John N. Danesh
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John N. Daneshbiology Degrees
Biology
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Bioinformatics
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Genetics
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Biology
John N. Danesh's Degrees
- Masters Bioinformatics Imperial College London
Why Is John N. Danesh Influential?
(Suggest an Edit or Addition)John N. Danesh's Published Works
Published Works
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age (2015) (5094)
- Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
- C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. (2004) (2975)
- Discovery and Refinement of Loci Associated with Lipid Levels (2013) (2475)
- Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. (1998) (2171)
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study (2012) (2002)
- Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. (2010) (1978)
- Serious mental disorder in 23 000 prisoners: a systematic review of 62 surveys (2002) (1970)
- C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis (2010) (1950)
- Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk (2011) (1928)
- Diabetes mellitus, fasting glucose, and risk of cause-specific death. (2011) (1874)
- Prevalence of serious mental disorder in 7000 refugees resettled in western countries: a systematic review (2005) (1855)
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes (2012) (1839)
- Defining the role of common variation in the genomic and biological architecture of adult human height (2014) (1805)
- Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses (2000) (1725)
- Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents (2016) (1582)
- A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease (2015) (1567)
- Major lipids, apolipoproteins, and risk of vascular disease. (2009) (1563)
- Large-scale association analysis identifies new risk loci for coronary artery disease (2012) (1507)
- Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease (2017) (1358)
- Triglycerides and the Risk of Coronary Heart Disease: 10 158 Incident Cases Among 262 525 Participants in 29 Western Prospective Studies (2007) (1331)
- Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. (2009) (1329)
- Interpretation of the evidence for the efficacy and safety of statin therapy (2016) (1290)
- Chronic infections and coronary heart disease: is there a link? (1997) (1289)
- New genetic loci link adipose and insulin biology to body fat distribution (2014) (1227)
- Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. (2005) (1195)
- Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis. (2014) (1046)
- Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial (2000) (962)
- C-reactive protein, fibrinogen, and cardiovascular disease prediction. (2012) (952)
- Lipoprotein(a) and Coronary Heart Disease: Meta-Analysis of Prospective Studies (2000) (934)
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility (2014) (933)
- The genetic architecture of type 2 diabetes (2016) (927)
- The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease (2016) (885)
- Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity (2020) (819)
- Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England (2021) (806)
- Genomic atlas of the human plasma proteome (2018) (799)
- Common variants associated with plasma triglycerides and risk for coronary artery disease (2013) (767)
- Association of apolipoprotein E genotypes with lipid levels and coronary risk. (2007) (731)
- Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies (2018) (727)
- Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies (2018) (727)
- Genetic associations with valvular calcification and aortic stenosis. (2013) (723)
- PhenoScanner: a database of human genotype–phenotype associations (2016) (678)
- Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (659)
- Long-Term Interleukin-6 Levels and Subsequent Risk of Coronary Heart Disease: Two New Prospective Studies and a Systematic Review (2008) (655)
- SARS-CoV-2 evolution during treatment of chronic infection (2021) (647)
- Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies (2012) (646)
- A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease (2011) (638)
- Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies (2010) (631)
- Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. (2016) (630)
- Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. (2011) (589)
- Lipoprotein-associated phospholipase A2 and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies (2010) (588)
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2018) (578)
- Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data (2011) (556)
- Association of Cardiometabolic Multimorbidity With Mortality. (2015) (535)
- Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci (2011) (518)
- PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations (2019) (511)
- Rare and low-frequency coding variants alter human adult height (2016) (511)
- Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk. (2008) (493)
- Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study (2021) (488)
- Association analyses based on false discovery rate implicate new loci for coronary artery disease (2017) (476)
- Lipid-related markers and cardiovascular disease prediction. (2012) (457)
- Mapping the human genetic architecture of COVID-19 (2021) (455)
- Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis. (2014) (454)
- Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease (2016) (434)
- Exome-wide association study of plasma lipids in >300,000 individuals (2017) (428)
- Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction (2014) (426)
- World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions (2019) (423)
- Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66 155 cases and 91 307 controls (2006) (417)
- Adiponectin and Coronary Heart Disease: A Prospective Study and Meta-Analysis (2006) (412)
- Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis (2001) (403)
- Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
- Genetics of Blood Lipids Among ~300,000 Multi-Ethnic Participants of the Million Veteran Program (2018) (387)
- C‐reactive protein and coronary heart disease: a critical review (2008) (381)
- Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders (2016) (363)
- UK Biobank: Current status and what it means for epidemiology (2012) (362)
- B-Type Natriuretic Peptides and Cardiovascular Risk: Systematic Review and Meta-Analysis of 40 Prospective Studies (2009) (361)
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
- Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults (2018) (359)
- Seventy-five genetic loci influencing the human red blood cell (2012) (357)
- Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease (2019) (356)
- Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study. (2015) (347)
- The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals (2016) (347)
- Fibrin D-Dimer and Coronary Heart Disease: Prospective Study and Meta-Analysis (2001) (345)
- Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis (2018) (340)
- Haematocrit, viscosity, erythrocyte sedimentation rate: meta-analyses of prospective studies of coronary heart disease. (2000) (336)
- Chlamydia pneumoniae IgG titres and coronary heart disease: prospective study and meta-analysis. (2000) (309)
- Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. (2016) (309)
- Four paraoxonase gene polymorphisms in 11 212 cases of coronary heart disease and 12 786 controls: meta-analysis of 43 studies (2004) (300)
- Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes (2017) (294)
- Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing (2016) (294)
- Inactivating mutations in NPC1L1 and protection from coronary heart disease. (2014) (289)
- Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation (2015) (285)
- Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7 (2021) (285)
- Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. (2012) (282)
- Risk factors for coronary heart disease and infection with Helicobacter pylori: meta-analysis of 18 studies (1998) (281)
- ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. (2017) (278)
- von Willebrand factor and coronary heart disease: prospective study and meta-analysis. (2002) (275)
- Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study. (2011) (265)
- Risk factors for coronary heart disease and acute-phase proteins. A population-based study. (1999) (263)
- Lipoprotein(a) levels and risk of future coronary heart disease: large-scale prospective data. (2008) (259)
- Chronic kidney disease and risk of major cardiovascular disease and non-vascular mortality: prospective population based cohort study (2010) (258)
- New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. (2018) (257)
- Plasma Homocysteine and Coronary Heart Disease: Systematic Review of Published Epidemiological Studies (1998) (254)
- A road map for efficient and reliable human genome epidemiology (2006) (252)
- A catalog of genetic loci associated with kidney function from analyses of a million individuals (2019) (252)
- Associations between apolipoprotein B, apolipoprotein AI, the apolipoprotein B/AI ratio and coronary heart disease: a literature‐based meta‐analysis of prospective studies (2006) (249)
- Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels (2018) (246)
- Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity (2017) (244)
- Serum Uric Acid and Coronary Heart Disease in 9,458 Incident Cases and 155,084 Controls: Prospective Study and Meta-Analysis (2005) (244)
- Coronary heart disease and iron status: meta-analyses of prospective studies. (1999) (244)
- The Polygenic and Monogenic Basis of Blood Traits and Diseases (2020) (242)
- Apolipoprotein(a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58,000 participants. (2010) (241)
- Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension (2016) (234)
- Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
- Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations (2020) (225)
- Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms (2017) (224)
- Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption (2014) (224)
- Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: individual participant meta-analysis of 154,211 adults in 31 prospective studies: the fibrinogen studies collaboration. (2007) (224)
- Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases (2013) (220)
- Genetically determined height and coronary artery disease. (2015) (220)
- Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis. (2012) (220)
- Association of Genetic Variants Related to CETP Inhibitors and Statins With Lipoprotein Levels and Cardiovascular Risk (2017) (216)
- Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease (2017) (204)
- Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-European case-cohort analysis (2018) (202)
- SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe. (2021) (200)
- Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes (2011) (197)
- Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure underpinning obesity (2017) (193)
- Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors (2017) (190)
- Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors (2017) (190)
- Glycated hemoglobin measurement and prediction of cardiovascular disease. (2014) (189)
- Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study (2011) (185)
- Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases (2019) (183)
- Leptin and coronary heart disease: prospective study and systematic review. (2009) (180)
- Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias (2012) (180)
- Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease (2016) (179)
- Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease (2017) (179)
- Associations between differential leucocyte count and incident coronary heart disease: 1764 incident cases from seven prospective studies of 30,374 individuals. (2004) (176)
- Improving reporting standards for polygenic scores in risk prediction studies (2020) (175)
- Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease (2018) (175)
- Markers of Dysglycaemia and Risk of Coronary Heart Disease in People without Diabetes: Reykjavik Prospective Study and Systematic Review (2010) (175)
- The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation (2020) (171)
- Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India (2013) (168)
- Mendelian Randomization Study of ACLY and Cardiovascular Disease (2019) (166)
- Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels. (2016) (164)
- Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals (2020) (161)
- Five Glutathione S-Transferase Gene Variants in 23,452 Cases of Lung Cancer and 30,397 Controls: Meta-Analysis of 130 Studies (2006) (159)
- Suicides in male prisoners in England and Wales, 1978–2003 (2005) (158)
- Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis (2017) (156)
- Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'. (2006) (156)
- Big data from electronic health records for early and late translational cardiovascular research: challenges and potential (2017) (155)
- Coronary heart disease, Helicobacter pylori, dental disease, Chlamydia pneumoniae, and cytomegalovirus: meta-analyses of prospective studies. (1999) (155)
- The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases (2007) (155)
- Multiple rare alleles at LDLR and APOA5 confer risk for early-onset myocardial infarction (2014) (147)
- Helicobacter pylori infection and early onset myocardial infarction: case-control and sibling pairs study (1999) (147)
- Cardiovascular Risk Factors Associated With Venous Thromboembolism (2019) (143)
- Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis (2017) (137)
- Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes (2016) (136)
- Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease (2017) (135)
- Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study. (2016) (134)
- Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease (2013) (133)
- Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. (2011) (133)
- Prospective study of potentially virulent strains of Helicobacter pylori and coronary heart disease in middle-aged men. (2000) (132)
- Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ethnic meta-analysis (2020) (127)
- Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease (1999) (127)
- Exome Aggregation Consortium (2016) (125)
- Tissue plasminogen activator antigen and coronary heart disease. Prospective study and meta-analysis. (2004) (122)
- A network of investigator networks in human genome epidemiology. (2005) (121)
- Association between Walking Speed and Age in Healthy, Free-Living Individuals Using Mobile Accelerometry—A Cross-Sectional Study (2011) (120)
- Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis. (2008) (118)
- Chlamydia pneumoniae IgA titres and coronary heart disease: prospective study and meta-analysis. (2002) (116)
- Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease. (2019) (115)
- The Emergence of Networks in Human Genome Epidemiology: Challenges and Opportunities (2007) (112)
- The Pakistan Risk of Myocardial Infarction Study: a resource for the study of genetic, lifestyle and other determinants of myocardial infarction in South Asia (2009) (111)
- Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies (2010) (106)
- Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis (2015) (106)
- The INTERVAL trial to determine whether intervals between blood donations can be safely and acceptably decreased to optimise blood supply: study protocol for a randomised controlled trial (2014) (106)
- Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study (2020) (103)
- EPIC-Heart: The cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries (2007) (101)
- Renal Function and Risk of Coronary Heart Disease in General Populations: New Prospective Study and Systematic Review (2007) (99)
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (98)
- Regression dilution methods for meta-analysis: assessing long-term variability in plasma fibrinogen among 27,247 adults in 15 prospective studies. (2006) (93)
- Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. (2012) (93)
- A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (2016) (92)
- A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease (2019) (90)
- Systematic review of the epidemiological evidence on Helicobacter pylori infection and nonulcer or uninvestigated dyspepsia. (2000) (90)
- A Prospective Study of Helicobacter pylori Seropositivity and the Risk for Future Myocardial Infarction among Socioeconomically Similar U.S. Men (2001) (89)
- Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke (2019) (88)
- The association between psychiatric diagnosis and violent re-offending in adult offenders in the community (2008) (88)
- Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria (2019) (86)
- Postcodes as useful markers of social class: population based study in 26 000 British households. (1999) (85)
- Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis (2016) (83)
- Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant (2021) (82)
- Association Between Depressive Symptoms and Incident Cardiovascular Diseases. (2020) (82)
- Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses (2021) (79)
- Polygenic basis and biomedical consequences of telomere length variation (2021) (79)
- Epidemiology of spinal cord injury in New Zealand. (1993) (79)
- Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease (2017) (78)
- Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies (2018) (78)
- Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length (2020) (74)
- Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19 (2020) (73)
- Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci (2019) (72)
- Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling (2018) (70)
- A cross-platform approach identifies genetic regulators of human metabolism and health (2021) (69)
- GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm (2013) (68)
- Monitoring indirect impact of COVID-19 pandemic on services for cardiovascular diseases in the UK (2020) (68)
- PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION (2018) (67)
- Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk. (2004) (67)
- Hemostatic and rheological variables and risk of cardiovascular disease. (2002) (65)
- Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study (2016) (65)
- Association of the 9p21.3 Locus With Risk of First-Ever Myocardial Infarction in Pakistanis: Case-Control Study in South Asia and Updated Meta-Analysis of Europeans (2010) (65)
- Consumption of Meat, Fish, Dairy Products, and Eggs and Risk of Ischemic Heart Disease (2019) (65)
- Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease (2017) (64)
- Circulating concentrations of insulin markers and coronary heart disease: a quantitative review of 19 Western prospective studies. (2007) (63)
- Plasma fibrinogen and fibrinogen genotypes in 4685 cases of myocardial infarction and in 6002 controls: Test of causality by "Mendelian randomisation" (2000) (63)
- Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource (2021) (62)
- Assessing the causal association of glycine with risk of cardio-metabolic diseases (2019) (60)
- Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses (2021) (60)
- NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease (2017) (59)
- C-reactive protein and coronary disease: is there a causal link? (2009) (59)
- Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease (2018) (59)
- Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries (2020) (57)
- Collaborative meta-analysis of prospective studies of plasma fibrinogen and cardiovascular disease (2004) (57)
- Paraoxonase polymorphisms and coronary heart disease (2004) (56)
- Collaborative meta-analysis of individual participant data from observational studies of Lp-PLA2 and cardiovascular diseases. (2007) (55)
- Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study (2018) (55)
- Systematically missing confounders in individual participant data meta-analysis of observational cohort studies (2009) (54)
- Automated typing of red blood cell and platelet antigens: a whole-genome sequencing study. (2018) (54)
- Parity, breastfeeding and risk of coronary heart disease: A pan-European case–cohort study (2016) (53)
- Persistent infection and vascular disease: a systematic review. (1998) (53)
- Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (53)
- Assessing Risk Prediction Models Using Individual Participant Data From Multiple Studies (2013) (52)
- Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort). (2013) (51)
- New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 Individuals (2017) (50)
- Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference (2018) (49)
- How often does surgery for peptic ulceration eradicate Helicobacter pylori? Systematic review of 36 studies (1998) (49)
- Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E ε2/ε3/ε4 genotype (2003) (48)
- Eradication of Helicobacter pylori and non-ulcer dyspepsia (2000) (47)
- Lipoprotein‐associated phospholipase A2 activity and mass in relation to vascular disease and nonvascular mortality (2010) (47)
- Haemostatic and inflammatory markers are independently associated with myocardial infarction in men and women. (2012) (47)
- Antibiotics in the prevention of heart attacks (2005) (46)
- An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors (2019) (46)
- Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease (2019) (46)
- Platelet function is modified by common sequence variation in megakaryocyte super enhancers (2017) (46)
- Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants (2021) (45)
- Collaborative pooled analysis of data on C-reactive protein gene variants and coronary disease: judging causality by Mendelian randomisation (2008) (45)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (45)
- Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use (2019) (45)
- Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians. (2020) (45)
- Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2 (2016) (44)
- Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations (2020) (44)
- Dietary fibre intake and ischaemic heart disease mortality: the European Prospective Investigation into Cancer and Nutrition-Heart study (2012) (44)
- Measures to assess the prognostic ability of the stratified Cox proportional hazards model (2009) (44)
- Angiotensin converting enzyme insertion or deletion polymorphism and coronary restenosis: meta-analysis of 16 studies (2002) (43)
- Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (43)
- Smoldering arteries? Low-grade inflammation and coronary heart disease. (1999) (42)
- Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases. (2019) (42)
- Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment (2018) (40)
- A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis (2021) (40)
- Chlamydia pneumoniae IgA titres and coronary heart disease; prospective study and meta-analysis. (2002) (40)
- The HuGENetTM HuGE Review Handbook, version 1.0 (2006) (39)
- Diagnostic Yield of Sequencing Familial Hypercholesterolemia Genes in Patients with Severe Hypercholesterolemia. (2016) (39)
- Association of menopausal characteristics and risk of coronary heart disease: a pan-European case–cohort analysis (2019) (39)
- Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk (2014) (37)
- Accuracy of UK Rapid Test Consortium (UK-RTC) “AbC-19 Rapid Test” for detection of previous SARS-CoV-2 infection in key workers: test accuracy study (2020) (37)
- Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies (2021) (37)
- Use of Repeated Blood Pressure and Cholesterol Measurements to Improve Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis (2017) (37)
- Are Myocardial Infarction–Associated Single-Nucleotide Polymorphisms Associated With Ischemic Stroke? (2012) (35)
- Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. (2016) (34)
- Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma (2017) (33)
- C-reactive protein in healthy and in sick populations. (2000) (33)
- Genetic effects on promoter usage are highly context-specific and contribute to complex traits (2018) (32)
- Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease (2020) (31)
- The Bangladesh Risk of Acute Vascular Events (BRAVE) Study: objectives and design (2015) (31)
- The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis (2020) (30)
- Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases (2019) (29)
- Genetic Determinants of Major Blood Lipids in Pakistanis Compared With Europeans (2010) (29)
- Is Helicobacter pylori a Factor in Coronary Atherosclerosis? (1999) (29)
- Genome-Wide Association Analysis of Young Onset Stroke Identifies a Locus on Chromosome 10 q 25 Near HABP 2 (2015) (28)
- A first update on mapping the human genetic architecture of COVID-19 (2022) (27)
- Effect of communicating phenotypic and genetic risk of coronary heart disease alongside web-based lifestyle advice: the INFORM Randomised Controlled Trial (2019) (27)
- Stroke genetics informs drug discovery and risk prediction across ancestries (2022) (26)
- Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits (2018) (26)
- Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention (2018) (26)
- Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition (2018) (26)
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2018) (26)
- Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (2017) (25)
- Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E epsilon2/epsilon3/epsilon4 genotype. (2003) (24)
- Genetically modulated educational attainment and coronary disease risk. (2019) (24)
- Shorter leukocyte telomere length is associated with adverse COVID-19 outcomes: A cohort study in UK Biobank (2021) (23)
- Turning the pump handle: evolving methods for integrating the evidence on gene-disease association. (2007) (23)
- Lipoprotein(a) levels and risk of future coronary heart disease (2008) (23)
- Measurement and initial characterization of leukocyte telomere length in 474,074 participants in UK Biobank (2022) (23)
- Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles (2016) (22)
- Association of Plasma Vitamin D Metabolites With Incident Type 2 Diabetes: EPIC-InterAct Case-Cohort Study (2018) (21)
- Prevalence of epilepsy in prisoners: systematic review (2002) (21)
- Development and validation of a universal blood donor genotyping platform: a multinational prospective study. (2020) (21)
- Large genome-wide association study identifies three novel risk variants for restless legs syndrome (2020) (21)
- DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes (2018) (21)
- Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2017) (20)
- Consequences of natural perturbations in the human plasma proteome (2017) (20)
- Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases (2021) (20)
- A major population resource of 474,074 participants in UK Biobank to investigate determinants and biomedical consequences of leukocyte telomere length. (2021) (20)
- Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment (2018) (20)
- Recruitment and representativeness of blood donors in the INTERVAL randomised trial assessing varying inter-donation intervals (2016) (19)
- Is Helicobacter pylori infection a cause of gastric neoplasia (1999) (18)
- High prevalence of potentially virulent strains ofHelicobacter pylori in the general male British population (2000) (18)
- Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential (2022) (17)
- COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records (2022) (17)
- Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (17)
- ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study (2020) (16)
- Is there a link between chronic Helicobacter pylori infection and coronary heart disease? (2003) (16)
- Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis (2020) (16)
- Glycemic index, glycemic load, and risk of coronary heart disease: a pan-European cohort study. (2020) (16)
- Helicobacter pylori and gastric cancer: time for mega-trials? (1999) (15)
- Genomic evaluation of circulating proteins for drug target characterisation and precision medicine (2020) (15)
- Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci (2020) (15)
- Genetic analysis of over one million people identifies 535 novel loci for blood pressure (2017) (14)
- Accuracy of four lateral flow immunoassays for anti SARS-CoV-2 antibodies: a head-to-head comparative study (2021) (14)
- NT-proBNP is associated with coronary heart disease risk in healthy older women but fails to enhance prediction beyond established risk factors: results from the British Women's Heart and Health Study. (2010) (14)
- Helicobacter pylori screening and gastric cancer (1996) (14)
- Author Correction: Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease (2018) (14)
- Longer-term efficiency and safety of increasing the frequency of whole blood donation (INTERVAL): extension study of a randomised trial of 20 757 blood donors (2019) (13)
- Human knockouts in a cohort with a high rate of consanguinity (2015) (13)
- Longer-term efficiency and safety of increasing the frequency of whole blood donation (INTERVAL): extension study of a randomised trial of 20 757 blood donors (2019) (13)
- BRCA2 Variants and cardiovascular disease in a multi-ethnic study (2012) (13)
- Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. (2011) (13)
- Dietary Fatty Acids, Macronutrient Substitutions, Food Sources and Incidence of Coronary Heart Disease: Findings From the EPIC‐CVD Case‐Cohort Study Across Nine European Countries (2021) (12)
- Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2019) (12)
- New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries (2018) (12)
- Risk Factors for Coronary Heart Disease and Persistent Infection with Chlamydia Pneumoniae or Cytomegalovirus: A Population-Based Study (1999) (12)
- Classical and Emerging Risk Factors for Cardiovascular Disease. [Miscellaneous] (2002) (12)
- Heterozygous ABCG5 Gene Deficiency and Risk of Coronary Artery Disease (2020) (11)
- Effects of adiposity on the human plasma proteome: observational and Mendelian randomisation estimates (2020) (11)
- Prospective Study and Systematic Review (2009) (11)
- Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease. (2020) (11)
- Information and Risk Modification Trial (INFORM): design of a randomised controlled trial of communicating different types of information about coronary heart disease risk, alongside lifestyle advice, to achieve change in health-related behaviour (2015) (11)
- Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes (2020) (11)
- Discovery of 318 novel loci for type-2 diabetes and related micro- and macrovascular outcomes among 1.4 million participants in a multi-ethnic meta-analysis (2019) (11)
- ANGPTL 3 De fi ciency and Protection Against Coronary Artery Disease (2017) (10)
- Quality control and removal of technical variation of NMR metabolic biomarker data in ~120,000 UK Biobank participants (2021) (10)
- Modifiable traits, healthy behaviours, and leukocyte telomere length: a population-based study in UK Biobank (2022) (10)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (10)
- Epidemiology: A human germ project? (1997) (10)
- Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation (2019) (9)
- Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes (2021) (9)
- Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study (2021) (9)
- Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19 (2021) (9)
- NOX 1 loss-of-function genetic variants in patients with inflammatory bowel disease (2017) (9)
- Epidemiology of spinal cord injury. (1991) (9)
- Association of Cardiometabolic Multimorbidity With Mortality The Emerging Risk Factors Collaboration (2015) (9)
- Plant foods, dietary fibre and risk of ischaemic heart disease in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort (2020) (9)
- C-reactive protein, fibrinogen, and cardiovascular risk. (2013) (8)
- Comparison of four methods to measure haemoglobin concentrations in whole blood donors (COMPARE): A diagnostic accuracy study (2020) (8)
- Erratum to: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits : (Nature Genetics, (2018), 50, 10, (1412-1425), 10.1038/s41588-018-0205-x) (2018) (8)
- Rare and common genetic determinants of metabolic individuality and their effects on human health (2022) (8)
- Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes (2020) (8)
- Risk factors: Lipoprotein(a) and coronary disease—moving closer to causality (2009) (8)
- Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke (2018) (7)
- Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites (2022) (7)
- Genetic Analyses of Blood Cell Structure for Biological and Pharmacological Inference (2020) (7)
- The 4C Initiative (Clinical Care for Cardiovascular disease in the COVID-19 pandemic): monitoring the indirect impact of the coronavirus pandemic on services for cardiovascular diseases in the UK (2020) (6)
- Risk factors and prediction models for incident heart failure with reduced and preserved ejection fraction (2021) (6)
- Learning polygenic scores for human blood cell traits (2020) (6)
- Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)) (2012) (6)
- Postcodes as useful markers of income in 26,000 British households. (1999) (6)
- Commentary on "A meta-analysis but not a systematic review: an evaluation of the Global BMI Mortality Collaboration". (2017) (5)
- Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission (2022) (5)
- HeterozygousABCG5Gene Deficiency and Risk of Coronary Artery Disease (2020) (5)
- The influence of rare variants in circulating metabolic biomarkers (2018) (5)
- Strong correlation between Helicobacter pylori seropositivity and Chlamydia pneumoniae IgG concentrations. (1998) (5)
- Helicobacter pylori infection and coronary heart disease: a critical look (1998) (4)
- Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (2018) (4)
- Fish hook injuries--wounded anglers and string theory. (1992) (4)
- Mental disorders in prisoners (2002) (4)
- LPA variants, risk of coronary disease, and estimated clinical benefit of lipoprotein(a) lowering therapies: A mendelian randomization analysis (2018) (4)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (4)
- Association of shorter leucocyte telomere length with risk of frailty (2022) (4)
- Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease (2018) (4)
- Elucidating mechanisms of genetic cross-disease associations: an integrative approach implicates protein C as a causal pathway in arterial and venous diseases (2020) (4)
- South Asian Patient Population Genetics Reveal Strong Founder Effects and High Rates of Homozygosity – New Resources for Precision Medicine (2020) (4)
- Physical activity attenuates but does not eliminate coronary heart disease risk amongst adults with risk factors: EPIC-CVD case-cohort study. (2022) (3)
- Soluble adhesion molecules and coronary heart disease. Authors' reply (2002) (3)
- An atlas of genetic scores to predict multi-omic traits (2022) (3)
- Validation of self-administered nasal swabs and postage for the isolation of Staphylococcus aureus (2016) (3)
- Machine learning optimized polygenic scores for blood cell traits identify sex-specific trajectories and genetic correlations with disease (2022) (3)
- Causal analyses, statistical efficiency and phenotypic precision through Recall-by-Genotype study design (2017) (3)
- Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (3)
- Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease (2021) (3)
- Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases (2020) (3)
- Annual Meeting of the World Federation of Neurology Research Group on Neuroepidemiology. pp 121–127 (1993) (3)
- Cardiovascular Disease Risk Prediction Factors—Reply (2012) (3)
- Department of Error (2010) (3)
- Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: prospective cohort study and modelling analysis (2019) (3)
- Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke (2022) (3)
- Older biological age is associated with adverse COVID-19 outcomes: A cohort study in UK Biobank (2021) (3)
- H. pylori and diabetes. (1997) (3)
- Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (2)
- Genetically personalised organ-specific metabolic models in health and disease (2022) (2)
- Metabolic mediators of body-mass index and cardiovascular risk (2014) (2)
- Mapping genetic determinants of 184 circulating proteins in 26,494 individuals to connect proteins and disease. (2021) (2)
- A cross-platform approach identifies genetic regulators of human metabolism and health (2021) (2)
- A genome-wide association study in Indian Asians identifies five novel genetic variants for type-2 diabetes (2011) (2)
- Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses (2022) (2)
- Efficiency and safety of varying the frequency of whole blood donation: randomised trial of 45,000 donors (2017) (2)
- Estimating the contribution of Helicobacter pylori to gastric cancer (2000) (2)
- Body-mass index, abdominal adiposity, and cardiovascular risk – Authors' reply (2011) (2)
- Risk thresholds for alcohol consumption – Authors' reply (2018) (2)
- Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease (2019) (2)
- Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke (2020) (2)
- Body-mass index and all-cause mortality – Authors' reply (2017) (2)
- C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease (2004) (2)
- C-reactive protein and coronary heart disease - Reply (2004) (1)
- ANGPTL3 De fi ciency and Protection Against Coronary Artery Disease (1)
- 71 A genome-wide association study in Indian Asians identifies four susceptibility loci for type-2 diabetes (2011) (1)
- Helicobacter pylori and myocardial infection - Exclusion criteria were inappropriate - Reply (2000) (1)
- Milk intake and incident stroke and CHD in populations of European descent: a Mendelian randomisation study (2021) (1)
- Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer’s disease (2022) (1)
- Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition (2020) (1)
- The Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes - the EPIC-InterAct Study Short running title: Iron Metabolism and Type 2 Diabetes Incidence (2016) (1)
- Abstract 14351: Increased Levels of IgM Autoantibodies to Oxidation-Specific Epitopes are Inversely Associated With Coronary Heart Disease: Analyses of Data From 204,257 Participants (2015) (1)
- Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease (2022) (1)
- Genetically predicted levels of the human plasma proteome and risk of stroke: a Mendelian Randomization study (2021) (1)
- Coronary heart disease. (1971) (1)
- Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution (2019) (1)
- Triglyceride-mediated pathways and coronary heart disease – Authors' reply (2010) (1)
- Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)) (2012) (1)
- Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank (2022) (1)
- Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index (2021) (1)
- Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (1)
- An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript. (2021) (1)
- Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits (2018) (1)
- Genome-Wide Association Study of Over One Million Participants Identifies 49 Novel Loci Associated With Coronary Artery Disease (2019) (1)
- The need for risk factor assessment in atherothrombotic vascular disease. (2002) (1)
- Discovery and Refinement Supplementary (2015) (1)
- Mental disorders in prisoners. Authors' reply (2002) (1)
- Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations (2022) (1)
- Modifiable traits, healthy behaviours, and leucocyte telomere length (2021) (1)
- Developing Genome-wide Polygenic Risk Scores for Coronary Artery Disease in South Asians (2020) (1)
- Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus (2022) (1)
- Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke (2022) (1)
- Title Page / Abstracts / Session I / Poster Session / Session II (1993) (1)
- Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries (2022) (1)
- Haemostatic and inflammatory markers in coronary heart disease (2005) (0)
- Telomere Length and Risk of Incident Fracture and Arthroplasty: Findings From UK Biobank (2022) (0)
- Ischemic Stroke? Associated Single-Nucleotide Polymorphisms Associated With - Are Myocardial Infarction (2012) (0)
- The Malaysian Acute Vascular Events Risk (MAVERIK) study: a resource to study genetic and other determinants of first-ever myocardial infarction in Malaysia (Preprint) (2021) (0)
- Genomic discovery and functional validation of MRP1 as a novel fetal hemoglobin modulator and potential therapeutic target in sickle cell disease. (2023) (0)
- Systematic Reviews andMeta-and Pooled Analyses (2017) (0)
- Abstract 567: Causal Assessment of Uric Acid and Risk of Myocardial Infarction, a Mendelian Randomization Study (2013) (0)
- Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2021) (0)
- Antibiotics in the prevention of coronary heart disease: review of the randomised trials (2001) (0)
- The bacteria craze (multiple letters) [12] (1999) (0)
- Annual Meeting of the World Federation of Neurology Research Group on Neuroepidemiology. pp 128–138 (1993) (0)
- Mapping pQTLs of circulating inflammatory proteins identifies drivers of and novel therapeutic targets (2023) (0)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
- Genetic Determinants of Major Blood Lipids in Pakistan Is Compared with Europeans Running title: Saleheen et al.; Genetic loci for major lipids in Pakistan (2010) (0)
- Leptin and Coronary Heart Disease (2008) (0)
- Helicobacter pylori and surgery - Reply (1998) (0)
- Editorial Board (2014) (0)
- Investigating the Association of Rare Genetic Variants with Blood Pressure traits (2015) (0)
- Investigating Genetic and Other Determinants of First-Onset Myocardial Infarction in Malaysia: Protocol for the Malaysian Acute Vascular Events Risk Study (2022) (0)
- Adiponectin and Coronary Heart Disease (2006) (0)
- Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference (2018) (0)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (0)
- Food choices characterized by the Nutri-Score nutrient profile and risk of cardiovascular diseases (2022) (0)
- Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing (2019) (0)
- Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (0)
- Review of The Covenant of Bahá’u’lláh and The Ministry of the Custodians 1957-1963: An Account of the Stewardship of the Hands of the Cause (1993) (0)
- Abstract 154: Sex-specific Genome Wide Association Study Of Early-onset Ischemic Stroke (2022) (0)
- Chronic disease research in Europe and the need for integrated population cohorts (2018) (0)
- Physicians' Warnings for Unfit Drivers and Risk of Road Crashes (2013) (0)
- Response to Letter Regarding Article, “Adiponectin and Coronary Heart Disease: A Prospective Study and Meta-Analysis” (2007) (0)
- Associations of cardiovascular risk factors with venous thromboembolism (2019) (0)
- Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus (2022) (0)
- 38 VITAMIN D AND CARDIOVASCULAR DISEASE (2012) (0)
- Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus (2022) (0)
- Abstract 16492: A Study of 63,253 Cases and 126,820 Controls Identifies Multiple Novel Loci for Coronary Artery Disease and Detects Independent Signals in Many of the Established Ones (2011) (0)
- Contribution of known genetic variants to increased risk of type-2 diabetes in Indian Asians (2011) (0)
- Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
- Abstract 17979: A Genome-Wide Association Study of Risk of Coronary Artery Disease in European and South Asian Populations (2010) (0)
- Abstract 18321: Analysis of a Consanguineous Cohort to Identify and Characterize Human Knockouts (2015) (0)
- Dietary fatty acids, macronutrient substitutions and food sources and incidence of coronary heart disease: findings from the EPIC-CVD case-cohort study across nine European countries (2021) (0)
- University of Groningen Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (0)
- Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2019) (0)
- Abstract 19434: Smaller Ldl Peak Diameter is Causally Associated With Higher Risk of Coronary Heart Disease (2016) (0)
- Inhibition of MRP1 Induces Fetal Hemoglobin through NRF2 Activation to Protect Human Erythroid Cells from Sickling (2022) (0)
- Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus (2022) (0)
- Accelerating Detection of Disease (ADD) Platform Protocol Summary v2.2 by the ADD Science Task and Finish Group, February 2020 (2020) (0)
- Coronary Artery Disease Candidate Gene Association Study of Coronary Artery Calcification in Chronic Kidney Disease FindingsFromtheCRICStudy ( ChronicRenal Insuf fi ciencyCohort ) (0)
- Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease (2022) (0)
- Age at menopause and the risk of stroke: Observational and Mendelian Randomization analysis in 204,244 postmenopausal women (2023) (0)
- OP-EHEA200971 1..10 (2020) (0)
- The bacteria craze (1999) (0)
- Abstract 16735: Effect of Communicating Phenotypic and Genetic Risk of Coronary Heart Disease Alongside Web-based Lifestyle Advice - The Inform Randomized Clinical Trial (2016) (0)
- Abstract 14267: Integrative Epidemiological and Functional Analyses Identify Protein C as a Novel, Causal Factor in Arterial and Venous Disease (2019) (0)
- Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications (2023) (0)
- A nutritional biomarker score of the Mediterranean diet and incident type 2 diabetes: Integrated analysis of data from the MedLey randomised controlled trial and the EPIC-InterAct case-cohort study (2023) (0)
- A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis (2021) (0)
- New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (0)
- Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis (2020) (0)
- Concordance between genotype and blood group phenotype in the INTERVAL cohort of 50,000 English blood donors (2017) (0)
- Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program (2018) (0)
- Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels (2018) (0)
- Soluble adhesion molecules and coronary heart disease (2002) (0)
- Assessing the causal association of glycine with risk of cardio-metabolic diseases (2019) (0)
- Oct . 02 , 2018 1 GULF WAR ILLNESS Gulf War agents pyridostigmine bromide and permethrin cause hypersensitive nociception that is restored after vagus nerve stimulation (2018) (0)
- Abstract 15464: Serum CXCL12 Levels Decrease Following Acute Myocardial Infarction - Data from the Pakistan Risk of Myocardial Infarction Study (PROMIS) (2011) (0)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
- Lessons from the INTERVAL study – Authors' reply (2018) (0)
- Association of leucocyte telomere length with frailty: a large-scale cross-sectional analysis in UK Biobank (2021) (0)
- Association of MARC1 A165T with metabolic traits. (2020) (0)
- Nature Genetics | Article (2015) (0)
- Foreword to the first edition (2012) (0)
- Paraoxonase polymorphisms and coronary heart disease. Authors' reply (2004) (0)
- Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations (2022) (0)
- Distribution of ancestry in each cohort. (2020) (0)
- Chronic infection and circulating markers of inflammation (2005) (0)
- Genome-Wide Association Identi fi es Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes (2011) (0)
- Abstract 18477: Understanding the Causal Relevance of Apo(a) Isoform Size, Lipoprotein (a) and Oxidized Phospholipids in Coronary Heart Disease (2016) (0)
- Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits (2018) (0)
- Abstract 18399: Higher Plasma Cxcl12 Levels Are Causally Associated With Increased Risk of Coronary Heart Disease (2016) (0)
- Statistics, epidemiology, clinical trials, meta-analyses and evidence-based medicine (2017) (0)
- British Medical Journal (1864) (0)
- Abstract 19506: Relevance of Fibroblast Growth Factor 21 in Cardio-metabolic Diseases (2015) (0)
- Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
- Author Correction: Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease (2018) (0)
- Edinburgh Research Explorer Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes (2018) (0)
- Bahá ' í Scholarship : An examination using citation analysis (2016) (0)
- COMPARISON OF THE ASSOCIATIONS BETWEEN HAEMOSTATIC AND INFLAMMATORY VARIABLES AND CHD RISK: FLETCHER CHALLENGE STUDY (2007) (0)
- 2 Association of Two SNP's at 1p13.3 Locus with LDL-C Levels and Myocardial Infarction in the Pakistani Population(APSC Poster Session 2 (APSC2),Asian Pacific Society of Cardiology,Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society) (2009) (0)
- Genomics of lipid metabolism: Identifying novel causal pathways and new therapeutic targets for reducing risk of coronary heart disease (2016) (0)
- Helicobacter pylori infection. (1997) (0)
- Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease (2020) (0)
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (0)
- Combined Exposure to both Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure with Lifetime Risk of Cardiovascular Disease. JAMA (2019) (0)
- Genetic Contributions to Early and Late Onset Ischemic Stroke (2021) (0)
- Association analyses based on false discovery rate implicate 243 susceptibility loci for coronary artery disease (2017) (0)
- Genetic effects on promoter usage are highly 1 context-specific and contribute to complex traits 2 3 (0)
- Genetic Variants Related to Combined Exposure to both Lower Low- Density Lipoproteins and Lower Systolic Blood Pressure with Lifetime Risk of Cardiovascular Disease. JAMA Network Open, E1-E11 (2019) (0)
- SARS-CoV-2 evolution during treatment of chronic infection (2021) (0)
- Genomic atlas of the human plasma proteome (2018) (0)
- Correction (2017) (0)
- The Malaysian Acute Vascular Events Risk (MAVERIK) study protocol: studying genetic and other determinants of first-ever myocardial infarction in Malaysia (Preprint) (2021) (0)
- Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke (2020) (0)
- Genetic loci for major lipids in Pakistan (2010) (0)
- A catalog of genetic loci associated with kidney function from analyses of a million individuals (2019) (0)
- Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits (2018) (0)
- Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease (2018) (0)
- Azithromycin reduced global tests of systemic levels of inflammatory markers (1999) (0)
- Helicobacter pylori infection (1997) (0)
- Title 1 Distinct genetic architectures for syndromic and nonsyndromic congenital 2 heart defects identified by exome sequencing 3 (2016) (0)
- Abstract 16668: Serum Gamma Glutamyl Transferase and Risk of Coronary Artery Disease: A Causal Assessment by Mendelian Randomization (2013) (0)
- Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes (2018) (0)
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What Schools Are Affiliated With John N. Danesh?
John N. Danesh is affiliated with the following schools: