John H. Newman

John H. Newman's AcademicInfluence.com Rankings

John H. Newman

Philosophy

#11201

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#15393

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#8007

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#9967

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Philosophy

John H. Newman's Degrees

Doctorate Medicine Harvard University

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John H. Newman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. (1992) (1232)
Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology. (2013) (750)
Inflammation, growth factors, and pulmonary vascular remodeling. (2009) (663)
Genetics and genomics of pulmonary arterial hypertension. (2009) (641)
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. (2001) (552)
Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred. (2001) (364)
Localization of the gene for familial primary pulmonary hypertension to chromosome 2q31–32 (1997) (279)
Genetic anticipation and abnormal gender ratio at birth in familial primary pulmonary hypertension. (1995) (254)
Genetic basis of pulmonary arterial hypertension: current understanding and future directions. (2004) (241)
Respiratory failure after endotoxin infusion in sheep: lung mechanics and lung fluid balance. (1982) (194)
Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects (2015) (187)
Longitudinal analysis casts doubt on the presence of genetic anticipation in heritable pulmonary arterial hypertension. (2012) (170)
A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension (2018) (169)
Association of the metabolic syndrome with pulmonary venous hypertension. (2009) (168)
Pulmonary veno-occlusive disease caused by an inherited mutation in bone morphogenetic protein receptor II. (2003) (152)
High Prevalence of Occult Pulmonary Venous Hypertension Revealed by Fluid Challenge in Pulmonary Hypertension (2014) (152)
Pulmonary artery adventitial changes and venous involvement in primary pulmonary hypertension. (1995) (149)
Clinical and Biological Insights Into Combined Post- and Pre-Capillary Pulmonary Hypertension. (2016) (142)
Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension (2016) (140)
Unrecognized glucose intolerance is common in pulmonary arterial hypertension. (2010) (138)
Airway and vascular effects of 8-epi-prostaglandin F2 alpha in isolated perfused rat lung. (1993) (135)
Gene expression in BMPR2 mutation carriers with and without evidence of Pulmonary Arterial Hypertension suggests pathways relevant to disease penetrance (2008) (133)
Familial primary pulmonary hypertension: clinical patterns. (1984) (126)
Effects of a novel prostaglandin, 8-epi-PGF2 alpha, in rabbit lung in situ. (1992) (125)
Genetics and genomics of pulmonary arterial hypertension. (2013) (124)
Penetrance of pulmonary arterial hypertension is modulated by the expression of normal BMPR2 allele (2009) (122)
Physician practices in the treatment of pulmonary embolism and deep venous thrombosis. (1988) (121)
Truncating and missense BMPR2 mutations differentially affect the severity of heritable pulmonary arterial hypertension (2009) (107)
Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. (2004) (105)
Heterogeneity of pathologic lesions in familial primary pulmonary hypertension. (1988) (103)
Narrative Review: The Enigma of Pulmonary Arterial Hypertension: New Insights from Genetic Studies (2008) (93)
Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension. (2006) (93)
A survey of diagnostic practices and the use of epoprostenol in patients with primary pulmonary hypertension. (1998) (89)
PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics. (2017) (84)
High-altitude disorders: pulmonary hypertension: pulmonary vascular disease: the global perspective. (2010) (80)
Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension (2015) (75)
Effects of 100% oxygen on lung vascular function in awake sheep. (1983) (75)
Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle. (2016) (72)
Peripheral Blood Signature of Vasodilator-Responsive Pulmonary Arterial Hypertension (2015) (71)
An official American Thoracic Society Statement: pulmonary hypertension phenotypes. (2014) (68)
Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension. (2016) (68)
Changes in pulmonary vascular tone during exercise. Effects of nitric oxide (NO) synthase inhibition, L-arginine infusion, and NO inhalation. (1994) (65)
Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. (2010) (65)
Physical activity limitation as measured by accelerometry in pulmonary arterial hypertension. (2012) (65)
Testosterone negatively regulates right ventricular load stress responses in mice (2012) (61)
Enhancing Insights into Pulmonary Vascular Disease through a Precision Medicine Approach. A Joint NHLBI-Cardiovascular Medical Research and Education Fund Workshop Report. (2017) (60)
Synergistic heterozygosity for TGFβ1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension (2008) (59)
Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder (2018) (51)
Causes of pulmonary hypertension in the elderly. (2014) (50)
Bedside end-tidal CO2 tension as a screening tool to exclude pulmonary embolism (2009) (49)
High-altitude pulmonary hypertension in cattle (brisket disease): Candidate genes and gene expression profiling of peripheral blood mononuclear cells (2011) (48)
Adenosine Produces Pulmonary Vasoconstriction in Sheep: Evidence for Thromboxane A2/Prostaglandin Endoperoxide- Receptor Activation (1989) (47)
Human PAH is characterized by a pattern of lipid-related insulin resistance. (2019) (45)
Lung vascular effects of phorbol myristate acetate in awake sheep. (1983) (45)
A window into living with an undiagnosed disease: illness narratives from the Undiagnosed Diseases Network (2017) (44)
Exercise-induced pulmonary vasoconstriction during combined blockade of nitric oxide synthase and beta adrenergic receptors. (1994) (42)
Venous and arterial changes in pulmonary veno-occlusive disease, mitral stenosis and fibrosing mediastinitis. (2000) (42)
Hemodynamic Evidence of Vascular Remodeling in Combined Post- and Precapillary Pulmonary Hypertension (2016) (39)
Use of Pulmonary Arterial Hypertension–Approved Therapy in the Treatment of Non–Group 1 Pulmonary Hypertension at US Referral Centers (2015) (39)
Reversal of hypereosinophilic syndrome and lymphomatoid papulosis with mepolizumab and imatinib. (2003) (37)
Doppler estimation of changes in pulmonary artery pressure during hypoxic breathing. (1991) (35)
Septicemia and lung injury. (1983) (33)
Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling (2020) (33)
Hemodynamic Improvement of Pulmonary Arterial Hypertension After Bariatric Surgery: Potential Role for Metabolic Regulation (2013) (33)
Effect of progressive exercise on lung fluid balance in sheep. (1988) (32)
Limitations of exome sequencing in detecting rare and undiagnosed diseases (2020) (32)
Prostanoids but not oral therapies improve right ventricular function in pulmonary arterial hypertension. (2013) (32)
Relation of blood-free to blood-inclusive postmortem lung water measurements in sheep. (1985) (31)
Venous and arterial changes in pulmonary veno-occlusive disease, mitral stenosis and fibrosing mediastinitis (2000) (31)
The presence of genetic anticipation suggests that the molecular basis of familial primary pulmonary hypertension may be trinucleotide repeat expansion. (1997) (31)
Idiopathic and heritable PAH perturb common molecular pathways, correlated with increased MSX1 expression (2011) (30)
Shorter Survival in Familial versus Idiopathic Pulmonary Arterial Hypertension is Associated with Hemodynamic Markers of Impaired Right Ventricular Function (2013) (29)
Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision (2021) (29)
Pressure and flow changes in the pulmonary circulation in exercising sheep: evidence for elevated microvascular pressure. (1993) (29)
Treatment of primary pulmonary hypertension -- the next generation. (2002) (28)
Mechanistic Phase II Clinical Trial of Metformin in Pulmonary Arterial Hypertension (2020) (28)
Right Heart Adaptation to Pulmonary ArterialHypertension (2013) (27)
Exercise training in pulmonary hypertension: implications for the evaluation of drug trials. (2006) (24)
Six-minute walk distance in healthy young adults. (2020) (24)
Inhaled nitric oxide reduces lung fluid filtration after endotoxin in awake sheep. (1998) (23)
Clearance of filtered fluid from the lung during exercise: role of hyperpnea. (2001) (22)
Primary pulmonary hypertension: a look at the future. (1989) (22)
Lung mechanics and airway reactivity in sheep during development of oxygen toxicity. (1990) (21)
Blunted pulmonary pressor responses to hypoxia in blood perfused, ventilated lungs isolated from oxygen toxic rats: possible role of prostaglandins. (1981) (21)
Effect of acute arteriolar vasodilation on capacitance and resistance in pulmonary arterial hypertension. (2015) (21)
Adrenergic modulation of the pulmonary circulation during strenuous exercise in sheep. (1993) (20)
Lungs at high-altitude: genomic insights into hypoxic responses. (2015) (20)
Characteristics of undiagnosed diseases network applicants: implications for referring providers (2018) (19)
Pulmonary vascular effect of insulin in a rodent model of pulmonary arterial hypertension (2017) (18)
Thromboxane A2 and prostacyclin do not modulate pulmonary hemodynamics during exercise in sheep. (1986) (17)
Cyclooxygenase inhibition during phorbol-induced granulocyte stimulation in awake sheep. (1984) (17)
[Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology]. (2014) (17)
Pulmonary vascular effects of prostaglandin D2, but not its systemic vascular or airway effects, are mediated through thromboxane receptor activation. (1991) (16)
Genetics of primary pulmonary hypertension. (2001) (16)
End tidal CO(2) tension: pulmonary arterial hypertension vs pulmonary venous hypertension and response to treatment. (2011) (15)
Whole genome sequencing reveals novel IGHMBP2 variant leading to unique cryptic splice‐site and Charcot‐Marie‐Tooth phenotype with early onset symptoms (2019) (15)
Treatment of Primary Pulmonary Hypertension — The Next Generation (2002) (15)
Pulmonary vasoconstriction induced by mitral valve obstruction in sheep. (1998) (15)
Human recombinant interleukin 2-activated sheep lymphocytes lyse sheep pulmonary microvascular endothelial cells. (1989) (14)
Evaluation of Tp-e interval and Tp-e/QT ratio in patients with rheumatoid arthritis. (2014) (14)
Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep. (1986) (14)
Evidence for inflammatory signaling in idiopathic pulmonary artery hypertension: TRPC6 and nuclear factor-kappaB. (2009) (14)
The Diastolic Pressure Gradient Does Not-and Should Not-Predict Outcomes. (2015) (14)
Ambrisentan (2020) (13)
BMPR2 dysfunction impairs insulin signaling and glucose homeostasis in cardiomyocytes. (2019) (12)
Phenotypic heterogeneity of ZMPSTE24 deficiency (2018) (12)
Differing effects of nitrogen mustard and hydroxyurea on lung O2 toxicity in adult sheep. (1992) (12)
Effects of methylprednisolone on lung oxygen toxicity in awake sheep. (1986) (12)
New risks for pulmonary hypertension: need for a large epidemiologic study. (2006) (11)
Hypertensive pulmonary vascular disease: dawn of the age of prevention? (2000) (11)
Lung vascular injury. (1988) (11)
Identifying digenic disease genes using machine learning in the undiagnosed diseases network (2020) (10)
Pulmonary Hypertension by the Method of Paul Wood. (2020) (10)
Metabolites of arachidonic acid in the pathophysiology of the pulmonary circulation. (1982) (10)
Biallelic MADD variants cause a phenotypic spectrum ranging from developmental delay to a multisystem disorder. (2020) (9)
Granulocytes in Acute Lung Vascular Injury in Unanesthetized Sheep (1982) (9)
PGF2α Causes Bronchoconstriction and Pulmonary Vasoconstriction Via Thromboxane Receptors in Rat Lung (1996) (9)
Distribution of mast cells and histamine in canine pulmonary arteries. (1980) (8)
Postdeployment Respiratory Syndrome in Soldiers With Chronic Exertional Dyspnea (2021) (8)
Variants in PRKAR1B cause a neurodevelopmental disorder with autism spectrum disorder, apraxia, and insensitivity to pain (2020) (7)
Echocardiographic Detection of Occult Diastolic Dysfunction in Pulmonary Hypertension After Fluid Challenge (2019) (7)
Nitric oxide and nitroglycerin reversal of pulmonary vasoconstriction induced by alpha-activation during exercise. (1996) (7)
Rare Variants in the Gene ALPL That Cause Hypophosphatasia Are Strongly Associated With Ovarian and Uterine Disorders (2018) (7)
Simultaneous exposure of sheep to endotoxin and 100% oxygen. (1991) (7)
Effects of alveolar hypoxia during partial mitral valve obstruction in unanesthetized sheep. (1985) (7)
Postnatal changes in response of canine neonatal pulmonary arteries to histamine. (1979) (7)
Vascular homeostasis at high-altitude: role of genetic variants and transcription factors (2020) (6)
Variability in Hemodynamic Evaluation of Pulmonary Hypertension at Large Referral Centers (2014) (6)
IgG4‐related disease: Association with a rare gene variant expressed in cytotoxic T cells (2019) (6)
Acute effects of atrial natriuretic peptide on lung mechanics and hemodynamics in awake sheep. (1990) (6)
Familial Autonomic Ganglionopathy Caused by Rare CHRNA3 Genetic Variants (2021) (5)
Magnetic Resonance Imaging characteristics in case of TOR1AIP1 muscular dystrophy. (2019) (5)
Effects of endotoxin on human pulmonary circulation (1994) (5)
Clinical Characteristics and Transplant-Free Survival Across the Spectrum of Pulmonary Vascular Disease. (2022) (5)
Genetic Basis of Pulmonary Hypertension (1986) (5)
Phenotypic Profiling in Subjects Heterozygous for 1 of 2 Rare Variants in the Hypophosphatasia Gene (ALPL) (2020) (4)
One is the loneliest number: genotypic matchmaking using the electronic health record (2021) (4)
Alcohol intolerance associated with Hodgkin lymphoma (2013) (4)
End‐Tidal Carbon Dioxide as a Prognostic Feature in Pulmonary Arterial Hypertension (2017) (4)
Molecular Rescue in Pulmonary Arterial Hypertension. (2021) (3)
Pulmonary hypertension. (2005) (3)
Genes and Pulmonary Hypertension: Update 2006 (2006) (3)
Clinical trials in pulmonary hypertension: Time for a consortium (2013) (3)
Inﬂammation, Growth Factors, and Pulmonary Vascular Remodeling (2016) (3)
Pulmonary Arterial Hypertension vs Pulmonary Venous Hypertension and Response to Treatment (2015) (3)
Characterization of Immunopathology and Small Airway Remodeling in Constrictive Bronchiolitis. (2022) (3)
Erratum: De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia (The American Journal of Human Genetics (2019) 105(2) (413–424), (S0002929719302393), (10.1016/j.ajhg.2019.06.014)) (2019) (3)
P-31 magnetic resonance spectroscopy and near-infrared spectroscopy provide unique quantitative data for evaluation of exercising muscles (1994) (2)
Design and Effectiveness of an Animated Module that Integrates Basic and Clinical Pulmonary Mechanics for Medical Students (2015) (2)
Factors influencing lung histamine content (1981) (2)
0169 Pulmonary arterial pressure in yearling Angus cattle managed at high altitude: Study of a non-synonymous SNP in the oxygen-dependent degradation domain of the endothelial PAS domain-containing protein 1 gene. (2016) (2)
Predictors of Diastolic-To-Wedge Gradient in Patients Evaluated for Pulmonary Hypertension (2013) (2)
Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases (2021) (2)
Genomics of Pulmonary Arterial Hypertension (2013) (2)
Airway responsiveness in isolated perfused rat lungs: effect of thoracic irradiation. (1989) (2)
Bedside end tidal CO2 as a screening tool to exclude pulmonary embolism (2009) (2)
Clinical Trial of Metformin in Pulmonary Arterial Hypertension (2019) (1)
Giants in chest medicine: Richard W. Light, MD. (2014) (1)
INCREASED-PERMEABILITY PULMONARY EDEMA FROM SEPSIS/ENDOTOXEMIA (1998) (1)
Abstract 18041: Dysregulated Fatty Acid Metabolism in Pulmonary Arterial Hypertension is Associated with Right Ventricular Steatosis and Lipotoxicity (2014) (1)
Mutant BMPR2 expression in cardiomyocytes results in an altered hypertrophic response (1090.2) (2014) (1)
176 Genotyping a SNP in the endothelial PAS domain-containing protein 1 (EPAS1) gene: is it associated with mean pulmonary arterial pressures in yearling Angus cattle? (2017) (1)
Fluid Challenge To Identify Pulmonary Venous Hypertension (2013) (1)
Changes in Pulmonary Vascular Tone during Exercise (1)
INHIBITION OF ENDOGENOUS NITRIC OXIDE DURING ENDOTOXEMIA IN AWAKE SHEEP - EFFECTS OF N ω -NITRO-L-ARGININE ON THE DISTRIBUTION OF PULMONARY VASCULAR RESISTANCE AND PROSTANOID PRODUCTS (2002) (1)
The First Annual Drug Discovery and Development Symposium for Pulmonary Hypertension (2014) (1)
The Light at the End of the Long Pulmonary Hypertension Tunnel Brightens. (2018) (1)
The Role of Aldosterone in Pulmonary Venous Hypertension: Response (2010) (0)
Effects Of Estrogen Deprivation In The Unstressed And Stressed Right Ventricle (2011) (0)
[Genetics and genomics of pulmonary arterial hypertension]. (2014) (0)
Functional Assessment in Pulmonary Arterial Hypertension Measured by Spontaneous Daily Walking. (2009) (0)
A Case Study of Dysfunctional Nicotinamide Metabolism in a 20-Year-Old Male (2023) (0)
612 Treatment of Non-Group 1 Pulmonary Hypertension: Results of a Survey of Pulmonary Hypertension Centers in the United States (2012) (0)
Abstract 16661: Fluid Challenge During Right Heart Catheterization for Evaluation of Pulmonary Hypertension Identifies Patients With Decreased Right Ventricular Function (2020) (0)
Genomic Biomarkers And Cellular Pathways Of High Altitude Pulmonary Hypertension In Cattle By RNA Gene Expression Profiling (2011) (0)
The Combination of Normal Bedside End Tidal CO2 and Low Wells Score Accurately Excludes Pulmonary Embolism. (2009) (0)
Choice Of Therapy In Pulmonary Arterial Hypertension: Results Of A Survey Of Practice Patterns In The Treatment Of Pulmonary Arterial Hypertension (2012) (0)
Importance of Early Diagnosis (2012) (0)
Urinary Estrogen Metabolites May Predict Familial Pulmonary Arterial Hypertension Status in Females. (2009) (0)
Family History, Gender and theBMPR2Mutation Type Influence Clinical Outcomes in Pulmonary Arterial Hypertension (PAH). (2009) (0)
A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative (2018) (0)
Heritable and Idiopathic Forms of Pulmonary Arterial Hypertension (2020) (0)
Abstract P176: Familial Autonomic Ganglionopathy Caused by Rare CHRNA3 Genetic Variants. Novel Genetic Cause of Neurogenic Orthostatic Hypotension (2019) (0)
Abstract 16026: Genetic Variation of Oxidative Phosphorylation Genes Associate With Right Ventricular Function in Patients With Pulmonary Arterial Hypertension (2017) (0)
VarSight: prioritizing clinically reported variants with binary classification algorithms (2019) (0)
Age Is Not Associated with Six-Minute Walk Distance in Healthy Adults Aged 18 - 50 (2019) (0)
The Future of Genetics in Pulmonary Arterial Hypertension (2005) (0)
Accelerometry As A Novel Method Of Functional Assessment In Pulmonary Arterial Hypertension (2011) (0)
ARDS: New insights and unsolved problems (2005) (0)
End Tidal Carbon Dioxide: Pulmonary Arterial Hypertension Versus Pulmonary Venous Hypertension And Response To Treatment (2011) (0)
Comprehensive Analysis of Lung Pathology in Soldiers Diagnosed with Constrictive Bronchiolitis (2020) (0)
ON THE KINSHIP OF SPIRIT AND THOUGHT (2022) (0)
Testosterone Is Important In Right Ventricular Function At Baseline And In Load Stress (2010) (0)
The Global Perspective Hypertension : Pulmonary Vascular Disease: High-Altitude Disorders: Pulmonary (2010) (0)
Recent trends in venous thrombosis and pulmonary embolism. (1997) (0)
Differences in Average Age of Onset, Locus Heterogeneity, and Penetrance between Familial Pulmonary Arterial Hypertension and Familial Interstitial Pneumonia Can Predict the Success of Linkage and Whole Exome Sequencing in Discovering Disease-Causing Alleles (2012) (0)
Message from the Board Chair (2006) (0)
SUN-528 The Clinical Utility of Gene Sequencing in Hypophosphatasia: Lessons from Patients with Two Rare Variants (2019) (0)
Chasing Pulmonary Hypertension: 1980–2012 (2012) (0)
RESTING ECHOCARDIOGRAPHIC DIASTOLIC MEASURES FAIL TO PREDICT OCCULT DIASTOLIC DYSFUNCTION AFTER RIGHT HEART CATHETERIZATION WITH FLUID CHALLENGE (2018) (0)

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What Schools Are Affiliated With John H. Newman?

John H. Newman is affiliated with the following schools:

Paris-Saclay University
Meharry Medical College
Vanderbilt University
Massachusetts General Hospital
Harvard University