John S. Parkinson
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American biologist
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John S. Parkinsonbiology Degrees
Biology
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Genetics
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Molecular Biology
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Biology
John S. Parkinson's Degrees
- Bachelors Biology University of California, Berkeley
- Masters Genetics Stanford University
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Why Is John S. Parkinson Influential?
(Suggest an Edit or Addition)According to Wikipedia, John Stansfield "Sandy" Parkinson is an American biologist, currently a Distinguished Professor at University of Utah. He was the chairman of the Department of Biology at University of Utah. Research Parkinson studies bacterial chemotaxis, particularly the chemotactic behavior of E. coli to elucidate the molecular mechanisms that cells use to detect and process information about their chemical environment. Parkinson began mutational analysis of E. coli chemotaxis as a postdoctoral student with Julius Adler in 1970. As an independent investigator, Parkinson became the primary source of mutant strains, generously making available his vast strain collection and his knowledge and thus enhancing the collective progress of the field.
John S. Parkinson's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Communication modules in bacterial signaling proteins. (1992) (1532)
- Signal transduction schemes of bacteria (1993) (767)
- Bacterial chemoreceptors: high-performance signaling in networked arrays. (2008) (592)
- Signal Transduction via the Multi-Step Phosphorelay: Not Necessarily a Road Less Traveled (1996) (418)
- Isolation and behavior of Escherichia coli deletion mutants lacking chemotaxis functions (1982) (387)
- Collaborative signaling by mixed chemoreceptor teams in Escherichia coli (2002) (326)
- Complementation analysis and deletion mapping of Escherichia coli mutants defective in chemotaxis (1978) (308)
- Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update. (2015) (298)
- A signal transducer for aerotaxis in Escherichia coli (1997) (297)
- Deletion mutants of bacteriophage lambda. I. Isolation and initial characterization. (1971) (256)
- Bacterial motility: membrane topology of the Escherichia coli MotB protein. (1988) (220)
- A model of excitation and adaptation in bacterial chemotaxis. (1997) (208)
- Crosslinking snapshots of bacterial chemoreceptor squads (2004) (198)
- cheA, cheB, and cheC genes of Escherichia coli and their role in chemotaxis (1976) (193)
- Signaling mechanisms of HAMP domains in chemoreceptors and sensor kinases. (2010) (172)
- Genetics of the left arm of the chromosome of bacteriophage lambda. (1968) (166)
- Collaborative signaling by bacterial chemoreceptors. (2005) (164)
- Coupling the phosphotransferase system and the methyl-accepting chemotaxis protein-dependent chemotaxis signaling pathways of Escherichia coli. (1995) (162)
- Transmitter and receiver modules in bacterial signaling proteins. (1988) (160)
- Overlapping genes at the cheA locus of Escherichia coli. (1980) (147)
- Genetic evidence for interaction between the CheW and Tsr proteins during chemoreceptor signaling by Escherichia coli (1991) (141)
- Constitutively signaling fragments of Tsr, the Escherichia coli serine chemoreceptor (1994) (139)
- Deletion mutants of bacteriophage lambda: III. Physical structure of attφ (1971) (136)
- Interactions between chemotaxis genes and flagellar genes in Escherichia coli (1983) (136)
- NMR structure of activated CheY. (2000) (134)
- Mutational analyses of HAMP helices suggest a dynamic bundle model of input–output signalling in chemoreceptors (2009) (134)
- Domain organization and flavin adenine dinucleotide-binding determinants in the aerotaxis signal transducer Aer of Escherichia coli. (2000) (131)
- New unified nomenclature for the flagellar genes of Escherichia coli and Salmonella typhimurium. (1988) (127)
- Role of CheW protein in coupling membrane receptors to the intracellular signaling system of bacterial chemotaxis. (1989) (127)
- Insights into the organization and dynamics of bacterial chemoreceptor clusters through in vivo crosslinking studies (2005) (126)
- Transmembrane signaling by bacterial chemoreceptors: E. coli transducers with locked signal output (1988) (118)
- Genetics and sequence analysis of the pcnB locus, an Escherichia coli gene involved in plasmid copy number control (1989) (114)
- Liberation of an interaction domain from the phosphotransfer region of CheA, a signaling kinase of Escherichia coli. (1994) (107)
- Biphasic control logic of HAMP domain signalling in the Escherichia coli serine chemoreceptor (2011) (90)
- Methylation-Independent Aerotaxis Mediated by the Escherichia coli Aer Protein (2004) (88)
- Behavioral genetics in bacteria. (1977) (79)
- Tandem translation starts in the cheA locus of Escherichia coli (1991) (79)
- Genetic Approaches for Signaling Pathways and Proteins (1995) (73)
- Functional homology of chemotaxis genes in Escherichia coli and Salmonella typhimurium (1979) (73)
- Sensory adaptation mutants of E. coli (1978) (72)
- Mutational Analysis of the Connector Segment in the HAMP Domain of Tsr, the Escherichia coli Serine Chemoreceptor (2008) (70)
- The source of high signal cooperativity in bacterial chemosensory arrays (2016) (67)
- Requirement of the cheB function for sensory adaptation in Escherichia coli (1983) (66)
- Signaling Interactions between the Aerotaxis Transducer Aer and Heterologous Chemoreceptors in Escherichia coli (2006) (64)
- Aspartate taxis mutants of the Escherichia coli tar chemoreceptor (1988) (61)
- The mobility of two kinase domains in the Escherichia coli chemoreceptor array varies with signalling state (2013) (61)
- Methylation segments are not required for chemotactic signalling by cytoplasmic fragments of Tsr, the methyl‐accepting serine chemoreceptor of Escherichia coli (1996) (60)
- Protein phosphorylation in bacterial chemotaxis (1988) (58)
- Posttranslational processing of methyl-accepting chemotaxis proteins in Escherichia coli. (1981) (56)
- The smaller of two overlapping cheA gene products is not essential for chemotaxis in Escherichia coli (1995) (52)
- Genetics of methyl-accepting chemotaxis proteins in Escherichia coli: organization of the tar region (1983) (52)
- Deletion mutants of bacteriophage lambda. II. Genetic properties of att-defective mutants. (1971) (50)
- Loss- and Gain-of-Function Mutations in the F1-HAMP Region of the Escherichia coli Aerotaxis Transducer Aer (2006) (49)
- Interaction of the cheC and cheZ gene products is required for chemotactic behavior in Escherichia coli. (1979) (48)
- Phenol Sensing by Escherichia coli Chemoreceptors: a Nonclassical Mechanism (2011) (47)
- Genetics of methyl-accepting chemotaxis proteins in Escherichia coli: null phenotypes of the tar and tap genes (1985) (46)
- Conformational suppression of inter-receptor signaling defects. (2006) (45)
- Bacterial Chemotaxis: a New Player in Response Regulator Dephosphorylation (2003) (45)
- Mutational Analysis of the Control Cable That Mediates Transmembrane Signaling in the Escherichia coli Serine Chemoreceptor (2011) (45)
- Disruption of chemoreceptor signalling arrays by high levels of CheW, the receptor–kinase coupling protein (2010) (44)
- A phenylalanine rotameric switch for signal-state control in bacterial chemoreceptors (2013) (42)
- A mutant hook-associated protein (HAP3) facilitates torsionally induced transformations of the flagellar filament of Escherichia coli. (1994) (39)
- Chemotactic Signaling by an Escherichia coli CheA Mutant That Lacks the Binding Domain for Phosphoacceptor Partners (2004) (39)
- Chemotactic signaling by the P1 phosphorylation domain liberated from the CheA histidine kinase of Escherichia coli (1996) (36)
- Mutational Analysis of the Chemoreceptor-Coupling Domain of the Escherichia coli Chemotaxis Signaling Kinase CheA (2006) (36)
- Functional suppression of HAMP domain signaling defects in the E. coli serine chemoreceptor. (2014) (34)
- Complete structure of the chemosensory array core signalling unit in an E. coli minicell strain (2020) (33)
- Different Signaling Roles of Two Conserved Residues in the Cytoplasmic Hairpin Tip of Tsr, the Escherichia coli Serine Chemoreceptor (2008) (33)
- Novel Mutations Affecting a Signaling Component for Chemotaxis of Escherichia coli (1980) (32)
- A "bucket of light" for viewing bacterial colonies in soft agar. (2007) (32)
- Networked Chemoreceptors Benefit Bacterial Chemotaxis Performance (2016) (31)
- Data processing by the chemotaxis machinery of Escherichia coli (1974) (30)
- Differential Activation of Escherichia coli Chemoreceptors by Blue-Light Stimuli (2006) (30)
- Does E. coli have a nose? (1993) (30)
- HAMP domain structural determinants for signalling and sensory adaptation in Tsr, the Escherichia coli serine chemoreceptor (2014) (30)
- Genetic analysis of the bacterial flagellum. (1991) (30)
- Structure and dynamics of the E. coli chemotaxis core signaling complex by cryo-electron tomography and molecular simulations (2020) (29)
- In Situ Conformational Changes of the Escherichia coli Serine Chemoreceptor in Different Signaling States (2019) (28)
- Cysteine-Scanning Analysis of the Chemoreceptor-Coupling Domain of the Escherichia coli Chemotaxis Signaling Kinase CheA (2006) (28)
- A fragment liberated from the Escherichia coli CheA kinase that blocks stimulatory, but not inhibitory, chemoreceptor signaling (1997) (27)
- Bacterial Chemotaxis: Molecular Genetics of Sensory Transduction and Chemotactic Gene Expression (1983) (24)
- Structure-function studies of bacterial chemosensors. (1988) (24)
- An Unorthodox Sensory Adaptation Site in the Escherichia coli Serine Chemoreceptor (2013) (24)
- Genetics of methyl-accepting chemotaxis proteins in Escherichia coli: cheD mutations affect the structure and function of the Tsr transducer (1985) (22)
- Signalling‐dependent interactions between the kinase‐coupling protein CheW and chemoreceptors in living cells (2014) (22)
- A physical map of the left arm of the lambda chromosome. (1971) (21)
- Mutational Analysis of N381, a Key Trimer Contact Residue in Tsr, the Escherichia coli Serine Chemoreceptor (2011) (21)
- Signal Transduction via the Minireview Multi-Step Phosphorelay : Not Necessarily a Road Less Traveled (1996) (21)
- In vivo crosslinking methods for analyzing the assembly and architecture of chemoreceptor arrays. (2007) (20)
- Evidence for a Helix-Clutch Mechanism of Transmembrane Signaling in a Bacterial Chemoreceptor. (2016) (19)
- A Trigger Residue for Transmembrane Signaling in the Escherichia coli Serine Chemoreceptor (2015) (18)
- Chemotaxis in Escherichia coli: construction and properties of lambda tsr transducing phage (1987) (17)
- Genetics of chemotactic behavior in bacteria (1975) (16)
- Under Elevated c-di-GMP in Escherichia coli, YcgR Alters Flagellar Motor Bias and Speed Sequentially, with Additional Negative Control of the Flagellar Regulon via the Adaptor Protein RssB (2019) (15)
- Mutational Analysis of the P1 Phosphorylation Domain in Escherichia coli CheA, the Signaling Kinase for Chemotaxis (2013) (15)
- Cross-linking evidence for motional constraints within chemoreceptor trimers of dimers. (2011) (15)
- Signaling Consequences of Structural Lesions that Alter the Stability of Chemoreceptor Trimers of Dimers. (2017) (15)
- Noncritical Signaling Role of a Kinase-Receptor Interaction Surface in the Escherichia coli Chemosensory Core Complex. (2018) (14)
- Constitutively Signaling Fragments of Tsr, the E. coli Serine Chemoreceptor (1994) (12)
- cheA,cheB,andcheCGenesofEscherichia coli andTheir RoleinChemotaxis (1976) (12)
- Hybrid Escherichia coli sensory transducers with altered stimulus detection and signaling properties (1987) (9)
- Classic Spotlight: the Discovery of Bacterial Transduction (2016) (9)
- Identification of a Kinase-Active CheA Conformation in Escherichia coli Chemoreceptor Signaling Complexes (2019) (9)
- A zipped-helix cap potentiates HAMP domain control of chemoreceptor signaling (2018) (9)
- Signaling Mechanisms of HAMP Domains in Chemoreceptors (2010) (8)
- GENETICS OF TRANSMEMBRANE SIGNALING PROTEINS IN E. COLI (1983) (8)
- Signal amplification in bacterial chemotaxis through receptor teamwork (2004) (7)
- Hexameric rings of the scaffolding protein CheW enhance response sensitivity and cooperativity in Escherichia coli chemoreceptor arrays (2022) (7)
- Doing behavioral genetics with bacteria. (1987) (6)
- Ancient chemoreceptors retain their flexibility (2007) (5)
- New unified nomenclature for the flagellar genes of Escherichia coli and Salmonella typhimurium (1988) (5)
- Phenotypic suppression methods for analyzing intra- and inter-molecular signaling interactions of chemoreceptors. (2007) (5)
- Chemotactic Signaling by Single-Chain Chemoreceptors (2015) (4)
- Conformational shifts in a chemoreceptor helical hairpin control kinase signaling in Escherichia coli (2019) (4)
- Genetics of bacterial chemo taxis (1981) (4)
- Interactions Between Chemotaxis Genes and Flagellar Genes (1983) (4)
- Monitoring Two-Component Sensor Kinases with a Chemotaxis Signal Readout. (2018) (3)
- Chemotaxis in Escherichia coli: Construction and Properties of Xtsr (1987) (3)
- Deletion mutants of bacteriophage lambda. 3. Physical structure of att-phi. (1971) (3)
- Structural signatures of Escherichia coli chemoreceptor signaling states revealed by cellular crosslinking (2022) (3)
- A Macintosh program for drawing circular plasmid maps (1989) (3)
- Classic Spotlight: Dawn of the Molecular Era of Bacterial Chemotaxis (2016) (2)
- Paradoxical enhancement of chemoreceptor detection sensitivity by a sensory adaptation enzyme (2017) (2)
- Complete structure of the core signalling unit of the E. coli chemosensory array in an optimised minicell strain (2019) (2)
- Bacterial chemotaxis and methionine (1976) (2)
- All-Codon Mutagenesis for Structure-Function Studies of Chemotaxis Signaling Proteins. (2018) (1)
- Near-critical tuning of cooperativity revealed by spontaneous switching in a protein signalling array (2023) (1)
- Novel Mutations Affecting a Signaling Component for (2008) (0)
- Transmitter and receiver modules in bacterial signaling proteins ( signal transduction / regulation / protein structure / evolution / chemotaxis ) (0)
- SOLUTION STRUCTURE OF BEF3-ACTIVATED CHEY FROM ESCHERICHIA COLI (2000) (0)
- Mutational Analysis of the Control Cable That Mediates Transmembrane Signaling in the <named-content content-type='genus-species' xlink:type='simple'>Escherichia coli</named-content> Serine Chemoreceptor (2011) (0)
- HAMP: The CPU Domain of Bacterial Chemoreceptors (2015) (0)
- in E. coli CheA, the Signaling Kinase for Chemotaxis (2013) (0)
- Stevens-Johnson syndrome linked to tramadol use and ultraviolet radiation (2021) (0)
- Organization and function of the phage Lambda chromosome (1970) (0)
- Classic Spotlight: Selected Highlights from the First 100 Years of the Journal of Bacteriology (2017) (0)
- Structure of the Native Chemotaxis Core Signalling Unit from E-gene lysed E. coli cells (2023) (0)
- Classic Spotlight: Look, Max—No Math Required! (2016) (0)
- Signaling Mutants of the P1 Phosphorylation Domain in the CheA Histidine Kinase of E. Coli. (2000) (0)
- The Chemoreceptor Sensory Adaptation System Produces Coordinated Reversals of the Flagellar Motors on an Escherichia coli Cell (2022) (0)
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