John Ioannidis
#4,170
Most Influential Person Now
Professor and chairman at the Department of Hygiene and Epidemiology
Why Is John Ioannidis Influential?
(Suggest an Edit or Addition)According to Wikipedia, John P. A. Ioannidis is a Greek-American physician-scientist, writer and Stanford University professor who has made contributions to evidence-based medicine, epidemiology, and clinical research. Ioannidis studies scientific research itself, meta-research primarily in clinical medicine and the social sciences.
John Ioannidis's Published Works
Published Works
- The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration (2009) (20340)
- The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration (2009) (13688)
- The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. (2009) (7631)
- Why Most Published Research Findings Are False (2005) (7320)
- Power failure: why small sample size undermines the reliability of neuroscience (2013) (5500)
- Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials (2011) (4355)
- The PRISMA Extension Statement for Reporting of Systematic Reviews Incorporating Network Meta-analyses of Health Care Interventions: Checklist and Explanations (2015) (3720)
- The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. (2009) (3700)
- Genome-wide association studies for complex traits: consensus, uncertainty and challenges (2008) (2939)
- Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): Explanation and Elaboration (2015) (2626)
- Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. (2011) (2348)
- A manifesto for reproducible science (2017) (1958)
- Replication validity of genetic association studies (2001) (1919)
- Redefine statistical significance (2017) (1806)
- Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis (2018) (1627)
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease (2014) (1591)
- Contradicted and initially stronger effects in highly cited clinical research. (2005) (1393)
- Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias (2008) (1390)
- The case of the misleading funnel plot (2006) (1340)
- Why Most Discovered True Associations Are Inflated (2008) (1159)
- Why Most Published Research Findings Are False (2005) (1149)
- Increasing value and reducing waste in research design, conduct, and analysis (2014) (1144)
- Better Reporting of Harms in Randomized Trials: An Extension of the CONSORT Statement (2004) (1135)
- Genome-wide meta-analyses identify multiple loci associated with smoking behavior (2010) (1107)
- How to increase value and reduce waste when research priorities are set (2014) (1064)
- Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database (2008) (1064)
- Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture (2012) (1045)
- Uncertainty in heterogeneity estimates in meta-analyses (2007) (984)
- Evaluation of networks of randomized trials (2008) (945)
- The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method (2014) (937)
- Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis (2012) (885)
- Neoadjuvant versus adjuvant systemic treatment in breast cancer: a meta-analysis. (2005) (874)
- Influence of Reported Study Design Characteristics on Intervention Effect Estimates From Randomized, Controlled Trials (2012) (871)
- The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey (2007) (863)
- The Mass Production of Redundant, Misleading, and Conflicted Systematic Reviews and Meta-analyses. (2016) (848)
- Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials (2014) (831)
- What does research reproducibility mean? (2016) (829)
- Comparison of evidence of treatment effects in randomized and nonrandomized studies. (2001) (815)
- Plea for routinely presenting prediction intervals in meta-analysis (2016) (767)
- Reproducibility in Science: Improving the Standard for Basic and Preclinical Research (2015) (757)
- Seven New Loci Associated with Age-Related Macular Degeneration (2013) (741)
- Heterogeneity testing in meta‐analysis of genome searches (2005) (724)
- Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation. (2008) (713)
- EULAR recommendations for the management of systemic lupus erythematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (2007) (698)
- Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies (2009) (687)
- Summing up evidence: one answer is not always enough (1998) (672)
- Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses? (2009) (658)
- How to Make More Published Research True (2014) (619)
- Genetic associations in large versus small studies: an empirical assessment (2003) (611)
- Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trials. (1998) (600)
- EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases (2010) (599)
- EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs (2010) (595)
- Demystifying trial networks and network meta-analysis (2013) (581)
- Assessment of cumulative evidence on genetic associations: interim guidelines. (2008) (559)
- Meta-analysis in genome-wide association studies. (2009) (559)
- Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database (2012) (546)
- Opportunities and challenges in developing risk prediction models with electronic health records data: a systematic review (2017) (545)
- Repeatability of published microarray gene expression analyses (2009) (543)
- A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy (2000) (543)
- Evidence-based de-implementation for contradicted, unproven, and aspiring healthcare practices (2014) (532)
- An exploratory test for an excess of significant findings (2007) (529)
- Type 2 diabetes and cancer: umbrella review of meta-analyses of observational studies (2015) (528)
- COVID-19 Antibody Seroprevalence in Santa Clara County, California (2020) (515)
- Meta-analysis methods for genome-wide association studies and beyond (2013) (506)
- Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease. (2006) (505)
- Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement (2009) (494)
- The Proposal to Lower P Value Thresholds to .005. (2018) (491)
- Differential Effects of NOD2 Variants on Crohn's Disease Risk and Phenotype in Diverse Populations: A Metaanalysis (2004) (488)
- STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement (2009) (482)
- Clinical evolution, and morbidity and mortality of primary Sjögren's syndrome. (2000) (473)
- Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses (2015) (472)
- HEGESMA: genome search meta-analysis and heterogeneity testing (2005) (472)
- Relative citation impact of various study designs in the health sciences. (2005) (472)
- Correlation of quality measures with estimates of treatment effect in meta-analyses of randomized controlled trials. (2002) (469)
- 'Racial' differences in genetic effects for complex diseases (2004) (461)
- Long-term risk of mortality and lymphoproliferative disease and predictive classification of primary Sjögren's syndrome. (2002) (453)
- Biomedical research: increasing value, reducing waste (2014) (448)
- Percutaneous Coronary Intervention Versus Conservative Therapy in Nonacute Coronary Artery Disease: A Meta-Analysis (2005) (446)
- Artificial intelligence versus clinicians: systematic review of design, reporting standards, and claims of deep learning studies (2020) (444)
- Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial (2018) (442)
- Why Current Publication Practices May Distort Science (2008) (442)
- Empirical assessment of published effect sizes and power in the recent cognitive neuroscience and psychology literature (2017) (441)
- Mortality in systemic sclerosis: an international meta-analysis of individual patient data. (2005) (435)
- Why Science Is Not Necessarily Self-Correcting (2012) (433)
- Nationwide Population Science: Lessons From the Taiwan National Health Insurance Research Database. (2015) (431)
- Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study (2013) (426)
- Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal (2010) (417)
- Single or multiple daily doses of aminoglycosides: a meta- analysis (1996) (415)
- Interpretation of tests of heterogeneity and bias in meta-analysis. (2008) (415)
- Why Most Clinical Research Is Not Useful (2016) (413)
- Integration of evidence from multiple meta-analyses: a primer on umbrella reviews, treatment networks and multiple treatments meta-analyses (2009) (410)
- Treating anemia early in renal failure patients slows the decline of renal function: a randomized controlled trial. (2004) (403)
- The Power of Bias in Economics Research (2017) (401)
- Validating, augmenting and refining genome-wide association signals (2009) (394)
- Publication and other reporting biases in cognitive sciences: detection, prevalence, and prevention (2014) (392)
- Perinatal transmission of human immunodeficiency virus type 1 by pregnant women with RNA virus loads <1000 copies/ml. (2001) (389)
- Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study (2012) (382)
- Reasons or excuses for avoiding meta-analysis in forest plots (2008) (380)
- Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder: observational follow-up study (2006) (370)
- Clinical interpretation and implications of whole-genome sequencing. (2014) (365)
- Meta-Analysis: Test Performance of Ultrasonography for Giant-Cell Arteritis (2005) (353)
- How to read a systematic review and meta-analysis and apply the results to patient care: users' guides to the medical literature. (2014) (352)
- What causes psychosis? An umbrella review of risk and protective factors (2018) (352)
- Hardy–Weinberg equilibrium in genetic association studies: an empirical evaluation of reporting, deviations, and power (2005) (350)
- Predictive ability of DNA microarrays for cancer outcomes and correlates: an empirical assessment (2003) (348)
- Standard 6: Age Groups for Pediatric Trials (2012) (347)
- How to use a subgroup analysis: users' guide to the medical literature. (2014) (347)
- How to use an article reporting a multiple treatment comparison meta-analysis. (2012) (345)
- Early extreme contradictory estimates may appear in published research: the Proteus phenomenon in molecular genetics research and randomized trials. (2005) (332)
- The infection fatality rate of COVID-19 inferred from seroprevalence data (2020) (332)
- Heterogeneity in Meta-Analyses of Genome-Wide Association Investigations (2007) (328)
- Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomized clinical trial. (2013) (325)
- Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes. (2004) (324)
- PRISMA harms checklist: improving harms reporting in systematic reviews (2016) (323)
- Maintenance antiretroviral therapies in HIV-infected subjects with undetectable plasma HIV RNA after triple-drug therapy. AIDS Clinical Trials Group Study 343 Team. (1998) (316)
- 18F-fluorodeoxyglucose positron emission tomography to evaluate cervical node metastases in patients with head and neck squamous cell carcinoma: a meta-analysis. (2008) (315)
- Public Availability of Published Research Data in High-Impact Journals (2011) (311)
- Genetic associations: false or true? (2003) (301)
- Translation of highly promising basic science research into clinical applications. (2003) (300)
- Coronavirus disease 2019: The harms of exaggerated information and non‐evidence‐based measures (2020) (299)
- Evolution of Reporting P Values in the Biomedical Literature, 1990-2015. (2016) (299)
- Recommendations for Biomarker Identification and Qualification in Clinical Proteomics (2010) (298)
- Big data meets public health (2014) (293)
- Microarrays and molecular research: noise discovery? (2005) (284)
- Impact of violations and deviations in Hardy-Weinberg equilibrium on postulated gene-disease associations. (2006) (283)
- Effects of CCR5- 32, CCR2-64I, and SDF-1 3A Alleles on HIV-1 Disease Progression: An International Meta-Analysis of Individual-Patient Data (2001) (282)
- Excess significance bias in the literature on brain volume abnormalities. (2011) (281)
- Statins decrease perioperative cardiac complications in patients undergoing noncardiac vascular surgery: the Statins for Risk Reduction in Surgery (StaRRS) study. (2005) (278)
- Environmental risk factors and Parkinson's disease: An umbrella review of meta-analyses. (2016) (277)
- The False-positive to False-negative Ratio in Epidemiologic Studies (2011) (276)
- Mortality risk conferred by small elevations of creatine kinase-MB isoenzyme after percutaneous coronary intervention. (2003) (274)
- A universal standard for the validation of blood pressure measuring devices: Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Collaboration Statement. (2018) (273)
- Enhancing reproducibility for computational methods (2016) (273)
- What Other Countries Can Learn From Italy During the COVID-19 Pandemic. (2020) (273)
- Assessment of claims of improved prediction beyond the Framingham risk score. (2009) (271)
- The Challenge of Reforming Nutritional Epidemiologic Research. (2018) (270)
- Collaborative Meta-analysis: Associations of 150 Candidate Genes With Osteoporosis and Osteoporotic Fracture (2009) (267)
- Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases. (2006) (266)
- Comparisons of established risk prediction models for cardiovascular disease: systematic review (2012) (266)
- Issues in comparisons between meta-analyses and large trials. (1998) (265)
- Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration (2011) (264)
- Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. (2008) (262)
- Non-Replication and Inconsistency in the Genome-Wide Association Setting (2007) (261)
- What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations. (2012) (260)
- Replication in genome-wide association studies. (2009) (258)
- External validation of new risk prediction models is infrequent and reveals worse prognostic discrimination. (2015) (257)
- The Association between Common Vitamin D Receptor Gene Variations and Osteoporosis: A Participant-Level Meta-Analysis (2006) (254)
- A road map for efficient and reliable human genome epidemiology (2006) (252)
- Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case–control study (2011) (246)
- Meta-assessment of bias in science (2017) (246)
- Reproducible Research Practices and Transparency across the Biomedical Literature (2016) (243)
- 18F-FDG PET for evaluation of bone marrow infiltration in staging of lymphoma: a meta-analysis. (2005) (243)
- Comparison of evidence on harms of medical interventions in randomized and nonrandomized studies (2006) (242)
- Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases (2013) (242)
- Population-level COVID-19 mortality risk for non-elderly individuals overall and for non-elderly individuals without underlying diseases in pandemic epicenters (2020) (242)
- Forecasting for COVID-19 has failed (2020) (241)
- Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses. (2011) (240)
- Implausible results in human nutrition research (2013) (239)
- Methodological standards and patient-centeredness in comparative effectiveness research: the PCORI perspective. (2012) (239)
- Prognostic Significance of Vascular Endothelial Growth Factor Immunohistochemical Expression in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis (2005) (238)
- Improving Validation Practices in “Omics” Research (2011) (235)
- The Emergence of Translational Epidemiology: From Scientific Discovery to Population Health Impact (2010) (235)
- Assessing scientists for hiring, promotion, and tenure (2018) (231)
- A meta-analysis of the relative efficacy and toxicity of Pneumocystis carinii prophylactic regimens. (1996) (230)
- Selective reporting biases in cancer prognostic factor studies. (2005) (228)
- Effectiveness of antidepressants: an evidence myth constructed from a thousand randomized trials? (2008) (226)
- Clinical outcome prediction by microRNAs in human cancer: a systematic review. (2012) (224)
- Reporting and interpretation of SF-36 outcomes in randomised trials: systematic review (2009) (223)
- Association of Polymorphisms of the Estrogen Receptor α Gene With Bone Mineral Density and Fracture Risk in Women: A Meta‐Analysis (2002) (220)
- Benzodiazepines for alcohol withdrawal. (2005) (216)
- Exploring the Geometry of Treatment Networks (2008) (216)
- Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study (2015) (214)
- Empirical evaluation of very large treatment effects of medical interventions. (2012) (214)
- Adverse events in randomized trials: neglected, restricted, distorted, and silenced. (2009) (214)
- Role of the Fcgamma receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis. (2002) (214)
- STrengthening the Reporting of OBservational studies in Epidemiology – Molecular Epidemiology (STROBE-ME): An Extension of the STROBE Statement (2011) (214)
- Remission, relapse, and re-remission of proliferative lupus nephritis treated with cyclophosphamide. (2000) (213)
- Almost all articles on cancer prognostic markers report statistically significant results. (2007) (212)
- Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis. (2006) (211)
- A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. (2010) (210)
- Persistence of contradicted claims in the literature. (2007) (209)
- Meta-research: Evaluation and Improvement of Research Methods and Practices (2015) (208)
- When Null Hypothesis Significance Testing Is Unsuitable for Research: A Reassessment (2016) (208)
- Accuracy of anti-ribosomal P protein antibody testing for the diagnosis of neuropsychiatric systemic lupus erythematosus: an international meta-analysis. (2006) (205)
- Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. (2009) (203)
- Methods for meta-analysis in genetic association studies: a review of their potential and pitfalls (2008) (203)
- Life Cycle of Translational Research for Medical Interventions (2008) (199)
- More than a billion people taking statins?: Potential implications of the new cardiovascular guidelines. (2014) (198)
- The Scientific Foundation for Personal Genomics: Recommendations from a National Institutes of Health–Centers for Disease Control and Prevention Multidisciplinary Workshop (2009) (196)
- Evidence-based medicine has been hijacked: a report to David Sackett. (2016) (196)
- Evidence Relating Health Care Provider Burnout and Quality of Care (2019) (195)
- Physical examination (2003) (194)
- Clinically Significant and Biopsy‐Documented Renal Involvement in Primary Sjogren Syndrome (2000) (193)
- Machine learning and artificial intelligence research for patient benefit: 20 critical questions on transparency, replicability, ethics, and effectiveness (2020) (192)
- Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19: A Systematic Review and Meta-analysis. (2021) (190)
- Health outcomes during the 2008 financial crisis in Europe: systematic literature review (2016) (188)
- Reversals of established medical practices: evidence to abandon ship. (2012) (188)
- Systematic evaluation of the associations between environmental risk factors and dementia: An umbrella review of systematic reviews and meta-analyses (2017) (188)
- Rethinking recommendations for screening for depression in primary care (2012) (188)
- 18F-FDG PET for the diagnosis and grading of soft-tissue sarcoma: a meta-analysis. (2003) (185)
- Large-Scale Evidence for the Effect of the COLIA1 Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS Study (2006) (185)
- Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials (2020) (184)
- Overlapping meta-analyses on the same topic: survey of published studies (2013) (182)
- Prevalence and outcomes of incidental imaging findings: umbrella review (2018) (181)
- Meta-analysis of fractional flow reserve versus quantitative coronary angiography and noninvasive imaging for evaluation of myocardial ischemia. (2007) (180)
- Local Literature Bias in Genetic Epidemiology: An Empirical Evaluation of the Chinese Literature (2005) (179)
- Drivers of poor medical care (2017) (177)
- Intravenous glycoprotein IIb/IIIa receptor antagonists reduce mortality after percutaneous coronary interventions. (2003) (177)
- Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis. (2007) (174)
- Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis (2015) (173)
- UCHL1 is a Parkinson's disease susceptibility gene (2004) (173)
- Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study (2015) (172)
- The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance (2010) (172)
- How to use an article about genetic association: B: Are the results of the study valid? (2009) (171)
- Reanalyses of randomized clinical trial data. (2014) (170)
- Screening performance of first-trimester nuchal translucency for major cardiac defects: a meta-analysis. (2003) (168)
- Optimal timing of coronary angiography and potential intervention in non-ST-elevation acute coronary syndromes. (2011) (168)
- Small studies are more heterogeneous than large ones: a meta-meta-analysis. (2015) (168)
- Extended-interval aminoglycoside administration for children: a meta-analysis. (2004) (167)
- Prognostic factors and outcomes for osteosarcoma: an international collaboration. (2009) (167)
- Transparency and reproducibility in artificial intelligence (2020) (167)
- Lack of evidence to favor specific preventive interventions in psychosis: a network meta‐analysis (2018) (166)
- A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility. (2009) (164)
- Survival and disease-progression benefits with treatment regimens for advanced colorectal cancer: a meta-analysis. (2007) (164)
- A standardized citation metrics author database annotated for scientific field (2019) (163)
- CTLA-4 gene polymorphisms and susceptibility to type 1 diabetes mellitus: a HuGE Review and meta-analysis. (2005) (162)
- Physical activity and cancer: an umbrella review of the literature including 22 major anatomical sites and 770 000 cancer cases (2017) (162)
- Technical aspects and inter-laboratory variability in native peptide profiling: the CE-MS experience. (2013) (161)
- Meta‐Analysis of Genome‐Wide Scans Provides Evidence for Sex‐ and Site‐Specific Regulation of Bone Mass (2006) (161)
- Assessment of vibration of effects due to model specification can demonstrate the instability of observational associations. (2015) (161)
- Inadequacies of Physical Examination as a Cause of Medical Errors and Adverse Events: A Collection of Vignettes. (2015) (159)
- How does exercise treatment compare with antihypertensive medications? A network meta-analysis of 391 randomised controlled trials assessing exercise and medication effects on systolic blood pressure (2018) (159)
- Metformin Does Not Affect Cancer Risk: A Cohort Study in the U.K. Clinical Practice Research Datalink Analyzed Like an Intention-to-Treat Trial (2014) (158)
- Effect sizes in cumulative meta-analyses of mental health randomized trials evolved over time. (2004) (156)
- Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22 (2010) (156)
- Is everything we eat associated with cancer? A systematic cookbook review. (2013) (155)
- Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer. (2010) (155)
- Implementation of proteomic biomarkers: making it work (2012) (155)
- Reproducible research practices, transparency, and open access data in the biomedical literature, 2015–2017 (2018) (154)
- Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey (2016) (153)
- Ensuring the integrity of clinical practice guidelines: a tool for protecting patients (2013) (153)
- Cyclophosphamide with low or high dose prednisolone for systemic sclerosis lung disease. (2002) (152)
- Meta-analysis of the association of beta2-adrenergic receptor polymorphisms with asthma phenotypes. (2005) (152)
- Research grants: Conform and be funded (2012) (150)
- Intravenous immunoglobulin compared with cyclophosphamide for proliferative lupus nephritis (1999) (149)
- Narrow band imaging to differentiate neoplastic and non-neoplastic colorectal polyps in real time: a meta-analysis of diagnostic operating characteristics (2013) (149)
- Radiotherapy vs. nonsteroidal anti-inflammatory drugs for the prevention of heterotopic ossification after major hip procedures: a meta-analysis of randomized trials. (2004) (148)
- Design and analysis of metabolomics studies in epidemiologic research: a primer on -omic technologies. (2014) (147)
- Nuchal translucency and fetal cardiac defects: a pooled analysis of major fetal echocardiography centers. (2005) (144)
- Expectant, Medical, or Surgical Management of First-Trimester Miscarriage: A Meta-Analysis (2005) (144)
- Genome-Wide Association Studies, Field Synopses, and the Development of the Knowledge Base on Genetic Variation and Human Diseases (2009) (144)
- The Fc gamma RIIIA-F158 allele is a risk factor for the development of lupus nephritis: a meta-analysis. (2003) (143)
- Claims of sex differences: an empirical assessment in genetic associations. (2007) (142)
- Data sharing and reanalysis of randomized controlled trials in leading biomedical journals with a full data sharing policy: survey of studies published in The BMJ and PLOS Medicine (2018) (142)
- Real-world evidence: How pragmatic are randomized controlled trials labeled as pragmatic? (2018) (141)
- Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses (2020) (141)
- Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer. (2008) (141)
- Survival benefits with diverse chemotherapy regimens for ovarian cancer: meta-analysis of multiple treatments. (2006) (141)
- Impact of Schizophrenia Candidate Genes on Schizotypy and Cognitive Endophenotypes at the Population Level (2007) (140)
- Origin and funding of the most frequently cited papers in medicine: database analysis (2006) (140)
- Head-to-head randomized trials are mostly industry sponsored and almost always favor the industry sponsor. (2015) (140)
- STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement. (2011) (140)
- Infection fatality rate of COVID-19 inferred from seroprevalence data (2020) (140)
- Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies. (2018) (139)
- Vaccination in adult patients with auto-immune inflammatory rheumatic diseases: a systematic literature review for the European League Against Rheumatism evidence-based recommendations for vaccination in adult patients with auto-immune inflammatory rheumatic diseases. (2011) (139)
- Materializing research promises: opportunities, priorities and conflicts in translational medicine (2004) (138)
- A heterogeneity-based genome search meta-analysis for autism-spectrum disorders (2006) (138)
- Autoimmune hemolytic anemia in patients with systemic lupus erythematosus. (2000) (138)
- Understanding and harnessing the health effects of rapid urbanization in China. (2011) (138)
- Statistically significant meta-analyses of clinical trials have modest credibility and inflated effects. (2011) (138)
- Double Versus Single Stenting for Coronary Bifurcation Lesions: A Meta-Analysis (2009) (137)
- p-Curve and p-Hacking in Observational Research (2016) (137)
- Anaemia in systemic lupus erythematosus: aetiological profile and the role of erythropoietin (2000) (137)
- Assessing mandatory stay‐at‐home and business closure effects on the spread of COVID‐19 (2021) (136)
- Association of GSTM1, GSTT1, and GSTP1 gene polymorphisms with the risk of prostate cancer: a meta-analysis. (2005) (135)
- Meta‐research: The art of getting it wrong (2010) (135)
- Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data. (2001) (133)
- Large-scale replication and heterogeneity in Parkinson disease genetic loci (2012) (133)
- Limitations are not properly acknowledged in the scientific literature. (2007) (132)
- On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies. (2007) (132)
- A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip (2013) (132)
- The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement (2019) (132)
- Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study (2010) (131)
- Is molecular profiling ready for use in clinical decision making? (2007) (130)
- Electrocardiogram-gated single-photon emission computed tomography versus cardiac magnetic resonance imaging for the assessment of left ventricular volumes and ejection fraction: a meta-analysis. (2002) (129)
- Meta-analysis methods. (2008) (129)
- Next-generation systematic reviews: prospective meta-analysis, individual-level data, networks and umbrella reviews (2017) (129)
- Evolution and Translation of Research Findings: From Bench to Where? (2006) (128)
- Atherosclerosis in premenopausal women with antiphospholipid syndrome and systemic lupus erythematosus: a controlled study. (2003) (125)
- Are amoxycillin and folate inhibitors as effective as other antibiotics for acute sinusitis? A meta-analysis (1998) (125)
- US studies may overestimate effect sizes in softer research (2013) (124)
- Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels (2012) (124)
- Meta-research: Why research on research matters (2018) (123)
- A Nutrient-Wide Association Study on Blood Pressure (2012) (122)
- Exploration, Inference, and Prediction in Neuroscience and Biomedicine (2019) (121)
- A network of investigator networks in human genome epidemiology. (2005) (121)
- Thousands of scientists publish a paper every five days (2018) (121)
- Required sample size and nonreplicability thresholds for heterogeneous genetic associations (2008) (119)
- How to use an article about genetic association: A: Background concepts. (2009) (118)
- Recalibrating the Use of Race in Medical Research. (2021) (118)
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- Perspective: Limiting Dependence on Nonrandomized Studies and Improving Randomized Trials in Human Nutrition Research: Why and How. (2018) (56)
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- Perspective: Improving Nutritional Guidelines for Sustainable Health Policies: Current Status and Perspectives (2017) (54)
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- Reproducibility: Has Cancer Biology Failed beyond Repair? (2022) (0)
- Twitter and Mastodon presence of highly-cited scientists (2023) (0)
- ‘Stealth’ corporate innovation: an emerging threat for therapeutic drug development (2019) (0)
- HUMAN GENOME EPIDEMIOLOGY (HuGE) REVIEW CTLA-4 Gene Polymorphisms and Susceptibility to Type 1 Diabetes Mellitus: A HuGE Review and Meta-Analysis (2005) (0)
- Evaluating cumulative evidence in genomic epidemiology (2008) (0)
- Science, advocacy, and quackery in nutritional books: an analysis of conflicting advice and purported claims of nutritional best-sellers (2020) (0)
- Re: Priority setting in research (2017) (0)
- Assessing the usefulness of randomized trials in obstetrics and gynaecology. (2023) (0)
- How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation (2018) (0)
- Mapping the universe of registered reports (2018) (0)
- Reproducible pharmacokinetics (2019) (0)
- Published Registry-Based Pharmacoepidemiologic Associations Show Limited Concordance with Agnostic Medication-Wide Analyses (2023) (0)
- Excess death estimates from multiverse analysis in 2009–2021 (2023) (0)
- Federal Funding and Citation Metrics of US Biomedical Researchers, 1996 to 2022 (2022) (0)
- The Great Disruption: COVID-19 and the Global Health Crisis (2020) (0)
- How do we increase the trustworthiness of medical publications? (2023) (0)
- Transparency in infectious disease research: a meta-research survey of specialty journals (2022) (0)
- polymorphisms and hematologic and autoimmune diseases receptor gene γ Meta-analysis of the association between low-affinityFc (2013) (0)
- Impact of changing the threshold of statistical significance to P lower than 0.005 on recommended medical interventions (2018) (0)
- Machine learning augmentation reduces prediction error in collective forecasting: development and validation across prediction markets (2023) (0)
- 96 Evaluation of predictors and impact of losses to follow-up in the domain of hiv infection (1997) (0)
- Contents Vol. 64, 2007 (2007) (0)
- An umbrella review of systematic reviews on the impact of the COVID-19 pandemic on cancer prevention and management, and patient needs (2023) (0)
- Functional characterization of GWAS loci associated with fracture risk (2013) (0)
- Reproducibility in the UK biobank of genome-wide significant signals discovered in earlier genome-wide association studies (2021) (0)
- Author Correction: ‘Stealth’ corporate innovation: an emerging threat for therapeutic drug development (2019) (0)
- Feasibility indicators in obesity-related behavioral intervention preliminary studies: a historical scoping review (2023) (0)
- PREVIOUS SYSTEMATIC REVIEWS (2002) (0)
- Individual participant data meta-analysis to compare EPDS accuracy to detect major depression with and without the self-harm item (2023) (0)
- Verdi-paper (2018) (0)
- Ten (not so) simple rules for clinical trial data-sharing (2023) (0)
- Estimates of COVID-19 deaths in Mainland China after abandoning zero COVID policy (2022) (0)
- THE arcOGEN CONSORTIUM: STAGE 1 OF A GENOME-WIDE ASSOCIATION SCAN FOR OSTEOARTHRITIS (2010) (0)
- Medical advertisements and scientific journals: Time for editors and publishers to take a stance. (2023) (0)
- COVID-19 models and expectations – Learning from the pandemic (2022) (0)
- "Misfearing" —Culture,Identity,andOurPerceptions ofHealthRisks (2014) (0)
- mpact of Schizophrenia Candidate Genes on chizotypy and Cognitive Endophenotypes at the opulation Level (2007) (0)
- CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomized trials. (2023) (0)
- Validation and Confirmation of Associations (2008) (0)
- Incidence, Risk, and Severity of SARS-CoV-2 Reinfections in Children and Adolescents Between March 2020 and July 2022 in Serbia (2023) (0)
- Implementation of proteomic biomarkers: making it work PERSPECTIVE (2012) (0)
- Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance (2015) (0)
- Age-stratified infection fatality rate of COVID-19 in the non-elderly informed from pre-vaccination national seroprevalence studies (2022) (0)
- Redefine statistical significance (2017) (0)
- Corrigendum: Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example (2015) (0)
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