John Allen Clements
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American professor in pulmonary biology
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John Allen Clements's Degrees
- Masters Computer Science Stanford University
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Why Is John Allen Clements Influential?
(Suggest an Edit or Addition)According to Wikipedia, John Allen Clements is a physician known for his role in the study of pulmonary surfactant. He graduated from Weill Cornell Medical College in 1947. He is a professor at University of California, San Francisco.
John Allen Clements's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Processing of tumour necrosis factor-α precursor by metalloproteinases (1994) (904)
- Isolation of disaturated phosphatidylcholine with osmium tetroxide. (1976) (689)
- The TIMP2 Membrane Type 1 Metalloproteinase “Receptor” Regulates the Concentration and Efficient Activation of Progelatinase A (1998) (627)
- Surface Tension of Lung Extracts (1957) (528)
- Surface active materials from dog lung. II. Composition and physiological correlations. (1972) (499)
- Processing of tumour necrosis factor-alpha precursor by metalloproteinases. (1994) (430)
- Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D. (1998) (417)
- Metabolism and turnover of lung surfactant. (1987) (405)
- Kinetics of acetaminophen absorption and gastric emptying in man (1978) (366)
- Nucleotide and amino acid sequences of pulmonary surfactant protein SP 18 and evidence for cooperation between SP 18 and SP 28-36 in surfactant lipid adsorption. (1987) (338)
- Assessment of the risk of the respiratory-distress syndrome by a rapid test for surfactant in amniotic fluid. (1972) (334)
- Pulmonary surface tension and alveolar stability. (1961) (322)
- Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lung. (1995) (292)
- Composition of surface-active material isolated from beef lung. (1961) (292)
- Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview (1997) (286)
- Surfactant apoprotein Mr = 26,000-36,000 enhances uptake of liposomes by type II cells. (1987) (280)
- NEONATAL PULMONARY ISCHEMIA Part I: Clinical and Physiological Studies (1967) (279)
- Pulmonary surface tension and the mucus lining of the lungs: some theoretical considerations. (1958) (249)
- Subfractionation of lung surfactant. Implications for metabolism and surface activity. (1983) (234)
- Isolation of apoproteins from canine surface active material. (1973) (226)
- Inhibition of matrix metalloproteinases and tumour necrosis factor alpha converting enzyme as adjuvant therapy in pneumococcal meningitis. (2001) (223)
- Alveolar Epithelial Cell Mitochondria as Source of the Surface-Active Lung Lining (1962) (220)
- Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-α inhibitor (1997) (215)
- Antibiotic Activity and Characterization of BB-3497, a Novel Peptide Deformylase Inhibitor (2001) (204)
- Direct determination of surface tension in the lung. (1976) (197)
- Pulmonary surfactant therapy. (1995) (197)
- Matrix metalloproteinase expression in an experimentally-induced DTH model of multiple sclerosis in the rat CNS (1998) (192)
- Pulmonary surfactant and its apoproteins. (1990) (192)
- Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 Å resolution (1995) (189)
- Ontogeny of tracheal fluid, pulmonary surfactant, and plasma corticoids in the fetal lamb. (1975) (189)
- Enhanced expression of MMP-7 and MMP-9 in demyelinating multiple sclerosis lesions (1997) (185)
- Surface active materials from dog lung. I. Method of isolation. (1972) (177)
- Matrix metalloproteinase-9 and -7 are regulated in experimental autoimmune encephalomyelitis. (1998) (173)
- Pulmonary surface film stability and composition. (1979) (163)
- Antibacterial Activities and Characterization of Novel Inhibitors of LpxC (2002) (159)
- Pulmonary surface tension. (1959) (156)
- Stromelysin-1 (Matrix Metalloproteinase-3) and Tissue Inhibitor of Metalloproteinase-3 Are Overexpressed in the Wall of Abdominal Aortic Aneurysms (2002) (150)
- Control of lung surfactant by ventilation, adrenergic mediators, and prostaglandins in the rabbit. (2015) (150)
- Low molecular weight human pulmonary surfactant protein (SP5): isolation, characterization, and cDNA and amino acid sequences. (1987) (149)
- Lung surfactant and neonatal respiratory distress syndrome. (1998) (147)
- Surfactant release in excised rat lung is stimulated by air inflation. (1981) (143)
- Ventilatory and cholinergic control of pulmonary surfactant in the rabbit. (1977) (139)
- Integrin alpha 4 beta 1-mediated melanoma cell adhesion and migration on vascular cell adhesion molecule-1 (VCAM-1) and the alternatively spliced IIICS region of fibronectin. (1994) (137)
- Identification of MMP-18, a putative novel human matrix metalloproteinase. (1996) (135)
- Alveolar subphase pH in the lungs of anesthetized rabbits. (1981) (133)
- PRELIMINARY REPORT. THE PULMONARY HYPOPERFUSION SYNDROME. (1965) (133)
- Structure of canine pulmonary surfactant apoprotein: cDNA and complete amino acid sequence. (1985) (132)
- Tracheal fluid in fetal lambs: spontaneous decrease prior to birth. (1979) (130)
- Functions of the alveolar lining. (2015) (129)
- Pulmonary Surfactant and Evolution of the Lungs (1970) (127)
- Rates of replacement of lecithins and alveolar instability in rat lungs. (1967) (122)
- Macrophage-inflammatory protein protects multipotent hematopoietic cells from the cytotoxic effects of hydroxyurea in vivo. (1992) (120)
- Direct determination of volume- and time-dependence of alveolar surface tension in excised lungs. (1978) (116)
- Identification of a key integrin-binding sequence in VCAM-1 homologous to the LDV active site in fibronectin. (1994) (115)
- Surfactant in the lung and tracheal fluid of the fetal lamb and acceleration of its appearance by dexamethasone. (1975) (106)
- Initial clinical trial of EXOSURF, a protein-free synthetic surfactant, for the prophylaxis and early treatment of hyaline membrane disease. (1991) (103)
- Precursor-product relationship between rabbit type II cell lamellar bodies and alveolar surface-active material. Surfactant turnover time. (1981) (103)
- Differential expression of matrix metalloproteinases in bacterial meningitis. (1999) (102)
- Expression of specific matrix metalloproteinases in inflammatory myopathies. (2001) (101)
- Interferon-beta inhibits activated leukocyte migration through human brain microvascular endothelial cell monolayer. (1999) (98)
- Pulmonary edema and permeability of alveolar membranes. (1961) (96)
- Surfactant Apoprotein A Modifies the Inhibitory Effect of Plasma Proteins on Surfactant Activity In Vivo (1995) (95)
- Effects of a protein-free, synthetic surfactant on survival and pulmonary function in preterm lambs. (1985) (95)
- Competitive binding of vascular cell adhesion molecule-1 and the HepII/IIICS domain of fibronectin to the integrin alpha 4 beta 1. (1994) (92)
- Nonionic polymers reverse inactivation of surfactant by meconium and other substances. (1999) (91)
- Comparison of captive and pulsating bubble surfactometers with use of lung surfactants. (1994) (89)
- Protein composition of rabbit alveolar surfactant subfractions. (1984) (89)
- Surface active materials from dog lung. 3. Thermal analysis. (1972) (89)
- Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors (1998) (87)
- Matrix metalloproteinase expression during experimental autoimmune neuritis. (1998) (87)
- Distinct binding specificities of integrins α4β7 (LPAM-1), α4β1 (VLA-4), and αIELβ7 (1994) (86)
- Lung surfactant proteins, SP-B and SP-C, alter the thermodynamic properties of phospholipid membranes: a differential calorimetry study. (1993) (86)
- Head-tilt method of oral resuscitation. (1960) (86)
- Phosphatidylglycerol-deficient lung surfactant has normal properties. (1983) (82)
- Lung function in prematurely delivered rabbits treated with a synthetic surfactant. (1987) (80)
- Pulmonary and Circulatory Effects of Fibrinopeptides (1967) (80)
- Prepartum maturation of the lung in fetal sheep: relation to cortisol. (1981) (80)
- Quantitation of matrix metalloproteinases in cultured rat astrocytes using the polymerase chain reaction with a multi‐competitor cDNA standard (1996) (78)
- Efficiency of translation initiation by non-AUG codons in Saccharomyces cerevisiae (1988) (77)
- Lung surfactant: a personal perspective. (1997) (76)
- Ventilation enhances pulmonary alveolar clearance of radioactive dipalmitoyl phosphatidylcholine in liposomes. (1980) (75)
- Mechanism of compliance change in excised rat lungs at low transpulmonary pressure. (1970) (72)
- Lung volume in the newborn infant. (1962) (72)
- Oxygen and carbon dioxide exchange and energy cost of expired air resuscitation. (1958) (72)
- Polymer-surfactant treatment of meconium-induced acute lung injury. (2000) (71)
- Neonatal pulmonary ischemia. I. Clinical and physiological studies. (1967) (70)
- Uptake of lung surfactant subfractions into lamellar bodies of adult rabbit lungs. (1986) (69)
- Surface activity of rabbit pulmonary surfactant subfractions at different concentrations in a captive bubble. (1994) (68)
- PULMONARY SURFACE TENSION IN EXPERIMENTAL ATELECTASIS. (1964) (68)
- The radioimmunoassay of pulmonary surface active material in sheep lung. (2015) (67)
- Isolation and properties of type II alveolar cells from rat lung. (1977) (62)
- NEONATAL PULMONARY ISCHEMIA (1967) (61)
- mRNA sequences influencing translation and the selection of AUG initiator codons in the yeast Saccharomyces cerevisiae (1996) (60)
- Transcription and processing signals in the 3-phosphoglycerate kinase (PGK) gene from Aspergillus nidulans. (1986) (60)
- Evaluation of pressure-driven captive bubble surfactometer. (1994) (59)
- Cellular uptake and processing of surfactant lipids and apoprotein SP-A by rat lung. (1989) (58)
- Studies of the structure of lung surfactant protein SP-A. (1989) (58)
- Pulmonary surface tension and alveolar stability. (1961) (57)
- Association between receptor density, cellular activation, and transformation of adhesive behavior of flowing lymphocytes binding to VCAM‐1 (1997) (57)
- Estimation of pulmonary resistance by repetitive interruption of airflow. (1959) (57)
- In vitro antibacterial activity of the peptide deformylase inhibitor BB-83698. (2004) (55)
- Hyaluronan Decreases Surfactant Inactivation In Vitro (2005) (55)
- Stimulation of breathing movements in fetal sheep by inhibitors of prostaglandin synthesis. (1979) (54)
- Secretion of human epidermal growth factor from Saccharomyces cerevisiae using synthetic leader sequences. (1991) (54)
- Pharmacokinetics in Animals and Humans of a First-in-Class Peptide Deformylase Inhibitor (2004) (52)
- Hyaluronan Reduces Surfactant Inhibition and Improves Rat Lung Function after Meconium Injury (2005) (51)
- Biological and structural properties of MIP-1 alpha expressed in yeast. (1992) (50)
- Two PDGF‐B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activation. (1991) (50)
- Comparative lipid chemistry of lungs. (1971) (47)
- Polyethylene glycol/surfactant mixtures improve lung function after HCl and endotoxin lung injuries. (2001) (47)
- Surface tension in the lungs. (1962) (46)
- Effective treatment of models of multiple sclerosis with matrix metalloproteinase inhibitors (1998) (46)
- Activation dependent and independent VLA-4 binding sites on vascular cell adhesion molecule-1. (1994) (45)
- Changes in phospholipid composition of lung surfactant during development in the fetal lamb. (1983) (45)
- Correlation of Mechanical Properties of Infant Lungs with Surface Activity of Extracts.∗ (1962) (41)
- Coagulation-dependent mechanisms and asthma. (2004) (40)
- Changes in quantity, composition, and surface activity of alveolar surfactant at birth. (1987) (39)
- Sequence analysis and transformation by the catabolic 3-dehydroquinase (QUTE) gene from Aspergillus nidulans. (1986) (35)
- Surface phenomena in relation to pulmonary function. (1962) (35)
- Acetaminophen absorption and metabolism in celiac disease and Crohn's disease (1981) (35)
- Dispersal of Rabbit Lung into Individual Viable Cells: A New Model for the Study of Lung Metabolism (1972) (33)
- SURFACTANT IN PULMONARY DISEASE. (1965) (33)
- Synthesis and expression of genes encoding tuna, pigeon, and horse cytochromes c in the yeast Saccharomyces cerevisiae. (1991) (33)
- Prolonged transgene expression in rodent lung cells. (1992) (32)
- Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain. (2003) (31)
- Isolation and identification of type 2 alveolar epithelial cells. (1975) (30)
- Reduction of excitotoxicity and associated leukocyte recruitment by a broad‐spectrum matrix metalloproteinase inhibitor (2004) (29)
- Pulmonary maturation in the hypophysectomised ovine fetus. Differential responses to adrenocorticotrophin and cortisol. (1981) (29)
- Novel approaches to antimicrobial therapy: peptide deformylase. (2002) (28)
- Alveolar Surface Tension and Lung Surfactant (2011) (28)
- Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group. (2002) (28)
- Peptide Deformylase Inhibitors, Potential for a New Class of Broad Spectrum Antibacterials (2002) (27)
- Lung function, surfactant apoprotein content, and level of PEEP in prematurely delivered rabbits. (1994) (26)
- Inhibitors of prostaglandin synthesis, tracheal fluid, and surfactant in fetal lambs. (1981) (26)
- Effect of lung collapse on alveolar surfactant in rabbits subjected to unilateral pneumothorax. (1989) (26)
- Distinct binding specificities of integrins alpha 4 beta 7 (LPAM-1), alpha 4 beta 1 (VLA-4), and alpha IEL beta 7. (1994) (24)
- Cloning and characterization of a gene encoding pig epidermal growth factor. (1991) (23)
- Structure--activity relationships of the peptide deformylase inhibitor BB-3497: modification of the P2' and P3' side chains. (2003) (23)
- Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor. (2004) (21)
- Uptake of pulmonary surfactant protein C into adult rat lung lamellar bodies. (1993) (20)
- Surfactant secretion and clearance in the newborn. (1989) (19)
- Separation by gel chromatography of naturally occurring phosphatidylcholine mixtures according to number of ethylenic linkages. (1970) (19)
- Expression and activity of a gene encoding rat cytochrome c in the yeast Saccharomyces cerevisiae. (1989) (19)
- Radioimmunoassay of pulmonary surface-active material in the tracheal fluid of the fetal lamb. (2015) (18)
- Polyethylene Glycol-Surfactant for Lavage Lung Injury in Rats (2005) (18)
- Smoking and pulmonary surfactant. (1972) (17)
- Peptide deformylase inhibitors with activity against respiratory tract pathogens. (2004) (17)
- Molecular cloning of the 3-phosphoglycerate kinase (PGK) gene from Aspergillus nidulans (2004) (16)
- Antenatal prediction of graduated risk of hyaline membrane disease by amniotic fluid foam test for surfactant. (1979) (15)
- NO2 interfacial transfer is reduced by phospholipid monolayers. (2001) (14)
- Secretion and Clearance of Lung Surfactant: A Brief Review1 (1981) (14)
- Urinary levels of substance P and its metabolites are not increased in interstitial cystitis (2001) (14)
- An uncommon phosphatidylcholine specific for surface-active material in canine lung. (1973) (12)
- Polyethylene Glycol (PEG) Results in Concentration-Dependent Sedimentation of Survanta and Improvement of Its Function (1999) (12)
- Association of surfactant protein C with isolated alveolar type II cells. (1995) (10)
- The Role of Messenger RNA Sequences and Structures in Eukaryotic Translation (1987) (10)
- Generation of Human Umbilical Vein Endothelial Cell Lines Which Maintain Their Differentiated Phenotype (1994) (10)
- Expression of active horseradish peroxidase in Saccharomyces cerevisiae. (1992) (10)
- Amino acid residues required for binding of vascular cell adhesion molecule-1 to integrin alpha 4 beta 7. (1997) (9)
- Crystallization and preliminary X-ray diffraction characterisation of both a native and selenomethionyl VLA-4 binding fragment of VCAM-1. (1994) (9)
- Transfer of phospholipids by a protein fraction obtained from canine pulmonary lavage. (1988) (9)
- Lipid Synthesis and Surfactant Turnover in the Lungs (1985) (9)
- Hyaluronan with dextran added to therapeutic lung surfactants improves effectiveness in vitro and in vivo (2013) (9)
- Isolation and Properties of Type II Alveolar Cells from Rat Lung1, 2 (2015) (8)
- ESTIMATION OF PULMONARY RESISTANCE BY REPETITIVE INTERRUPTION OF AIRFLOW (1961) (8)
- Turnover of Lung Surfactant1 (1984) (8)
- Determination of isoprenaline by ion-pair high-pressure liquid chromatography (1980) (7)
- The role of yeast mRNA sequences and structures in translation. (1989) (7)
- Matrix Metalloproteinases Exhibit Different Expression Patterns in Inflammatory Demyelinating Diseases of the Central and Peripheral Nervous System (1999) (7)
- Acute effects of pulmonary artery occlusion on the pool of alveolar surfactant. (1981) (6)
- Lung Surface Tension and Surfactant: The Early Years (1996) (5)
- Exogenous surfactant for human lung disease. Current status. (1983) (5)
- PRELIMINARY REPORT (1965) (4)
- Artificial respiration for the nerve gas casualty. (1956) (4)
- Characterization of the structure and conformation of platelet-derived growth factor-BB (PDGF-BB) and proteinase-resistant mutants of PDGF-BB expressed in Saccharomyces cerevisiae. (1992) (3)
- A pressure plethysmograph with a pneumatic differentiator for pulmonary capillary flow measurements. (1969) (3)
- The Alveolar Lining Layer (2008) (3)
- Matrix metalloproteinase expression in a rat model of experimental autoimmune neuritis (1997) (2)
- Some Relationships Among Structure, Composition, and Functional Characteristics of Lung Surfactant (1987) (2)
- ONTOGENY OF TRACHEAL FLUID, PULMONARY SURFACTANT AND PLASMA CORTISOL IN THE FETAL LAMB (1974) (2)
- Surfactant protein group with molecular weights 28,000 to 36,000 daltons (SP 28-36) increases the association of phospholipids with freshly isolated type II cells (1986) (2)
- Polyethylene Glycol (PEG) Enhances Surfactant Treatment of Acute Lung Injury from Meconium (1999) (2)
- Biochemical aspects of pulmonary function. Introductory remarks. (1974) (1)
- Expression and characterisation of a very-late antigen-4 (alpha 4 beta 1) integrin-binding fragment of vascular cell-adhesion molecule-1. (1994) (1)
- CONTROLLED TRIAL OF A PROTEIN-FREE SYNTHETIC SURFACTANT IN PRETERM RABBITS (1984) (1)
- Lung surfactant: an alternate hypothesis. (1971) (1)
- Hydroxamic acid derivatives as antibacterial drug (1999) (1)
- Structural Features of mRNA that Affect Translation in Yeast (1988) (1)
- Pulmonary surfactant: an engineering marvel (1999) (1)
- Amino acid residues required for binding of vascular cell adhesion molecule-1 to integrin α 4 β 7 (1997) (0)
- COMPARISON OF THE PHARMACOKINETICS OF INTRAVENOUS AND ORAL PROPRANOLOL IN OBESE AND NORMAL VOLUNTEERS (1985) (0)
- Intraalveolar Metabolism of Lung Surfactant (1990) (0)
- 1188 INTERCOSTAL RETRACTOMETER FOR ESTIMATION OF INTRA-PLEURAL PRESSURE (1978) (0)
- The influence of surface tension kinetics on lung pressure volume relations (1990) (0)
- Molecular characterization of the 3-phosphoglycerate kinase gene from Aspergillus nidulans. (1986) (0)
- An intercostal retractometer for estimation of intrapleural pressure changes in infants. (1982) (0)
- Study Of The Effects Of Tube Size, Food Supply, And Volume Of Medium On The Autogamy Rate Of Paramecium Aurelia, Variety I, Strain 51.7 K (1952) (0)
- PULMONARY AND CARDIOVASCULAR EFFECTS OF A TOTALLY SYNTHETIC, PROTEINFREE SURFACTANT IN PRETERM LAMBS (1984) (0)
- Enhanced expression of matrilysin and 92 kDa gelatinase in demyelinating multiple sclerosis lesions (1997) (0)
- Nucleotide and amino acid sequences of pulmonary surfactant protein SE 18 and evidence for cooperation between SP 18 and SP 28-36 in surfactant lipid adsorption (lung/lipid-protein interactions/proteolipid) (2016) (0)
- The Interrelationships of Pulmonary Surface Tension, Ventilation, and Circulation. (1962) (0)
- Lung Surfactant: Its Contribution to Lung Distensibility (1973) (0)
- Surfactant Kinetics in the Newborn Rabbit (1990) (0)
- Activation State of Α4β1 Integrin Controls Capture, Immobilization and Migration of Flowing Lymphocytes on Purified VCAM-1 (1998) (0)
- Synthetic metalloproteinase inhibitors block the processing of Pro-TNFα in vitro and in vivo (1994) (0)
- Separation by gel chromatography of naturally incorporates suitable precursors into a lecithin fraction occurring phosphatidylcholine mixtures according to number of ethylenic linkages (2002) (0)
- Different expression patterns of matrix metalloproteinases in inflammatory demyelinating diseases of the central and peripheral nervous system (1998) (0)
- Lung surfactant: present status and future prospects. (1973) (0)
- CRYSTAL STRUCTURE OF E.COLI POLYPEPTIDE DEFORMYLASE COMPLEXED WITH THE INHIBITOR BB-3497 (2001) (0)
- 1367 PRECURSOR-PRODUCT(PP) RELATIONSHIP BETWEEN RABBIT TYPE II CELL LAMELLAR BODIES(LB) AND ALVEOLAR SURFACE ACTIVE MATERIAL(SAM) AND SAM TURNOVER TIME (1981) (0)
- THE CRYSTAL STRUCTURE OF E.COLI PEPTIDE DEFORMYLASE COMPLEXED WITH ACTINONIN (2001) (0)
- Letters to the Editor (1965) (0)
- F127. Vascular cell adhesion molecule (VCAM-1) can mediate rolling and stationary adhesion of flowing lymphocytes (1995) (0)
- Pulmonary surfactant. (1970) (0)
- Intraalveolar metabolism of lung surfactant: role of SP-A in regulating surfactant pool size (1990) (0)
- Structure-Function Relationships in Lung Surfactant1 (1987) (0)
- COMPARISON OF VENTILATION OF A HIGH RESISTANCE-LOW COMPLIANCE PNEUMATIC SYSTEM (GAS CASUALTY MODEL) BY MOUTH-TO-MASK IN-SUFFLATION AND BY A PORTABLE HAND BELLOWS (1954) (0)
- Oral ketamine (1984) (0)
- Exogenous Surfactant for Human Lung Disease (2015) (0)
- Adhesion molecules in disease: vascular cell adhesion molecule-1 as a target for therapy (1996) (0)
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