John Hall Richards | Academic Influence

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John Hall Richards's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Determination of intracellular pH by 31P magnetic resonance. (1973) (1084)
The structure and action of proteins (1969) (489)
A chemically synthesized pre‐sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers. (1986) (363)
Tryptophan-Accelerated Electron Flow Through Proteins (2008) (348)
Amphiphilicity is essential for mitochondrial presequence function. (1988) (236)
Chemical Shifts in C_5H_5^-, C_6H_6 and C_7H_7^+; Chemical Shifts and π-Electron Densities (1960) (221)
Electron Tunneling in Proteins: Coupling Through a β Strand (1995) (202)
Carbon nuclear magnetic resonance studies of the histidine residue in alpha-lytic protease. Implications for the catalytic mechanism of serine proteases. (1973) (198)
Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function. (1982) (154)
PROTONATION OF METALLOCENES BY STRONG ACIDS. STRUCTURE OF THE CATION (1960) (115)
Carbonium Ion Stabilization by Metallocene Nuclei. II. α-Metallocenylcarbonium Ions (1961) (113)
α-metallocenyl carbonium ions (1959) (107)
The biosynthesis of steroids, terpenes, and acetogenins (1964) (105)
Construction and characterization of an azurin analog for the purple copper site in cytochrome c oxidase. (1996) (104)
Carbonium Ion Stabilization by Metallocene Nuclei. III. Evidence for Metal Participation (1961) (103)
Mimicking protein-protein electron transfer: voltammetry of Pseudomonas aeruginosa azurin and the Thermus thermophilus Cu(A) domain at omega-derivatized self-assembled-monolayer gold electrodes. (2004) (93)
Water-soluble, recombinant CuA-domain of the cytochrome ba3 subunit II from Thermus thermophilus. (1996) (90)
Electron tunneling in biological molecules (1999) (86)
Coupling to Lysine-13 Promotes Electron Tunneling through Carboxylate-Terminated Alkanethiol Self-Assembled Monolayers to Cytochrome c (2003) (84)
Mechanism of action of adenosylcobalamin: glycerol and other substrate analogues as substrates and inactivators for propanediol dehydratase--kinetics, stereospecificity, and mechanism. (1977) (82)
Properties of photogenerated tryptophan and tyrosyl radicals in structurally characterized proteins containing rhenium(I) tricarbonyl diimines. (2001) (81)
Type Zero Copper Proteins (2009) (81)
The crystal structure of α‐keto‐1,1'‐trimethyleneferrocene (1965) (75)
Mechanism of action of serine proteases: tetrahedral intermediate and concerted proton transfer. (1976) (74)
Inner- and outer-sphere metal coordination in blue copper proteins. (2012) (66)
The structure and bonding of ferrocenylcarbonium ions (1973) (64)
Structurally engineered cytochromes with unusual ligand-binding properties: expression of Saccharomyces cerevisiae Met-80-->Ala iso-1-cytochrome c. (1993) (64)
An outer-sphere hydrogen-bond network constrains copper coordination in blue proteins. (2002) (63)
Long-Range Electron Transfer in Ruthenium-Modified Cytochromes c. σ-Tunneling Pathways through Aromatic Residues (1993) (58)
Site-saturation studies of beta-lactamase: production and characterization of mutant beta-lactamases with all possible amino acid substitutions at residue 71. (1986) (58)
Blue to type 2 binding. Copper(II) and cobalt(II) derivatives of a Cys112Asp mutant of Pseudomonas aeruginosa azurin (1992) (55)
Gene synthesis, expression, and mutagenesis of the blue copper proteins azurin and plastocyanin. (1991) (54)
Excited-state dynamics of structurally characterized [ReI(CO)3(phen)(HisX)]+ (X = 83, 109) Pseudomonas aeruginosa azurins in aqueous solution. (2006) (52)
Immunoglobulins with hapten‐binding activity: structure‐function correlations and genetic implications (1978) (49)
13)C magnetic resonance studies of the binding of carbon monoxide to various hemoglobins (1974) (48)
Electron transfer reactivity of type zero Pseudomonas aeruginosa azurin. (2011) (45)
The Cu_A Center of a Soluble Domain from Thermus Cytochrome ba_3. An NMR Investigation of the Paramagnetic Protein (1996) (45)
Stability of wild‐type and mutant RTEM‐1 β‐lactamases: Effect of the disulfide bond (1987) (45)
Mechamism of action of coenzyme B12. Hydrogen transfer in the isomerization of methylmalonyl coenzyme A to succinyl coenzyme A. (1969) (45)
Substrate specificities in class A β‐lactamases: Preference for penams vs. cephams. The role of residues 237 (1989) (42)
Enzyme--substrate interaction by nuclear magnetic resonance. (1967) (42)
The Mechanism of the Photoconversion of Santonin (1963) (40)
Nuclear magnetic resonance studies of ^(13)CO monoxide binding to various hemoglobins (1972) (40)
Active-site mutants of beta-lactamase: use of an inactive double mutant to study requirements for catalysis. (1986) (40)
Long-range electron transfer in structurally engineered pentaammineruthenium (histidine-62) cytochrome c (1989) (39)
Electron transfer in ruthenium/zinc porphyrin derivatives of recombinant human myoglobins. Analysis of tunneling pathways in myoglobin and cytochrome c (1993) (39)
Batch Variation of Magnesium Stearate and its Effect on the Dissolution Rate of Salicylic Acid from Solid Dosage Forms (1982) (37)
Catalytic mechanism of serine proteases: reexamination of the pH dependence of the histidyl 1J13C2-H coupling constant in the catalytic triad of alpha-lytic protease. (1981) (37)
Outer-sphere contributions to the electronic structure of type zero copper proteins. (2012) (37)
Magnetic resonance studies of the binding of 13C-labeled carbon monoxide to myoglobins and hemoglobins containing modified hemes. (1977) (35)
Reaction of nickelocene with diazoalkanes (1968) (34)
An Analysis of the Nuclear Magnetic Resonance Spectra of Substituted Ferrocenes (1964) (33)
Electrochemistry of the CuA domain of Thermus thermophilus cytochrome ba3 (1996) (33)
Outer-sphere effects on reduction potentials of copper sites in proteins: the curious case of high potential type 2 C112D/M121E Pseudomonas aeruginosa azurin. (2010) (33)
Kinetic and thermodynamic consequences of the removal of the Cys-77-Cys-123 disulphide bond for the folding of TEM-1 beta-lactamase. (1997) (32)
Molecular studies of subspecificity differences among phosphorylcholine-binding mouse myeloma antibodies using 31P nuclear magnetic resonance. (1978) (31)
High-potential C112D/M121X (X = M, E, H, L) Pseudomonas aeruginosa azurins. (2009) (31)
Magnetic resonance studies of protein-small molecule interactions. Binding of N-trifluoroacetyl-D-(and L-)-p-fluorophenylalanine to -chymotrypsin. (1972) (30)
The Acetylation of Some Substituted Ferrocenes (1963) (29)
Magnetic resonance studies of the binding site interactions between phosphorylcholine and specific mouse myeloma immunoglobulin. (1977) (29)
X-ray Absorption Spectra of the Oxidized and Reduced Forms of C112D Azurin from Pseudomonas aeruginosa. (1999) (28)
Ionization behavior of the histidine residue in the catalytic triad of serine proteases. Mechanistic implications. (1973) (28)
Paramagnetic NMR spectroscopy and coordination structure of cobalt(II) Cys112Asp azurin (1995) (28)
Pulsed EPR/ENDOR characterization of perturbations of the Cu(A) center ground state by axial methionine ligand mutations. (2001) (27)
Electron Tunneling through Pseudomonas aeruginosa Azurins on SAM Gold Electrodes. (2008) (26)
METALLOCENYL CARBONIUM IONS. PARTICIPATION BY FERROCENE IN THE SOLVOLYSIS OF $beta$-FERROCENYLALKYL TOSYLATES. (1969) (25)
Site saturation of the histidine-46 position in Pseudomonas aeruginosa azurin: characterization of the His46Asp copper and cobalt proteins. (1993) (25)
Mechanism of serine protease action. Ionization behavior of tetrahedral adduct between α‐lytic protease and tripeptide aldehyde studied by carbon‐13 magnetic resonance (1975) (24)
The Role of Polymer Permeability in the Control of Drug Release (1985) (24)
Mechanism of action of adenosylcobalamin: hydrogen transfer in the inactivation of diol dehydratase by glycerol. (1978) (24)
Role of the active-site cysteine of Pseudomonas aeruginosa azurin. Crystal structure analysis of the CuII(Cys112Asp) protein (1997) (24)
Paramagnetic NMR Spectroscopy of Cobalt(II) and Copper(II) Derivatives of Pseudomonas aeruginosa His46Asp Azurin. (1997) (23)
Electron tunneling in proteins: coupling through a beta strand. (1995) (23)
Altering enzymatic activity: recruitment of carboxypeptidase activity into an RTEM beta-lactamase/penicillin-binding protein 5 chimera. (1990) (23)
Regulation of human neutrophil guanylate cyclase by metal ions, free radicals and the muscarinic cholinergic receptor. (1985) (22)
Probing folded and unfolded states of outer membrane protein a with steady-state and time-resolved tryptophan fluorescence. (2006) (21)
Notes on Molecular Orbital Calculations (1962) (21)
Structure-function relations in phosphorylcholine-binding mouse myeloma proteins. (1977) (21)
Spectroscopic studies of the nature of ligand bonding in carbonmonoxyhemoglobins: evidence of a specific function for histidine-E7 from infrared and nuclear magnetic resonance intensities. (1978) (21)
Magnetic resonance studies of protein-small molecule interactions. Dynamics of binding between N-trifluoroacetyl-D-tryptophan and -chymotrypsin. (1972) (21)
A totally synthetic histidine-2 ferredoxin: thermal stability and redox properties. (1991) (20)
Secondary isotope effects in the dehydration of malic acid by fumarate hydratase. (1969) (20)
The Acid-Catalyzed Cyclization of Acyclic Dienes (1964) (20)
Mechanism of action of coenzyme B 12 . Hydrogen transfer in the isomerization of -methylaspartate to glutamate. (1972) (20)
Cloning, heterologous expression, and characterization of recombinant class II cytochromes c from Rhodopseudomonas palustris. (2003) (20)
Studies on the catalytic mechanism of pepsin using a new synthetic substrate. (1972) (19)
Solvolysis of heteroannularly substituted methylferrocenylcarbinyl acetates (1968) (19)
Axial ligand modulation of the electronic structures of binuclear copper sites: analysis of paramagnetic 1H NMR spectra of Met160Gln Cu(A). (2001) (18)
Prevention of aggregation of synthetic membrane-spanning peptides by addition of detergent. (1988) (18)
Elements Of Organic Chemistry (1966) (17)
The Biosynthesis of the Triterpene, Eburicoic Acid: The Utilization of Methyl-labeled Acetate (1957) (17)
Spin delocalization over type zero copper. (2012) (17)
13C NMR studies of the binding of soybean trypsin inhibitor to trypsin. (1979) (17)
The beta-adrenergic receptor in the human neutrophil plasma membrane: receptor-cyclase uncoupling is associated with amplified GTP activation. (1984) (17)
Mutations of the Weak Axial Ligand in the Thermus CuA Center Modulates Its Electronic Structure (1999) (17)
The mechanism of the photochemical rearrangement of lumisantonin (1968) (17)
Metallocenyl carbonium ions. Stereochemistry of participation by ferrocene in the solvolysis of 2-ferrocenylalkyl tosylates (1969) (17)
Long Range Splittings in the NMR Spectra of Isomeric 2-Bromo-2-butenes (1961) (17)
Purification and subunit characterization of propanediol dehydratase, a membrane-associated enzyme. (1981) (17)
Magnetic resonance studies of the binding site interactions between 19F-labeled nitrophenyl haptens and specific mouse myeloma immunoglobulin MOPC-315. (1978) (17)
Mechanism of action of adenosylcobalamin: 3-fluoro-1,2-propranediol as substrate for propanediol dehydrase--mechanistic implications. (1975) (17)
The biogenesis of phenazine pigments (1961) (16)
Substrate specificities in class A beta-lactamases: preference for penams vs. cephems. The role of residue 237. (1989) (16)
Conformational Studies of Various Hemoglobins by Natural-Abundance 13C NMR Spectroscopy (1972) (16)
Structure of the orange pigment from Pseudomonas aureofaciens (1967) (16)
The effect of suspending agents on the release of aspirin from aqueous suspensions in vitro (1979) (16)
Photosensitization by Ferrocene. Photochemistry of Higher Electronic Excited States (1965) (15)
Nuclear magnetic resonance spectra of ferrocenyl carbonium ions (1966) (14)
Kinetic Isotope Effects in Enzymic Reactions (1970) (13)
MECHANISM OF T1 RELAXATION IN 13CO COMPLEXED TO AN IRON PORPHYRIN: IMPLICATIONS FOR CO BONDING IN HEME PROTEINS (1983) (13)
Identification of receptor regulatory proteins, membrane glycoproteins, and functional characteristics of adenylate cyclase in vesicles derived from the human neutrophil. (1984) (13)
Substrates for fumarate hydratase. (1969) (13)
The Nature of the Alkyl Groups in Nidulin (1961) (12)
The Biosynthesis of the Triterpene, Eburicoic Acid (1956) (12)
The Synthesis of Bridged Ferrocene Derivatives with Functional Groups on the β-Carbon of the Bridge (1962) (12)
Physical characterization of a totally synthetic 2[4Fe-4S] clostridial ferredoxin (1991) (11)
The effects of various suspending agents on the bioavailabilities of aspirin and salicylic acid in the rabbit (1979) (11)
Stereospecificity and mechanism of adenosylcobalamin-dependent diol dehydratase. Catalysis and inactivation with meso- and dl-2,3-butanediols as substrates. (1979) (11)
THE BIOGENESIS OF THE MOLD TROPOLONES. (1960) (10)
Resonance Raman Spectroscopy of Met121Glu Azurin (2000) (10)
The effects of storage and of potassium iodide, urea, N-acetyl-cysteine and triton X-100 on the viscosity of bronchial mucus. (1974) (10)
The nature of the hydrogen migrations in the cyclization of squalene oxide to lanosterol. (1970) (10)
Effect of relative humidity on the rheologic properties of bronchial mucus. (1974) (10)
Diol dehydratase: N-terminal amino acid sequences and subunit stoichiometry. (1982) (9)
Electron-transfer studies with the CuA domain of Thermus thermophilus cytochrome ba3 (1996) (9)
Magnetic resonance studies of protein-small molecule interactions. Binding of N-trifluoroacetyl-D-(and L-)-tryptophan to -chymotrypsin. (1972) (9)
A placebo- and active comparator-controlled dose escalation study of the pharmacokinetics, pharmacodynamics, and safety of inhaled large porous particle (AIR®) epinephrine in normal volunteers (2004) (8)
Studies on C3ahu binding to human eosinophils: characterization of binding. (1984) (8)
Mechanism of action of coenzyme B 12 . Release of 5'-deoxyinosine on incubation of deoxyinosylcobalamin, 1,2-propanediol and propanediol dehydrase. (1971) (7)
Stereospecific syntheses of ferrocene derivatives with leaving groups .beta. to the metallocene (1969) (7)
Creation of a test plasmid for detecting G-C-to-T-A transversions by changing serine to arginine in the active site of beta-lactamase (1987) (7)
13C Nuclear magnetic resonance studies to the binding of isocyanides to various hemoglobins and myoglobins. (1978) (6)
Relation between structure and specificity of antibodies: nuclear magnetic resonance study of binding fluorine-19 labeled nitrophenyl haptens to myeloma immunoglobulins M315, M460, and X25. (1978) (6)
Studies on the in vitro release of theophylline from polyethylene glycol-polyvinyl acetate mixtures liquid filled into hard gelatin capsules (1996) (6)
Electron tunneling in Ru-modified His46Asp azurin. Coupling through the Cu ligands (1998) (6)
Chapter 24. In Vitro Mutagenesis:Relationships in Proteins Powerful New Techniques for Studying Structure-Function Relationships in Proteins (1983) (6)
Electronic Spectroscopy of Gold(I) Pseudomonasaeruginosa Azurin Derivatives. (1996) (6)
Kinetic and thermodynamic consequences of the removal of the Cys-77 – Cys-123 disulphide bond for the folding of TEM-1 β-lactamase (1996) (5)
Directed mutagenesis as a technique to study protein function: application to beta-lactamase. (1984) (5)
The Structure and Biosynthesis of Nidulin1,2 (1963) (5)
Binding Dynamics in Biological Systems. Interaction of MOPC-315 with ^(19)F Labelled Nitrophenyl Haptens (1980) (5)
Effects of excipients on the bioavailability of sodium salicylate from orally administered, oily suspensions. (1996) (5)
Communications-The Structure of Nidulin (1961) (4)
Studies on the variation in the viscosity of bronchial mucus and a technique for reducing such variation. (1974) (4)
Photoproducts form irradiation of lumisantonin in aprotic medium (1968) (3)
13C magnetic resonance studies of hemoglobin carbamylation. (1974) (2)
Proteins to Order Use of Synthetic DNA to Generate Site-Specific Mutations (1982) (2)
Electron transfer in azurin. (1993) (2)
Opening of ring B of lanosterol by Beckmann fission of a .gamma.-oxo-oxime tosylate (1968) (2)
Physical-organic chemistry (1968) (2)
Mössbauer effect in ferrocenylcarbonium ion (1967) (2)
Hydrogen transfer in catalysis by adenosylcobalamin-dependent diol dehydratase. (1979) (2)
Structure and Function in Biochemistry (1983) (2)
Destructive Photooxidation of Tris(Dibenzoylmethanato)Iron(III) (1974) (2)
N-acetyl-S-methylmalonylcysteamine, an inhibitor of methylmalonyl coenzyme A isomerase. (1968) (2)
Electron transfer in cytochromes C with chelated ruthenium(II) polypyridine complexes. (1993) (2)
Chapter 21 – ALKALOID BIOGENESIS (1965) (2)
Studies of Protein Function by Various Mutagenic Strategies: β‐Lactamase a (1984) (2)
Chapter 29 Progress Toward the Rational Study of Enzyme Structure-Function Relationships (1987) (1)
Conformation studies of various hemoglobins by natural-abundance 13 C NMR spectroscopy. (1972) (1)
Construction and characterization of an azurin analog for the purple copper site in (2005) (1)
The Structure and Biosynthesis of Nidulin (1963) (1)
Kinetics of drug dissolution and dialysis from suspension dosage forms (1979) (1)
Bioavailability studies on an orally administered, oily suspension of a water soluble drug. (1983) (1)
Progress Toward the Rational Study of Enzyme Structure-Function Relationships (1987) (1)
Site Saturation Mutagenesis of Active Site Residues of β-Lactamase (1987) (1)
Intramolecular electron transfer in azurin: Effects of ligand substitutions (1995) (0)
Nuclear Magnetic Resonance (N.M.R.) in Biochenistry. Applications to Enzyme Systems. RAYMOND A. DWEK. Clarendon (Oxford University Press), New York, 1973. xviii, 396 pp., illus. $25.75. Monographs on Physical Biochemistry (1974) (0)
Mutant Proteins--Enzymes to Hydrolyze Toxic Organophosphates. (1987) (0)
Correlations and genetic implications. (1978) (0)
Genesynthesis, expression, andmutagenesis ofthebluecopper proteins azurin andplastocyanin (1991) (0)
Expression and purification of the nonfunctional Met80Ala mutant of yeast iso-1-cytochrome c. (1993) (0)
The Biogenesis of the Triterpene Eburicoic Acid (1955) (0)
Studies of protein function by various mutagenic strategies: beta-lactamase. (1984) (0)
Table of Contents (1988) (0)
Nuclear magnetic resonance studies of 13 CO binding to various heme globins. (1972) (0)
The Effect of DPG and IHP on the Relative Thermodynamic Affinity for CO of the Subunits of Rabbit Hemoglobin (1982) (0)
Intramolecular electron transfer in azurin: Coupling through a β-sheet (1995) (0)
Ionization Behavior of the Histidine (0)
MECHANISM OF ACTION OF COENZYME B$sub 12$. HYDROGEN TRANSFER IN THE ISOMERIZATION OF $beta$-METHYLASPARTATE TO GLUTAMATE. (1972) (0)
Catalysis by Chimeric Proteins: Conversion of a β-lactamase to a D,D-Carboxypeptidase (1990) (0)
Site-saturation studies of f 8-lactamase : Production and characterization of mutant . 8-lactamases with all possible amino acid substitutions at residue 71 ( mutagenesis / enzymatic catalysis / protein structure-function relationships / protein stability ) (2003) (0)
Biopolymers: Proteins and Nucleic Acids. (1990) (0)
Simulation of the effects of gastrointestinal transit rate on drug availability from aspirin suspensions using a modified dialysis method (1979) (0)
Altering enzymatic activity : Recruitment of carboxypeptidase activity into an RTEM f 3-lactamase / penicillin-binding protein 5 chimera ( mutagenesis / protein structure-function relatlonships / enzymatic catalysis ) (0)
Elements of Organic Chemistry/John H. Richards (1967) (0)
Molecular Characterization of Chlamydomonas Reinhardtii, ac-208: A Plastocyanin-Less Mutant (1987) (0)
Biopolymers: protein and nucleic acids. Annual report, 15 September 1987-14 September 1988 (1988) (0)
Body function measurement device (1997) (0)
Turning a blue copper protein into a purple copper protein: Making protein analogs to the CuA site of cytochrome C oxidase and the copper center in nitrous oxide reductase (1995) (0)
Biopolymers: Protein and Nucleic Acids (1987) (0)
The Structure of Nidulin (1961) (0)
Plastocyanin Gene Synthesis, Expression, and Mutagenesis of the Blue Copper Proteins Azurin and (2006) (0)
ROLE OF ACETATE IN BIOSYNTHESIS. (1963) (0)
Electron-transfer studies on a ruthenated [histidine-62] cytochrome c mutant (1989) (0)
Electron tunneling through mutant azurins on mixed SAM gold electrodes (2010) (0)
Studies on C-Terminal Analysis (1989) (0)
Reactions Of Metallocenes (1964) (0)

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