Jon Clardy
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American chemist
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Jon Clardychemistry Degrees
Chemistry
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#993
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Organic Chemistry
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#103
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Chemistry
Jon Clardy's Degrees
- Bachelors Chemistry University of California, Berkeley
- PhD Chemistry University of California, Berkeley
Why Is Jon Clardy Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jon Clardy is currently the Hsien Wu and Daisy Yen Wu professor of biological chemistry and molecular pharmacology at Harvard Medical School. His research focuses on the isolation and structural characterization of natural products, and currently investigates the role of biologically active small molecules in mediating symbiotic interactions and disease.
Jon Clardy's Published Works
Published Works
- Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products. (1998) (1661)
- Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. (2013) (1360)
- Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms (2000) (1251)
- Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. (1993) (1202)
- Lessons from natural molecules (2004) (983)
- Structure of the FKBP12-Rapamycin Complex Interacting with Binding Domain of Human FRAP (1996) (798)
- d-Amino Acids Trigger Biofilm Disassembly (2010) (734)
- Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters (2014) (677)
- Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria (1981) (673)
- Isolation and structure of bryostatin 1 (1982) (649)
- Minimum Information about a Biosynthetic Gene cluster. (2015) (600)
- New antibiotics from bacterial natural products (2006) (570)
- Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex (1991) (554)
- Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators. (2006) (549)
- Diarrhetic shellfish toxins (1985) (549)
- D-Amino Acids Govern Stationary Phase Cell Wall Remodeling in Bacteria (2009) (522)
- A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics (2014) (518)
- Isolation of Antibiotics Turbomycin A and B from a Metagenomic Library of Soil Microbial DNA (2002) (488)
- Tyrosol is a quorum-sensing molecule in Candida albicans. (2004) (467)
- Bacterial Protection of Beetle-Fungus Mutualism (2008) (436)
- GABA Modulating Bacteria of the Human Gut Microbiota (2018) (419)
- Sexual attraction in the silkworm moth: structure of the pheromone-binding-protein-bombykol complex. (2000) (413)
- Isolation and structure of brevetoxin B from the "red tide" dinoflagellate Ptychodiscus brevis (Gymnodinium breve) (1981) (409)
- Siderophores from neighboring organisms promote the growth of uncultured bacteria. (2010) (396)
- Structure of human methionine aminopeptidase-2 complexed with fumagillin. (1998) (393)
- Target identification using drug affinity responsive target stability (DARTS) (2009) (383)
- Biological activities of two fungistatic antibiotics produced by Bacillus cereus UW85 (1994) (375)
- Crystal and molecular structure of dynemicin A: a novel 1,5-diyn-3-ene antitumor antibiotic (1990) (355)
- Target identification using drug affinity responsive target stability (DARTS). (2009) (348)
- The Jekyll-and-Hyde chemistry of Phaeobacter gallaeciensis. (2011) (346)
- Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis. (2009) (345)
- A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. (2003) (336)
- A Hub-and-Spoke Circuit Drives Pheromone Attraction and Social Behavior in C. elegans (2009) (328)
- Castanospermine, A 1,6,7,8-tetrahydroxyoctahydroindolizine alkaloid, from seeds of Castanospermum australe (1981) (326)
- Small-molecule pheromones that control dauer development in Caenorhabditis elegans. (2007) (326)
- Pestalone, a new antibiotic produced by a marine fungus in response to bacterial challenge. (2001) (321)
- Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn’s disease, produces an inflammatory polysaccharide (2019) (309)
- A huband-spoke circuit drives pheromone attraction and social behaviour in C . elegans (2009) (289)
- Lassomycin, a ribosomally synthesized cyclic peptide, kills mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2. (2014) (278)
- Rearranged hopanes in sediments and petroleum (1991) (272)
- Diarrhetic Shellfish Poisoning (1984) (271)
- The natural history of antibiotics (2009) (271)
- Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity (2002) (268)
- Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents. (2000) (252)
- The evolution of gene collectives: How natural selection drives chemical innovation (2008) (249)
- Isolation and Structure Determination of Diazonamides A and B, Unusual Cytotoxic Metabolites from the Marine Ascidian Diazona chinensis (1991) (247)
- Jaspamide, a modified peptide from a Jaspis sponge, with insecticidal and antifungal activity. (1986) (243)
- Metabolites of the marine prosobranch mollusk Lamellaria sp (1985) (234)
- Structure of brevetoxin A (GB-1 toxin), the most potent toxin in the Florida red tide organism Gymnodinium breve (Ptychodiscus brevis). (1986) (233)
- The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis (2007) (233)
- Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes (2003) (232)
- Total synthesis of the macrolide antibiotic cytovaricin (1990) (231)
- Dynemicin A, a novel antibiotic with the anthraquinone and 1,5-diyn-3-ene subunit. (1989) (229)
- Structure of saxitoxin (1975) (217)
- Esperamicins, a novel class of potent antitumor antibiotics. 2. Structure of esperamicin X (1987) (212)
- Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum (2017) (208)
- A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals (2012) (205)
- Production of kanosamine by Bacillus cereus UW85 (1996) (201)
- Cyclomarins A−C, New Antiinflammatory Cyclic Peptides Produced by a Marine Bacterium (Streptomyces sp.) (1999) (199)
- Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP (1998) (199)
- Production of α-Galactosylceramide by a Prominent Member of the Human Gut Microbiota (2013) (197)
- Scytophycins, cytotoxic and antimycotic agents from the cyanophyte Scytonema pseudohofmanni (1986) (196)
- Two Chemoreceptors Mediate Developmental Effects of Dauer Pheromone in C. elegans (2009) (196)
- Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA. (2001) (196)
- Diversity-oriented synthesis yields novel multistage antimalarial inhibitors (2016) (190)
- A Bacillus subtilis sensor kinase involved in triggering biofilm formation on the roots of tomato plants (2012) (188)
- Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria (2010) (177)
- Sceptrin, an antimicrobial agent from the sponge Agelas sceptrum (1981) (176)
- Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin (2009) (175)
- ATOMIC-STRUCTURE OF THE BURIED CATALYTIC POCKET OF ESCHERICHIA-COLI CHORISMATE MUTASE. (1995) (175)
- DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12. (1994) (173)
- The pseudopterosins: anti-inflammatory and analgesic natural products from the sea whip Pseudopterogorgia elisabethae. (1986) (172)
- Vinylogous polypeptides: an alternative peptide backbone (1992) (170)
- High-Throughput Plasmodium falciparum Growth Assay for Malaria Drug Discovery (2006) (169)
- Torreyanic Acid: A Selectively Cytotoxic Quinone Dimer from the Endophytic Fungus Pestalotiopsis microspora (1996) (167)
- One pathway, many products. (2007) (167)
- Cryptocin, a potent tetramic acid antimycotic from the endophytic fungus Cryptosporiopsis cf. quercina. (2000) (165)
- Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases (2017) (162)
- Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine (2016) (160)
- Structure of the PIN/LC8 dimer with a bound peptide (1999) (158)
- New natural product families from an environmental DNA (eDNA) gene cluster. (2002) (158)
- Structural basis of m7GpppG binding to the nuclear cap-binding protein complex (2002) (157)
- The cytosporones, new octaketide antibiotics isolated from an endophytic fungus. (2000) (157)
- Nigellidine — A new indazole alkaloid from the seeds of Nigella sativa (1995) (155)
- Biosynthesis of the Caenorhabditis elegans dauer pheromone (2009) (153)
- Isolation and structure of rebeccamycin - a new antitumor antibiotic from nocardia aerocoligenes (1985) (152)
- The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis. (2000) (152)
- A potent dauer pheromone component in Caenorhabditis elegans that acts synergistically with other components (2008) (149)
- Trichodermamides A and B, cytotoxic modified dipeptides from the marine-derived fungus Trichoderma virens. (2003) (148)
- Dicerandrols, new antibiotic and cytotoxic dimers produced by the fungus Phomopsis longicolla isolated from an endangered mint. (2001) (147)
- Long-Chain N-Acyl Amino Acid Antibiotics Isolated from Heterologously Expressed Environmental DNA (2000) (147)
- Subglutinols A and B: Immunosuppressive compounds from the endophytic fungus Fusarium subglutinans (1995) (145)
- Dysidiolide: A Novel Protein Phosphatase Inhibitor from the Caribbean Sponge Dysidea etheria de Laubenfels (1996) (143)
- Heavy metal and pesticide content in commonly prescribed individual raw Chinese Herbal Medicines. (2011) (142)
- Fascaplysin, an unusual antimicrobial pigment from the marine sponge Fascaplysinopsis sp (1988) (141)
- The pseudopterosins: a new class of antiinflammatory and analgesic diterpene pentosides from the marine sea whip Pseudopterogorgia elisabethae (Octocorallia) (1986) (141)
- Interspecies modulation of bacterial development through iron competition and siderophore piracy (2012) (139)
- Dynamic metabolic exchange governs a marine algal-bacterial interaction (2016) (138)
- Bisandrographolide from Andrographis paniculata Activates TRPV4 Channels* (2006) (137)
- Mycangimycin, a Polyene Peroxide from a Mutualist Streptomyces sp. (2009) (137)
- A pentahalogenated monoterpene from the red alga Portieria hornemannii produces a novel cytotoxicity profile against a diverse panel of human tumor cell lines. (1992) (137)
- Small molecule perimeter defense in entomopathogenic bacteria (2012) (137)
- Antileukemic alkaloids from Taxus wallichiana Zucc (1981) (136)
- Korupensamines A-D, Novel Antimalarial Alkaloids from Ancistrocladus korupensis (1994) (136)
- High-Throughput Screens for Small-Molecule Inhibitors of Pseudomonas aeruginosa Biofilm Development (2007) (135)
- Using the heat-shock response to discover anticancer compounds that target protein homeostasis. (2011) (134)
- Bacterial symbionts and natural products. (2011) (132)
- The guanacastepenes: a highly diverse family of secondary metabolites produced by an endophytic fungus. (2001) (132)
- Atomic Structure of the Rapamycin Human Immunophilin FKBP-12 Complex (1991) (132)
- Guanacastepene, a fungal-derived diterpene antibiotic with a new carbon skeleton (2000) (131)
- Three new cytochalasins produced by an endophytic fungus in the genus Rhinocladiella. (2000) (131)
- Liver-stage malaria parasites vulnerable to diverse chemical scaffolds (2012) (124)
- Isolation and structure determination of nigellicine, a novel alkaloid from the seeds of (1985) (123)
- Chemical Analyses of Wasp-Associated Streptomyces Bacteria Reveal a Prolific Potential for Natural Products Discovery (2011) (122)
- Some metabolites of the marine sponges Smenospongia aurea and Smenospongia (.ident.Polyfibrospongia) echina (1980) (122)
- New alkaloids of the lamellarin class from the marine ascidian Didemnum chartaceum (Sluiter, 1909) (1988) (121)
- .eta.5-Cyclohexadienyltricarbonylchromium(0) complexes from addition of carbon nucleophiles to .eta.6-benzenetricarbonylchromium(0). Formation, chemical and spectroscopic features, and x-ray diffraction analysis (1979) (120)
- FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells (2008) (119)
- Transannular Diels-Alder route to systems related to dynemicin A (1990) (119)
- Mycotoxins produced by Aspergillus fumigatus species isolated from molded silage. (1977) (118)
- New anti-inflammatory pseudopterosins from the marine octocoral Pseudopterogorgia elisabethae (1990) (118)
- Synthesis and Activity of Biomimetic Biofilm Disruptors (2013) (117)
- Asymmetric synthesis of chiral organosulfur compounds using N-sulfinyloxazolidinones (1992) (117)
- Roseobacticides: Small Molecule Modulators of an Algal-Bacterial Symbiosis (2011) (116)
- Structure proof and significance of stereoisomeric 28,30-bisnorhopanes in petroleum and petroleum source rocks (1984) (116)
- Absolute stereochemistries of the aplysiatoxins and oscillatoxin A (1984) (114)
- Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. (1999) (113)
- A biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid. (2006) (111)
- 9-Isocyanopupukeanane, a marine invertebrate allomone with a new sesquiterpene skeleton (1975) (110)
- Ilimaquinone, a sesquiterpenoid quinone from a marine sponge (1979) (110)
- Bacterial printing press that regenerates its ink: contact-printing bacteria using hydrogel stamps. (2005) (108)
- Citral Sensing by TRANSient Receptor Potential Channels in Dorsal Root Ganglion Neurons (2008) (108)
- Quorum-Sensing-Regulated Bactobolin Production by Burkholderia thailandensis E264 (2010) (108)
- Total synthesis of carpanone (1971) (105)
- Crystal and solution structures of an odorant-binding protein from the southern house mosquito complexed with an oviposition pheromone (2010) (105)
- A self-produced trigger for biofilm disassembly that targets exopolysaccharide. (2012) (105)
- Antifungal diterpenoid alkaloids from Delphinium denudatum. (1997) (104)
- Pseudopterolide, an irregular diterpenoid with unusual cytotoxic properties from the Caribbean sea whip Pseudopterogorgia acerosa (Pallas) (Gorgonacea) (1982) (104)
- Cloning and heterologous expression of isocyanide biosynthetic genes from environmental DNA. (2005) (103)
- Isolation and structural proof of the large diamond molecule, cyclohexamantane (C26H30). (2003) (101)
- Long-Chain N-Acyltyrosine Synthases from Environmental DNA (2004) (100)
- The structures of syringolides 1 and 2, novel C-glycosidic elicitors from Pseudomonas syringae pv. tomato (1993) (100)
- Regulating Alternative Lifestyles in Entomopathogenic Bacteria (2010) (99)
- Salinamides A and B: anti-inflammatory depsipeptides from a marine streptomycete (1994) (99)
- Pyridoacridine alkaloids from deep-water marine sponges of the family Pachastrellidae: structure revision of dercitin and related compounds and correlation with the kuanoniamines (1992) (97)
- Progestins activate the AKT pathway in leiomyoma cells and promote survival. (2009) (97)
- A Single Promoter Inversion Switches Photorhabdus Between Pathogenic and Mutualistic States (2012) (97)
- Microtermolides A and B from Termite-Associated Streptomyces sp. and Structural Revision of Vinylamycin (2012) (94)
- Unequivocal determination of complex molecular structures using anisotropic NMR measurements (2017) (94)
- Enantioselective Michael Reactions. Diastereoselective Reactions of Chlorotitanium Enolates of Chiral N- Acyloxazolidinones with Representative Electrophilic Olefins (1991) (93)
- FOXO3a Is Broadly Neuroprotective In Vitro and In Vivo against Insults Implicated in Motor Neuron Diseases (2009) (93)
- Structure and absolute configuration of malyngolide, an antibiotic from the marine blue-green alga Lyngbya majuscula Gomont (1980) (92)
- A fungal endophyte-tree relationship: Phoma sp. in Taxus wallachiana (1994) (92)
- Structure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor. (2006) (92)
- Octalactins A and B, cytotoxic eight membered ring lactones from a marine bacterium Streptomyces sp. (1991) (91)
- Pestalotiopsins A and B: New Caryophyllenes from an Endophytic Fungus of Taxus brevifolia (1996) (90)
- Bacterial lipids activate, synergize, and inhibit a developmental switch in choanoflagellates (2016) (90)
- New insight into the catalytic mechanism of chorismate mutases from structural studies. (1995) (89)
- Hormothamnione, a novel cytotoxic styrylchromone from the marine cyanophyte grunow (1986) (89)
- Zwittermicin A, an antifungal and plant protection agent from Bacillus cereus (1994) (89)
- Coil-to-helix transition and ligand release of Bombyx mori pheromone-binding protein. (2005) (88)
- Defense contracts: molecular protection in insect-microbe symbioses. (2018) (88)
- CR377, a new pentaketide antifungal agent isolated from an endophytic fungus. (2000) (88)
- Catecholate Siderophores Protect Bacteria from Pyochelin Toxicity (2012) (87)
- Olfactory Plasticity Is Regulated by Pheromonal Signaling in Caenorhabditis elegans (2010) (86)
- Macrotermycins A-D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39. (2017) (86)
- Zoanthamine : a novel alkaloid from a marine zoanthid (1984) (85)
- Isolation and structure/activity features of halomon-related antitumor monoterpenes from the red alga Portieria hornemannii. (1994) (85)
- Defense Allomones of the Nudibranch Phyllidia varicosa Lamarck 1801 (1979) (83)
- Halenaquinone, a pentacyclic polyketide from a marine sponge (1983) (83)
- The chemistry of signal transduction. (1995) (83)
- Structure and Biosynthesis of Amychelin, an Unusual Mixed-Ligand Siderophore from Amycolatopsis sp. AA4 (2011) (83)
- Mating in the Closest Living Relatives of Animals Is Induced by a Bacterial Chondroitinase (2017) (83)
- Unusual C25 steroids produced by a sponge-derived Penicillium citrinum. (2003) (83)
- The relationship between an endangered North American tree and an endophytic fungus. (1995) (82)
- RETRACTED: A Self-Produced Trigger for Biofilm Disassembly that Targets Exopolysaccharide (2012) (81)
- Sceliphrolactam, a Polyene Macrocyclic Lactam from a Wasp-Associated Streptomyces sp. (2011) (81)
- Psychrotrophic strain of Janthinobacterium lividum from a cold Alaskan soil produces prodigiosin. (2010) (81)
- Biological activity of guanacastepene, a novel diterpenoid antibiotic produced by an unidentified fungus CR115. (2000) (81)
- Structure and biosynthesis of borophycin, a new Boeseken complex of boric acid from a marine strain of the blue-green alga Nostoc linckia (1994) (81)
- Kallolide A, a new antiinflammatory diterpenoid, and related lactones from the Caribbean octocoral Pseudopterogorgia kallos (Bielschowsky) (1985) (80)
- Bombyx mori pheromone-binding protein binding nonpheromone ligands: implications for pheromone recognition. (2007) (80)
- Identification and Characterization of Small Molecule Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase* (2008) (80)
- Two synthetic approaches to rebeccamycin (1985) (80)
- Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum (2009) (79)
- Nigellidine ‐ A New Indazole Alkaloid from the Seeds of Nigella sativa. (1995) (79)
- Structure and synthesis of moniliformin, a novel cyclobutane microbial toxin. (1974) (78)
- Selvamicin, an atypical antifungal polyene from two alternative genomic contexts (2016) (78)
- Antibiotic and Antimalarial Quinones from Fungus-Growing Ant-Associated Pseudonocardia sp. (2012) (77)
- Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. (2003) (77)
- THE STRUCTURE OF SAXITOXIN (1975) (76)
- Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways (2020) (75)
- Structures of dictyodial and dictyolactone, unusual marine diterpenoids (1979) (75)
- Derivatives of 1-methoxy-3-trimethylsilyloxy-1,3-butadiene for Diels-Alder reactions (1979) (75)
- Letter: Structure of verruculogen, a tremor producing peroxide from Penicillium verruculosum. (1974) (75)
- Chorismate Mutase-Prephenate Dehydratase from Escherichia coli (1998) (74)
- Variable genetic architectures produce virtually identical molecules in bacterial symbionts of fungus-growing ants (2015) (74)
- Cyclomarins A—C, New Antiinflammatory Cyclic Peptides Produced by a Marine Bacterium (Streptomyces sp.). (2000) (73)
- Isolation and structural elucidation of an antioxidative agent, naphterpin. (1990) (73)
- Berkeleydione and berkeleytrione, new bioactive metabolites from an acid mine organism. (2004) (73)
- Prianosin A, a novel antileukemic alkaloid from the okinawan marine sponge Prianos melanos (1987) (73)
- Absolute stereochemistry and dopaminergic activity of enantiomers of 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine. (1982) (72)
- Homodimericin A: A Complex Hexacyclic Fungal Metabolite (2016) (72)
- Natalamycin A, an Ansamycin from a Termite-Associated Streptomyces sp. (2014) (72)
- An indole-containing dauer pheromone component with unusual dauer inhibitory activity at higher concentrations. (2009) (71)
- Recent research in marine natural products: the puupehenones (1979) (70)
- Palmitoylputrescine, an antibiotic isolated from the heterologous expression of DNA extracted from bromeliad tank water. (2004) (70)
- Bacterial symbionts in agricultural systems provide a strategic source for antibiotic discovery (2013) (68)
- Isolation and structure determination of four novel diterpenes from jatropha curcus (1986) (67)
- Structures of novel anthracycline antitumor antibiotics from Micromonospora peucetica (1980) (67)
- The Next Opportunity in Anti-Malaria Drug Discovery: The Liver Stage (2011) (67)
- Reactions of Group 6 Fischer carbene complexes with alkynes: effect of the metal on the product distribution and the isolation of a nontautomerized cyclohexadienone complex (1994) (66)
- Stingless Bee Larvae Require Fungal Steroid to Pupate (2018) (66)
- Letter: Tryptoquivaline and tryptoquivalone, two tremorgenic metabolites of aspergillus clavatus. (1975) (66)
- Kalihinol-A, a highly functionalized diisocyano diterpenoid antibiotic from a sponge (1984) (65)
- The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs (2015) (65)
- Letter: A novel diterpene from Dollabella californica. (1976) (65)
- [7.7]Paracyclophanes from blue-green algae (1990) (64)
- Nostoclide I and II, extracellular metabolites from a symbiotic cyanobacterium, Nostoc sp., from the lichen Peltigera canina. (1993) (64)
- Antitumor agents from Streptomyces anandii: gilvocarcins V, M and E. (1981) (64)
- Letter: structure of cytochalasin E, a toxic metabolite of Aspergillus clavatus. (1973) (64)
- Cellulolytic Streptomyces Strains Associated with Herbivorous Insects Share a Phylogenetically Linked Capacity To Degrade Lignocellulose (2014) (64)
- Majusculamides A and B, two epimeric lipodipeptides from Lyngbya majuscula Gomont (1977) (63)
- Phytotoxins from the pathogenic fungi Drechslera maydis and Drechslera sorghicola. (1987) (63)
- De-O-methyldiaporthin, a phytotoxin from Drechslera siccans (1988) (62)
- Codinaeopsin, an antimalarial fungal polyketide. (2008) (62)
- 2,4-Methanoproline (2-carboxy-2,4-methanopyrrolidine) and 2,4-methanoglutamic acid (1-amino-1,3-dicarboxycyclobutane) in seeds of Ateleia herbert smithii Pittier (Leguminosae) (1980) (62)
- Phaeosphaeride A, an inhibitor of STAT3-dependent signaling isolated from an endophytic fungus. (2006) (62)
- HIV inhibitory natural products. 3. Diterpenes from and (1991) (62)
- Haliclonadiamine, an antimicrobial alkaloid from the sponge Haliclona sp. (1988) (62)
- Convergent evolution of complex structures for ant–bacterial defensive symbiosis in fungus-farming ants (2018) (61)
- Structure of the psammaplysins (1985) (60)
- Bipolaroxin, a selective phytotoxin produced by Bipolaris cynodontis. (1985) (60)
- Structures of the efrapeptins : potent inhibitors of mitochondrial ATPase from the fungus Tolypocladium niveum (1991) (60)
- Targeted discovery of polycyclic tetramate macrolactams from an environmental Streptomyces strain. (2010) (60)
- A bacterial symbiont is converted from an inedible producer of beneficial molecules into food by a single mutation in the gacA gene (2013) (59)
- Transglutaminase 5 is regulated by guanine-adenine nucleotides. (2004) (59)
- Subglutinols A and B: Immunosuppressive Compounds from the Endophytic Fungus Fusarium subglutinans. (1996) (58)
- Two imidazole alkaloids from a sponge (1990) (58)
- An antimalarial peroxide from Amomum krervanh Pierre (1995) (58)
- The structure of paxilline, a tremorgenic metabolite of bainier (1975) (58)
- Differential analysis of 2D NMR spectra: new natural products from a pilot-scale fungal extract library. (2007) (58)
- Isolation and structure of spatol, a potent inhibitor of cell replication from the brown seaweed Spatoglossum schmittii (1980) (58)
- Quinones are growth factors for the human gut microbiota (2017) (58)
- Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors. (2009) (58)
- Nitrogenous bisabolene sesquiterpenes from marine invertebrates (1986) (58)
- Hybrid Biosynthesis of Roseobacticides from Algal and Bacterial Precursor Molecules (2014) (57)
- Producing selenomethionine-labeled proteins with a baculovirus expression vector system. (1999) (56)
- Additions and Corrections - Sex Pheromone of the American Cockroach: Absolute Configuration of Periplanone-B (1979) (56)
- Chain-folding initiation structures in ribonuclease A: conformational analysis of trans-Ac-Asn-Pro-Tyr-NHMe and trans-Ac-Tyr-Pro-Asn-NHMe in water and in the solid state (1984) (56)
- Exploiting a global regulator for small molecule discovery in Photorhabdus luminescens. (2010) (56)
- Discovery of a novel pharmacological and structural class of gamma secretase modulators derived from the extract of Actaea racemosa. (2012) (56)
- [3.3]metacyclophane: a novel synthesis and a study of the structure through X-ray diffraction, molecular mechanics, and solution NMR analysis (1985) (56)
- The Structures of Amphidinolide B Isomers: Strongly Cytotoxic Macrolides Produced by a Free-Swimming Dinoflagellate, Amphidinium sp (1994) (56)
- New polychlorinated amino acid derivatives from the marine sponge Dysidea herbacea (1993) (55)
- Brasilenyne and cis-dihydrorhodophytin: Antifeedant medium-ring haloethers from a sea hare (Aplysia brasiliana). (1979) (55)
- Austin, a novel polyisoprenoid mycotoxin from Aspergillus ustus. (1976) (55)
- Atomic structure of the trypsin-A90720A complex: a unified approach to structure and function. (1994) (55)
- Cytoskyrins A and B, new BIA active bisanthraquinones isolated from an endophytic fungus. (2000) (55)
- Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen (2018) (55)
- NRPS Substrate Promiscuity Diversifies the Xenematides (2011) (55)
- Letter: A revised structure of vermiculine. A novel macrolide dilactone antibiotic from Penicillium vermiculatum. (1974) (54)
- Didemnimides A−D: Novel, Predator-Deterrent Alkaloids from the Caribbean Mangrove Ascidian Didemnum conchyliatum (1997) (54)
- Solid-state and solution studies of lithiated 2-carbomethoxycyclohexanone dimethylhydrazone and lithiated cyclohexanone phenylimine (1986) (54)
- Tawicyclamides A and B, new cyclic peptides from the Ascidian Lissoclinum patella: studies on the solution- and solid-state conformations (1992) (54)
- Structural and functional analysis of pantocin A: an antibiotic from Pantoea agglomerans discovered by heterologous expression of cloned genes. (2003) (54)
- Paspalinine, a tremorgenic metabolite from Claviceps paspali Stevens et Hall. (1980) (54)
- Three new rearranged spongian diterpenes from chromodoris macfarland: reappraisal of the structures of dendrillolides A and B (1986) (53)
- The psammaplysenes, specific inhibitors of FOXO1a nuclear export. (2005) (53)
- An unprecedented triisocyano diterpenoid antibiotic from a sponge (1984) (53)
- Sesbanimide, a potent antitumor substance from Sesbania drummondii seed (1983) (53)
- Crystal and molecular structure of BBM-928 A, a novel antitumor antibiotic from Actinomadura luzonensis (1981) (53)
- Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis. (2015) (53)
- Analysis of rapidly synthesized guest-filled porous complexes with synchrotron radiation: practical guidelines for the crystalline sponge method (2015) (52)
- Paspaline and paspalicine, two indole-mevalonate metabolites from Claviceps paspali. (1980) (52)
- New Chlorophyll-A-Related Compounds Isolated as Antioxidants from Marine Bivalves (1993) (51)
- Akanthomycin, a new antibiotic pyridone from the entomopathogenic fungus Akanthomyces gracilis. (2002) (51)
- A sesquiterpene thiocyanate and three sesquiterpene isothiocyanates from the sponge Trachyopsis aplysinoides (1989) (51)
- Subergorgic acid, a novel tricyclopentanoid cardiotoxin from the pacific gorgonian coral (1985) (51)
- Acetoxydehydroaustin, a New Bioactive Compound, and Related Compound Neoaustin from Penicillium sp. MG–11 (1994) (51)
- Chloroacetylenes as Michael acceptors. III: Mechanism and synthetic utilityof enolate reactions with halogenated olefins and chloroacetylenes (1984) (51)
- Structures and cytotoxic properties of sponge-derived bisannulated acridines. (2002) (51)
- Photochemical transormations. XXXVIII. Nonoxidative photocyclization of N-aryl enamines. A facile synthetic entry to trans-hexahydrocarbazoles (1971) (51)
- Cembrane and pseudopterane diterpenes from the soft coral Gersemia rubiformis (1987) (50)
- Antifungal Diketopiperazines from Symbiotic Fungus of Fungus-Growing Ant Cyphomyrmex minutus (2004) (50)
- Pentacyclo[12.2.2.22,5.26,9.210,13]-1,5,9,13-tetracosatetraene and its reaction with silver trifluoromethanesulfonate. Synthesis of a square-planar d10 organometallic complex. (1986) (50)
- Asymmetric Michael additions of ester enolates to enantiomerically pure vinylic sulfoxides: synthesis of 3-substituted glutarate esters in high enantiomeric purity (1986) (50)
- Clavepictines A and B: Cytotoxic Quinolizidines from the Tunicate Clavelina picta (1991) (50)
- The baconipyrones: novel polypropionates from the pulmonate Siphonaria baconi (1989) (50)
- Application of the allylic diazene rearrangement: synthesis of the enediyne-bridged tricyclic core of dynemicin A (1992) (49)
- A chimeric siderophore halts swarming Vibrio. (2014) (49)
- Viridoxins A and B: novel toxins from the fungus Metarhizium flavoviride (1993) (49)
- Aflatrem, a tremorgenic toxin from Aspergillus flavus (1980) (48)
- Plakinidines: Cytotoxic alkaloid pigments from the fijian sponge plakortis sp. (1990) (48)
- Total synthesis of 3(S)-carboxy-4(S)-hydroxy-2,3,4,5-tetrahydropyridazine, an unusual amino acid constituent of luzopeptin A (1989) (48)
- Structure of Efrapeptins From the Fungus Tolypocladium Niveum: Peptide Inhibitors of Mitochondrial ATPase (1992) (48)
- Norrisolide, a novel diterpene from the dorid nudibranch Chromodoris norrisi (1983) (48)
- Structural Basis for the Insensitivity of a Serine Enzyme (Palmitoyl-Protein Thioesterase) to Phenylmethylsulfonyl Fluoride* (2000) (48)
- Stypotriol and stypoldione; ichthyotoxins of mixed biogenesis from the marine alga ☆ (1979) (48)
- Crystal Structure of the N-terminal Segment of Human Eukaryotic Translation Initiation Factor 2α* (2002) (48)
- Metabolites of the burrowing sponge Siphonodictyon coralliphagum (1986) (47)
- Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering (2019) (47)
- Non-terpenoid C-15 metabolites from the red seaweed Laurencia pinnatifida (1982) (47)
- Metabolites of the nudibranch Chromodoris funerea and the singlet oxygen oxidation products of furodysin and furodysinin (1986) (47)
- Unprecedented constituents of a new species of acorn worm (1987) (47)
- N-acyl derivatives of arginine and tryptophan isolated from environmental DNA expressed in Escherichia coli. (2005) (47)
- The structure of leptosphaerin (1986) (47)
- The asbestinins, a novel class of diterpenes from the gorgonian Briareum asbestinum (1980) (46)
- Three new vinyl acetylenes from the marine red alga laurencia (1980) (46)
- Developing a library of authenticated Traditional Chinese Medicinal (TCM) plants for systematic biological evaluation--rationale, methods and preliminary results from a Sino-American collaboration. (2011) (46)
- Novel metabolites of four Siphonaria species (1984) (46)
- The diterpenes of Dictyota dichotoma from the Indian Ocean (1986) (46)
- Phytotoxins from Alternaria cassiae (1989) (46)
- Isolation and structure determination of the didemnenones, novel cytotoxic metabolites from tunicates (1988) (46)
- Pyrazines from bacteria and ants: convergent chemistry within an ecological niche (2018) (46)
- Structures of stemodin and stemodinone (1973) (46)
- Aphanorphine, a novel tricyclic alkaloid from the blue-green algaAphanizomenon flos-aquae (1988) (46)
- Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors. (2011) (46)
- Discorhabdin P, a new enzyme inhibitor from a deep-water Caribbean sponge of the genus Batzella. (1999) (45)
- Shermilamine A: A Pentacyclic Alkaloid from a Tunicate (1988) (45)
- The crystalline sponge method: MOF terminal ligand effects (2015) (45)
- Old meets new: using interspecies interactions to detect secondary metabolite production in actinomycetes. (2012) (45)
- Atomic Structure of the Trypsin-Aeruginosin 98-B Complex (1998) (45)
- Chiral resolution and stereospecificity of 6-phenyl-4-phenylethynyl- 1,4-dihydropyridines as selective A(3) adenosine receptor antagonists. (1999) (45)
- A New Isodrimeninol from Pestalotiopsis sp. (1996) (44)
- A triterpenoid pigment with the isomalabaricane skeleton from the marine sponge . (1982) (44)
- The Crystal Structure of Palmitoyl Protein Thioesterase-2 (PPT2) Reveals the Basis for Divergent Substrate Specificities of the Two Lysosomal Thioesterases, PPT1 and PPT2* (2003) (44)
- The structure of methyl isosartortuoate, a novel tetracyclic tetraterpenoid from the soft coral Sarcophyton tortuosum (1986) (44)
- High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity. (2007) (44)
- Ambewelamides A and B, Antineoplastic Epidithiapiperazinediones Isolated from the Lichen Usnea sp. (1998) (43)
- Diterpenoid isocyanides from the marine sponge hymeniacidon amphilecta (1978) (43)
- Total Synthesis of (+)-Octalactins A and B: Unusual Metabolites from a Marine Microbe (1994) (43)
- Chain reversals in model peptides: studies of cystine-containing cyclic peptides. 3. Conformational free energies of cyclization of tetrapeptides of sequence Ac-Cys-Pro-X-Cys-NHMe (1987) (43)
- ERYTHROLIDES: UNIQUE MARINE DITERPENOIDS INTERRELATED BY A NATURALLY OCCURRING DI-Π-METHANE REARRANGEMENT (1984) (43)
- (6R,7S)-7-amino-7,8-dihydro-.alpha.-bisabolene, an antimicrobial metabolite from the marine sponge Halichondria sp (1986) (43)
- Systematic investigation of the Escherichia coli metabolome for the biosynthetic origin of an isocyanide carbon atom. (2005) (43)
- A chemical study of cyclic depsipeptides produced by a sponge-derived fungus. (2006) (43)
- A common bacterial metabolite elicits prion-based bypass of glucose repression (2016) (42)
- A further study of the cytotoxic constituents of a milnamide-producing sponge. (2004) (42)
- Studies on the solution- and solid-state structure of patellin 2 (1990) (42)
- Atomic Structure of the Trypsin-Cyclotheonamide a Complex: Lessons for the Design of Serine Protease Inhibitors (1993) (42)
- Norcembrene diterpenoids from pacific soft-corals of the genus sinularia (Alcyonacea; octocorallia) (1985) (42)
- Zoanthaminone, a new alkaloid from a marine zoanthid (1989) (41)
- Metabolites of the Palauan sponge dactylospongia sp. (1989) (41)
- Kalihinene and isokalihinol B, cytotoxic diterpene isonitriles from the marine sponge Acanthella klethra (1990) (41)
- Stereocontrolled functionalization in the cyclohexane ring using organomolybdenum chemistry (1985) (41)
- Crystal Structure of P13K SH3 Domain at 2.0 Å Resolution (1996) (41)
- Cubitene: an irregular twelve-membered-ring diterpene from a termite soldier (1978) (41)
- Asterogynins: Secondary Metabolites from a Costa Rican Endophytic Fungus (2010) (41)
- The denticulatins, two polypropionate metabolites from the pulmonate Siphonaria denticulata (1983) (41)
- The structure of ditryptophenaline - a new metabolite of (1977) (40)
- Structure and absolute configuration of strictamine and strictalamine from Rhazya stricta. Stereochemistry of the Picralima alkaloids (1977) (40)
- Phytotoxins as potential herbicides (1991) (40)
- Chemical transformations of qinghaosu, a peroxidic antimalarial (1983) (40)
- Chloriolins A-C, Chlorinated Sesquiterpenes Produced by Fungal Cultures Separated from a Jaspis Marine Sponge (1994) (39)
- New terpenoid metabolites from the skin extracts, an egg mass, and dietary sponges of the Northeastern Pacific dorid nudibranch Cadlinaluteomarginata (1997) (39)
- New humantenine-type alkaloids from Gelsemium elegans. (1989) (39)
- The ATP-dependent amide ligases DdaG and DdaF assemble the fumaramoyl-dipeptide scaffold of the dapdiamide antibiotics. (2009) (39)
- A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity (2012) (39)
- The crystal structure of pyroglutamyl peptidase I from Bacillus amyloliquefaciens reveals a new structure for a cysteine protease. (1999) (38)
- Correction: Citral Sensing by Transient Receptor Potential Channels in Dorsal Root Ganglion Neurons (2008) (38)
- Compounds that select against the tetracycline resistance efflux pump (2016) (38)
- Sources of Diversity in Bactobolin Biosynthesis by Burkholderia thailandensis E264 (2011) (38)
- The structure of benthocyanin A. A new free radical scavenger of microbial origin (1991) (38)
- Effect of Canavanine from Alfalfa Seeds on the Population Biology of Bacillus cereus (1998) (38)
- Dictyoxetane, a novel diterpene from the brown alga Dictyota dichotoma from the Indian Ocean (1985) (38)
- Some new phytotoxic ophiobolins produced by Drechslera oryzae (1988) (38)
- Mixing and Matching Siderophore Clusters: Structure and Biosynthesis of Serratiochelins from Serratia sp. V4 (2012) (37)
- Platinum(II) complex containing a metallodithiocarboxylate ligand (1975) (37)
- The structure and biological activity of cercosporamide from Cercosporidium henningsii (1991) (37)
- HELIXANES. THE FIRST PRIMARY HELICAL MOLECULES: POLYOXAPOLYSPIROALKANONES (1980) (37)
- Identification of Anziaic Acid, a Lichen Depside from Hypotrachyna sp., as a New Topoisomerase Poison Inhibitor (2013) (37)
- Oppositol, a brominated sesquiterpene alcohol of a new skeletal class from the red alga, Laurencia subopposita. (1973) (37)
- Kalmanol, a pharmacologically active diterpenoid with a new ring skeleton from Kalmia angustifolia L (1989) (37)
- Akkermansia muciniphila phospholipid induces homeostatic immune responses (2022) (37)
- A Rebeccamycin Analog Provides Plasmid-Encoded Niche Defense. (2015) (37)
- Structure of Trigonostemone, a New Phenanthrenone from the Thai Plant Trigonostemon reidioides (1990) (37)
- The structure of a new nucleoside antibiotic, capuramycin (1988) (36)
- An elusive electron shuttle from a facultative anaerobe (2019) (36)
- Peri-bridged naphthalenes. 2. Unsymmetrical diatomic chalcogen bridges (1977) (36)
- A new imidazole alkaloid from the marine sponge Leucetta microrhaphis (1992) (35)
- Total syntheses of (+)- and (-)-didemnenones A and B. Anti selectivity in the intramolecular carbomercuration reaction (1990) (35)
- Chlorophyllonic acid and methyl ester, a new chlorophyll a related compound isolated as an antioxidant from short-necked clam, ruditapes philippinarum (1992) (35)
- Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase. (2006) (35)
- Substituent effects on the stereochemistry of substituted cyclohexanone dimethylhydrazone alkylations. An x-ray crystal structure of lithiated cyclohexanone dimethylhydrazone (1984) (35)
- The Selectivity of Austocystin D Arises from Cell-Line-Specific Drug Activation by Cytochrome P450 Enzymes (2011) (35)
- Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A (2020) (35)
- C15 halogenated compounds from the Hawaiian marine alga Laurencia nidifica. Maneonenes and isomaneonenes (1978) (35)
- Tricyclic diterpenoids of the dolastane ring system from the marine alga dictyota divaricata (1981) (34)
- Stylocheilamide, an unusual constituent of the sea hare Stylocheilus longicauda (1978) (34)
- Dapdiamides, Tripeptide Antibiotics Formed by Unconventional Amide Ligases† (2009) (34)
- A Sexually Conditioned Switch of Chemosensory Behavior in C. elegans (2013) (34)
- Colorimetric High-Throughput Screen for Detection of Heme Crystallization Inhibitors (2009) (34)
- Sporulenes, Heptaprenyl Metabolites from Bacillus subtilis Spores (2008) (34)
- FeeM, an N-acyl amino acid synthase from an uncultured soil microbe: structure, mechanism, and acyl carrier protein binding. (2006) (33)
- Limonoid antifeedants from seed of Sandoricum koetjape. (1991) (33)
- Triticones A and B, novel phytotoxins from the plant pathogenic fungus Drechslera tritici-repentis (1988) (33)
- Tridachione, a propionate-derived metabolite of the opisthobranch mollusc Tridachiella diomedea (1978) (33)
- Petrosamine, a novel pigment from the marine sponge Petrosia sp. (1988) (33)
- Cyclynes. Part 5. Pericyclynes: "exploded cycloalkanes" with unusual orbital interactions and conformational properties. MM2 and STO-3G calculations, x-ray crystal structures, photoelectron spectra, and electron transmission spectra (1985) (33)
- Bactobolin Resistance Is Conferred by Mutations in the L2 Ribosomal Protein (2012) (33)
- Inhibition of tumor cells interacting with stromal cells by xanthones isolated from a Costa Rican Penicillium sp. (2012) (33)
- Chromodorolide A, a rearranged diterpene with a new carbon skeleton from the Indian Ocean nudibranch Chromodoris cavae (1989) (33)
- The biosynthetic gene cluster of Pantocin a provides insights into biosynthesis and a tool for screening. (2003) (33)
- Celorbicol, isocelorbicol, and their esters: new sesquiterpenoids from Celastrus orbiculatus (1976) (33)
- Boll weevil antifeedants from Arundo donax. (1993) (32)
- Topoisomerase II-mediated DNA cleavage by adocia- and xestoquinones from the Philippine sponge Xestospongia sp. (1995) (32)
- Total chemical synthesis of lassomycin and lassomycin-amide. (2016) (32)
- New naphthoquinones and a new δ-lactone produced by endophytic fungi from Costa Rica. (2011) (32)
- Chemical investigation of the metabolites from the Canadian tuckahoe, Polyporus tuberaster. (1992) (32)
- Complete Asymmetric Induction in Synthesis of Enantiomerically Pure Steroid Intermediates of Natural Configuration (1981) (32)
- HIV Inhibitory Natural Products. Part 3. Diterpenes from Homalanthus acuminatus and Chrysobalanus icaco. (1991) (32)
- Structure of the Human 25 kDa FK506 Binding Protein Complexed with Rapamycin (1996) (32)
- Synthesis of the Rosette-Inducing Factor RIF-1 and Analogs (2014) (32)
- Triticones, Spirocyclic Lactams from the Fungal Plant Pathogen Drechslera tritici-repentis (1993) (32)
- Structures of rugulovasine-A and -B and 8-chlororugulovasine-A and -B (1976) (32)
- Neolemnane and eremophilane sesquiterpenoids from the pacific soft coral lemnalia africana (1981) (32)
- Synthesis and characterization of new metal-metal bonded species. 2. Crystal and molecular structure of dimeric niobium(III) and tantalum(III) bromide adducts with tetrahydrothiophene. Direct stereochemical evidence of bonding electron density in confacial bioctahedra with metal-metal double bonds (1978) (32)
- Sulfoxide-mediated intramolecular hydroxylation of a remote olefin in an acyclic system (1984) (32)
- Clavicipitic acid: its structure, biosynthesis, and role in ergot alkaloid formation (1980) (31)
- Development of a fluorescence polarization based assay for histone deacetylase ligand discovery. (2008) (31)
- Characterization and molecular structure of 1-hydro-2,8,9-trioxa-1-phospha-5-aza-tricyclo[3.3.3.0]undecane tetrafluoroborate. Pentacoordination of phosphorus (2002) (31)
- Oxindole alkaloids from Gelsemium elegans (1990) (31)
- A non-radioactive DAPI-based high-throughput in vitro assay to assess Plasmodium falciparum responsiveness to antimalarials--increased sensitivity of P. falciparum to chloroquine in Senegal. (2010) (31)
- (3R,4S,7S)-trans, trans-3,7-Dimethyl-1,8,8-tribromo-3,4,7-trichloro-1,5-octadiene, a novel monoterpene from the sea hare, Aplysia californica (1973) (31)
- Smenochromenes, unusual macrocyclic sesquiterpene hydroquinone derivatives from a Seychelles sponge of the genus Smenospongia (1991) (31)
- Aminoindoles, a Novel Scaffold with Potent Activity against Plasmodium falciparum (2011) (31)
- Total synthesis of cyclobutane amino acids from atelia herbert smithii (1988) (31)
- Conformational properties of 2,4-methanoproline (2-carboxy-2,4-methanopyrrolidine) in peptides: determination of preferred peptide bond conformation in aqueous solution by proton Overhauser measurements (1986) (31)
- Renierone, an antimicrobial metabolite from a marine sponge (1979) (31)
- Production of kanosamine by Bacillus cereus UW85. Appl Environ Microbiol (1996) (31)
- Natural Products and Synthetic Biology (2014) (31)
- Tetracyclo[8.2.2.22,5.26,9[octadeca-1,5,9-triene (1984) (30)
- The sterpuric acids: A new type of sesquiterpenoid† (1981) (30)
- Characterization of Plasmodium Liver Stage Inhibition by Halofuginone (2012) (30)
- Sesbanine, a novel cytotoxic alkaloid from Sesbania drummondii (1979) (30)
- Synthesis and crystallographic analysis of a bicyclic core related to the esperamicin/calichemicin aglycones (1989) (30)
- Discovery of 3-Formyl-Tyrosine Metabolites from Pseudoalteromonas tunicata through Heterologous Expression (2009) (30)
- Chiral 1,4-dihydropyridines. Synthesis and absolute configuration. (1981) (30)
- Biosynthetic studies on polypropionates : a stereochemical model for siphonarins A and B from the pulmonate limpet Siphonaria zelandica (1994) (30)
- Crystallization and X-ray Analysis of Stemphyloxin I, a Phytotoxin from Stemphylium botryosum (1983) (30)
- The three-dimensional structure of neohalicholactone, an unusual fatty acid metabolite from the marine sponge halichondria okadai kadota (1991) (30)
- Synthesis of disodium prephenate and disodium epiprephenate. Stereochemistry of prephenic acid and an observation on the base-catalyzed rearrangement of prephenic acid to p-hydroxyphenyllactic acid (1979) (29)
- A plant-responsive bacterial-signaling system senses an ethanolamine derivative (2018) (29)
- Tryptorubin A: A Polycyclic Peptide from a Fungus-Derived Streptomycete (2017) (29)
- The structure and biogenetic origin of (-) halicyclamine B from a Xestospongia sponge (1996) (29)
- Experimental evidence for orbital symmetry control of stereochemistry in some (methylenecyclopropane)iron-carbonyl reactions (1981) (29)
- Metabolites of the dorid nudibranch Chromodoris sedna (1983) (29)
- Pyrrolosporin A, a new antitumor antibiotic from Micromonospora sp. C39217-R109-7. II. Isolation, physico-chemical properties, spectroscopic study and X-ray analysis. (1996) (29)
- Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space (2018) (29)
- The structure of pacifigorgiol, an ichthyotoxic sesquiterpenoid from the pacific gorgonian coral (1982) (28)
- Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export. (2005) (28)
- Terpenoids from the sponge Aplysilla glacialis and specimens of the nudibranch Cadlina luteomarginta found on the sponge (1991) (28)
- Structure of brianthein W, from the soft coral Briareum polyanthes (1984) (28)
- Identity of the stereochemistry of dinosterol and gorgosterol side chain (1978) (28)
- Synthesis of 5,6-dideoxy-3-O-methyl-5-C-(phenylphosphinyl)-d-glucopyranose and its 1,2,4-triacetate (1979) (28)
- Site-directed mutagenesis of monofunctional chorismate mutase engineered from the E. coli P-protein. (1996) (28)
- The chemistry of .gamma.-oxosulfones. 1. A novel rearrangement and a method for the .beta.-alkylation of .alpha.,.beta.-unsaturated ketones (1977) (28)
- Synthesis of 2,4-methanoproline (1981) (28)
- Isolation and Synthesis of a Bacterially Produced Inhibitor of Rosette Development in Choanoflagellates (2016) (28)
- Kempene-1 and -2, unusual tetracyclic diterpenes from Nasutitermes termite soldiers (1977) (28)
- Isolation and structures of two new polycyclic ethers from gymnodinium breve davis (=ptychodiscus brevis) (1985) (28)
- Capsular polysaccharide correlates with immune response to the human gut microbe Ruminococcus gnavus (2021) (28)
- Gelsamydine, an indole alkaloid from Gelsemium elegans with two monoterpene units (1989) (27)
- Neoconcinndiol hydroperoxide, a novel marine diterpenoid from the red alga Laurencia. (1977) (27)
- SOME METABOLITES OF THE MARINE SPONGES SMENOSPONGIA AUREA AND SMENOSPONGIA (POLYFIBROSPONGIA) ECHINA (1980) (27)
- Induction of apoptosis in endometrial cancer cells by psammaplysene A involves FOXO1. (2009) (27)
- Structure of the tremor-producing indole, TR-2. (1975) (27)
- Variation among known kalihinol and new kalihinene diterpenes from the sponge Acanthella cavernosa (1994) (27)
- Emeniveol; A new pollen growth inhibitor from the fungus, Emericella nivea (1992) (27)
- The structure of a new type of plant growth inhibitor extracted from immature tobacco leaves (1975) (27)
- A new monoterpene glycoside of Paeonia lactiflora. (1984) (27)
- Metabolites produced by the scleroderris canker fungus, Gremmeniellaabietina. Part 2. The structure of scleroderolide (1987) (27)
- Animals in a bacterial world: opportunities for chemical ecology. (2015) (26)
- Three new diterpene isonitriles from a Palauan sponge of the genus Halichondria (1987) (26)
- Chemical Interrogation of the Malaria Kinome (2014) (26)
- Polarized crystal absorption spectra and crystal structure for potassium tetrabromoplatinate(II) (1974) (26)
- Atomic structure of the Immunophilin FKBP13-FK506 Complex: Insights into the Composite Binding Surface for Calcineurin (1994) (26)
- Elsamicins A and B, new antitumor antibiotics related to chartreusin. II: Structures of elsamicins A and B (1987) (26)
- Synthesis of long-chain fatty acid enol esters isolated from an environmental DNA clone. (2003) (26)
- Generation and trapping of 6,6-dimethyl-6-silafulvene (1981) (26)
- Studies on a biomimetic approach to aerothionin and psammaplysin-A (1987) (26)
- Pantocin B, an Antibiotic from Erwinia herbicola Discovered by Heterologous Expression of Cloned Genes (1999) (26)
- Bionectriol A, a polyketide glycoside from the fungus Bionectria sp. associated with the fungus-growing ant, Apterostigma dentigerum. (2009) (26)
- Comparison of the structures of the cyclotheonamide a complexes of human α‐thrombin and bovine β‐trypsin (1996) (25)
- Diketone cembrenolides from the pacific gorgonian lophogorgia alba (1982) (25)
- Electronic control of stereoselectivity. 5. Stereochemistry of singlet oxygen capture by cyclopentadiene rings fused to norbornyl and norbornenyl frameworks (1980) (25)
- Luteone, a twenty three carbon terpenoid from the dorid nudi branch Cadlina luteomarginata (1981) (25)
- Trikentramine, an unusual pyrrole derivative from the sponge trikentrion loeve carter (1990) (25)
- STRUCTURE OF VERRUCULOGEN, A TREMOR PRODUCING PEROXIDE FROM PENICILLIUM VERRUCULOSUM (1974) (25)
- Total synthesis of (-)-ovatolide (1993) (25)
- Two new roridins isolated from Myrothecium sp. (2001) (25)
- Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts. (2015) (25)
- Ceriopsin E, a new epoxy ent-kaurene diterpenoid from Ceriops decandra. (2002) (25)
- Linear Peptides Are the Major Products of a Biosynthetic Pathway That Encodes for Cyclic Depsipeptides. (2017) (25)
- The isolation and structure determination of chilenone A, a putative dimer of 2-methyl-3(2H)-furanone from the marine alga (1983) (25)
- 1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2. (2013) (25)
- Peridinosterol - a new Δ17-unsaturated sterol from two cultured marine algae (1980) (25)
- 5-Isothiocyanatopupukeanane from a sponge of the genus Axinyssa (1989) (25)
- Synthesis of the angular anthraquinone subunit of dynemicin A (1991) (25)
- 19-(R)- and 19-(S)-Hydroxydihydrokoumine from Gelsemium elegans (1990) (25)
- Terpenoic acid glycerides from the dorid nudibranch (1984) (25)
- Letter: Nasute termite soldier frontal gland secretions. 1. Structure of trinervi-2 beta, 3 alpha, 9 alpha-triol 9-o-acetate, a novel diterpene fromTrinervitermes soldiers. (1976) (25)
- Structure of the spiroketal-macrolide ossamycin. (1996) (25)
- Structure of crotofolin A, a diterpene with a new skeleton (1975) (24)
- SYNTHESIS AND PROPERTIES OF CHALCOGEN‐BRIDGED NAPHTHALENES: A NEW SERIES OF ELECTRON DONORS * (1978) (24)
- Synthesis, Structure and Mechanism in Immunophilin Research (1994) (24)
- Diterpenes from Dictyota dichotoma (1977) (24)
- Actin-aggregating cucurbitacins from Physocarpus capitatus. (2008) (24)
- Anthosterones A and B, ring A contracted steroids from the sponge Anthoracuata graceae (1988) (24)
- Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors (2016) (24)
- Preparation, properties, and crystal structure of a cationic nickel nitrosyl bicyclic phosphite complex (1975) (24)
- Iridoid glycosides from Barleria lupulina. (2015) (24)
- STRUCTURAL BASIS FOR PEPTIDOMIMICRY BY A NATURAL PRODUCT (1994) (24)
- Structures and possible functions of epoxypukalide and pukalide (1989) (24)
- THREE OXINDOLE ALKALOIDS FROM GELSEMIUM SPECIES (1991) (24)
- Curvulin and O-methylcurvulinic acid: phytotoxic metabolites of Drechslera indica which cause necroses on purslane and spiny amaranth. (1989) (24)
- Lemnalol, a new sesquiterpenoid from the soft coral Verseveldt (1982) (24)
- Synthesis and electronic properties of 2a,8b-dihydrocyclopent[cd]azulenes (elassovalenes) (1977) (24)
- A limonoid antifeedant from seed of Carapa procera. (1988) (23)
- Zwittermicin A, an Antifungal and Plant Protection Agent from Bacillus cereus. (1994) (23)
- A pterocarpan and two isoflavans from alfalfa (1991) (23)
- Fijiensin, the first phytotoxin fromMycosphaerella fijiensis, the causative agent of Black Sigatoka disease (1990) (23)
- APLASMOMYCIN C : STRUCTURAL STUDIES OF A MARINE ANTIBIOTIC (1991) (23)
- Two new xenicin diterpenoids from the octocoral anthelia edmondsoni (1984) (23)
- Mycotoxins produced by Aspergillus fumigatus isolated from silage. (1977) (23)
- Antitumor plants. 11. Diterpenoid and flavonoid constituents of Bromelia pinguin L (1981) (23)
- Tridentatols A-C, novel natural products of the marine hydroid Tridentata marginata (1996) (23)
- Laurencione, a heterocycle from the red alga Laurencia spectabilis (1992) (23)
- Gelsemamide and 11-methoxygelsemamide, two novel secoindole alkaloids from gelsemium elegans (1989) (23)
- Antiplasmodial activity of piperazine sulfonamides. (2010) (23)
- Synthesis and chemistry of tetracyclo[8.2.2.22,5.26,9]-1,5,9-octadecatriene (1986) (23)
- A stereoselective synthesis of two stereoisomers of demethylgorgosterol. (1975) (23)
- Gene Flow and Molecular Innovation in Bacteria (2016) (22)
- AFZELIN AND UVAFZELIN, NOVEL CONSTITUENTS OF UVARIA AFZELII (1981) (22)
- A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity. (2010) (22)
- TRYPTOQUIVALINE AND TRYPTOQUIVALONE, TWO TREMORGENIC METABOLITES OF ASPERGILLUS CLAVATUS (1975) (22)
- Microbial community modulates growth of symbiotic fungus required for stingless bee metamorphosis (2019) (22)
- Ohioensins : novel benzonaphthoxanthenones from Polytrichum ohioense (1993) (22)
- Acanthodoral and isoacanthodoral, two sesquiterpenoids with new carbon skeletons from the dorid nudibranch Acanthodoris nanaimoensis (1984) (22)
- A novel rearrangement of a papaverine derivative into isoquino [1,2-b]-quinazoline derivative (1987) (22)
- Cycloheximide-Producing Streptomyces Associated With Xyleborinus saxesenii and Xyleborus affinis Fungus-Farming Ambrosia Beetles (2019) (22)
- Pyrenoline-A and -B, two new phytotoxins from Pyrenophora teres (1990) (22)
- Phenolic compounds as antiangiogenic CMG2 inhibitors from Costa Rican endophytic fungi. (2012) (22)
- Exserohilone: a novel phytotoxin produced by Exserohilum holmii (1985) (22)
- Cleocarpone, a triterpenoid from Cleome brachycarpa. (1990) (22)
- Phidolopine, a new purine derivative from the bryozoan Phidolopora pacifica (1984) (22)
- Calyculones, new cubitane diterpenoids from the Caribbean gorgonian octocoral Eunicea calyculata (1984) (22)
- A pregnane steroid from Aglaia lawii and structure confirmation of cabraleadiol monoacetate by X-ray crystallography. (2001) (22)
- Anticancer Agents from Unique Natural Products Sources (2003) (22)
- Isolation and structure determination of the mycotoxin chaetoglobosin C, a new [13] cytochalasin (1976) (22)
- Salvadiones-A and -B: Two Terpenoids Having Novel Carbon Skeleta from Salvia bucharica (1999) (22)
- Chemical constituents of tropical plants. V. Structures of suaveolic acid and suaveolol (1974) (22)
- Synthesis and structure of dicarbonyldi-η-cyclopentadienylbis(μ-thiocarbonyl)diiron, a thiocarbonyl analog of the dicarbonyl-η-cycglopentadienyliron dimer (1976) (22)
- Gilmicolin and Mycorrhizinol, Two New Metabolites of Gilmaniella humicolaBARRON (1979) (21)
- Violacene: A reassignment of structure (1978) (21)
- Identification of Protein Kinase C Activation as a Novel Mechanism for RGS2 Protein Upregulation through Phenotypic Screening of Natural Product Extracts (2014) (21)
- Isolation and structure determination of two novel Lathyrenes from Jatropha Curcus (1986) (21)
- New diterpenes from the common Caribbean gorgonian Briareum asbestinum (Pallus) (1981) (21)
- Palmosalides A-C, new sesquiterpenoids from the indian ocean telestacean octocoral Coelogorgia palmosa (1990) (21)
- Marginatafuran. a furanoditerpene with a new carbon skeleton from the dorid nudibranch (1985) (21)
- Natural products: Beyond grind and find. (2009) (21)
- Crystal and molecular structure of tetrakis(trimethyl phosphite-di-.mu.-nitrato-disilver(I). Case of symmetric nitrate-oxygen bridging (1975) (21)
- Pyonitrins A–D: Chimeric Natural Products Produced by Pseudomonas protegens (2019) (21)
- Phytoecdysteroids of Diploclisia glaucescens seed. (1985) (21)
- Cadabicine, an alkaloid from Cadaba farinosa (1985) (21)
- Luffolide, a novel anti-inflammatory terpene from the spongeLuffariella sp. (1989) (21)
- Secondary metabolites from the red alga Laurencia intricata: halogenated enynesl (1982) (21)
- Vafzelin and uvafzelin, novel constituents of Uvaria afzelii (1980) (21)
- Absolute configuration of brevetoxins (1986) (21)
- Tundrenone: An Atypical Secondary Metabolite from Bacteria with Highly Restricted Primary Metabolism (2018) (21)
- .alpha.-Halo sulfones. XVII. Directive effects in the chlorination of thiapropellanes (1971) (20)
- 2-amino-4-acetylaminobutyric acid, 2,4-diaminobutyric acid and 2-amino-6N-oxalylureidopropionic acid (oxalylalbizziine) in seeds of acacia angustissima (1985) (20)
- Honulactones: new bishomoscalarane sesterterpenes from the Indonesian sponge Strepsichordaia aliena. (2000) (20)
- Synthesis of spiro-1,2-dioxolanes and their activity against Plasmodium falciparum. (2008) (20)
- Structure of the new spiroketal-macrolide A82548A. (1995) (20)
- Sphaerococcenol A; a new rearranged bromo-diterpene from the red alga (1976) (20)
- Mononitroxides and proximate dinitroxides derived by oxidation of 2,2,4,4,5,5-hexasubstituted imidazolidines. A new series of nitroxide and dinitroxide spin labels (1978) (20)
- A cholesteryl ester transfer protein inhibitor from an insect-associated fungus. (1996) (20)
- Phytotoxins from plant pathogens of weedy plants (1987) (20)
- Discovery of Dual-Stage Malaria Inhibitors with New Targets (2015) (20)
- Erythrodiene: A new spirobicyclic sesquiterpene of a rare skeletal class from the caribbean gorgonian coral Erythropodium caribaeorum (1993) (20)
- A new antibacterial octaketide and cytotoxic phenylethanoid glycosides from Pogostemon cablin (Blanco) Benth. (2015) (20)
- Sesquiterpenes from Pityrogramma calomelanos (1978) (20)
- Aflavinine, a novel indole-mevalonate metabolite from tremorgen-producing species (1980) (20)
- A new diterpene fromAplysia dactylomela (1983) (20)
- Crispatone, a metabolite of the opisthobranch mollusc Tridachia crispata [1] (1979) (19)
- Silicon-carbon double-bond formation via 1,5-sigmatropic migration of trimethylsilyl from silicon to carbon (1979) (19)
- Borrowing to make ends meet. (1999) (19)
- Schisanlactone A, a new type of triterpenoid from a . (1983) (19)
- Dynamics of Snake-like Swarming Behavior of Vibrio alginolyticus. (2016) (19)
- Unsaturated heterocyclic systems. XCI. Stereochemical and substituent effects in chlorosulfonyl isocyanate additions to cis-bicyclo[6.1.0] nonatrienes (1973) (19)
- ZmaR, a Novel and Widespread Antibiotic Resistance Determinant That Acetylates Zwittermicin A (1999) (19)
- Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes (2018) (19)
- N-Methoxyanhydrovobasinediol from Gelsemium elegans (1989) (19)
- Sesterterpenes. 1. Stereospecific construction of the ceroplastol and ophiobolin ring systems via a common bicyclic intermediate (1977) (19)
- The absolute configuration of bacillariolides I and II, a new type of cyclopentane icosanoids from a marine diatom (1993) (19)
- Cyclic AMP Directly Activates NasP, an N-Acyl Amino Acid Antibiotic Biosynthetic Enzyme Cloned from an Uncultured β-Proteobacterium (2007) (19)
- Organic oxalates. VI. Pyrolysis of di(.alpha.-substituted)benzyl oxalates (1971) (19)
- Heterocyclopentadienes. II. Reaction of benzenediazonium-2-carboxylate with 1,1-dimethyl-2,5-diphenyl-1-silacyclopentadiene (1972) (19)
- Further structural studies on the 2-methyl-3(2H)-furanone derived metabolites of the marine alga Laurencia chilensis (1987) (19)
- A new dihydrobenz[a]anthraquinone antitumor antibiotic (PD 116 740) (1985) (18)
- Stereochemical and Conformational Effects on the Cycloaromatization of Dynemicin A-Related Molecules (1995) (18)
- Korupensamines A‐D, Novel Antimalarial Alkaloids from Ancistrocladus korupensis. (1995) (18)
- Podoandin, a molluscicidal sesquiterpene lactone from Podocarpus andina (1992) (18)
- A quassinoid from Brucea javanica. (1990) (18)
- Nuclear magnetic resonance and molecular structural studies of trans-P(OCH2)3PFe(CO)3P(OCH2)3P (1972) (18)
- Dictyoxepin and dictyolene, two new diterpenes from the marine alga Dictyota acutiloba (Phaeophyta) (1977) (18)
- The synthesis of potentially selective inhibitors of dihydroorotate dehydrogenase. The utilization of chemoselective Suzuki cross-coupling reactions in a parallel synthesis (2001) (18)
- Podoandin, a molluscicidal sesquiterpene lactone from Podocarpus andina (1992) (18)
- The rhodophytin and chondriol natural products; structures of several new acetylenes from laurencia, and a reassignment of structure for cis-rhodophytin (1980) (18)
- Alteichin: an unusual phytotoxin fromAlternaria eichorniae, a fungal pathogen of water hyacinth (1984) (18)
- Havellockate, A Novel Seco and Spiro Lactone Diterpenoid from the Indian Ocean Soft Coral Sinularia granosa (1998) (18)
- CHLOROACETYLENES AS MICHAEL ACCEPTORS. 3. MECHANISM AND SYNTHETIC UTILITY OF ENOLATE REACTIONS WITH HALOGENATED OLEFINS AND CHLOROACETYLENES (1984) (18)
- Cycloaddition of azides to hexamethyl (Dewar benzene) (1972) (18)
- Agrochemical activity and isolation of N-(4'-bromophenyl)-2,2-diphenylacetanilide from the Thai plant Arundo donax. (1993) (18)
- Synthesis applications of aza-cope rearrangements : A stereoselective synthesis of 9a-arylhydrolilolidines [and a new approach to the synthesis of aspidosperma] alkaloids (1981) (18)
- Biflora-4,10(19),15-triene: a new diterpene from a termite soldier (Isoptera Termitidae Termitinae) (1980) (18)
- Using scalarane sesterterpenes to examine a sponge taxonomic anomaly. (1997) (17)
- Plasmalogen Biosynthesis by Anaerobic Bacteria: Identification of a Two-Gene Operon Responsible for Plasmalogen Production in Clostridium perfringens (2020) (17)
- Aryl trifluoromethyl ketone hydrates as precursors of carboxylic acids and esters1 (1992) (17)
- A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity (2020) (17)
- Relative and absolute stereochemistry of the didemnaketals, metabolites of a Palauan ascidian, Didemnum sp. (2002) (17)
- Crotofolane diterpenoids from the African shrub Croton dichogamus Pax. (1989) (17)
- Norsesterterpene peroxides from the sponge Latrunculia sp (1991) (17)
- Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis. (2011) (17)
- Using genomics to deliver natural products from symbiotic bacteria (2005) (17)
- Letter: A revised structure for the antibiotic pillaromycin A. (1975) (17)
- Dysoxysulfone, a sulfur rich metabolite from the Fijian medicinal plant dysoxylum richii (1989) (16)
- Ohioensin-A: a novel benzonaphthoxanthenone from Polytrichum ohioense (1989) (16)
- Fluoroprostaglandins: synthesis and biological evaluation of the methyl esters of (+)-12-fluoro-, (-)-ent-12-fluoro-, (+)-15-epi-fluoro-, and (-)-ent-15 epi-12-fluoroprostaglandin F2 alpha. (1980) (16)
- Crystal structure of P13K SH3 domain at 20 angstroms resolution. (1996) (16)
- Irieol A and iriediol, dibromoditerpenes of a new skeletal class from (1975) (16)
- Gilmaniellin and Dechlorogilmaniellin, Two Novel Dimeric Oxaphenalenones (1979) (16)
- Structure and synthesis of a new butanolide from a marine actinomycete (1991) (16)
- Phytotoxins from the Septoria spp. plant pathogenic fungus on leafy spurge. (1998) (16)
- Poitediol, a new nonisoprenoid sesquiterpene diol from the marine alga Laurencia poitei (1978) (16)
- Synthesis and biological evaluation of analogues of the antibiotic pantocin B. (2001) (16)
- 3H-Cyclonona[def]biphenylene. An example of neutral homoantiaromaticity. (1986) (16)
- Pantocin B, an Antibiotic from Erwinia herbicola Discovered by Heterologous Expression of Cloned Genes. (2000) (16)
- Emblide, a new polyfunctional cembranolide from the soft coral sarcophyton glaucum (1980) (16)
- Crystal and molecular structure of pentakis(4-methyl-1-phospha-2,6,7-trioxabicyclo(2. 2. 2)octane)cobalt(I)(acetonitrile)trinitratocobalt(II), Co(P(OCH/sub 2/)/sub 3/CMe)/sub 5/ (Co(NO/sub 3/)/sub 3/NCMe) (1977) (16)
- Pharbinilic acid, an allogibberic acid from morning glory (Pharbitis nil). (2013) (16)
- Desmethoxyviridiol, a new toxin from Nodulisporium hinnuleum (1975) (16)
- Chemical inducers of dimerization: the atomic structure of FKBP12-FK1012A-FKBP12. (1998) (16)
- Two new metabolites of the sponge Dysidea amblia and revision of the structure of ambliol B (1984) (16)
- Sarcophytin, A Novel Tetracyclic Diterpenoid From The Indian Ocean Soft Coral Sarcophyton elegans (1998) (16)
- Conformational properties of 2,4-methanoproline (2-carboxy-2,4-methanopyrrolidine) in peptides: evidence for 2,4-methanopyrrolidine asymmetry based on solid-state x-ray crystallography, proton NMR in aqueous solution, and CNDO/2 conformational energy calculations (1987) (16)
- Isolation and structure of bohemamine (1a.beta.,2.alpha.,6a.beta.,6b.beta.)-3-methyl-N-(1a,6,6a,6b-tetrahydro-2,6a-dimethyl-6-oxo-2H-oxireno[a]pyrrolizin-4-yl)-2-butenamide (1980) (16)
- Δ 9(15)-Africanene, a new sesquiterpene hydrocarbon from the soft coralSinularia erecta (1980) (15)
- Obtusin, a unique bromine-containing polycyclic ketal from the red marine alga (1979) (15)
- Synthesis of 10-selenatricyclo[3.3.3.03,7]undec-3(7)-ene. X-ray structure of an alkene containing a pyramidalized double bond (1987) (15)
- Kedarcidin chromophore: Structure elucidation of the amino sugar kedarosamine (1992) (15)
- A novel stereocontrolled preparation of phospho sugar derivatives from phospholenes (1988) (15)
- esized and post-translationally modi fi ed peptide natural products : overview and recommendations for a universal nomenclature (2012) (15)
- The isolation of new norcycloartene triterpenoids from the tropical marine alga (chlorophyta) (1982) (15)
- Mortality risk and clozapine. (1995) (15)
- Structure of the diterpene portion of a novel base from the sponge Agelas mauritiana (1984) (15)
- A vinyl carbonimidic dichloride from the marine sponge (1978) (15)
- Synthesis, trapping, and dimerization of 9,10-benzotricyclo[3.3.2.03,7]deca-3(7),9(10)-diene. X-ray crystal structure of the dimer (1977) (15)
- A Machine Learning Bioinformatics Method to Predict Biological Activity from Biosynthetic Gene Clusters (2021) (15)
- Volutamides A-E, halogenated alkaloids with antifeedant properties from the Atlantic bryozoan Amathia convoluta (1996) (15)
- Traditional Medicine Collection Tracking System (TM-CTS): a database for ethnobotanically driven drug-discovery programs. (2011) (15)
- Metabolites of Siphonaria maura from Costa Rica (1986) (15)
- Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) (2013) (15)
- Mamanine and pohakuline, two unprecedented quinolizidine alkaloids from sophora chrysophylla☆ (1976) (15)
- Pinthunamide, a new tricyclic sesquiterpene amide produced by a fungus, Ampullifernia sp (1989) (15)
- The crystal structure of (+)-d-tris(ethylenediamine)cobalt(III) nitrate (1972) (14)
- Solid-state coordination bonding to polyvalent iodine—The structure of 1-acetoxy-1,2-benziodoxolin-3-one (1972) (14)
- X‐RAY DETERMINATION OF CHONDRIOL, A RE‐ASSIGNMENT OF STRUCTURE (1974) (14)
- Electronic control of stereoselectivity. 15. Stereoselectivity of Diels-Alder cycloadditions to norbornyl- and norbornenyl-fused spirocyclic cyclopentadiene systems (1983) (14)
- Specialized Metabolites Reveal Evolutionary History and Geographic Dispersion of a Multilateral Symbiosis (2021) (14)
- Rhodolaureol and rhodolauradiol, two new halogenated tricyclic sesquiterpenes from a marine alga (1985) (14)
- Chloriolins A‐C, Chlorinated Sesquiterpenes Produced by Fungal Cultures Separated from a Jaspis Marine Sponge. (1995) (14)
- ABSOLUTE STEREOCHEMISTRY AND DOPAMINERGIC ACTIVITY OF ENANTIOMERS OF 2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINE (1982) (14)
- Total synthesis of (+)-didemnenones A and B: absolute configurations of the didemnenones (1988) (14)
- Variable reaction pathways for the action of polysulfide on Michael acceptors (1985) (14)
- Molecular conformation of destruxin A (1989) (14)
- Synthesis and dimerization of tricyclo[3.3.3.02,6]undec-2(6)-ene. X-ray structure of the dimer as evidence for a concerted ene reaction in dimer formation (1977) (14)
- Trididemnic acids A and B, aromatic alkaloids from the northeastern pacific ascidian (1992) (14)
- Structural revision of aspirochlorine (=antibiotic A30641), a novel epidithiopiperazine-2, 5-dione produced byaspergillus SPP. (1987) (14)
- A New Tremorgenic Metabolite Related to Verruculogen from Penicillium verruculosum (1982) (14)
- Photochemical transformations. LI. Photoisomerization of 5,5-dimethylbicyclo[4.1.0]hept-3-en-2-one and 4,6,6-trimethylbicyclo[3.1.0]hex-3-en-2-one (1973) (14)
- Garveatin A, an antimicrobial 1(4H)-anthracenone derivative from the hydroid Garveia annulata (1985) (14)
- Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines. (2010) (14)
- Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways* (2015) (13)
- Chlorosilphanol A and silphanepoxol, labdane diterpenes from Silphium perfoliatum. (1994) (13)
- X-ray crystallography: One size fits most (2013) (13)
- Pinnatazane, a bridged cyclic ether sesquiterpene from Laurencia pinnatifida (1988) (13)
- Natural products and morphogenic activity of γ-Proteobacteria associated with the marine hydroid polyp Hydractinia echinata. (2017) (13)
- Chemical Interaction among Termite-Associated Microbes (2017) (13)
- A New Dihydrobenz[a]anthraquinone Antitumor Antibiotic (PD 116740). (1986) (13)
- Revision of the structure of xylomollin (1978) (13)
- Metabolites Involved in Immune Evasion by Batrachochytrium dendrobatidis Include the Polyamine Spermidine (2019) (13)
- Antibiotics produced by strains of Erwinia herbicola that are highly effective in suppressing fire blight. (1990) (13)
- Spontaneous generation of a bridgehead double bond in a seven-membered rings (1972) (13)
- Chakyunglupulins A and B, two novel 4,8,8-trimethylcyclooct-2-enone derivatives from Barleria lupulina. (2015) (13)
- Ellagitannins from Conocarpus erectus exhibit anti-quorum sensing activity against Pseudomonas aeruginosa (2008) (13)
- Structure and absolute configuration of (+)-coronaridine hydrobromide. Absolute configuration of the Iboga alkaloids (1973) (13)
- Preparation of a psammaplysene-based library. (2006) (13)
- The structure of corylifuran, A clerodane-type diterpene from Croton corylifolius lam (1976) (13)
- Novel sesquiterpenoids from the fairy ring fungus, Marasmiusoreades (1989) (13)
- Absolute configuration of vincoside. [X-rayb diffraction studies] (1975) (13)
- Mećhanistic dichotomy in cycloadditions to cyclooctatetraeneiron tricarbonyl. X-ray crystal structure analysis of the TCNE and CSI adducts (1973) (13)
- Silver(I) ion catalyzed rearrangements of strained .sigma. bonds. 33. Benzoannulation as a probe of structural dimension and .pi.-electron distribution in elassovalenes. A mathematical model for the assessment of homoaromaticity (1977) (13)
- Shikimate-derived metabolites revised structure and total synthesis of pipoxide (1979) (13)
- Decomposition of benzenediazonium-3-carboxylate: transient 1,3-dehydrobenzene (1965) (13)
- Uvarinol: a novel cytotoxic tribenzylated flavanone from Uvaria chamae (1979) (13)
- Novel Synthesis and Structure of Phosphanyl Sugar Derivatives 1 (1997) (13)
- Dasytrichone, A Novel Flavone From Dasymaschalon Trichophorum With Cancer Chemopreventive Potential (1992) (13)
- Characterization and molecular structure of 2,2',2''-nitrilotris(ethoxy)thiophosphate. Trigonal planarity of nitrogen (1977) (13)
- New Terpenoid Metabolites from the Skin Extracts, an Egg Mass, and Dietary Sponges of the Northeastern Pacific Dorid Nudibranch Cadlina luteomarginata. (1997) (13)
- ISOLATION AND X-RAY STRUCTURAL DETERMINATION OF THREE NEW DITERPENOIDS FROM THE MARINE ALGA TAONIA ATOMARIA (1984) (12)
- Bissetone, a unique antimicrobial pyranone from the gorgonian (1987) (12)
- Naphthalenones and Isocoumarins from a Costa Rican Fungus Xylariaceae sp. CR1546C (2014) (12)
- Malabarolide, a novel furanoid bisnorditerpenoid from Tinospora malabarica (1988) (12)
- [3.3]Metacyclophane: A Novel Synthesis and a Study of the Structure Through X-Ray Diffraction, Molecular Mechanics, and Solution NMR Analysis. (1986) (12)
- A novel intramolecular redox reaction: the transformation of L-proline to N-amino-2-pyrrolidones via a mesoionic system (1985) (12)
- Novel triterpenoids from the roots of Buxus papillosa (1992) (12)
- A REVISED STRUCTURE OF VERMICULINE, A NOVEL MACROLIDE DILACTONE ANTIBIOTIC FROM PENICILLIUM VERMICULATUM (1974) (12)
- Structural Basis for Peptidomimicry by the Effector Element of Rapamycin (1997) (12)
- PD 125375, a novel metabolite coproduced with tomaymycin (1987) (12)
- Crystal and molecular structures of a natural equimolecular mixture of two epimeric diterpenes (2001) (12)
- Insect antifeedants from tropical plants I. Structure of dumsin. (1990) (12)
- Bond fixation in annulenes. 11. Synthesis and absolute configuration of the enantiomeric 1,3-di-tert-butylcyclooctatetraenes. Quantitative kinetic assessment of the effect of nonvicinal tert-butyl groups on [8]annulene ring-inversion and bond-shifting barriers (1981) (12)
- Crystal and molecular structure of 1,2,5-triphenylphosphole (1971) (12)
- Gersolide, a diterpenoid with a new rearranged carbon skeleton from the soft coral Gersemia rubiformis (1987) (12)
- STRUCTURE OF CYTOCHALASIN E, A TOXIC METABOLITE OF ASPERGILLUS CLAVATUS (1973) (12)
- Detecting binding interactions using microarrays of natural product extracts. (2007) (12)
- Structural studies of natural products by new nmr techniques. The structure of a new polyether antibiotic, portmicin (1987) (12)
- Unusual phosphorus basicity of P(OCH/sub 2/CH/sub 2/)/sub 3/N and the molecular structure of H/sub 3/BP(OCH/sub 2/CH/sub 2/)/sub 3/N (1977) (12)
- The Crystalline Sponge Method: A Solvent-Based Strategy to Facilitate Noncovalent Ordered Trapping of Solid and Liquid Organic Compounds. (2017) (12)
- Biogeography and Microscale Diversity Shape the Biosynthetic Potential of Fungus-growing Ant-associated Pseudonocardia (2019) (11)
- Pollen Streptomyces Produce Antibiotic That Inhibits the Honey Bee Pathogen Paenibacillus larvae (2021) (11)
- The structure and absolute configuration of chondrocolactone, A halogenated monoterpene from the red alga chondrococcus hornemanni, and a revised structure for chondrocole a (1978) (11)
- The Structures of Spirasine V and Spirasine VI. (1986) (11)
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- Bombyx mori pheromone binding protein bound to iodohexadecane (2007) (0)
- HUMAN TISSUE TRANSGLUTAMINASE IN GDP BOUND FORM (2002) (0)
- CDC42HS-GDP COMPLEX (1999) (0)
- Anions of Chalcone-Epoxides. (2010) (0)
- PD 125375, a Novel Metabolite Coproduced with Tomaymycin. (1987) (0)
- PREPARATION OF 6β-IMIDOPENICILLINATE 1(S)-OXIDES (1978) (0)
- Toxines fongicides obtenues a partir de bacteries, utilisables pour la protection biologique (1995) (0)
- Additions and Corrections - A Revised Structure of Vermiculine. A novel Macrolide Dilactone Antibiotic from Penicillium vermiculatum. (1975) (0)
- Correction for ‘‘Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo,’’ by W. A. Kues, S. Sud- (2009) (0)
- Solid-State and Solution Studies of Lithiated 2-Carbomethoxycyclohexanone Dimethylhydrazone and Lithiated Cyclohexanone Phenylimine. (1986) (0)
- X-Ray crystal and molecular structure of the triterpenoid 24,25-dibromokulactone (1971) (0)
- Sarcophytin, a Novel Tetracyclic Diterpenoid from the Indian Ocean Soft Coral Sarcophyton elegans. (2010) (0)
- Structural analysis of rapamycin's role in binding FKBP12 and FRAP (1996) (0)
- Additions and Corrections - " Terpenoids. LXX. The Structure of the Sea Cucumber Sapogenin Holotoxinogenin." (1975) (0)
- ISOLATION AND STRUCTURE OF BREVETOXIN B FROM THE “RED TIDE” DINOFLAGELLATE PTYCHODISCUS BREVIS (GYMNODINIUM BREVE) (1982) (0)
- Isolation and Structure of Rebeccamycin. A New Antitumor Antibiotic from No- cardia aerocoligenes. (1986) (0)
- Pity the stinking yew (1996) (0)
- Decision letter: Doxycycline has distinct apicoplast-specific mechanisms of antimalarial activity (2020) (0)
- Cover Picture: Isolation and Structural Proof of the Large Diamond Molecule, Cyclohexamantane (C26H30) (Angew. Chem. Int. Ed. 18/2003) (2003) (0)
- CCDC 216873: Experimental Crystal Structure Determination (2003) (0)
- Inside front cover. (2018) (0)
- Conformational Properties of 2,4-Methanoproline (2-Carboxy-2,4-methanopyrrolidine) in Peptides: Evidence for 2,4-Methanopyrrolidine Asymmetry Based on Solid-State X-Ray Crystallography, 1H NMR in Aqueous Solution, and CNDO/2 Conformat (1987) (0)
- Abstract 5292: Identification of antiangiogenic small molecule natural products targeting anthrax toxin receptor 2 (2012) (0)
- FKBP12-FK1012 COMPLEX (1998) (0)
- Metabolites of the Marine Hydroid Garveia annulata: Garveatins B and C, 2-Hydroxygarvin A and Garvin A Quinone. (1986) (0)
- HUMAN DIHYDROOROTATE DEHYDROGENASE COMPLEXED WITH BREQUINAR ANALOG (2000) (0)
- 3H‐Cyclonona(def)diphenylene: An Example of Neutral Homoantiaromaticity. (1987) (0)
- Annulins A (I) and B (II), Metabolites of the Marine Hydroid Garveia annulata. (1987) (0)
- Total Syntheses of (+)- and (-)-Didemnenones A and B. Antiselectivity in the Intramolecular Carbomercuration Reaction. (1990) (0)
- FLUOROPROSTAGLANDINS: SYNTHESIS AND BIOLOGICAL EVALUATION OF THE METHYL ESTERS OF (+)-12-FLUORO-, (-)-ENT-12-FLUORO-, (+)-15-EPI-FLUORO-, AN (-)-ENT-15-EPI-12-FLUOROPROSTAGLANDIN F2α (1981) (0)
- Phytotoxins from fungal weed pathogens (1989) (0)
- Bacterial Symbionts and Natural Products (2011) (0)
- Total Synthesis of Acetylenic Carotenoids. Part 1. Synthesis of Optically Active 2‐E‐((4R)‐4‐Hydroxy‐2,6,6‐trimethylcyclohex‐1‐enyl)‐3‐ methyl‐2‐penten‐4‐yn‐1‐al, a C15‐Synthon. (1994) (0)
- TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP. (1999) (0)
- AUSTIN, A NOVEL POLYISOPRENOID MYCOTOXIN FROM ASPERGILLUS USTUS (1977) (0)
- ELECTRONIC CONTROL OF STEREOSELECTIVITY. 15. STEREOSELECTIVITY OF DIELS-ALDER R CYCLOADDITIONS TO NORBORNYL- AND NORBORNENYL-FUSED SPIROCYCLIC CYCLOPENTADIENE SYSTEMS (1983) (0)
- Decision letter: A single point mutation in the Plasmodium falciparum FtsH1 metalloprotease confers actinonin resistance (2020) (0)
- FKBP-RAPAMYCIN BINDING DOMAIN (FRB) OF THE FKBP-RAPAMYCIN ASSOCIATED PROTEIN (1998) (0)
- NMR structure of lassomycin (2014) (0)
- ILV/VI-7 DISCOVERING NEW MOLECULES IN NATURE(Molecular Mode of Action on Natural Products and Drugs/Chemical Biology and Related Areas) (2006) (0)
- Decision letter: Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones (2020) (0)
- Lipopeptides produced by Bacillus sp. isolated from larvae of Brazilian stingless bee (2014) (0)
- The Diterpenes of Dictyota dichotoma from the Indian Ocean. (1987) (0)
- Stereochemical and Conformational Effects on the Cycloaromatization of Dynemicin A‐Related Molecules (1995) (0)
- Novel Synthesis and Structure of Phosphanyl Sugar Derivatives. (1997) (0)
- AN UNUSUAL THERMAL REARRANGEMENT OF 5,5,6,6-TETRACYANO-2-THIABICYCLO(2.2.0)HEXANE TO A THIOPHENE (1985) (0)
- Total Synthesis of Cyclobutane Amino Acids (I), (II) from Atelia herbert smithii. (1989) (0)
- Spectral and Conformational Analyses of Humosine A (I). (1995) (0)
- Preparation, Structure, and Properties of 3H-Cyclonona(def)biphenylen- 3-one, a Potentially Antiaromatic Annulenone. (1988) (0)
- η5-CYCLOHEXADIENYLTRICARBONYLCHROMIUM(0) COMPLEXES FROM ADDITION OF CARBON NUCLEOPHILES TO η6-BENZENETRICARBONYLCHROMIUM(0). FORMATION, CHEMICAL AND SPECTROSCOPIC FEATURES, AND X-RAY DIFFRACTION ANALYSIS (1979) (0)
- Resolution of Diastereomeric Sulfoximines. (1991) (0)
- Ohioensin‐A: A Novel Benzonaphthoxanthenone from Polytrichum ohioense (1989) (0)
- MECHANISTIC DICHOTOMY IN CYCLOADDITIONS TO CYCLOOCTATETRAENEIRON TRICARBONYL, X‐RAY CRYSTAL STRUCTURE ANALYSIS OF THE TCNE AND CSI ADDUCTS (1973) (0)
- Emeniveol (I). A New Pollen Growth Inhibitor from the Fungus, Emericella nivea. (1993) (0)
- Total Synthesis of (+)‐Octalactins A and B: Unusual Metabolites from a Marine Microbe. (1995) (0)
- A Novel Stereocontrolled Preparation of Phospho Sugar Derivatives from Phospholenes. (1988) (0)
- Chakyunglupulins A (I) and B (II), Two Novel 4,8,8‐Trimethylcyclooct‐2‐enone Derivatives from Barleria lupulina. (2015) (0)
- The Crystalline Sponge Method: Synthetic and Crystallographic Guidelines (2014) (0)
- Synthesis and Properties of Cycloocta(def)biphenylene-1,4-dione. (1989) (0)
- Bombyx mori pheromone binding protein bound to bell pepper odorant (2007) (0)
- NEW SECONDARY METABOLITES FROM STREPTOMYCES sp . JV 178 , AN ENVIRONMENTAL STRAIN (0)
- Polar Lipid in Human Blood Regulates Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum (2017) (0)
- THE SYNTHESIS OF VAFZELIN AND SYNCARPIN, CONSTITUENTS OF UVARIA AFZELII (1982) (0)
- Molecules, Information, And Life: "The Touchstone of life: Molecular Information, Cell Communication, and the Foundations of life," by Werner R. Loewenstein, Oxford University Press, 1999, 368 pages, $30 (ISBN 0-19-511828-6) (1999) (0)
- CRYSTAL STRUCTURE OF THE PYROGLUTAMYL PEPTIDASE I FROM BACILLUS AMYLOLIQUEFACIENS (1999) (0)
- Stingless Bee Larvae Require Fungal Steroid to Pupate (2018) (0)
- Correction: A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity (2012) (0)
- Abstract 3890: Antiangiogenic small molecule antagonists of the anthrax toxin receptor CMG2. (2013) (0)
- Structural Studies of a New Nuclear Target for EGF Receptor Tyrosine Kinase (2002) (0)
- Co-culture between insect-associated microorganisms stimulates polyketide production (2015) (0)
- Additions and Corrections - Chain-Folding Initiation Structures in Ribonuclease A: Conformational Analysis of trans-Ac-Asn-Pro-Tyr NHMe and trans-Ac-Tyr-Pro-Asn-NHMe in Water and in the Solid State (1985) (0)
- Stereocontrolled Functionalization in the Cyclohexane Ring Using Organomolybdenum Chemistry. (1985) (0)
- Bacterially produced small molecules stimulate diatom growth (2020) (0)
- Jaspamide (I), a Modified Peptide from a Jaspis Sponge, with Insecticidal and Antifungal Activity. (1986) (0)
- Crystallization and preliminary X-ray crystallographic analysis of the Pseudomonas aeruginosa cyclohexadienyl dehydratase. (1999) (0)
- Decision letter: Convergent evolution of small molecule pheromones in Pristionchus nematodes (2020) (0)
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