John R. Yarnold
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John R. Yarnold's Degrees
- PhD Radiation Oncology University of Oxford
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(Suggest an Edit or Addition)John R. Yarnold's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial (2008) (1096)
- The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials. (2013) (1028)
- The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial (2008) (945)
- Comparison of radiation side-effects of conformal and conventional radiotherapy in prostate cancer: a randomised trial (1999) (761)
- Effect of radiotherapy fraction size on tumour control in patients with early-stage breast cancer after local tumour excision: long-term results of a randomised trial. (2006) (534)
- Pathogenetic mechanisms in radiation fibrosis. (2010) (480)
- Randomised trial of standard 2D radiotherapy (RT) versus intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. (2007) (472)
- Fractionation sensitivity and dose response of late adverse effects in the breast after radiotherapy for early breast cancer: long-term results of a randomised trial. (2005) (472)
- Prospective randomised trial of single and multifraction radiotherapy schedules in the treatment of painful bony metastases. (1986) (447)
- aTTom: Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years in 6,953 women with early breast cancer. (2013) (426)
- Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial (2020) (406)
- Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial (2020) (406)
- 8 Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: randomised comparison with a multifraction schedule over 12 months of patient follow-upOn behalf of the Bone Pain Trial Working Party (1999) (368)
- Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial (2017) (359)
- ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer. (2015) (350)
- Prophylactic cranial irradiation is indicated following complete response to induction therapy in small cell lung cancer: Results of a multicentre randomised trial (1997) (328)
- The influence of breast size on late radiation effects and association with radiotherapy dose inhomogeneity. (1994) (246)
- A prospective randomised trial of 4 Gy or 8 Gy single doses in the treatment of metastatic bone pain. (1992) (236)
- First results of the randomised UK FAST Trial of radiotherapy hypofractionation for treatment of early breast cancer (CRUKE/04/015). (2011) (216)
- Comparison of patient-reported breast, arm, and shoulder symptoms and body image after radiotherapy for early breast cancer: 5-year follow-up in the randomised Standardisation of Breast Radiotherapy (START) trials. (2010) (208)
- Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials (2019) (197)
- Cosmetic and functional outcomes of breast conserving treatment for early stage breast cancer. 1. Comparison of patients' ratings, observers' ratings, and objective assessments. (1992) (195)
- ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer, version 1.1. (2016) (188)
- Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trial (2009) (180)
- Prediction of normal-tissue tolerance to radiotherapy from in-vitro cellular radiation sensitivity (1992) (165)
- The UK HeartSpare Study: randomised evaluation of voluntary deep-inspiratory breath-hold in women undergoing breast radiotherapy. (2013) (159)
- Prone versus supine positioning for whole and partial-breast radiotherapy: a comparison of non-target tissue dosimetry. (2010) (156)
- Carboplatin: a very active new cisplatin analog in the treatment of small cell lung cancer. (1985) (155)
- Hypofractionated whole-breast radiotherapy for women with early breast cancer: myths and realities. (2011) (151)
- Acute skin toxicity associated with a 1-week schedule of whole breast radiotherapy compared with a standard 3-week regimen delivered in the UK FAST-Forward Trial (2016) (144)
- TGFB1 polymorphisms are associated with risk of late normal tissue complications in the breast after radiotherapy for early breast cancer. (2005) (143)
- Cosmetic and functional outcomes of breast conserving treatment for early stage breast cancer. 2. Relationship with psychosocial functioning. (1992) (140)
- Early and locally advanced breast cancer: diagnosis and treatment National Institute for Health and Clinical Excellence guideline 2009. (2009) (138)
- A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity. (2014) (135)
- Guidelines for time-to-event end point definitions in breast cancer trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials)†. (2015) (135)
- Cellular radiosensitivity and complication risk after curative radiotherapy. (2000) (132)
- Local relapse rates are falling after breast conserving surgery and systemic therapy for early breast cancer: can radiotherapy ever be safely withheld? (2009) (132)
- The delivery of intensity modulated radiotherapy to the breast using multiple static fields. (2000) (127)
- Detection of defects in myocardial perfusion imaging in patients with early breast cancer treated with radiotherapy. (2002) (126)
- The relationship between cellular radiation sensitivity and tissue response may provide the basis for individualising radiotherapy schedules (1994) (108)
- Ten-Year Results of FAST: A Randomized Controlled Trial of 5-Fraction Whole-Breast Radiotherapy for Early Breast Cancer (2020) (108)
- Correlation of breast dose heterogeneity with breast size using 3D CT planning and dose-volume histograms (1995) (107)
- Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer. (2004) (98)
- Carboplatin (Paraplatin; JM8) and etoposide (VP-16) as first-line combination therapy for small-cell lung cancer. (1987) (96)
- Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients. (2016) (92)
- Postmastectomy radiotherapy: questions for the twenty-first century. (1998) (89)
- Radiation fibrosis--current clinical and therapeutic perspectives. (2012) (89)
- Cellular radiosensitivity and DNA damage in primary human fibroblasts. (1994) (88)
- Ovarian ablation or suppression in premenopausal early breast cancer: results from the international adjuvant breast cancer ovarian ablation or suppression randomized trial. (2007) (85)
- Design of compensators for breast radiotherapy using electronic portal imaging. (1995) (85)
- Non-randomised phase II trial of hyperbaric oxygen therapy in patients with chronic arm lymphoedema and tissue fibrosis after radiotherapy for early breast cancer. (2004) (84)
- Evaluation of compensation in breast radiotherapy: a planning study using multiple static fields. (2000) (84)
- Double-blind randomized phase II study of hyperbaric oxygen in patients with radiation-induced brachial plexopathy. (2001) (83)
- A randomised trial of supine versus prone breast radiotherapy (SuPr study): comparing set-up errors and respiratory motion. (2011) (82)
- Accelerated partial breast irradiation trials: diversity in rationale and design. (2009) (74)
- Establishment of a Radiogenomics Consortium. (2010) (74)
- Dose-position and dose-volume histogram analysis of standard wedged and intensity modulated treatments in breast radiotherapy. (2002) (73)
- Low dose single fraction radiotherapy in the treatment of metastatic bone pain: a pilot study. (1988) (72)
- Large breast size as a risk factor for late adverse effects of breast radiotherapy: is residual dose inhomogeneity, despite 3D treatment planning and delivery, the main explanation? (2011) (72)
- The IMPORT trials are launched (September 2006). (2006) (70)
- Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity. (2012) (69)
- The UK HeartSpare Study (Stage IB): randomised comparison of a voluntary breath-hold technique and prone radiotherapy after breast conserving surgery. (2015) (68)
- Quality assurance in conservative treatment of early breast cancer. Report on a consensus meeting of the EORTC Radiotherapy and Breast Cancer Cooperative Groups and the EUSOMA (European Society of Mastology). (1991) (68)
- Reports of unexpected late side effects of accelerated partial breast irradiation--radiobiological considerations. (2010) (67)
- Second cancer incidence risk estimates using BEIR VII models for standard and complex external beam radiotherapy for early breast cancer. (2012) (65)
- Late Toxicity Is Not Increased in BRCA1/BRCA2 Mutation Carriers Undergoing Breast Radiotherapy in the United Kingdom (2006) (65)
- Carboplatin, etoposide, and ifosfamide as intensive chemotherapy for small-cell lung cancer. (1990) (62)
- Clinical impact of IMPORT HIGH trial (CRUK/06/003) on breast radiotherapy practices in the United Kingdom. (2015) (61)
- Target volume definition for external beam partial breast radiotherapy: clinical, pathological and technical studies informing current approaches. (2010) (61)
- Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy. (2011) (61)
- XRCC1 Polymorphism Associated With Late Toxicity After Radiation Therapy in Breast Cancer Patients. (2015) (60)
- Hyperbaric oxygen for patients with chronic bowel dysfunction after pelvic radiotherapy (HOT2): a randomised, double-blind, sham-controlled phase 3 trial (2016) (60)
- Late normal tissue effects in the arm and shoulder following lymphatic radiotherapy: Results from the UK START (Standardisation of Breast Radiotherapy) trials (2017) (59)
- Morbidity of cranial relapse in small cell lung cancer and the impact of radiation therapy. (1986) (59)
- Dosimetric evaluation of compensation in radiotherapy of the breast: MLC intensity modulation and physical compensators. (1997) (57)
- Practical implementation of compensators in breast radiotherapy. (1998) (57)
- Tumor bed delineation for partial breast and breast boost radiotherapy planned in the prone position: what does MRI add to X-ray CT localization of titanium clips placed in the excision cavity wall? (2009) (55)
- Phase II study of vitamin E and pentoxifylline in patients with late side effects of pelvic radiotherapy. (2005) (51)
- Selective avoidance of lymphatic radiotherapy in the conservative management of early breast cancer. (1992) (49)
- Improved dose homogeneity in the breast using tissue compensators. (1991) (48)
- The influence of breast size on late radiation effects and association with radiotherapy dose inhomogeneity (1995) (48)
- Bone metastasis consensus statement. (1992) (47)
- Molecular aspects of cellular responses to radiotherapy. (1997) (47)
- Double-blind, placebo-controlled, randomised phase II trial of IH636 grape seed proanthocyanidin extract (GSPE) in patients with radiation-induced breast induration. (2006) (47)
- Correlation of in vitro lymphocyte radiosensitivity and gene expression with late normal tissue reactions following curative radiotherapy for breast cancer. (2012) (46)
- Characterization of target volume changes during breast radiotherapy using implanted fiducial markers and portal imaging. (2009) (46)
- FAST Phase III RCT of Radiotherapy Hypofractionation for Treatment of Early Breast Cancer: 10-Year Results (CRUKE/04/015) (2018) (46)
- Invited review: tangential breast irradiation--rationale and methods for improving dosimetry. (1994) (46)
- Weight gain after primary surgery for breast cancer - effect of tamoxifen (2005) (46)
- Randomised phase II trial of hyperbaric oxygen therapy in patients with chronic arm lymphoedema after radiotherapy for cancer. (2010) (45)
- Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy (2014) (45)
- Ipsilateral breast tumor relapse: local recurrence versus new primary tumor and the effect of whole-breast radiotherapy on the rate of new primaries. (2011) (43)
- Correlation of breast dose heterogeneity with breast size using 3D CT planning and dose-volume histograms. (1995) (43)
- An investigation into methods of IMRT planning applied to breast radiotherapy. (2008) (42)
- Patient-Reported Outcomes Over 5 Years After Whole- or Partial-Breast Radiotherapy: Longitudinal Analysis of the IMPORT LOW (CRUK/06/003) Phase III Randomized Controlled Trial (2018) (42)
- Clinical dosimetry for radiotherapy to the breast based on imaging with the prototype Royal Marsden Hospital CT simulator. (1987) (42)
- Normal tissue complication probability (NTCP) parameters for breast fibrosis: pooled results from two randomised trials. (2013) (41)
- Radiotherapy for bone metastases. (2001) (41)
- The UK HeartSpare Study (Stage II): Multicentre Evaluation of a Voluntary Breath-hold Technique in Patients Receiving Breast Radiotherapy. (2017) (41)
- Prospective evaluation of a watch policy in patients with inoperable non-small cell lung cancer. (1986) (41)
- Genome‐wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c‐Kit, CD117) and oestrogen receptor‐α (ERα) in response to therapeutic radiation (2009) (37)
- Evaluation of implanted gold seeds for breast radiotherapy planning and on treatment verification: a feasibility study on behalf of the IMPORT trialists. (2011) (37)
- The cost-effectiveness of adjuvant chemotherapy for early breast cancer: A comparison of no chemotherapy and first, second, and third generation regimens for patients with differing prognoses. (2011) (37)
- Increased collagen production in fibroblasts cultured from irradiated skin and effect of TGF β1– clinical study (2000) (37)
- Variation in the manganese superoxide dismutase gene (SOD2) is not a major cause of radiotherapy complications in breast cancer patients. (2002) (36)
- Guidelines for time-to-event end point definitions in breast cancer trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials). (2015) (35)
- Hypofractionated radiotherapy for breast cancer. (2010) (35)
- Radiotherapy for breast cancer, the TARGIT-A trial (2014) (34)
- Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer. (1987) (34)
- Estimating the volume of lung irradiated during tangential breast irradiation using the central lung distance. (1995) (34)
- Quality assurance in daily treatment procedure: patient movement during tangential fields treatment. (1991) (33)
- The relationship between cellular radiation sensitivity and tissue response may provide the basis for individualising radiotherapy schedules. (1995) (33)
- Lymphatic relapse in women with early breast cancer: a difficult management problem. (1999) (33)
- DNA double-strand break repair and induction of apoptosis in ex vivo irradiated blood lymphocytes in relation to late normal tissue reactions following breast radiotherapy (2014) (32)
- Comparison between pulsed-field gel electrophoresis and the comet assay as predictive assays for radiosensitivity in fibroblasts. (1998) (32)
- Acute Chemotherapy–Related Toxicity Is Not Increased in BRCA1 and BRCA2 Mutation Carriers Treated for Breast Cancer in the United Kingdom (2006) (31)
- Planning with intensity-modulated radiotherapy and tomotherapy to modulate dose across breast to reflect recurrence risk (IMPORT High trial). (2011) (31)
- Ductal Carcinoma in Situ (DCIS) of the breast (2012) (31)
- Conducting radiogenomic research--do not forget careful consideration of the clinical data. (2012) (31)
- Radiobiology of breast cancer. (2006) (31)
- Non-surgical Management of Early Breast Cancer in the United Kingdom: Radiotherapy Fractionation Practices (1995) (30)
- Prolongation of overall treatment time as a cause of treatment failure in early breast cancer: An analysis of the UK START (Standardisation of Breast Radiotherapy) trials of radiotherapy fractionation. (2016) (30)
- Breast radiotherapy: less is more? (2013) (29)
- Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride. (2007) (29)
- Acute toxicity and 2-year adverse effects of 30 Gy in five fractions over 15 days to whole breast after local excision of early breast cancer. (2008) (28)
- Inter-individual and inter-cell type variation in residual DNA damage after in vivo irradiation of human skin. (2011) (28)
- How does knowledge of three-dimensional excision margins following breast conservation surgery impact upon clinical target volume definition for partial-breast radiotherapy? (2010) (28)
- Changes in radiotherapy fractionation—breast cancer (2018) (28)
- Homologous recombination mediates cellular resistance and fraction size sensitivity to radiation therapy. (2013) (27)
- Titanium clip placement to allow accurate tumour bed localisation following breast conserving surgery – audit on behalf of the IMPORT Trial Management Group (2008) (27)
- Do Patient-reported Outcome Measures Agree with Clinical and Photographic Assessments of Normal Tissue Effects after Breast Radiotherapy? The Experience of the Standardisation of Breast Radiotherapy (START) Trials in Early Breast Cancer. (2016) (26)
- The Relationship Between Homologous Recombination Repair and the Sensitivity of Human Epidermis to the Size of Daily Doses Over a 5-Week Course of Breast Radiotherapy (2012) (25)
- Evaluation of a method for grading late photographic change in breast appearance after radiotherapy for early breast cancer. (2008) (25)
- The surgical treatment of radiation injuries after radiotherapy for uterine carcinoma (1981) (25)
- Selective avoidance of lymphatic irradiation in the conservative management of breast cancer. (1984) (23)
- Benefits expected from simple conformal radiotherapy in the treatment of pelvic tumours. (1988) (22)
- Shorter fractionation schedules in breast cancer radiotherapy: clinical and economic implications. (2009) (22)
- Malignant melanoma: significance of disease-free interval. (1980) (22)
- Multileaf collimation cardiac shielding in breast radiotherapy: Cardiac doses are reduced, but at what cost? (2013) (22)
- The effectiveness of the routine clinic visit in the follow-up of breast cancer patients: analysis of a defined patient cohort. (1998) (22)
- Acute toxicity in pelvic radiotherapy; a randomised trial of conformal versus conventional treatment. (1997) (21)
- Hypofractionation for early breast cancer: First results of the UK standardization of breast radiotherapy (START) trials (2007) (21)
- Abstract S4-1: The UK START (Standardisation of Breast Radiotherapy) Trials: 10-year follow-up results (2012) (20)
- Test of association between variant tgβ1 alleles and late adverse effects of breast radiotherapy. (2010) (20)
- Postmastectomy radiotherapy: will the selective use of postmastectomy radiotherapy study end the debate? (2009) (19)
- Intratumoural hydrogen peroxide with radiotherapy in locally advanced breast cancer: results from a Phase I clinical trial. (2020) (19)
- The impact of dose heterogeneity on late normal tissue complication risk after hypofractionated whole breast radiotherapy. (2012) (18)
- Patterns of breast relapse after local excision +/- radiotherapy for early stage breast cancer. (1988) (18)
- Double-blind randomised phase II study of hyperbaric oxygen in patients with radiation-induced brachial plexopathy. (2005) (18)
- Dynamic MRI of breast hardness following radiation treatment (2003) (17)
- Magnetic resonance imaging of induration in the irradiated breast. (2002) (17)
- Effect of breast-duct anatomy and wound-healing responses on local tumour recurrence after primary surgery for early breast cancer. (2009) (17)
- Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity (2015) (17)
- Chemotherapy and radiotherapy for advanced testicular nonseminoma (1983) (17)
- 7LBA A 5-fraction regimen of adjuvant radiotherapy for women with early breast cancer: first analysis of the randomised UK FAST trial (ISRCTN62488883, CRUKE/04/015) (2009) (16)
- The use of ultrasound to measure breast thickness to select electron energies for breast boost radiotherapy. (1994) (16)
- Multicentric breast cancer: clonality and prognostic studies (2011) (16)
- Randomised comparison of a 13 fraction schedule with a conventional 25 fraction schedule of radiotherapy after local excision of early breast cancer: preliminary analysis (1993) (16)
- Localising the tumour bed in breast radiotherapy. (2010) (15)
- Does participation in clinical trials influence the implementation of new techniques? A look at changing techniques in breast radiotherapy in the UK. (2012) (15)
- Pushing the limits of hypofractionation for adjuvant whole breast radiotherapy. (2010) (15)
- Can patient-reported outcomes be used instead of clinician-reported outcomes and photographs as primary endpoints of late normal tissue effects in breast radiotherapy trials? Results from the IMPORT LOW trial (2019) (14)
- Five-fraction Radiotherapy for Breast Cancer: FAST-Forward to Implementation. (2021) (14)
- Ductal carcinoma in situ of the breast (2012) (14)
- Factors affecting relapse following chemotherapy for Hodgkin's disease. (1982) (12)
- Treatment of breast cancer (1994) (12)
- Where Do We Look for Markers of Radiotherapy Fraction Size Sensitivity? (2015) (12)
- OC-0595: FAST-Forward phase 3 RCT of 1-week hypofractionated breast radiotherapy:3-year normal tissue effects (2018) (12)
- Hypofractionated Adjuvant Whole Breast Radiotherapy: Progress and Prospects (2010) (12)
- Principles and practice of radiotherapy. (2001) (12)
- Chemotherapy and radiotherapy for advanced testicular non-seminoma. I. The influence of sequence and timing of drugs and radiation on the appearance of normal tissue damage. (1983) (12)
- Abstract GS4-05: Dose escalated simultaneous integrated boost radiotherapy for women treated by breast conservation surgery for early breast cancer: 3-year adverse effects in the IMPORT HIGH trial (CRUK/06/003) (2019) (11)
- Cytokine levels as biomarkers of radiation fibrosis in patients treated with breast radiotherapy (2014) (11)
- Correlation between DNA damage responses of skin to a test dose of radiation and late adverse effects of earlier breast radiotherapy. (2016) (11)
- CNS relapse despite prophylactic cranial irradiation (PCI) in small cell lung cancer (SCLC). (1986) (11)
- Molecular Biology for Oncologists (1993) (11)
- Guidelines for locoregional therapy in primary breast cancer in developing countries: The results of an expert panel at the 8th Annual Women's Cancer Initiative – Tata Memorial Hospital (WCI-TMH) Conference (2012) (11)
- High-dose cyclophosphamide with autologous bone marrow rescue after conventional chemotherapy in the treatment of small cell lung carcinoma (2004) (11)
- Carboplatin (JM8), etoposide (VP16) and thoracic irradiation for small cell lung cancer (S.C.L.C.): an evaluation of lung toxicity. (1988) (11)
- The Linear-Quadratic Model and Implications for Fractionation. (2019) (11)
- Non-surgical management of early breast cancer in the United Kingdom: The role and practice of radiotherapy (1995) (10)
- The treatment of carcinoma of the cervix and endometrium using the cathetron at the Middlesex Hospital. (1979) (10)
- A study testing the routine use of ultrasound measurements when selecting the electron energy for breast boost radiotherapy. (1999) (10)
- 19 Fractionation sensitivity of breast cancer. Results of a randomised trial (2003) (10)
- Ovarian ablation (OA) in pre-menopausal women with early breast cancer prescribed 5 years tamoxifen (T) or T plus chemotherapy (CT)–results from the UK NCRI Adjuvant Breast Cancer (ABC) international trial of 2,144 patients (2004) (10)
- Breast radiotherapy and heart disease - where are we now? (2013) (10)
- Response to letter re: Prediction of normal tissue tolerance from in vitro cellular radiation sensitivity (1995) (9)
- P15 The IMPORT Gold Seed Study: Evaluation of Tumour Bed Localisation and Image-guided Radiotherapy for Breast Cancer (2007) (9)
- A multicentre observational study evaluating image-guided radiotherapy for more accurate partial-breast intensity-modulated radiotherapy: comparison with standard imaging technique (2014) (9)
- Tumour growth delay as a clinical endpoint for the measurement of radiation response. (1986) (9)
- Hypofractionated radiotherapy in early breast cancer: Clinical, dosimetric and radio-genomic issues. (2015) (9)
- The severity of late skin damage related to fraction size in women treated by radiotherapy after mastectomy. (1987) (9)
- Early stage breast cancer: treatment options and results. (1991) (8)
- Sequential or concurrent tamoxifen and radiotherapy: to see or not to see--that is the question! (2005) (8)
- TP53 modulates radiotherapy fraction size sensitivity in normal and malignant cells (2021) (7)
- OC-0291 IMPORT HIGH trial: Dose escalated simultaneous integrated boost radiotherapy in early breast cancer (2021) (7)
- Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT) (2009) (7)
- Simulation of a radiobiology facility for the Centre for the Clinical Application of Particles. (2019) (7)
- Changes in mast cell number and stem cell factor expression in human skin after radiotherapy for breast cancer. (2014) (7)
- Mixing anthracyclines and radiotherapy in early breast cancer: how safe is it? (1996) (7)
- FFPE breast tumour blocks provide reliable sources of both germline and malignant DNA for investigation of genetic determinants of individual tumour responses to treatment (2018) (7)
- Benefits of post-mastectomy radiotherapy (1997) (7)
- Matching supraclavicular fields to the extent of axillary surgery in women prescribed radiotherapy for early stage carcinoma of the breast. (2005) (7)
- Abstract P1-13-03: Mature analysis of UK Taxotere as Adjuvant Chemotherapy (TACT) trial (CRUK 01/001); effects of treatment and characterisation of patterns of breast cancer relapse. (2012) (6)
- The UK START Trials: 10-Year Follow-Up Results (2013) (6)
- Patterns of relapse following radiotherapy for Hodgkin's disease. (1982) (6)
- Gene expression profiling of human dermal fibroblasts exposed to bleomycin sulphate does not differentiate between radiation sensitive and control patients (2011) (6)
- Duration of chemotherapy in advanced breast carcinoma (1990) (6)
- Correlation between the radiation responses of fibroblasts cultured from individual patients and the risk of late reaction after breast radiotherapy. (2016) (6)
- Randomised single centre double-blind placebo controlled phase II trial of Tocovid SupraBio in combination with pentoxifylline in patients suffering long-term gastrointestinal adverse effects of radiotherapy for pelvic cancer: the PPALM study. (2022) (6)
- Study design in the evaluation of combined radiotherapy plus chemotherapy. (1990) (6)
- Consensus document on staging for breast cancer (1994) (5)
- Breast conservation and management of early breast cancer. (1990) (5)
- Double-blind randomised phase II study of hyperbaric oxygen in patients with radiation-induced brachial plexopathy. Author's reply (2005) (5)
- Radiotherapy for bone pain: is a single fraction good enough? UK Multicentre Bone Pain Trial Collaborators. (1994) (5)
- Radiation in the context of multidisciplinary approaches: radiotherapy and locally advanced breast cancer (2001) (5)
- What are cancer genes, and how do they upset cell behaviour? (1992) (5)
- Targeted Intraoperative Radiotherapy for Early Breast Cancer. (2020) (5)
- Management of Radiation Injuries to the Bowel Associated with Treatment of Uterine Carcinoma by Radiotherapy: Preliminary Communication (1979) (5)
- A multicentre study of the evidence for customized margins in photon breast boost radiotherapy (2015) (5)
- Is current evidence about intraoperative partial breast irradiation sufficient for broad implementation in clinical practice? (2014) (4)
- Ovarian ablation (OA) in pre-menopausal women with early breast cancer prescribed 5 years tamoxifen (T) or T plus chemotherapy (CT)-results from the UK NCRI Adjuvant Breast Cancer (ABC) international trial of 2,144 patients. (2004) (4)
- Hypofractionation for early breast cancer: first results of the UK standardisation of breast radiotherapy (START) Trials, On behalf of the START Trialists (2007) (4)
- Fractionation in radiotherapy: results of a Canadian randomised clinical trial (2005) (4)
- Role of radiotherapy in the management of bone metastases from breast cancer. (1985) (4)
- Post-mastectomy radiotherapy: is it cure after all? (1994) (4)
- A toast to the silver anniversary of Clinical Oncology: a quarter of a century of advances in evidence-based radiation dose fractionation. (2014) (4)
- Assessing breast cosmesis after radiotherapy: what do we want to measure? (2005) (4)
- OC-0135 CAN PATIENT REPORTED OUTCOME MEASURES REPLACE CLINICAL ASSESSMENTS IN BREAST RADIOTHERAPY TRIALS? (2012) (4)
- How Low Can You Go? The Radiobiology of Hypofractionation. (2022) (4)
- In Regard to Vaidya et al. (2015) (4)
- Latest developments in local treatment: radiotherapy for early breast cancer. (2005) (4)
- Quality assurance analysis of participating centres' protocol compliance to a UK multicentre hypofractionated breast (FAST) trial. (2012) (3)
- Re: Start of cheaper technique for breast cancer is delayed in UK despite adoption elsewhere (2015) (3)
- Management of breast cancer Refer women to multidisciplinary breast clinics (1994) (3)
- Haste makes waste: Are the data regarding TARGIT-A IORT ready for prime time? (2014) (3)
- Molecular biology for clinical oncologists (2nd ed.) (1996) (3)
- From 25 Fractions to Five: How Hypofractionation has Revolutionised Adjuvant Breast Radiotherapy. (2022) (3)
- Intensity-modulated Radiotherapy for the Treatment of Breast Cancer. (2013) (3)
- Quality of life after breast radiotherapy – Authors' reply (2010) (2)
- OC-0101 First results of FAST-Forward phase 3 RCT nodal substudy: 3-year normal tissue effects (2022) (2)
- Selective avoidance of lymphatic radiotherapy in the conservative management of women with early breast cancer. (1992) (2)
- OC-0387: The UK HeartSpare Study (Stage II): Multicentre evaluation of a voluntary breath-hold technique (2015) (2)
- Modelling the cost-effectiveness of first, second and third generation polychemotherapy regimens in women with early breast cancer who have differing prognoses. (2009) (2)
- Abstract PL-3: Breast Radiotherapy: Fractionation and Other Fashions (2012) (2)
- The effects of radiotherapy on normal tissues in early breast cancer: results of the UK standardisation of breast radiotherapy (START) trials. (2008) (2)
- A longitudinal analysis of patient reported outcomes over 5 years in the IMPORT LOW (partial breast radiotherapy after breast conservation surgery) phase III randomised controlled trial (2018) (2)
- Intercalated radio-chemotherapy in small cell lung cancer: toxicity and implications for future regimens. (1991) (2)
- The Use of Compensators and Multiple Static Fields for IMRT of the Breast (2000) (2)
- Quality assurance in conservative treatment of early breast cancer, a consensus meeting. December 13-14, 1990, Tübingen, Germany. (1991) (2)
- Novel Radiotherapy regimens. (2004) (1)
- Late effects of breast radiotherapy (2014) (1)
- O-17 Implanted gold seeds for tumour bed localisation and image-guided radiotherapy (2007) (1)
- A multi-institutional investigation of image-guided radiotherapy for breast cancer (2014) (1)
- Quality of life (QL) assessment of anxiety and depression in the START Trial for women with early stage breast cancer, on behalf of the Trial Management Group (2003) (1)
- Comparison of In Vivo Skin and In Vitro Blood Lymphocyte Models for the Prediction of Late Normal Tissue Responses in Breast Radiation Therapy Patients (2013) (1)
- OUTCOME INDICATORS FOR BREAST CANCER (1999) (1)
- Partial breast radiotherapy after breast conservation surgery for early breast cancer: 5-year outcomes from the IMPORT LOW (CRUK/06/003) phase III randomised controlled trial (2017) (1)
- In response to professor Beck-Bornholdt (1995) (1)
- Radiotherapy Delivery for Women with Early Breast Cancer (2010) (1)
- OC-0610: FAST-Forward phase 3 RCT of 1-week hypofractionated breast radiotherapy: 5-year results (2020) (1)
- OC-0061: Big-RT: Big Data analysis to identify predictors of radiotherapy toxicity for personalised treatment (2018) (1)
- Transforming growth factor beta: relevance to radiotherapy. (1995) (1)
- Measurement of Human Normal Tissue and Tumour Responses (1988) (1)
- Book reviewMammary tumorigenesis and malignant progression (cancer treatment and research; vol. 71), R.E. Dickson, M.E. Lippmman (Eds.) (1994), Pages: 360; Price £151.75; Hard cover. ISBN 0-7923-2647-4 (1995) (1)
- Cost-effectiveness of 5 fraction and partial breast radiotherapy for early breast cancer in the UK: model-based multi-trial analysis (2022) (1)
- Hyperbaric oxygen therapy for chronic bowel dysfunction after pelvic radiotherapy - Authors' reply. (2016) (1)
- Reply to Goodare et al. Re: Do Patient-reported Outcome Measures Agree with Clinical and Photographic Assessments of Normal Tissue Effects after Breast Radiotherapy? (2016) (1)
- OC-0380: Cell cycle checkpoint modulates radiotherapy fraction size sensitivity in normal and malignant cells (2018) (1)
- OC-0392: Tumour characteristics associated with local relapse after hypofractionated radiotherapy in early breast cancer (2015) (1)
- Radiotherapy for bone metastasis are single and multiple fractions equivalent (1993) (1)
- RELATION BETWEEN BREAST TUMOUR GROWTH RATE AND METASTATTC POTENTIAL (1986) (1)
- 123 Klaas Breur award Hypofractionated radiotherapy in early breast cancer and implications for intensity modulated radiotherapy (2007) (1)
- FAST-Forward Phase III Randomised Controlled Trial of 1-Week Hypofractionated Breast Radiotherapy: 5-Year Results for Efficacy and Late Normal Tissue Effects (2020) (1)
- OC-0156: Concordance of patient reported outcomes with clinician and photographic assessments in IMPORT LOW (2018) (1)
- Patient and anatomical selectivity in postoperative radiotherapy for early breast cancer: a British perspective. (1992) (1)
- 2026 ORAL Results of the UK standardisation of breast radiotherapy (START) trials testing hypofractionation for early breast cancer – on behalf of the START trials centres (2007) (1)
- SP-0314: Partial breast radiotherapy after breast conservation: 5 year outcomes from the IMPORT LOW (CRUK/06/003) phase III trial (2017) (1)
- Status of hypofractionated radiotherapy in breast cancer (2005) (1)
- Targeted radiotherapy for early breast cancer – Authors' reply (2018) (1)
- Radiotherapy hypofractionation in early breast cancer – Author's reply (2008) (0)
- Clonality studies in multicentric breast cancer using P53 mutations and RNA polymorphisms (1993) (0)
- Radiotherapy hypofractionation in early breast cancer - Reply (2008) (0)
- HeartSpare Study ( Stage IB ) : Randomised comparison of the voluntary breath-hold technique and prone treatment in larger-breasted women (2015) (0)
- PD-0430: Results from the radiotherapy quality assurance programme for the FAST-Forward breast trial (2015) (0)
- Radiation Benefits Many but Not Necessarily All Patients With BC (2014) (0)
- 553 POSTER Stem cell mobilisation by hyperbaric oxygen (HBO) (2007) (0)
- Normal-tissue complication modelling for breast tissue (2014) (0)
- 911 poster BIOMARKERS OF RADIATION FIBROSIS IN BREAST CANCER: A METHODS VALIDATION STUDY FOR INTERLEUKIN 6 (2011) (0)
- Quality of life (QL) in women treated for early stage breast cancer entering the START (Standardisation of Breast Radiotherapy) Trial. On behalf of the Trial Management Group (2002) (0)
- Pre conference Oncoplasty & Breast Reconstruction Workshop (2012) (0)
- Patient reported outcomes following lymphatic radiotherapy: Results from the UK START (Standardisation of Breast Radiotherapy) trials. Presented on behalf of the START Trial Management Group (2017) (0)
- EDITORIAL: RADIOTHERAPY DELIVERY FOR WOMEN WITH EARLY BREAST CANCER (2010) (0)
- SP-0626: This house believes that larger fraction sizes will be the standard-of-care for the majority of curative treatments by 2025 (2016) (0)
- EP-1592 DSB REPAIR AND INDUCTION OF APOPTOSIS IN EX VIVO IRRADIATED BLOOD LYMPHOCYTES OF BREAST CANCER PATIENTS (2012) (0)
- Intraoperative Radiotherapy: Is it Ready for Prime Time? (2015) (0)
- 902 ORAL Expression of KIT (c-Kit; CD117) is reduced after radiation in normal human breast tissue: a study using cDNA array analysis of microdissected samples (2007) (0)
- Faculty Opinions recommendation of Effectiveness of radiation therapy for older women with early breast cancer. (2006) (0)
- EP-1575 INVESTIGATION OF INTERLEUKIN 6 AS A BIOMARKER OF RADIATION FIBROSIS IN BREAST CANCER (2012) (0)
- E1. Research progress and priorities in breast radiotherapy (2010) (0)
- Tangential breast irradiation (1995) (0)
- ESTRO consensus guidelines ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer (2015) (0)
- Acute normal tissue reaction (moist desquamation) in patients with early breast cancer treated with 30Gy in 6 fractions over 15 days: results of a pilot study. (2006) (0)
- Dose and fractionation regimens for breast cancer - Reply (2006) (0)
- Radiotherapy in early breast cancer (2006) (0)
- 3Genetic aspects of radiotherapy (1996) (0)
- General principles and practice of modern radiation oncology (2001) (0)
- Treatment at Brompton Hospital and Royal Marsden Hospital (1988) (0)
- Curietherapy at high dose rate (Cathetron). (1979) (0)
- Treatment of early breast cancer (1992) (0)
- Cytokine levels as biomarkers of radiation fibrosis in patients treated with breast radiotherapy (2014) (0)
- Book reviewConservation Surgery and Radiation Therapy in the Treatment of Operable Breast Cancer, J.M. Vaeth (Ed.), in: Frontiers of Radiation Therapy & Oncology, S. Karger (1983) (1983) (0)
- The Linear-Quadratic Model and Implications for Fractionation. (2019) (0)
- 416 UK patients are willing to donate biological material for sub-studies in clinical trials (2003) (0)
- 209 Radiotherapy in Breast Conservation (2012) (0)
- Productivity and health effects of radiotherapy (2003) (0)
- Second scientific meeting of the British Oncological Association. June 29-30, 1987, Oxford, UK. Abstracts. (1987) (0)
- SP-0438 HYPOFRACTIONATION: GENERAL OVERVIEW (2012) (0)
- Is there an association between late normal tissue response and tumour control after local tumour excision and radiotherapy for early breast cancer (2006) (0)
- INTRINSIC RADIOSENSIVITIY OF HUMAN FIBROBLASTS SEEMS TO BE UNABLE TO PREDICT NORMAL TISSUE RESPONSE TO RADIOTHERAPY : REGARDING WURM ET AL., IJROBP 60 :265-633; 1994. AUTHOR'S REPLIES (1995) (0)
- Molecular biology for clinical oncologists. (1993) (0)
- 394 poster IMPORT-LOW PARTIAL BREAST OUTLINING STUDY: USE OF A TRAINING PROTOCOL TO IMPROVE INTER-OBSERVER CONCORDANCE (2011) (0)
- The effect of patient and treatment characteristics on set-up accuracy (2014) (0)
- ATM rs1801516 SNP and toxicity after radiotherapy (2017) (0)
- E13. Hypofractionated radiotherapy for breast cancer (2012) (0)
- Radiotherapy fraction size sensitivity is modulated by DNA repair systems (2010) (0)
- Subgroup Analysis of Functional Associations Between In Vitro Radiation Response of Fibroblasts and Late Toxicity After Breast Radiation Therapy (2016) (0)
- Targeted radiotherapy for early breast cancer reply (2018) (0)
- United Kingdom Experience: Clinical Trial Evolution, Techniques, Data, and Toxicity (2016) (0)
- OC-0075: Normal tissue complication probability parameters for breast fibrosis: pooled results from two randomised trials (2013) (0)
- A critical review of the relationship between irradiated breast volume and late breast tissue complications (2014) (0)
- Cancer Treatment: End-point Evaluation, Basil A. Stoll (Ed.), in: New Horizons in Oncology, Vol. 2. John Wiley & Sons, Amsterdam (1983) (1984) (0)
- 5124. Left anterior descending coronary artery (LAD) doses from breast radiotherapy: is prone treatment positioning beneficial? (2009) (0)
- 236 speaker PARTIAL BREAST RADIOTHERAPY: WHAT DO WE NEED TO KNOW? (2011) (0)
- Session 10: Radiotherapy: Innovation and long term effects in early breast cancer (2015) (0)
- Breast cancer. Setting priorities for effectiveness research, K.N. Lohr (Ed.). National Academy Press, (1991.), 64; (1992) (0)
- PO-0915: High p53 levels after a radiotherapy dose, but not residual DNA DSBs, are associated with late normal tissue reactions (2013) (0)
- Topical Reviews in Radiotherapy and Oncology, Volume One. Edited by T. J. Deeley. John Wright & Sons Ltd. 274 pp. £13.50. (1981) (0)
- Hypofractionated whole breast irradiation (2008) (0)
- 189 INVITED Does everyone need breast radiotherapy (2007) (0)
- 57 Role of hyperbaric oxygen (HBO) therapy in radiation-damaged tissues (2000) (0)
- Abstract P3-06-09: Test of association between Ki67 index of early breast cancer and local relapse after adjuvant hypofractionated radiotherapy. (2012) (0)
- patterns of Relapse ttodgkin's Disease following Radiotherapy for (1982) (0)
- Axillary nodes dissection in breast cancer. (1992) (0)
- OC-0281 Tumour reoxygenation by intratumoural hydrogen peroxide: a mechanism for enhanced radiosensitivity (2021) (0)
- 276Radiotherapy fractionation sensitivity: Proposals for a UK national trial (1996) (0)
- Treatment of breast cancer. (1994) (0)
- Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5,456 breast and prostate cancer patients (2017) (0)
- Faculty Opinions recommendation of Predicting a local recurrence after breast-conserving therapy by gene expression profiling. (2006) (0)
- Scoring Photographic Assessment of Normal Tissue Effects after Radiotherapy for Early Breast Cancer (2007) (0)
- PO-0991: p53 and in vitro radiation response of fibroblasts from RT-sensitive and -resistant patients (2016) (0)
- Faculty Opinions recommendation of Coronary artery findings after left-sided compared with right-sided radiation treatment for early-stage breast cancer. (2007) (0)
- Modulation of late adverse effects of curative radiation therapy for cancer (Chapter 17) (2004) (0)
- Breast (Chapter 4) (2006) (0)
- TANGENTIAL BREAST IRRADIATION. AUTHORS' REPLY (1995) (0)
- Radiotherapy in small cell cancer of the lung (1984) (0)
- Abstract ES4-3: What is the value of internal mammary chain RT and how can we deliver it safely? (2015) (0)
- 367 INVITED Summary: Concept, Rationale, Evidence and Future Directions (2011) (0)
- Possession of the ATM Codon 1853 SNP is Associated With an Increased Risk for Radiation-Induced Toxicity (2014) (0)
- DNA Double-strand Break Repair and Induction of Apoptosis in Relation to Late Normal Tissue Responses Following Radiation Therapy for Early Breast Cancer (2012) (0)
- DNA double-strand break repair and induction of apoptosis in ex vivo irradiated blood lymphocytes in relation to late normal tissue reactions following breast radiotherapy (2014) (0)
- 5126 Ipsilateral breast tumour relapse: local recurrence versus new primary and the effect of whole breast radiotherapy on the rate of new primaries (2009) (0)
- Breast cancer radiation therapy – Authors' reply (2020) (0)
- Quality of life after breast radiotherapy Reply (2010) (0)
- EP-1784: Clinical impact of IMPORT HIGH trial (CRUK/06/003) on breast radiotherapy in the United Kingdom (2014) (0)
- 1100 POSTER Body image and breast symptoms in early breast cancer: first results of the UK standardisation of breast radiotherapy (START) trials (2007) (0)
- Minimising oncological treatment of early breast cancer (2008) (0)
- The role of HIF-1 in the neo-vascularization of the rectal mucosa after radiation therapy (2016) (0)
- Corrigendum to “Randomised phase II trial of hyperbaric oxygen therapy in patients with chronic arm lymphoedema after radiotherapy for cancer” [Radiother Oncol 97 (2010) 101–107] (2011) (0)
- A randomised trial testing observation (no radiotherapy) against radiotherapy in women with low-risk completely excised oestrogen receptor (ER) positive ductal carcinoma in situ (DCIS) of the breast on adjuvant endocrine therapy (2004) (0)
- Treatment of early breast cancer. (1992) (0)
- SP-0390 Hypofractionation for breast cancer and some other things (2021) (0)
- Mixing anthracyclines and radiotherapy in early breast cancer: how safe is it? (1996) (0)
- Assessment of Tumour Response, B.W. Hancock (Ed.). Martinus Nijhoff, Philadelphia (1982) (1983) (0)
- 2037 POSTER. The effect of hypofractionation and radiation dosimetry on the incidence of symptomatic rib fractures in women treated with radiotherapy for early breast cancer in the UK standardisation of breast radiotherapy (START) Trials (2007) (0)
- CASE MATCHED CONTROL STUDY OF FIBROBLAST GENE EXPRESSION AND PHENOTYPE RELATED TO LATE REACTION AFTER BREAST CANCER RADIOTHERAPY (2011) (0)
- Radiotherapy fractionation: results of a pilot study to the NCRI standardisation of radiotherapy (START) trial (2004) (0)
- Investigating the role of DNA double strand break repair in determining sensitivity to radiotherapy fraction size (2014) (0)
- 13 New radiotherapy strategies in breast cancer: Partial breast radiotherapy (2006) (0)
- Dose and fractionation regimens for breast cancer – Authors' reply (2006) (0)
- SP-0373 Fractionation and breast cancer: towards more efficient schedules (2019) (0)
- VOLUME EFFECTS FOR LATE ADVERSE EFFECTS AFTER ADJUVANT BREAST RADIOTHERAPY (2011) (0)
- The Role of Partial Breast Radiotherapy in Women with Early Breast Cancer (2007) (0)
- Faculty Opinions recommendation of HER2 and responsiveness of breast cancer to adjuvant chemotherapy. (2006) (0)
- EP-1315: KORTUC phase I/II trial testing a novel radiation sensitiser in breast cancer: preliminary results (2018) (0)
- SP-0006: Patient reported outcomes versus clinical assessment of radiotherapy adverse effects (2013) (0)
- How soon do patients return to work after radiotherapy for early stage breast cancer? on behalf of the START Trial Management Group (2004) (0)
- E06. Regional control matters in breast cancer (2014) (0)
- Comparison of in vivo skin and in vitro blood lymphocyte models for the prediction of late normal tissue responses in breast radiotherapy (RT) patients. (2013) (0)
- Partial breast irradiation margins with two deep-inspiratory breath-hold techniques (2013) (0)
- Individual in vitro fibroblast sensitivity predicts for normal tissue response to radiotherapy (1993) (0)
- SP-0095 HYPOFRACTIONATION AND PBRT: WHAT DO WE NEED TO THINK ABOUT? (2012) (0)
- Erratum to "Correlation between the radiation responses of fibroblasts cultured from individual patients and the risk of late reaction after breast radiotherapy" [Cancer Lett. 374/2 (2016) 324-330]. (2016) (0)
- Radiotherapy following excision of early breast cancer (2009) (0)
- Clinical Trials of management of early breast cancer (Chapter 14) (2006) (0)
- Overview of Hypofractionation in Breast Radiotherapy (2011) (0)
- SP-0649: Hyperbaric oxygen therapy for the treatment of the late effects of radiotherapy (2018) (0)
- SP-0439: Hypo-fractionation for early breast cancer (2014) (0)
- Radiation-induced Gene Expression and Differentiation Status of Fibroblast Cultures from Breast Cancer Patients with and without Late Reaction to Radiotherapy (2010) (0)
- 2081 POSTER. Scoring photographic assessment of normal tissue effects after radiotherapy for early breast cancer – a comparison of two different methods (2007) (0)
- Response to D. Woolf and M. Keshtgar's reply to: breast radiotherapy and heart disease - where are we now? (2014) (0)
- Update of the START (Standardisation of Breast Radiotherapy) trial on behalf of the trial management group (2002) (0)
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