* (2008) (45)
- Interleukin-1 is not involved in synovial inflammation and cartilage destruction in collagenase-induced osteoarthritis. (2017) (45)
- Among the S100 proteins, S100A12 is the most significant marker for psoriasis disease activity (2016) (45)
- S100A8 causes a shift toward expression of activatory Fcγ receptors on macrophages via toll-like receptor 4 and regulates Fcγ receptor expression in synovium during chronic experimental arthritis. (2010) (44)
- Immunohistochemical detection of bFGF and TNF-alpha in the course of inflammatory angiogenesis in the mouse cornea. (1990) (43)
- Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation (2018) (42)
- The monoclonal antibody MAC387 detects an epitope on the calcium‐binding protein MRP14 (1994) (42)
- Expression of the calcium-binding proteins MRP8 and MRP14 by early infiltrating cells in experimental contact dermatitis. (1992) (42)
- S100A8 and S100A9 are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants. (2020) (41)
- Focal loss of CD44 variant protein expression is related to recurrence in superficial bladder carcinoma. (1999) (41)
- Glucosidase II, a protein of the endoplasmic reticulum with high mannose oligosaccharide chains and a rapid turnover. (1987) (41)
- Alarmins of the S100-Family in Juvenile Autoimmune and Auto-Inflammatory Diseases (2019) (40)
- Myeloid related protein induces muscle derived inflammatory mediators in juvenile dermatomyositis (2013) (39)
- High Levels of S100A8/A9 Proteins Aggravate Ventilator-Induced Lung Injury via TLR4 Signaling (2013) (38)
- Binding of Two Nuclear Complexes to a Novel Regulatory Element within the Human S100A9 Promoter Drives the S100A9 Gene Expression* (2002) (38)
- Nrf2 Is a Central Regulator of Metabolic Reprogramming of Myeloid-Derived Suppressor Cells in Steady State and Sepsis (2018) (38)
- S100-alarmins: potential therapeutic targets for arthritis (2017) (37)
- Molecular basis of the complex formation between the two calcium-binding proteins S100A8 (MRP8) and S100A9 (MRP14) (2005) (37)
- Pervasive head-to-tail insertions of DNA templates mask desired CRISPR-Cas9–mediated genome editing events (2020) (36)
- Alarmin S100A8 Activates Alveolar Epithelial Cells in the Context of Acute Lung Injury in a TLR4-Dependent Manner (2017) (34)
- Translational research network and patient registry for auto-inflammatory diseases. (2011) (34)
- In neonates S100A8/S100A9 alarmins prevent the expansion of a specific inflammatory monocyte population promoting septic shock (2017) (34)
- Impaired cellular energy metabolism in cord blood macrophages contributes to abortive response toward inflammatory threats (2019) (34)
- Myeloid-related protein-8/14 facilitates bacterial growth during pneumococcal pneumonia (2014) (34)
- Homocysteine inhibits tumor necrosis factor-induced activation of endothelium via modulation of nuclear factor-kappa b activity. (2001) (33)
- Expression of intercellular adhesion molecule-1 in murine allergic contact dermatitis. (1990) (33)
- Myeloid marker S100A8/A9 and lymphocyte marker, soluble interleukin 2 receptor: biomarkers of hidradenitis suppurativa disease activity? (2013) (33)
- Substance P and calcitonin gene-related peptide modulate leukocyte infiltration to mouse skin during allergic contact dermatitis (2004) (32)
- Synovial macrophages promote TGF-β signaling and protect against influx of S100A8/S100A9-producing cells after intra-articular injections of oxidized low-density lipoproteins. (2016) (32)
- Induction of an anti-inflammatory human monocyte subtype is a unique property of glucocorticoids, but can be modified by IL-6 and IL-10. (2012) (32)
- Site of blood vessel damage and relevance of CD18 in a murine model of immune complex-mediated vasculitis. (2007) (32)
- Epidermal expression of the calcium binding surface antigen 27E10 in inflammatory skin diseases (2004) (32)
- Harnessing the Maltodextrin Transport Mechanism for Targeted Bacterial Imaging: Structural Requirements for Improved in vivo Stability in Tracer Design (2018) (31)
- Signaling mechanisms inducing hypo-responsiveness of phagocytes during systemic inflammation. (2019) (31)
- Immune Suppression via Glucocorticoid-Stimulated Monocytes: A Novel Mechanism To Cope with Inflammation (2014) (31)
- Myeloid-related protein 14 promotes inflammation and injury in meningitis. (2015) (30)
- S100A12 and Soluble Receptor for Advanced Glycation End Products Levels During Human Severe Sepsis (2013) (30)
- Expression and Function of S100A8/A9 (Calprotectin) in Human Typhoid Fever and the Murine Salmonella Model (2015) (29)
- Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils (2019) (29)
- Reversal of Sepsis‐Like Features of Neutrophils by Interleukin‐1 Blockade in Patients With Systemic‐Onset Juvenile Idiopathic Arthritis (2018) (29)
- Optical In Vivo Imaging of the Alarmin S100A9 in Tumor Lesions Allows for Estimation of the Individual Malignant Potential by Evaluation of Tumor–Host Cell Interaction (2015) (28)
- Treatment ef fi cacy of adipose-derived stem cells in experimental osteoarthritis is driven by high synovial activation and re fl ected by S 100 A 8 / A 9 serum levels (27)
- S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis (2017) (27)
- The Absence of Cutaneous Lymph Nodes Results in a Th2 Response and Increased Susceptibility to Leishmania major Infection in Mice (2008) (26)
- S100A8/A9 Is Not Involved in Host Defense against Murine Urinary Tract Infection (2010) (26)
- The Cyclic AMP Response Element Modulator α Suppresses CD86 Expression and APC Function1 (2009) (25)
- A Novel Intronic cAMP Response Element Modulator (CREM) Promoter Is Regulated by Activator Protein-1 (AP-1) and Accounts for Altered Activation-induced CREM Expression in T Cells from Patients with Systemic Lupus Erythematosus* (2011) (25)
- A Personalized Approach to Biological Therapy Using Prediction of Clinical Response Based on MRP8/14 Serum Complex Levels in Rheumatoid Arthritis Patients (2016) (24)
- From Synovial Tissue to Peripheral Blood: Myeloid Related Protein 8/14 Is a Sensitive Biomarker for Effective Treatment in Early Drug Development in Patients with Rheumatoid Arthritis (2014) (22)
- High expression of myeloid‐related proteins 8 and 14 characterizes an inflammatorily active but ineffective response of macrophages during leprosy (2004) (22)
- Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium (2018) (22)
- Imaging, myeloid precursor immortalization, and genome editing for defining mechanisms of leukocyte recruitment in vivo (2018) (21)
- Overexpression of CREMα in T Cells Aggravates Lipopolysaccharide-Induced Acute Lung Injury (2013) (21)
- Oncolytic influenza virus infection restores immunocompetence of lung tumor-associated alveolar macrophages (2018) (21)
- High Amounts of S100-Alarmins Confer Antimicrobial Activity on Human Breast Milk Targeting Pathogens Relevant in Neonatal Sepsis (2017) (21)
- Chemotactic activity of S100A8 and S100A9. (2003) (21)
- The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion (2016) (21)
- CD163 expression defines specific, IRF8-dependent, immune-modulatory macrophages in the bone marrow. (2020) (21)
- In Vivo Imaging of Pro- and Antitumoral Cellular Components of the Tumor Microenvironment (2017) (20)
- Purification and characterization of two lectins from Caragana arborescens seeds. (1976) (20)
- Doxycycline-Induced Expression of Transgenic Human Tumor Necrosis Factor α in Adult Mice Results in Psoriasis-like Arthritis (2013) (20)
- Ultrastructural localization of the S-100-like proteins MRP8 and MRP14 in monocytes is calcium-dependent (1994) (19)
- Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis (2020) (19)
- Interleukin 17 Promotes Expression of Alarmins S100A8 and S100A9 During the Inflammatory Response of Keratinocytes (2021) (19)
- S100A8/A9, a potent serum and molecular imaging biomarker for synovial inflammation and joint destruction in seronegative experimental arthritis (2016) (19)
- Myeloid-related protein-14 deficiency promotes inflammation in staphylococcal pneumonia (2015) (19)
- Impact of carbon ion irradiation on epidermal growth factor receptor signaling and glioma cell migration in comparison to conventional photon irradiation (2013) (19)
- The 5A apolipoprotein A‐I (apoA‐I) mimetic peptide ameliorates experimental colitis by regulating monocyte infiltration (2016) (18)
- S100A8 and S100A9 Calcium-Binding Proteins: Localization Within Normal and Cyclosporin A-Induced Overgrowth Gingiva (2002) (18)
- Beneficial Immune Effects of Myeloid‐Related Proteins in Kidney Transplant Rejection (2016) (18)
- Differences in migration inhibitory factor production by C57Bl/6 and BALB/c mice in allergic and irritant contact dermatitis. (1990) (17)
- IL-1β-Mediated Activation of Adipose-Derived Mesenchymal Stromal Cells Results in PMN Reallocation and Enhanced Phagocytosis: A Possible Mechanism for the Reduction of Osteoarthritis Pathology (2019) (16)
- Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target. (2015) (16)
- Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing (2017) (15)
- Awareness of Fabry disease among rheumatologists—current status and perspectives (2011) (15)
- The cAMP response element modulator (CREM) regulates TH2 mediated inflammation (2015) (15)
- Use of nonspecific cleavage products for protein sequence analysis as shown on calcyclin isolated from human granulocytes (2001) (15)
- Genetic modification of ER‐Hoxb8 osteoclast precursors using CRISPR/Cas9 as a novel way to allow studies on osteoclast biology (2017) (14)
- S 100 A 9 Interaction with TLR 4 Promotes Tumor Growth (2012) (14)
- The role of NOX2-derived reactive oxygen species in collagenase-induced osteoarthritis. (2018) (14)
- Determination of the peptide binding motif and high-affinity ligands for HLA-DQ4 using synthetic peptide libraries. (2004) (12)
- Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis (2018) (12)
- Role of proteinase‐activated receptor‐2 in anti‐bacterial and immunomodulatory effects of interferon‐γ on human neutrophils and monocytes (2011) (12)
- pp75: A novel tyrosine-phosphorylated protein that heralds differentiation of HL-60 cells. (1991) (12)
- Importance of superoxide dismutases A and M for protection of Staphylococcus aureus in the oxidative stressful environment of cystic fibrosis airways (2020) (12)
- Circulating calprotectin (S100A8/A9) is higher in rheumatoid arthritis patients that relapse within 12 months of tapering anti-rheumatic drugs (2019) (12)
- Increased Levels of S100A8/A9 in Patients with Peritonsillar Abscess: A New Promising Diagnostic Marker to Differentiate between Peritonsillar Abscess and Peritonsillitis (2017) (11)
- Association between serum levels of the proinflammatory protein S100A8/A9 and clinical and structural characteristics of patients with established knee, hip, and hand osteoarthritis (2015) (11)
- Potentials and pitfalls of DNA array analysis of the endothelial stress response. (2005) (11)
- The contact allergens nickel chloride and cobalt chloride directly induce expression of endothelial adhesion molecules. (1993) (11)
- Scavenger receptor class A type I/II determines matrix metalloproteinase-mediated cartilage destruction and chondrocyte death in antigen-induced arthritis. (2009) (11)
- Endothelial cells present an innate resistance to glucocorticoid treatment: implications for therapy of primary vasculitis (2011) (10)
- Epidermal expression of I‐TAC (Cxc111) instructs adaptive Th2‐type immunity (2014) (10)
- K2P18.1 translates T cell receptor signals into thymic regulatory T cell development (2021) (10)
- Highly Pathogenic Influenza Viruses Inhibit Inflammatory Response in Monocytes via Activation of Rar-Related Orphan Receptor RORa (2013) (9)
- Inhibition of p 38 mitogen-activated protein kinase impairs influenza virus-induced primary and secondary host gene responses and protects mice from lethal H 5 N 1 infection (2017) (9)
- Endothelial Basement Membrane Laminins as an Environmental Cue in Monocyte Differentiation to Macrophages (2020) (8)
- The alarmin S100A9 hampers osteoclast differentiation from human circulating precursors by reducing the expression of RANK (2019) (8)
- Association of Diverse Staphylococcus aureus Populations with Pseudomonas aeruginosa Coinfection and Inflammation in Cystic Fibrosis Airway Infection (2021) (8)
- Expression of murine VCAM-1 in vitro and in different models of inflammation in vivo: correlation with immigration of monocytes. (1995) (8)
- S100A8/A9 is the first predictive marker for neonatal sepsis (2021) (7)
- Activation‐dependent cell death of human monocytes is a novel mechanism of fine‐tuning inflammation and autoimmunity (2016) (6)
- Active involvement of alarmins S100A8 and S100A9 in regulation of synovial activation and joint destruction during osteoarthrit (2010) (6)
- Soluble CD163 masks fibronectin‐binding protein A‐mediated inflammatory activation of Staphylococcus aureus infected monocytes (2014) (6)
- Real-time methods for spectral functions (2021) (6)
- Nox2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis (2021) (6)
- Transcriptional profiling of IKK 2 / NF-B – and p 38 MAP kinase – dependent gene expression in TNF-– stimulated primary human endothelial cells (2004) (5)
- S100 Proteins in Monitoring Inflammation: The Importance of a Gold Standard and a Validated Methodology (2005) (5)
- The Good and the Bad: Monocytes’ and Macrophages’ Diverse Functions in Inflammation (2022) (5)
- MRP8/14 serum levels as diagnostic markers for systemic juvenile idiopathic arthritis in children with prolonged fever. (2021) (5)
- Systemic Activation of Neutrophils by Immune Complexes Is Critical to IgA Vasculitis (2022) (5)
- The severity of irritant contact dermatitis in various strains of mice correlates with endothelial expression of migration inhibitory factor (MIF) (2005) (5)
- A novel mutatioin in the PSTPIP1 gene is associated with an autoinflammatory disease distinct from classical PAPA syndrome (2011) (5)
- PAPA Syndrome and the Spectrum of PSTPIP1-Associated Inflammatory Diseases (2019) (4)
- A Non-Peptidic S100A9 Specific Ligand for Optical Imaging of Phagocyte Activity In Vivo (2018) (4)
- OP0146 Alarmins S100a8/S100a9 Aggravate Osteophyte Formation in Experimental Osteoarthritis and PREDICT Osteophyte Progression in Early Human Osteoarthritis in the Dutch CHECK Cohort (2014) (4)
- Alarmins S100A8/A9 cause osteophyte formation in experimental osteoarthritis with high synovial involvement (2013) (4)
- A single dose of anti-IL-1β antibodies prevents Western diet-induced immune activation during early stage collagenase-induced osteoarthritis, but does not ameliorate end-stage pathology. (2021) (3)
- Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two (2017) (3)
- Potential of the Novel PTA Score to Identify Patients with Peritonsillar Inflammation Profiting from Medical Treatment (2018) (3)
- Alarming and Calming: Opposing Roles of S100A8/S100A9 Dimers and Tetramers on Monocytes (2022) (3)
- Human S100A8 and S100A9 activate phagocytes via Toll-like receptor 4 independent of RAGE (2009) (3)
- Analysis of monocyte cell tractions in 2.5D reveals mesoscale mechanics of podosomes during substrate-indenting cell protrusion (2022) (3)
- Aryl Hydrocarbon Receptor-Signaling Regulates Early Leishmania major-Induced Cytokine Expression (2019) (3)
- The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis (2020) (3)
- C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9 (2021) (3)
- Target-Specific Imaging of Cathepsin and S100A8/A9 Reflects Specific Features of Malignancy and Enables Estimation of Tumor Malignancy (2020) (3)
- Proteomic analysis of Systemic Sclerosis serum identifies the toll-like receptor agonists S100A8/A9 as a novel possible pathogenic marker (2010) (3)
- Elevation of inflammatory S100A8/S100A9 complexes in intracranial aneurysms (2020) (3)
- 2.5D Tractions in monocytes reveal mesoscale mechanics of podosomes during substrate indenting cell protrusion (2021) (2)
- OP0099 Toll-like receptor 4 agonists MRP 8 and MRP 14 act as endogenous enhancers of MSU-crystal induced IL-1 secretion in vitro and reflect disease activity in gout patients in vivo (2013) (2)
- THU0167 MRP8/14 Serum Complexes as Predictor of Response to Biological Treatments in Rheumatoid Arthritis (2013) (2)
- A8.1 Alarmins S100A8/A9 Cause Osteophyte Formation in Experimental Osteoarthritis with High Synovial Involvement (2013) (2)
- SAT0006 High Systemic LDL Cholesterol Levels Lead to Synovial Activation and Strongly Accelerate Development of Ectopic Bone Formation During Experimental Osteoarthritis (2015) (2)
- Alarmins S100A8 and S100A9 stimulate production of pro-inflammatory cytokines in M2 macrophages without changing their M2 membrane phenotype (2012) (2)
- Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis (2022) (2)
- Immune Resolution Dilemma: Host Antimicrobial Factor S100A8/A9 Modulates Inflammatory Collateral Tissue Damage During Disseminated Fungal Peritonitis (2021) (2)
- Critical dynamics in a real-time formulation of the functional renormalization group (2023) (2)
- OR6-004 – MRP8/14 promote MSU-crystal induced inflammation (2013) (2)
- Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells (2022) (1)
- S100A9-Imaging Enables Estimation of Early Therapy-Mediated Changes in the Inflammatory Tumor Microenvironment (2021) (1)
- PW02-018 - Impact of PSTPIP1 mutaions on clinical phenotype (2013) (1)
- A153: Long‐term Outcomes of Childhood‐Onset Systemic Lupus Erythematosus in Adulthood (2014) (1)
- A1.30 A key role of S100A9 in the pathogenesis of psoriatic arthritis in TTP/S100 deficient mice (2016) (1)
- Author Correction: Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing (2018) (1)
- 094 ACTIVE INVOLVEMENT OF “ALARMINS” S100A8 AND A9 IN REGULATION OF SYNOVIAL ACTIVATION AND JOINT DESTRUCTION DURING OSTEOARTHRITIS (2009) (1)
- PW03-031 – Activation-induced cell death of human monocytes (2013) (1)
- S100A8/A9 modulates inflammatory collateral tissue damage during intraperitoneal origin systemic candidiasis (2020) (1)
- Alarmins S100A8/S100A9 stimulate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in the check cohort of early human osteoarthritis patients (2014) (1)
- S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo (2022) (1)
- Biallelic TLR4 deficiency in humans. (2022) (1)
- PReS-FINAL-2068: S100 A8/A9 serum levels reflect disease activity in juvenile idiopathic arthritis-associated uveitis (2013) (1)
- Spontaneous onset of TNFα‐triggered colonic inflammation depends on functional T lymphocytes, S100A8/A9 alarmins, and MHC H‐2 haplotype (2020) (1)
- S100A8 and S100A9 induce a catabolic shift in chondrocytes from human osteoarthritis patients (2011) (1)
- S100A8/A9 is not essential for the development of inflammation and joint pathology in interleukin-1 receptor antagonist knockout mice (2021) (1)
- Role of S100A8/A9 in Platelet–Neutrophil Complex Formation during Acute Inflammation (2022) (1)
- THU0067 NLRP3 inflammasome activity in monocytes is regulated by 12/15-lipoxygenase (2017) (1)
- S100A8/S100A9 Integrates F-Actin and Microtubule Dynamics to Prevent Uncontrolled Extravasation of Leukocytes (2023) (1)
- Calgranulin levels are elevated in spondyloarthritis and reflect the presence of acute microscopic gut inflammation (2014) (1)
- Rapid Communication Immunohistochemical Detection of bFGF and TNF-a in the Course of Inflammatory Angiogenesis in the Mouse Cornea (2007) (1)
- The Damage Associated Molecular Pattern (DAMP) molecule S100A12 induces pro-inflammatory responses in monocytes via innate immunity signalling pathways (2008) (1)
- Elevated serum levels of alarmin S100A8/A9 in patients with hand osteoarthritis. (2019) (1)
- The endogenous TLR-4 ligands MRP8/14 as biomarkers of inflammation in Familial Mediterranean Fever (FMF) (2008) (1)
- The alarmins high mobility group box protein 1 and S100A8/A9 display different inflammatory profiles after acute knee injury. (2022) (1)
- Alarmins S100A8 AND S100A9 skew chondrocytes towards a cartilage breakdown phenotype (2010) (1)
- High systemic LDL cholesterol levels during experimental osteoarthritis lead to increased synovial activation and ectopic bone formation at end-stage osteoarthritis, while excessive levels accelerate development of joint pathology already at early-stage of osteoarthritis (2015) (1)
- IL-1 blockade as a novel approach to treatment of hyperzincemia and hypercalprotectinemia, a possible new autoinflammatory syndrome (2012) (1)
- Crosslinking of microtubules and actin filaments by S100A8/S100A9 (2009) (1)
- PReS-FINAL-2340: A pathogenic role for S100A8/A9 in experimental autoimmune arthritis (2013) (0)
- A9.10 Synovial activation drives anti-inflammatory effects of adipose-derived stem cells after local administration in experimental oa which is reflected by s100a8/a9 levels in the serum (2014) (0)
- OP0299 Synovial Activation in Experimental OA Drives Rapid Suppressive Effects of Adipose-Derived Stem Cells after Local Administration and Protects Against Development of Ligament Damage (2013) (0)
- OP0320 S100a9 hampers osteoclast differentiation from circulating precursors by reducing the expression of rank (2018) (0)
- 01.03 Ttp/s100a9 deficient mice promote a tnf-dependent psoriatic arthritis phenotype triggered by the bacterial environment (2017) (0)
- Evaluation of the QUANTUM BLUE sCAL rapid test as a point of care tool to identify patients with peritonsillar abscess (2021) (0)
- Specific Imbalanced Inflammatory Response Human Endothelial Cells Resulting in a H5N1 Virus Activates Signaling Pathways in (2010) (0)
- Myeloid cells which secrete S100 proteins in juvenile dermatomyositis may contribute to disease activity (2008) (0)
- Use of Non-Specific Cleavage in Protein Digests for Modification Analysis (2001) (0)
- 226 ALARMINS S100A8 AND S100A9 SKEW CHONDROCYTES TOWARDS A CARTILAGE BREAKDOWN PHENOTYPE IN HUMAN OSTEOARTHRITIS (2010) (0)
- S100-Alarmins are Crucial Host Factors for the Postnatal Development of Gut Homeostasis (2019) (0)
- SAT0010 The damp protein S100A8/A9 is crucially involved in myeloid-derived suppressor cell (MDSC) differentiation and function in collagen-induced arthritis (2017) (0)
- Interactions between S100A8 and DDR2 mechanisms in cartilage degradation in osteoarthritis (2013) (0)
- in Primary Human Endothelial Cells Proinflammatory Gene Expression Program Distinct Signaling Pathways to Establish a Triggers Activation of Candida albicans (2007) (0)
- IL-8 and IFN-γ as Preoperative Predictors of the Outcome of Tonsillectomy (2020) (0)
- Impaired cellular energy metabolism in cord blood macrophages contributes to abortive response toward inflammatory threats (2019) (0)
- Increased levels of S100A8/A9, IL-1ß and IL-18 as a novel biomarker for recurrent tonsillitis (2021) (0)
- AB0038 S100A8/9 ASSOCIATES WITH PAIN PERCEPTION IN OA PATIENTS AND INDUCES NOCICEPTIVE PAIN BUT NOT ALLODYNIA IN EXPERIMENTAL SYNOVITIS (2019) (0)
- [Leukocytoclastic vasculitis]. (2004) (0)
- Infections in Systemic Lupus Erythematosus Phagocyte-specific S 100 A 8 / A 9 Protein Levels During Disease Exacerbations (2009) (0)
- ‘Alarmins’ S100A8 and A9 are actively involved in regulation of synovial activation and joint destruction during mouse and human osteoarthritis (2012) (0)
- Endothelial cell activation and mononuclear cell infiltration during allergic and irritant contact dermatitis (1992) (0)
- A1.09 S100-damps in IL-1RA-/- mice, a serum biomarker and in vivo imaging tool to assess joint inflammation and destruction in experimental seronegative arthritis (2016) (0)
- SP0013 S100-alarmins: potential therapeutic targets for arthritis (2018) (0)
- Synovial macrophages promote TGF-β signaling after intra-articular injections of oxidized LDL in naïve murine knee joints, preventing production of pro-inflammatory factors S100A8/9, chemokines and aggrecanase-induced neo-epitopes (2015) (0)
- Increased levels of S100A8/A9, IL-1ß and IL-18 as a novel biomarker for recurrent tonsillitis (2021) (0)
- Calcium binding proteins S 100 A 8 / A 9 affect macrophage polarization and deteriorate repair-phase following renal ischemia / reperfusion (2012) (0)
- Trapping endothelial-specific genes (2004) (0)
- S100A8 enhances osteoclast-mediated bone resorption in experimental antigen-induced arthritis through activation of toll-like receptor 4 (2011) (0)
- Infection in Mice Leishmania major Susceptibility to Results in a Th2 Response and Increased The Absence of Cutaneous Lymph Nodes (2014) (0)
- Cells in Bone Marrow Growth of Multiple Myeloma by Inhibiting T Myeloid-Derived Suppressor Cells Regulate (2013) (0)
- 251 ALARMINS S100A8 AND S100A9 ELICIT AN ENHANCED CATABOLIC RESPONSE IN CHONDROCYTES FROM OSTEOARTHRITIS PATIENTS THAT IS TOLL LIKE RECEPTOR 4 DEPENDENT (2011) (0)
- A1.14 Synovial macrophages promote TGF-β signalling but protect against influx of S100A8/S100A9-producing cells after intra-articular injections of oxidised low-density lipoproteins (2016) (0)
- OP0305 THE ALARMIN S100A9 HAMPERS OSTEOCLAST DIFFERENTIATION FROM CIRCULATING PRECURSORS BY REDUCING THE EXPRESSION OF RANK (2019) (0)
- ‘Alarmins’ S100A8 and A9 determine synovial activation and joint destruction during experimental osteoarthritis (2011) (0)
- Functional characterization of GM-CSF induced monocyte subsets (2008) (0)
- FRI0039 Synovial Macrophages Promote TGF-Beta Signaling but Protect against Influx of S100a8/s100a9-Producing Cells Following Intra-Articular Injections of Oxidized Low-Density Lipoproteins (2016) (0)
- OP0091 S100a8 triggers a novel immune-regulatory mechanism in developing dendritic cells (2017) (0)
- The anti-inflammatory stage of monocytes after long-term stimulation with LPS is mediated by p38 MAP kinase dependent epigenetic silencing (2008) (0)
- The roles of toll-like receptor 4, CD33, CD68, CD69, or CD147/EMMPRIN for monocyte activation by the DAMP S100A8/S100A9 (2023) (0)
- 092 “ALARMINS” S100A8 AND A9 ARE ACTIVELY INVOLVED IN REGULATION OF CARTILAGE DESTRUCTION DURING OSTEOARTHRITIS (2010) (0)
- ammation in staphylococcal pneumonia (2015) (0)
- during Intestinal Inflammation Functions Contributes to Regulatory Immune Reprogramming of Monocytes by GM-CSF (2015) (0)
- The phagocyte specific protein S100A12 as a novel biomarker in Muckle-Wells-Syndrome before and during therapy with Anakinra and Canakinumab (ACZ885) (2008) (0)
- PReS-FINAL-2145: MRP8/14 serum complexes as predictor of response to etanercept treatment in juvenile idiopathic arthritis (2013) (0)
- Elevated LDL cholesterol-levels during experimental OA leads to increased synovial thickening , s100a8/9 production and ectopic bone formation (2014) (0)
- Associations of Betatrophin/ANGPTL8 with Septic Dyslipidemia in Human Peritonitis: An Explorative Analysis (2022) (0)
- UVA1 radiation attenuates pro‐inflammatory functions in human monocytes (2022) (0)
- S100A8/A9 in bleomycin-induced skin fibrosis (2011) (0)
- Complex regulation of alarmins S100A8/A9 and secretion via Gasdermin-D pores exacerbates autoinflammation in Familial Mediterranean Fever. (2023) (0)
- Front Cover: Harnessing the Maltodextrin Transport Mechanism for Targeted Bacterial Imaging: Structural Requirements for Improved in vivo Stability in Tracer Design (ChemMedChem 3/2018) (2018) (0)
- transendothelial migration of phagocytes MRP8 and MRP14 control microtubule reorganization during (2013) (0)
- Patients with SARS-CoV-2-Induced Viral Sepsis Simultaneously Show Immune Activation, Impaired Immune Function and a Procoagulatory Disease State (2023) (0)
- PReS-FINAL-2332: Activation-induced cell death of human monocytes as a novel mechanism fine-tuning inflammation and autoimmunity (2013) (0)
- A10.19 MRP8/14 Serum Complexes as Predictor of Response to Biological Treatments in Rheumatoid Arthritis (2013) (0)
- The TLR4 ligands MRP8 and MRP14 in the diagnosis and pathogenesis of systemic onset juvenile idiopathic arthritis (2008) (0)
- Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing (2017) (0)
- OP0249 The Alarmins S100A8/A9 Induce Canonical WNT Signaling in Naïve Mouse Knee Joints and Experimental OA (2015) (0)
- P074 The alarmin S100A9 hampers osteoclast differentiation from circulating precursors by reducing the expression of rank (2019) (0)
- Recovery of S100A8 in the absence of S100A9 exacerbates TNFα-mediated psoriatic-like arthritis (IRC4P.462) (2015) (0)
- Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils (2019) (0)
- A9.13 systemic LDL cholesterol-accumulation during experimental oa leads to increased synovial thickening, s100a8/9 production and ectopic bone formation (2014) (0)
- OR6-001 - S100A12 as pro-inflammatory TLR4 ligand (2013) (0)
- P001 ASSOCIATION OF CHRONIC OLIGOARTHRITIS WITH HLA CLASS II ALLELES: DRB1, DQB1 AND DQA1 IN BULGARIAN CHILDREN BY AUTOLOGOUS STEM CELL TRANSPLANTATION (ASCT) IN PATIENTS WITH (JIA) (2001) (0)
- Development and evaluation of new small molecule PET-radiotracers for the molecular imaging of inflammatory processes targeting S100A9 (2022) (0)
- 40 THE “ALARMIN” S100 A8: AN ACTIVATOR OF CHONDROCYTE MEDIATED CARTILAGE DAMAGE? (2007) (0)
- Abstract 3648: S100A9 play a role in MDSC expansion and migration but not in their activation (2011) (0)
- The nuclear receptor NR4A1 restrains neutrophil granulocyte mediated brain damage in cerebral ischemia (2022) (0)
- Synovial Tissue Biology 812 ELEVATED LDL CHOLESTEROL-LEVELS DURING EXPERIMENTAL OA LEADS TO INCREASED SYNOVIAL THICKENING , S 100 A 8 / 9 PRODUCTION AND ECTOPIC BONE FORMATION (2014) (0)
- P102 S100A9 hampers osteoclast differentiation from circulating precursors by reducing the expression of rank (2018) (0)
- Synovial activation drives anit-inflammatory effects of adipose-derived stem cells after local administration in experimental OA which is reflected by s100a8/a9 levels in the serum (2014) (0)
- A5.11 alarmins S100A8/S100A9 stimulate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human osteoarthritis (2014) (0)
- 228 P38 AND MEK/ERK MAP KINASES REGULATE COMMON AND UNIQUE GENE SETS IN CHONDROCYTES (2010) (0)
- OP0152 Synovial Macrophages Promote TGF-β Signaling After Intra-Articular Injections of Oxidized LDL in Naïve Murine Knee Joints, Preventing Production of Pro-Inflammatory Factors S100A8/9, Chemokines and Aggrecanase-Induced Neo-Epitopes (2015) (0)
- Abstract 5399: S100A9 drives MDSC migration and contributes to tumor progression by inhibiting the immune response (2012) (0)
- Monitoring local inflammation in JIA (2014) (0)
- OP0024 Synovial Activation Drives Efficacy of Anti-Inflammatory Effects of Adipose-Derived Stem Cells in Experimental OA Which is Reflected by Serum Levels of S100a8/A9 (2014) (0)
- 9.1 Innate resistance of endothelial cells to the effects of glucocorticoids (2008) (0)
- SAT0022 S100a8/a9 Is A Potent Serum and Imaging Biomarker Tool for Assessing Joint Inflammation and Destruction in Seronegative Experimental Arthritis (2016) (0)
- A4.1 Synovial macrophages promote TGF-β signalling after intra-articular injections of oxidised LDL in naÏve murine knee joints, preventing production of pro-inflammatory factors S100A8/9, chemokines and aggrecanase-induced neo-epitopes (2015) (0)
- SAT0324 The Association between the Proinflammatory Protein S100A8/A9 with Clinical Data and Structural Abnormalities in Patients with Established Knee, Hip and Hand Osteoarthritis (2013) (0)
- THU0554 12/15-Lipoxygenase Counteracts the Activity of NLRP3 Inflammasome in Monocytes (2014) (0)
- Abstract 2445: Dynamic Change and Pivotal Role of Myeloid-Related Protein (MRP) 8 and MRP14 in Acute Kawasaki Disease (2006) (0)
- SAT0656 Optical imaging of phagocyte migration represents a novel method to determine disease activity in cia (2017) (0)
- MRP8/14 is a Protective Mediator in Murine Klebsiella (K.) Pneumoniae Induced Pneumonia - (2012) (0)
- A5.13 Serum levels of S100A8/A9 complex and corticosterone correlate to synovial inflammation and cartilage/bone damage in IL-1RA-/-MICE, a model system for seronegative arthritis (2014) (0)
- Alarmin S100A8 causes severe cartilage damage in antigen-induced arthritis through TLR4 activation and upregulation of FcεRI and FcεRIV (2010) (0)
- SAT0248 Calgranulins are Elevated in Spondyloarthritis and Reflect the Presence of Acute Microscopic Bowel Inflammation (2015) (0)
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What Schools Are Affiliated With Johannes Roth?
Johannes Roth is affiliated with the following schools:
