John D. Salamone
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Engineering Computer Science
John D. Salamone's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Computer Engineering University of California, Berkeley
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(Suggest an Edit or Addition)John D. Salamone's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Mysterious Motivational Functions of Mesolimbic Dopamine (2012) (1088)
- Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits (2007) (956)
- Motivational views of reinforcement: implications for understanding the behavioral functions of nucleus accumbens dopamine (2002) (802)
- The involvement of nucleus accumbens dopamine in appetitive and aversive motivation (1994) (587)
- Behavioral functions of nucleus accumbens dopamine: Empirical and conceptual problems with the anhedonia hypothesis (1997) (525)
- Beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine. (2005) (471)
- Anhedonia or anergia? Effects of haloperidol and nucleus accumbens dopamine depletion on instrumental response selection in a T-maze cost/benefit procedure (1994) (450)
- Nucleus Accumbens Dopamine and the Regulation of Effort in Food-Seeking Behavior: Implications for Studies of Natural Motivation, Psychiatry, and Drug Abuse (2003) (421)
- Neurobiology of Exercise (2006) (421)
- Haloperidol and nucleus accumbens dopamine depletion suppress lever pressing for food but increase free food consumption in a novel food choice procedure (2005) (329)
- Place navigation in rats is impaired by lesions of medial septum and diagonal band but not nucleus basalis magnocellularis (1988) (290)
- Dopamine, Behavioral Economics, and Effort (2009) (260)
- Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology. (2016) (245)
- Nucleus accumbens dopamine depletions make rats more sensitive to high ratio requirements but do not impair primary food reinforcement (1999) (244)
- Nucleus accumbens dopamine depletions alter relative response allocation in a T-maze cost/benefit task (1996) (228)
- D1 or D2 antagonism in nucleus accumbens core or dorsomedial shell suppresses lever pressing for food but leads to compensatory increases in chow consumption (2001) (216)
- Lesions in Medial Preoptic Area and Bed Nucleus of Stria Terminalis: Differential Effects on Copulatory Behavior and Noncontact Erection in Male Rats (1997) (210)
- Nucleus accumbens dopamine release increases during instrumental lever pressing for food but not free food consumption (1994) (205)
- Nucleus accumbens dopamine depletions make animals highly sensitive to high fixed ratio requirements but do not impair primary food reinforcement (2001) (199)
- Effects of Dopamine Antagonists and Accumbens Dopamine Depletions on Time-Constrained Progressive-Ratio Performance (1998) (186)
- Ventrolateral striatal dopamine depletions impair feeding and food handling in rats (1993) (180)
- Nucleus accumbens dopamine depletions in rats affect relative response allocation in a novel cost/benefit procedure (1994) (177)
- A neurochemical and behavioral investigation of the involvement of nucleus accumbens dopamine in instrumental avoidance (1993) (176)
- Different effects of nucleus accumbens and ventrolateral striatal dopamine depletions on instrumental response selection in the rat (1993) (174)
- Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences (2012) (173)
- The behavioral neurochemistry of motivation: methodological and conceptual issues in studies of the dynamic activity of nucleus accumbens dopamine (1996) (171)
- The Role of Accumbens Dopamine in Lever Pressing and Response Allocation: Effects of 6-OHDA Injected into Core and Dorsomedial Shell (1998) (170)
- The cannabinoid CB1 antagonists SR 141716A and AM 251 suppress food intake and food-reinforced behavior in a variety of tasks in rats (2003) (167)
- Involvement of nucleus accumbens dopamine in the motor activity induced by periodic food presentation: a microdialysis and behavioral study (1992) (165)
- The behavioral pharmacology of effort-related choice behavior: dopamine, adenosine and beyond. (2012) (159)
- Tremulous jaw movements in rats:a model of parkinsonian tremor (1998) (155)
- Complex motor and sensorimotor functions of striatal and accumbens dopamine: involvement in instrumental behavior processes (2005) (154)
- Effects of dopamine depletions in the medial prefrontal cortex on DRL performance and motor activity in the rat (1994) (146)
- Dopaminergic involvement in activational aspects of motivation: Effects of haloperidol on schedule-induced activity, feeding, and foraging in rats (1988) (145)
- The role of brain dopamine in response initiation: effects of haloperidol and regionally specific dopamine depletions on the local rate of instrumental responding (1993) (145)
- Dopamine antagonists alter response allocation but do not suppress appetite for food in rats: contrast between the effects of SKF 83566, raclopride, and fenfluramine on a concurrent choice task (2002) (143)
- Mesolimbic Dopamine and the Regulation of Motivated Behavior. (2015) (142)
- The Novel Cannabinoid CB1 Receptor Neutral Antagonist AM4113 Suppresses Food Intake and Food-Reinforced Behavior but Does not Induce Signs of Nausea in Rats (2008) (138)
- Nucleus accumbens dopamine and work requirements on interval schedules (2002) (134)
- Cannabinoid CB1 receptor inverse agonists and neutral antagonists: Effects on food intake, food-reinforced behavior and food aversions (2007) (133)
- The adenosine A2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism (2004) (128)
- Nucleus Accumbens Adenosine A2A Receptors Regulate Exertion of Effort by Acting on the Ventral Striatopallidal Pathway (2008) (124)
- Pharmacological characterization of performance on a concurrent lever pressing/feeding choice procedure: effects of dopamine antagonist, cholinomimetic, sedative and stimulant drugs (1994) (119)
- Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: Effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors (2013) (119)
- Accumbens dopamine and the regulation of effort in food-seeking behavior: modulation of work output by different ratio or force requirements (2004) (119)
- Adenosine A2A receptor antagonism and genetic deletion attenuate the effects of dopamine D2 antagonism on effort-based decision making in mice (2012) (118)
- Impairment in T-maze reinforced alternation performance following nucleus basalis magnocellularis lesions in rats (1984) (116)
- Effort-Related Motivational Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Animal Models of the Motivational Symptoms of Depression (2013) (114)
- Nucleus accumbens and effort-related functions: behavioral and neural markers of the interactions between adenosine A2A and dopamine D2 receptors (2010) (113)
- The role of nucleus accumbens dopamine in the neurochemical and behavioral effects of phencyclidine: a microdialysis and behavioral study (1993) (113)
- Nucleus Accumbens Dopamine and the Forebrain Circuitry Involved in Behavioral Activation and Effort-Related Decision Making: Implications for Understanding Anergia and Psychomotor Slowing in Depression (2006) (108)
- The adenosine A2A antagonist MSX-3 reverses the effects of the dopamine antagonist haloperidol on effort-related decision making in a T-maze cost/benefit procedure (2009) (107)
- Piecing together the puzzle of acetaldehyde as a neuroactive agent (2012) (105)
- A microdialysis study of nucleus accumbens core and shell dopamine during operant responding in the rat (1998) (105)
- Characterization of the impaired feeding behavior in rats given haloperidol or dopamine-depleting brain lesions (1990) (103)
- Ratio and time requirements on operant schedules: effort‐related effects of nucleus accumbens dopamine depletions (2005) (103)
- Cannabinoid CB1 antagonists and dopamine antagonists produce different effects on a task involving response allocation and effort-related choice in food-seeking behavior (2008) (103)
- Differential actions of adenosine A1 and A2A antagonists on the effort-related effects of dopamine D2 antagonism (2009) (102)
- Intra-accumbens injections of the adenosine A2A agonist CGS 21680 affect effort-related choice behavior in rats (2008) (100)
- The role of nucleus accumbens dopamine in responding on a continuous reinforcement operant schedule: A neurochemical and behavioral study (1993) (98)
- Open field locomotor effects in rats after intraventricular injections of ethanol and the ethanol metabolites acetaldehyde and acetate (2003) (98)
- Adenosine A2A receptor antagonism reverses the effects of dopamine receptor antagonism on instrumental output and effort-related choice in the rat: implications for studies of psychomotor slowing (2007) (97)
- Forebrain circuitry involved in effort-related choice: Injections of the GABAA agonist muscimol into ventral pallidum alter response allocation in food-seeking behavior (2008) (96)
- Involvement of ventrolateral striatal dopamine in movement initiation and execution: A microdialysis and behavioral investigation (1996) (95)
- The pharmacology of effort-related choice behavior: Dopamine, depression, and individual differences (2016) (92)
- Sexual Behavior in Male Rats After Radiofrequency or Dopamine-Depleting Lesions in Nucleus Accumbens (1998) (91)
- Nucleus Accumbens Dopamine Depletions and Time-Constrained Progressive Ratio Performance Effects of Different Ratio Requirements (1999) (90)
- Tremorolytic effects of adenosine A2A antagonists: implications for parkinsonism. (2008) (89)
- Impaired sexual response after lesions of the paraventricular nucleus of the hypothalamus in male rats. (1997) (88)
- Increases in extracellular dopamine levels and locomotor activity after direct infusion of phencyclidine into the nucleus accumbens (1992) (88)
- Effort-related motivational effects of the pro-inflammatory cytokine interleukin 1-beta: studies with the concurrent fixed ratio 5/ chow feeding choice task (2014) (86)
- The VMAT-2 Inhibitor Tetrabenazine Affects Effort-Related Decision Making in a Progressive Ratio/Chow Feeding Choice Task: Reversal with Antidepressant Drugs (2014) (86)
- The cannabinoid CB1 antagonist AM 251 produces food avoidance and behaviors associated with nausea but does not impair feeding efficiency in rats (2005) (85)
- Brain mechanisms underlying apathy (2018) (85)
- Comparison between multiple behavioral effects of peripheral ethanol administration in rats: sedation, ataxia, and bradykinesia. (2006) (85)
- Measuring reinforcement learning and motivation constructs in experimental animals: Relevance to the negative symptoms of schizophrenia (2013) (84)
- The Actions of Neuroleptic Drugs on Appetitive Instrumental Behaviors (1987) (83)
- The effects of haloperidol and clozapine on PCP- and amphetamine-induced suppression of social behavior in the rat (1994) (83)
- Bupropion Increases Selection of High Effort Activity in Rats Tested on a Progressive Ratio/Chow Feeding Choice Procedure: Implications for Treatment of Effort-Related Motivational Symptoms (2015) (82)
- The VMAT-2 inhibitor tetrabenazine alters effort-related decision making as measured by the T-maze barrier choice task: reversal with the adenosine A2A antagonist MSX-3 and the catecholamine uptake blocker bupropion (2015) (81)
- The adenosine A2A antagonist MSX-3 reverses the effort-related effects of dopamine blockade: differential interaction with D1 and D2 family antagonists (2009) (80)
- Differential effects of selective adenosine antagonists on the effort-related impairments induced by dopamine D1 and D2 antagonism (2010) (80)
- Dopamine, Effort-Based Choice, and Behavioral Economics: Basic and Translational Research (2018) (80)
- Potential anxiogenic effects of cannabinoid CB1 receptor antagonists/inverse agonists in rats: Comparisons between AM4113, AM251, and the benzodiazepine inverse agonist FG-7142 (2010) (78)
- The effects of nucleus accumbens dopamine depletions on continuously reinforced operant responding: Contrasts with the effects of extinction (1995) (78)
- Dopamine and Food Addiction: Lexicon Badly Needed (2013) (77)
- Vacuous jaw movements induced by acute reserpine and low-dose apomorphine: Possible model of parkinsonian tremor (1996) (76)
- Tremulous jaw movements induced by the acetylcholinesterase inhibitor tacrine: effects of antiparkinsonian drugs. (1997) (76)
- Nucleus accumbens dopamine and rate of responding: Neurochemical and behavioral studies (1999) (75)
- Dopamine/adenosine interactions related to locomotion and tremor in animal models: possible relevance to parkinsonism. (2008) (74)
- Different behavioral effects of haloperidol, clozapine and thioridazine in a concurrent lever pressing and feeding procedure (1996) (74)
- A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model (2008) (73)
- Tremulous Jaw Movements Produced by Acute Tacrine Administration: Possible Relation to Parkinsonian Side Effects (1997) (73)
- The role of dopamine D1 receptor transmission in effort-related choice behavior: Effects of D1 agonists (2015) (72)
- Transplantation of embryonic ventral forebrain grafts to the neocortex of rats with bilateral lesions of nucleus basalis magnocellularis ameliorates a lesion-induced deficit in spatial memory (1988) (71)
- Substantia nigra pars reticulata is a highly potent site of action for the behavioral effects of the D1 antagonist SCH 23390 in the rat (2001) (70)
- Interactions between dopamine D1 receptors and γ-aminobutyric acid mechanisms in substantia nigra pars reticulata of the rat: neurochemical and behavioral studies (2001) (70)
- Neurobiological basis of motivational deficits in psychopathology (2015) (69)
- Functions of mesolimbic dopamine: changing concepts and shifting paradigms (2007) (69)
- The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior (2010) (69)
- Different behavioral functions of dopamine in the nucleus accumbens and ventrolateral striatum: a microdialysis and behavioral investigation (1999) (66)
- Tremulous Characteristics of the Vacuous Jaw Movements Induced by Pilocarpine and Ventrolateral Striatal Dopamine Depletions (1997) (66)
- Temporal Measures of Human Finger Tapping: Effects of Age (1998) (66)
- Dopamine/adenosine interactions involved in effort-related aspects of food motivation (2009) (64)
- Paradoxical kinesia in parkinsonism is not caused by dopamine release. Studies in an animal model. (1989) (63)
- The Psychopharmacology of Effort-Related Decision Making: Dopamine, Adenosine, and Insights into the Neurochemistry of Motivation (2018) (63)
- The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors (2007) (62)
- The role of acetaldehyde in the central effects of ethanol. (2005) (62)
- Caffeine and Selective Adenosine Receptor Antagonists as New Therapeutic Tools for the Motivational Symptoms of Depression (2018) (61)
- Anxiogenic drugs beta-CCE and FG 7142 increase extracellular dopamine levels in nucleus accumbens (2005) (61)
- Rats with partial striatal dopamine depletions exhibit robust and long-lasting behavioral deficits in a simple fixed-ratio bar-pressing task (1997) (60)
- Blockade of uptake for dopamine, but not norepinephrine or 5-HT, increases selection of high effort instrumental activity: Implications for treatment of effort-related motivational symptoms in psychopathology (2016) (59)
- Not All Antidepressants Are Created Equal: Differential Effects of Monoamine Uptake Inhibitors on Effort-Related Choice Behavior (2016) (58)
- Effects of lisdexamfetamine and s-citalopram, alone and in combination, on effort-related choice behavior in the rat (2016) (57)
- Effort-related motivational effects of the pro-inflammatory cytokine interleukin-6: pharmacological and neurochemical characterization (2016) (56)
- Motor Stimulant Effects of Ethanol Injected into the Substantia Nigra Pars Reticulata: Importance of Catalase-Mediated Metabolism and the Role of Acetaldehyde (2006) (55)
- Lateral striatal cholinergic mechanisms involved in oral motor activities in the rat (2005) (54)
- Different effects of haloperidol and extinction on instrumental behaviours (2004) (54)
- Injections of the selective adenosine A2A antagonist MSX-3 into the nucleus accumbens core attenuate the locomotor suppression induced by haloperidol in rats (2007) (53)
- Effects of the adenosine A2A antagonist KW 6002 (istradefylline) on pimozide-induced oral tremor and striatal c-Fos expression: comparisons with the muscarinic antagonist tropicamide (2009) (53)
- Stimulant effects of adenosine antagonists on operant behavior: differential actions of selective A2A and A1 antagonists (2011) (53)
- Neostriatal muscarinic receptor subtypes involved in the generation of tremulous jaw movements in rodents implications for cholinergic involvement in parkinsonism. (2001) (53)
- Selection of sucrose concentration depends on the effort required to obtain it: studies using tetrabenazine, D1, D2, and D3 receptor antagonists (2015) (52)
- Vacuous jaw movements in rats induced by acute reserpine administration: Interactions with different doses of apomorphine (1993) (52)
- Interactions between adenosine and dopamine receptor antagonists with different selectivity profiles: Effects on locomotor activity (2010) (51)
- Midbrain Dopamine Neurons Associated with Reward Processing Innervate the Neurogenic Subventricular Zone (2011) (50)
- Behavioural and pharmacological characterization of the mouth movements induced by muscarinic agonists in the rat (2004) (50)
- Choosing voluntary exercise over sucrose consumption depends upon dopamine transmission: effects of haloperidol in wild type and adenosine A2AKO mice (2016) (50)
- Behavioral activation in rats increases striatal dopamine metabolism measured by dialysis perfusion (1989) (48)
- Behavioral effects of intraventricular injections of low doses of ethanol, acetaldehyde, and acetate in rats: studies with low and high rate operant schedules (2003) (47)
- Skilled motor deficits in rats induced by ventrolateral striatal dopamine depletions: behavioral and pharmacological characterization (1996) (47)
- Effects of acute haloperidol and reserpine administration on vacuous jaw movements in three different age groups of rats (1993) (47)
- Locomotor stimulant effects of intraventricular injections of low doses of ethanol in rats: acute and repeated administration (2003) (47)
- A detailed characterization of the effects of four cannabinoid agonists on operant lever pressing (1998) (47)
- The CB1 inverse agonist AM251, but not the CB1 antagonist AM4113, enhances retention of contextual fear conditioning in rats (2010) (46)
- Preladenant, a novel adenosine A(2A) receptor antagonist for the potential treatment of parkinsonism and other disorders. (2010) (45)
- Dopamine agonists suppress cholinomimetic-induced tremulous jaw movements in an animal model of Parkinsonism: tremorolytic effects of pergolide, ropinirole and CY 208–243 (2005) (44)
- The novel adenosine A2A antagonist prodrug MSX-4 is effective in animal models related to motivational and motor functions (2012) (44)
- In vitro generation of dopaminergic neurons from adult subventricular zone neural progenitor cells. (2008) (43)
- Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. (1999) (42)
- Slow phasic changes in nucleus accumbens dopamine release during fixed ratio acquisition: a microdialysis study (2011) (41)
- Vacuous jaw movements induced by sub-chronic administration of haloperidol: interactions with scopolamine (2005) (41)
- Effects of clozapine, thioridazine, risperidone and haloperidol on behavioral tests related to extrapyramidal motor function (1997) (41)
- The Role of Ventrolateral Striatal Acetylcholine in the Production of Tacrine-Induced Jaw Movements (1999) (40)
- Changes in nucleus accumbens and neostriatal c‐Fos and DARPP‐32 immunoreactivity during different stages of food‐reinforced instrumental training (2012) (39)
- Validation of the tremulous jaw movement model for assessment of the motor effects of typical and atypical antipychotics: effects of pimozide (Orap) in rats (2005) (39)
- Pharmacological and Physiological Characterization of the Tremulous Jaw Movement Model of Parkinsonian Tremor: Potential Insights into the Pathophysiology of Tremor (2011) (39)
- Evaluation of the effort-related motivational effects of the novel dopamine uptake inhibitor PRX-14040 (2016) (39)
- Effects of dopamine depletions in the medial prefrontal cortex on active avoidance and escape in the rat (1994) (38)
- Behavioral and Electromyographic Characterization of the Local Frequency of Tacrine-induced Tremulous Jaw Movements (1998) (38)
- The cannabinoid CB1 receptor inverse agonist AM 251 and antagonist AM 4113 produce similar effects on the behavioral satiety sequence in rats (2008) (38)
- Extracellular ascorbic acid increases in striatum following systemic amphetamine (1984) (38)
- Suppression of food intake and food-reinforced behavior produced by the novel CB1 receptor antagonist/inverse agonist AM 1387 (2006) (38)
- Involvement of pallidal and nigral gaba mechanisms in the generation of tremulous jaw movements in rats (1997) (38)
- Stress and chronic illness: The inflammatory pathway. (2017) (38)
- Oral tremor induced by the muscarinic agonist pilocarpine is suppressed by the adenosine A2A antagonists MSX-3 and SCH58261, but not the adenosine A1 antagonist DPCPX (2010) (38)
- Motor Dysfunction Produced by Tacrine Administration in Rats (1997) (37)
- Role of dopamine–adenosine interactions in the brain circuitry regulating effort-related decision making: insights into pathological aspects of motivation (2010) (37)
- Striatal and nigral D1 mechanisms involved in the antiparkinsonian effects of SKF 82958 (APB): studies of tremulous jaw movements in rats (1999) (37)
- Local injections of the 5-hydroxytryptamine antagonist mianserin into substantia nigra pars reticulata block tremulous jaw movements in rats: studies with a putative model of Parkinsonian tremor (2002) (36)
- Behavioral effects of the novel cannabinoid full agonist AM 411 (2005) (36)
- Effects of acute and repeated clozapine injections on cholinomimetic-induced vacuous jaw movements (1996) (35)
- Oral bioavailability of the novel cannabinoid CB1 antagonist AM6527: Effects on food-reinforced behavior and comparisons with AM4113 (2009) (35)
- Systemic administration of the adenosine A2A agonist CGS 21680 induces sedation at doses that suppress lever pressing and food intake (2008) (35)
- Effect of subtype-selective adenosine receptor antagonists on basal or haloperidol-regulated striatal function: Studies of exploratory locomotion and c-Fos immunoreactivity in outbred and A2AR KO mice (2013) (34)
- Oral tremor induced by galantamine in rats: A model of the parkinsonian side effects of cholinomimetics used to treat Alzheimer's disease (2011) (34)
- Commentary: WILL THE LAST PERSON WHO USES THE TERM ‘REWARD’ PLEASE TURN OUT THE LIGHTS? COMMENTS ON PROCESSES RELATED TO REINFORCEMENT, LEARNING, MOTIVATION AND EFFORT (2006) (34)
- Effects of subchronic administration of clozapine, thioridazine and haloperidol on tests related to extrapyramidal motor function in the rat (1998) (34)
- The novel adenosine A2A antagonist Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade (2012) (34)
- The Impact of Caffeine on the Behavioral Effects of Ethanol Related to Abuse and Addiction: A Review of Animal Studies. (2013) (34)
- The GABA uptake inhibitor β-alanine reduces pilocarpine-induced tremor and increases extracellular GABA in substantia nigra pars reticulata as measured by microdialysis (2004) (33)
- Dopamine, effort, and decision making: theoretical comment on Bardgett et al. (2009). (2009) (32)
- New Developments on the Adenosine Mechanisms of the Central Effects of Caffeine and Their Implications for Neuropsychiatric Disorders (2018) (32)
- Adenosine A2A receptor deletion affects social behaviors and anxiety in mice: Involvement of anterior cingulate cortex and amygdala (2017) (31)
- Repeated scopolamine injections sensitize rats to pilocarpine-induced vacuous jaw movements and enhance striatal muscarinic receptor binding (1994) (31)
- Tremorolytic effects of safinamide in animal models of drug-induced parkinsonian tremor (2013) (31)
- Effect of the adenosine A2A receptor antagonist MSX-3 on motivational disruptions of maternal behavior induced by dopamine antagonism in the early postpartum rat (2010) (30)
- Behavioural functions of nucleus basalis magnocellularis and its relationship to dementia (1986) (30)
- Brain implantations of engineered gaba-releasing cells suppress tremor in an animal model of Parkinsonism (2003) (29)
- Synthesis and characterization of all four isomers of the muscarinic agonist 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane]. (1987) (28)
- Conditional neural knockout of the adenosine A2A receptor and pharmacological A2A antagonism reduce pilocarpine-induced tremulous jaw movements: Studies with a mouse model of parkinsonian tremor (2013) (27)
- Motor effects of GABAA antagonism in globus pallidus: studies of locomotion and tremulous jaw movements in rats (2003) (27)
- Acetycholine and choline ion-selective microelectrodes (1983) (26)
- Behavioral Activation, Effort-Based Choice, and Elasticity of Demand for Motivational Stimuli: Basic and Translational Neuroscience Approaches (2017) (25)
- Motor Function and Motivation (2010) (25)
- The vesicular monoamine transporter (VMAT-2) inhibitor tetrabenazine induces tremulous jaw movements in rodents: Implications for pharmacological models of parkinsonian tremor (2013) (24)
- Pharmacological studies of effort-related decision making using mouse touchscreen procedures: effects of dopamine antagonism do not resemble reinforcer devaluation by removal of food restriction (2019) (24)
- Intracerebroventricular administration of cannabinoid CB1 receptor antagonists AM251 and AM4113 fails to alter food-reinforced behavior in rats (2009) (24)
- The Novel Atypical Dopamine Uptake Inhibitor (S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding (2019) (24)
- Ethanol and Caffeine Effects on Social Interaction and Recognition in Mice: Involvement of Adenosine A2A and A1 Receptors (2016) (24)
- Substantia nigra pars reticulata GABA is involved in the regulation of operant lever pressing: pharmacological and microdialysis studies (2003) (23)
- Differences between the nonselective adenosine receptor antagonists caffeine and theophylline in motor and mood effects: Studies using medium to high doses in animal models (2014) (23)
- Central vs. peripheral administration of ethanol, acetaldehyde and acetate in rats: Effects on lever pressing and response initiation (2008) (23)
- Simulation studies of in viva electrochemistry (1980) (22)
- Functional significance of nucleus accumbens dopamine: behavior, pharmacology and neurochemistry (2002) (22)
- Acetate as an active metabolite of ethanol: studies of locomotion, loss of righting reflex, and anxiety in rodents (2013) (22)
- Behavioral assessment of atypical antipsychotics in rats: studies of the effects of olanzapine (Zyprexa) (1999) (20)
- Microcomputer Controlled Multielectrode System for in Vivo Electrochemistry (1980) (20)
- Determination of dopamine, homovanillic acid and 3,4-dihydroxyphenylacetic acid in rat brain striatum by high-performance liquid chromatography with electrochemical detection. (1981) (20)
- Involvement of Nucleus Accumbens Dopamine in Behavioral Activation and Effort-Related Functions (2009) (19)
- Behavioral observation and intracerebral electrochemical recording following administration of amphetamine in rats (1982) (19)
- Deep brain stimulation of the subthalamic nucleus reverses oral tremor in pharmacological models of parkinsonism: interaction with the effects of adenosine A2A antagonism (2013) (19)
- Infusions of acetaldehyde into the arcuate nucleus of the hypothalamus induce motor activity in rats. (2009) (19)
- Effects of H1 Antagonists on Cholinomimetic-Induced Tremulous Jaw Movements Studies of Diphenhydramine, Doxepin, and Mepyramine (2000) (19)
- Behavioral effects of inhibition of cannabinoid metabolism: The amidase inhibitor AM374 enhances the suppression of lever pressing produced by exogenously administered anandamide. (2004) (19)
- The role of dopamine D 1 receptor transmission in effort-related choice behavior : Effects of D 1 agonists O O F (2015) (18)
- Dopamine depletion shifts behavior from activity based reinforcers to more sedentary ones and adenosine receptor antagonism reverses that shift: Relation to ventral striatum DARPP32 phosphorylation patterns (2018) (18)
- Quetiapine (Seroquel) shows a pattern of behavioral effects similar to the atypical antipsychotics clozapine and olanzapine: studies with tremulous jaw movements in rats (2005) (18)
- Effects of striatal injections of 8-bromo-cyclic-AMP on pilocarpine-induced tremulous jaw movements in rats (1999) (17)
- Behavioral effects of the novel potent cannabinoid CB1 agonist AM 4054 (2013) (17)
- An automated electrochemical method for in vivo monitoring of catecholamine release (1980) (17)
- Fluoxetine Administration Exacerbates Oral Tremor and Striatal Dopamine Depletion in a Rodent Pharmacological Model of Parkinsonism (2015) (16)
- Behavioral and dopamine transporter binding properties of the modafinil analog (S, S)-CE-158: reversal of the motivational effects of tetrabenazine and enhancement of progressive ratio responding (2020) (15)
- In‐vitro analysis of Pitx3 in mesodiencephalic dopaminergic neuron maturation (2009) (15)
- Caffeine Modulates Food Intake Depending on the Context That Gives Access to Food: Comparison With Dopamine Depletion (2018) (15)
- The novel cannabinoid agonist AM 411 produces a biphasic effect on accuracy in a visual target detection task in rats (2005) (14)
- A critique of recent studies on placebo effects of antidepressants: importance of research on active placebos (2000) (13)
- Individual differences in the energizing effects of caffeine on effort-based decision-making tests in rats (2018) (13)
- Extracellular GABA in globus pallidus increases during the induction of oral tremor by haloperidol but not by muscarinic receptor stimulation (2012) (13)
- Caffeine modulates voluntary alcohol intake in mice depending on the access conditions: Involvement of adenosine receptors and the role of individual differences (2019) (12)
- Lisdexamfetamine suppresses instrumental and consummatory behaviors supported by foods with varying degrees of palatability: Exploration of a binge-like eating model (2020) (11)
- The novel atypical dopamine transport inhibitor CT-005404 has pro-motivational effects in neurochemical and inflammatory models of effort-based dysfunctions related to psychopathology (2020) (11)
- The MAO-B inhibitor deprenyl reduces the oral tremor and the dopamine depletion induced by the VMAT-2 inhibitor tetrabenazine (2016) (11)
- Preference for vigorous exercise versus sedentary sucrose drinking: an animal model of anergia induced by dopamine receptor antagonism (2020) (11)
- Preference for Exercise vs. More Sedentary Reinforcers: Validation of an Animal Model of Tetrabenazine-Induced Anergia (2020) (11)
- c-Fos immunoreactivity in prefrontal, basal ganglia and limbic areas of the rat brain after central and peripheral administration of ethanol and its metabolite acetaldehyde (2013) (10)
- Oral Ingestion and Intraventricular Injection of Curcumin Attenuates the Effort-Related Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Motivational Symptoms of Depression. (2017) (9)
- Complexities and paradoxes in understanding the role of dopamine in incentive motivation and instrumental action: Exertion of effort vs. anhedonia (2022) (9)
- Assessment of a glycine uptake inhibitor in animal models of effort-related choice behavior: implications for motivational dysfunctions (2017) (9)
- Effort-related motivational effects of the pro-inflammatory cytokine interleukin 1-beta: studies with the concurrent fixed ratio 5/ chow feeding choice task (2013) (9)
- Fluorimetric Assay for the Determination of Glutamic Acid Decarboxylase Activity in Subregions of Rat Brain Tissue (1980) (8)
- Partial reversal of the effort-related motivational effects of tetrabenazine with the MAO-B inhibitor deprenyl (selegiline): Implications for treating motivational dysfunctions (2018) (8)
- Facing dyskinesia in Parkinson disease: Nondopaminergic approaches (2010) (8)
- The monoamine-oxidase B inhibitor deprenyl increases selection of high-effort activity in rats tested on a progressive ratio/chow feeding choice procedure: Implications for treating motivational dysfunctions (2018) (7)
- Detailed analysis of food-reinforced operant lever pressing distinguishes effects of a cannabinoid CB1 inverse agonist and dopamine D1 and D2 antagonists (2010) (7)
- Gas chromatographic-mass spectrometric determination of glutamic acid decarboxylase activity in subregions of rat brain. (1981) (7)
- O4 CENTRAL AND PERIPHERAL EFFECTS OF ETHANOL AND ACETALDEHYDE ON MEASURES OF ANXIETY IN RATS (2005) (6)
- Antidepressants and placebos: Conceptual problems and research strategies. (2002) (6)
- Induction of oral tremor in mice by the acetylcholinesterase inhibitor galantamine: Reversal with adenosine A2A antagonism (2016) (6)
- Insulin and ventral tegmental dopamine: what's impaired and what's intact? (2013) (6)
- The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation (2013) (6)
- Centrally-Acting Antagonist of Muscarinic M4 Receptors (1997) (5)
- Vigor, Effort-Related Aspects of Motivation and Anhedonia. (2022) (5)
- A role for accumbens neurons in exertion of effort and evaluating effort‐related costs of instrumental actions (Commentary on Day et al.) (2011) (5)
- Selection of sucrose concentration depends on the effort required to obtain it: studies using tetrabenazine, D1, D2, and D3 receptor antagonists (2015) (5)
- Neurobiology and pharmacology of activational and effort-related aspects of motivation: rodent studies (2018) (5)
- Immunocytochemistry Studies of Basal Ganglia Adenosine A2A Receptors in Rat and Human Tissue (2010) (4)
- Sex differences in lever pressing and running wheel tasks of effort-based choice behavior in rats: Suppression of high effort activity by the serotonin transport inhibitor fluoxetine (2021) (4)
- Impact of Caffeine on Ethanol Induced Stimulation and Sensitization: Changes in ERK and DARPP-32 Phosphorylation in Nucleus Accumbens. (2021) (4)
- The dopamine depleting agent tetrabenazine alters effort-related decision making as assessed by mouse touchscreen procedures (2020) (4)
- Neurobiology of Effort and the Role of Mesolimbic Dopamine (2016) (4)
- The non-selective adenosine antagonist theophylline reverses the effects of dopamine antagonism on tremor, motor activity and effort-based decision-making (2020) (4)
- Impact of Fluoxetine on Behavioral Invigoration of Appetitive and Aversively Motivated Responses: Interaction With Dopamine Depletion (2021) (4)
- Comparison between high doses of caffeine and theophylline on motor and axiogenic effects in CD1 mice: studies of acute and chronic administration (2011) (3)
- A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions (2022) (3)
- Sex differences in effort-related decision-making: role of dopamine D2 receptor antagonism (2021) (3)
- Effects of caffeine on ethanol-elicited place preference, place aversion and ERK phosphorylation in CD-1 mice (2020) (3)
- INTERFERENCE WITH ACCUMBENS DOPAMINE TRANSMISSION MAKES RATS MORE SENSITIVE TO WORK REQUIREMENTS BUT DOES NOT IMPAIR PRIMARY FOOD REINFORCEMENT (1999) (3)
- Periodic food presentation increases extracellular dopamine and metabolites in nucleus accumbens dialysis perfusates (1990) (3)
- Chapter 38 – Physiological and Behavioral Assessment of Tremor in Rodents (2015) (3)
- Subthalamic and Cortical Local Field Potentials Associated with Pilocarpine-Induced Oral Tremor in the Rat (2016) (3)
- Energizing effects of bupropion on effortful behaviors in mice under positive and negative test conditions: modulation of DARPP-32 phosphorylation patterns (2021) (3)
- The renaissance of acetaldehyde as a psychoactive compound: decades in the making (2014) (2)
- Effort-related decision making in humanized COMT mice: Effects of Val158Met polymorphisms and possible implications for negative symptoms in humans (2020) (2)
- Original Research Report In Vitro Generation of Dopaminergic Neurons from Adult Subventricular Zone Neural Progenitor Cells (2008) (2)
- Parsing the Role of Mesolimbic Dopamine in Specific Aspects of Motivation: Behavioral Activation, Invigoration, and Effort-Based Decision Making (2018) (2)
- Drugs, Brain and Behavior. 6th ed. (2011) (2)
- Editorial: Ethanol, Its Active Metabolites, and Their Mechanisms of Action: Neurophysiological and Behavioral Effects (2018) (2)
- Dopamine/Adenosine Interactions Related to Tremor in Animal Models of Parkinsonism (2015) (1)
- Effects of the dopamine depleting agent tetrabenazine on detailed temporal parameters of effort-related choice responding. (2022) (1)
- Critical review of RDoC approaches to the study of motivation with animal models: effort valuation/willingness to work. (2022) (1)
- The VMAT-2 inhibitor tetrabenazine alters effort-related decision making as measured by the T-maze barrier choice task: reversal with the adenosine A2A antagonist MSX-3 and the catecholamine uptake blocker bupropion (2014) (1)
- Effort-related motivational effects of the pro-inflammatory cytokine interleukin-6: pharmacological and neurochemical characterization (2016) (1)
- Synthesis and Characterization of All Four Isomers of the Muscarinic Agonist 2′-Methylspiro(1-azabicyclo(2.2.2)octane-3,4′-(1,3)dioxolane) (I). (1987) (1)
- S.2.4 - RUNNERS VS. COUCH POTATOES: DOPAMINE DEPLETION REDUCES SELECTION OF PHYSICAL EFFORT IN ANIMALS WITH LOW BUT NOT HIGH EXPERIENCE OF EXERCISE (2013) (1)
- COMPARATIVE RESEARCH ON CHILDHOOD HYPERKINESIS/-ATTENTION DEFICIT DISORDER (1996) (1)
- Demotivating outcome of asymmetrical Nucleus Accumbens disconnection for cocaine related disorder: a translational point of view. (2018) (1)
- Ethanol and Caffeine Effects on Social Interaction and Recognition in Mice : Involvement of Adenosine A 2 A and A 1 Receptors Journal Item (2019) (1)
- Neusilin® influences curcumin bioavailability and anti‐depressant efficacy in rats (1044.17) (2014) (0)
- Dopamine, effort, and behavioral activation: animal models of effort-related motivational symptoms in psychopathology (2016) (0)
- DA Neurons Promote the Instigation and Maintenance of Effortful Responding: A Commentary on Fischbach-Weiss, Reese, and Janak (2018) (0)
- Assessment of a glycine uptake inhibitor in animal models of effort-related choice behavior: implications for motivational dysfunctions (2017) (0)
- F.7 - IMPACT OF CAFFEINE ON VOLUNTARY ETHANOL INTAKE AND THE ALCOHOL DEPRIVATION EFFECT IN MICE (2013) (0)
- outputs c-Fos immunoreactivity in prefrontal , basal ganglia and limbic areas of the rat brain after central and peripheral administration of ethanol and its metabolite acetaldehyde Journal Item (2019) (0)
- Conference Proceeding: Dissociable effects of dopamine antagonists and cannabinoid CB1 antagonists: studies using the concurrent progressive ratio/chow feeding task (2012) (0)
- Pharmacological studies of effort-related decision making using mouse touchscreen procedures: effects of dopamine antagonism do not resemble reinforcer devaluation by removal of food restriction (2019) (0)
- SY02-4IMPACT OF DOPAMINE DEPLETION OR ENHANCEMENT ON ETHANOL CONSUMPTION IN RATS: FREE VERSUS WORK-MEDIATED ACCESS (2015) (0)
- Investigating the Neurobiology of Motivational Deficiencies in Major Depressive Disorder : 5-HT 1 B Receptor Involvement in Behavioral Effects of Fluoxetine ( Prozac ) (2019) (0)
- Lipopolysaccharide-induced changes in effort-related motivational function: Interactions with 2-deoxyglucose (2022) (0)
- Cannabinoid Cb 1 Receptor Antagonists/Inverse Agonists and Food-Seeking Behavior (2011) (0)
- Name City State/Province Name City State/Province (2014) (0)
- Using complex behavior to understand brain mechanisms in health and disease (2022) (0)
- Dopamine/adenosine interaction in effort-related processes in rodents: Studies using T-Maze paradigm in mice (2008) (0)
- Choosing voluntary exercise over sucrose consumption depends upon dopamine transmission: effects of haloperidol in wild type and adenosine A2AKO mice (2015) (0)
- Patterns of Neural Responses, Pavlovian-to-Instrumental Transfer, and Prediction of Relapse (2019) (0)
- Differentiating effort-related aspects of motivation from reinforcement learning: commentary on Soder et al. “Dose–response effects of d-amphetamine on effort-based decision-making and reinforcement learning” (2021) (0)
- The Novel Cannabinoid CB1 Receptor Neutral Antagonist Am4113 Suppresses Food Intake and Food-Reinforced Behavior but Does not Induce Signs of Nausea in Rats (2008) (0)
- WITHDRAWN: Effects of cannabinoid antagonists on intake of different foods (2006) (0)
- Book Reviews : Neurotransmitter Interactions and Cognitive Function (1995) (0)
- The Impact of Ethanol Plus Caffeine Exposure on Cognitive, Emotional, and Motivational Effects Related to Social Functioning (2019) (0)
- Review for "The Role of the Nucleus Accumbens in Learned Approach Behavior Diminishes with Training" (2019) (0)
- Deoxyglucose uptake in rat cerebral cortex following ibotenic acid lesions of the nucleus basalis magnocellularis (1985) (0)
- Parkinson's disease after psychosurgery for the treatment of cocaine addiction. (2021) (0)
- PCP-induced abnormal social behavior: Possible relation to schizophrenic pharmacology (1991) (0)
- 250. Anergia and Effort-Related Aspects of Motivational Dysfunction in Animal Models of Depressive Symptoms: The Role of Mesolimbic Dopamine and Related Circuitry (2018) (0)
- Effects of Lisdexamfetamine and Haloperidol on a Binge-Like Eating Model & Preliminary Investigations of the Dopaminergic Mechanism Underlying Binge Eating Disorder (BED) (2020) (0)
- B15 AN ANIMAL MODEL FOR ASSESSING THE POTENTIAL ANTIPARKINSONIAN CHARACTERISTICS OF M4 MUSCARINIC ANTAGONISTS: EFFECTS OF THE PARTIALLY SELECTIVE M4 ANTAGONIST TROPICAMIDE (2005) (0)
- S.2.1 - DEVELOPMENT OF ANIMAL MODELS OF THE EFFORT-RELATED SYMPTOMS OF DEPRESSION: EFFECTS OF TETRABENAZINE AND REVERSAL WITH ANTIDEPRESSANTS (2013) (0)
- Assessment of the effects of increased operant response force requirements possible implications for the investigation of the effects of nucleus accumbens dopamine depletions (2000) (0)
- Neuroactive metabolites of ethanol: a behavioral and neurochemical synopsis (2015) (0)
- Striatal dopamine depletion produced by the VMAT-2 inhibitor tetrabenazine induces tremulous jaw movements: Implications for rodent models of parkinsonian tremor (2012) (0)
- Effort-Related Motivational Effects of Novel Atypical Dopamine Transport Inhibitors: Implications for Psychopathology (2022) (0)
- E.21 - CAFFEINE INDUCES ANXIETY AND IMPAIRS SOCIAL INTERACTION IN MICE: THE ROLE OF ADENOSINE RECEPTORS AND IMPACT ON ETHANOL (2013) (0)
- Review for "Evaluation of cognitive effort in rats is not critically dependent on ventrolateral orbitofrontal cortex" (2020) (0)
- Effects of lisdexamfetamine and s-citalopram, alone and in combination, on effort-related choice behavior in the rat (2015) (0)
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