Jon Beckwith
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American biochemist
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Jon Beckwithbiology Degrees
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Biochemistry
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Biology
Jon Beckwith's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Jon Beckwith Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jonathan Roger Beckwith is an American microbiologist and geneticist. He is the American Cancer Society Professor in the Department of Microbiology and Immunobiology at Harvard Medical School in Boston, Massachusetts.
Jon Beckwith's Published Works
Published Works
- Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter (1995) (4860)
- TnphoA: a transposon probe for protein export signals. (1985) (991)
- Identification of a protein required for disulfide bond formation in vivo (1991) (931)
- Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm. (1999) (659)
- The Role of the Thioredoxin and Glutaredoxin Pathways in Reducing Protein Disulfide Bonds in the Escherichia coliCytoplasm* (1997) (645)
- The lactose operon (1970) (580)
- Protein disulfide bond formation in prokaryotes. (2003) (543)
- A genetic approach to analyzing membrane protein topology. (1986) (540)
- Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide status. (1999) (521)
- Discrimination as a consequence of genetic testing. (1992) (476)
- E. coli mutant pleiotropically defective in the export of secreted proteins (1981) (439)
- Mutations that allow disulfide bond formation in the cytoplasm of Escherichia coli. (1993) (439)
- Disulfide bond formation in the Escherichia coli cytoplasm: an in vivo role reversal for the thioredoxins (1998) (436)
- Diverse Paths to Midcell: Assembly of the Bacterial Cell Division Machinery (2005) (429)
- A pathway for disulfide bond formation in vivo. (1993) (404)
- Localization of FtsI (PBP3) to the Septal Ring Requires Its Membrane Anchor, the Z Ring, FtsA, FtsQ, and FtsL (1999) (401)
- Characterization of degP, a gene required for proteolysis in the cell envelope and essential for growth of Escherichia coli at high temperature (1989) (392)
- Mechanism of activation of catabolite-sensitive genes: a positive control system. (1970) (382)
- An Escherichia coli mutation preventing degradation of abnormal periplasmic proteins. (1988) (373)
- Roles of thiol-redox pathways in bacteria. (2001) (339)
- SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF (1995) (325)
- Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system. (1997) (310)
- Regulation of a membrane component required for protein secretion in escherichia coli (1982) (298)
- Protein localization in E. coli: Is there a common step in the secretion of periplasmic and outer-membrane proteins? (1981) (295)
- Bridge over Troubled Waters Sensing Stress by Disulfide Bond Formation (1999) (291)
- An in vivo pathway for disulfide bond isomerization in Escherichia coli. (1996) (287)
- Mechanism of incorporation of cell envelope proteins in Escherichia coli. (1982) (275)
- The genetics of disulfide bond metabolism. (1998) (263)
- Uses of lac fusions for the study of biological problems. (1985) (261)
- Mutations that alter the signal sequence of alkaline phosphatase in Escherichia coli (1983) (253)
- Determinants of membrane protein topology. (1987) (249)
- Nonsense mutants and polarity in the lac operon of Escherichia coli. (1965) (242)
- Use of gene fusion to study secretion of maltose-binding protein into Escherichia coli periplasm (1979) (241)
- Evidence for specificity at an early step in protein export in Escherichia coli (1985) (241)
- Alkaline phosphatase fusions: sensors of subcellular location (1990) (236)
- Reduction of the periplasmic disulfide bond isomerase, DsbC, occurs by passage of electrons from cytoplasmic thioredoxin (1997) (234)
- Bacterial species exhibit diversity in their mechanisms and capacity for protein disulfide bond formation (2008) (228)
- Mutations in a new gene, secB, cause defective protein localization in Escherichia coli (1983) (224)
- SecD and SecF facilitate protein export in Escherichia coli. (1994) (219)
- A signal sequence is not required for protein export in prlA mutants of Escherichia coli. (1993) (219)
- Mutations which alter the function of the signal sequence of the maltose binding protein of Escherichia coli (1980) (217)
- Snapshots of DsbA in Action: Detection of Proteins in the Process of Oxidative Folding (2004) (215)
- A complex of the Escherichia coli cell division proteins FtsL, FtsB and FtsQ forms independently of its localization to the septal region (2004) (214)
- Inactivation of FtsI inhibits constriction of the FtsZ cytokinetic ring and delays the assembly of FtsZ rings at potential division sites. (1997) (213)
- Ochre mutants, a new class of suppressible nonsense mutants (1965) (213)
- FtsQ, FtsL and FtsI require FtsK, but not FtsN, for co‐localization with FtsZ during Escherichia coli cell division (2001) (211)
- The role of charged amino acids in the localization of secreted and membrane proteins (1990) (210)
- Coordination of the synthesis of the enzymes in the pyrimidine pathway of E. coli. (1962) (206)
- Protein Translocation in the Three Domains of Life: Variations on a Theme (1997) (202)
- The DsbA Signal Sequence Directs Efficient, Cotranslational Export of Passenger Proteins to the Escherichia coli Periplasm via the Signal Recognition Particle Pathway (2003) (201)
- The use of transposon TnphoA to detect genes for cell envelope proteins subject to a common regulatory stimulus. Analysis of osmotically regulated genes in Escherichia coli. (1987) (200)
- Escherichia coli alkaline phosphatase fails to acquire disulfide bonds when retained in the cytoplasm (1991) (199)
- Transmembrane Electron Transfer by the Membrane Protein DsbD Occurs via a Disulfide Bond Cascade (2000) (199)
- Genetic analysis of protein export in Escherichia coli. (1983) (198)
- Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli (1984) (193)
- Towards Single-Copy Gene Expression Systems Making Gene Cloning Physiologically Relevant: Lambda InCh, a Simple Escherichia coli Plasmid-Chromosome Shuttle System (2000) (187)
- Structure of a bacterial homolog of vitamin K epoxide reductase (2010) (183)
- NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. (2008) (175)
- FtsL, an Essential Cytoplasmic Membrane Protein Involved in Cell Division in Escherichia coli (1992) (175)
- The secD locus of E.coli codes for two membrane proteins required for protein export. (1990) (160)
- A bacterial virulence determinant encoded by lysogenic coliphage λ (1990) (160)
- Production of functional single-chain Fv antibodies in the cytoplasm of Escherichia coli. (2002) (157)
- Individual, family, and societal dimensions of genetic discrimination: A case study analysis (1996) (156)
- Mapping of suppressor loci in Escherichia coli. (1965) (156)
- Isolation of Pure lac Operon DNA* (1969) (156)
- Six conserved cysteines of the membrane protein DsbD are required for the transfer of electrons from the cytoplasm to the periplasm of Escherichia coli (1999) (155)
- Thioredoxin 2 Is Involved in the Oxidative Stress Response inEscherichia coli * (2000) (153)
- The Thioredoxin Superfamily: Redundancy, Specificity, and Gray-Area Genomics (1999) (153)
- Genetic analysis of the membrane insertion and topology of MalF, a cytoplasmic membrane protein of Escherichia coli. (1988) (153)
- Premature targeting of cell division proteins to midcell reveals hierarchies of protein interactions involved in divisome assembly (2006) (151)
- Assembly of cell division proteins at the E. coli cell center. (2002) (150)
- secD, a new gene involved in protein export in Escherichia coli (1987) (149)
- The secE gene encodes an integral membrane protein required for protein export in Escherichia coli. (1989) (148)
- Alteration of the amino terminus of the mature sequence of a periplasmic protein can severely affect protein export in Escherichia coli. (1988) (144)
- Septal Localization of FtsQ, an Essential Cell Division Protein in Escherichia coli (1999) (143)
- Premature targeting of a cell division protein to midcell allows dissection of divisome assembly in Escherichia coli. (2005) (142)
- Evidence that the pathway of disulfide bond formation in Escherichia coli involves interactions between the cysteines of DsbB and DsbA. (1995) (142)
- The FtsQ protein of Escherichia coli: membrane topology, abundance, and cell division phenotypes due to overproduction and insertion mutations (1991) (142)
- Genetic Characterization of Mutations Which Affect Catabolite-Sensitive Operons in Escherichia coli, Including Deletions of the Gene for Adenyl Cyclase (1973) (141)
- How many membrane proteins are there? (1998) (140)
- Transposition of the Lac region of E. coli. (1966) (140)
- One of three transmembrane stretches is sufficient for the functioning of the SecE protein, a membrane component of the E. coli secretion machinery. (1991) (139)
- Use of gene fusions to study outer membrane protein localization in Escherichia coli. (1977) (139)
- Use of Thioredoxin as a Reporter To Identify a Subset of Escherichia coli Signal Sequences That Promote Signal Recognition Particle-Dependent Translocation (2005) (138)
- RESTORATION OF OPERON ACTIVITY BY SUPPRESSORS. (1963) (137)
- Mechanisms of oxidative protein folding in the bacterial cell envelope. (2010) (135)
- The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal. (2007) (131)
- Directed transposition of the arabinose operon: a technique for the isolation of specialized transducing bacteriophages for any Escherichia coli gene. (1969) (131)
- Genetic analysis of membrane protein topology by a sandwich gene fusion approach. (1990) (131)
- Synthesis and processing of an Escherichia coli alkaline phosphatase precursor in vitro. (1977) (130)
- Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation. (1994) (129)
- IcsA, a polarly localized autotransporter with an atypical signal peptide, uses the Sec apparatus for secretion, although the Sec apparatus is circumferentially distributed (2003) (128)
- A mutation affecting the regulation of a secA-lacZ fusion defines a new sec gene. (1988) (126)
- Identification of a new gene (secA) and gene product involved in the secretion of envelope proteins in Escherichia coli (1982) (126)
- Conversion of a Peroxiredoxin into a Disulfide Reductase by a Triplet Repeat Expansion (2001) (126)
- The Nonconsecutive Disulfide Bond of Escherichia coli Phytase (AppA) Renders It Dependent on the Protein-disulfide Isomerase, DsbC* (2005) (123)
- A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli (2006) (123)
- The disulfide bond isomerase DsbC is activated by an immunoglobulin‐fold thiol oxidoreductase: crystal structure of the DsbC–DsbDα complex (2002) (122)
- Localization of the Escherichia coli cell division protein FtsI (PBP3) to the division site and cell pole (1997) (121)
- The bonds that tie: Catalyzed disulfide bond formation (1993) (120)
- bor gene of phage lambda, involved in serum resistance, encodes a widely conserved outer membrane lipoprotein (1995) (119)
- Transposition of the lac region of Escherichia coli. I. Inversion of the lac operon and transduction of lac by phi80. (1966) (119)
- Mutational alteration of the maximal level of Lac operon expression. (1966) (118)
- The Bacterial ATPase SecA Functions as a Monomer in Protein Translocation* (2005) (117)
- New Controlling Element in the Lac Operon of E. coli (1968) (116)
- Deletion of the Escherichia coli crp Gene (1975) (112)
- Rapid β-lactam-induced lysis requires successful assembly of the cell division machinery (2009) (110)
- Cloning and restriction mapping of the alkaline phosphatase structural gene (phoA) of Escherichia coli and generation of deletion mutants in vitro (1981) (110)
- The Cs sec mutants of Escherichia coli reflect the cold sensitivity of protein export itself. (1993) (106)
- Disulfide bond formation in prokaryotes: history, diversity and design. (2014) (105)
- Characterization of cold-sensitive secY mutants of Escherichia coli (1990) (105)
- Escherichia coli pleiotropic mutant that reduces amounts of several periplasmic and outer membrane proteins (1979) (105)
- Evidence for two sites in the lac promoter region. (1972) (105)
- Labeling of proteins with beta-galactosidase by gene fusion. Identification of a cytoplasmic membrane component of the Escherichia coli maltose transport system. (1980) (105)
- A DELETION ANALYSIS OF THE LAC OPERATOR REGION IN ESCHERICHIA COLI. (1964) (105)
- Domain-swapping analysis of FtsI, FtsL, and FtsQ, bitopic membrane proteins essential for cell division in Escherichia coli (1997) (104)
- Escherichia coli mutants accumulating the precursor of a secreted protein in the cytoplasm (1979) (103)
- Detecting Folding Intermediates of a Protein as It Passes through the Bacterial Translocation Channel (2009) (103)
- Four cysteines of the membrane protein DsbB act in concert to oxidize its substrate DsbA (2002) (103)
- The promoter-operator region of the lac operon of Escherichia coli. (1968) (101)
- Use of phoA fusions to study the topology of the Escherichia coli inner membrane protein leader peptidase (1989) (101)
- Transposition of the lac region of Escherichia coli: III. The mechanism of attachment of bacteriophage φ80 to the bacterial chromosome (1966) (100)
- Genetic and molecular characterization of the Escherichia coli secD operon and its products (1994) (100)
- The nucleotide sequence of the gene for malF protein, an inner membrane component of the maltose transport system of Escherichia coli. Repeated DNA sequences are found in the malE-malF intercistronic region. (1984) (96)
- Mutations in a new chromosomal gene of Escherichia coli K-12, pcnB, reduce plasmid copy number of pBR322 and its derivatives (1986) (96)
- Localization of FtsL to the Escherichia coli septal ring (1999) (96)
- The reductive enzyme thioredoxin 1 acts as an oxidant when it is exported to the Escherichia coli periplasm. (1998) (95)
- Electron Avenue Pathways of Disulfide Bond Formation and Isomerization (1999) (94)
- Disulfide Rearrangement Triggered by Translocon Assembly Controls Lipopolysaccharide Export (2012) (94)
- Positively charged amino acid residues can act as topogenic determinants in membrane proteins. (1989) (93)
- Signal sequence of alkaline phosphatase of Escherichia coli (1982) (92)
- The Sec-dependent pathway. (2013) (91)
- Genetic studies on the inability of beta-galactosidase to be translocated across the Escherichia coli cytoplasmic membrane (1989) (91)
- YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site (2002) (90)
- A mutant hunt for defects in membrane protein assembly yields mutations affecting the bacterial signal recognition particle and Sec machinery. (2000) (90)
- D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport (1984) (90)
- Disulfide bond formation in prokaryotes (2018) (88)
- Evolutionary domain fusion expanded the substrate specificity of the transmembrane electron transporter DsbD (2002) (88)
- Conversion of beta-galactosidase to a membrane-bound state by gene fusion. (1976) (88)
- Mutagens which cause deletions in Escherichia coli. (1969) (87)
- A mechanism for repressor action. (1969) (87)
- Analysis of the topology of a membrane protein by using a minimum number of alkaline phosphatase fusions (1993) (85)
- Diversity of Chemical Mechanisms in Thioredoxin Catalysis Revealed by Single-Molecule Force Spectroscopy (2009) (80)
- Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP. (1987) (78)
- Genetic fusions defining trp and lac operon regulatory elements. (1975) (78)
- Regulation of the Lac Operon (1967) (78)
- Gene function in prokaryotes (1983) (78)
- In vivo requirement for glutaredoxins and thioredoxins in the reduction of the ribonucleotide reductases of Escherichia coli. (2006) (77)
- Catabolite Sensitive Site of the lac Operon (1969) (73)
- Importance of Redox Potential for the in VivoFunction of the Cytoplasmic Disulfide Reductant Thioredoxin fromEscherichia coli * (1999) (70)
- Transposition of the lac Region to the gal Region of the Escherichia coli Chromosome: Isolation of λlac Transducing Bacteriophages (1971) (70)
- Effects of signal sequence mutations on the kinetics of alkaline phosphatase export to the periplasm in Escherichia coli (1986) (70)
- Genetic fatalism and social policy: the implications of behavior genetics research. (1993) (69)
- Targeting of signal sequenceless proteins for export in Escherichia coli with altered protein translocase. (1996) (68)
- Roles of a conserved arginine residue of DsbB in linking protein disulfide-bond-formation pathway to the respiratory chain of Escherichia coli. (2000) (67)
- Interactions of glutaredoxins, ribonucleotide reductase, and components of the DNA replication system of Escherichia coli. (2004) (67)
- Residues essential for the function of SecE, a membrane component of the Escherichia coli secretion apparatus, are located in a conserved cytoplasmic region. (1994) (67)
- Twin Studies of Political Behavior: Untenable Assumptions? (2008) (66)
- The nature of mutants in the lac promoter region. (1968) (66)
- Divisome under Construction: Distinct Domains of the Small Membrane Protein FtsB Are Necessary for Interaction with Multiple Cell Division Proteins (2009) (66)
- Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin (2009) (65)
- Role of the mature protein sequence of maltose-binding protein in its secretion across the E. coli cytoplasmic membrane (1981) (64)
- An adenosine 3':5'-cyclic monophosphate-binding protein that acts on the transcription process. (1971) (64)
- Disulfide bond formation by exported glutaredoxin indicates glutathione's presence in the E. coli periplasm (2009) (62)
- Escherichia coli alkaline phosphatase localized to the cytoplasm slowly acquires enzymatic activity in cells whose growth has been suspended: a caution for gene fusion studies (1995) (61)
- The primary pathway of protein export in E. coli (1991) (61)
- Fusions of the lac and trp Regions of the Escherichia coli Chromosome (1970) (61)
- Suppression of growth and protein secretion defects in Escherichia coli secA mutants by decreasing protein synthesis (1986) (61)
- Decoding signals for membrane protein assembly using alkaline phosphatase fusions. (1991) (61)
- Cell Division in Escherichia coli: Role of FtsL Domains in Septal Localization, Function, and Oligomerization (2000) (61)
- Membrane topology and mutational analysis of Mycobacterium tuberculosis VKOR, a protein involved in disulfide bond formation and a homologue of human vitamin K epoxide reductase. (2011) (61)
- Multiple Interaction Domains in FtsL, a Protein Component of the Widely Conserved Bacterial FtsLBQ Cell Division Complex (2010) (61)
- Molecular basis of DNA sequence recognition by the catabolite gene activator protein: detailed inferences from three mutations that alter DNA sequence specificity. (1984) (59)
- On the Functional Interchangeability, Oxidant versus Reductant, of Members of the Thioredoxin Superfamily (2000) (57)
- Mutant RNA polymerase of Escherichia coli terminates transcription in strains making defective rho factor. (1978) (56)
- Genetic Fusions of the lac Operon: A New Approach to the Study of Biological Processes (1980) (56)
- A New Family of Membrane Electron Transporters and Its Substrates, Including a New Cell Envelope Peroxiredoxin, Reveal a Broadened Reductive Capacity of the Oxidative Bacterial Cell Envelope (2012) (56)
- Analysis of ftsQ Mutant Alleles in Escherichia coli: Complementation, Septal Localization, and Recruitment of Downstream Cell Division Proteins (2002) (54)
- The genetic analysis of human behavior: a new era? (1992) (53)
- Mutants, Suppressors, and Wrinkled Colonies: Mutant Alleles of the Cell Division Gene ftsQ Point to Functional Domains in FtsQ and a Role for Domain 1C of FtsA in Divisome Assembly (2006) (53)
- Use of TnphoA to detect genes for exported proteins in Escherichia coli: identification of the plasmid-encoded gene for a periplasmic acid phosphatase (1987) (53)
- Genetic Screen Yields Mutations in Genes Encoding All Known Components of the Escherichia coli Signal Recognition Particle Pathway (2002) (52)
- Genetic analysis of protein export in Escherichia coli. (1990) (50)
- Direction of Transcription of a Regulatory Gene in E. coli (1968) (50)
- Proper insertion of a complex membrane protein in the absence of its amino-terminal export signal. (1991) (50)
- Analysis of genetic regulatory mechanisms. (1974) (48)
- In vitro construction and characterization of phoA-lacZ gene fusions in Escherichia coli (1983) (47)
- Role for the Nonessential N Terminus of FtsN in Divisome Assembly (2006) (47)
- Functions of thiol-disulfide oxidoreductases in E. coli: redox myths, realities, and practicalities. (2003) (47)
- In Vivo Analyses of Interactions between SecE and SecY, Core Components of the Escherichia coli Protein Translocation Machinery* (1996) (47)
- The unusual transmembrane electron transporter DsbD and its homologues: a bacterial family of disulfide reductases. (2004) (46)
- Cotranslational and posttranslational protein translocation in prokaryotic systems. (1986) (46)
- Role and location of the unusual redox-active cysteines in the hydrophobic domain of the transmembrane electron transporter DsbD (2003) (46)
- Redox‐active cysteines of a membrane electron transporter DsbD show dual compartment accessibility (2007) (46)
- A selection for mutants that interfere with folding of Escherichia coli thioredoxin-1 in vivo. (2005) (45)
- lac: The Genetic System (1980) (45)
- Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity. (2008) (44)
- Allelic amber and ochre suppressors. (1968) (44)
- Transcription termination at the end of the tryptophan operon of Escherichia coli. (1977) (44)
- Biotinylation in vivo as a sensitive indicator of protein secretion and membrane protein insertion (1996) (43)
- Escherichia coli 6S RNA is not essential for growth or protein secretion (1985) (43)
- Laboratory evolution of glutathione biosynthesis reveals natural compensatory pathways. (2011) (43)
- Molecular genetic analysis of membrane protein topology. (1988) (42)
- The product of gene secC is involved in the synthesis of exported proteins in E. coli (1984) (42)
- The prokaryotic enzyme DsbB may share key structural features with eukaryotic disulfide bond forming oxidoreductases (2005) (41)
- In vivo oxidative protein folding can be facilitated by oxidation–reduction cycling (2010) (41)
- Membrane insertion of the Escherichia coli MalF protein in cells with impaired secretion machinery. (1991) (41)
- Genetic studies on protein export in bacteria. (1986) (40)
- A historical view of social responsibility in genetics (1993) (40)
- Functional plasticity of a peroxidase allows evolution of diverse disulfide-reducing pathways (2008) (39)
- DsbC activation by the N-terminal domain of DsbD (2001) (39)
- Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria (2015) (39)
- Role of Leucine Zipper Motifs in Association of the Escherichia coli Cell Division Proteins FtsL and FtsB (2011) (39)
- Crystallization of DsbA, an Escherichia coli protein required for disulphide bond formation in vivo. (1993) (39)
- The topological analysis of integral cytoplasmic membrane proteins (1993) (38)
- Use of gene fusions to determine a partial signal sequence of alkaline phosphatase (1979) (38)
- Should we make a fuss? A case for social responsibility in science (2005) (38)
- Fusions of the lac operon to the transfer RNA gene tyrT of Escherichia coli. (1979) (38)
- Assembly of a hetero-oligomeric membrane protein complex. (1992) (37)
- Signal sequence mutations disrupt feedback between secretion of an exported protein and its synthesis in E. coli (1984) (36)
- BIOLOGICAL CHLORINATION. VIII. LATE INTERMEDIATES IN THE BIOSYNTHESIS OF CALDARIOMYCIN. (1963) (36)
- Cyclic Adenosine Monophosphate-Independent Mutants of the Lactose Operon of Escherichia coli (1973) (36)
- Reconsidering Genetic Antidiscrimination Legislation (1998) (35)
- Conserved Role of the Linker α-Helix of the Bacterial Disulfide Isomerase DsbC in the Avoidance of Misoxidation by DsbB* (2006) (35)
- Ribonucleotide reductases: influence of environment on synthesis and activity. (2006) (35)
- The dynamics of assembly of a cytoplasmic membrane protein in Escherichia coli. (1992) (34)
- Sites within gene lacZ of Escherichia coli for formation of active hybrid beta-galactosidase molecules (1979) (34)
- Distinguishing genetic from nongenetic medical tests: Some implications for antidiscrimination legislation (1998) (33)
- Gene fusion analysis of membrane protein topology: a direct comparison of alkaline phosphatase and beta-lactamase fusions (1994) (32)
- Processing of alkaline phosphatase precursor to the mature enzyme by an Escherichia coli inner membrane preparation (1980) (32)
- Two Snapshots of Electron Transport across the Membrane (2009) (31)
- Escherichia coli K-12 mutants that allow transport of maltose via the beta-galactoside transport system (1979) (31)
- Lambda repressor N-terminal DNA-binding domain as an assay for protein transmembrane segment interactions in vivo. (1998) (30)
- Research Article 16: Mutants Missing a Factor Necessary for the Expression of Catabolite-Sensitive Operons in E. coli (1970) (29)
- Use of gene fusions to isolate promoter mutants in the transfer RNA gene tyrT of Escherichia coli. (1979) (29)
- Overexpression of the rhodanese PspE, a single cysteine‐containing protein, restores disulphide bond formation to an Escherichia coli strain lacking DsbA (2012) (28)
- Biological chlorination. II. The biosynthesis of 5-chlorolevulinic acid. (1959) (28)
- Deletion map of the Escherichia coli structural gene for alkaline phosphatase, phoA (1981) (28)
- The Mechanism of Activation of Catabolite-Sensitive Genes (1970) (28)
- Artificial Septal Targeting of Bacillus subtilis Cell Division Proteins in Escherichia coli: an Interspecies Approach to the Study of Protein-Protein Interactions in Multiprotein Complexes (2008) (27)
- Deletions of distal sequence affect termination of transcription at the end of the tryptophan operon in E. coli (1980) (27)
- Illusions of scientific legitimacy: misrepresented science in the direct-to-consumer genetic-testing marketplace. (2010) (27)
- Functional activity of eukaryotic signal sequences in Escherichia coli: the ovalbumin family of serine protease inhibitors. (2004) (27)
- The characterization of a new type of F-prime factor in Escherichia coli K12 (1964) (27)
- In vitro Transcription of the lac Operon Genes (1970) (26)
- Contribution of the FtsQ Transmembrane Segment to Localization to the Cell Division Site (2007) (26)
- SOCIAL AND POLITICAL USES OF GENETICS IN THE UNITED STATES: PAST AND PRESENT * (1976) (25)
- Does secA mediate coupling between secretion and translation in Escherichia coli? (1986) (24)
- Regulation of the lac operon. Recent studies on the regulation of lactose metabolism in Escherichia coli support the operon model. (1967) (24)
- Positions of early nonsense and deletion mutations in lacZ (1980) (24)
- Disulfide bond formation in periplasm of Escherichia coli. (2002) (24)
- Transposition of the lac region of Escherichia coli. II. On the role of thiogalactoside transacetylase in lactose metabolism. (1966) (24)
- The XYY syndrome: a dangerous myth. (1974) (23)
- Structure and multistate function of the transmembrane electron transporter CcdA (2015) (23)
- The transmembrane domain of the DnaJ-like protein DjlA is a dimerisation domain (2003) (23)
- Evidence from Artificial Septal Targeting and Site-Directed Mutagenesis that Residues in the Extracytoplasmic β Domain of DivIB Mediate Its Interaction with the Divisomal Transpeptidase PBP 2B (2010) (22)
- BIOLOGICAL CHLORINATION. VII. STUDIES ON THE BIOSYNTHESIS OF CALDARIOMYCIN. (1963) (22)
- The Disulfide Bond Formation Pathway Is Essential for Anaerobic Growth of Escherichia coli (2017) (22)
- Gender and Math Performance: Does Biology Have Implications for Educational Policy? (1983) (22)
- A double counter-selection system for the study of null alleles of essential genes in Escherichia coli. (1995) (21)
- Use of gene fusions to determine the orientation of gene phoA on the Escherichia coli chromosome (1981) (21)
- The operon as paradigm: normal science and the beginning of biological complexity. (2011) (20)
- Genetic selection for and molecular dynamic modeling of a protein transmembrane domain multimerization motif from a random Escherichia coli genomic library. (2001) (20)
- Secretion and processing of ribose-binding protein in Escherichia coli (1982) (19)
- The Protein Translocation Apparatus Contributes to Determining the Topology of an Integral Membrane Protein in Escherichia coli * (1998) (19)
- Mutations of the Membrane-Bound Disulfide Reductase DsbD That Block Electron Transfer Steps from Cytoplasm to Periplasm in Escherichia coli (2006) (19)
- Alkaline phosphatase synthesis in a cell-free system using DNA and RNA templates. (1977) (19)
- Mutational Alterations of the Key cis Proline Residue That Cause Accumulation of Enzymatic Reaction Intermediates of DsbA, a Member of the Thioredoxin Superfamily (2005) (19)
- Isolation and characterization of mutants of Escherichia coli K12 affected in protein localization. (1983) (19)
- Structure of the malB region in Escherichia coli K12 (1979) (19)
- Repurposing lipoic acid changes electron flow in two important metabolic pathways of Escherichia coli (2011) (19)
- A genetic approach to characterizing complex promoters in E. coli (1981) (19)
- Genetic testing in the workplace: a view from the USA. (1992) (18)
- Special Supplement: The XYY Controversy: Researching Violence and Genetics (1980) (18)
- The essential cell division protein FtsN contains a critical disulfide bond in a non‐essential domain (2017) (18)
- Folding LacZ in the Periplasm of Escherichia coli (2014) (17)
- Protein export in Escherichia coli (1992) (17)
- The Bell Curve: statement by the NIH-DOE Joint Working Group on the Ethical, Legal, and Social Implications of Human Genome Research. (1996) (17)
- THE CHROMOSOMAL LOCATION OF THE STRUCTURAL GENE FOR OROTIDYLIC ACID PYROPHOSPHORYLASE IN ESCHERICHIA COLI. (1964) (17)
- Crystal Structure of an Unusual Thioredoxin Protein with a Zinc Finger Domain* (2007) (16)
- Altered Escherichia coli membrane protein assembly machinery allows proper membrane assembly of eukaryotic protein vitamin K epoxide reductase (2015) (16)
- Genetic fusions that help define a transcription termination region in Escherichia coli. (1976) (16)
- Pleiotropic mutants affecting the secretory apparatus of Escherichia coli. (1982) (15)
- The expanding world of oxidative protein folding (2001) (15)
- Blue ghosts: a new method for isolating amber mutants defective in essential genes of Escherichia coli (1981) (15)
- The reducing activity of glutaredoxin 3 toward cytoplasmic substrate proteins is restricted by methionine 43. (2007) (15)
- On the social responsibility of scientists. (2001) (14)
- Genetic evidence that the operator locus is distinct from the the z gene in the lac operon of Escherichia coli. (1969) (14)
- Redox state of cytoplasmic thioredoxin. (2002) (13)
- Position of the mutation in beta-galactosidase ochre mutant U118 (1978) (12)
- MAKING GENES, MAKING WAVES: A SOCIAL ACTIVIST IN SCIENCE (2002) (12)
- Fifty years fused to lac. (2013) (12)
- Inhibition of Pseudomonas aeruginosa and Mycobacterium tuberculosis disulfide bond forming enzymes (2019) (12)
- Inhibition of virulence-promoting disulfide bond formation enzyme DsbB is blocked by mutating residues in two distinct regions (2017) (12)
- The genetics of protein secretion in Escherichia coli. (1981) (12)
- Genetic determination of constitutive enzyme levels. (1962) (12)
- Genetic Suppressors and Recovery of Repressed Biochemical Memory (2009) (11)
- Racism: A Central Problem for the Human Genome Diversity Project (1999) (11)
- Mutations at Several Loci Cause Increased Expression of Ribonucleotide Reductase in Escherichia coli (2012) (11)
- The all purpose gene fusion. (2000) (11)
- Synthesis of D,L-Caldariomycin1 (1961) (10)
- What Lies Beyond Uranus?: Preconceptions, Ignorance, Serendipity and Suppressors in the Search for Biology's Secrets (2007) (10)
- The XYY male: the making of a myth. (1976) (9)
- The Implications of Sociobiology (1976) (9)
- Fusions of the lac and trp regions of escherichia coli: covalently fused messenger RNA. (1971) (8)
- Alkaline phosphatase fusions in the study of cell division genes. (1991) (8)
- Why teach ethics in science and engineering? (1995) (8)
- Using Dialogues to Explore Genetics, Ancestry, and Race (2017) (7)
- Harvard XYY study. (1975) (7)
- Determinants of activity in glutaredoxins: an in vitro evolved Grx1-like variant of Escherichia coli Grx3. (2010) (6)
- Strategies for finding mutants. (1991) (6)
- Identification of the Thioredoxin Partner of Vitamin K Epoxide Reductase in Mycobacterial Disulfide Bond Formation (2018) (6)
- A gene fusion method for assaying interactions of protein transmembrane segments in vivo. (2000) (6)
- Gene expression in bacteria and some concerns about the misuse of science. (1970) (6)
- Research Article 11: Deletion of Translational Start Signals in the lac Operon of E. coli (1970) (6)
- Reply to Hook and Lowden: the definition and implications of genetic discrimination. (1992) (6)
- SCIENCE FOR THE PEOPLE (1972) (6)
- The politics of genetic engineering: who decides who's defective? (1974) (6)
- Gene fusion approaches to membrane protein topology. (1993) (5)
- Commentary on “the social responsibilities of biological scientists” (S. J. Reiser and R. E. Bulger) (1997) (5)
- Essential features of the pathway for protein translocation across the Escherichia coli cytoplasmic membrane. (1995) (5)
- The use of extragenic suppressors to define genes involved in protein export in Escherichia coli (2004) (5)
- More Alarums and Excursions (1969) (4)
- Aeropyrum pernix membrane topology of protein VKOR promotes protein disulfide bond formation in two subcellular compartments. (2017) (4)
- Amino acid residues important for folding of thioredoxin are revealed only by study of the physiologically relevant reduced form of the protein. (2010) (4)
- Turkey must end violent response to protests. (2013) (4)
- ‘Race’, IQ and Genes (2006) (4)
- Behind the Mask of Objective Science (1976) (4)
- The catabolite gene activator protein (CAP) is not required for indole-3-acetic acid to activate transcription of the araBAD operon of Escherichia coli K-12 (2004) (4)
- Mechanism and applications of free radical cyclization (1986) (3)
- William Hayes: Pioneering Contributions Remembered (1995) (3)
- Simplicity and complexity: Is IQ ready for genetics? (2004) (3)
- Misreading Dr. Venter's Genome (2007) (3)
- Disulfide Bond Formation in the Periplasm and Cytoplasm of Escherichia Coli (2003) (2)
- Genetic Approaches for Studying Protein Localization (1982) (2)
- Phage display extends its reach (2006) (2)
- Genes and Human Behavior: Ethical Implications (2018) (2)
- Classical genetics and site directed mutagenesis in the study of the specific interaction with DNA of CAP, the cyclic AMP receptor protein in E. coli K 12 (1986) (1)
- Misconceptions of biometrical IQists. Commentaries. Authors' reply (1999) (1)
- Chapter 5 Steps in the assembly of a cytoplasmic membrane protein: the MalF component of the maltose transport complex (1992) (1)
- The Misunderstood Gene.By Michel Morange; translated byMatthew Cobb.Cambridge (Massachusetts): Harvard University Press. $24.95. xii + 222 p; index. ISBN: 0–674–00336–5. [Originally published asLa Part des Gènes,by Editions Odile Jacob, 1998.] 2001. (2002) (1)
- The Return of the Blue Unicorn (1997) (1)
- Letter: XYY disclosure condemned. (1975) (1)
- An active life in science (2004) (1)
- Chapter 6.1 Genes and human behavior: scientific and ethicalimplications of the human genome project (1999) (1)
- Missing Heritability: Hidden Environment in Genetic Studies of Human Behavior (2012) (1)
- Protein Translocation in the Minireview Three Domains of Life: Variations on a Theme (1997) (1)
- From Protein Folding to Blood Coagulation: Menaquinone as a Metabolic Link between Bacteria and Mammals (2017) (1)
- PBAD promoter. arabinose expression by vectors containing the Tight regulation, modulation, and high-level (2013) (1)
- The Disulfide Bond Formation Pathway Is Essential for Anaerobic Growth of Escherichia coli (2017) (1)
- Human genetic engineering: a social and political perspective. (1979) (0)
- Solution NMR structure of DsbB-ubiquinone complex (2008) (0)
- Solution NMR structure of integral membrane protein DsbB (2008) (0)
- secE encodes an integral protein required for protein export in Escherichia coli (2007) (0)
- Race, Genetics and Medicine: New Information, Enduring Questions: Final Report on Conference held on April 9, 2005 and its Sequelae (2008) (0)
- University of Groningen Contribution of the FtsQ Transmembrane Segment to Localization to the Cell Division Site Scheffers, (2012) (0)
- Clever Mutant Isolation: Defining the Components of Cell Biological Processes (2013) (0)
- Carroll SB (2013) Brave Genius: A Scientist, a Philosopher, and Their Daring Adventures from the French Resistance to the Nobel Prize. New York: Crown. 576 pp. ISBN 978-0-307-95233-2 (hardcover). US$28.00. (2013) (0)
- Chapter II: Lac: The Genetic System (1970) (0)
- Genetic Characterization of a Stable F ' lac Plasmid ' (0)
- Title : Inhibition of Pseudomonas aeruginosa and Mycobacterium tuberculosis disulfide bond forming enzymes Running Title : Targeting virulence and growth of pathogenic bacteria (2018) (0)
- The secD locus of E. coli codes for two membrane proteins required for protein export. (1990) (0)
- Integration of Specialized Transducing Bacteriophage A cI857 (0)
- Mutants of Escherichia coli Reflect the Cold Sensitivity of Protein Export Itself Kit (2002) (0)
- TRANSPOSITION OF THE LACTOSE OPERON IN « ESCHERICHIA COLI» (1966) (0)
- Crystal structure of thioredoxin-2 (2007) (0)
- A Scholarship Fund in Memory of Malcolm Casadaban (2012) (0)
- Corrigendum: Structure and multistate function of the transmembrane electron transporter CcdA (2015) (0)
- DsbC-DsbDalpha complex (2003) (0)
- Genes Found and Lost: Misperceptions of Behavioral Genetics (2000) (0)
- The use of extragenie suppressors to define genes involved in protein export in Escherichia coil (0)
- Genetics of bacterial diversity: edited by David A. Hopwood and Keith F. Chalter, Academic Press, 1989. £45.00, $89.00 (xvi + 449 pages) ISBN 0 12 355574 4 (1989) (0)
- Genetics and Human Behaviour: the Ethical Context Introduction (0)
- Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy (2009) (0)
- On the philosophical analysis of genetic essentialism. Commentary on: "The use of genetic test information in insurance: the argument from indistinguishability reconsidered". (2000) (0)
- bor Gene of Phage (cid:108) , Involved in Serum Resistance, Encodes a Widely Conserved Outer Membrane Lipoprotein (1995) (0)
- Introduction: From Physiology to DNA and Back (1996) (0)
- The Role of the Promoter Site in Gene Expression (1968) (0)
- Investigating the status of oxidative protein folding in escherichia coli missing components of the thiol-redox pathways (2008) (0)
- Criticism and realism (1987) (0)
- Bridge over Troubled Waters: Minireview Sensing Stress by Disulfide Bond Formation (1999) (0)
- Escherichia colidissection of divisome assembly in Premature targeting of a cell division protein to midcell allows data (2004) (0)
- Disulfide bond formation in prokaryotes (2018) (0)
- Characterization ofCold-Sensitive secYMutantsofEscherichia coli (1990) (0)
- Leakage of Periplasmic Enzymes by Mu tants of Escherichia coli and Salmonella typhimurium : Isolation of " Periplasmic Leaky ' Mutants (2017) (0)
- The Role of Charged Amino Acids Minireview in the Localization of Secreted and Membrane Proteins (1990) (0)
- Insurance commissioners and genetic discrimination. (1993) (0)
- GeneExpression inBacteria andSomeConcerns AbouttheMisuse ofScience (1970) (0)
- Who Was Wronged in XYY (1981) (0)
- Patents and literature (1983) (0)
- Artificial Septal Targeting of Bacillus subtilis Cell Division Proteins in Escherichia coli : an Interspecies Approach to the Study of Protein-Protein Interactions in Multiprotein Complexes (cid:1) (2008) (0)
- The Nucleotide Sequence of the Gene for maZF Protein , an Inner Membrane Component of the Maltose Transport System of Escherichia coli (0)
- A double counter-selection system for the study of null alleles of essential genes in Escherichia coli [Gene 155 (1995) 1–7] (1995) (0)
- In memoriam: Phillip J. Bassford, 1948–1991 (1992) (0)
- The thioredoxin-like domain of a VKOR homolog from Synechococcus sp. (2010) (0)
- On the philosophical analysis of genetic essentialism (2000) (0)
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