John Christopher Lindon
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John Christopher Lindonchemistry Degrees
Chemistry
#1941
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Analytical Chemistry
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John Christopher Lindonbiology Degrees
Biology
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Computational Biology
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Chemistry Biology
John Christopher Lindon's Degrees
- PhD Chemistry University of Oxford
- Bachelors Chemistry University of Oxford
Why Is John Christopher Lindon Influential?
(Suggest an Edit or Addition)John Christopher Lindon's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. (1999) (3346)
- Proposed minimum reporting standards for chemical analysis (2007) (3098)
- Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts (2007) (1777)
- Metabonomics: a platform for studying drug toxicity and gene function (2002) (1762)
- Systems biology: Metabonomics (2008) (1608)
- Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice (2006) (983)
- 750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma. (1995) (885)
- Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets. (2005) (776)
- Pharmaco-metabonomic phenotyping and personalized drug treatment (2006) (765)
- Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism (2009) (666)
- Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies. (2005) (538)
- Improved WATERGATE Pulse Sequences for Solvent Suppression in NMR Spectroscopy (1998) (499)
- Scaling and normalization effects in NMR spectroscopic metabonomic data sets. (2006) (473)
- A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model (2007) (463)
- Metabolic phenotyping in clinical and surgical environments (2012) (445)
- NMR Spectroscopy Using Liquid Crystal Solvents (1975) (438)
- Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids (2000) (438)
- NMR‐based metabonomic approaches for evaluating physiological influences on biofluid composition (2005) (432)
- Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis (2004) (428)
- Probiotic modulation of symbiotic gut microbial–host metabolic interactions in a humanized microbiome mouse model (2008) (421)
- Pattern recognition methods and applications in biomedical magnetic resonance (2001) (397)
- The Metabolomics Standards Initiative (2007) (395)
- Encyclopedia of spectroscopy and spectrometry (2000) (378)
- NMR Spectroscopy of Biofluids (1999) (378)
- The metabolomics standards initiative (MSI) (2007) (377)
- Precision high-throughput proton NMR spectroscopy of human urine, serum, and plasma for large-scale metabolic phenotyping. (2014) (370)
- Colonization-Induced Host-Gut Microbial Metabolic Interaction (2011) (361)
- Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project. (2003) (355)
- Susceptibility of human metabolic phenotypes to dietary modulation. (2006) (350)
- High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues (2010) (337)
- The challenges of modeling mammalian biocomplexity (2004) (330)
- Assessment of analytical reproducibility of 1H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP Study. (2006) (325)
- The handbook of metabonomics and metabolomics (2007) (303)
- Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies. (2006) (299)
- Recursive segment-wise peak alignment of biological (1)h NMR spectra for improved metabolic biomarker recovery. (2009) (298)
- Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls. (2010) (297)
- Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics. (2008) (296)
- NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. (2008) (290)
- Metabonomics in pharmaceutical R & D (2007) (265)
- Chemometric models for toxicity classification based on NMR spectra of biofluids. (2000) (258)
- Metabonomics Techniques and Applications to Pharmaceutical Research & Development (2006) (255)
- Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins. (1998) (253)
- Analytical reproducibility in (1)H NMR-based metabonomic urinalysis. (2002) (247)
- The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements. (2005) (247)
- Optimized preprocessing of ultra-performance liquid chromatography/mass spectrometry urinary metabolic profiles for improved information recovery. (2011) (238)
- An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy. (2003) (225)
- Resolution enhancement in FT NMR through the use of a double exponential function (1978) (219)
- Digitisation and data processing in Fourier transform NMR (1980) (211)
- Development of a model for classification of toxin‐induced lesions using 1H NMR spectroscopy of urine combined with pattern recognition (1998) (207)
- Automatic data reduction and pattern recognition methods for analysis of 1H nuclear magnetic resonance spectra of human urine from normal and pathological states. (1994) (205)
- Use of relaxation-edited one-dimensional and two dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma. (2004) (204)
- Summary recommendations for standardization and reporting of metabolic analyses (2005) (198)
- Cryogenic probe 13C NMR spectroscopy of urine for metabonomic studies. (2002) (181)
- Species variation in the fecal metabolome gives insight into differential gastrointestinal function. (2008) (179)
- Improved analysis of multivariate data by variable stability scaling: application to NMR-based metabolic profiling (2003) (178)
- Metabonomic investigations into hydrazine toxicity in the rat. (2001) (173)
- Application of pattern recognition methods to the analysis and classification of toxicological data derived from proton nuclear magnetic resonance spectroscopy of urine. (1991) (172)
- Metabonomics and its role in drug development and disease diagnosis (2004) (172)
- Panorganismal gut microbiome-host metabolic crosstalk. (2009) (167)
- Human metabolic phenotypes link directly to specific dietary preferences in healthy individuals. (2007) (164)
- Combined HPLC, NMR spectroscopy, and ion-trap mass spectrometry with application to the detection and characterization of xenobiotic and endogenous metabolites in human urine. (1996) (164)
- So what's the deal with metabonomics? (2003) (163)
- Nuclear magnetic resonance spectroscopy and pattern recognition analysis of the biochemical processes associated with the progression of and recovery from nephrotoxic lesions in the rat induced by mercury(II) chloride and 2-bromoethanamine. (1992) (162)
- Investigations into biochemical changes due to diurnal variation and estrus cycle in female rats using high-resolution (1)H NMR spectroscopy of urine and pattern recognition. (2001) (161)
- Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development. (2000) (156)
- Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach. (2007) (156)
- The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine (1998) (153)
- Human metabolic profiles are stably controlled by genetic and environmental variation (2011) (151)
- High‐resolution magic angle spinning 1H NMR spectroscopic studies on intact rat renal cortex and medulla (1999) (150)
- 750 MHz 1H NMR spectroscopy characterisation of the complex metabolic pattern of urine from patients with inborn errors of metabolism: 2-hydroxyglutaric aciduria and maple syrup urine disease. (1997) (149)
- Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse. (2004) (148)
- HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies. (2011) (147)
- Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery (2008) (144)
- High‐resolution 1H and 1H‐13C magic angle spinning NMR spectroscopy of rat liver (2000) (144)
- NMR-based metabonomic toxicity classification: hierarchical cluster analysis and k-nearest-neighbour approaches (2003) (141)
- Pattern recognition classification of the site of nephrotoxicity based on metabolic data derived from proton nuclear magnetic resonance spectra of urine. (1994) (140)
- The comparison of plasma deproteinization methods for the detection of low-molecular-weight metabolites by (1)H nuclear magnetic resonance spectroscopy. (2002) (136)
- Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues. (2003) (133)
- Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles. (2004) (131)
- High-resolution diffusion and relaxation edited one- and two-dimensional 1H NMR spectroscopy of biological fluids. (1996) (129)
- A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection (2011) (129)
- Stability and robustness of human metabolic phenotypes in response to sequential food challenges. (2012) (126)
- NMR spectroscopy as a novel approach to the monitoring of renal transplant function. (1993) (126)
- Pharmacometabonomics as an effector for personalized medicine. (2011) (123)
- Environmental Metabonomics: Applying Combination Biomarker Analysis in Earthworms at a Metal Contaminated Site (2004) (123)
- Robust data processing and normalization strategy for MALDI mass spectrometric imaging. (2012) (122)
- Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by 1H NMR Spectroscopy in a Multilaboratory Trial. (2018) (120)
- Biochemical classification of kidney carcinoma biopsy samples using magic-angle-spinning 1H nuclear magnetic resonance spectroscopy. (1998) (118)
- Metabonomic assessment of toxicity of 4‐fluoroaniline, 3,5‐difluoroaniline and 2‐fluoro‐4‐methylaniline to the earthworm Eisenia veneta (rosa): Identification of new endogenous biomarkers (2002) (117)
- Toxicological applications of magnetic resonance (2004) (113)
- A metabolic system-wide characterisation of the pig: a model for human physiology. (2011) (112)
- Comparative metabonomics of differential hydrazine toxicity in the rat and mouse. (2005) (110)
- Acyl glucuronides: biological activity, chemical reactivity, and chemical synthesis. (2006) (110)
- Metabonomic studies on the physiological effects of acute and chronic psychological stress in Sprague-Dawley rats. (2007) (109)
- Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy. (2007) (109)
- Direct coupling of chromatographic separations to NMR spectroscopy (1996) (106)
- High-resolution magic angle spinning (1)H NMR spectroscopy of intact liver and kidney: optimization of sample preparation procedures and biochemical stability of tissue during spectral acquisition. (2000) (106)
- Metabolic assessment of human liver transplants from biopsy samples at the donor and recipient stages using high-resolution magic angle spinning 1H NMR spectroscopy. (2005) (103)
- Identification of human urinary biomarkers of cruciferous vegetable consumption by metabonomic profiling. (2011) (100)
- Directly coupled HPLC-NMR and its application to drug metabolism. (1997) (100)
- Ultra high field NMR spectroscopic studies on human seminal fluid, seminal vesicle and prostatic secretions. (1994) (98)
- Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model (2008) (98)
- High-resolution magic angle spinning NMR spectroscopy: Application to biomedical studies (2009) (97)
- 1H NMR spectroscopy-based interventional metabolic phenotyping: a cohort study of rheumatoid arthritis patients. (2010) (95)
- High resolution magic angle spinning 1H nuclear magnetic resonance analysis of intact prostatic hyperplastic and tumour tissues (1998) (95)
- An NMR‐based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress (2001) (95)
- Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping. (2016) (93)
- Metabonomics: systems biology in pharmaceutical research and development. (2004) (93)
- Metabolomics Standards Workshop and the development of international standards for reporting metabolomics experimental results (2006) (93)
- Evaluation of full-resolution J-resolved 1H NMR projections of biofluids for metabonomics information retrieval and biomarker identification. (2010) (92)
- Hyperspectral visualization of mass spectrometry imaging data. (2013) (91)
- Analysis of biological fluids using 600 MHz proton NMR spectroscopy: application of homonuclear two-dimensional J-resolved spectroscopy to urine and blood plasma for spectral simplification and assignment. (1993) (91)
- Automatic alignment of individual peaks in large high-resolution spectral data sets. (2004) (90)
- UPLC-MS metabolic profiling of second trimester amniotic fluid and maternal urine and comparison with NMR spectral profiling for the identification of pregnancy disorder biomarkers. (2012) (90)
- Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease (2019) (89)
- Effects of probiotic Lactobacillus paracasei treatment on the host gut tissue metabolic profiles probed via magic-angle-spinning NMR spectroscopy. (2007) (87)
- Distinction between normal and renal cell carcinoma kidney cortical biopsy samples using pattern recognition of 1H magic angle spinning (MAS) NMR spectra (2000) (87)
- Pattern recognition analysis of high resolution 1H NMR spectra of urine. A nonlinear mapping approach to the classification of toxicological data (1990) (87)
- Earthworm species of the genus Eisenia can be phenotypically differentiated by metabolic profiling (2002) (86)
- Measurement of biomolecular diffusion coefficients in blood plasma using two-dimensional 1H-1H diffusion-edited total-correlation NMR spectroscopy. (1997) (83)
- An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. (2006) (83)
- NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat. (2010) (82)
- Batch statistical processing of 1H NMR‐derived urinary spectral data (2002) (80)
- Ultra performance liquid chromatography-mass spectrometry profiling of bile acid metabolites in biofluids: application to experimental toxicology studies. (2010) (80)
- Production of colominic acid by Pasteurella haemolytica serotype A2 organisms (1987) (80)
- Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation. (2006) (80)
- 600 MHz 1H-NMR spectroscopy of human cerebrospinal fluid: effects of sample manipulation and assignment of resonances. (1993) (79)
- Purification, characterization and immunological properties of the serotype-specific capsular polysaccharide of Pasteurella haemolytica (serotype A1) organisms. (1984) (78)
- Statistical experimental design and partial least squares regression analysis of biofluid metabonomic nmr and clinical chemistry data for screening of adverse drug effects (2004) (74)
- Topographical variation in metabolic signatures of human gastrointestinal biopsies revealed by high-resolution magic-angle spinning 1H NMR spectroscopy. (2007) (74)
- Subset optimization by reference matching (STORM): an optimized statistical approach for recovery of metabolic biomarker structural information from 1H NMR spectra of biofluids. (2012) (74)
- The influence of EDTA and citrate anticoagulant addition to human plasma on information recovery from NMR-based metabolic profiling studies. (2010) (74)
- The emergent role of metabolic phenotyping in dynamic patient stratification (2014) (73)
- Experimental metabonomic model of dietary variation and stress interactions. (2006) (73)
- Toxicity classification from metabonomic data using a density superposition approach: ‘CLOUDS’ (2003) (72)
- Statistical spectroscopic tools for biomarker discovery and systems medicine. (2013) (70)
- Statistical correlation and projection methods for improved information recovery from diffusion-edited NMR spectra of biological samples. (2007) (69)
- The biochemical profile of rat testicular tissue as measured by magic angle spinning 1H NMR spectroscopy (2000) (69)
- Tautomerism in 2‐hydroxy‐1‐naphthaldehyde schiff bases in solution and the solid state investigated using 13C NMR spectroscopy (1993) (68)
- Topographical variation in murine intestinal metabolic profiles in relation to microbiome speciation and functional ecological activity. (2009) (67)
- Directly Coupled 800 MHz HPLC−NMR Spectroscopy of Urine and Its Application to the Identification of the Major Phase II Metabolites of Tolfenamic Acid (1997) (66)
- Magic Angle Spinning Proton Nuclear Magnetic Resonance Spectroscopic Analysis of Intact Kidney Tissue Samples (1997) (64)
- Peer Reviewed: So What’s the Deal with Metabonomics? (2003) (63)
- Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy (2012) (61)
- Classification of toxin-induced changes in 1H NMR spectra of urine using an artificial neural network. (1995) (60)
- Targeting the human genome-microbiome axis for drug discovery: inspirations from global systems biology and traditional Chinese medicine. (2012) (60)
- Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen. (2001) (60)
- Omics and its potential impact on R&D and regulation of complex herbal products. (2012) (60)
- The mechanism of galactosamine toxicity revisited; a metabonomic study. (2007) (59)
- Temporal metabonomic modeling of l-arginine-induced exocrine pancreatitis. (2008) (58)
- An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria (2003) (58)
- Coupling of HPLC with 19F- and 1H-NMR spectroscopy to investigate the human urinary excretion of flurbiprofen metabolites. (1993) (58)
- Detection of in vivo biomarkers of phospholipidosis using NMR‐based metabonomic approaches (2001) (58)
- Biochemical characterization of rat intestine development using high-resolution magic-angle-spinning 1H NMR spectroscopy and multivariate data analysis. (2005) (57)
- Evaluation of liquid chromatography coupled with high‐field 1H NMR spectroscopy for drug metabolite detection and characterization: The identification of paracetamol metabolites in urine and bile (1994) (56)
- Genetic algorithms for simultaneous variable and sample selection in metabonomics (2009) (55)
- Uroscopy in the 21st century: high-field NMR spectroscopy. (1997) (55)
- NMR-based metabonomic studies on the biochemical effects of commonly used drug carrier vehicles in the rat. (2002) (55)
- Identifying unknown metabolites using NMR-based metabolic profiling techniques (2020) (54)
- Robust algorithms for automated chemical shift calibration of 1D 1H NMR spectra of blood serum. (2008) (54)
- Use of 1H NMR‐determined diffusion coefficients to characterize lipoprotein fractions in human blood plasma (2002) (52)
- Optimization of human plasma 1H NMR spectroscopic data processing for high-throughput metabolic phenotyping studies and detection of insulin resistance related to type 2 diabetes. (2008) (52)
- NMR spectroscopy of human post mortem cerebrospinal fluid: Distinction of Alzheimer's disease from control using pattern recognition and statistics (1993) (52)
- Studies of Tautomerism in 2-Hydroxynaphthaldehyde Schiff Bases by Multinuclear Magnetic Resonance (1991) (51)
- Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome (2021) (51)
- NMR-based metabonomic studies on the biochemical effects of epicatechin in the rat. (2003) (51)
- 19F-NMR and directly coupled HPLC-NMR-MS investigations into the metabolism of 2-bromo-4-trifluoromethylaniline in rat: a urinary excretion balance study without the use of radiolabelling. (1998) (50)
- An integrated molecular and immunological approach towards a meningococcal group B vaccine. (1987) (49)
- Identification of metabolites in human hepatic bile using 800 MHz 1H NMR spectroscopy, HPLC-NMR/MS and UPLC-MS. (2009) (48)
- Intra- and interlaboratory reproducibility of ultra performance liquid chromatography-time-of-flight mass spectrometry for urinary metabolic profiling. (2012) (48)
- A metabonomic investigation of hepatotoxicity using diffusion-edited 1H NMR spectroscopy of blood serum. (2003) (47)
- Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation. (2008) (46)
- High-performance liquid chromatography linked to inductively coupled plasma mass spectrometry and orthogonal acceleration time-of-flight mass spectrometry for the simultaneous detection and identification of metabolites of 2-bromo-4-trifluoromethyl. (2001) (46)
- Directly coupled CZE-NMR and CEC-NMR spectroscopy for metabolite analysis: paracetamol metabolites in human urine. (1998) (46)
- Characterisation of impurities in bulk drug batches of fluticasone propionate using directly coupled HPLC-NMR spectroscopy and HPLC-MS. (1997) (46)
- A comparison of quantitative NMR and radiolabelling studies of the metabolism and excretion of Statil (3-(4-bromo-2-fluorobenzyl)-4-oxo-3H-phthalazin-1-ylacetic acid) in the rat. (2002) (45)
- Application of directly coupled LC-NMR-MS to the structural elucidation of metabolites of the HIV-1 reverse-transcriptase inhibitor BW935U83. (2000) (45)
- Statistical total correlation spectroscopy editing of 1H NMR spectra of biofluids: application to drug metabolite profile identification and enhanced information recovery. (2009) (45)
- Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylaniline in the rat using 19F-NMR spectroscopy and directly coupled HPLC-NMR-MS. (1999) (45)
- Mapping the biochemical trajectory of nephrotoxicity by pattern recognition of NMR urinanalysis (1992) (45)
- Qualitative high field 1H-NMR spectroscopy for the characterization of endogenous metabolites in earthworms with biochemical biomarker potential (2005) (44)
- Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis. (2006) (44)
- Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status (2004) (44)
- Magic angle spinning NMR and 1H-31P heteronuclear statistical total correlation spectroscopy of intact human gut biopsies. (2008) (44)
- Nuclear magnetic resonance and high-performance liquid chromatography-nuclear magnetic resonance studies on the toxicity and metabolism of ifosfamide. (1996) (43)
- Data-driven approach for metabolite relationship recovery in biological 1H NMR data sets using iterative statistical total correlation spectroscopy. (2011) (42)
- Impurity profiling in bulk pharmaceutical batches using 19F NMR spectroscopy and distinction between monomeric and dimeric impurities by NMR-based diffusion measurements. (1999) (42)
- Heteronuclear 1H-31P statistical total correlation NMR spectroscopy of intact liver for metabolic biomarker assignment: application to galactosamine-induced hepatotoxicity. (2007) (42)
- High performance liquid chromatography coupled to nuclear magnetic resonance spectroscopy and mass spectrometry applied to plant products: Identification of ecdysteroids fromSilene otites (1999) (42)
- Separation and characterization of components of peptide libraries using on‐flow coupled HPLC—NMR spectroscopy (1995) (41)
- Quantitative structure-metabolism relationships for substituted benzoic acids in the rat. Computational chemistry, NMR spectroscopy and pattern recognition studies. (1992) (41)
- Bile UPLC‐MS fingerprinting and bile acid fluxes during human liver transplantation (2011) (40)
- Analysis of Drug–Protein Binding Using Nuclear MagneticResonance Based Molecular Diffusion Measurements (1997) (40)
- Application of directly coupled HPLC-NMR-MS/MS to the identification of metabolites of 5-trifluoromethylpyridone (2-hydroxy-5-trifluoromethylpyridine) in hydroponically grown plants. (2000) (39)
- Direct observation of resolved intracellular and extracellular water signals in intact human red blood cells using 1H MAS NMR spectroscopy (1997) (39)
- A rapid and facile method for the dereplication of purified natural products. (2001) (39)
- Liquid chromatography-mass spectrometry methods for urinary biomarker detection in metabonomic studies with application to nutritional studies. (2009) (39)
- 750 MHz HPLC-NMR spectroscopic studies on the separation and characterization of the positional isomers of the glucuronides of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid. (1996) (38)
- Mass spectrometrically detected directly coupled high performance liquid chromatography/nuclear magnetic resonance spectroscopy/mass spectrometry for the identification of xenobiotic metabolites in maize plants. (2000) (38)
- NMR Spectroscopic Windows on the Systemic Effects of SARS-CoV-2 Infection on Plasma Lipoproteins and Metabolites in Relation to Circulating Cytokines. (2021) (38)
- Processing and modeling of nuclear magnetic resonance (NMR) metabolic profiles. (2011) (38)
- NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues. (2007) (38)
- On-flow identification of metabolites of paracetamol from human urine using directly coupled CZE–NMR and CEC–NMR spectroscopy (1998) (38)
- Integrated Analytical and Statistical Two-Dimensional Spectroscopy Strategy for Metabolite Identification: Application to Dietary Biomarkers (2017) (38)
- Mass directed peak selection, an efficient method of drug metabolite identification using directly coupled liquid chromatography-mass spectrometry-nuclear magnetic resonance spectroscopy. (2000) (37)
- Flow Injection Proton Nuclear Magnetic Resonance Spectroscopy Combined With Pattern Recognition Methods: Implications for Rapid Structural Studies and High Throughput Biochemical Screening (1997) (37)
- High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: application to the metabolites of 4-bromoaniline. (2000) (37)
- 1H and 2H NMR spectroscopic studies on the metabolism and biochemical effects of 2-bromoethanamine in the rat. (1995) (37)
- Cluster analysis statistical spectroscopy using nuclear magnetic resonance generated metabolic data sets from perturbed biological systems. (2009) (37)
- Identification of the Positional Isomers of 2-Fluorobenzoic acid 1-O-Acyl Glucuronide by Directly Coupled HPLC-NMR (1995) (37)
- Evaluation of high resolution magic-angle coil spinning NMR spectroscopy for metabolic profiling of nanoliter tissue biopsies. (2012) (36)
- The urinary proteome and metabonome differ from normal in adults with mitochondrial disease. (2015) (35)
- Workflow for Integrated Processing of Multicohort Untargeted 1H NMR Metabolomics Data in Large-Scale Metabolic Epidemiology. (2016) (34)
- Metabolism of 4-fluoroaniline and 4-fluorobiphenyl in the earthworm Eisenia veneta characterized by high-resolution NMR spectroscopy with directly coupled HPLC-NMR and HPLC-MS (2002) (34)
- Chiral metabonomics: 1H NMR-based enantiospecific differentiation of metabolites in human urine via direct cosolvation with β-cyclodextrin. (2012) (34)
- Direct characterization of drug glucuronide isomers in human urine by HPLC-NMR spectroscopy: application to the positional isomers of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid glucuronide. (1996) (34)
- Large-scale human metabolic phenotyping and molecular epidemiological studies via 1H NMR spectroscopy of urine: investigation of borate preservation. (2009) (34)
- Metabonomics in toxicity assessment (2005) (34)
- Evaluation of metabolic variation in normal rat strains from a statistical analysis of 1H NMR spectra of urine. (2004) (33)
- 750-MHz directly coupled HPLC-NMR: Application for the sequential characterization of the positional isomers and anomers of 2-, 3-, and 4-fluorobenzoic acid glucuronides in equilibrium mixtures (1995) (33)
- Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response. (2012) (33)
- Mechanistic aspects and novel biomarkers of responder and non-responder phenotypes in galactosamine-induced hepatitis. (2009) (33)
- 1H, 13C and 31P n.m.r. spectra and molecular conformation of myo-inositol 1,4,5-triphosphate. (1986) (33)
- Nuclear magnetic resonance (NMR) and quantitative structure–activity relationship (QSAR) studies on the transacylation reactivity of model 1β-O-acyl glucuronides. II: QSAR modelling of the reaction using both computational and experimental NMR parameters (2004) (33)
- NMR spectroscopic studies on the haemolymph of the tobacco hornworm, Manduca sexta: assignment of 1H and 13C NMR spectra (1999) (33)
- Studies of the biochemical toxicology of uranyl nitrate in the rat (2009) (33)
- Pharmacometabonomic investigation of dynamic metabolic phenotypes associated with variability in response to galactosamine hepatotoxicity. (2012) (32)
- Conformational and dynamic differences between N. meningitidis serogroup B and C polysaccharides, using n.m.r. spectroscopy and molecular mechanics calculations. (1984) (32)
- Quantitative structure-metabolism relationships (QSMR) using computational chemistry: pattern recognition analysis and statistical prediction of phase II conjugation reactions of substituted benzoic acids in the rat. (1999) (31)
- Internal temperature calibration for 1H NMR spectroscopy studies of blood plasma and other biofluids (1994) (31)
- Investigation of the human metabolism of antipyrine using coupled liquid chromatography and nuclear magnetic resonance spectroscopy of urine. (1993) (31)
- Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions. (2008) (31)
- High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat. (1995) (31)
- Measurement of Internal Acyl Migration Reaction Kinetics Using Directly Coupled HPLC-NMR: Application for the Positional Isomers of Synthetic (2-Fluorobenzoyl)-d-glucopyranuronic Acid. (1996) (31)
- Characterization of Metabolites in IntactStreptomyces citricolorCulture Supernatants Using High-Resolution Nuclear Magnetic Resonance and Directly Coupled High-Pressure Liquid Chromatography–Nuclear Magnetic Resonance Spectroscopy☆ (1999) (31)
- Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets. (2004) (30)
- Quantitative structure-metabolism relationships for substituted benzoic acids in the rabbit: prediction of urinary excretion of glycine and glucuronide conjugates. (1996) (30)
- Dynamic biochemical information recovery in spontaneous human seminal fluid reactions via 1H NMR kinetic statistical total correlation spectroscopy. (2009) (29)
- NMR spectroscopic and theoretical chemistry studies on the internal acyl migration reactions of the 1-O-acyl-beta-D-glucopyranuronate conjugates of 2-, 3-, and 4-(trifluoromethyl) benzoic acids. (1996) (29)
- Nuclear magnetic resonance studies of magnetohydrodynamic effects in the nematic mesophase (1973) (29)
- An automatic data reduction and transfer method to aid pattern recognition analysis and classification of NMR spectra. (1992) (29)
- Characterization and quantification of metabolites of racemic ketoprofen excreted in urine following oral administration to man by 1H-NMR spectroscopy, directly coupled HPLC-MS and HPLC-NMR, and circular dichroism (2004) (28)
- Quantitative structure-toxicity relationships for halogenated substituted-benzenes to Vibrio fischeri, using atom-based semi-empirical molecular-orbital descriptors. (1999) (28)
- Chapter 1 – Metabonomics and Metabolomics Techniques and Their Applications in Mammalian Systems (2007) (28)
- Cephaloridine-induced nephrotoxicity in the Fischer 344 rat: proton NMR spectroscopic studies of urine and plasma in relation to conventional clinical chemical and histopathological assessments of nephronal damage (2005) (27)
- A metabolic entropy approach for measurements of systemic metabolic disruptions in patho-physiological States. (2010) (27)
- Hplc-nmr identification of the human urinary metabolites of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analogue active against human immunodeficiency virus (HIV). (1996) (27)
- ¹H NMR-based metabonomics for investigating diabetes. (2009) (27)
- S-naproxen-beta-1-O-acyl glucuronide degradation kinetic studies by stopped-flow high-performance liquid chromatography-1H NMR and high-performance liquid chromatography-UV. (2001) (27)
- Selective Inverse-Detected Long-Range HeteronuclearJ-Resolved NMR Spectroscopy and Its Application to the Measurement of3JCH (1995) (26)
- Quantitation in gradient high performance liquid chromatography/inductively coupled mass spectrometry investigated using diclofenac and chlorpromazine. (2002) (26)
- Optimized Phenotypic Biomarker Discovery and Confounder Elimination via Covariate-Adjusted Projection to Latent Structures from Metabolic Spectroscopy Data (2018) (26)
- NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man. (1997) (26)
- Statistical total correlation spectroscopy scaling for enhancement of metabolic information recovery in biological NMR spectra. (2012) (26)
- Use of directly coupled ion-exchange liquid chromatography-mass spectrometry and liquid chromatography-nuclear magnetic resonance spectroscopy as a strategy for polar metabolite identification. (2000) (25)
- Application of resolution enhancement to absolute value presentation of FT NMR spectra (1979) (25)
- Metabolism of 3-chloro-4-fluoroaniline in rat using [14C]-radiolabelling, 19F-NMR spectroscopy, HPLC-MS/MS, HPLC-ICPMS and HPLC-NMR (2006) (25)
- Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase. (2012) (25)
- Application of directly coupled HPLC NMR to separation and characterization of lipoproteins from human serum. (2001) (25)
- Chain ordering in the nematic mesophase of 4-cyano-4′-n-pentylbiphenyl (1975) (25)
- A metabonomic analysis of insect development: 1H-NMR spectroscopic characterization of changes in the composition of the haemolymph of larvae and pupae of the tobacco hornworm, Manduca sexta (2008) (25)
- Biodegradable neuromuscular blocking agents. VI: Stereochemical studies on atracurium and related polyalkylene di-esters (1984) (25)
- Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples (2020) (25)
- High‐Resolution Magic Angle Spinning NMR Spectroscopy: Application to Biomedical Studies (2010) (24)
- Characterization of in vitro metabolites from human liver microsomes using directly coupled hplc-nmr: application to a phenoxathiin monoamine oxidase-A inhibitor. (1996) (24)
- Investigation of the metabolite variation in control rat urine using (1)H NMR spectroscopy. (2001) (24)
- A comparison of human serum and plasma metabolites using untargeted 1H NMR spectroscopy and UPLC-MS (2018) (24)
- N.M.R. spectra of ethanol and partially deuterated ethanols as solutes in a nematic phase (1973) (23)
- Prediction of urinary sulphate and glucuronide conjugate excretion for substituted phenols in the rat using quantitative structure-metabolism relationships. (1995) (23)
- Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1beta-O-acyl glucuronides. (2009) (23)
- Recent advances in high-resolution NMR spectroscopic methods in bioanalytical chemistry (1997) (23)
- 1H and 19F-nmr spectroscopic studies on the metabolism and urinary excretion of mono- and disubstituted phenols in the rat. (1996) (23)
- Application of the one-dimensional TOCSY pulse sequence in 750 MHz 1H-NMR spectroscopy for assignment of endogenous metabolite resonances in biofluids. (1994) (23)
- LC-1H NMR used for determination of the elution order of S-naproxen glucuronide isomers in two isocratic reversed-phase LC-systems. (2001) (22)
- The potential of 19F NMR spectroscopy for rapid screening of cell cultures for models of mammalian drug metabolism. (2001) (22)
- High-performance liquid chromatography-UV diode array, inductively coupled plasma mass spectrometry (ICMPS) and orthogonal acceleration time-of-flight mass spectrometry (oa-TOFMS) applied to the simultaneous detection and identification of metabolites of 4-bromoaniline in rat urine (2002) (22)
- Self-modeling curve resolution recovery of temporal metabolite signal modulation in NMR spectroscopic data sets: application to a life-long caloric restriction study in dogs. (2008) (22)
- NMR and QSAR studies on the transacylation reactivity of model 1β-O-acyl glucuronides. I: design, synthesis and degradation rate measurement (2004) (22)
- Integrated HPLC-MS and 1H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides (2010) (22)
- Multiplatform serum metabolic phenotyping combined with pathway mapping to identify biochemical differences in smokers. (2016) (22)
- A pattern recognition approach to the comparison of PMR and clinical chemical data for classification of nephrotoxicity. (1990) (21)
- Effect of vibrational averaging on the quadrupole coupling constant of deuterium in 4-[2H1] pyridine determined from 1H–{2H} INDOR n.m.r. of a partially oriented sample (1975) (20)
- Measurement of deuterium quadrupole coupling constants of CD3 groups by 1H−{2H} N.M.R. studies of nematic solutions (1973) (20)
- Directly Coupled Chiral HPLC−NMR and HPLC−CD Spectroscopy as Complementary Methods for Structural and Enantiomeric Isomer Identification: Application to Atracurium Besylate (1999) (20)
- A Statistically Rigorous Test for the Identification of Parent−Fragment Pairs in LC-MS Datasets (2010) (20)
- Application of directly coupled high-performance liquid chromatography-nuclear magnetic resonance-mass spectrometry to the detection and characterisation of the metabolites of 2-bromo-4-trifluoromethylaniline in rat urine (1997) (20)
- Purification, characterization and immunological properties of the capsular polysaccharide of Pasteurella haemolytica serotype T15: its identity with the K62 (K2ab) capsular polysaccharide of Escherichia coli and the capsular polysaccharide of Neisseria meningitidis serogroup H. (1985) (20)
- A Unified Conceptual Framework for Metabolic Phenotyping in Diagnosis and Prognosis. (2019) (20)
- Diffusion and Relaxation Edited Proton NMR Spectroscopy of Plasma Reveals a High-Fidelity Supramolecular Biomarker Signature of SARS-CoV-2 Infection (2021) (20)
- High-performance liquid chromatography directly coupled to 19F and 1H NMR for the analysis of mixtures of isomeric ester glucuronide conjugates of trifluoromethylbenzoic acids (1996) (19)
- Enhanced effect of magnetic field gradients using multiple quantum NMR spectroscopy applied to self-diffusion coefficient measurement (1998) (19)
- Improving Visualization and Interpretation of Metabolome-Wide Association Studies: An Application in a Population-Based Cohort Using Untargeted 1H NMR Metabolic Profiling (2017) (19)
- Seminal oligouridinosis: low uridine secretion as a biomarker for infertility in spinal neurotrauma. (2008) (19)
- Identification of the urinary metabolites of 4-bromoaniline and 4-bromo- [carbonyl - 13 C]-acetanilide in rat (2002) (19)
- Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat. (1999) (19)
- NMR spectroscopic studies of the transacylation reactivity of ibuprofen 1-beta-O-acyl glucuronide. (2006) (19)
- Double resonance nuclear magnetic resonance spectra of partially aligned molecules (1973) (18)
- The development and application of coupled HPLC-NMR spectroscopy. (1996) (18)
- Development of a simple liquid chromatographic method for the separation of mixtures of positional isomers and anomers of synthetic 2-, 3- and 4-fluorobenzoic acid glucuronides formed via acyl migration reactions. (1996) (17)
- Recovery of underwater resonances by magnetization transferred NMR spectroscopy (RECUR-NMR). (2001) (17)
- NMR Spectroscopy: Principles and Instrumentation (2005) (17)
- Investigation of the metabolism of 14C/13C-practolol in rat using directly coupled radio-HPLC-NMR-MS (2000) (17)
- Determination of the relative NH proton lifetimes of the peptide analogue viomycin in aqueous solution by NMR-based diffusion measurement (1999) (17)
- Application of CE-MS to a metabonomics study of human urine from cigarette smokers and non-smokers. (2014) (17)
- Can joint fluid metabolic profiling (or “metabonomics”) reveal biomarkers for osteoarthritis and inflammatory joint disease? (2020) (17)
- Selective Detection of 1H NMR Resonances of CHn Groups Using a Heteronuclear Maximum-Quantum Filter and Pulsed Field Gradients (1995) (17)
- 750 MHz HPLC-NMR spectroscopic identification of rat microsomal metabolites of phenoxypyridines. (1997) (17)
- Structural and conformational features of the Escherichia coli K92 capsular polysaccharide. (1985) (17)
- Absolute metabolite quantification by in vivo NMR spectroscopy: V. Multicentre quantitative data analysis trial on the overlapping background problem. (1998) (17)
- Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1‐cyano‐2‐hydroxy‐3‐butene in the rat (2009) (16)
- Assignment of the peaks in a carbon-13 NMR spectrum by off-resonance irradiation of strongly coupled protons (1973) (16)
- Sites of protonation in cardiotonic polyazaindolizines by NMR spectroscopy (1991) (16)
- Structure and conformation of 4,4′-bipyridyl by nuclear magnetic resonance spectroscopy of a nematic solution (1976) (16)
- Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series (2016) (16)
- 1H, 13C and 15N NMR observations on the protonation of 1‐ and 3‐deazapurine (1986) (16)
- Kinetic studies on the intramolecular acyl migration of β-1-O-acyl glucuronides: Application to the glucuronides of (R)- and (S)-ketoprofen, (R)- and (S)-hydroxy-ketoprofen metabolites, and tolmetin by 1H-NMR spectroscopy (2005) (16)
- NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat. (1997) (16)
- NMR of biofluids: detection of 2H-acetate and 2H-formate in urine as an indicator of microbiological contamination. (1993) (15)
- J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis. (2017) (15)
- The confromational behaviour of the cardiac glycoside digoxin as indicated by NMR spectroscopy and molecular dynamics calculations (1992) (15)
- Lipid characterization in an animal model of atherosclerosis using NMR spectroscopy and imaging (1990) (15)
- Conformation of ethane‐1,2‐diol from analysis of its NMR spectrum obtained using gradient‐enhanced inverse detection (1993) (15)
- Non-linear modeling of 1H NMR metabonomic data using kernel-based orthogonal projections to latent structures optimized by simulated annealing. (2011) (15)
- First example of hepatocyte transplantation to alleviate ornithine transcarbamylase deficiency, monitored by NMR-based metabonomics. (2009) (15)
- Investigation of the quantitative metabolic fate and urinary excretion of 3-methyl-4-trifluoromethylaniline and 3-methyl-4-trifluoromethylacetanilide in the rat. (1999) (15)
- A high-performance liquid chromatography and nuclear magnetic resonance spectroscopy-based analysis of commercially available praziquantel tablets. (2007) (15)
- HPLC-NMR-MS: past, present and future. (2003) (15)
- The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR. (2002) (15)
- High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma. (2010) (15)
- Quantitative structure chromatography relationships in reversed-phase high performance liquid chromatography: Prediction of retention behaviour using theoretically derived molecular properties (1993) (15)
- Protonation equilibria of cardiotonic polyaza heterocycles (1989) (14)
- Hepatotoxin-induced hypertyrosinemia and its toxicological significance (2007) (14)
- Motion of the director in a spinning nematic subject to a static magnetic field (1981) (14)
- Confirmation of the identities of inositol 1,3,4-trisphosphate and inositol 1,3,4,5-tetrakisphosphate by the use of one-dimensional and two-dimensional n.m.r. spectroscopy. (1987) (14)
- Chemical shift calibration of 1H MAS NMR liver tissue spectra exemplified using a study of glycine protection of galactosamine toxicity (2009) (14)
- High-performance liquid chromatography/inductively coupled plasma mass spectrometry with iodine-specific detection for profiling the metabolites produced in the earthworm Eisenia veneta by exposure to 2-fluoro-4-iodoaniline. (2003) (13)
- Molecular rotation in liquid crystals selective deuterium spin-lattice relaxation times in the nemat (1976) (13)
- Selective Detection of 1H NMR Resonances of 13CHn Groups Using Two-Dimensional Maximum-Quantum Correlation Spectroscopy (1995) (13)
- The effect of vibrational averaging on the geometry of cyclobutadiene iron tricarbonyl derived from the proton N.M.R. spectrum of a nematic solution (1974) (13)
- Synthesis of a series of phenylacetic acid 1-β-O-acyl glucosides and comparison of their acyl migration and hydrolysis kinetics with the corresponding acyl glucuronides. (2011) (13)
- High-field deuterium nuclear magnetic resonance spectroscopic monitoring of the pharmacokinetics of selectively deuterated benzoic acid in man. (1994) (13)
- Integrated Histopathological and Urinary Metabonomic Investigation of the Pathogenesis of Microcystin-LR Toxicosis (2013) (13)
- Conformation and reorientation of acetophenone in solution. A proton and deuterium magnetic resonance study in a nematic solvent (1976) (13)
- Studies on the comparative toxicity of S-(1,2-dichlorovinyl)-L-cysteine, S-(1,2-dichlorovinyl)-L-homocysteine and 1,1,2-trichloro-3,3,3-trifluoro-1-propene in the Fischer 344 rat (2009) (12)
- 13C NMR studies of tautomerism in imidazo[4,5‐c]pyridines (1989) (12)
- Chapter 1 – Liquid crystals (1975) (12)
- Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanilic acid formation using computational chemistry (2002) (12)
- Spectroscopic and statistical methods in metabonomics. (2009) (12)
- NMR spectroscopic diffusion, chemical shift and linewidth measurements of low‐affinity binding of ibuprofen enantiomers to human serum albumin (1999) (12)
- Deuterium NMR spectroscopy of biofluids for the identification of drug metabolites: application to N,N-dimethylformamide. (1993) (12)
- An assessment of simple theories of chemical shifts of aromatic protons as applied to substituted naphthalenes (1973) (12)
- Two‐dimensional 1H1H and 13C1H maximum‐quantum correlation NMR spectroscopy with application to the assignment of the NMR spectra of the bile salt sodium taurocholate (1995) (12)
- Analysis of partially oriented AA′XX′ N.M.R. spin systems with the aid of sample rotation. The 19F spectrum of cis-difluoroethylene dissolved in a nematic phase (1974) (11)
- Separation of isotropic from anisotropic interactions in the NMR spectra of solutes dissolved in nematic mesophases by using slow sample rotation (1974) (11)
- Diffusion Coefficient Measurement by High Resolution NMR Spectroscopy: Biochemical and Pharmaceutical Applications (1999) (11)
- The N.M.R. spectrum of cyclopentadienyl manganese tricarbonyl partially oriented in a nematic solvent (1971) (11)
- Investigation of the feasibility of directly-coupled HPLC-NMR with 2H detection with application to the metabolism of N-dimethylformamide-d7. (1997) (11)
- An adventitious synthesis of a 5-methylimidazo[4,5-c]pyridine derivative (1986) (11)
- Quantitative structure-toxicity relationships for halobenzenes in two species of bioluminescent bacteria, Pseudomonas fluorescens and Vibrio fischeri, using an atom-centered semi-empirical molecular-orbital based model (1999) (11)
- The proton N.M.R. spectrum of partially oriented norbornadiene. Molecular structure and the effect of vibrational averaging (1975) (11)
- The metabolism of 2-trifluormethylaniline and its acetanilide in the rat by 19F NMR monitored enzyme hydrolysis and 1H/19F HPLC-NMR spectroscopy. (2003) (11)
- Proton NMR studies on the effects of uranyl nitrate on the biochemical composition of rat urine and plasma. (1990) (11)
- Differences in the composition of hip and knee synovial fluid in osteoarthritis: a nuclear magnetic resonance (NMR) spectroscopy study of metabolic profiles. (2019) (11)
- Multinuclear magnetic resonance study of tautomerism in fluorinated β‐diketones (1990) (11)
- A systematic review of the small molecule studies of osteoarthritis using nuclear magnetic resonance and mass spectroscopy. (2019) (11)
- Characterization of metabolites in intact Streptomyces citricolor culture supernatants using high-resolution nuclear magnetic resonance and directly coupled high-pressure liquid chromatography-nuclear magnetic resonance spectroscopy. (1999) (10)
- A QSAR investigation of dermal and respiratory chemical sensitizers based on computational chemistry properties (2009) (10)
- 19 F-NMR and directly coupled 19 F/ 1 H-HPLC-NMR spectroscopic investigations of the metabolism of the model ecotoxin 3-trifluoromethylaniline in the earthworm species Eisenia veneta (2002) (10)
- Proton shielding anisotropy in benzene (1970) (10)
- Metabolism of 2-fluoro-4-iodoaniline in earthworm Eisenia veneta using 19F-NMR spectroscopy, HPLC-MS, and HPLC-ICPMS (127I) (2007) (10)
- Discrimination between broad and sharp NMR signals and dynamic range improvement through Gaussian shaping of an FID (1981) (10)
- Conformations of 3,5-dichloroanisole and 3,5-dibromoacetophenone determined from 1H nuclear magnetic resonance spectra of nematic solutions (1976) (10)
- Assignment of the 750 MHz 1H NMR resonances from a mixture of transacylated ester glucuronic acid conjugates with the aid of oversampling and digital filtering during acquisition. (1995) (10)
- Low Volume in Vitro Diagnostic Proton NMR Spectroscopy of Human Blood Plasma for Lipoprotein and Metabolite Analysis: Application to SARS-CoV-2 Biomarkers (2021) (10)
- Improvement in the characterization of minor drug metabolites from HPLC-NMR studies through the use of quantified maximum entropy processing of NMR spectra. (1994) (10)
- Symmetry and phase-selected NMR spectra of liquid crystalline samples. (1998) (10)
- 1H NMR Dipolar Relaxation Times and the Derivation of Internuclear Distance (1996) (9)
- The molecular structure and reorientation of parafluorobenzaldehyde dissolved in a smectic mesophase studied using N.M.R. spectroscopy (1977) (9)
- High resolution proton nuclear magnetic resonance studies of interaction between deoxyhaemoglobin and small molecules. Dithionite and diphosphoglycerate (1979) (9)
- Probing molecular dynamics in chromatographic systems using high-resolution 1H magic-angle-spinning NMR spectroscopy: interaction between p-Xylene and C18-bonded silica. (2004) (9)
- 2.7.5. HPLC/NMR and related hyphenated NMR methods (2000) (9)
- Urinary metabolites of 2-bromoethanamine identified by stable isotope labelling: evidence for carbamoylation and glutathione conjugation (2011) (9)
- Application of the FLIPSY pulse sequence for increased sensitivity in 1H NMR-based metabolic profiling studies. (2008) (9)
- Biofluids Studied By NMR (1999) (8)
- Structure of pentafluorobenzaldehyde determined from nuclear magnetic resonance spectra of nematic solutions (1976) (8)
- An NMR study of the conformational flexibility of phenyl acetate dissolved in a nematic liquid crystalline solvent (1995) (8)
- Orientation studies by N.M.R. spectroscopy using a lyotropic liquid crystal solvent (1971) (8)
- Structures of some fluorinated pyridines from the analysis of NMR spectra of nematic solutions (1976) (8)
- Measurement of inter‐proton distances from cross‐relaxation rates determined by a selective null inversion–recovery NMR method (1992) (7)
- Encyclopedia of Spectroscopy and Spectrometry, 2nd Edition (2010) (7)
- A multinuclear magnetic resonance study of protonation in imidazo[1,2‐a]pyrazine (1990) (7)
- Observation of Separate J-Resolved 1H-NMR Spectra from CH, CH2, and CH3 Groups Using a Maximum-Quantum Filter (1995) (7)
- Quantitative structure―chromatography relationships : prediction of TLC behavior using theoretically derived molecular properties (1991) (7)
- Encyclopedia of Spectroscopy and Spectrometry, 2nd Edition (2010) (7)
- Determination of the tautomeric equilibria of pyridoyl benzoyl β-diketones in the liquid and solid state through the use of deuterium isotope effects on (1)H and (13)C NMR chemical shifts and spin coupling constants. (2015) (7)
- An Overview of Metabolic Phenotyping and Its Role in Systems Biology (2019) (7)
- Assignment of the 1H, 19F, and 13C NMR spectra of 2-deoxy-2-fluoro-d-ribose and characterisation of the isomeric equilibrium (1996) (7)
- Nuclear magnetic double and triple resonance studies on pentafluoropyridine (1972) (7)
- An Overview of Metabonomics Techniques and Applications (2010) (7)
- Simplification of the 1H nuclear magnetic resonance spectra of partially oriented molecules by partial deuteriation and deuterium decoupling (1971) (7)
- Structures of 1,3,5-trichloro- and 1,3,5-trichlorotrifluorobenzene derived from n.m.r. spectra of nematic solutions (1976) (7)
- 19F NMR spectroscopic investigation into the absorption and metabolism of 3-trifluoromethylaniline in Eisenia veneta. (2003) (7)
- Quantitative Investigation of Probabilistic Spectral Processing Methods Using Simulated NMR Data (2001) (6)
- Raised transaminase activity of blood plasma from rats with experimentally-induced kidney damage detected by spin-echo 1H-NMR spectroscopy. (1993) (6)
- 19F NMR Spectroscopy: Applications in Pharmaceutical Studies (2015) (6)
- Standardized Protocols for MS-Based Metabolic Phenotyping (2017) (6)
- The Development of Metabolic Phenotyping—A Historical Perspective (2016) (6)
- The 1H N.M.R. spectrum of cyclopentadiene dissolved in a nematic liquid crystal (1974) (6)
- Continuous bond rotation models for the conformational analysis of the methoxy groups in 1,2-dimethoxy- and 1,2,3-trimethoxy-benzene using dipolar couplings obtained from the NMR spectra of oriented samples in nematic liquid crystalline solutions (1998) (6)
- Magnetic resonance imaging in a model of atherosclerosis: use of a collar around the rabbit carotid artery. (1991) (6)
- Purification, characterization and immunological properties of the serotype-specific capsular polysaccharide of Pasteurella haemolytica (serotype T4) organisms. (1985) (6)
- High‐resolution 1H NMR spectroscopic investigation of a chick embryo model of neural tube development (2009) (6)
- 19F nuclear magnetic resonance spectrum of pentafluoropyridine partially oriented in a nematic phase. (1972) (6)
- Biomedical and Pharmaceutical Applications of HPLC–NMR and HPLC–NMR–MS (2003) (6)
- Anti-tumour Effects of 5-hydroxytryptamine (5-HT) are Not Entirely Attributable to Its Effects on Tumour Vasculature (1991) (6)
- Evidence for an anisotropic contribution to 3 J FF from the 19F N.M.R. spectrum of hexafluorocyclopropane dissolved in a nematic phase (1975) (6)
- Development of quantitative structure-metabolism (QSMR) relationships for substituted anilines based on computational chemistry (2013) (6)
- An investigation of solid-state phase transitions in 1- and 2-adamantanol by 13C CP-MAS NMR (1991) (6)
- 1H and 13C NMR studies of the protonation of isomeric methoxysulmazole analogues (1990) (6)
- Proton, carbon-13 and proton-(deuterium) INDOR n.m.r. spectra of isotopically labelled acetaldehyde dissolved in a nematic phase (1975) (6)
- Automatic Recognition of Multiplet Patterns and Measurement of Coupling Constants in NMR and EPR Spectra through the Application of Maximum-Entropy Deconvolution (1996) (6)
- Liquid chromatography directly and jointly combined with nuclear magnetic resonance spectroscopy and mass spectrometry (1998) (5)
- J-Edited DIffusional Proton Nuclear Magnetic Resonance Spectroscopic Measurement of Glycoprotein and Supramolecular Phospholipid Biomarkers of Inflammation in Human Serum. (2022) (5)
- Structural investigation of the η-allyl group in (η-allyl)tetracarbonylrhenium by nematic-phase nuclear magnetic resonance spectroscopy (1975) (5)
- Purification, characterization and immunological properties of the serotype-specific capsular polysaccharide of Pasteurella haemolytica serotype A7 organisms. (1986) (5)
- Structure of 2,3,5,6-tetrafluoroanisole determined from the analysis of a nuclear magnetic resonance spectrum of a nematic solution (1976) (5)
- The -Omics in Drug Development (2011) (4)
- Studies on the effects ofl(αS,5S)-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) on 4-aminophenol-induced nephrotoxicity in the Fischer 344 rat (2005) (4)
- Biofluids Studied by NMR Spectroscopy (2010) (4)
- Chapter 15 – A Survey of Metabonomics Approaches for Disease Characterisation (2007) (4)
- Quantitative structure-toxicity relationships for chlorophenols to bioluminescent lux-marked bacteria using atom-based semi-empirical molecular-orbital descriptors. (1999) (4)
- Overview of NMR-Based Metabonomics (2010) (4)
- The Role of Nuclear Magnetic Resonance Spectroscopy in Drug Metabolism (1999) (4)
- Studies on the effects of L(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) on 4-aminophenol-induced nephrotoxicity in the Fischer 344 rat. (1993) (4)
- Exploration of Human Serum Lipoprotein Supramolecular Phospholipids Using Statistical Heterospectroscopy in n-Dimensions (SHY-n): Identification of Potential Cardiovascular Risk Biomarkers Related to SARS-CoV-2 Infection. (2022) (4)
- Can metabolic profiling provide a new description of osteoarthritis and enable a personalised medicine approach? (2020) (4)
- Recent advances in editing and selective detection methods for H-1 NMR spectroscopy (2001) (4)
- Semiempirical Molecular-Orbital Properties of Some Polycyclic Aromatic Hydrocarbons and Correlation with Environmental Toxic Equivalency Factors (2003) (4)
- Improved Spatial Resolution of Metabolites in Tissue Biopsies Using High-Resolution Magic-Angle-Spinning Slice Localization NMR Spectroscopy. (2020) (4)
- Comparison of Maximum Quantum Filtered NMR Spectroscopy (MAXY NMR) and Other Two‐Dimensional NMR Approaches for Resonance Assignment of Peptides (1996) (4)
- Multicentre quantitative data-analysis trial: the overlapping background problem. (1996) (3)
- Response to Comment on “Optimized Preprocessing of Ultra-Performance Liquid Chromatography/Mass Spectrometry Urinary Metabolic Profiles for Improved Information Recovery” (2011) (3)
- Investigation of water environments in a C18 bonded silica phase using 1H magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy. (2001) (3)
- Pharmacometabonomics and Predictive Metabonomics: New Tools for Personalized Medicine (2016) (3)
- The influence of sample collection, handling and low temperature storage upon NMR metabolic profiling analysis in human synovial fluid. (2021) (3)
- Studies of tautomerism and protonation in 2‐aryl‐1H‐imidazo[1,2‐a]imidazole derivatives using 1H and 13C NMR (1991) (3)
- A comparison of human serum and plasma metabolites using untargeted 1H NMR spectroscopy and UPLC-MS (2018) (3)
- Application of Resolution Enhancement in FT NMR to the Structural Determination of Deoxy Sugars (1980) (3)
- The N.M.R. spectrum of tropolone dissolved in nematic solvents. An exchanging spin system (1974) (3)
- Basic one‐ and two‐dimensional NMR spectroscopy, 3rd edn, by Horst Friebolin. Wiley‐VCH, Weinheim, 1998. Pages: 386 + xxiv. Price: £24.95 (paperback). ISBN 3 527 29513 5 (1999) (3)
- Assessment of NMR probe temperature stability and gradient using a nematic phase solution (1994) (3)
- An investigation into the molecular structure of tropone, from its proton N.M.R. spectrum in a nematic solvent (1973) (3)
- NMR and MS urinary metabolic phenotyping in kidney diseases is fit-for-purpose in the presence of a protease inhibitor. (2019) (3)
- 1H, 13C and 15N NMR Studies of Protonation in Imidazo[1,2-α]Pyrimidine and Derivatives (1991) (3)
- Peer Reviewed: Advancing Hyphenated Chromatographic Systems. (2000) (3)
- Geology and Mineralogy, Applications of Atomic Spectroscopy (1999) (3)
- Kinetic modelling of acyl glucuronide and glucoside reactivity and development of structure-property relationships. (2020) (2)
- Intramolecular acetalisation of naphthoquinones (1982) (2)
- Conception, Implementation and Operation of Large-Scale Metabolic Phenotyping Centres: Phenome Centres (2019) (2)
- Recent Developments and Applications of NMR-Based Metabonomics (2006) (2)
- NMR-based Metabolic Phenotyping Techniques and Applications (2017) (2)
- Observation of solid-state phase changes in adamantanols using 13C CP-MAS NMR (1994) (2)
- Molecular Flexibility of N-Acyl Heterocycles Studied Using 1 3C NMR Spectroscopy and Computational Chemistry (1998) (2)
- Solid state 13C NMR and phase transitions in hydroxyadamantanes (1989) (2)
- An Overview of Metabonomics (2005) (2)
- NMR Spectroscopy of Biofluids, Tissues, and Tissue Extracts (2008) (2)
- Acyl Glucuronides: Biological Activity, Chemical Reactivity, and Chemical Synthesis (2007) (2)
- NMR spectroscopy: analytical applications from chemistry to the clinic. (1986) (2)
- Differences between infected and noninfected synovial fluid (2021) (2)
- Structure and conformation of 4-nitrophenyl acetate from proton nuclear magnetic resonance of nematic solutions (1977) (2)
- Introduction to Solid-state NMR spectroscopy, by Melinda J. Duer. Blackwell Science, Oxford, 2004, ISBN 1-4051-0914-9, 349 pp. (2005) (2)
- In Vivo NMR, Methods (1999) (2)
- Chapter 10 Biomedical applications of directly–coupled chromatography—nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) (2003) (2)
- Conformational Flexibility of N-Formylmorpholine Studied Using Variable Temperature 13C NMR Spectroscopy and Molecular Dynamics Calculations (1993) (2)
- Liquid chromatography coupled with high-field proton nuclear magnetic resonance spectroscopy : current status and future prospects (1993) (2)
- 19 F NMR Spectroscopy (2013) (1)
- Anti-tumor effects of 5-hydroxytryptamine (5-HT) are not entirely attributable to its effects on tumor vasculature. (1991) (1)
- SPECT, Methods and Instrumentation (2010) (1)
- NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | Instrumentation (2005) (1)
- Characterisation of the conformational and tautomeric properties of benzylamino derivatives of 1,4-diphenyl-2-butene-1,4-dione using NMR spectroscopy (1997) (1)
- Abstract MP09: Untargeted 1 H Nmr Metabolomics Metabolomic Analysis Reveals Pathways Of Protection Between Mediterranean-style Diet And Incident Cardiovascular Disease In The Multi-ethnic Study Of Atherosclerosis. (2021) (1)
- NMR in pharmaceutical sciences (2015) (1)
- Future Visions for Clinical Metabolic Phenotyping: Prospects and Challenges (2016) (1)
- Mixture Analysis in Pharmaceutical R&D Using Hyphenated NMR Techniques (2015) (1)
- NMR-based Metabonomics Techniques and Applications (2008) (1)
- Research Associate Full report (2011) (1)
- Chapter 19 – Global Systems Biology Through Integration of “Omics” Results (2007) (1)
- Metabonomics: NMR Techniques (2008) (1)
- An Investigation of Protonation in 2-Methoxy Pyrazine Using 13C AND 15N NMR Spectroscopy (1991) (1)
- The 1H nuclear magnetic resonance spectra of 6-substituted bicyclo[3.1.0] hex-2-enes (1982) (1)
- Chapter 6 – NMR spectra from quadrupolar nuclei (1975) (1)
- Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy (Analytical Chemistry (2007) 79 (2629-2640)) (2008) (1)
- The Metabolic Window into Systems Biology (2007) (1)
- 1H, 13C and 31P n.m.r. spectra and molecular conformation of myo-inositol 1,4,5-trisphosphate (2005) (1)
- Spatially Resolved IR (2017) (1)
- Conclusions from NMR on the preferred direction of attack during quaternisation of 1-benzyl-tetrahydroisoquinolines (1980) (1)
- Metabolic Phenotyping: History, Status, and Prospects (2019) (1)
- 1869: Nuclear Magnetic Resonance Based Metabonomic Investigation of Semen, Urine and Plasma Metabolite Profiles in Healthy Volunteers and Men with Spinal Cord Injury (2007) (1)
- Atomic Spectroscopy, Electronic Components Applications (2017) (0)
- NMR and pattern recognition studies on the biochemistry of black tea-derived polyphenolic compounds in the rat. (2001) (0)
- Improving visualisation and interpretation of metabolome-wide association studies (MWAS): an application in a population based cohort using untargeted 1H (2017) (0)
- Preface to 2nd Edition (2010) (0)
- Proton NMR Relaxation Times and Trace Paramagnetic Metal Contents: Pattern Recognition Analysis of the Discrimination Between Normal and Pathological Tissue of the Gastrointestinal Tract and Bone Marrow (1990) (0)
- Electronic Components, Applications of Atomic Spectroscopy (1999) (0)
- Improvement of FT NMR sensitivity on a spectrometer normally using a double-tuned receiver coil (1980) (0)
- Multidimensional NMR Spectroscopy (2013) (0)
- Chapter 9 – Rotation of nematic samples (1975) (0)
- Preface to 1st Edition (2010) (0)
- NMR spectroscopy and pattern recognition methods. Novel findings associated with alterations in nicotinic acid metabolism within autistic individuals showing increased urinary excretion of N-methyl-2-pyridone-5- carboxamide, N-methyl nicotinic acid and N-methyl nicotinamide, indicate a perturbation (2015) (0)
- OP-EHEA190237_online 2883..2898 (2019) (0)
- THE PROTON NUCLEAR MAGNETIC RESONANCE SPECTRA OF 6-SUBSTITUTED BICYCLO(3.1.0)HEX-2-ENES (1982) (0)
- Book reviews (1998) (0)
- Identifying unknown metabolites using NMR-based metabolic profiling techniques (2020) (0)
- Book reviews (2001) (0)
- NMR — from chemistry to medicine (1983) (0)
- Nucleic Acids Studied Using NMR (1999) (0)
- STRUCTURAL INVESTIGATION OF THE ETA-ALLYL GROUP IN (ETA-ALLYL)TETRACARBONYLRHENIUM BY NEMATIC-PHASE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (1975) (0)
- Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series (2016) (0)
- Evaluation of high resolution magic-angle coil spinning NMR ( HR-MACS-NMR ) spectroscopy for metabolic profiling of nanoliter tissue biopsies (2015) (0)
- An Adventitious Synthesis of a 5-Methylimidazo(4,5-c)pyridine Derivative. (1987) (0)
- NMR-Based Metabolic Phenotyping: An Overview ☆ (2018) (0)
- Chapter 10 – Nuclear magnetic double resonance (1975) (0)
- Cephaloridine-induced nephrotoxicity in the fischer 344 rat proton NMR spectroscopic studies of urine and plasma in relation to conventional clinical chemical and histopathological assessments of nephronal damage (1993) (0)
- The Small Molecule Components of Human Synovial Fluid and Bovine Calf Serum that Correlate with Cobalt Chrome (CoCrMo) Wear (2021) (0)
- Analysis of the effect of solvent on the tautomeric equilibrium in naphthaldehyde schiff bases using multivariate statistics and pattern recognition (1994) (0)
- NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY TECHNIQUES | Multidimensional Proton (2005) (0)
- Application of novel solid phase extraction-NMR protocols for metabolic profiling of human urine. (2019) (0)
- Chapter 5 – Studies of internal motion (1975) (0)
- The conformational behaviour of the cardiac glycoside digoxin as indicated by NMR spectroscopy and molecular dynamics calculations. (1992) (0)
- The effect of liquid-liquid extraction on metabolite detection and analysis using NMR spectroscopy in human synovial fluid. (2023) (0)
- INTRAMOLECULAR ACETALIZATION OF NAPHTHOQUINONES (1982) (0)
- Chapter 4 – Determination of the structure of rigid molecules (1975) (0)
- G. A. Webb (editor). Annual reports on NMR spectroscopy, vol. 23. Academic Press, London, 1991, pp. 425, £65.00 (1991) (0)
- ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY (UPLC) COUPLED WITH TIME OF FLIGHT MASS SPECTROMETRY FOR COMPLEX MULTI-COMPONENT ANALYSES (2004) (0)
- Measurement of longitudinal relaxation times in crowded 1H NMR spectra using one- and two-dimensional maximum quantum (MAXY) NMR spectroscopy (2001) (0)
- Lindon, John C.: Excursions in NMR from Molecules to Man (2010) (0)
- Chapter 7 – Anisotropy in nuclear spin-spin coupling (1975) (0)
- Chapter 3 – Analysis of NMR spectra of partially oriented molecules (1975) (0)
- NMR Spectroscopy of Nucleic Acids, Historical Overview (2017) (0)
- NMR Parameter Survey, 13 C (2017) (0)
- 13 C NMR, Parameter Survey (1999) (0)
- NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY-APPLICABLE ELEMENTS | Fluorine-19 (2005) (0)
- K. Kamienska-Trela (Ed.): Nuclear Magnetic Resonance. Volume 40. Specialist Periodical Reports of the Royal Society of Chemistry (2012) (0)
- Abstract 17379: Untargeted Metabolomic Analyses Reveal Mechanistic Links Between a Mediterranean-Style Diet and Incident Cardiovascular Disease in the Multi-Ethnic Study of Atherosclerosis (2017) (0)
- Peter Bigler NMR Spectroscopy: Processing Strategies, 2nd edn Wiley‐VCH, Weinheim, 1999, pp xi + 253 plus CD‐ROM, £95.00. (2000) (0)
- The Development of a Metabonomic‐Based Drug Safety Testing Paradigm (2008) (0)
- Chapter 8 – Anisotropy in chemical shifts (1975) (0)
- Recent Advances in Editing and Selective Detection Methods for 1H NMR Spectroscopy (2001) (0)
- Forensic Science, Applications of Atomic Spectroscopy (1999) (0)
- Optimization of Diffusion-Ordered NMR Spectroscopy Experiments for High-Throughput Automation in Human Metabolic Phenotyping (2023) (0)
- 1H Magic Angle Spinning NMR Spectroscopy of Tissues (2005) (0)
- Chapter 2 – The nuclear spin Hamiltonian for partially oriented molecules (1975) (0)
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What Schools Are Affiliated With John Christopher Lindon?
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