John I. Gallin

Q: What Schools Are Affiliated With John I. Gallin

John I. Gallin is affiliated with the following schools: Cornell University, Sapienza University of Rome, Columbia University

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John I. Gallin

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Philosophy

John I. Gallin's Degrees

Doctorate Medicine Columbia University

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John I. Gallin's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Inflammation: Basic Principles and Clinical Correlates (1992) (1913)
Chronic Granulomatous Disease: Report on a National Registry of 368 Patients (2000) (1583)
STAT3 mutations in the hyper-IgE syndrome. (2007) (1092)
Genetic, biochemical, and clinical features of chronic granulomatous disease. (2000) (883)
Current concepts: immunology. Neutrophils in human diseases. (1987) (805)
Hyper-IgE syndrome with recurrent infections--an autosomal dominant multisystem disorder. (1999) (729)
A controlled trial of interferon gamma to prevent infection in chronic granulomatous disease. The International Chronic Granulomatous Disease Cooperative Study Group. (1991) (671)
The p47phox mouse knock-out model of chronic granulomatous disease (1995) (491)
Residual NADPH oxidase and survival in chronic granulomatous disease. (2010) (467)
Selective predisposition to bacterial infections in IRAK-4–deficient children: IRAK-4–dependent TLRs are otherwise redundant in protective immunity (2007) (396)
Immunodeficiency diseases caused by defects in phagocytes. (2000) (389)
Genetic linkage of hyper-IgE syndrome to chromosome 4. (1999) (372)
Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency (2010) (372)
Serum lipids in infection. (1969) (359)
Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease. (1997) (352)
Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src. (1990) (349)
Laboratory Manual of Neutrophil Function (1986) (329)
Gastrointestinal involvement in chronic granulomatous disease. (2004) (326)
Itraconazole to prevent fungal infections in chronic granulomatous disease. (2003) (323)
Granulocyte chemotaxis: an improved in vitro assay employing 51 Cr-labeled granulocytes. (1973) (310)
Treatment of refractory disseminated nontuberculous mycobacterial infection with interferon gamma. A preliminary report. (1994) (309)
THE REGULATORY ROLE OF DIVALENT CATIONS IN HUMAN GRANULOCYTE CHEMOTAXIS (1974) (298)
Distinct Mutations in IRAK-4 Confer Hyporesponsiveness to Lipopolysaccharide and Interleukin-1 in a Patient with Recurrent Bacterial Infections (2003) (292)
An inherited abnormality of neutrophil adhesion. Its genetic transmission and its association with a missing protein. (1980) (290)
Common severe infections in chronic granulomatous disease. (2015) (289)
Two forms of autosomal chronic granulomatous disease lack distinct neutrophil cytosol factors. (1988) (287)
Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease. (1989) (285)
Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils. (1985) (276)
Secretory responses of human neutrophils: exocytosis of specific (secondary) granules by human neutrophils during adherence in vitro and during exudation in vivo. (1979) (276)
Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a T-cell-depleted hematopoietic allograft. (2001) (272)
Histamine type I receptor occupancy increases endothelial cytosolic calcium, reduces F-actin, and promotes albumin diffusion across cultured endothelial monolayers (1986) (266)
The selective eosinophil chemotactic activity of histamine (1975) (248)
Aspergillus nidulans Infection in Chronic Granulomatous Disease (1998) (244)
Genetic variants of chronic granulomatous disease: prevalence of deficiencies of two cytosolic components of the NADPH oxidase system. (1989) (240)
Hematologically important mutations: X-linked chronic granulomatous disease (third update). (1997) (234)
Trimethoprim-sulfamethoxazole prophylaxis in the management of chronic granulomatous disease. (1990) (234)
Chronic granulomatous disease as a risk factor for autoimmune disease. (2008) (219)
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. (2008) (219)
An immune-based biomarker signature is associated with mortality in COVID-19 patients (2020) (216)
The Hyperimmunoglobulin E Recurrent‐Infection (Job's) Syndrome: A REVIEW OF THE NIH EXPERIENCE AND THE LITERATURE (1983) (212)
Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone (2007) (211)
Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis. (1984) (210)
IL-4 inhibits superoxide production by human mononuclear phagocytes. (1990) (209)
Mechanism for the inflammatory response in primate lungs. Demonstration and partial characterization of an alveolar macrophage-derived chemotactic factor with preferential activity for polymorphonuclear leukocytes. (1977) (202)
Human leukocytic pyrogen induces release of specific granule contents from human neutrophils. (1978) (199)
Neutrophil-specific Granule Deficiency Results from a Novel Mutation with Loss of Function of the Transcription Factor CCAAT/Enhancer Binding Protein ε (1999) (199)
Human Polymorphonuclear Leukocytes Inhibit Aspergillus fumigatus Conidial Growth by Lactoferrin-Mediated Iron Depletion1 (2007) (190)
Use of lipophilic probes of membrane potential to assess human neutrophil activation. Abnormality in chronic granulomatous disease. (1980) (189)
Recent Advances in Chronic Granulomatous Disease (1983) (186)
Long-Term Interferon-γ Therapy for Patients with Chronic Granulomatous Disease (2004) (186)
Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency. (1988) (184)
Role of secretory events in modulating human neutrophil chemotaxis. (1978) (182)
Hematologically important mutations: the autosomal recessive forms of chronic granulomatous disease (second update). (2000) (170)
Brief report: genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne). (2012) (168)
Recombinant human interferon-gamma reconstitutes defective phagocyte function in patients with chronic granulomatous disease of childhood. (1988) (160)
Neutrophil granules in health and disease. (1986) (158)
Increased circulating cytokines, cytokine antagonists, and E-selectin after intravenous administration of endotoxin in humans. (1995) (158)
Fletcher factor deficiency. A diminished rate of Hageman factor activation caused by absence of prekallikrein with abnormalities of coagulation, fibrinolysis, chemotactic activity, and kinin generation. (1974) (151)
Degranulating stimuli increase the availability of receptors on human neutrophils for the chemoattractant f-met-leu-phe. (1980) (149)
Correlation of human neutrophil secretion, chemoattractant receptor mobilization, and enhanced functional capacity. (1982) (148)
Diffusion of extracellular hydrogen peroxide into intracellular compartments of human neutrophils. Studies utilizing the inactivation of myeloperoxidase by hydrogen peroxide and azide. (1985) (148)
Exudation primes human and guinea pig neutrophils for subsequent responsiveness to the chemotactic peptide N-formylmethionylleucylphenylalanine and increases complement component C3bi receptor expression. (1986) (144)
Normal and deficient neutrophils can cooperate to damage Aspergillus fumigatus hyphae. (1990) (143)
Fulminant mulch pneumonitis: an emergency presentation of chronic granulomatous disease. (2007) (140)
Interaction of leukocyte chemotactic factors with the cell surface. I. Chemotactic factor-induced changes in human granulocyte surface charge. (1975) (136)
Interferon- in the Management of Infectious Diseases (1995) (131)
Corticosteroids in treatment of obstructive lesions of chronic granulomatous disease. (1987) (131)
Human neutrophil heterogeneity exists, but is it meaningful? (1984) (130)
The differential mobilization of human neutrophil granules. Effects of phorbol myristate acetate and ionophore A23187. (1977) (128)
Separation and functional characterization of human neutrophil subpopulations. (1978) (127)
Hepatic Abscess in Patients With Chronic Granulomatous Disease (2002) (124)
In vivo interferon-gamma therapy augments the in vitro ability of chronic granulomatous disease neutrophils to damage Aspergillus hyphae. (1991) (121)
B cell lines as models for inherited phagocytic diseases: abnormal superoxide generation in chronic granulomatous disease and giant granules in Chediak-Higashi syndrome. (1984) (120)
Regulation of immunoglobulin production in hyperimmunoglobulin E recurrent-infection syndrome by interferon gamma. (1989) (119)
Human neutrophil-specific granule deficiency: a model to assess the role of neutrophil-specific granules in the evolution of the inflammatory response. (1982) (118)
Histamine modulation of eosinophil migration. (1977) (118)
Evidence for a functional cytoplasmic domain of phagocyte oxidase cytochrome b558. (1990) (115)
Genes Differentially Expressed in Conidia and Hyphae of Aspergillus fumigatus upon Exposure to Human Neutrophils (2008) (115)
X‐linked carriers of chronic granulomatous disease: Illness, lyonization, and stability (2018) (113)
Degranulating stimuli decrease the neagative surface charge and increase the adhesiveness of human neutrophils. (1980) (110)
Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils. (1986) (110)
Stimulation of neutrophil oxygen-dependent metabolism by human leukocytic pyrogen. (1979) (109)
Disorders of phagocyte chemotaxis. (1980) (107)
A functional differentiation of human neutrophil granules: generation of C5a by a specific (secondary) granule product and inactivation of C5a by azurophil (primary) granule products. (1977) (105)
Inhibition of Human Neutrophil IL-8 Production by Hydrogen Peroxide and Dysregulation in Chronic Granulomatous Disease1 (2005) (103)
Ca2+-dependent production and release of IL-8 in human neutrophils. (1998) (100)
Endotoxin and IL-1 hyporesponsiveness in a patient with recurrent bacterial infections. (1997) (100)
Long-term interferon-gamma therapy for patients with chronic granulomatous disease. (2004) (98)
Leukocyte chemotaxis : methods, physiology, and clinical implications (1978) (97)
Human neutrophil heterogeneity identified using flow microfluorometry to monitor membrane potential. (1981) (97)
Alloimmunization after granulocyte transfusions (1996) (97)
Oxidative killing of Aspergillus fumigatus proceeds by parallel myeloperoxidase-dependent and -independent pathways (1987) (96)
Biochemistry of phagocyte chemotaxis. (1979) (96)
Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus (2007) (94)
Delayed eruption of permanent teeth in hyperimmunoglobulinemia E recurrent infection syndrome. (2000) (93)
Histamine modulation of human neutrophil oxidative metabolism, locomotion, degranulation, and membrane potential changes. (1983) (93)
Human neutrophils contain an intracellular pool of putative receptors for the chemoattractant N-formyl-methionyl-leucyl-phenylalanine. (1983) (92)
Dynamics of the cellular and humoral components of the inflammatory response elicited in skin blisters in humans. (1992) (92)
Deactivation of human neutrophil chemotaxis by chemoattractants: effect on receptors for the chemotactic factor f-Met-Leu-Phe. (1981) (91)
Effect of prophylactic colchicine therapy on leukocyte function in patients with familial Mediterranean fever. (1976) (90)
IgE antibodies to Staphylococcus aureus and Candida albicans in patients with the syndrome of hyperimmunoglobulin E and recurrent infections. (1980) (89)
Neutrophil degranulation and abnormal chemotaxis after thermal injury. (1980) (88)
Nocardia infection in chronic granulomatous disease. (2002) (87)
Immunoglobulins in the hyperimmunoglobulin E and recurrent infection (Job's) syndrome. Deficiency of anti-Staphylococcus aureus immunoglobulin A. (1985) (87)
Disorders of phagocyte function. (1987) (82)
Thioglycollate peritonitis in mice lacking C5, 5‐lipoxygenase, or p47phox: complement, leukotrienes, and reactive oxidants in acute inflammation (2002) (81)
Gastrointestinal Histopathology in Chronic Granulomatous Disease: A Study of 87 Patients (2013) (81)
Hepatic abnormalities in patients with chronic granulomatous disease (2007) (81)
Cognitive function in patients with chronic granulomatous disease: a preliminary report. (2004) (81)
Cytoskeletal abnormalities and neutrophil dysfunction in WDR1 deficiency. (2016) (80)
Peripheral blood progenitors as a target for genetic correction of p47phox-deficient chronic granulomatous disease. (1993) (80)
Abnormal phagocyte chemotaxis: pathophysiology, clinical manifestations, and management of patients. (1981) (79)
Effects of levamisole on normal and abnormal leukocyte locomotion. (1977) (79)
Use of an X-linked human neutrophil marker to estimate timing of lyonization and size of the dividing stem cell pool. (1985) (77)
Rapid method for isolation of normal human peripheral blood eosinophils on discontinuous Percoll gradients and comparison with neutrophils (1985) (76)
Successful treatment of Paecilomyces varioti infection in a patient with chronic granulomatous disease and a review of Paecilomyces species infections. (1992) (76)
The urological manifestations of chronic granulomatous disease. (1992) (76)
Hepatic involvement and portal hypertension predict mortality in chronic granulomatous disease. (2008) (75)
Esophageal cryptococcosis in a patient with the hyperimmunoglobulin E-recurrent infection (Job's) syndrome (1984) (75)
Granule Deficiency: A Model to Assess the Role of Neutrophil-Specific Granules in the Evolution of the Inflammatory Response (1982) (74)
Cytochrome b translocation to human neutrophil plasma membranes and superoxide release. Differential effects of N-formylmethionylleucylphenylalanine, phorbol myristate acetate, and A23187. (1985) (74)
Chemotactic activity in dialyzable transfer factor. (1974) (74)
Neutrophil specific granule deficiency. (1985) (74)
Successful treatment of systemic Exophiala dermatitidis infection in a patient with chronic granulomatous disease. (1992) (74)
Kinetic analysis of chemotactic factor generation in human serum via activation of the classical and alternate complement pathways. (1975) (73)
CD34+ peripheral blood progenitors as a target for genetic correction of the two flavocytochrome b558 defective forms of chronic granulomatous disease (1994) (73)
Inherited p40phox deficiency differs from classic chronic granulomatous disease (2018) (72)
Severe Burkholderia (Pseudomonas) gladioli infection in chronic granulomatous disease: report of two successfully treated cases. (1995) (72)
Burkholderia pseudomallei infection in a Puerto Rican patient with chronic granulomatous disease: case report and review of occurrences in the Americas. (1998) (71)
Gingivitis and oral ulceration in patients with neutrophil dysfunction. (1985) (70)
Functional abnormalities of human neutrophils collected by continuous flow filtration leukopheresis. (1975) (70)
Update on chronic granulomatous diseases of childhood. Immunotherapy and potential for gene therapy. (1990) (68)
Metabolism of immunoglobulin E in patients with markedly elevated serum immunoglobulin E levels. (1987) (67)
Principles and Practice of Clinical Research (2002) (66)
An AAVS1-targeted minigene platform for correction of iPSCs from all five types of chronic granulomatous disease. (2015) (66)
Comparison of indirect probes of membrane potential utilized in studies of human neutrophils (1983) (64)
Antifungal Activities of Natural and Synthetic Iron Chelators Alone and in Combination with Azole and Polyene Antibiotics against Aspergillus fumigatus (2009) (62)
Bronchoalveolar lavage analysis in Wegener's granulomatosis. A method to study disease pathogenesis. (1991) (62)
Subcellular localization of Gi alpha in human neutrophils. (1988) (61)
Mononuclear cell chemotactic activity of kallikrein and plasminogen activator and its inhibition by C1 inhibitor and alpha 2-macroglobulin. (1974) (61)
Fibrinogen Induces IL-8 Synthesis in Human Neutrophils Stimulated with Formyl-Methionyl-Leucyl-Phenylalanine or Leukotriene B41 (2001) (61)
Leukocyte transfusions in chronic granulomatous disease: persistence of transfused leukocytes in sputum. (1982) (61)
Adaptation of human neutrophil responsiveness to the chemoattractant N-formylmethionylleucylphenylalanine. Heterogeneity and/or negative cooperative interaction of receptors. (1982) (60)
Selective defect in myeloid cell lactoferrin gene expression in neutrophil specific granule deficiency. (1989) (59)
Localization of submembranous cations to the leading end of human neutrophils during chemotaxis (1979) (58)
Cutting Edge: Expression of IL-1 Receptor-Associated Kinase-4 (IRAK-4) Proteins with Mutations Identified in a Patient with Recurrent Bacterial Infections Alters Normal IRAK-4 Interaction with Components of the IL-1 Receptor Complex1 (2005) (57)
Cryptococcosis of the colon resembling Crohn's disease in a patient with the hyperimmunoglobulinemia E-recurrent infection (Job's) syndrome. (1988) (56)
Polymorphonuclear leukocyte and monocyte chemoattractants produced by human fibroblasts. (1979) (56)
Skeletal involvement in children who have chronic granulomatous disease. (1991) (56)
Tryptophan/kynurenine metabolism in human leukocytes is independent of superoxide and is fully maintained in chronic granulomatous disease. (2010) (55)
Induction of Human Monocyte Interleukin (IL)-8 by Fibrinogen through the Toll-Like Receptor Pathway (2007) (55)
Neutrophil specific granules: a fuse that ignites the inflammatory response. (1984) (54)
Gastrointestinal Features of Chronic Granulomatous Disease Found During Endoscopy. (2016) (54)
Abnormal adherence-related functions of neutrophils, monocytes, and Epstein-Barr virus-transformed B cells in a patient with C3bi receptor deficiency. (1985) (52)
Auranofin affects early events in human polymorphonuclear neutrophil activation by receptor-mediated stimuli. (1984) (52)
Increased cell-associated IL-8 in human exudative and A23187-treated peripheral blood neutrophils. (1995) (52)
Reinfection, rather than persistent infection, in patients with chronic granulomatous disease. (2003) (51)
Mononuclear cells from patients with the hyperimmunoglobulin E-recurrent infection syndrome produce an inhibitor of leukocyte chemotaxis. (1982) (51)
NADPH Oxidase-2 and Atherothrombosis: Insight From Chronic Granulomatous Disease. (2017) (51)
Spleen-derived mononuclear cell chemotactic factor in malaria infections: a possible mechanism for splenic macrophage accumulation. (1977) (51)
An antibody binding to human neutrophils demonstrates antigenic heterogeneity detected early in myeloid maturation which correlates with functional heterogeneity of mature neutrophils. (1985) (50)
Leukocyte adherence-related glycoproteins LFA-1, Mo1, and p150,95: a new group of monoclonal antibodies, a new disease, and a possible opportunity to understand the molecular basis of leukocyte adherence. (1985) (49)
Interferon-gamma in the management of infectious diseases. (1995) (49)
Abnormal regulation of inflammatory skin responses in male patients with chronic granulomatous disease (1983) (47)
Intermediate phenotypes in patients with autosomal dominant hyper-IgE syndrome caused by somatic mosaicism. (2013) (47)
Impaired Priming and Activation of the Neutrophil NADPH Oxidase in Patients with IRAK4 or NEMO Deficiency1 (2009) (47)
Changes in the structural and functional properties of human eosinophils during experimental hookworm infection. (1986) (44)
Surgical pathology of the lung in chronic granulomatous disease. (1994) (43)
An in vitro study of neutrophils obtained from the normal gingival sulcus. (1982) (42)
Effects of taxol on human neutrophils. (1982) (42)
Rapid method for isolation of normal human peripheral blood eosinophils on discontinuous Percoll gradients and comparison with neutrophils. (1985) (41)
Regulation of immunoglobulin production in hyper-IgE (Job's) syndrome. (1999) (41)
IFN-gamma is effective in reducing infections in the mouse model of chronic granulomatous disease (CGD). (2001) (41)
Levamisole is inferior to placebo in the hyperimmunoglobulin E recurrent-infection (Job's) syndrome. (1982) (40)
Mutational analysis of patients with p47-phox-deficient chronic granulomatous disease: The significance of recombination events between the p47-phox gene (NCF1) and its highly homologous pseudogenes. (2001) (40)
Lessons about the pathogenesis and management of aspergillosis from studies in chronic granulomatous disease. (2007) (40)
Interferon-γ in the Management of Chronic Granulomatous Disease (1991) (40)
Loss of L-selectin (CD62L) on human neutrophils following exudation in vivo. (1995) (39)
Differential binding of chemoattractant peptide to subpopulations of human neutrophils. (1984) (38)
Chronic granulomatous disease of childhood. An unusual case of infection with Aspergillus nidulans var. echinulatus. (1988) (38)
The effect of hemodialysis and C5a des arg on neutrophil subpopulations (1980) (38)
Phagocyte defects. (1986) (37)
Acremonium strictum-related pulmonary infection in a patient with chronic granulomatous disease. (1984) (37)
The relationship between alloimmunization and posttransfusion granulocyte survival: experience in a chronic granulomatous disease cohort (2011) (36)
Lysis of tumor cells by human blood monocytes by a mechanism independent of activation of the oxidative burst. (1985) (35)
Recurrent severe infections in a child with abnormal leukocyte function: possible relationship to increased microtubule assembly. (1978) (35)
Tubulin tyrosinolation in human polymorphonuclear leukocytes: studies in normal subjects and in patients with the Chediak-Higashi syndrome (1982) (35)
NIH conference. Recent advances in chronic granulomatous disease. (1983) (35)
Selective defect in human neutrophil superoxide anion generation elicited by the chemoattractant N-formylmethionylleucylphenylalanine in pregnancy. (1983) (35)
Analphoid marker chromosome in a patient with hyper-IgE syndrome, autism, and mild mental retardation (1999) (34)
Assessment of Atherosclerosis in Chronic Granulomatous Disease (2014) (34)
Secretagogue modulation of the response of human neutrophils to chemoattractants: studies with a membrane potential sensitive cyanine dye. (1980) (32)
Formyl peptide leukocyte chemoattractant uptake and release by cultured human umbilical vein endothelial cells. (1987) (32)
Organelle-depleted human neutrophil cytoplasts used to study fmet-leu-phe receptor modulation and cell function. (1984) (31)
Increasing extracellular potassium causes calcium-dependent shape change and facilitates concanavalin A capping in human neutrophils. (1984) (31)
Radiation effects on cultured human monocytes and on monocyte-derived macrophages. (1984) (30)
Surgical management of pulmonary infections in chronic granulomatous disease of childhood. (1993) (29)
Treatment of infectious and neoplastic diseases with transfer factor. (1974) (28)
Effects of vitamin K on human neutrophil function. (1982) (28)
Mobilization and adaptation of human neutrophil chemoattractant fMet-Leu-Phe receptors. (1984) (28)
Treatment with intralesional granulocyte instillations and interferon-gamma for a patient with chronic granulomatous disease and multiple hepatic abscesses. (1994) (27)
Monocytes accumulate on Rebuck skin window coverslips but not in skin chamber fluid. A comparative evaluation of two in vivo migration models. (1987) (27)
Outcomes From the NIH Clinical Research Training Program: A Mentored Research Experience to Enhance Career Development of Clinician–Scientists (2016) (26)
Two inhibitors of neutrophil chemotaxis are produced by hyperimmunoglobulin E recurrent infection syndrome mononuclear cells exposed to heat-killed staphylococci (1983) (26)
Inhibition of neutrophil Fc receptor function by cotricosteroids. (1978) (26)
Esophageal cryptococcosis in a patient with the hyperimmunoglobulin E-recurrent infection (Job's) syndrome. (1984) (26)
The Changing Paradigm of Management of Liver Abscesses in Chronic Granulomatous Disease (2018) (25)
Suppression of cellular immune responses following transfer factor: report of a case. (1975) (25)
Basic science: Bedrock of progress. (2016) (25)
Suppurative cutaneous granulomata caused by Microascus cinereus in a patient with chronic granulomatous disease. (1995) (24)
A neutrophil membrane marker reveals two groups of chronic myelogenous leukemia and its absence may be a marker of disease progression. (1986) (24)
Mobilization and exocytosis of specific (secondary) granules by human neutrophils during adherence to nylon wood in filtration leukapheresis (FL). (1978) (24)
Delineation of the phagocyte NADPH oxidase through studies of chronic granulomatous diseases of childhood (1992) (24)
Evidence for oxidative phosphorylation in Streptococcusfaecalis (1964) (24)
Retroviral expression of recombinant p47phox protein by Epstein-Barr virus-transformed B lymphocytes from a patient with autosomal chronic granulomatous disease. (1992) (24)
Evaluation of the patient with recurrent bacterial infections. (1998) (24)
Interaction of chemotactic factors with human polymorphonuclear leukocytes: Studies using a membrane potential-sensitive cyanine dye (2005) (24)
Invasive infection with Sarcinosporon inkin in a patient with chronic granulomatous disease. (1990) (24)
CD34+ peripheral blood progenitors as a target for genetic correction of the two flavocytochrome b558 defective forms of chronic granulomatous disease. (1994) (23)
Visceral botryomycosis caused by Neisseria mucosa in a patient with chronic granulomatous disease. (1985) (22)
Effects of cell concentration and various anticoagulants on neutrophil migration. (1973) (22)
Glandular secretion of lactoferrin in a patient with neutrophil lactoferrin deficiency. (1989) (22)
TNF overproduction impairs epithelial staphylococcal response in hyper IgE syndrome (2018) (22)
Studies in normal and chronic granulomatous disease neutrophils indicate a correlation of tubulin tyrosinolation with the cellular redox state. (1983) (21)
Absence of the Largest Platelet-von Willebrand Multimers in a Patient with Lactoferrin Deficiency and a Bleeding Tendency (1992) (19)
Managing the interface between medical schools, hospitals, and clinical research. (1997) (19)
Dynamics of human neutrophil receptors for the chemoattractant fmet-leu-phe. (1983) (18)
Serum Concentrations of Lipids in Rabbits Infected with Escherichia Coli and Staphylococcus aureus 1 (1970) (18)
NADPH Oxidase-2 and AtherothrombosisHighlights (2017) (18)
Stature and weight in chronic granulomatous disease. (1984) (17)
ALTERATION OF MACROPHAGE AND MONOCYTE MEMBRANE POTENTIAL BY CHEMOTACTIC FACTORS (1980) (17)
Interferon-gamma in the management of chronic granulomatous disease. (1991) (17)
Intravenous endotoxin recruits a distinct subset of human neutrophils, defined by monoclonal antibody 31D8, from bone marrow to the peripheral circulation. (1989) (16)
Effects of storage and radiation on human neutrophil function in vitro (1987) (15)
Evolution of the hyperimmunoglobulin E and recurrent infection (HIE, JOB's) syndrome in a young girl. (1987) (15)
Innate Immunity against Granulibacter bethesdensis, an Emerging Gram-Negative Bacterial Pathogen (2011) (15)
Neutrophil chemoattractant fMet-Leu-Phe receptor expression and ionic events following activation. (1984) (14)
The molecular biology of selected phagocyte defects. (1989) (14)
Principles and Practice of Clinical Research Ed. 3 (2012) (14)
Effect of Vitamin C on Tubulin Tyrosinolation in Polymorphonuclear Leukocytes (1987) (13)
Ionic requirements and subcellular localization of tubulin tyrosinolation in human polymorphonuclear leukocytes. (1986) (13)
Persistence of the Bacterial Pathogen Granulibacter bethesdensis in Chronic Granulomatous Disease Monocytes and Macrophages Lacking a Functional NADPH Oxidase (2013) (13)
Mediator release from basophil granulocytes in chronic myelogenous leukemia. (1976) (13)
Pretreatment of filtration leukapheresis donors with colchicine. (1978) (13)
A Brief Historical Perspective of Cancer Rehabilitation and Contributions From the National Institutes of Health (2017) (12)
Managing the Interface Between Medical Schools, Hospitals, and Clinical Research (1998) (12)
Granulocyte transfusion therapy in a child with chronic granulomatous disease and multiple red cell alloantibodies (1989) (12)
Neutrophil activation in systemic capillary leak syndrome (Clarkson disease) (2019) (12)
Minor errors in two published sequences. (1989) (12)
Hematologically important mutations: The autosomal forms of chronic granulomatous disease (third update). (2021) (11)
NCF1 (p47phox)-deficient chronic granulomatous disease: comprehensive genetic and flow cytometric analysis. (2019) (11)
Cloning and functional expression of the mouse homologue of p47phox (2004) (11)
Delineation of the phagocyte NADPH oxidase through studies of chronic granulomatous diseases of childhood. (1992) (11)
Interferon-γ in the treatment of the chronic granulomatous diseases of childhood (1991) (10)
Hematologically important mutations: X-linked chronic granulomatous disease (fourth update). (2021) (10)
The effect of hemodialysis and C5a des arg on neutrophil subpopulations. (1980) (10)
Chromobactehum violaceum Infectious and Chronic Granulomatous Disease (1983) (10)
Modulation of the inflammatory response by products released from human polymorphonuclear leukocytes during phagocytosis (1975) (9)
Unique human neutrophil populations are defined by monoclonal antibody ED12F8C10. (1991) (9)
Elevated urinary histamine in the hyperimmunoglobulin E and recurrent infection (Job's) syndrome: association with eczematoid dermatitis and not with infection. (1987) (9)
Human non-transformed monocyte-derived macrophage cell lines. (1989) (9)
Simultaneous Host-Pathogen Transcriptome Analysis during Granulibacter bethesdensis Infection of Neutrophils from Healthy Subjects and Patients with Chronic Granulomatous Disease (2015) (8)
Neutrophil activation studied using the two indirect probes of membrane potential which respond by different fluorescence mechanisms. (1982) (8)
Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas (2021) (8)
ROLE OF NEUTROPHIL LYSOSOMAL GRANULES IN THE EVOLUTION OF THE INFLAMMATORY RESPONSE (1982) (8)
Chemotactic disorders. (1988) (8)
Deficiency in C3b receptors on neutrophils of patients with chronic granulomatous disease and hyperimmunoglobulin-E recurrent infection (Job's) syndrome (1984) (8)
Anesthetic considerations in patients with chronic granulomatous disease. (1990) (8)
Abnormal rabbit heterophil chemotaxis following thermal injury. An in vivo model of an abnormality of the chemoattractant receptor for f-met-leu-phe. (1988) (8)
Neutrophils are hyperpolarized after exudation and show an increased depolarization response to formyl‐peptide but not to phorbol myristate acetate (1987) (7)
Recombinant human interferon-y reconstitutes defective phagocyte function in patients with chronic granulomatous disease of childhood ( neutrophils / monocytes / lymphokine / superoxide / bactericidal activity ) (7)
NCF1 (p47 phox ) – de ﬁ cient chronic granulomatous disease: comprehensive genetic and ﬂ ow cytometric analysis (2019) (7)
Serologic reactivity to the emerging pathogen Granulibacter bethesdensis. (2012) (7)
Revitalization of the Warren G. Magnuson Clinical Center at the National Institutes of Health (1998) (7)
Increased serum levels of squalene in patients with acute influenza. (1970) (7)
Identification of the antigen recognized by the monoclonal antibody 31D8. (1996) (7)
B-cell activating factor (BAFF) is elevated in chronic granulomatous disease. (2013) (7)
Chromobacterium violaceum infectious and chronic granulomatous disease. (1983) (7)
Modulation of PMN receptors for chemotactic peptides (1983) (6)
Lipoidal Components of Bacterial Lipopolysaccharides: Nature and Distribution of Fatty Acids in Aerobacter aerogenes (1968) (6)
Interferon-gamma in the treatment of the chronic granulomatous diseases of childhood. (1991) (6)
An antibody to a subpopulation of neutrophils demonstrates antigenic heterogeneity which correlates with response heterogeneity. (1984) (6)
Studies of phagocytosis in chronic granulomatous disease (1987) (6)
Staining of Eosinophils with Nitroblue Tetrazolium in Patients with Chronic Granulomatous Disease (1986) (6)
A Historical Perspective on Clinical Research (2012) (5)
Mobilization and adaptation of human neutrophil chemoattractant n formylmethionylleucylphenylalanine receptors (1984) (5)
Twenty-Year Follow-Up of Esophageal Involvement in Chronic Granulomatous Disease (2009) (5)
Thoracic Surgery in Chronic Granulomatous Disease: a 25-Year Single-Institution Experience (2016) (5)
Chapter 1 – A Historical Perspective on Clinical Research (2002) (4)
Advances in Immunology: Immunodeficiency Diseases Caused by Defects in Phagocytes (2000) (4)
Early Intracellular Trafficking of Granulibacter bethesdensis in Human Macrophages (2017) (4)
Chronic Granulomatous Disease: From Lethal Pediatric Mystery to Complex Chronic Disease (2010) (4)
IL-8 in Human Neutrophils -Dependent Production and Release of 2+ Ca (1998) (4)
The NIH Clinical Center and the future of clinical research (2011) (4)
Evaluation of the Patient with Suspected Immunodeficiency (2015) (4)
Radioassay of Granulocyte Chemotaxis (1974) (4)
New infrastructure to support clinical translational research at the US National Institutes of Health: role of the NIH Clinical Center (2012) (3)
A novel post-translational incorporation of tyrosine into multiple proteins in activated human neutrophils. Correlation with phagocytosis and activation of the NADPH oxidase-mediated respiratory burst. (1992) (3)
Granulibacter bethesdensis, a Pathogen from Patients with Chronic Granulomatous Disease, Produces a Penta-Acylated Hypostimulatory Glycero-D-talo-oct-2-ulosonic Acid–Lipid A Glycolipid (Ko-Lipid A) (2021) (2)
Response to: "Rescuing the NIH before it is too late". (2006) (2)
Reconstitution of defective phagocyte function in chronic granulomatous disease of childhood with recombinant human interferon-gamma. (1988) (2)
Dominantly transmitted hematologic dysfunction clinically similar to fanconi's anemia (1989) (2)
Immunologic Reactivity of the Lung (1977) (2)
A marker of neutrophil heterogeneity reveals two forms of chronic myelogenous leukemia. (1985) (2)
Neutrophil-speciﬁc Granule Deﬁciency Results from a Novel Mutation with Loss of Function of the Transcription Factor CCAAT/Enhancer Binding Protein (cid:101) (1999) (2)
Abnormal bone scintigraphy before clinical symptoms in a patient with defective phagocyte function. (1993) (2)
NIH Clinical Center (2020) (2)
Taming Clinical Research's Paper Tigers (2006) (2)
Radioassay of granulocyte chemotaxis. Studies of human granulocytes and chemotactic factors. (1974) (1)
2007 Association of American Physicians George M. Kober Medal: Introduction of Anthony S. Fauci, MD (2007) (1)
172 Comparatively Diminished Cytokine and Superoxide Induction by the Emerging Pathogen Granulibacter bethesdensis: Implications for Pathogenesis (2007) (1)
Nine patients with chronic granulomatous disease having selective neck dissection for severe cervical lymphadenitis (2018) (1)
Modulation of tubulin tyrosinolation in human polymorphonuclear leukocytes (PMM). (1984) (1)
A simple micromethod for leukocyte rosetting without cell purification. (1983) (1)
Separation and function of neutrophil karyogranuloplasts and comparison with cytoplasts and intact cells (1987) (1)
The p 47 p ~ x Mouse Knock-Out Model o f Chronic Granulomatous Disease (2003) (1)
New infrastructure to support clinical translational research at the US National Institutes of Health: role of the NIH Clinical Center (2012) (1)
Editorial: CD8 T cells cut back on calcium intake in the lungs (2010) (1)
Endoscopic Features of Gastrointestinal Disease in Chronic Granulomatous Disease: A Distinct Entity: 1267 (2011) (1)
Low Plasma Gelsolin Concentrations in Chronic Granulomatous Disease (2020) (1)
Pus potassium (2004) (1)
The need for clinical research education in the medical school curriculum. (1998) (1)
Reversion mutations in patients with leukocyte adhesion deficiency type I leading to CD18 expression on CD3+/CD8+/CD57+ T cells (2002) (1)
Serum squalene and methyl sterols. (1970) (1)
Introduction of Anthony S. Fauci, MD: 2007 Association of American Physicians George M. Kober Medal. (2007) (1)
John I. Gallin, MD, Director, NIH Clinical Center (2007) (1)
IRAK-4: A key kinase involved in toll-like receptor signaling and resistance to bacterial infection (2006) (1)
Interferon- and Management of Infectious Diseases (1996) (0)
Binding of immunoglobulin- and complement-coated erythrocytes to human neutrophil subpopulations (1981) (0)
Neutrophil Chemotaxis (1980) (0)
Leukocyte chemotaxis. (1983) (0)
The Gastrointestinal Manifestations of Chronic Granulomatous Disease: 1268 (2011) (0)
Leukotriene B Formyl-Methionyl-Leucyl-Phenylalanine or Neutrophils Stimulated with Fibrinogen Induces IL-8 Synthesis in Human and (2001) (0)
Formyl-Methionyl-Leucyl-Phenylalanine or Neutrophils Stimulated with Fibrinogen Induces IL-8 Synthesis in Human (2013) (0)
Human nontransformed monocyte macrophage cell lines (1987) (0)
A Platform Minigene AAVS1 Targeted Safe Harbor Approach For Genetic Correction Of iPSC Derived From Patients With Each Of The 5 Genetic Forms Of Chronic Granulomatous Disease (2013) (0)
Electrophysiology of human macrophage stimulation by endotoxin activated serum (1976) (0)
Immune therapy and potential for gene therapy in chronic granulomatous disease of childhood (1992) (0)
Novel post-translational incorporation of tyrosine in PMA-activated polymorphonuclear leukocytes (PMN) (1986) (0)
progression myelogenous leukemia and its absence may be a marker of disease A neutrophil membrane marker reveals two groups of chronic (2011) (0)
Herniated Nuclear Morphology and Cytoskeletal Anomalies in Neutrophils from Sisters with Recurrent Infections (2008) (0)
Components of the IL-1 Receptor Complex Alters Normal IRAK-4 Interaction with Patient with Recurrent Bacterial Infections Proteins with Mutations Identified in a Receptor-Associated Kinase-4 (IRAK-4) Cutting Edge: Expression of IL-1 (2005) (0)
Acquired immunodeficiency syndrome (AIDS). (1985) (0)
Modulation of the Chemoattractant Receptor for fmet-leu-phe during Neutrophil Activation, Adaptaion and Deactivation* (1983) (0)
Phagocyte Function and Dysfunction: From Descriptive Biology to Molecular Defects and Cytokine Therapy (2001) (0)
S 6 Infections in Patients with Innate Immunity , Primary Immunodeficiency and Neonates (2008) (0)
Effects of Levamisole on Normal and Abnormal (1977) (0)
Gastrointestinal Computed Tomography Findings in Chronic Granulomatous Disease with Subgroup Clinicopathologic Analysis (2021) (0)
Low Plasma Gelsolin Concentrations in Chronic Granulomatous Disease (2020) (0)
Thoracic Surgery in Chronic Granulomatous Disease: a 25-Year Single-Institution Experience (2016) (0)
Antifungal activities of natural and synthetic iron chelators alone and in 1 (2009) (0)
Impaired Priming and Activation of the NADPH Oxidase in Patients with TLR Signaling Defects (2008) (0)
Endotoxin and lipids. (1972) (0)
Su1353 Longstanding Chronic Granulomatous Disease Colitis Does Not Increase the Risk of Colorectal Cancer (2014) (0)
Book ReviewChemotaxis and Inflammation. (1974) (0)
Assessment of Atherosclerosis in Chronic Granulomatous Disease Running title: Sibley et al.; Atherosclerosis in CGD (2014) (0)
The Use of Radiolabelled 18-F-2-Deoxy-2-Fluro-Glucose (18-FDG) in Combined Positron Emission Tomography-Computed Tomography (PET-CT) to Evaluate Infection: Lessons Learned from a Case Series of 23 Patients with Chronic Granulomatous Disease (CGD) (2015) (0)
Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury (2023) (0)
PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS Cytoskeletal abnormalities and neutrophil dysfunction in WDR 1 de fi ciency (2016) (0)
Gastrointestinal and Hepatic Manifestations of Chronic Granulomatous Disease. (2023) (0)
Chromium-51 radioimmunoassay for chemotaxis. (1988) (0)
The dysmorphology and genetics of job hyper IgE syndrome. (1997) (0)
The Effect of Hemodialysis and C5adesarg #{176}n Neutrophil Subpopulations (1980) (0)
Su1927 GASTROINTESTINAL IMAGING IN CHRONIC GRANULOMATOUS DISEASE: CT FINDINGS IN 141 PATIENTS WITH CLINICOPATHOLOGIC CORRELATION (2020) (0)
Michael M. Frank: February 28, 1937–August 1, 2019 (2019) (0)
Superoxide-independent kynurenine synthesis in human chronic granulomatous disease: A ‘radical’ difference between mice and humans (2009) (0)
EVALUATION OF THE PATIENT WITH RECURRENT BACTERIAL (1998) (0)
Disease Dysregulation in Chronic Granulomatous Production by Hydrogen Peroxide and Inhibition of Human Neutrophil IL-8 Alvord and (2004) (0)
OxidaseMacrophages Lacking a Functional NADPH Granulomatous Disease Monocytes and in Chronic Granulibacter bethesdensis Persistence of the Bacterial Pathogen (2013) (0)
Neutrophils Collected by Continuous Flow Filtration Leukopheresis (2017) (0)
[5] Chromium-51 radioimmunoassay for chemotaxis (1988) (0)
May 8, 1984, NIH Record, Vol. XXXVI, No. 10 (2019) (0)
INTEFERON-GAMMA AND MANAGEMENT OF INFECTIOUS DISEASES. AUTHORS' REPLY (1996) (0)
Contributors (2015) (0)

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