John R. Riordan

Q: What Schools Are Affiliated With John R. Riordan

John R. Riordan is affiliated with the following schools: Université libre de Bruxelles, McGill University, University of Oxford, California Institute of Technology, University of Toronto, University of North Carolina at Chapel Hill

John R. Riordan's AcademicInfluence.com Rankings

John R. Riordan

Biology

#3944

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#5956

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Biochemistry

#522

World Rank

#610

Historical Rank

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Biology

Why Is John R. Riordan Influential?

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According to Wikipedia, John Richard Riordan, OC is a Canadian biochemist, noted for his research into cystic fibrosis. After acquiring his bachelor's degree in 1966 from the University of Toronto, he studied and received a doctorate in biochemistry from the same university in 1970. His next three years were spent at the Max Planck Institute for Biophysics in Frankfurt. He then returned to the University of Toronto, where he worked as a professor in the Biochemistry department from 1974. Prior to retiring in 2018, Riordan was a professor at the University of North Carolina at Chapel Hill where he was a member of the Biochemistry and Biophysics Department studying the structure and function of CFTR. He is also a visiting scientist at the Academy Salhgrenska and University of Gothenburg.

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John R. Riordan's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Erratum: Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA (1989) (4149)
Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. (1989) (3650)
Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. (1983) (969)
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing (1995) (914)
Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR) (1992) (914)
Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines (1985) (812)
CFTR function and prospects for therapy. (2008) (592)
Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis (2006) (591)
Genomic DNA sequence of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. (1991) (537)
Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene (1991) (498)
Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance (1991) (457)
Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene. (1990) (421)
Genetic and biochemical characterization of multidrug resistance. (1985) (418)
The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein. (1986) (417)
Phenylalanine-508 mediates a cytoplasmic–membrane domain contact in the CFTR 3D structure crucial to assembly and channel function (2008) (393)
Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome (1998) (387)
Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability. (1979) (381)
The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells. (1993) (377)
Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator. (1994) (370)
Mislocalization of ΔF508 CFTR in cystic fibrosis sweat gland (1992) (268)
Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. (2005) (259)
Assembly of functional CFTR chloride channels. (2005) (259)
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. (2010) (244)
COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit code (2004) (241)
Multi-ion pore behaviour in the CFTR chloride channel (1993) (234)
Permeability of Wild-Type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels to Polyatomic Anions (1997) (234)
Daunorubicin-resistant Chinese hamster ovary cells expressing multidrug resistance and a cell-surface P-glycoprotein. (1983) (232)
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration (2012) (225)
Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator. (2004) (221)
Domain interdependence in the biosynthetic assembly of CFTR. (2007) (215)
Multidrug-resistance phenotype in Chinese hamster ovary cells. (1983) (207)
Non-conventional Trafficking of the Cystic Fibrosis Transmembrane Conductance Regulator through the Early Secretory Pathway* (2002) (204)
DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression (1982) (203)
Mutation analysis for heterozygote detection and the prenatal diagnosis of cystic fibrosis. (1990) (199)
Assignment of the gene for myelin proteolipid protein to the X chromosome: implications for X-linked myelin disorders. (1985) (198)
The First Nucleotide Binding Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is a Site of Stable Nucleotide Interaction, whereas the Second Is a Site of Rapid Turnover* (2002) (191)
Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene. (1991) (187)
Removal of multiple arginine-framed trafficking signals overcomes misprocessing of delta F508 CFTR present in most patients with cystic fibrosis. (1999) (165)
Voltage-dependent block of the cystic fibrosis transmembrane conductance regulator Cl- channel by two closely related arylaminobenzoates (1993) (157)
Inhibition of epithelial Na+ currents by intracellular domains of the cystic fibrosis transmembrane conductance regulator (1997) (151)
Synthetic and natural opiates interact with P-glycoprotein in multidrug-resistant cells. (1993) (148)
ATPase Activity of Purified Multidrug Resistance-associated Protein* (1997) (146)
Purification and Crystallization of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)* (2004) (143)
Allosteric Interactions between the Two Non-equivalent Nucleotide Binding Domains of Multidrug Resistance Protein MRP1* (2000) (143)
Direct action of genistein on CFTR (1997) (140)
Action of calcium antagonists on multidrug resistant cells. Specific cytotoxicity independent of increased cancer drug accumulation. (1987) (133)
The PDZ-binding Chloride Channel ClC-3B Localizes to the Golgi and Associates with Cystic Fibrosis Transmembrane Conductance Regulator-interacting PDZ Proteins* (2003) (130)
Correctors of ΔF508 CFTR restore global conformational maturation without thermally stabilizing the mutant protein (2013) (129)
Human fetal liver contains both zinc- and copper-rich forms of metallothionein. (1980) (120)
Disease-associated Mutations in the Fourth Cytoplasmic Loop of Cystic Fibrosis Transmembrane Conductance Regulator Compromise Biosynthetic Processing and Chloride Channel Activity* (1996) (120)
Multiple Membrane-Cytoplasmic Domain Contacts in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mediate Regulation of Channel Gating* (2008) (120)
Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator. (1994) (113)
Cystic fibrosis transmembrane conductance regulator degradation depends on the lectins Htm1p/EDEM and the Cdc48 protein complex in yeast. (2004) (111)
Cystic fibrosis as a disease of misprocessing of the cystic fibrosis transmembrane conductance regulator glycoprotein. (1999) (111)
Regulatory insertion removal restores maturation, stability and function of DeltaF508 CFTR. (2010) (111)
The DeltaF508 mutation results in loss of CFTR function and mature protein in native human colon. (2004) (110)
Cytoplasmic Loop Three of Cystic Fibrosis Transmembrane Conductance Regulator Contributes to Regulation of Chloride Channel Activity* (1996) (106)
Differential Interactions of Nucleotides at the Two Nucleotide Binding Domains of the Cystic Fibrosis Transmembrane Conductance Regulator* (2001) (104)
Mislocalization of delta F508 CFTR in cystic fibrosis sweat gland. (1992) (101)
cAMP-inducible chloride conductance in mouse fibroblast lines stably expressing the human cystic fibrosis transmembrane conductance regulator. (1991) (97)
Quantitative expression patterns of multidrug-resistance P-glycoprotein (MDR1) and differentially spliced cystic-fibrosis transmembrane-conductance regulator mRNA transcripts in human epithelia. (1992) (94)
Influence of phosphorylation by protein kinase A on CFTR at the cell surface and endoplasmic reticulum. (1999) (93)
Allosteric modulation balances thermodynamic stability and restores function of ΔF508 CFTR. (2012) (92)
CFTR (ABCC7) is a hydrolyzable-ligand-gated channel (2007) (91)
cAMP-dependent Protein Kinase-mediated Phosphorylation of Cystic Fibrosis Transmembrane Conductance Regulator Residue Ser-753 and Its Role in Channel Activation (*) (1995) (89)
Quantitation of mRNA by the kinetic polymerase chain reaction assay: a tool for monitoring P-glycoprotein gene expression. (1991) (88)
Chemical and Biological Folding Contribute to Temperature‐Sensitive ΔF508 CFTR Trafficking (2008) (87)
The non‐hydrolytic pathway of cystic fibrosis transmembrane conductance regulator ion channel gating (2000) (85)
Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator (2003) (85)
Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures. (2010) (81)
Differential regulation of single CFTR channels by PP2C, PP2A, and other phosphatases. (1998) (81)
Regulation of CFTR ion channel gating by MgATP (1998) (81)
Role of N-linked oligosaccharides in the biosynthetic processing of the cystic fibrosis membrane conductance regulator (2008) (78)
Traffic Pattern of Cystic Fibrosis Transmembrane Regulator through the Early Exocytic Pathway (2000) (78)
Phenotypic Abnormalities in Long-Term Surviving Cystic Fibrosis Mice (1996) (78)
Restoration of domain folding and interdomain assembly by second‐site suppressors of the ΔF508 mutation in CFTR (2010) (77)
Disease-associated mutations in cytoplasmic loops 1 and 2 of cystic fibrosis transmembrane conductance regulator impede processing or opening of the channel. (1997) (77)
Interactions of lectins with membrane glycoproteins. Effects of concanavalin A on 5'-nucleotidase. (1974) (73)
Dibasic protein kinase A sites regulate bursting rate and nucleotide sensitivity of the cystic fibrosis transmembrane conductance regulator chloride channel (1998) (72)
ATP Binding to the First Nucleotide-binding Domain of Multidrug Resistance Protein MRP1 Increases Binding and Hydrolysis of ATP and Trapping of ADP at the Second Domain* (2002) (71)
Membrane protein stability can be compromised by detergent interactions with the extramembranous soluble domains (2014) (71)
Misassembled mutant ΔF508 CFTR in the distal secretory pathway alters cellular lipid trafficking (2006) (69)
The role of cystic fibrosis transmembrane conductance regulator phenylalanine 508 side chain in ion channel gating (2006) (68)
Cystic fibrosis-type mutational analysis in the ATP-binding cassette transporter signature of human P-glycoprotein MDR1. (1994) (67)
The cystic fibrosis transmembrane conductance regulator chloride channel. Iodide block and permeation. (1992) (66)
Non‐specific activation of the epithelial sodium channel by the CFTR chloride channel (2001) (66)
F508del CFTR with two altered RXR motifs escapes from ER quality control but its channel activity is thermally sensitive. (2006) (64)
Functional expression and apical localization of the cystic fibrosis transmembrane conductance regulator in MDCK I cells. (1997) (64)
Over‐Expression of the DM‐20 Myelin Proteolipid Causes Central Nervous System Demyelination in Transgenic Mice (1995) (64)
Metallothionein accumulation may account for intracellular copper retention in Menkes' disease. (1982) (63)
Multiple flavonoid-binding sites within multidrug resistance protein MRP1 (2003) (62)
SERCA pump inhibitors do not correct biosynthetic arrest of deltaF508 CFTR in cystic fibrosis. (2006) (60)
Architecture of the cystic fibrosis transmembrane conductance regulator protein and structural changes associated with phosphorylation and nucleotide binding. (2009) (60)
Intermediate Structural States Involved in MRP1-mediated Drug Transport (2003) (59)
Dual Effects of Adp and Adenylylimidodiphosphate on Cftr Channel Kinetics Show Binding to Two Different Nucleotide Binding Sites (1999) (59)
Role of individual R domain phosphorylation sites in CFTR regulation by protein kinase A. (2009) (58)
Study of the expression of myelin proteolipid protein (lipophilin) using a cloned complementary DNA. (1985) (56)
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) (2011) (56)
cAMP- and Ca2+-independent Activation of Cystic Fibrosis Transmembrane Conductance Regulator Channels by Phenylimidazothiazole Drugs* (1996) (55)
Expression and degradation of the cystic fibrosis transmembrane conductance regulator in Saccharomyces cerevisiae. (2001) (53)
Computational studies reveal phosphorylation-dependent changes in the unstructured R domain of CFTR. (2008) (52)
Restoration of NBD1 thermal stability is necessary and sufficient to correct ∆F508 CFTR folding and assembly. (2015) (52)
Diminished Self-Chaperoning Activity of the ΔF508 Mutant of CFTR Results in Protein Misfolding (2008) (52)
ATP Binding to the First Nucleotide Binding Domain of Multidrug Resistance-associated Protein Plays a Regulatory Role at Low Nucleotide Concentration, whereas ATP Hydrolysis at the Second Plays a Dominant Role in ATP-dependent Leukotriene C4 Transport* (2003) (50)
Cystic Fibrosis: Channel, Catalytic, and Folding Properties of the CFTR Protein (1997) (48)
Lectin-induced inhibition of plasma membrane 5'-nucleotidase: sensitivity of purified enzyme. (1977) (48)
Rational coupled dynamics network manipulation rescues disease-relevant mutant cystic fibrosis transmembrane conductance regulator (2014) (48)
Determination of CFTR chloride channel activity and pharmacology using radiotracer flux methods. (2004) (48)
Effects of calcium and lead on potassium permeability of human erythrocyte ghosts. (1971) (48)
Novel Regulation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channel Gating by External Chloride* (2004) (47)
Relationship between nucleotide binding and ion channel gating in cystic fibrosis transmembrane conductance regulator (2009) (47)
Chromosomal location of human P-glycoprotein gene sequences. (1987) (44)
Human myelin DM-20 proteolipid protein deletion defined by cDNA sequence. (1987) (44)
Localization of Sequences within the C-terminal Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Which Impact Maturation and Stability* (2001) (43)
Crystallographic and single-particle analyses of native- and nucleotide-bound forms of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. (2005) (41)
ATP Binding, Not Hydrolysis, at the First Nucleotide-binding Domain of Multidrug Resistance-associated Protein MRP1 Enhances ADP·Vi Trapping at the Second Domain* (2003) (41)
Purification of low molecular weight copper proteins from copper loaded liver. (1975) (40)
The cystic fibrosis gene: isolation and significance. (1990) (39)
The C-terminus of the transmembrane mucin MUC17 binds to the scaffold protein PDZK1 that stably localizes it to the enterocyte apical membrane in the small intestine. (2008) (37)
Induction of expression of the cystic fibrosis transmembrane conductance regulator. (1992) (35)
CHAPTER 29 – THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (ABCC7) (2003) (34)
Stimulation of ATPase Activity of Purified Multidrug Resistance-associated Protein by Nucleoside Diphosphates* (1998) (34)
Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel. (2018) (34)
Protein kinase C mediates down-regulation of cystic fibrosis transmembrane conductance regulator levels in epithelial cells. (1993) (33)
Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA. (2003) (32)
Multidrug resistance protein MRP1 reconstituted into lipid vesicles: secondary structure and nucleotide-induced tertiary structure changes. (2000) (32)
Domain location within the cystic fibrosis transmembrane conductance regulator protein investigated by electron microscopy and gold labelling. (2011) (32)
Mapping of DNA markers linked to the cystic fibrosis locus on the long arm of chromosome 7. (1987) (32)
Binding of [3H]cytochalasin B and [3H]colchicine to isolated liver plasma membranes (1977) (31)
A two‐domain model for the R domain of the cystic fibrosis transmembrane conductance regulator based on sequence similarities (1994) (31)
Functional analysis of the C-terminal boundary of the second nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator and structural implications. (2002) (31)
Disease-associated Mutations in the Extracytoplasmic Loops of Cystic Fibrosis Transmembrane Conductance Regulator Do Not Impede Biosynthetic Processing but Impair Chloride Channel Stability* (2001) (31)
Characterization of polyclonal and monoclonal antibodies to cystic fibrosis transmembrane conductance regulator. (1998) (30)
Equilibrium, kinetic and photoaffinity labeling studies of daunomycin binding to P-glycoprotein-containing membranes of multidrug-resistant Chinese hamster ovary cells. (1989) (29)
Bcr (breakpoint cluster region) protein binds to PDZ-domains of scaffold protein PDZK1 and vesicle coat protein Mint3 (2004) (29)
Collateral sensitivity of multidrug resistant cells to narcotic analgesics is due to effects on the plasma membrane. (1995) (27)
Preparation and utility of a radioiodinated analogue of daunomycin in the study of multidrug resistance. (1989) (27)
The cubicon method for concentrating membrane proteins in the cubic mesophase (2017) (27)
Domain-interface dynamics of CFTR revealed by stabilizing nanobodies (2019) (25)
Bicarbonate permeability of the outwardly rectifying anion channel (1989) (24)
Concanavalin A binding to membranes of the Golgi apparatus and resultant modification of galactosyltransferase activity. (1976) (24)
Differential regulation of single CFTR channels by PP2C, PP2A, and other phosphatases. (1998) (23)
Glycoprotein Membrane Enzymes (1978) (22)
Regulation of the cystic fibrosis transmembrane conductance regulator anion channel by tyrosine phosphorylation (2015) (22)
Cryo-EM visualization of an active high open probability CFTR anion channel (2018) (22)
Fluorescent modified phosphatidylcholine floppase activity of reconstituted multidrug resistance-associated protein MRP1. (2004) (22)
A Stable Human-Cell System Overexpressing Cystic Fibrosis Transmembrane Conductance Regulator Recombinant Protein at the Cell Surface (2015) (22)
Selective permeability barrier to urea in shark rectal gland. (2005) (22)
Nature of the lectin-induced activation of plasma membrane Mg2+ATPase. (1977) (21)
Small copper-binding proteins from normal and copper-loaded liver. (1975) (21)
Mutation analysis in cystic fibrosis. (1990) (20)
Characteristics of nucleotide-converting enzymes at muscle surfaces with special reference to ion sensitivity. (1968) (19)
Antibodies to low molecular weight copper binding protein from liver. (1977) (18)
Nucleotide‐induced conformational changes in the human multidrug resistance protein MRP1 are related to the capacity of chemotherapeutic drugs to accumulate or not in resistant cells (2001) (18)
Thermal stability of purified and reconstituted CFTR in a locked open channel conformation. (2015) (18)
CFTR, a channel with the structure of a transporter (1992) (17)
Fast kinetic analysis of drug transport in multidrug resistant cells using a pulsed quench-flow apparatus. (1990) (16)
Heterologous expression systems for study of cystic fibrosis transmembrane conductance regulator. (1998) (16)
Mg2+ -dependent ATP occlusion at the first nucleotide-binding domain (NBD1) of CFTR does not require the second (NBD2). (2008) (16)
Progress towards cloning the cystic fibrosis gene. (1988) (15)
Observations on serological epidemiology antibodies to the Lansing strain of poliomyelitis virus in sera from Alaskan eskimos. (1950) (15)
The search for the cystic fibrosis gene. (1989) (14)
The binding of asialo-glycoprotein to isolated Golgi apparatus. (1974) (14)
Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations (2017) (14)
Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1. (2018) (13)
Plasma membrane lipids of human diploid fibroblasts from normal individuals and patients with cystic fibrosis. (1979) (13)
Uptake and metabolism of purine nucleosides and nucleotides in isolated frog skeletal muscle. (1977) (13)
Potential sites of CFTR activation by tyrosine kinases (2016) (13)
Calcium-potassium-stimulated net potassium efflux from human erythrocyte ghosts (1975) (12)
Targeted Proteomic Quantitation of the Absolute Expression and Turnover of Cystic Fibrosis Transmembrane Conductance Regulator in the Apical Plasma Membrane (2014) (12)
Induction of alkaline phosphatase in cultured human fibroblasts. Comparison of normal cells and those from patients with cystic fibrosis. (1979) (11)
Erratum: Correctors of dF508 CFTR restore global conformational maturation without thermally stabilizing the mutant protein (FASEB Journal (2013) 27 (536 -545) DOI:10.1096/fj.12-216119) (2014) (11)
alpha-L-Fucosidase is quantitatively reduced in cultured lymphoblasts from patients with cystic fibrosis. (1981) (11)
Ordering of bulk membrane lipid or protein promotes activity of plasma membrane Mg2+ATPase. (1980) (10)
Genetics and epithelial cell dysfunction in cystic fibrosis : proceedings of symposium held in Kimberly, Ontario, Canada, November 12-15, 1986 (1987) (10)
A novel CFTR disease-associated mutation causes addition of an extra N-linked oligosaccharide (2004) (10)
Role of membranes in disease. (1986) (10)
Isolation and characterization of the plasma membranes of cultured lymphoblasts from patients with cystic fibrosis and normal individuals. (1980) (10)
MSP RFLP for X-linked proteolipid protein gene (PLP) identified with either rat or human PLP cDNA clone. (1987) (9)
Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator (2018) (9)
Systematic study of the hydrolysis of 4-methylumbelliferylguanidinobenzoate in plasma from patients with cystic fibrosis and controls. (1982) (8)
Collateral Sensitivity of Multidrug Resistant Cells (1991) (8)
Transmembrane helical interactions in the CFTR channel pore (2017) (8)
CFTR degradation depends on the lectins Htm 1 p / EDEM and the Cdc 48 protein complex in yeast (2004) (8)
Chemical and Biological Folding Contribute to Temperature-Sensitive D F 508 CFTR Trafficking (2008) (8)
A Secretory Cl Channel from Epithelial Cells Studied in Heterologous Expression Systems (1994) (8)
Membrane Lipids of Multidrug-Resistant Cells: Chemical Composition and Physical State (1991) (8)
Testing for Bias in the Climate Record (7)
Culture of sweat gland epithelial cells from normal individuals and patients with cystic fibrosis (1985) (6)
Therapeutic strategies for treatment of CF based on knowledge of CFTR (1999) (6)
Incorporation in vivo of [32P]orthophosphate and [Me-3H]choline into rough microsomal, Golgi, and plasma membranes of rat liver. (1977) (5)
Influence of ethacrynic acid on muscle surface enzymes and of ethacrynic acid and ouabain on Na, K, and H 2 O in frog muscle. (1972) (5)
cAMP-binding proteins in epithelial cells cultured from human sweat glands. (1990) (5)
Erratum: ATPase activity of purified multidrug resistance-associated protein (Journal of Biological Chemistry (1997) 272 (30962-30968)) (1998) (5)
Plasma Membrane Mg2+ATPase Activity is Inversely Related to Lipid Fluidity (1980) (5)
Etiology of CF: Knowns and unknowns (1999) (5)
Isolation of plasma membranes from human skin fibroblasts (1977) (4)
Domain-interface dynamics of CFTR revealed by stabilizing nanobodies (2019) (4)
Structure of the cystic fibrosis transmembrane conductance regulator in the inward-facing conformation revealed by single particle electron microscopy (2015) (4)
Development and characterization of synthetic antibodies binding to the cystic fibrosis conductance regulator (2016) (3)
Cyclic nucleotides and cystic fibrosis. (1980) (3)
Selection and characterization of verapamil-resistant multidrug resistant cells. (1995) (3)
Low molecular weight copper-binding proteins in cultured human cells. (1979) (3)
R-Domain Phosphorylation by Protein Kinase A Stimulates Dissociation of Unhydrolyzed ATP from the First Nucleotide-Binding Site of the Cystic Fibrosis Transmembrane Conductance Regulator. (2018) (3)
Cryo-EM visualization of an active high open probability CFTR ion channel (2018) (3)
A gene regulating the time dependence of α-l-fucosidase concentration is closely linked with the structural gene in man (2004) (3)
Search for proteins with similarity to the CFTR R domain using an optimized RDBMS solution, mBioSQL (2006) (2)
Quantitation of Mdr1 Transcript by PCR a Tool for Monitoring Drug Resistance in Cancer Chemotherapy (1991) (2)
Insulin modulation of antibody-dependent cytotoxicity and the detection of antireceptor antibodies. (1982) (2)
Genetically Defined Myelin Disorders (1992) (2)
Opiates inhibit ion conductances elicited by cell swelling and cAMP in cultured cells. (1995) (2)
Identification of sequences of chromosome 7 that are expressed in sweat gland epithelial cells (1990) (1)
Binding of [3H]ctyochalasin B and [3H]colchicine to isolated liver plasma membranes. (1977) (1)
Isolation of plasma membrane vesicles from colchicine resistant permeability mutants of Chinese hamster ovary cells (1978) (1)
SERCA Pump Inhibitors Do Not Correct Biosynthetic Arrest of (cid:1) F508 CFTR in Cystic Fibrosis (2006) (1)
Erratum to: A Stable Human-Cell System Overexpressing Cystic Fibrosis Transmembrane Conductance Regulator Recombinant Protein at the Cell Surface (2015) (1)
Cystic fibrosis : a trilogy of biochemistry, physiology, and therapy (2013) (1)
mRNA Phenotyping by polymerase chain reaction: a rapid and sensitive protocol for the quantitation of MDR1 contents in cancer cells (1990) (0)
healthy human adults The effect of exercise on nasal uptake of ozone in (2015) (0)
Cystic fibrosis: depressed alpha-fucosidase activity in cultured lymphoblasts. (1980) (0)
Early life of cystic fibrosis transmembrane conductance regulator (CFTR) in the cell (2001) (0)
Erratum: (Journal of Cell Biology (October 11, 2004) 167:1 (65-74)) (2004) (0)
In£uence of phosphorylation by protein kinase A on CFTR at the cell surface and endoplasmic reticulum (1999) (0)
A Robust High-Throughput Assay for Thermodynamic Correctors of the Predominant Molecular Defect Causing Cystic Fibrosis (2014) (0)
Forefronts in Nephrology: The molecular basis of renal cystic disease: II. Abnormal Transport By Epithelial Cells: CFTR: Cloning, mutations and functions (1995) (0)
Phenylalanine 508 forms an intra‐domain contact crucial to CFTR folding and dynamics (2009) (0)
[From the gene to the physiopathology: the functions of CFTR protein]. (1996) (0)
Thermodynamic correction of F 508 del-CFTR 1 Ligand binding to a remote site thermodynamically corrects the F 508 del mutation in the human cystic fibrosis transmembrane conductance regulator (2018) (0)
The conjugation of ligands to immobilized proteins in an organic solvent (1996) (0)
Insulin resistance in total lipodystrophy: Demonstration of an insulin receptor defect (1977) (0)
CFTR: Understanding the cause and influencing the outcome of a major genetic disease (2011) (0)
Correction (2004) (0)
human NBD1 of CFTR in complex with nanobodies T2a and T4 (2019) (0)
human NBD1 of CFTR in complex with nanobodies D12 and G3a (2019) (0)
[22]4 Gas Pipeline Networks. The Institutional, Legal and Economic Framework for Pipeline Networks in North America (1994) (0)
Copper entry into and exit from cultured human cells (1985) (0)
PROGRESS TOWARDS CLONING OF THE CYSTIC FIBROSIS GENE — IDENTIFICATION OF NEW DNA MARKERS IN THE 7Q31 REGION (1987) (0)
human NBD1 of CFTR in complex with nanobody T27 (2019) (0)
Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with 5-methyl-UTP (2018) (0)
Purification of a plasma membrane glycoprotein apparently unique to colchicine resistant permeability mutants of Chinese hamster ovary cells (1979) (0)
Human NBD1 of CFTR in complex with nanobodies D12 and T8 (2019) (0)
Toward CFTR Structural Dynamics During Ion Channel Gating (2009) (0)
Symposia session summaries (2005) (0)
Western Blotting : A Guide to Current Methods Introductions (0)
Human NBD1 of CFTR in complex with nanobodies D12 and T4 (2019) (0)
Plasma membranes of drug resistant permeability mutants of chinese hamster ovary cells (1980) (0)
Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966. (2012) (0)
Isolation of cDNA clones for myelin proteolipid protein (lipophilin) (1985) (0)

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