John F. Burke
#29,116
Most Influential Person Now
American medical researcher
John F. Burke's AcademicInfluence.com Rankings
John F. Burkelaw Degrees
Law
#3005
World Rank
#3767
Historical Rank
#1263
USA Rank
Common Law
#177
World Rank
#191
Historical Rank
#28
USA Rank
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Law
John F. Burke's Degrees
- Bachelors Biology University of California, Berkeley
- Doctorate Medicine Harvard University
- PhD Biomedical Sciences Johns Hopkins University
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Why Is John F. Burke Influential?
(Suggest an Edit or Addition)According to Wikipedia, John F. Burke was an American medical researcher at Harvard University widely known for his co-invention of synthetic skin in 1981, together with Dr. Ioannis V. Yannas. Burke was also widely noted for developing a system of infection control in hospitals and showing that antibiotics given before surgery lower risks of post-operative infections. Burke was head of the Shriners Burns Institute and chief of trauma services at Massachusetts General Hospital, a professor of surgery at Harvard University.
John F. Burke's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Measurement of leucine metabolism in man from a primed, continuous infusion of L-[1-3C]leucine. (1980) (502)
- A specific receptor antagonist for interleukin 1 prevents Escherichia coli‐induced shock in rabbits (1991) (438)
- Glucose metabolism in man: responses to intravenous glucose infusion. (1979) (341)
- Glucose metabolism in severely burned patients. (1979) (320)
- Glucose Requirements Following Burn Injury: Parameters of Optimal Glucose Infusion and Possible Hepatic and Respiratory Abnormalities Following Excessive Glucose Intake (1979) (318)
- Response of Protein and Urea Kinetics in Burn Patients to Different Levels of Protein Intake (1983) (253)
- Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli. (1991) (250)
- Whole-body leucine and lysine metabolism: response to dietary protein intake in young men. (1981) (249)
- Tracer priming the bicarbonate pool. (1978) (222)
- C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha (1988) (219)
- A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis. (1996) (205)
- Investigation of factors determining the optimal glucose infusion rate in total parenteral nutrition. (1980) (204)
- Plasma arginine and citrulline kinetics in adults given adequate and arginine-free diets. (1993) (201)
- C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma. (1987) (200)
- Recovery of 13C in breath from NaH13CO3 infused by gut and vein: effect of feeding. (1989) (200)
- Increased Rates of Whole Body Protein Synthesis and Breakdown in Children Recovering from Burns (1978) (164)
- Quantitative study in vivo of methionine cycle in humans using [methyl-2H3]- and [1-13C]methionine. (1988) (142)
- Dietary arginine uptake by the splanchnic region in adult humans. (1993) (127)
- Interleukin-1 beta in human plasma: optimization of blood collection, plasma extraction, and radioimmunoassay methods. (1988) (126)
- Splanchnic metabolism of dietary arginine in relation to nitric oxide synthesis in normal adult man. (1993) (123)
- Role of interleukin 1 and tumor necrosis factor on energy metabolism in rabbits. (1988) (102)
- Thermodilution right ventricular volume: a novel and better predictor of volume replacement in acute thermal injury. (1981) (88)
- Quantitative role of splanchnic region in leucine metabolism: L-[1-13C,15N]leucine and substrate balance studies. (1990) (88)
- [1-13C; methyl-2H3]methionine kinetics in humans: methionine conservation and cystine sparing. (1990) (87)
- Whole body leucine and lysine metabolism studied with [1-13C]leucine and [alpha-15N]lysine: response in healthy young men given excess energy intake. (1981) (87)
- The realiability of rates of glucose appearance in vivo calculated from constant tracer infusions. (1978) (86)
- Plasma arginine kinetics in adult man: response to an arginine-free diet. (1994) (83)
- Whole Body Arginine Metabolism and Nitric Oxide Synthesis in Newborns with Persistent Pulmonary Hypertension (1995) (82)
- Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells. (1998) (76)
- Plasma arginine and leucine kinetics and urea production rates in burn patients. (1995) (75)
- Right Ventricular Dysfunction in Acute Thermal Injury (1980) (71)
- Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits (1993) (71)
- Measurement of plasma free fatty acid turnover and oxidation using [1-13C]palmitic acid. (1980) (71)
- Preferential Activation and Depletion of the Alternative Complement Pathway by Burn Injury (1983) (65)
- Alternative complement pathway activation increases mortality in a model of burn injury in mice. (1982) (63)
- Whole-body protein synthesis and breakdown rates in children before and after reconstructive surgery of the skin. (1978) (62)
- Measured and predicted calorie requirements of adults during recovery from severe burn trauma. (1989) (62)
- Relations among arginine, citrulline, ornithine, and leucine kinetics in adult burn patients. (1995) (59)
- Maximal parenteral glucose oxidation in hypermetabolic young children: a stable isotope study. (1998) (59)
- The plasma flux and oxidation rate of ornithine adaptively decline with restricted arginine intake. (1994) (59)
- Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia. (1994) (56)
- Splanchnic and whole body L-[1-13C,15N]leucine kinetics in relation to enteral and parenteral amino acid supply. (1992) (55)
- Quantitative contribution by skeletal muscle to elevated rates of whole-body protein breakdown in burned children as measured by N tau-methylhistidine output. (1978) (54)
- Quantitative aspects of interorgan relationships among arginine and citrulline metabolism. (1996) (54)
- Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans. (1992) (53)
- Whole Body Protein Synthesis in Relation to Basal Energy Expenditure in Healthy Children and in Children Recovering from Burn Injury (1978) (51)
- Glucose and lactate metabolism in experimental septic shock. (1978) (50)
- Pulmonary artery catheterization and thermodilution cardiac output determination in the management of critically burned patients (1978) (50)
- Kinetics of plasma arginine and leucine in pediatric burn patients. (1996) (49)
- Phenylalanine and Tyrosine Kinetics in Critically Ill Children with Sepsis (1994) (45)
- A Kinetic Study of Leucine Metabolism in Severely Burned Patients Comparison Between a Conventional and Branched‐Chain Amino Acid‐Enriched Nutritional Therapy (1988) (45)
- Quantitative aspects of glycine and alanine nitrogen metabolism in postabsorptive young men: effects of level of nitrogen and dispensable amino acid intake. (1985) (44)
- Right ventricular function and pulmonary hemodynamics during dopamine infusion in burned patients. (1986) (44)
- Proline metabolism in adult male burned patients and healthy control subjects. (1991) (43)
- Determination of the isotope enrichment of one or a mixture of two stable labelled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies. (1993) (42)
- Impact of C-reactive protein (CRP) on surfactant function. (1989) (41)
- Structural and functional studies on hemoglobin Bethesda (α2β2145 His), a variant associated with compensatory erythrocytosis (1972) (40)
- Coagulation of Whole Blood Stimulates Interleukin-1β Gene Expression (1995) (40)
- Effect of burn trauma on glucose turnover, oxidation, and recycling in guinea pigs. (1977) (40)
- Determination of 4-hydroxyproline in collagen by gas chromatography/mass spectrometry. (1990) (39)
- Synthesis and degradation rates of collagens in vivo in whole skin of rats, studied with 1802 labelling. (1986) (39)
- Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells. (1997) (38)
- A kinetic study of L-2H3-methyl-1-13C-methionine in patients with severe burn injury. (1993) (36)
- Whole-body lysine flux in young adult men: effects of reduced total protein and of lysine intake. (1980) (35)
- Altered interleukin-1 and tumor necrosis factor production and secretion during pyrogenic tolerance to LPS in rabbits. (1994) (35)
- Cytokines, Acute Phase Proteins, and Tissue Injury (1990) (35)
- Plasma proline kinetics and the regulation of proline synthesis in man. (1987) (33)
- Dose responsive effects of PDGF-BB, PDGF-AA, EGF, and bFGF on granulation tissue in a guinea pig partial thickness skin excision model. (1993) (32)
- Sialic Acid-deficient α1-Acid Glycoprotein produced in Certain Pathological States (1964) (31)
- A rabbit model for metabolic studies after burn injury. (1998) (29)
- Interleukin-1 upregulates anaphylatoxin receptors on mononuclear cells. (2004) (29)
- Effect of glucose infusion on glucose and lactate metabolism in normal and burned guinea pigs. (1978) (29)
- Water metabolism and antidiuretic hormone (ADH) response following thermal injury. (1980) (28)
- Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine. (1996) (28)
- Comparative evaluation of the quantitative utilization of parenterally and enterally administered leucine and L-[1-13C,15N]leucine within the whole body and the splanchnic region. (1995) (25)
- Extrapulmonary factors influencing the ratio of arterial oxygen tension to inspired oxygen concentration in burn patients (1979) (23)
- Pulmonary artery catheterization and thermodilution cardiac output determination in the management of critically burned patients. (1979) (23)
- The effects of UVB plus calcipotriol on systemic calcium homeostasis in patients with chronic plaque psoriasis (1997) (23)
- The constancy of the alpha-1-acid glycoprotein variants of normal adults under conditions of severe stress. (1966) (22)
- Gastric mucosal lesions after burn injury: relationship to H+ back-diffusion and the microcirculation. (1978) (22)
- TCA cycle flux estimates from NMR- and GC-MS-determined [13C]glutamate isotopomers in liver. (1997) (21)
- The reliability of rates of glucose appearance in vivo calculated from single tracer injections. (1979) (21)
- Synthesis and degradation of collagens in skin of healthy and protein-malnourished rats in vivo, studied by 18O2 labelling. (1988) (20)
- Insulin resistance in peripheral tissues after a burn injury. (1979) (19)
- Prediction of total urinary nitrogen from urea nitrogen for burned patients. (1985) (18)
- Glucose kinetics and responsiveness to insulin in the rat injured by burn. (1978) (18)
- Lactate oxidation in perfused rat lung. (1979) (17)
- Coagulation of whole blood stimulates interleukin-1 beta gene expression. (1995) (16)
- Inhibition of Human Neutrophil and Pseudomonas Elastases by the Amyloid P‐Component: A Constituent of Elastic Fibers and Amyloid Deposits (1988) (16)
- The effect of antibody to L-phenylalanine mustard conjugate on malignant cells selectively marked through "early inflammatory-like" vascular permeability. (1966) (15)
- Quantitative study in vivo of methionine cycle in humans using (methyl-/sup 2/H/sub 3/)- and (1-/sup 13/C)methionine (1988) (14)
- Fallibility of the intravenous glucose tolerance test as a measure of endogenous glucose turnover. (1978) (14)
- Increased glucose production following neurotensin administration. (1978) (13)
- Somatostatin infusion inhibits glucose production in burn patients. (1982) (13)
- 99Tcm-labelled meso-HMPAO and glutathione content of human lung tumours. (1989) (13)
- Development and ultrastructure of a microsporidian parasite in midgut cells of the larch sawfly, Pristiphora erichsonii (Hymenoptera: Tenthredinidae) (1982) (11)
- Closed-circuit metabolic system with multiple applications. (1986) (11)
- Gas chromatography-mass spectrometry determination of 18O2 in 18O-labelled 4-hydroxyproline for measurement of collagen synthesis and intracellular degradation. (1993) (10)
- Intestinal production of interleukin-1 alpha during endotoxemia in the mouse. (1993) (10)
- The fate of a glucose infusion in fasting and fed guinea pigs: glucose oxidation rates and the distribution of glucose in liver, muscle, and adipose tissue. (1980) (10)
- Induced immunologic response to tumors. (1969) (10)
- Is there a selective increase in pulmonary capillary permeability following cutaneous burns? (1979) (10)
- Urea, glucose and alanine kinetics in man: effects of glucose infusion. (1982) (10)
- The measurement of glucose turnover and oxidation using radioactive and stable isotopes. (1983) (10)
- Energy intake and whole body protein dynamics in man. (1981) (10)
- Interleukin-1 pretreatment protects against endotoxin-induced hypotension in rabbits: association with decreased tumor necrosis factor levels. (1993) (10)
- Influence of insulin and palmitic acid concentration on pulmonary surfactant synthesis. (1979) (9)
- Postburn hypermetabolism: relation to evaporative heat loss and catecholamine level. (1975) (9)
- Glucose and fatty acid kinetics in fasted rats: effects of previous protein intake. (1982) (8)
- Enhanced amino acid uptake in both skeletal muscle and liver by burn plasma in rats. (1994) (8)
- Changes with age in the metabolism of sulfated glycosaminoglycans in guinea pig cardiac valves. (1970) (7)
- Relative and absolute changes in soluble and insoluble collagen pool size in skin during normal growth and with dietary protein restriction in rats. (1987) (7)
- Endotoxin suppresses surfactant synthesis in cultured rat lung cells. (1989) (7)
- Adequacy of a modular tube feeding diet for burned patients. (1986) (7)
- Ventricular volume and ejection fraction in the diagnosis of the aetiology of low cardiac output in burned patients (1986) (7)
- Uptake of alpha-aminoisobutyric acid and cycloleucine on skeletal muscles in burned rats. (1992) (5)
- An in vitro model of the wound microenvironment: local phagocytic cell abnormalities associated with in situ complement activation. (1987) (5)
- SURVEY OF PATHOGENS IN THE LARGE ASPEN TORTRIX, CHORISTONEURA CONFLICTANA (LEPIDOPTERA: TORTRICIDAE), IN ONTARIO AND BRITISH COLUMBIA WITH PARTICULAR REFERENCE TO GRANULOSIS VIRUS (1982) (5)
- Dietary compliance for pediatric burned patients. (1984) (5)
- Weight maintenance in pediatric burned patients. (1986) (4)
- Effect of food intake on hypermetabolic response to burn injury in guinea pigs. (1980) (4)
- Experimental sepsis and glucose metabolism: time course of response. (1977) (4)
- A general model for analysis of the tricarboxylic acid cycle with use of [13C]glutamate isotopomer measurements. (1994) (4)
- Wound healing. (1999) (4)
- Wound Healing (1999) (4)
- The rat lung organotypic culture: an in vitro model for studying surfactant metabolism abnormalities. (1991) (3)
- Structural and functional studies on hemoglobin Bethesda (alpha2beta2 145His), a varient associated with compensatory erythrocytosis. (1972) (3)
- Interrelationships between glucose and free fatty acid (FFA) metabolism during infusion of glucose and Intralipid. (1979) (2)
- Microderivatization of 4-[18O]hydroxyproline and quantitation with a benchtop mass spectrometer. (1991) (2)
- Nitrogen sparing effect of a branched-chain amino acid infusion during an acute fast in guinea pigs. (1978) (1)
- Physiological assessments of occupational activities (2002) (1)
- Quantitative role of the splanchnic bed in whole body leucine metabolism (1986) (1)
- Metabolic and clinical considerations in an unusual patient with 35% BSA deep partial-thickness thermal injury. (1977) (1)
- Techniques for investigating substrate metabolism in patients. (1981) (1)
- Increased dense erythrocytes in flame-burned patients. (2013) (1)
- LOW DOSE DOPAMINE EFFECTS (β EFFECTS) ON RIGHT VENTRICULAR FUNCTION AND PULMONARY CIPULATION IN BUPNED PATIENTS (1983) (0)
- 70. Suppression endothelial-vasculärer Abstoßungs-phänomene durch ALS (1971) (0)
- PROTEIN SYNTHESIS AND CATABOLISM IN HEALTHY CHILDREN, BEFORE AND AFTER ELECTIVE SURGERY (1977) (0)
- Different Insulin Regimens and Diabetic Control (1980) (0)
- INTERLEUKIN-1α TISSUE LEVELS DURING ENDOTOXEMIA IN THE RAT.: 97 (1997) (0)
- A microradiographic study of developing staphylococcal inflammation using ultra-soft roentgen rays. (1961) (0)
- Human C3a enhances tumor necrosis factor, interleukin-1, and interleukin-6 production in endotoxin-stimulated human PBMC (1994) (0)
- SIALIC ACID-DEFICIENT ALPHA-1-ACID GLYCOPROTEIN PRODUCED IN CERTAIN PATHOLOGICAL STATES. (1964) (0)
- EVALUATION OF THE ROLE OF CATECHOLAMINES IN ALTERING GLUCOSE METABOLISM AFTER INJURY (1981) (0)
- INTERLEUKIN‐1&agr; TISSUE LEVELS DURING ENDOTOXEMIA IN THE RAT.: 97 (1997) (0)
- Fibrinogen Heterogeneity, Fibrinolysis and Blood Coagulation in Burned Patients (1977) (0)
- Electrophysiological Responses to Maximum Isometric Exercise. (1971) (0)
- Splanchnic metabolism ofdietary arginine inrelation tonitric oxide synthesis innormaladult man (nitrate/metabolism/diet) (1993) (0)
- Measurement of interleukin-1α levels in rats following burn injury using a radioimmunoassay for rat IL-1α (1991) (0)
- Effect of treatment with L-phenylalanine mustard and antibody on survival time of mice with intracerebral ependymoblastomas. (1972) (0)
- The effect of treatment with L–phenylalanine mustard and L–phenylalanine mustard antibody on the survival time of mice with intracerebral ependymoblastomas (1973) (0)
- Induced Immunologie Response to Tumors (2006) (0)
- Synthesis and degradation of collagens in skin of healthy and protein-malnourished rats in vivo , studied by 1802 labelling (2005) (0)
- Insulin and glucose kinetics following surgery. (1980) (0)
- Studies onGenetic Male-Sterile Soybeans' V.EFFECTSOF MALE-STERILITY ON THE FUNCTIONAND GLYCEROLIPIDCOMPOSITIONOF CHLOROPLASTTHYLAKOIDS (1987) (0)
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